Digital Commons Network^™

Do You Feel In Control? Sexual Desire, Sexual Passion Expression, And Associations With Perceived Compulsivity To Pornography And Pornography Use Frequency, Nathan D. Leonhardt, Dean M. Busby, Brian J. Willoughby

Faculty Publications

Previous scholars have found that when individuals feel that pornography use is uncontrollable, it is linked to more extreme negative outcomes than frequency of use. With a Mechanical Turk sample of 1421 individuals, we used structural equation modeling to evaluate how multiple aspects of sexual desire (sexual drive and dyadic desire) and multiple aspects of sexual passion expression (harmonious, obsessive, and inhibited) were associated with both pornography use frequency and perceived compulsivity to pornography. In general, sexual desire was more connected to pornography use and sexual passion was more connected to perceived compulsivity. Specifically, sexual drive was associated with higher …

Lipocalin 2 Induces Neuroinflammation And Blood-Brain Barrier Dysfunction Through Liver-Brain Axis In Murine Model Of Nonalcoholic Steatohepatitis, Ayan Mondal, Dipro Bose, Punnag Saha, Sutapa Sarkar, Ratanesh K. Seth, Diana Kimono, Muayad Albadrani, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterjee

Faculty Publications

BACKGROUND:

Recent clinical and basic research implicated a strong correlation between NAFLD/NASH phenotypes with ectopic manifestations including neuroinflammation and neurodegeneration, but the mediators and critical pathways involved are not well understood. Lipocalin 2 (Lcn2) is one of the important mediators exclusively produced in the liver and circulation during NASH pathology.

METHODS:

Using murine model of NASH, we studied the role of Lcn2 as a potent mediator of neuroinflammation and neurodegeneration in NASH pathology via the liver-brain axis. RESULTS: Results showed that high circulatory Lcn2 activated 24p3R (Lipocalin2 receptor) in the brain and induced the release of high mobility group box …

Terrorism And Right-Wing Extremism: History And Comparative Definitions, Kwame B. Antwi-Boasiako, Caleb Grant Hill

Faculty Publications

Recent narratives on terrorism have focused on the definitions. Terrorism is not a new phenomenon, but the problem resides in its definition and who is defining it. Conceptualizing terrorism depends on which framework one utilizes. The use of different lenses to define the term has contributed to the lack of global acceptance of what constitutes terrorism, hence the difficulty of gathering data for analysis. It is also a conundrum when powerful nations legitimize their terrorist activities against weaker ones. This, unfortunately, has led to the subjectiveness of every attempt in the literature to objectively provide a globally acceptable definition. Using …

A Letter To Reconsider The Conditions For Testing Decontaminated N95 Respirators For Emergency Reuse To Address Shortage, Eric P. Vejerano, Jeonghyeon Ahn

Faculty Publications

The battle with COVID-19 pandemic has resulted in the shortage of personal protective equipment, particularly, N95 respirators. Healthcare workers who reused N95 respirators may resort to unproven methods of cleaning/sterilization that can severely compromise the respirators’ filtration efficiency. A recently issued guideline will test decontaminated N95 respirators against particles with a median diameter of 0.075 ± 0.020 µm at a flow rate of 85 L min–1. For emergency reuse, these conditions may be too stringent. N95 respirators tested at this flow rate had predicted efficiencies of < 69%, assuming complete degradation of their electrostatic coating. Experimental efficiencies were ~15% lower. For emergency reuse, we recommend to either adjust the flow rate closer to normal breathing, or the size of the test particle should reflect that of virus-laden respiratory aerosols (~> 0.5 µm). By reconsidering the test conditions, a substantial fraction of used/decontaminated respirators can …

Post-Traumatic Stress And Marijuana Outcomes: The Mediating Role Of Marijuana Protective Behavioral Strategies, Hallie R. Jordan, Michael B. Madson, Adrian J. Bravo, Matthew R. Pearson

Faculty Publications

Background: The present study investigated the mediating role of protective behavioral strategies for marijuana (PBSM) on the relationship between posttraumatic stress disorder (PTSD) and marijuana outcomes (i.e. marijuana use frequency, marijuana use quantity, cannabis use disorder (CUD) symptoms, and marijuana-related problems).

