Digital Commons Network^™

Bidirectional Interference Between Simulated Driving And Speaking, Christopher Dromey, Kelsey Simmons

Faculty Publications

Purpose: This study relied on acoustic measures of connected speech and several indices of driving performance to quantify interference between speaking and simulated driving. Method: Three groups of 20 younger (ages 20–30 years), middle-age (ages 40–50 years), and older (ages 60–71 years) adults produced monologues and completed a simulated driving task, which involved maintaining a constant speed and lane position on a freeway. Both tasks were completed separately and concurrently. Results: There were significant divided attention effects, with a reduced speaking time ratio, and increases in vocal intensity, speed variability, and steering wheel adjustments. There was a significant between-subjects age …

Listeners’ Ability To Identify The Gender Of Preadolescent Children In Different Linguistic Contexts, Christopher Dromey, Shawn Nissen, Sharalee Blunck, Anita Dromey

Faculty Publications

This study evaluated listeners’ ability to identify the gender of preadolescent children from speech samples of varying length and linguistic context. The listeners were presented with a total of 190 speech samples in four different categories of linguistic context: segments, words, sentences, and discourse. The listeners were instructed to evaluate each speech sample and decide whether the speaker was a male or female and rate their level of confidence in their decision. Results showed listeners identified the gender of the speakers with a high degree of accuracy, ranging from 86% to 95%. Significant differences in listener judgments were found across …

Increasing English Learners’ Positive Emotional Response To Learning Through Dance, Grant Eckstein, Elizabeth Hanks

Faculty Publications

This study investigates dance as an English Second Language (ESL) curriculum enhancement. The curriculum utilizes kinesthetic learning, which is a method seldom incorporated in formal academic classrooms (Pourhosein Gilakjani, 2011) despite evidence suggesting that it benefits all students, including those without kinesthetic learning preferences (Schumann, 1997). Supporters believe that the benefits of incorporating movement in the classroom include increased student enjoyment, motivation, and confidence in learning. However, these beliefs are merely anecdotal at present. This study analyzes quantitative questionnaires and qualitative feedback from 26 students who participated in a 4-week long Dance ESL curriculum to determine whether dance-based learning can …

Key Mechanisms By Which Post-Icu Activities Can Improve In-Icu Care: Results Of The International Thrive Collaboratives, Kimberley J. Haines, Carla M. Sevin, Elizabeth Hibbert, Leanne M. Boehme, Krishna Aparanji, Rita N. Bakhru, Anthony J. Bastin, Sarah J. Beesley, Brad W. Butcher, Kelly Drumright, Tammy L. Eaton, Thomas Farley, Penelope Firshman, Andrew Fritschle, Clare Holdsworth, Aluko A. Hope, Annie Johnson, Michael T. Kenes, Babar A. Khan, Janet A. Kloos, Erin K. Kross, Belinda J. Macleod‑Smith, Pamela Mactavish, Joel Meyer, Ashley Montgomery‑Yates, Tara Quasim, Howard L. Saft, Andrew Slack, Joanna Stollings, Gerald Weinhouse, Jessica Whitten, Giora Netzer, Ramona O. Hopkins, Mark E. Mikkelsen, Theodore J. Iwashyna, Joanne Mcpeake

Faculty Publications

Objective: To identify the key mechanisms that clinicians perceive improve care in the intensive care unit (ICU), as a result of their involvement in post-ICU programs.

Methods: Qualitative inquiry via focus groups and interviews with members of the Society of Critical Care Medicine’s THRIVE collaborative sites (follow-up clinics and peer support). Framework analysis was used to synthesize and inter‑ pret the data.

Results: Five key mechanisms were identifed as drivers of improvement back into the ICU: (1) identifying other‑ wise unseen targets for ICU quality improvement or education programs—new ideas for quality improvement were generated and greater attention paid to …

Efficacy Of Weight Loss Intervention Can Be Predicted Based On Early Alterations Of Fmri Food Cue Reactivity In The Striatum, Petra Hermann, Viktor Gál, István Kóbor, C. Brock Kirwan, Peter Kovacs, Tama Kitkas, Zsuzsanna Lengyel, Eszter Balint, Balázs Varga, Csongor Cseko, Zoltan Vidnyanszky

