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Ethnic/Racial Differences In Alcohol Use: Does Drinking Refusal Self-Efficacy Matter?, P. Priscilla Lui, Savannah M. Krantz, Michael B. Madson Aug 2022

Ethnic/Racial Differences In Alcohol Use: Does Drinking Refusal Self-Efficacy Matter?, P. Priscilla Lui, Savannah M. Krantz, Michael B. Madson

Faculty Publications

Introduction: College students—including those of Hispanic backgrounds—are at risk for hazardous drinking. Research has shown robust group differences between Hispanic and White individuals in alcohol use outcomes. The ability to resist alcohol consumption can be leveraged to reduce hazardous drinking; however, little research has examined Hispanic-White differences and whether drinking refusal self-efficacy accounts for group differences in hazardous drinking. Considering Hispanic individuals make up the largest ethnic/racial minority group in the United States, it is important to identify malleable psychological factors that prevent and reduce drinking problems. Method: Hispanic and White college students at two predominantly White institutions …


Andrews University 2022-2025 Strategic Plan - Storyline One: Access, Andrea Luxton Aug 2022

Andrews University 2022-2025 Strategic Plan - Storyline One: Access, Andrea Luxton

Faculty Publications

No abstract provided.


Improved Building-Specific Flood Risk Assessment And Implications Of Depth-Damage Function Selection, Ehab Gnan, Carol J. Friedland, Md Adilur Rahim, Rubayet Bin Mostafiz, Robert V. Rohli, Fatemeh Orooji, Arash Taghinezhad, Jasmin Mcelwee Aug 2022

Improved Building-Specific Flood Risk Assessment And Implications Of Depth-Damage Function Selection, Ehab Gnan, Carol J. Friedland, Md Adilur Rahim, Rubayet Bin Mostafiz, Robert V. Rohli, Fatemeh Orooji, Arash Taghinezhad, Jasmin Mcelwee

Faculty Publications

Average annual loss (AAL) is traditionally used as the basis of assessing flood risk and evaluating risk mitigation measures. This research presents an improved implementation to estimate building-specific AAL, with the flood hazard of a building represented by the Gumbel extreme value distribution. AAL is then calculated by integrating the area under the overall loss-exceedance probability curve using trapezoidal Riemann sums. This implementation is compared with existing AAL estimations from flood risk assessment. A sensitivity analysis is conducted to examine the variability in AAL results based on depth-damage function (DDF) choice. To demonstrate the methodology, a one-story single-family residence is …


Covid-19 In The United States As Affective Frame, John Protevi Aug 2022

Covid-19 In The United States As Affective Frame, John Protevi

Faculty Publications

In this paper I attempt to contribute to the developing field of “political philosophy of mind.” To render concrete the notion of “affective frame,” a social situation which pre-selects for salience and valence of environmental factors relative to a subject’s life, I conduct a case study of a deleterious socially instituted affective frame, which, during the early days of the COVID19 pandemic in the United States, produced individuated circumstances that came crashing down on “essential workers” who were forced into a double bind. We saw here an untenable and ultimately fatal situation that forced a choice between, on the one …


Adolescent-Reported Household Food Insecurity And Adolescents' Poor Mental And Physical Health And Food Insufficiency In Kenya, Amanda S. Mcrell, Maryah S. Fram, Edward A. Frongillo Jr. Aug 2022

Adolescent-Reported Household Food Insecurity And Adolescents' Poor Mental And Physical Health And Food Insufficiency In Kenya, Amanda S. Mcrell, Maryah S. Fram, Edward A. Frongillo Jr.

Faculty Publications

Background

Assessing adolescents’ experiences of food insecurity in households is important for promoting healthy development. Although parental reports have been traditionally used, emerging research highlights the importance of child and adolescent reports of the household food environment.

Objectives

Extending research from high- and upper-middle-income countries, this study of adolescent compared with adult reports of household food insecurity in Kenya, a lower-middle-income country, examined 1) prevalence of and correspondence between adolescent and adult reports of household food insecurity, and 2) associations of adolescent and adult reports of household food insecurity with adolescent nonnutritional and nutritional outcomes.