Methods: Participants were 1,107 traditional age college students (M_age = 20.26, SD = 3.32; 66.5% White, non-Hispanic; 68.8% female), who reported consuming marijuana at least once in the last 30 days and completed measures of PTSD symptoms, PBSM, and marijuana-related outcomes.

Results: PBSM significantly mediated the positive relationships between PTSD symptoms and both CUD symptoms and marijuana-related …

Highlights Of Clinical Practice Guideline For The Management Of Community-Acquired Pneumonia: 2019 Update By The American Thoracic Society And Infectious Diseases Society Of America, Hongmei Wang, Molly Brong, Shirley Pham, Diane Dreucean

Faculty Publications

Pneumonia is the leading cause of morbidity and mortality in the United States. The American Thoracic Society and The Infectious Diseases Society of America recently published updated guidelines for the diagnosis and treatment of community-acquired pneumonia. Initial antibiotic therapy should cover for Streptococcus pneumoniae, Haemophilus influenzae, and other gram-negative bacilli. Patients who have risk factors for the development of antibiotic resistant pathogens, such as methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa should have appropriate empiric coverage for these pathogens. The recommended duration of treatment of community-acquired pneumonia is a minimum of 5 days in conjunction with clinical improvement, which has remained …

Greenwashing No More: The Case For Stronger Regulation Of Environmental Marketing, Robin M. Rotman, Chloe J. Gossett, Hope D. Goldman

Faculty Publications

Fraudulent and deceptive environmental claims in marketing (sometimes called “greenwashing”) are a persistent problem in the United States, despite nearly thirty years of efforts by the Federal Trade Commission (FTC) to prevent it. This Essay focuses on a recent trend in greenwashing - fraudulent “organic” claims for nonagricultural products, such as home goods and personal care products. We offer three recommendations. First, we suggest ways that the FTC can strengthen its oversight of “organic” claims for nonagricultural products and improve coordination with the USDA. Second, we argue for inclusion of guidelines for “organic” claims in the next revision of the …

Dynamic Glucose Disposal Is Driven By Reduced Endogenous Glucose Production In Response To Voluntary Wheel Running: A Stable Isotope Approach, Timothy D. Allerton, Greg M. Kowalski, Hardy Hang, Jacqueline Stephens

Faculty Publications

© 2020 the American Physiological Society. Dynamic glucose disposal is driven by reduced endogenous glucose production in response to voluntary wheel running: A stable isotope approach. Am J Physiol Endocrinol Metab 319: E2-E10, 2020. First published April 28, 2020; doi:10.1152/ajpendo.00450.2019.-To resolve both the systems level and molecular mechanisms responsible for exerciseinduced improvements in glucose tolerance, we sought to test the effect of voluntary wheel running exercise on postprandial glucose dynamics. We utilized a stable isotope-labeled oral glucose tolerance test (SI-OGTT) incorporating complementary deuterium glucose tracers at a 1:1 ratio (2-2H-glucose and 6-6 2H-glucose; 2g/kg lean body mass) to distinguish between …

Covid-19 Diagnostic Process In Mainland China: The Math Beyond Pneumonia, Feng Wu, Weishan Huang

Faculty Publications

No abstract provided.