Faculty Publications

Increased fMRI food cue reactivity in obesity, i.e. higher responses to high- vs. low-calorie food images, is a promising marker of the dysregulated brain reward system underlying enhanced susceptibility to obesogenic environmental cues. Recently, it has also been shown that weight loss interventions might affect fMRI food cue reactivity and that there is a close association between the alteration of cue reactivity and the outcome of the intervention. Here we tested whether fMRI food cue reactivity could be used as a marker of diet-induced early changes of neural processing in the striatum that are predictive of the outcome of the …

Constructing Meaning Through Connection: Religious Perspectives On The Purpose Of Life, Quinn Galbraith, Adam Callister, Heather Kelly

Faculty Publications

Given prior research, which establishes a connection between religiosity and an increased sense of meaning in life, this study draws on qualitative data from interviews with 172 religious individuals living in Ireland and the United Kingdom in order to analyze what religious individuals perceive as their purpose in life. Interviews were conducted in person, recorded, transcribed verbatim, and coded utilizing a team-based methodology. Researchers identified three main themes from the data related to the idea that the purpose of life is tied to relationships and connection: love and service toward others, family relationships, and connection with God. An analysis of …

Associations Of Ambivalent Leadership With Distress And Cortisol Secretion, Wendy C. Birmingham, Raphael M. Herr, Frenk Van Harreveld, Bert N. Uchino, Adrian Loerbroks, Joachim E. Fischer, Jos A. Bosch

Faculty Publications

Ambivalent social ties, i.e., whereby a relationship is evaluated simultaneously in positive and negative terms, are a potential source of distress and can perturb health-relevant biological functions. Social interactions at the workplace, in particular with supervisors, are often described in ambivalent terms, but the psychological and psychobiological impact of such interactions has received little scientific attention. The current study examined associations between ambivalent attitudes towards one’s supervisor, perceived distress (general and work-related), and diurnal dynamics of the stress hormone cortisol. 613 employees evaluated their supervisor in terms of positive and negative behaviors, which was combined into an ambivalent index. Higher …

Spousal Influence: A Study Of Women With Eating And Body Image Concerns, Wendy C. Birmingham, Adriane Ito De Queiroz Cavallini, Jordan Sgro

Faculty Publications

Eating disorder literature often overlooks those exhibiting eating and body image concerns without an eating disorder diagnosis. Supportive spouses may ameliorate negative body image and eating behavior, but spouses who exhibit both supportive and non-supportive behaviors concurrently (ambivalent) may send mixed messages. Eating disorder behaviors and spousal interactions were assessed in 61 women who demonstrated eating disordered behavior and body dissatisfaction but were not clinically diagnosed with an eating disorder. Spouses mostly provided messages of reassurance. However, some women were unable to overcome their internalized negative body image. Feelings of social comparison were seen with ambivalent spouses. Supportive relationships may …

The Structure Of Competence: Evaluating The Factor Structure Of The Cognitive Therapy Rating Scale, Scott A. Baldwin, Simon B. Goldberg, Kritzia Merced, Derek D. Caperton, Zac E. Imel, David C. Atkins, Torrey Creed

Faculty Publications

The Cognitive Therapy Rating Scale (CTRS) is an observer-rated measure of cognitive behavioral therapy (CBT) treatment fidelity. Although widely used, the factor structure and psychometric properties of the CTRS are not well established. Evaluating the factorial validity of the CTRS may increase its utility for training and fidelity monitoring in clinical practice and research. The current study used multilevel exploratory factor analysis to examine the factor structure of the CTRS in a large sample of therapists (n = 413) and observations (n = 1,264) from community-based CBT training. Examination of model fit and factor loadings suggested that three within-therapist factors …

Moral Development In Business Ethics: An Examination And Critique, Kristen Bell Detienne, Carol Frogley Ellertson, Marc-Charles Ingerson, William R. Dudley

Faculty Publications

The field of behavioral ethics has seen considerable growth over the last few decades. One of the most significant concerns facing this interdisciplinary field of research is the moral judgment-action gap. The moral judgment-action gap is the inconsistency people display when they know what is right but do what they know is wrong. Much of the research in the field of behavioral ethics is based on (or in response to) early work in moral psychology and American psychologist Lawrence Kohlberg’s foundational cognitive model of moral development. However, Kohlberg’s model of moral development lacks a compelling explanation for the judgment-action gap. …

