Digital Commons Network^™

Tweets To A Young 1l, Rachel I. Gurvich

Faculty Publications

A series of eleven tweets ruminating about the author's law school experience received a positive and enthusiastic response from many lawyers, law professors, and law students, and ultimately caught the eye of one of the Green Bag’s editors. This short piece unpacks and contextualizes those tweets. The original tweets appear below, numbered as they first appeared on Twitter.

Towards A Series Of Academic Norms For #Lawprof Twitter, Carissa Byrne Hessick

Faculty Publications

Tentative thoughts on what professional norms ought to apply to law professors who engage in a now popular form of public discourse: Twitter. Specifically, it is suggested that law professors should assume that, each time they tweet about a legal issue, they are making an implicit claim to expertise about that issue. It is also suggested that when law professors participate on Twitter, they should do so in a fashion that models the sort of reasoned debate taught to law students.

High Circulatory Leptin Mediated Nox-2-Peroxynitrite-Mir21 Axis Activate Mesangial Cells And Promotes Renal Inflammatory Pathology In Nonalcoholic Fatty Liver Disease, Firas Alhasson, Ratanesh K. Seth, Sutapa Sarkar, Diana A. Kimono, Muayad S. Albadrani, Diptadip Dattaroy, Varun Chandrashekaran, Geoffry Scott, Samir Raychoudhury, Mitzi Nagarkatti, Prakash Nagarkatti, Anna Mae Diehl, Saurabh Chatterjee

Faculty Publications

High circulatory insulin and leptin followed by underlying inflammation are often ascribed to the ectopic manifestations in non-alcoholic fatty liver disease (NAFLD) but the exact molecular pathways remain unclear. We have shown previously that CYP2E1-mediated oxidative stress and circulating leptin in NAFLD is associated with renal disease severity. Extending the studies, we hypothesized that high circulatory leptin in NAFLD causes renal mesangial cell activation and tubular inflammation via a NOX2 dependent pathway that upregulates proinflammatory miR21. High-fat diet (60% kcal) was used to induce fatty liver phenotype with parallel insulin and leptin resistance. The kidneys were probed for mesangial cell …

Differently Abled Staff Welcomed By Library Recruiters, Bec Muir Aalia, Kim M. Thompson, M. Asim Qayyum

Faculty Publications

The article focuses on the benefits of reading therapy for improving health and well being for people living with disability. Topics discussed include providing knowledge or skills to provide services or resources to people living with a disability; encouraging library employers to form job advertisement with diversity and disability in mind; and encouraging employment of the same.

The Tragedy Of Child And Adolescent Suicide, Brad Hinman

Faculty Publications

"In 2015, the Centers for Disease Control and U.S. Department of Education reported that 20 to 28 percent of U.S. students in grades 6 to 12 have experienced bullying, 30 percent admitted to bullying others, and 70 percent witnessed bullying in some form. According to the report, children and young adults are affected by bullying and cyberbullying during their school-age years, and some even into adulthood.³ “School violence and bullying occurs throughout the world and affects a significant proportion of children and adolescents. It is estimated that 246 million children and adolescents experience school violence and bullying in …

Longitudinal Change In Parent-Adolescent Communication About Sexuality, Laura M. Padilla-Walker

Faculty Publications

Purpose: Research suggests that parents can be important sources of sex education for their children, but we know little about how this type of communication changes developmentally. Thus, the current study explored longitudinal change in child-, mother-, and father-reports of parent-child communica- tion about sexuality, and how change might be associated with behaviors indicative of sexual risk.

Methods: The sample included 468 adolescents (52% female, 67% white) who participated every year from age 14 to 18, and their mother and father. Results: Growth-curve analyses revealed relatively low and stable levels of parent-child communication from all three reporters, with some differences …

Spatial Assessment Of Water Quality With Urbanization In 2007-2015, Shanghai, China, Huixuan Li, Cuizhen Wang, Xiao Huang, Andrew Hug

Faculty Publications

Shanghai, as one of the megacities and economic centers of China, is facing critical water quality challenges. This study analyzed the impact of urbanization on the water quality in Shanghai, from 2007 to 2015, using remote sensing (RS) and geographic information system (GIS) techniques. Five measurements of water quality were employed: total discharged wastewater volume, general water quality levels, dissolved oxygen (DO), permanganate, and ammonia nitrogen. The impacts of urban land-use changes on water quality were examined. An urban index was extracted from satellite image classification and was used to quantify the anthropogenic activities. In the watershed level, unit watersheds …