Methods

Using data …


Inhibition Of Cdk8/19 Mediator Kinase Potentiates Her2-Targeting Drugs And Bypasses Resistance To These Agents In Vitro And In Vivo, Xiaokai Ding, Amanda C. Sharko, Martina S.J. Mcdermott, Gary P. Schools, Alexander Chumanevich, Hao Ji, Jing Li, Li Zhang, Zachary T. Mack, Vitali Sikirzhytski, Michael Shtutman, Laura Ivers, Norma O'Donovan, John Crown, Balazs Gyorffy, Mengqian Chen, Igor Roninson, Eugenia Broude Aug 2022

Inhibition Of Cdk8/19 Mediator Kinase Potentiates Her2-Targeting Drugs And Bypasses Resistance To These Agents In Vitro And In Vivo, Xiaokai Ding, Amanda C. Sharko, Martina S.J. Mcdermott, Gary P. Schools, Alexander Chumanevich, Hao Ji, Jing Li, Li Zhang, Zachary T. Mack, Vitali Sikirzhytski, Michael Shtutman, Laura Ivers, Norma O'Donovan, John Crown, Balazs Gyorffy, Mengqian Chen, Igor Roninson, Eugenia Broude

Faculty Publications

Breast cancers (BrCas) that overexpress oncogenic tyrosine kinase receptor HER2 are treated with HER2-targeting antibodies (such as trastuzumab) or small-molecule kinase inhibitors (such as lapatinib). However, most patients with metastatic HER2+BrCa have intrinsic resistance and nearly all eventually become resistant to HER2-targeting therapy. Resistance to HER2-targeting drugs frequently involves transcriptional reprogramming associated with constitutive activation of different signaling pathways. We have investigated the role of CDK8/19 Mediator kinase, a regulator of transcriptional reprogramming, in the response of HER2+BrCa to HER2-targeting drugs. CDK8 was in the top 1% of all genes ranked by correlation with shorter relapse-free …


The Association Between Dietary Inflammatory Index, Dietary Antioxidant Index, And Mental Health In Adolescent Girls: An Analytical Study, Parvin Dehghan, Marzieh Nejati, Amir Almasi-Hashiani, Sevda Saleh-Ghadimi, Rezza Parsi, Hamed Jafari-Vayghan, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd Aug 2022

The Association Between Dietary Inflammatory Index, Dietary Antioxidant Index, And Mental Health In Adolescent Girls: An Analytical Study, Parvin Dehghan, Marzieh Nejati, Amir Almasi-Hashiani, Sevda Saleh-Ghadimi, Rezza Parsi, Hamed Jafari-Vayghan, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd

Faculty Publications

Background Diet is considered as one of the modifiable factors that appears to exert a vital role in psychological status. In this way, we designed this study to examine the association between dietary inflammatory index (DII), dietary antioxidant index (DAI), and mental health in female adolescents. Methods This cross-sectional study included 364 female adolescents selected from high schools in the five regions of Tabriz, Iran. A 3-day food record was used to extract the dietary data and calculate DII/DAI scores. DII and DAI were estimated to assess the odds of depression, anxiety, and stress based on the Depression Anxiety Stress …


Trumpism, Climate And Covid: Social Bases Of The New Science Rejection, Lawrence C. Hamilton Aug 2022

Trumpism, Climate And Covid: Social Bases Of The New Science Rejection, Lawrence C. Hamilton

Faculty Publications

Generalized structural equation modeling (GSEM) of 2021 US survey data tests Trumpism (approval of ex-president Trump) as an emergent political-identity indicator, descendant from the classical divisions by party and ideology but exerting its own distinct influence on two existentially important cases of science rejection: the reality of anthropogenic climate change (ACC), and vaccination against COVID-19.


