Digital Commons Network^™

Highlights From The American Heart Association's Epi|Lifestyle 2019 Scientific Sessions, Alvaro Alonso, Madison D. Anderson, Michael P. Bancks, Sherry Ann Brown, Melissa C. Caughey, Alex R. Chang, Erin Delker, Kathryn Foti, Véronique Gingras, Michael G. Nanna, Alexander C. Razavi, Jewel Scott Phd, Rn, Fnp-C, Elizabeth Selvin, Catherine Tcheandjieu, Alvin G. Thomas, Ruth Alma N. Turkson-Ocran, Allison Webel, Deborah R. Young, Bailey M. Debarmore

Faculty Publications

No abstract provided.

Using Big Data Analytics To Improve Hiv Medical Care Utilisation In South Carolina: A Study Protocol, Bankole Olatosi, Jiajia Zhang, Sharon Weissman, Jianjun Hu, Mohammad Rifat Haider, Xiaoming Li

Faculty Publications

Introduction Linkage and retention in HIV medical care remains problematic in the USA. Extensive health utilisation data collection through electronic health records (EHR) and claims data represent new opportunities for scientific discovery. Big data science (BDS) is a powerful tool for investigating HIV care utilisation patterns. The South Carolina (SC) office of Revenue and Fiscal Affairs (RFA) data warehouse captures individual-level longitudinal health utilisation data for persons living with HIV (PLWH). The data warehouse includes EHR, claims and data from private institutions, housing, prisons, mental health, Medicare, Medicaid, State Health Plan and the department of health and human services. The …

"You Can't Go Back To Holding Hands." Reading Judy Blume's Forever In The #Metoo Era, Jenna Spiering, Kate Kedley

Faculty Publications

Judy Blume’s Forever is a cultural artifact that gives readers a historical look at society’s attitudes about sex and sexuality at the time of publication in 1975. However, in the #MeToo era, Blume’s text is poised for new analysis in light of important conversations and concerns about sex, sexuality, and consent. In this article, Critical Youth Studies and Queer Theory are used to explore the ways in which young readers can critically engage with Blume’s novel and questions about virginity, sex, sexuality, and consent associated with the #MeToo movement.

An Interdisciplinary Weight Loss Program Improves Body Composition And Metabolic Profile In Adolescents With Obesity: Associations With The Dietary Inflammatory Index, Yasmin Alaby Martins Ferreira, Ana Claudia Pelissari Kravchychyn, Sofia De Castro Ferreira Vicente, Raquel Munhoz Da Silveira Campos, Lian Tock, Lila Missae Oyama, Valter Tadeu Boldarine, Deborah Cristina Landi Masquio, David Thivel, Nitin Shivappa, James R. Hébert, Ana R. Dâmaso

Faculty Publications

Background and Aims: The prevalence of overweight and obesity consitutes a global epidemic and it is growing around the world. Food and nutrition are essential requirements for promoting health and protecting against non-communicable chronic diseases, such as obesity and cardiovascular disease. Specific dietary components may modulate inflammation and oxidative stress in obese individuals. The Dietary Inflammatory Index (DII®) was developed to characterize the anti- and pro-inflammatory effects of individuals' diet. Few studies have investigated the role of diet-associated inflammation in adolescents with obesity. The present study aims to investigate the effects of an interdisciplinary weight loss therapy on DII scores …

Occupational Noise Dose Reduction Via Behavior Modification Using In-Ear Dosimetry Among United States Air Force Personnel Exposed To Continuous And Impulse Noise, Jesse Trawick, Jeremy M. Slagley, Robert Eninger

Faculty Publications

In-ear dosimetry and noise exposure feedback were used to modify worker attitude and behavior regarding hearing protection use. The study specifically addressed whether providing in-ear noise exposure data to workers resulted in a reduction in average noise dose rate equivalent continuous levels. Nineteen combat arms instructors (impulse noise group) and heavy equipment operators (continuous noise group) working for the United States Air Force volunteered to participate in a six-month field study using in-ear dosimeters to collect daily noise level data. Participants served as their own control group, receiving periodic noise exposure feedback reports in the latter half of the study …

