Digital Commons Network^™

Public Accomodations, Public Perceptions, And Workplace Law, Joseph Seiner

Faculty Publications

No abstract provided.

Task-Based Functional Connectivity And Blood-Oxygen-Level-Dependent Activation During Within-Scanner Performance Of Lumbopelvic Motor Tasks: A Functional Magnetic Resonance Imaging Study, Mark K. Jordon, Jill Campbell Stewart Pt,Phd, Sheri P. Silfies, Paul F. Beattie

Faculty Publications

There are a limited number of neuroimaging investigations into motor control of the lumbopelvic musculature. Most investigation examining motor control of the lumbopelvic musculature utilize transcranial magnetic stimulation (TMS) and focus primarily on the motor cortex. This has resulted in a dearth of knowledge as it relates to how other regions of the brain activate during lumbopelvic movement. Additionally, task-based functional connectivity during lumbopelvic movements has not been well elucidated. Therefore, we used functional magnetic resonance imaging (fMRI) to examine brain activation and ROI-to-ROI task-based functional connectivity in 19 healthy individuals (12 female, age 29.8 ± 4.5 years) during the …

Refugee Food Insecurity & Technology: Surfacing Experiences Of Adaptation, Navigation, Negotiation And Sharing, Reem Talhouk, Kyle Montague, Hala Ghattas, Vera Araujo-Soares, Balsam Ahmad, Madeline Balaam

Faculty Publications

With the Syrian crisis still ongoing, 91% of Syrian refugee families in Lebanon do not have adequate access to safe and sufficient food. There has been a drive for technological innovation in humanitarian food assistance. To further inform such innovation, we used an Experience-Centred Design approach to gain a holistic understanding of the experiences of refugee food insecurity and how refugees envision technologies can support them. Design engagements with 13 women in an informal refugee settlement in Lebanon were conducted. The findings presented in this paper highlight that coping with food insecurity consists of experiences of adaptation, navigation, negotiation and …

The Faith, Activity, And Nutrition (Fan) Dissemination And Implementation Study: Changes In And Maintenance Of Organizational Practices Over 24 Months In A Statewide Initiative, Sarah Wilcox Phd, Kelsey R. Day, Ruth P. Saunders, Danielle E. Jake-Schoffman, Andrew T. Kaczynski, Jessica Stucker, Caroline G. Dunn, John Bernhart Ph.D.

Faculty Publications

Background

Few studies have examined the impact of ecological health promotion interventions on organizational practices over time, especially in faith-based settings. This statewide dissemination and implementation study examined change in organizational practices and their predictors across a 24-month period, as well as maintenance of change.

Methods

Using a pre-post quasi-experimental design, church coordinators from 92 United Methodist Churches in South Carolina (42% predominantly African American congregations) completed surveys at baseline, and immediate, 12-, and 24-months post-training regarding physical activity (PA) and healthy eating (HE) organizational practices consistent with the Faith, Activity, and Nutrition (FAN) program (opportunities, policies, pastor support, messages) …

Impacts Of Climate Change And Heat Stress On Farmworkers' Health: A Scoping Review, Moussa El Khayat, Dana A. Halwani, Layal Hneiny, Ibrahim Alameddine, Mustapha A. Haidar, Rima R. Habib

Faculty Publications

Due to the continuous rise of global temperatures and heatwaves worldwide as a result of climate change, concerns for the health and safety of working populations have increased. Workers in the food production chain, particularly farmworkers, are especially vulnerable to heat stress due to the strenuous nature of their work, which is performed primarily outdoors under poor working conditions. At the cross-section of climate change and farmworkers' health, a scoping review was undertaken to summarize the existing knowledge regarding the health impacts associated with climate change and heat stress, guide future research toward better understanding current and future climate change …

Fatal Neurodissemination And Sars-Cov-2 Tropism In K18-Hace2 Mice Is Only Partially Dependent On Hace2 Expression, Mariano Carossino, Devin Kenney, Aoife K. O’Connell, Paige Montanaro, Anna E. Tseng, Hans P. Gertje, Kyle A. Grosz, Maria Ericsson, Bertrand R. Huber, Susanna A. Kurnick, Saravanan Subramaniam, Thomas Kirkland, Joel R. Walker, Kevin P. Francis, Alexander D. Klose, Neal Paragas, Markus Bosmann, Mohsan Saeed, Udeni Balasuriya, Florian Douam, Nicholas Crossland

Faculty Publications

No abstract provided.