Supplemental Nutrition Assistance Program (Snap)-Authorised Store Marketing Environments In Louisiana Encourage The Selection Of Less Nutritious Foods And Beverages, Bailey Houghtaling, Melissa Cater, Nila Pradhananga, Denise Holston Aug 2022

Supplemental Nutrition Assistance Program (Snap)-Authorised Store Marketing Environments In Louisiana Encourage The Selection Of Less Nutritious Foods And Beverages, Bailey Houghtaling, Melissa Cater, Nila Pradhananga, Denise Holston

Faculty Publications

Marketing influences consumers’ dietary purchases. However, little is known about marketing environments in Supplemental Nutrition Assistance Program (SNAP)-authorised stores. The present study explored SNAP-authorised store marketing environments in Louisiana by rurality, store ownership and store type (n 42). Sampling methods were designed to include randomly selected stores in each geographic area of the state. The GroPromo was used to measure placement, promotion, and child-focused aspects of marketing strategies used for healthier (fruits and vegetables) and less healthy products (chips, candy, sugar-sweetened beverages, child-focused cereal) in medium- and high-prominence marketing areas. In using multivariate analysis of variance (MANOVA) (P < 0⋅05) for data analysis, variations in GroPromo scores were found among SNAP-authorised stores by rurality (P < 0⋅05) and store ownership (P < 0⋅001); no differences were found by store type (P > 0⋅05). Future …


A Primer On The Factories Of The Future, Noble Anumbe, Clint Saidy, Ramy Harik Aug 2022

A Primer On The Factories Of The Future, Noble Anumbe, Clint Saidy, Ramy Harik

Faculty Publications

In a dynamic and rapidly changing world, customers’ often conflicting demands have continued to evolve, outstripping the ability of the traditional factory to address modern-day production challenges. To fix these challenges, several manufacturing paradigms have been proposed. Some of these have monikers such as the smart factory, intelligent factory, digital factory, and cloud-based factory. Due to a lack of consensus on general nomenclature, the term Factory of the Future (or Future Factory) has been used in this paper as a collective euphemism for these paradigms. The Factory of the Future constitutes a creative convergence of multiple technologies, techniques, and capabilities …


Association Of Caregiver Attitudes With Adolescent Hpv Vaccination In 13 Southern Us States, Lavanya Vasudevan, Jan Ostermann Ph.D., Yunfei Wang, Sayward Harrison, Valerie Yelverton, Laura J. Fish, Charnetta Williams, Emmanuel B. Walter Aug 2022

Association Of Caregiver Attitudes With Adolescent Hpv Vaccination In 13 Southern Us States, Lavanya Vasudevan, Jan Ostermann Ph.D., Yunfei Wang, Sayward Harrison, Valerie Yelverton, Laura J. Fish, Charnetta Williams, Emmanuel B. Walter

Faculty Publications

Background and objectives: HPV vaccination coverage is lower than that of other adolescent vaccines in the southern US. This study sought to characterize caregiver attitudes associated with adolescent HPV vaccination in the southern US and to inform interventions to promote HPV vaccination. Methods: From December 2019 – January 2020, caregivers of adolescents (ages 9–17 years) living in thir- teen southern US states were recruited from a nationally-representative online survey panel. Caregivers (N = 1,105) completed a cross-sectional survey that assessed general adolescent vaccine attitudes as well as those associated with the HPV vaccine and HPV vaccination decision-making. The primary study …


Gender Disparities In Increased Parenting Time During The Covid-19 Pandemic: A Research Note, Jennifer Augustine, Kate Prickett Aug 2022

Gender Disparities In Increased Parenting Time During The Covid-19 Pandemic: A Research Note, Jennifer Augustine, Kate Prickett

Faculty Publications

Public health measures aimed at curbing the transmission of COVID-19 increased parenting responsibilities during the early stages of the pandemic. This research note examines time-use data from the American Time Use Surveys to provide several fresh insights as to how mothers took on a disproportionate share of this responsibility compared to fathers during this period. First, the gender gap in total parenting time narrowed by 18%. Meanwhile, the gender disparity in time in educational activities increased by 113% and was not explained by changes in mothers’ labor force participation. Mothers also took on 20% more time in secondary caregiving compared …