Comparison Of Chemotherapeutic Activities Of Rhodamine-Based Gumbos And Nanogumbos, Nimisha Bhattarai, Mi Chen, Rocío L. Pérez, Sudhir Ravula, Robert M. Strongin, Karen Mcdonough, Isiah M. Warner

Faculty Publications

© 2020 by the authors. Rhodamine derivatives have been widely investigated for their mitochondrial targeting and chemotherapeutic properties that result from their lipophilic cationic structures. In previous research, we have found that conversion of Rhodamine 6G into nanoGUMBOS, i.e., nanomaterials derived from a group of uniform materials based on organic salts (GUMBOS), led to selective chemotherapeutic toxicity for cancer cells over normal cells. Herein, we investigate the chemotherapeutic activity of GUMBOS derived from four different rhodamine derivatives, two bearing an ester group, i.e., Rhodamine 123 (R123) and SNAFR-5, and two bearing a carboxylic acid group, i.e., rhodamine 110 (R110) and …

Adaptive Responses To Maternal Nutrient Restriction Alter Placental Transport In Ewes, Ashley K. Edwards, Sorin M. Mcknight, Katharine Askelson, Jason R. Mcknight, Kathrin A. Dunlap, M. Carey Satterfield

Faculty Publications

Introduction: Maternal nutrient partitioning, uteroplacental blood flow, transporter activity, and fetoplacental metabolism mediate nutrient delivery to the fetus. Inadequate availability or delivery of nutrients results in intrauterine growth restriction (IUGR), a leading cause of neonatal morbidity and mortality. Maternal nutrient restriction can result in IUGR, but only in an unforeseeable subset of individuals. Methods: To elucidate potential mechanisms regulating fetal nutrient availability, singleton sheep pregnancies were generated by embryo transfer. Pregnant ewes received either a 50% NRC (NR; n = 24) or 100% NRC (n = 7) diet from gestational Day 35 until necropsy on Day 125. Maternal weight did …

Mechanical Properties And Performance Under Laboratory And Field Conditions Of A Lightweight Fluorogypsum-Based Blend For Economic Artificial-Reef Construction, Yasser Bigdeli, Michele Barbato, Charles D. Lofton, Maria Teresa Gutierrez-Wing, Kelly A. Rusch

Faculty Publications

This paper investigates the mechanical properties under laboratory and field conditions of a concretelike blend made of fluorogypsum (FG), fly ash, and portland cement for artificial-reef construction, which is referred to as a FG-based blend. The 28-day compressive strength and relative volumetric expansion of the FG-based blend were statistically characterized. After 1 year of immersion in brackish water under field conditions, the compressive strength of the FG-based blend experienced a moderate reduction when compared with material under laboratory conditions but did not degrade below its 28-day value. Visual examination of the immersed specimens indicated that aquatic organisms are attracted to …

Effects Of Hurricane Harvey On The Trophic Status Of Juvenile Sport Fishes (Cynoscion Nebulosus, Sciaenops Ocellatus) In An Estuarine Nursery, Philip Matich, Kaya B. Moore, Jeffrey D. Plumlee

Faculty Publications

Understanding the implications of environmental disturbance is of growing importance as climate change and extreme weather events increasingly threaten estuaries and other coastal ecosystems. Among species at risk in estuarine habitats, sport fishes are of particular interest to conservation and management agencies, because of their ecological and economic value. Here, we evaluate the effects of Hurricane Harvey on the abundance, diet, and body condition of age-0 red drum (Sciaenops ocellatus) and spotted seatrout (Cynoscion nebulosus) in Powderhorn Lake, a nearshore estuary in Texas, USA. Catch data from seines indicated that the abundances of age-0 red drum and spotted seatrout were …

Fully Automated Pipeline For Body Composition Estimation From 3d Optical Scans Using Principal Component Analysis: A Shape Up Study, Sima Sobhiyeh, Nathan Borel, Marcelline Dechenaud, Clinten A. Graham, Michael Wong, Peter Wolenski, John Shepherd, Steven B. Heymsfield

Faculty Publications

The increasing prevalence and adaptability of 3D optical scan (3DO) technology has invoked many recent studies which use 3DO scanning as a convenient and inexpensive means for predicting body composition and health risks. The Shape Up studies seek a device-agnostic solution for body composition estimation based on principal component analysis (PCA). This paper reports a progress made on Shape Up's previous work which served as a criterion analysis for PCA-based body composition and health risk prediction. This study presents proof-of-concept for a novel automated landmark detection step that allows for a fully automated PCA-based approach to body composition estimation that …