Screening For Posttraumatic Stress Disorder In Ards Survivors: Validation Of The Impact Of Event Scale-6 (Ies-6), Megan M. Hosey, Jeannie-Marie S. Leoutsakos, Ximin Li, Victor D. Dinglas, O. Joseph Bienvenu, Ann M. Parker, Ramona O. Hopkins Phd, Dale M. Needham, Karin J. Neufeld

Faculty Publications

Background: Posttraumatic stress disorder (PTSD) symptoms are common in acute respiratory distress syndrome (ARDS) survivors. Brief screening instruments are needed for clinical and research purposes. We evaluated internal consistency, external construct, and criterion validity of the Impact of Event Scale-6 (IES-6; 6 items) compared to the original Impact of Event Scale—Revised (IES-R; 22 items) and to the Clinician Administered PTSD Scale (CAPS) reference standard evaluation in ARDS survivors.

Methods: This study is a secondary analysis from two independent multi-site, prospective studies of ARDS survivors. Measures of internal consistency, and external construct and criterion validity were evaluated.

Results: A total of …

Domain Rearrangement And Denaturation In Ebola Virus Protein Vp40, Rudramani Pokhrel, Pornthep Sompornpisut, Prem Chapagain, Brian Olson, Bernard Gertsman, Ras B. Pandey

Faculty Publications

The VP40 protein plays a critical role in coordinating the virion assembly, budding, and replication of the Ebola virus. Efforts have been made in recent years to understand various aspects of VP40 structure, dynamics, and function such as assembly of the protein and its roles in virus replication and penetration of the protein into the plasma membrane. A major conformational transformation is necessary for VP40 to form some of its oligomeric structures and to perform various functions. This conformational change from a compact structure with the N-terminal domain (NTD) and C-terminal domain (CTD) closely associated involves a dissociation or springing-out …

Dynamic Responses And Implications To Coastal Wetlands And The Surrounding Regions Under Sea Level Rise, Karim Alizad, Scott C. Hagen, Stephen C. Medeiros, Matthew V. Bilskie, James T. Morris, Len Balthis, Christine A. Buckel

Faculty Publications

Two distinct microtidal estuarine systems were assessed to advance the understanding of the coastal dynamics of sea level rise in salt marshes. A coupled hydrodynamic-marsh model (Hydro-MEM) was applied to both a marine-dominated (Grand Bay, Mississippi) and a mixed fluvial/marine (Weeks Bay, Alabama) system to compute marsh productivity, marsh migration, and potential tidal inundation from the year 2000 to 2100 under four sea level rise scenarios. Characteristics of the estuaries such as geometry, sediment availability, and topography, were compared to understand their role in the dynamic response to sea level rise. The results show that the low sea level rise …

Differential Expression Of Genes Related To Innate Immune Responses In Ex Vivo Spinal Cord And Cerebellar Slice Cultures Infected With West Nile Virus, Parminder J.S. Vig, Deyin Lu, Amber M. Paul, Ram Kuwar, Maria Lopez, Dobrivoje S. Stokic, A. Arturo Leis, Michael R. Garrett, Fengwei Bai

Faculty Publications

West Nile virus (WNV) infection results in a spectrum of neurological symptoms, ranging from a benign fever to severe WNV neuroinvasive disease with high mortality. Many who recover from WNV neuroinvasive infection present with long-term deficits, including weakness, fatigue, and cognitive problems. While neurons are a main target of WNV, other cell types, especially astrocytes, play an important role in promoting WNV-mediated central nervous system (CNS) damage. Conversely, it has been shown that cultured primary astrocytes secrete high levels of interferons (IFNs) immediately after WNV exposure to protect neighboring astrocytes, as well as neurons. However, how intrinsic responses to WNV …

Speech Fluency In Acquired Apraxia Of Speech During Narrative Discourse: Group Comparisons And Dual Task Effects, Tyson G. Harmon, Adam Jacks, Katarina L. Haley

Faculty Publications

Purpose: Slowed speech and interruptions to the flow of connected speech are common in aphasia. These features are also observed during dual task performance for neurotypical adults. The purposes of this study were to determine (a) whether indices of fluency related to cognitive-linguistic versus motor processing would differ between speakers with aphasia plus AOS and speakers with aphasia only and (b) whether cognitive load reduces fluency in speakers with aphasia with and without AOS.