Profile Of Commercialized Aphicides On The Survivorship And Feeding Behavior Of The Cotton Aphid, Aphis Gossypii, Flinn M. O'Hara, Jeffrey A. Davis, Daniel R. Swale Aug 2022

Profile Of Commercialized Aphicides On The Survivorship And Feeding Behavior Of The Cotton Aphid, Aphis Gossypii, Flinn M. O'Hara, Jeffrey A. Davis, Daniel R. Swale

Faculty Publications

The cotton aphid, Aphis gossypii Glover (Hemiptera: Aphididae), is one of the most destructive agricultural pests due to photosynthate removal and horizontal transmission of plant viruses. Horizontal transmission of plant viruses by aphids occurs during distinct feeding behavioral events, such as probing for non-persistent viruses or phloem feeding for persistent viruses. We employed toxicity bioassays and electrical penetration graph (EPG) methodology to compare toxicity and quantify changes to feeding behavior and toxicity of A. gossypii after exposure to commercialized aphicides. Commercialized aphicides containing flupyradifurone, sulfoxaflor, thiamethoxam, thiamethoxam + lambda cyhalothrin, and bifenthrin induced >90% aphid mortality within 4 h of …


Relational Turbulence And Social Network Engagement During The Summer Of Covid-19: A Repeated Measures, Dyadic Analysis, Kellie S. Brisini, Denise H. Solomon Aug 2022

Relational Turbulence And Social Network Engagement During The Summer Of Covid-19: A Repeated Measures, Dyadic Analysis, Kellie S. Brisini, Denise H. Solomon

Faculty Publications

Background/Purpose: Relational turbulence theory suggests that changes in and around relationships create the potential for relational turbulence when everyday routines and scripts are upended and communication becomes polarized. In turn, perceptions of a romantic relationship as chaotic or tumultuous can influence a person’s engagement with their social network. Alternately, previous research also suggests that engagement with friends and family has the potential to influence married partner’s relationship quality. Research Design: This study examined these propositions among a sample of married couples (N = 64, 128 individuals) whose daily experiences and relationship dynamics changed during the COVID-19 lockdown period. Results/Conclusions: Based …


Developing A Conceptual Passive Contact Tracing System For Commercial Buildings Using Wifi Indoor Positioning, Sorena Vosoughkhosravi, Amirhosein Jafari Aug 2022

Developing A Conceptual Passive Contact Tracing System For Commercial Buildings Using Wifi Indoor Positioning, Sorena Vosoughkhosravi, Amirhosein Jafari

Faculty Publications

Contact tracing is one of the critical tools for fighting against pandemic disease outbreaks, such as the fast-growing SARS-CoV-2 virus and its different variants. At present, automated contact tracing systems face two main challenges: (1) requiring application installation on smart devices and (2) protecting the users’ privacy. This study introduces a conceptual passive contact tracing system using indoor WiFi positioning to address these challenges and investigate the role of such a system in commercial buildings. In this regard, this study uses a simulated small-office layout in a case study to demonstrate the applicability of the proposed system. The special use …


The Need For A Framework Addressing The Temporal Aspects Of Fish Sperm Motility Leading To Community-Level Standardization, Harvey Blackburn, Leticia Torres, Yue Liu, Terrence R. Tiersch Aug 2022

The Need For A Framework Addressing The Temporal Aspects Of Fish Sperm Motility Leading To Community-Level Standardization, Harvey Blackburn, Leticia Torres, Yue Liu, Terrence R. Tiersch

Faculty Publications

Motility is a widely available parameter that can be used to assess sperm quality of aquatic species. Sperm from fishes with external fertilization usually undergo a dynamic and short-lived period of motility after activation. The common practice of assigning a single value at an arbitrary peak of motility presents challenges for reproducibility, community-level standardization, and comparisons across studies. This study aimed to explore statistical approaches to standardize motility reporting, and to develop an initial framework for community-level standards. Sperm samples from 14 zebrafish (Danio rerio) with a total of 21,705 cells were analyzed by use of computer-assisted sperm analysis with …