Extreme Events, Energy Security And Equality Through Micro- And Macro-Levels: Concepts, Challenges And Methods, Chien Fei Chen, Thomas Dietz, Nina H. Fefferman, Jamie Greig, Kristen Cetin, Caitlin Robinson, Laura Arpan, Marcel Schweiker, Bing Dong, Wenbo Wu, Yue Li, Hongyu Zhou, Jianzhong Wu, Jin Wen, Joshua S. Fu, Tianzhen Hong, Da Yan, Hannah Nelson, Yimin Zhu, Xueping Li, Le Xie, Rachel Fu

Faculty Publications

Low-income households face long-standing challenges of energy insecurity and inequality (EII). During extreme events (e.g., disasters and pandemics) these challenges are especially severe for vulnerable populations reliant on energy for health, education, and well-being. However, many EII studies rarely incorporate the micro- and macro-perspectives of resilience and reliability of energy and internet infrastructure and social-psychological factors. To remedy this gap, we first address the impacts of extreme events on EII among vulnerable populations. Second, we evaluate the driving factors of EII and how they change during disasters. Third, we situate these inequalities within broader energy systems and pinpoint the importance …

Writing By Presidential Example: The First Inaugural Addresses Of Reagan And Obama, Douglas E. Abrams

Faculty Publications

This article is about two recent U.S. presidents who differed from one another in prominent respects. One entered the Oval Office as a staunch Republican; the other entered as a staunch Democrat. One was one of the oldest men ever to serve in the Oval Office; the other was one of the youngest. The pair assumed contrasting positions on the political spectrum.

Despite these differences, however, the pair – Ronald Reagan and Barack Obama – shared an important common denominator. As president, both achieved recognition as “great communicators,” thanks in large part to their speeches marked by dexterity with the …

Cancer Incidence, Mortality, Years Of Life Lost, Years Lived With Disability, And Disability-Adjusted Life Years For 29 Cancer Groups From 2010 To 2019 A Systematic Analysis For The Global Burden Of Disease Study 2019, Ismaeel Yunusa Ph.D., Jonathan M. Kocarnik, Kelly Compton, Frances E. Dean, Weijia Fu, Brian L. Gaw, Et. Al.

Faculty Publications

Importance The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden.

Objective To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019.

Evidence Review The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite …

Us Agricultural University Students' Mental Well-Being And Resilience During The First Wave Of Covid-19: Discordant Expectations And Experiences Across Genders, Mariah D. Ehmke, Bhagyashree Katare, Kristin Kiesel, Jason S. Bergtold, Jerrod M. Penn, Kathryn A. Boys

Faculty Publications

The coronavirus disease 2019 (COVID-19) pandemic's first wave led to declining mental health and life satisfaction outcomes for college students, especially women. While women in undergraduate agricultural programs outperformed men academically prior to and during the pandemic, the achievement may have come at personal cost, especially for those women with fewer personal and environmental resiliency resources. Our research objective was to expand on personal, social, and environmental factors linked with lower mental health and life satisfaction scores for students in agriculture during the pandemic. We measured the influence of such factors across gender-based mental health and life satisfaction outcomes. Our …

A Comparison Of Hay And Fish Emulsion-Infused Water As Oviposition Attractants For The Cdc Gravid Trap, Timothy D. Mcnamara, Kristen Healy

Faculty Publications

Multiple oviposition attractants are used for Culex (Diptera: Culicidae) mosquito surveillance in the CDC Gravid Trap, including hay and fish emulsion-infused water. Despite the use of both in the United States, no research has compared their attractiveness. We conducted trapping throughout Louisiana to assess the attractiveness of hay and fish emulsion-infused water in various habitat types and climates. Our results indicate that fish emulsion-infused water attracts more mosquitoes overall, more Culex quinquefasciatus (Say, 1823), and a wider diversity of mosquitoes than hay-infused water. This trend was maintained, regardless of habitat type or climate.