Disclosure Of Homosexual Behaviors To Healthcare Providers And Uptake Of Hiv Testing For Men Who Have Sex With Men: A Systematic Review., Shan Qiao Ph.D., Guangyu Zhou, Xiaoming Li

Faculty Publications

To promote HIV-testing and offer optimal care for men who have sex with men (MSM), health-care providers (HCPs) must first be aware of their patients’ sexual behaviors. Otherwise, HCPs may overlook MSM’s risks for HIV infection and their special health-care needs. For MSM, reporting their same-sex behaviors to HCPs (disclosure to HCPs) may promote their linkage to HIV prevention and treatment cascade and improve their health outcomes. No literature review has been conducted to examine the relationship between disclosure to HCPs and uptake of HIV-testing among MSM. The current study reviewed and synthesized findings from 29 empirical studies published in …

Development And Validation Of The Study Quality Assessment Of Design (Squad) Tool For Systematic Reviews, Aaron Tierney, Marie Haverfield, Shreyas Bharadwaj, Donna Zulman

Faculty Publications

Research Objective: Quality assessment is an important factor in making sure results garnered from systematic reviews have external validity. While established groups have made recommendations and developed tools for quality assessment, these tools are often complex and not applicable across multiple types of study designs, generating challenges for quality assessment efforts.Study Design: As part of a systematic review of interpersonal interventions associated with the Quadruple Aim (population health, cost, patient and provider experience), we reviewed and developed a novel tool to measure the quality of study design for included studies. A multidisciplinary team reviewed existing quality assessment tools and ranked …

Mhealth Technology Use And Implications In Historically Underserved And Minority Populations In The United States: Systematic Literature Review, Charkarra Anderson-Lewis, Gabrielle Darville, Rebeccah Eve Mercado, Savannah Howell, Samantha Di Maggio

Faculty Publications

Background: The proportion of people in the United States who are members of at least two ethnic groups is projected to increase to 10% by the year 2050. This makes addressing health disparities and health inequities in minority populations increasingly more difficult. Minority populations, including those who classify themselves as African American and Hispanic, are using mobile phones to access health information via the internet more frequently than those who classify themselves as white, providing unique opportunities for those in public health and health education to reach these traditionally underserved populations using mobile health (mHealth) interventions.

Objective: The objective of …

Tetrafluorobenzo-Fused Bodipy: A Platform For Regioselective Synthesis Of Bodipy Dye Derivatives, Andrea Savoldelli, Qianli Meng, Roberto Paolesse, Frank R. Fronczek, Kevin M. Smith, M. Graça H. Vicente

Faculty Publications

© 2018 American Chemical Society. A novel route for the synthesis of unsymmetrical benzo-fused BODIPYs is reported using 4,5,6,7-tetrafluoroisoindole as a precursor. The reactivity of the 3,5-dibromo tetrafluorobenzo-fused BODIPY was investigated under nucleophilic substitution and Pd(0)-catalyzed cross-coupling reaction conditions. In addition to the 3,5-bromines, one α-fluoro group on the benzo-fused ring can also be functionalized, and an unusual homocoupling with formation of a bisBODIPY was observed. This new class of fluorinated BODIPYs could find various applications in medicine and materials.

Circadiomics: Circadian Omic Web Portal, Nicholas Ceglia, Yu Liu, Siwei Chen, Forest Agostinelli, Kristin Eckel-Mahan, Paolo Sassone-Corsi, Pierre Baldi

Faculty Publications

Circadian rhythms play a fundamental role at all levels of biological organization. Understanding the mechanisms and implications of circadian oscillations continues to be the focus of intense research. However, there has been no comprehensive and integrated way for accessing and mining all circadian omic datasets. The latest release of CircadiOmics (http://circadiomics.ics.uci.edu) fills this gap for providing the most comprehensive web server for studying circadian data. The newly updated version contains high-throughput 227 omic datasets corresponding to over 74 million measurements sampled over 24 h cycles. Users can visualize and compare oscillatory trajectories across species, tissues and conditions. Periodicity statistics (e.g. …