Cellular Effects Of Butyrate On Vascular Smooth Muscle Cells Are Mediated Through Disparate Actions On Dual Targets, Histone Deacetylase (Hdac) Activity And Pi3k/Akt Signaling Network, Omana P. Mathew, Kasturi Ranganna, Joseph Mathew, Meiling Zhu, Zivar Yousefipour, Chelliah Selvam, Shirlette G. Milton

Faculty Publications

Vascular remodeling is a characteristic feature of cardiovascular diseases. Altered cellular processes of vascular smooth muscle cells (VSMCs) is a crucial component in vascular remodeling. Histone deacetylase inhibitor (HDACI), butyrate, arrests VSMC proliferation and promotes cell growth. The objective of the study is to determine the mechanism of butyrate-induced VSMC growth. Using proliferating VSMCs exposed to 5 mM butyrate, immunoblotting studies are performed to determine whether PI3K/Akt pathway that regulates different cellular effects is a target of butyrate-induced VSMC growth. Butyrate inhibits phosphorylation-dependent activation of PI3K, PDK1, and Akt, eliciting differential effects on downstream targets of Akt. Along with previously …

Curriculum Infusion Through Case Studies: Engaging Undergraduate Students In Course Subject Material And Influencing Behavior Change, Ellen J. Bass, Holly A. Foster, Douglas W. Lee, Susan E. Bruce, Reid Bailey

Faculty Publications

This study investigated infusing health promotion topics into an engineering course via problem-based case studies and lecture to assess student learning and self-reported behavior. Junior-level systems engineering students in two sections participated: one section with 52 students and one with 36. One section received a celebratory drinking case; one received distracted driving case and a lecture about hazardous drinking. Student ability ratings related to the course subject matter generally improved with both cases. The lecture appeared to enhance health promotion knowledge. Students self-reported behavior change with both cases. Case studies as a form of curriculum infusion for health promotion topics …

The Respiratory Burst Oxidase Homolog D (Rbohd) Cell And Tissue Distribution In Potato-Potato Virus Y (Pvyntn) Hypersensitive And Susceptible Reactions, Rodrigo A. Valverde

Faculty Publications

The respiratory burst oxidase homolog D (RbohD) acts as a central driving force of reactive oxygen species signaling in plant cells by integrating many different signal transduction pathways in plants, including incompatible interactions with pathogens. This study demonstrated the localization and distribution of RbohD in two types of potato-potato virus Y (PVY) interactions: Compatible and incompatible (resistant). The results indicated a statistically significant induction of the RbohD antigen signal in both interaction types. In the hypersensitive response (resistant reaction) of potato with a high level of resistance to the potato tuber necrotic strain of PVY (PVYNTN), RbohD localization followed by …

Evidence For Pathways Of Concentrated Submarine Groundwater Discharge In East Antarctica From Helicopter-Borne Electrical Resistivity Measurements, Neil Foley, Slawek M. Tulaczyk, Denys Grombacher, Peter T. Doran, Jill Mikucki, Krista F. Myers, Nikolaj Foged, Hilary Dugan, Esben Auken, Ross Virginia

Faculty Publications

© 2019 by the authors. The Southern Ocean receives limited liquid surface water input from the Antarctic continent. It has been speculated, however, that significant liquid water may flow from beneath the Antarctic Ice Sheet, and that this subglacial flow carries that water along with dissolved nutrients to the coast. The delivery of solutes, particularly limiting nutrients like bioavailable iron, to the Southern Ocean may contribute to ecosystem processes including primary productivity. Using a helicopter-borne time domain electromagnetic survey along the coastal margins of the McMurdo Dry Valleys region of Southern Victoria Land, Antarctica, we detected subsurface connections between inland …

The Expression Of Adipose Tissue-Derived Cardiotrophin-1 In Humans With Obesity, Jacqueline Stephens, Eric Ravussin, Ursula White