Resistant Starch Type 2 And Whole Grain Maize Flours Enrich Different Intestinal Bacteria And Metatranscriptomes, Zachary A. Bendiks, Justin Guice, Diana Coulon, Anne M. Raggio, Ryan C. Page, Diana G. Carvajal-Aldaz, Meng Luo, David A. Welsh, Brian D. Marx, Christopher M. Taylor, Claudia Husseneder, Michael J. Keenan, Maria L. Marco

Faculty Publications

The intestinal microbiota of Sprague-Dawley (SD) rats were investigated following consumption of diets containing refined high-amylose cornstarch (RS), waxy whole-grain flour from maize (WG), or high-amylose whole-grain flour (WG + RS) together with moderate (MF, 30% of energy) or high (HF, 42% of energy) levels of fat. Compared with control (CON) diets, RS reduced bacterial alpha-diversity and enriched Bacteroidetes and WG increased Lactobacillus proportions by three-fold. WG + RS conferred a combined effect, but the changes were attenuated and greater inter-individual variation was observed. Proportions of fiber-degrading bacterial taxa were inversely correlated with cecal pH. Notably, there was little influence …

Genome-Wide Pleiotropy Analysis Identifies Novel Blood Pressure Variants And Improves Its Polygenic Risk Scores, Xiaofeng Zhu, Luke Zhu, Heming Wang, Richard S. Cooper, Aravinda Chakravarti

Faculty Publications

Systolic and diastolic blood pressure (S/DBP) are highly correlated modifiable risk factors for cardiovascular disease (CVD). We report here a bidirectional Mendelian Randomization (MR) and horizontal pleiotropy analysis of S/DBP summary statistics from the UK Biobank (UKB)-International Consortium for Blood Pressure (ICBP) (UKB-ICBP) BP genome-wide association study and construct a composite genetic risk score (GRS) by including pleiotropic variants. The composite GRS captures greater (1.11–3.26 fold) heritability for BP traits and increases (1.09- and 2.01-fold) Nagelkerke's R2 for hypertension and CVD. We replicated 118 novel BP horizontal pleiotropic variants including 18 novel BP loci using summary statistics from the Million …

Implementation Of A Longitudinal Critical Care Fellowship Ultrasound Curriculum, Allison C. Young, Christine Butts, Bennett P. Deboisblanc, Richard S. Tejedor, Stephen P. Kantrow, Matthew R. Lammi

Faculty Publications

Background: The use of point-of-care ultrasound as a diagnostic and interventional tool is rapidly becoming standard of care in critical care medicine; a standardized training curriculum is needed to ensure provider proficiency. Objective: This study aimed to describe a longitudinal critical care ultrasound (CCUS) curriculum in a pulmonary critical care medicine (PCCM) fellowship training program. It evaluated the curriculum’s impact on fellows’ knowledge, skills, and self-reported confidence and retention of these attributes. Methods: We conducted a prospective observational study of a longitudinal CCUS training program within a single PCCM fellowship training program. Knowledge, skills, and confidence of 22 fellows were …

Decreasing Phosphorus Fertility To Reduce Sweet Potato Root Growth During Container-Grown Transplant Production, L. Rouse, J. Beasley, D. Labonte, J. Kuehny

Faculty Publications

Sweetpotato [Ipomoea batatas (L.) Lam.], grown as an edible ornamental, is propagated in home gardens using locally purchased transplants. However, vigorous growth of sweetpotato limits the period of transplant salability due to root confinement. The objective of the experiment was to evaluate reductions in phosphorus (P) fertility to slow transplant root growth and extend the period of salability. Cuttings were planted into containers and fertilized at 0, 5 (0.0007), 10 (0.0012), 15 (0.0020), 20 (0.0024), and 31 mg P.L-1 (0.0040 oz P.gal-1) using a modified Hoagland solution. All transplants fertilized at 5 mg P.L-1 increased in shoot length, color, and …