Ten Weeks Of High-Intensity Interval Walk Training Is Associated With Reduced Disease Activity And Improved Innate Immune Function In Older Adults With Rheumatoid Arthritis: A Pilot Study, David B. Bartlett, Leslie H. Willis, Cris A. Slentz, Andrew Hoselton, Leslie Kelly, Janet L. Huebner, Virginia B. Kraus, Jennifer Moss, Michael J. Muehlbauer, Guillaume Spielmann, William E. Kraus, Janet M. Lord, Kim M. Huffman

Faculty Publications

Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease in which adults have significant joint issues leading to poor health. Poor health is compounded by many factors, including exercise avoidance and increased risk of opportunistic infection. Exercise training can improve the health of patients with RA and potentially improve immune function; however, information on the effects of high-intensity interval training (HIIT) in RA is limited. We sought to determine whether 10 weeks of a walking-based HIIT program would be associated with health improvements as measured by disease activity and aerobic fitness. Further, we assessed whether HIIT was associated with improved …

Are The Stock Markets "Rigged"? An Empirical Analysis Of Regulatory Change, Stephen Diamond

Faculty Publications

Are the stock markets "rigged"? An empirical analysis of regulatory change: Volatile events in the stock market such as the 2010 Flash Crash have sparked concern that financial markets are “rigged” in favor of trading firms that use high frequency trading (“HFT”) systems. We analyze a regulatory change implemented by the SEC in 2007 by examining its effect on a key market metric, the bid-ask spread, an investor cost, and find that the regulatory shift, indeed, disadvantages investors. We link the implementation of this change to a shift in the volume of trades from a low-cost venue to a high-cost …

Stability, Persistence And Habitat Associations Of The Pearl Darter Percina Aurora In The Pascagoula River System, Southeastern Usa, Scott R. Clark, William T. Slack, Brian Kreiser, Jacob F. Schaefer, Mark A. Dugo

Faculty Publications

The southeastern United States represents one of the richest collections of aquatic biodiversity worldwide; however, many of these taxa are under an increasing threat of imperilment, local extirpation, or extinction. The pearl darter Percina aurora is a small-bodied freshwater fish endemic to the Pearl and Pascagoula river systems of Mississippi and Louisiana (USA). The last collected specimen from the Pearl River drainage was taken in 1973, and it now appears that populations in this system are likely extirpated. This reduced the historical range of this species by approximately 50%, ultimately resulting in federal protection under the US Endangered Species Act …

Honey Bee Survival And Pathogen Prevalence: From The Perspective Of Landscape And Exposure To Pesticides, Mohamed Alburaki, Deniz Chen, John A. Skinner, William G. Meikle, David R. Tarpy, John Adamczyk, Scott D. Stewart

Faculty Publications

In order to study the in situ effects of the agricultural landscape and exposure to pesticides on honey bee health, sixteen honey bee colonies were placed in four different agricultural landscapes. Those landscapes were three agricultural areas with varying levels of agricultural intensity (AG areas) and one non-agricultural area (NAG area). Colonies were monitored for different pathogen prevalence and pesticide residues over a period of one year. RT-qPCR was used to study the prevalence of seven different honey bee viruses as well as Nosema sp. in colonies located in different agricultural systems with various intensities of soybean, corn, sorghum, and …

Best Practices For Developing And Validating Scales For Health, Social, And Behavioral Research: A Primer, Godfred O. Boateng, Torsten B. Neilands, Edward A. Frongillo Jr., Hugo R. Melgar-Quiñonez, Sera L. Young

Faculty Publications

Scale development and validation are critical to much of the work in the health, social, and behavioral sciences. However, the constellation of techniques required for scale development and evaluation can be onerous, jargon-filled, unfamiliar, and resource-intensive. Further, it is often not a part of graduate training. Therefore, our goal was to concisely review the process of scale development in as straightforward a manner as possible, both to facilitate the development of new, valid, and reliable scales, and to help improve existing ones. To do this, we have created a primer for best practices for scale development in measuring complex phenomena. …

Social Entrepreneurship In China: Driving Institutional Change, Tonia Warnecke

Faculty Publications

In the aftermath of the Great Recession, the concern with exclusionary and unethical business practices has led to the growing popularity of social entrepreneurship, which focuses on the creation of social value, not wealth. In this article, I reflect on social entrepreneurship in China, a unique context given the strong Communist party leadership and the transition to a market economy. To begin, I discuss the legal and political framework for social entrepreneurship in China, followed by an overview of the sector’s characteristics, including age, size, social issues emphasized, leader characteristics, and the role of women. Next, I provide examples of …