Faculty Publications

© 2019, MDPI AG. All rights reserved. Cardiotrophin-1 (CT-1) is a gp130 cytokine that was previously characterized for its e ects on cardiomyocytes and identified as a marker of heart failure. More recent studies reported elevated circulating levels of CT-1 in humans with obesity and metabolic syndrome (MetS). However, a subsequent rodent study implicated CT-1 as a potential therapeutic target for obesity and MetS. Adipose tissue (AT) is broadly acknowledged as an endocrine organ and is a substantial source of CT-1. However, no study has examined the expression of adipose-derived CT-1 in humans. We present the first analysis of CT-1 …

Meta-Analysis Of Yield Response Of Foliar Fungicide-Treated Hybrid Corn In The United States And Ontario, Canada, Kiersten A. Wise, Damon Smith, Anna Freije, Daren S. Mueller, Yuba Kandel, Tom Allen, Carl A. Bradley, Emmanuel Byamukama, Martin Chilvers, Travis Faske, Andrew Friskop, Clayton Hollier, Tamra A. Jackson-Ziems, Heather Kelly, Bob Kemerait, Paul Price, Alison Robertson, Albert Tenuta

Faculty Publications

Background Foliar fungicide applications to corn (Zea mays L.) occur at one or more application timings ranging from early vegetative growth stages to mid-reproductive stages. Previous studies indicated that fungicide applications are profitable under high disease pressure when applied during the tasseling to silking growth stages. Few comprehensive studies in corn have examined the impact of fungicide applications at an early vegetative growth stage (V6) compared to late application timings (VT) for yield response and return on fungicide investment (ROI) across multiple locations. Objective Compare yield response of fungicide application timing across multiple fungicide classes and calculate the probability of …

Field Efficacy Of Insect Pathogen, Botanical, And Jasmonic Acid For The Management Of Wheat Midge Sitodiplosis Mosellana And The Impact On Adult Parasitoid Macroglenes Penetrans Populations In Spring Wheat, Govinda Shrestha, Gadi V.P. Reddy

Faculty Publications

The wheat midge, Sitodiplosis mosellana, is a serious pest of wheat worldwide. In North America, management of S. mosellana in spring wheat relies on the timely application of pesticides, based on midge adults levels caught in pheromone traps or seen via field scouting during wheat heading. In this context, biopesticides can be an effective alternative to pesticides for controlling S. mosellana within an Integrated Pest Management program. A field study using insect pathogenic fungus Beauveria bassiana GHA, nematode Steinernema feltiae with Barricade polymer gel 1%, pyrethrin, combined formulations of B. bassiana GHA and pyrethrin, Jasmonic acid (JA) and chlorpyrifos (chemical …

Fluid Restriction Decreases Solid Food Consumption Post-Exercise, Cristian Pérez-Luco, Francisco Díaz-Castro, Carlos Jorquera, Rodrigo Troncoso, Hermann Zbinden-Foncea, Neil M. Johannsen, Mauricio Castro-Sepulveda

Faculty Publications

Dehydration in rodents induces anorexia. In humans however, the role of dehydration in energy intake is controversial. This study investigated the effect of extreme fluid restriction on acute energy intake during and after exercise-induced dehydration. Eight physically active participants performed two exercise sessions to induce dehydration. After the exercise, the men were allowed to either rehydrate for 2 h or were maintained in a hypohydrated state, in a randomized manner. After 2 h, they were given cereal bars ad libitum for 1 h. Blood and saliva samples of the participants were collected before the exercise session, after the exercise session, …

Efficacy And Safety Of A Combination Of Selamectin Plus Sarolaner For The Treatment And Prevention Of Flea Infestations And The Treatment Of Ear Mites In Cats Presented As Veterinary Patients In The United States, Adriano F. Vatta, Melanie R. Myers, Jady J. Rugg, Sara Chapin, Aleah Pullins, Vickie L. King, Douglas Rugg