The Influence Of Whey Protein Heating Parameters On Their Susceptibility To Digestive Enzymes And The Antidiabetic Activity Of Hydrolysates, Kungnang Bunsroem, Witoon Prinyawiwatkul, Siwatt Thaiudom

Faculty Publications

The inhibition of dipeptidyl peptidase-IV (DPP-IV) and the release of glucagon-like peptide-1 (GLP-1) could normalize blood glucose levels in diabetic patients. This study evaluated the susceptibility of whey proteins to enzyme hydrolysis and the antidiabetic properties of protein hydrolysates from β-lactoglobulin (β-LG) and α-lactalbumin (α-LA) solutions compared with whey protein isolate (WPI) solution treated at different heating temperatures (65, 75, and 85◦ C). α-LA hydrolysate provided the lowest degree of hydrolysis (DH). Those heating temperatures did not significantly affect the DH of all protein hydrolysates. α-LA hydrolysate significantly increased GLP-1 levels and DPP-IV inhibitory activity more than β-LG hydrolysate. WPI …

Personalized 3d-Printed Anthropomorphic Whole-Body Phantom Irradiated By Protons, Photons, And Neutrons, Hunter Tillery, Meagan Moore, Kyle J. Gallagher, Phillip J. Taddei, Erick Leuro, David Argento, Gregory Moffitt, Marissa Kranz, Margaret Carey, Steven B. Heymsfield, Wayne D. Newhauser

Faculty Publications

The objective of this study was to confirm the feasibility of three-dimensionally-printed (3D-printed), personalized whole-body anthropomorphic phantoms for radiation dose measurements in a variety of charged and uncharged particle radiation fields. We 3D-printed a personalized whole-body phantom of an adult female with a height of 154.8 cm, mass of 90.7 kg, and body mass index of 37.8 kg/m2. The phantom comprised of a hollow plastic shell filled with water and included a watertight access conduit for positioning dosimeters. It is compatible with a wide variety of radiation dosimeters, including ionization chambers that are suitable for uncharged and charged particles. Its …

Evaluating Stratified Substrates Effect On Containerized Crop Growth Under Varied Irrigation Strategies, Kristopher S. Criscione, Jeb S. Fields, Jim S. Owen, Lisa Fultz, Edward Bush

Faculty Publications

Growers rely on soilless substrates to provide sufficient water and nutrients to containerized crops. Traditional bark-based substrates are engineered to have relatively low water-holding capabilities, which can lead to nonuniform rewetting patterns and inefficient usage of water resources. Engineering substrates to redistribute water dynamics and maximize aeration within the container may improve water resource efficiencies. The goal of this study was to evaluate whether more efficient irrigation schedules can be used when stratifying unique substrates within a container for added crop water and nutrient efficiency. Loropetalum chinense ‘Ruby’ liners were planted and grown in a conventional pine bark substrate or …

The Global Virome In One Network (Virion): An Atlas Of Vertebrate-Virus Associations, Colin J. Carlson, Rory J. Gibb, Gregory F. Albery, Liam Brierley, Ryan P. Connor, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Maxwell J. Farrell, Hannah K. Frank, Renata L. Muylaert, Timothée Poisot, Angela L. Rasmussen, Sadie J. Ryan, Stephanie N. Seifert

Faculty Publications

Data that catalogue viral diversity on Earth have been fragmented across sources, disciplines, formats, and various degrees of open sharing, posing challenges for research on macroecology, evolution, and public health. Here, we solve this problem by establishing a dynamically maintained database of vertebrate-virus associations, called The Global Virome in One Network (VIRION). The VIRION database has been assembled through both reconciliation of static data sets and integration of dynamically updated databases. These data sources are all harmonized against one taxonomic backbone, including metadata on host and virus taxonomic validity and higher classification; additional metadata on sampling methodology and evidence strength …

The H3.3 Chaperone Hira Complex Orchestrates Oocyte Developmental Competence, Rowena Smith, Andrej Susor, Hao Ming, Janet Tait, Marco Conti, Zongliang Jiang, Chih Jen Lin