Interviewing For Residency Positions While Completing A Graduate Degree: Considerations For Graduate Students, Mentors, And Program Directors, Wayne Newhauser, Garrett Pitcher, Christine Swanson, Samuel G. Armato, Hania Al-Hallaq Aug 2022

Interviewing For Residency Positions While Completing A Graduate Degree: Considerations For Graduate Students, Mentors, And Program Directors, Wayne Newhauser, Garrett Pitcher, Christine Swanson, Samuel G. Armato, Hania Al-Hallaq

Faculty Publications

No abstract provided.


Pyrolysis Temperature Affects Dissolved Phosphorus And Carbon Levels In Alkali-Enhanced Biochar And Its Soil Applications, Meng Wang, Jim J. Wang, Jong Hwan Park, Jian Wang, Xudong Wang, Zuoping Zhao, Fengmin Song, Bo Tang Aug 2022

Pyrolysis Temperature Affects Dissolved Phosphorus And Carbon Levels In Alkali-Enhanced Biochar And Its Soil Applications, Meng Wang, Jim J. Wang, Jong Hwan Park, Jian Wang, Xudong Wang, Zuoping Zhao, Fengmin Song, Bo Tang

Faculty Publications

Alkali-enhanced biochars, as an environment-friendly material, combine the advantages of biomass nutrients and carbon fixation. In this study, rice-residue-derived biochars were evaluated for P and C solubility and their amendment upon plant P uptake. Biochars from rice straw (RS) and husk (RH), including raw biochar without alkaline pretreatment (0B), alkali-enhanced biochars with KOH (5KB, 5 g KOH per 100 g feedstock;10KB, 10 g KOH per 100 g feedstock), K2CO3 (5K2B, 5 g K2CO3 per 100 g feedstock; 10K2B, 10 g K2CO3 per 100 g feedstock), and CaO (5CB, 5 g CaO per 100 g feedstock; 10CB,10 g CaO per 100 …


Alteration Of Biomolecular Conformation By Aluminum-Implications For Protein Misfolding Disease, Yuhai Zhao, Aileen I. Pogue, Peter N. Alexandrov, Leslie G. Butler, Wenhong Li, Vivian R. Jaber, Walter J. Lukiw Aug 2022

Alteration Of Biomolecular Conformation By Aluminum-Implications For Protein Misfolding Disease, Yuhai Zhao, Aileen I. Pogue, Peter N. Alexandrov, Leslie G. Butler, Wenhong Li, Vivian R. Jaber, Walter J. Lukiw

Faculty Publications

The natural element aluminum possesses a number of unique biochemical and biophysical properties that make this highly neurotoxic species deleterious towards the structural integrity, conformation, reactivity and stability of several important biomolecules. These include aluminum’s (i) small ionic size and highly electrophilic nature, having the highest charge density of any metallic cation with a Z2/r of 18 (ionic charge +3, radius 0.5 nm); (ii) inclination to form extremely stable electrostatic bonds with a tendency towards covalency; (iii) ability to interact irreversibly and/or significantly slow down the exchange-rates of complex aluminum–biomolecular interactions; (iv) extremely dense electropositive charge with one …


Invited Perspective: Existing Rules For Disinfection By-Products Are Good, But They Are Not Enough, Susan D. Richardson Aug 2022

Invited Perspective: Existing Rules For Disinfection By-Products Are Good, But They Are Not Enough, Susan D. Richardson

Faculty Publications

No abstract provided.