Faculty Publications

Two randomised, single-masked, multi-center field studies were conducted in the United States in cats presented as veterinary patients. The first study evaluated the efficacy and safety of a topically applied formulation of selamectin plus sarolaner (Revolution® Plus/Stronghold® Plus, Zoetis) against natural flea infestations; the second study evaluated its efficacy against natural ear mite infestations. The product was administered topically by the cats’ owners at the dose range provided in the market product of 6.0–12.0 mg selamectin and 1.0–2.0 mg sarolaner per kg bodyweight. Imidacloprid plus moxidectin (Advantage® Multi for Cats, Bayer) was used as a positive control in both studies …

Expenditure, Coping, And Academic Behaviors Among Food-Insecure College Students At 10 Higher Education Institutes In The Appalachian And Southeastern Regions, Rebecca L. Hagedorn, Laura H. Mcarthur, Lanae B. Hood, Maureen Berner, Elizabeth T. Anderson Steeves, Carol L. Connell, Elizabeth Wall-Bassett, Marsha Spence, Oyinlola Toyin Babatunde, E. Brooke Kelly, Julia F. Waity, J. Porter Lillis, Melissa D. Olfert

Faculty Publications

Background

A number of studies have measured college student food insecurity prevalence higher than the national average; however, no multicampus regional study among students at 4-y institutions has been undertaken in the Appalachian and Southeast regions of the United States. Objectives

The aims of this study were to determine the prevalence of food insecurity among college students in the Appalachian and Southeastern regions of the United States, and to determine the association between food-insecurity status and money expenditures, coping strategies, and academic performance among a regional sample of college students. Methods

This regional, cross-sectional, online survey study included 13,642 college …

Current Status And Recommendations Toward A Virus Standard For Ballast Water, Yiseul Kim, Samuel D. Snow, Vanessa Reichel-Deland, Mostafa Maghsoodi, Gabrielle M. Langlois, Volodymyr V. Tarabara, Joan B. Rose

Faculty Publications

Ballast water contains and transfers a variety of biological and non-biological materials between biomes. This study aimed to summarize published literature on the viruses found in ballast water, to evaluate ultrafiltration and plaque assay as methods for concentrating and enumerating viruses, and to assess the efficacy of UV irradiation in the inactivation of infectious viruses in ballast water. Previous studies reported high virus concentrations in ballast tanks, ranging from 109 to 1014 viral particles/L. The ultrafiltration and plaque assay were efficient in concentrating and enumerating four types of phages: MS2, PhiX174, P22, and PP7. The UV dose (radiant fluence) necessary …

Predicting Climate Types For The Continental United States Using Unsupervised Clustering Techniques, D. Sathiaraj, X. Huang, J. Chen

Faculty Publications

The problem of clustering climate data observation sites and grouping them by their climate types is considered. Machine learning–based clustering algorithms are used in analyzing climate data time series from more than 3,000 climate observation sites in the United States, with the objective of classifying climate type for regions across the United States. Understanding the climate type of a region has applications in public health, environment, actuarial science, insurance, agriculture, and engineering. In this study, daily climate data measurements for temperature and precipitation from the time period 1946–2015 have been used. The daily data observations were grouped into three derived …

The Supreme Court's Legitimacy Dilemma, Tara Leigh Grove

Faculty Publications

No abstract provided.

Successful Weight Loss Initiation And Maintenance Among Adolescents With Overweight And Obesity: Does Age Matter?, Diana Rancourt, Chad D. Jensen, Kara Mcrae Duraccio, E. Whitney Evans, Rena R. Wing, Elissa Jelalian

Faculty Publications

Background—Treatments for adolescents with overweight/obesity demonstrate mixed success, which may be due to a lack of consideration for developmental changes during this period. Potential developmental differences in weight loss motivations, weight maintenance behaviors, and the role of parents in these efforts were examined in a sample of successful adolescent weight losers.