Faculty Publications

Successful reproduction requires an oocyte competent to sustain early embryo development. By the end of oogenesis, the oocyte has entered a transcriptionally silenced state, the mechanisms and significance of which remain poorly understood. Histone H3.3, a histone H3 variant, has unique cell cycle-independent functions in chromatin structure and gene expression. Here, we have characterised the H3.3 chaperone Hira/Cabin1/Ubn1 complex, showing that loss of function of any of these subunits causes early embryogenesis failure in mouse. Transcriptome and nascent RNA analyses revealed that transcription is aberrantly silenced in mutant oocytes. Histone marks, including H3K4me3 and H3K9me3, are reduced and chromatin accessibility …

The Potential Of Dietary Bioactive Compounds Against Sars-Cov-2 And Covid-19-Induced Endothelial Dysfunction, Jack N. Losso

Faculty Publications

COVID-19 is an endothelial disease. All the major comorbidities that increase the risk for severe SARS-CoV-2 infection and severe COVID-19 including old age, obesity, diabetes, hypertension, respiratory disease, compromised immune system, coronary artery disease or heart failure are associated with dysfunctional endothelium. Genetics and environmental factors (epigenetics) are major risk factors for endothelial dysfunction. Individuals with metabolic syndrome are at increased risk for severe SARS-CoV-2 infection and poor COVID-19 outcomes and higher risk of mortality. Old age is a non-modifiable risk factor. All other risk factors are modifiable. This review also identifies dietary risk factors for endothelial dysfunction. Potential dietary …

Diabetes Mortality And Trends Before 25 Years Of Age: An Analysis Of The Global Burden Of Disease Study 2019, Ewerton Cousin, Bruce B. Duncan, Carolina Stein, Kanyin Liane Ong, Theo Vos, Ismaeel Yunusa Ph. D., Et Al.

Faculty Publications

Background

Methods

Real-World, Multicentre Evaluation Of The Incidence And Risk Factors For Non-Susceptible Stenotrophomonas Maltophilia Isolates, Bruce M. Jones, Jamie L. Wagner, Daniel B. Chastain, P. Brandon Bookstaver, Kayla Stover, Jason Lin, Hannah Matson, Noah White, Madalyn Motesh, Christopher M. Bland

Faculty Publications

Background

Stenotrophomonas maltophilia is a cause of infection most commonly in the opportunistic host. Trimethoprim-sulfamethoxazole and levofloxacin are considered first-line treatment agents. With reports of increasing resistance to these first-line agents, it is important to determine risk factors associated with a non-susceptible isolate.

Methods

This was a real-world, multicentre, retrospective case-control study from five centres in the southeast United States evaluating S. maltophilia. The primary outcome was risk factors associated with non-susceptibility of S. maltophilia isolates to ≥1 antimicrobial agents. Secondary outcomes include incidence of S. maltophilia non-susceptibility, all-cause mortality, and 30-day readmission rates.

Results

There were 325 patients …

An Insight Into The Microrna Profile Of The Ectoparasitic Mite Varroa Destructor (Acari: Varroidae), The Primary Vector Of Honey Bee Deformed Wing Virus, Deepak Kumar, Mohamed Alburaki, Faizan Tahir, Michael Goblirsch, John Adamczyk, Shahid Karim

Faculty Publications

The remarkably adaptive mite Varroa destructor is the most important honey bee ectoparasite. Varroa mites are competent vectors of deformed wing virus (DWV), and the Varroa-virus complex is a major determinant of annual honey bee colony mortality and collapse. MicroRNAs (miRNAs) are 22-24 nucleotide non-coding RNAs produced by all plants and animals and some viruses that influence biological processes through post-transcriptional regulation of gene expression. Knowledge of miRNAs and their function in mite biology remains limited. Here we constructed small RNA libraries from male and female V. destructor using Illumina’s small RNA-Seq platform. A total of 101,913,208 and 91,904,732 …

Athlete Identity And Mental Health Among Ncaa Division Iii Student-Athletes, Sarah Stokowski, Alison Fridley, Chris Croft, Peyton Stensland, Skye Arthur-Banning