The First World War (A Database Review), Patti Mccall-Wright

Faculty Publications

The First World War offers primary and secondary digitized content spread over four modules. The first module, Personal Experiences, focuses on the daily lives of men and women during wartime and addresses issues such as trench warfare, battle, training, death, and daily life in the military. The materials found in this module include diaries, letters, oral histories, cartoons, trench maps, and even sheet music. Propaganda and Recruitment addresses morale, censorship, recruitment, dissension, and propaganda development and includes posters, recruitment materials, tribunal case files, and papers from the UK Ministry of Information and the Kriegspresseamt in Berlin. Visual Perspectives and Narratives …

Assessing Pyrite-Derived Sulfate In The Mississippi River With Four Years Of Sulfur And Triple-Oxygen Isotope Data, Bryan A. Killingsworth, Huiming Bao, Issaku E. Kohl

Faculty Publications

© 2018 American Chemical Society. Riverine dissolved sulfate (SO42-) sulfur and oxygen isotope variations reflect their controls such as SO42- reduction and reoxidation, and source mixing. However, unconstrained temporal variability of riverine SO42- isotope compositions due to short sampling durations may lead to mischaracterization of SO42- sources, particularly for the pyrite-derived sulfate load. We measured the sulfur and triple-oxygen isotopes (δ34S, δ18O, and Δ′17O) of Mississippi River SO42- with biweekly sampling between 2009 and 2013 to test isotopic variability and constrain sources. Sulfate δ34S and δ18O ranged from -6.3‰ to -0.2‰ and -3.6‰ to +8.8‰, respectively. Our sampling period captured …

Assessing Pyrite-Derived Sulfate In The Mississippi River With Four Years Of Sulfur And Triple-Oxygen Isotope Data, Bryan A. Killingsworth, Huiming Bao, Issaku E. Kohl

Faculty Publications

© 2018 American Chemical Society. Riverine dissolved sulfate (SO42-) sulfur and oxygen isotope variations reflect their controls such as SO42- reduction and reoxidation, and source mixing. However, unconstrained temporal variability of riverine SO42- isotope compositions due to short sampling durations may lead to mischaracterization of SO42- sources, particularly for the pyrite-derived sulfate load. We measured the sulfur and triple-oxygen isotopes (δ34S, δ18O, and Δ′17O) of Mississippi River SO42- with biweekly sampling between 2009 and 2013 to test isotopic variability and constrain sources. Sulfate δ34S and δ18O ranged from -6.3‰ to -0.2‰ and -3.6‰ to +8.8‰, respectively. Our sampling period captured …

Cohort Profile: The Maternal And Infant Nutrition Interventions In Matlab (Minimat) Cohort In Bangladesh, Shams El Arifeen, Eva-Charlotte Ekström, Edward A. Frongillo Jr., Jena Hamadani, Ashraful I. Khan, Ruchira T. Naved, Anisur Rahman, Rubhana Raqib, Kathleen M. Rasmussen, Katarina Ekholm Selling, Yukiko Wagatsuma, Lars Åke Persson

Faculty Publications

No abstract provided.

Patient Acceptance Of Remote Scribing Powered By Google Glass In Outpatient Dermatology: Cross-Sectional Study, Sandra Odenheimer, Deepika Goyal, Veena Jones, Ruth Rosenblum, Lam Ho, Albert Chan

Faculty Publications

Background: The ubiquitous use of electronic health records (EHRs) during medical office visits using a computer monitor and keyboard can be distracting and can disrupt patient-health care provider (HCP) nonverbal eye contact cues, which are integral to effective communication. Provider use of a remote medical scribe with face-mounted technology (FMT), such as Google Glass, may preserve patient-HCP communication dynamics in health care settings by allowing providers to maintain direct eye contact with their patients while still having access to the patient’s relevant EHR information. The medical scribe is able to chart patient encounters in real-time working in an offsite location, …

Bulk Biometric Metadata Collection, Margaret Hu

Faculty Publications

Smart police body cameras and smart glasses worn by law enforcement increasingly reflect state-of-the-art surveillance technology, such as the integration of live-streaming video with facial recognition and artificial intelligence tools, including automated analytics. This Article explores how these emerging cybersurveillance technologies risk the potential for bulk biometric metadata collection. Such collection is likely to fall outside the scope of the types of bulk metadata collection protections regulated by the USA FREEDOM Act of 2015. The USA FREEDOM Act was intended to bring the practice of bulk telephony metadata collection conducted by the National Security Agency (“NSA”) under tighter regulation. In …