Mindfulness, Psychological Distress, And Somatic Symptoms Among Women Engaged In Sex Work In China, Cheuk Chi Tam, Yuejiao Zhao, Shan Qiao, Xiaoming Li, Zhiyong Shen Aug 2022

Mindfulness, Psychological Distress, And Somatic Symptoms Among Women Engaged In Sex Work In China, Cheuk Chi Tam, Yuejiao Zhao, Shan Qiao, Xiaoming Li, Zhiyong Shen

Faculty Publications

Women engaged in sex work (WSW) in China encounter numerous disadvantages (e.g., exposure to violence) and have substantial risk for psychological distress and somatic symptoms. Intervention literature has attended to mindfulness, which is a protective factor for psychological outcomes, and its influences can further improve physical health. However, mindfulness has not been well studied in WSW. We aimed to examine the association among mindfulness, psychological distress, and somatic symptoms among Chinese WSW. Data were collected from 410 WSW in Guangxi, China, using an anonymous, self-administered survey evaluating demographics, mindfulness, psychological distress (i.e., depression, loneliness, and perceived stress), and somatic symptoms …


The Curve Not Taken: Effects Of Covid-19 International Comparison News, Seon Woo Kim, Martina Santia, Raymond J. Pingree, Ayla Oden, Kirill Bryanov, Jessica Wyers Aug 2022

The Curve Not Taken: Effects Of Covid-19 International Comparison News, Seon Woo Kim, Martina Santia, Raymond J. Pingree, Ayla Oden, Kirill Bryanov, Jessica Wyers

Faculty Publications

International news can inform people not only about what is happening in other countries, but also about how their own country could benefit from policies that have proved successful elsewhere. Specifically, international policy comparison news, or news that compares the policies of two or more countries on the same issue, is a potentially important but underutilized and understudied form of news content. We use an experiment to test effects of exposure to news comparing the COVID-19 pandemic policies of the U.S. versus South Korea, and find that this increases knowledge of policy differences between the two countries, support for adopting …


Student Retention And Persistence In University Certificate-First Programs, Troy Martin, Randall Davies Aug 2022

Student Retention And Persistence In University Certificate-First Programs, Troy Martin, Randall Davies

Faculty Publications

While access to higher education has grown over the past few years, significant barriers exist for nontraditional students attempting to prepare for and complete postsecondary education. For these students, the traditional methods for acknowledging student achievement do not always work. This research explored the impact of earning professional certificates on nontraditional students’ confidence, motivation, and persistence. Specifically, this study evaluated the matriculation rates between two cohorts of students who participated in the online PathwayConnect program. The mixed-method study found that matriculation rates for students who were encouraged to earn a certificate increased compared to those who followed a traditional path. …


Sorption Of Cellulases In Biofilm Enhances Cellulose Degradation By Bacillus Subtilis, Yijie Deng, Shiao Y. Wang Aug 2022

Sorption Of Cellulases In Biofilm Enhances Cellulose Degradation By Bacillus Subtilis, Yijie Deng, Shiao Y. Wang

Faculty Publications

Biofilm commonly forms on the surfaces of cellulosic biomass but its roles in cellulose degradation remain largely unexplored. We used Bacillus subtilis to study possible mechanisms and the contributions of two major biofilm components, extracellular polysaccharides (EPS) and TasA protein, to submerged biofilm formation on cellulose and its degradation. We found that biofilm produced by B. subtilis is able to absorb exogenous cellulase added to the culture medium and also retain self-produced cellulase within the biofilm matrix. The bacteria that produced more biofilm degraded more cellulose compared to strains that produced less biofilm. Knockout strains that lacked both EPS and …


Securing Information On A Web Application System To Facilitate Online Blood Donation Booking, Hrishitva Patel Aug 2022

Securing Information On A Web Application System To Facilitate Online Blood Donation Booking, Hrishitva Patel

Faculty Publications

Blood donation has saved many lives in the past. According to statistics presented by the American Red Cross, a patient is in need of a blood transfusion every two seconds. There are many benefits that arise from blood donation to both the donor and the blood recipients. With blood donation, cancer patients, people involved in accidents, or those battling diseases that require blood donation have access to enough blood to sustain their survival. There is a need to digitize the blood donation booking to facilitate blood donation across the United States, and ensure patients in need of blood, receive their …


A Clinical Test To Assess Isometric Cervical Strength In Chronic Whiplash Associated Disorder (Wad): A Reliability Study, Jeff Habberfield, Geoff Schneider, Kathryn Schneider, Sozina Katuli, Lee Olson Aug 2022