Faculty Publications

Student-athletes oten identify with the athlete role and demonstrate high levels of athlete identity. High athlete identity leads to many unintended consequences such as low career maturity and difficulty adapting to a life beyond sport. Additionally, high athlete identity often leads to mental health concerns among the student-athlete population. Informed by self-categorization theory (Turner, 1982), the purpose of this study was to explore athlete identity and mental health among NCAA Division III student-athletes. The Athlete Identity Measurement Scale (AIMS) and The Depression Anxiety Stress Scales-21 were completed by 33 NCAA Division III student-athletes. The results demonstarted that Division III student-athletes …

The Relationship Between Dietary Intake And Sleep Quality In Endurance Athletes, Kamiah Moss, Yan Zhang, Andreas Kreutzer, Austin J. Graybeal, Ryan R. Porter, Robyn Braun-Trocchio, Meena Shah

Faculty Publications

Many endurance athletes have poor sleep quality which may affect performance and health. It is unclear how dietary intake affects sleep quality among athletes. We examined if sleep quality in endurance athletes is associated with consumption of fruit, vegetables, whole grains, dairy milk, and caffeinated beverages. Two hundred thirty-four endurance athletes (39.5 ± 14.1 year) participated in a survey. Participants provided information on demographics, anthropometry, sleep behavior and quality, and dietary intake via questionnaires. Sleep quality was assessed using the Athlete Sleep Screening Questionnaire (ASSQ) with a global score (ASSQ-global) and subscales including sleep difficulty (ASSQ-SD), chronotype (ASSQ-C), and disordered …

Introspective Meditation Before Seeking Pleasurable Activities As A Stress Reduction Tool Among College Students: A Multi-Theory Model-Based Pilot Study, Manoj Sharma, Amar Kanekar, Kavita Batra, Traci Hayes, Ram Lakhan

Faculty Publications

No abstract provided.

Delirium Associations With Antibiotics: A Pharmacovigilance Study Of The Fda Adverse Event Reporting System (Faers), Chengwen Teng, Christopher R. Frei

Faculty Publications

Background Ertapenem, cefepime, imipenem, ofloxacin, ceftazidime, clarithromycin, cefaclor, levofloxacin, linezolid, moxifloxacin, azithromycin, piperacillin-tazobactam, trimethoprim-sulfamethoxazole, metronidazole, ciprofloxacin, and cefuroxime are known to be associated with delirium. Other antibiotics may also lead to delirium, but no study has systemically compared delirium associations for many available antibiotics.

Objective The objective of this study was to evaluate the association between delirium and antibiotics using the FDA Adverse Event Reporting System (FAERS).

Methods FAERS reports from January 1, 2004 to December 31, 2018 were included in the study. Reporting odds ratios (RORs) and corresponding 95% confidence intervals (95% CI) for the association between antibiotics and …

American Heart Association Epi|Lifestyle Scientific Sessions: 2021 Meeting Highlights, Ruth Alma Turkson-Ocran, Kathryn Foti, Anika L. Hines, Debora Kamin Mukaz, Hyunju Kim, Samantha Martin, Anum Minhas, Faye L. Norby, Oluwabunmi Ogungbe, Alexander C. Razavi, Mary R. Rooney, Elisabeth L.P. Sattler, Jewel Scott Phd, Rn, Fnp-C, Alvin G. Thomas, Curtis Tilves, Amelia S. Wallace, Frances M. Wang, Mingyu Zhang, Pamela L. Lutsey, Kristie J. Lancaster

Faculty Publications

No abstract provided.

Riding The Wave: Reactive Vector-Borne Disease Policy Renders The United States Vulnerable To Outbreaks And Insecticide Resistance, Kyndall C. Dye-Braumuller, Jennifer R. Gordon, Kaci Mccoy, Danielle Johnson, Rhoel Dinglasan, Melissa Nolan Ph.D., Mph

Faculty Publications

Funding for vector-borne disease surveillance, management, and research is cyclical and reactive in the United States. The subsequent effects have yielded gross inequities nationally that unintentionally support recurrent outbreaks. This policy forum is comprised of four primary subsections that collectively identify specific areas for improvement and offer innovative solutions to address national inadequacies in vector borne disease policy and infrastructure.