Species Richness And Phylogenetic Diversity Of Native And Non-Native Species Respond Differently To Area And Environmental Factors, Daijiang Li, William B. Monahan, Benjamin Baiser

Faculty Publications

© 2018 John Wiley & Sons Ltd Aim: To test whether native and non-native species have similar diversity–area relationships (species–area relationships [SARs] and phylogenetic diversity–area relationships [PDARs]) and whether they respond similarly to environmental variables. Location: United States. Methods: Using lists of native and non-native species as well as environmental variables for >250 US national parks, we compared SARs and PDARs of native and non-native species to test whether they respond similarly to environmental conditions. We then used multiple regressions involving climate, land cover and anthropogenic variables to further explore underlying predictors of diversity for plants and birds in US …

Generating Dna Sequence Data With Limited Resources For Molecular Biology: Lessons From A Barcoding Project In Indonesia, Gillian H. Dean, Rani Asmarayani, Marlina Ardiyani, Yessi Santika, Teguh Triono, Sarah Mathews, Campbell O. Webb

Faculty Publications

Applications in Plant Sciences is published by Wiley Periodicals, Inc. on behalf of the Botanical Society of America The advent of the DNA sequencing age has led to a revolution in biology. The rapid and cost-effective generation of high-quality sequence data has transformed many fields, including those focused on discovering species and surveying biodiversity, monitoring movement of biological materials, forensic biology, and disease diagnostics. There is a need to build capacity to generate useful sequence data in countries with limited historical access to laboratory resources, so that researchers can benefit from the advantages offered by these data. Commonly used molecular …

Teaching Health Impact And Behavior With Infographics, Rosemary M. Caron, Eugenia Opuda, Benjamin Peck

Faculty Publications

The use of Infographics can be a tool that not only allows for the communication of empirical health data in an understandable format, but encourages the health administration student to present evidence-based research in a creative manner. The purpose of this paper is to describe a learning exercise that implements Infographics to demonstrate an impact of a health issue and/or encourage a health behavior change. This learning exercise is developed to increase student knowledge and visual literacy skills with respect to presenting, in a concise format, a well-researched and referenced health issue and/or a health behavior change. Specifically, the exercise …

Groundsel Bush (Baccharis Halimifolia) Extract Promotes Adipocyte Differentiation In Vitro And Increases Adiponectin Expression In Mature Adipocytes, Anik Boudreau, Scott Fuller, Davidm Ribnicky, Allison J. Richard, Jacqueline M. Stephens

Faculty Publications

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. An ethanolic extract of Baccharis halimifolia (groundsel bush, GB), which is a native Louisiana plant with documented use in Creole folk medicine, has been shown to inhibit lipopolysaccharide (LPS)-induced inflammation in cultured macrophages. Here, we examine the effects of GB on adipocyte development and function, as these processes are attractive targets for intervention in insulin resistance. Oil Red O neutral lipid staining, reverse transcription-quantitative polymerase chain reaction (RT-qPCR), and immunoblotting were used to measure GB effects on lipid accumulation, gene expression, and protein abundance, respectively. In differentiating 3T3-L1 adipocytes, GB enhanced …

Blood Pressures Are Going Down Worldwide—But Why?, Julia A. Critchley, Richard S. Cooper

Faculty Publications

No abstract provided.

Changes To Extender, Cryoprotective Medium, And In Vitro Fertilization Improve Zebrafish Sperm Cryopreservation, Jennifer L. Matthews, Joy M. Murphy, Carrie Carmichael, Huiping Yang, Terrence Tiersch, Monte Westerfield, Zoltan M. Varga

Faculty Publications

Sperm cryopreservation is a highly efficient method for preserving genetic resources. It extends the reproductive period of males and significantly reduces costs normally associated with maintenance of live animal colonies. However, previous zebrafish (Danio rerio) cryopreservation methods have produced variable outcomes and low post-thaw fertilization rates. To improve post-thaw fertilization rates after cryopreservation, we developed a new extender and cryoprotective medium (CPM), introduced quality assessment (QA), determined the optimal cooling rate, and improved the post-thaw in vitro fertilization process. We found that the hypertonic extender E400 preserved motility of sperm held on ice for at least 6 h. We implemented …