Can Children Catch Up From The Consequences Of Undernourishment? Evidence From Child Linear Growth, Developmental Epigenetics, And Brain And Neurocognitive Development, Jef L. Leroy, Edward A. Frongillo Jr., Pragya Dewan, Maureen M. Black, Robert A. Waterland

Faculty Publications

Recovery from nutritionally induced height deficits continues to garner attention. The current literature on catch-up growth, however, has 2 important limitations: wide-ranging definitions of catch-up growth are used, and it remains unclear whether children can recover from the broader consequences of undernutrition. We addressed these shortcomings by reviewing the literature on the criteria for catch-up in linear growth and on the potential to recover from undernutrition early in life in 3 domains: linear growth, developmental epigenetics, and child brain and neurocognitive development. Four criteria must be met to demonstrate catch-up growth in height: after a period in which a growth-inhibiting …

Temporal And Stoichiometric Patterns Of Algal Stimulation Of Litter-Associated Heterotrophic Microbial Activity, Steven N. Francoeur, Robert K. Neely, Savannah Underwood, Kevin A. Kuehn

Faculty Publications

1. Periphyton communities associated with submerged plant detritus contain interacting autotrophic and heterotrophic microbes, and are sites of extracellular enzymatic activity. The strength and nature of these interactions might be expected to change over time as microbial communities develop on plant litter. Microbial interactions and enzymatic activity can be altered by nutrient availability, suggesting that litter stoichiometry could also affect these phenomena.
2. We grew wetland plants under ambient and nutrient‐enriched conditions to generate plant litter of differing nutrient content. In two experiments, we investigated: (1) the influence of algal photosynthesis on fungal and bacterial production and the activities of four extracellular …

The Combined Effect Of Exercise And Behavioral Therapy For Depression And Anxiety: Systematic Review And Meta−Analysis, Terence Moriarty, Kelsey C. Bourbeau, Akeisha Ayanniyi, Micah Zuhl

Faculty Publications

Behavioral therapy (BT) and exercise are efficacious treatments for depression and anxiety when employed separately. The combination of BT and exercise (BT+Ex) may augment improvements but the combined effect of these therapies is not fully elucidated. The purpose of this meta-analysis was to determine if BT+Ex yielded a significant reduction in depression and anxiety symptoms compared to BT alone (BT). Randomized controlled studies published prior to September 2019 were searched among several databases (PUBMED, MEDLINE, PsychArticle, and Cochrane Central Register of Clinical Trials). Studies that measured depression and anxiety symptoms following BT+Ex vs. BT were extracted and analyzed. The effect …

Toolkit Or Tinderbox? When Legal Systems Interface Conflict, Christie S. Warren

Faculty Publications

No abstract provided.

Family Behaviors As Unchanging Obstacles In End-Of-Life Care: 16-Year Comparative Data, Renea L. Beckstrand, Jasmine B. Jenkins, Karlen E. Luthy, Janelle L. B. Macintosh

Faculty Publications

Background Critical care nurses routinely care for dying patients. Research on obstacles in providing end-of-life care has been conducted for more than 20 years, but change in such obstacles over time has not been examined.

Objective To determine whether the magnitude scores of obstacles and helpful behaviors regarding end-of-life care have changed over time.

Methods In this cross-sectional survey study, questionnaires were sent to 2000 randomly selected members of the American Association of Critical-Care Nurses. Obstacle and helpful behavior items were analyzed using mean magnitude scores. Current data were compared with data gathered in 1999.