Method: Fourteen speakers with aphasia (seven with AOS) and seven neurotypical controls retold short stories alone (single task) and while simultaneously distinguishing between a high and …

Resveratrol Attenuates Allergic Asthma And Associated Inflammation In The Lungs Through Regulation Of Mirna-34a That Targets Foxp3 In Mice, Esraah Alharris, Hasan Alghetaa, Ratanesh K. Seth, Saurabh Chatterjee, Narendra P. Singh, Mitzi Nagarkatti, Prakash Nagarkatti

Faculty Publications

Asthma is a chronic inflammatory disease of airways mediated by T-helper 2 (Th2) cells involving complex signaling pathways. Although resveratrol has previously been shown to attenuate allergic asthma, the role of miRNA in this process has not been studied. We investigated the effect of resveratrol on ovalbumin-induced experimental allergic asthma in mice. To that end, BALB/c mice were immunized with ovalbumin (OVA) intraperitoneally followed by oral gavage of vehicle (OVA-veh) or resveratrol (100 mg/kg body) (OVA-res). On day 7, the experimental groups received intranasal challenge of OVA followed by 7 days of additional oral gavage of vehicle or resveratrol. At …

Positive Association Between Dietary Inflammatory Index And The Risk Of Osteoporosis: Results From The Koges_Health Examinee (Hexa) Cohort Study, Hye Sun Kim, Cheongmin Sohn, Minji Kwon, Woori Na, Nitin Shivappa, James R. Hébert, Mi Kyung Kim

Faculty Publications

Previous studies have found that diet’s inflammatory potential is related to various diseases. However, little is known about its relationship with osteoporosis. The aim of this study was to investigate the association between the dietary inflammatory index (DII®) and osteoporosis risk in a large-scale prospective cohort study in Korea. This prospective cohort study included 159,846 participants (men 57,740; women 102,106) from South Korea with a mean follow-up of 7.9 years. The DII was calculated through a validated semi-quantitative FFQ (SQFFQ), and information on osteoporosis was self-reported by the participants. Analyses were performed by using a multivariable Cox proportional hazard model. …

Precision Of Provider Licensure Data For Mapping Member Accessibility To Medicaid Managed Care Provider Networks, Nathaniel Bell, Ana Lòpez-Defede, Rebecca Wilkerson, Kathy Mayfield-Smith

Faculty Publications

BACKGROUND:

In July 2018, the Centers for Medicare and Medicaid Services (CMS) updated its Medicaid Managed Care (MMC) regulations that govern network and access standards for enrollees. There have been few published studies of whether there is accurate geographic information on primary care providers to monitor network adequacy.

METHODS:

We analyzed a sample of nurse practitioner (NP) and physician address data registered in the state labor, licensing, and regulation (LLR) boards and the National Provider Index (NPI) using employment location data contained in the patient-centered medical home (PCMH) data file. Our main outcome measures were address discordance (%) at the …

Secondary Organic Aerosol Production From Local Emissions Dominates The Organic Aerosol Budget Over Seoul, South Korea, During Korus-Aq, Benjamin A. Nault, Pedro Campuzano-Jost, Douglas A. Day, Jason C. Schroder, Bruce Anderson, Andreas J. Beyersdorf, Donald R. Blake, William H. Brune, Yonghoon Choi, Chelsea A. Corr, Joost A. De Gouw, Jack E. Dibb, Joshua P. Digangi, Glenn S. Diskin, Alan Fried, L. Gregory Huey, Michelle J. Kim, Christoph J. Knote, Kara D. Lamb, Taehyoung Lee, Taehyun Park, Sally E. Pusede, Eric Scheuer, Kenneth L. Thornhill, Jung-Hun Woo, Jose L. Jimenez

Faculty Publications

Organic aerosol (OA) is an important fraction of submicron aerosols. However, it is challenging to predict and attribute the specific organic compounds and sources that lead to observed OA loadings, largely due to contributions from secondary production. This is especially true for megacities surrounded by numerous regional sources that create an OA background. Here, we utilize in situ gas and aerosol observations collected on board the NASA DC-8 during the NASA–NIER KORUS-AQ (Korea–United States Air Quality) campaign to investigate the sources and hydrocarbon precursors that led to the secondary OA (SOA) production observed over Seoul. First, we investigate the contribution …

Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi

Faculty Publications

The U. S. Gulf of Mexico is experiencing a dramatic increase in tidal marsh restoration actions, which involves planting coastal areas with smooth cordgrass (Spartina alterniflora) and black needlerush (Juncus roemerianus) for erosion control and to provide habitat for fish and wildlife. It can take decades for sedimentary cycles in restored marshes to approach reference conditions, and the contribution of the sediment microbial communities to these processes is poorly elucidated. In this study, we addressed this gap by comparing rhizosphere microbiomes of S. alterniflora and J. roemerianus from two restored marshes and a natural reference marsh located at Deer Island, …

Visualizing Stochastic Actor-Based Model Microsteps, Jimi Adams, David R. Schaefer

Faculty Publications

This visualization provides a dynamic representation of the microsteps involved in modeling network and behavior change with a stochastic actor-based model. This video illustrates how (1) observed time is broken up into a series of simulated microsteps and (2) these microsteps serve as the opportunity for actors to change their network ties or behavior. The example model comes from a widely used tutorial, and we provide code to allow for adapting the visualization to one’s own model.

Identification Of Experimental And Control Areas For Cctv Effectiveness Assessment—The Issue Of Spatially Aggregated Data, Adam Dabrowski, Piotr Matczak, Andrzej Wójtowicz, Michael Leitner

Faculty Publications

Progress in surveillance technology has led to the development of Closed-Circuit Television (CCTV) systems in cities around the world. Cameras are considered instrumental in crime reduction, yet existing research does not unambiguously answer the question whether installing them affects the number of crimes committed. The quasi-experimental method usually applied to evaluate CCTV systems’ effectiveness faces difficulties with data quantity and quality. Data quantity has a bearing on the number of crimes that can be conclusively inferred using the experimental procedure. Data quality affects the level of crime data aggregation. The lack of the exact location of a crime incident in …

Macromolecular-Clustered Facial Amphiphilic Antimicrobials, Md Anisur Rahman, Marpe Bam, Edgar Luat, Moumita Sharmin Jui, Mitra S. Ganewatta, Tinom Shokfai, Mitzi Nagarkatti, Alan W. Decho

Faculty Publications

Bacterial infections and antibiotic resistance, particularly by Gram-negative pathogens, have become a global healthcare crisis. We report the design of a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requiring a globally conformational arrangement associated with highly unfavorable entropic loss. This concept of macromolecular architectures is demonstrated with a series of multicyclic natural product-based cationic polymers. We have shown that cholic acid derivatives with three charged head groups are more potent and selective than lithocholic and deoxycholic counterparts, particularly against Gram-negative bacteria. This is ascribed to the formation …

Mammal Collections Of The Western Hemisphere: A Survey And Directory Of Collections, Jonathan L. Dunnum, Bryan S. Mclean, Robert C. Dowler, Sergio Ticul Alvarez-Castañeda, Jeff E. Bradley, Robert D. Bradley, Leslie N. Carraway, Juan P. Carrera-E, Christopher J. Conroy, Brandi S. Coyner, John R. Demboski, Carl W. Dick, Kate Doyle, Jacob A. Esselstyn, Eliecer Gutiérrez, John D. Hanson, Paula M. Holahan, Thorvald Holmes, Carlos A. Iudica, Rafael N. Leite, Thomas E. Lee, Burton K. Lim, Jason L. Malaney, Suzanne B. Mclaren, Nancy D. Moncrief, Link Olson, Nicte Ordóñez-Garza, Caleb D. Phillips, Marcia A. Revelez, Eric A. Rickart, Duke S. Rogers, Cody W. Thompson, Nathan S. Upham

Faculty Publications

As a periodic assessment of the mammal collection resource, the Systematic Collections Committee (SCC) of the American Society of Mammalogists undertakes decadal surveys of the collections held in the Western Hemisphere. The SCC surveyed 429 collections and compiled a directory of 395 active collections containing 5,275,155 catalogued specimens. Over the past decade, 43 collections have been lost or transferred and 38 new or unsurveyed collections were added. Growth in number of total specimens, expansion of genomic resource collections, and substantial gains in digitization and web accessibility were documented, as well as slight shifts in proportional representation of taxonomic groups owing …

Timeless, Not Temporal, Hyveth Williams

Faculty Publications

No abstract provided.