Methods—Participants enrolled in the Adolescent Weight Control Registry (n = 49) self-reported demographic information and weight history, reasons for weight loss and weight control, weight loss approach and weight maintenance strategies, and perceived parental involvement with weight loss. Associations between age at weight loss initiation and the aforementioned factors …

Marital Satisfaction Amongst Nigerian Immigrants In North America (Nina): Pilot Study, Jochebed B. Ade-Oshifogun, Joan Aina, Augusta Y. Olaore

Faculty Publications

Background: It has been observed that some Nigerian Families that immigrated to North America (NINA) seem to have very stressful marital relationships that lead to separation or divorce. The goal of this study was to determine the level of marital satisfaction among NINA

Method: A simple, standardized survey tool was utilized to measure the index of marital satisfaction (IMS). The score varied from 0-100 with a lower score (<30 >points) indicating marital satisfaction. A demographic questionnaire was also administered to the subjects. Descriptive data analysis and level of marital satisfaction were computed in SPSS (version 25).

Results: Forty-five of the …

Use Of Alcohol: Not Safe At Any Level, Alina M. Baltazar

Faculty Publications

The safest level of alcohol consumpton is zero. Alcohol is not a health beverage! Drinking while in college is risking your chances of success in school as well as your future health and happiness.

The Joy Of The Lord Is Your Strength, Gerald A. Klingbeil

Faculty Publications

No abstract provided.

International Comparison Of The Levels And Potential Correlates Of Objectively Measured Sedentary Time And Physical Activity Among Three-To-Four-Year-Old Children, Kaiseree I. Dias, James White, Russell Jago, Greet Cardon, Rachel Davey, Kathleen F. Janz, Russell R. Pate, Jardena J. Puder, John J. Reilly, Ruth Kipping

Faculty Publications

Physical activity (PA) patterns track from childhood through to adulthood. The study aimed to determine the levels and correlates of sedentary time (ST), total PA (TPA), and moderate-to-vigorous PA (MVPA) in preschool-aged children. We conducted cross-sectional analyses of 1052 children aged three-to-four-years-old from six studies included in the International Children’s Accelerometry Database. Multilevel linear regression models adjusting for age, gender, season, minutes of wear time, and study clustering effects were used to estimate associations between age, gender, country, season, ethnicity, parental education, day of the week, time of sunrise, time of sunset, and hours of daylight and the daily minutes …

Exploratory Qualitative Study To Understand The Underlying Motivations And Strategies Of The Private For-Profit Healthcare Sector In Urban Bangladesh, Alayne Mary Adams, Rushdia Ahmed, Tanzir Ahmed Shuvo, Sifat Shahana Yusuf, Sadika Akhter, Iqbal Anwar

Faculty Publications

Objectives This paper explores the underlying motivations and strategies of formal small and medium-sized formal private for-profit sector hospitals and clinics in urban Bangladesh and their implications for quality and access.

Methods This exploratory qualitative study was conducted in Dhaka, Sylhet and Khulna City Corporations. Data collection methods included key informant interviews (20) with government and private sector leaders, in-depth interviews (30) with clinic owners, managers and providers and exit interviews (30) with healthcare clients.

Results Profit generation is a driving force behind entry into the private healthcare business and the provision of services. However, non-financial motivations are also emphasised …

Adiposity Mediates The Association Between The Dietary Inflammatory Index And Markers Of Type 2 Diabetes Risk In Middle-Aged Black South African Women, Asanda Mtintsilana, Lisa K. Micklesfield, Elin Chorell, Tommy Olsson, Nitin Shivappa, James R. Hebert, Andre P. Kengne, Julia H. Goedecke

Faculty Publications

The dietary inflammatory index (DII^®), a validated tool used to measure the inflammatory potential of the diet, has been associated with metabolic disorders in various settings, but not in African populations. The aim of this study was to investigate whether the DII is associated with markers of type 2 diabetes (T2D) risk, and if this association is mediated by adiposity and/or low-grade inflammation, in black South Africa women. Energy-adjusted-DII (E-DII) scores were calculated in 190 women (median age, 53 years) from the Birth-to-Twenty plus cohort using a validated food frequency questionnaire. Fasting glucose, insulin, HbA1c, and inflammatory cytokines …

Profiles Of Religiousness, Spirituality, And Psychological Adjustment In Emerging Adults, Carolyn Mcnamara Barry, Jennifer L. Christofferson, Eric P. Boorman, Larry J. Nelson