Results Of the 2000 questionnaires …

Relationships And Retaliation In The #Metoo Era, Nicole Buonocore Porter

Faculty Publications

In this #MeToo era, so much important work is being done (and so many stories are being told and listened to), but very little of the work focuses on retaliation. And none of the work focuses on situations where the fear of retaliation is not necessarily job loss (although that certainly happens) but rather, it is the fear of harming workplace relationships. This Article will use a real-life story of harassment to demonstrate how much workplace relationships matter-especially to women-and how the fear of harming those relationships often affects an employee's willingness to report harassment. Thus, this Article argues for …

“Library And Information Science” Literature In Web Of Science: What A Decade Tells Us About Scholarly Collaboration In The Field (2007-2016), Kim M. Thompson, Kasey Garrison, Carolina Santelices-Werchez, Paulina Arellano-Rojas, Danilo Reyes-Lillo

Faculty Publications

Ensuring access to published research is increasingly important for demonstrating research impact, supporting wide readership, creating interest in collaboration, and making way for funding opportunities. This article provides a bibliometric analysis of publications from 2007-2016 in the Web of Science (WOS) database to update understanding of recent international library science research as a means of discussing research impact and scientific collaboration. The methodology is a descriptive analysis of publications retrieved from the WOS database using keywords “library science” and WOS-generated subject descriptor “Information Science & Library Science.” Analysis focused on descriptive data related to our research questions including representation of …

This One Fear, Gerald A. Klingbeil

Faculty Publications

No abstract provided.

Meeting Report Of The Third Annual Tri-Service Microbiome Consortium Symposium, J Philip Karl, Robyn A. Barbato, Laurel A. Doherty, Aarti Gautam, Sarah M. Glaven, Robert J. Kokoska, Dagmar Leary, Rebecca Mickol, Matthew A. Perisin, Andrew J. Hoisington, Edward J. Van Opstal, Vanessa Varaljay, Nancy Kelley-Loughnane, Camilla A. Mauzy, Michael S. Goodson, Jason W. Soares

Faculty Publications

The Tri-Service Microbiome Consortium (TSMC) was founded to enhance collaboration, coordination, and communication of microbiome research among U.S. Department of Defense (DoD) organizations and to facilitate resource, material and information sharing among consortium members. The 2019 annual symposium was held 22–24 October 2019 at Wright-Patterson Air Force Base in Dayton, OH. Presentations and discussions centered on microbiome-related topics within five broad thematic areas: 1) human microbiomes; 2) transitioning products into Warfighter solutions; 3) environmental microbiomes; 4) engineering microbiomes; and 5) microbiome simulation and characterization. Collectively, the symposium provided an update on the scope of current DoD microbiome research efforts, highlighted …

Nutrient Timing: A Garage Door Of Opportunity?, Shawn M. Arent, Harry P. Cintineo, Bridget A. Mcfadden, Alexa Jenny Chandler, Michelle Angelique Arent

Faculty Publications

Nutrient timing involves manipulation of nutrient consumption at specific times in and around exercise bouts in an effort to improve performance, recovery, and adaptation. Its historical perspective centered on ingestion during exercise and grew to include pre- and post-training periods. As research continued, translational focus remained primarily on the impact and outcomes related to nutrient consumption during one specific time period to the exclusion of all others. Additionally, there seemed to be increasing emphasis on outcomes related to hypertrophy and strength at the expense of other potentially more impactful performance measures. As consumption of nutrients does not occur at only …

Combined And Independent Effects On Hypoxia And Tributylin On Mrna Expression And Physiology Of The Eastern Oyster (Crassostrea Virginica), Ann Fairly Barnett, James H. Gledhill, Robert J. Griffitt, Marc Slattery, Deborah J. Gochfeld, Kristine L. Willett

Faculty Publications

Oyster reefs are vital to estuarine health, but they experience multiple stressors and globally declining populations. This study examined effects of hypoxia and tributyltin (TBT) on adult Eastern oysters (Crassostrea virginica) exposed either in the laboratory or the field following a natural hypoxic event. In the laboratory, oysters were exposed to either hypoxia followed by a recovery period, or to hypoxia combined with TBT. mRNA expression of HIF1-α and Tβ-4 along with hemocyte counts, biomarkers of hypoxic stress and immune health, respectively, were measured. In field-deployed oysters, HIF1-α and Tβ-4 expression increased, while no effect on hemocytes was …