Gauging Support For Macroecological Patterns In Helminth Parasites, Tad A. Dallas, A. Alonso Aguirre, Sarah Budischak, Colin Carlson, Vanessa Ezenwa, Barbara Han, Shan Huang, Patrick R. Stephens

Faculty Publications

© 2018 John Wiley & Sons Ltd Aim: To explore spatial patterns of helminth parasite diversity, and to investigate three main macroecological patterns – (a) latitude–diversity relationships, (b) positive scaling between parasite and host diversity, and (c) species–area relationships – using a largely underutilized global database of helminth parasite occurrence records. Location: Global. Methods: We examined the London Natural History Museum’s collection of helminth parasite occurrence records, consisting of over 18,000 unique host species and 27,000 unique helminth parasite species distributed across over 350 distinct terrestrial and aquatic localities. Results: We find support for latitudinal gradients in parasite diversity and …

Recovery Of Horse Fly Populations In Louisiana Marshes Following The Deepwater Horizon Oil Spill, Claudia Husseneder, Jong Seok Park, Lane D. Foil

Faculty Publications

© 2018, The Author(s). The Deepwater Horizon oil spill in April 2010 had unprecedented impact on the Gulf of Mexico. We established the greenhead horse fly (Tabanus nigrovittatus Macquart) as a bioindicator of marsh health. This species is bound to coastal marshes, since its larvae develop as top invertebrate predators in the marsh soil. Immediately after the oil spill (2010–2011), populations of this horse fly declined in oiled areas of Louisiana marshes with significant impacts on genetic structure. In this follow-up study five years after the catastrophic event (2015–2016), we now report signs of recovery of populations in formerly oiled …

Type I Interferon Potentiates Iga Immunity To Respiratory Syncytial Virus Infection During Infancy, Diego R. Hijano, David T. Siefker, Bishwas Shrestha, Sridhar Jaligama, Luan D. Vu, Heather Tillman, David Finkelstein, Jordy Saravia, Dahui You, Stephania A. Cormier

Faculty Publications

© 2018, The Author(s). Respiratory syncytial virus (RSV) infection is the most frequent cause of hospitalization in infants and young children worldwide. Although mucosal RSV vaccines can reduce RSV disease burden, little is known about mucosal immune response capabilities in children. Neonatal or adult mice were infected with RSV; a subset of neonatal mice received interferon alpha (IFN-α) (intranasal) prior to RSV infection. B cells, B cell activating factor (BAFF) and IgA were measured by flow cytometry. RSV specific IgA was measured in nasal washes. Nasal associated lymphoid tissue (NALT) and lungs were stained for BAFF and IgA. Herein, we …

Bloodstream Infection Due To Piperacillin/Tazobactam Non-Susceptible, Cephalosporin Susceptible Escherichia Coli: A Missed Opportunity For De-Escalation Of Therapy, Leah Carlisle, Julie Ann Justo, Majdi N. Al-Hasan

Faculty Publications

An increasing number of reports describing Escherichia coli isolates with piperacillin/tazobactam resistance, despite retained cephalosporin susceptibility, suggest further emergence of this phenotypic resistance pattern. In this report, a patient with metastatic breast cancer presented to medical care after two days of chills, nausea, vomiting, reduced oral intake, and generalized weakness. Blood and urine cultures grew E. coli as identified by rapid diagnostics multiplex PCR and MALDI-TOF, respectively. The patient continued to manifest signs of sepsis with hypotension and tachypnea during the first three days of hospitalization despite empirical antimicrobial therapy with intravenous piperacillin/tazobactam. After in vitro antimicrobial susceptibility testing demonstrated …

Limitations In Predicting The Space Radiation Health Risk For Exploration Astronauts, Jeffery C. Chancellor, Rebecca S. Blue, Keith A. Cengel, Serena M. Auñón-Chancellor, Kathleen H. Rubins, Helmut G. Katzgraber, Ann R. Kennedy

Faculty Publications

Despite years of research, understanding of the space radiation environment and the risk it poses to long-duration astronauts remains limited. There is a disparity between research results and observed empirical effects seen in human astronaut crews, likely due to the numerous factors that limit terrestrial simulation of the complex space environment and extrapolation of human clinical consequences from varied animal models. Given the intended future of human spaceflight, with efforts now to rapidly expand capabilities for human missions to the moon and Mars, there is a pressing need to improve upon the understanding of the space radiation risk, predict likely …