Faculty Publications

Although emerging adults are engaged in heightened levels of meaning-making (Barry and Abo-Zena (eds) in Emerging adults’ religiousness and spirituality: meaning-making in an age of transition. Oxford University Press, New York, 2014), research has focused on either religiousness or spirituality (R/S) in each study. While R/S individually have been associated with emerging adults’ psychological adjustment (Rew and Wong in J Adolesc Health 38:433–442, 2006), scholars have rarely explored the specific profiles of R/S adjustment. Thus, a diverse group of undergraduate students (N = 792; Mage = 19.61, SD= 1.86; 69% women) completed questionnaires online involving these constructs. Preliminary …

Challenges For Natural Hydrogels In Tissue Engineering, Esmaiel Jabbari

Faculty Publications

Protein-based biopolymers derived from natural tissues possess a hierarchical structure in their native state. Strongly solvating, reducing and stabilizing agents, as well as heat, pressure, and enzymes are used to isolate protein-based biopolymers from their natural tissue, solubilize them in aqueous solution and convert them into injectable or preformed hydrogels for applications in tissue engineering and regenerative medicine. This review aims to highlight the need to investigate the nano-/micro-structure of hydrogels derived from the extracellular matrix proteins of natural tissues. Future work should focus on identifying the nature of secondary, tertiary, and higher order structure formation in protein-based hydrogels derived …

Challenges For Natural Hydrogels In Tissue Engineering, Esmaiel Jabbari

Faculty Publications

Protein-based biopolymers derived from natural tissues possess a hierarchical structure in their native state. Strongly solvating, reducing and stabilizing agents, as well as heat, pressure, and enzymes are used to isolate protein-based biopolymers from their natural tissue, solubilize them in aqueous solution and convert them into injectable or preformed hydrogels for applications in tissue engineering and regenerative medicine. This review aims to highlight the need to investigate the nano-/micro-structure of hydrogels derived from the extracellular matrix proteins of natural tissues. Future work should focus on identifying the nature of secondary, tertiary, and higher order structure formation in protein-based hydrogels derived …

Female Family Members Lack Understanding Of Indeterminate Negative Brca1/2 Test Results Shared By Probands, Deborah Himes, Deborah K. Gibbons, Wendy C. Birmingham, Renea L. Beckstrand, Amanda Gammon, Anita Y. Kinney, Margaret F. Clayton

Faculty Publications

Genetic test results have important implications for close family members. Indeterminate negative results are the most common outcome of BRCA1/2 mutation testing. Little is known about family members’ understanding of indeterminate negative BRCA1/2 test results. The purpose of this mixed-methods study was to investigate how daughters and sisters received and understood genetic test results as shared by their mothers or sisters. Participants included 81 women aged 40-74 with mothers or sisters previously diagnosed with breast cancer and who received indeterminate negative BRCA1/2 test results. Participants had never been diagnosed with breast cancer nor received their own genetic testing or counseling. …

Dietary Inflammatory Index And Odds Of Colorectal Cancer And Colorectal Adenomatous Polyps In A Case-Control Study From Iran, Pegah Rafiee, Nitin Shivappa, James R. Hébert, Saeede Jaafari Nasab, Alireza Bahrami, Azita Hekmatdoost, Bahram Rashidkhani, Amir Sadeghi, Mohammad Houshyari, Ehsan Hejazi

Faculty Publications

Background: Chronic inflammation is implicated in the development of colorectal cancer (CRC) and its precursor; colorectal adenomatous polyps (CAP). Some dietary factors are important triggers for systemic inflammation. Therefore, the present study aimed to investigate the association between the dietary inflammatory index (DII^®) and the risk of CRC and CAP in an Iranian case-control study. Methods: 134 newly diagnosed CRC patients, 130 newly diagnosed CAP patients, and 240 hospitalized controls were recruited using convenience sampling. Energy-adjusted DII (E-DII) scores were computed based on dietary intake assessed using a reproducible and valid 148-item food frequency questionnaire. Logistic regression models …