The Mbeya Antimicrobial Stewardship Team: Implementing Antimicrobial Stewardship At A Zonal-Level Hospital In Southern Tanzania, Jeffrey W. Hall, Jeannette Bouchard, P Brandon Bookstaver, Matthew S. Haldeman, Peter Kishimbo, Godlove Mbwanji, Issakwisa Mwakyula, Davance Mwasomola, Megan Seddon, Mark Shaffer, Stephanie C. Shealy, Anthony Nsojo

Faculty Publications

In 2017, Mbeya Zonal Referral Hospital (MZRH) and the University of South Carolina (UofSC) agreed to collaboratively strengthen antimicrobial prescribing in the southern highlands of Tanzania and train a new generation of clinicians in responsible antimicrobial use. Key stakeholders and participants were identified and the Mbeya Antimicrobial Stewardship Team (MAST) was created. The team identified assets brought by the collaborators, and four investigations of baseline needs were developed. These investigations included (a) a baseline clinician survey regarding antimicrobial resistance and stewardship, (b) a serial chart review of inpatient antimicrobial prescribing practices, (c) an investigation of antimicrobial resistance rates using existing …

Transcriptomic Analysis Of Extracellular Rna Governed By The Endocytic Adaptor Protein Cin1 Of Cryptococcus Deneoformans, Muxing Liu, Zhengguang Zhang, Chen Ding, Tuo Wang, Ben Kelly, Ping Wang

Faculty Publications

© Copyright © 2020 Liu, Zhang, Ding, Wang, Kelly and Wang. Membrane vesicles are considered virulence cargoes as they carry capsular and melanin components whose secretory transport is critical for the virulence of the human fungal pathogen Cryptococcus species. However, other components of the vesicles and their function in the growth and virulence of the fungus remain unclear. We have previously found that the cryptococcal intersectin protein Cin1 governs a unique Cin1-Wsp1-Cdc42 endocytic pathway required for intracellular transport and virulence. Using RNA sequencing, we compared the profiles of extracellular RNA (exRNA), including microRNA (miRNA), small interference RNA (siRNA), long noncoding …

Who Feels Entitled To Assert Legal Rights?, Elizabeth S. Chambliss

Faculty Publications

No abstract provided.

Resilience Within And Resilience Without: Mindfulness And Sustainability Programming Using An Embedded Engineering Librarian Approach, Catherine Wong, Cynthia Helen Carlson

Faculty Publications

An increasing number of students are suffering from anxiety, even before the added stress of college life. Meanwhile, the media bombards students with images of impending doom about the climate crisis and environmental collapse, potentially increasing the sense of helplessness, fear, or anger. Fostering a sense of personal and environmental resilience through contemplative practices and engagement with sustainability topics in and out of the classroom was the goal of this librarian and professor collaborative team. The team created a culture of awareness for both sustainability and mindfulness via an in-class embedded librarian model, and out of class programming over a …

Nurses' Experiences Of Organisational Learning: A Qualitative Descriptive Study, Bret Lyman, Marisa E. Biddulph, V Grace Hopper, Julie L. Brogan

Faculty Publications

Aim: To explore the validity of and expand upon a model of organisational learning in hospitals.

Background: Organisational learning is a positive change in an organisation's collective knowledge, cognition and/or action, leading to improved hospital performance. A current model offers an evidence-based, theoretical representation of organisational learning in hospitals, yet the intricacies of organisational learning in clinical practice are not fully understood. Additional guidance is needed to effectively foster and study organisational learning.

Method: Semi-structured interviews were used to gather 15 first-hand experiences of organisational learning from 14 nurses. Data were analysed via deductive thematic analysis.

Results: Organisational learning was …