A Clinical Test To Assess Isometric Cervical Strength In Chronic Whiplash Associated Disorder (Wad): A Reliability Study, Jeff Habberfield, Geoff Schneider, Kathryn Schneider, Sozina Katuli, Lee Olson

Faculty Publications

Background: Cervical spine muscle weakness is well demonstrated in individuals with chronic neck pain. There is a lack of literature evaluating clinically applicable means of assessing isometric cervical strength in chronic whiplash associated disorder (WAD). This study assessed the reliability of self-resisted isometric cervical strength testing using a handheld dynamometer. The relationship between strength and neck pain-related disability and kinesiophobia was also investigated.

Methods: Twenty subjects with chronic WAD performed maximum-efort isometric cervical fexion, extension, side fexion, and rotation against a hand held dynamometer. The dynamometer was held by the subject, who provided self-resistance. Subjects completed two sessions of testing …


Mentoring: An Essential For Novice Teachers, Kathleen Forbis, Anneris Coria-Navia, Jimmy Kijai, Larry D. Burton Aug 2022

Mentoring: An Essential For Novice Teachers, Kathleen Forbis, Anneris Coria-Navia, Jimmy Kijai, Larry D. Burton

Faculty Publications

No abstract provided.


Adolescent Transport And Unintentional Injuries: A Systematic Analysis Using The Global Burden Of Disease Study 2019, Amy E. Peden, Patricia Cullen, Kate Louise Francis, Holger Moeller, Margaret M. Peden, Ismaeel Yunusa Ph. D., Et Al. Aug 2022

Adolescent Transport And Unintentional Injuries: A Systematic Analysis Using The Global Burden Of Disease Study 2019, Amy E. Peden, Patricia Cullen, Kate Louise Francis, Holger Moeller, Margaret M. Peden, Ismaeel Yunusa Ph. D., Et Al.

Faculty Publications

Background Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10–24 years during the past three decades.

Methods Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100000 population by sex, age group (10–14, 15–19, and 20–24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We …


Optimising Predictive Models To Prioritise Viral Discovery In Zoonotic Reservoirs, Daniel J. Becker, Gregory F. Albery, Anna R. Sjodin, Timothée Poisot, Laura M. Bergner, Binqi Chen, Lily E. Cohen, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Maxwell J. Farrell, Sarah Guth, Barbara A. Han, Nancy B. Simmons, Michiel Stock, Emma C. Teeling, Colin J. Carlson Aug 2022

Optimising Predictive Models To Prioritise Viral Discovery In Zoonotic Reservoirs, Daniel J. Becker, Gregory F. Albery, Anna R. Sjodin, Timothée Poisot, Laura M. Bergner, Binqi Chen, Lily E. Cohen, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Maxwell J. Farrell, Sarah Guth, Barbara A. Han, Nancy B. Simmons, Michiel Stock, Emma C. Teeling, Colin J. Carlson

Faculty Publications

Despite the global investment in One Health disease surveillance, it remains difficult and costly to identify and monitor the wildlife reservoirs of novel zoonotic viruses. Statistical models can guide sampling target prioritisation, but the predictions from any given model might be highly uncertain; moreover, systematic model validation is rare, and the drivers of model performance are consequently under-documented. Here, we use the bat hosts of betacoronaviruses as a case study for the data-driven process of comparing and validating predictive models of probable reservoir hosts. In early 2020, we generated an ensemble of eight statistical models that predicted host–virus associations and …


Quantile Differences In The Age-Related Decline In Cardiorespiratory Fitness Between Sexes In Adults Without Type 2 Diabetes Mellitus In The United States, Andrew Ortaglia, Melissa Stansbury, Michael David Wirth, Xuemei Sui, Matteo Bottai Aug 2022

Quantile Differences In The Age-Related Decline In Cardiorespiratory Fitness Between Sexes In Adults Without Type 2 Diabetes Mellitus In The United States, Andrew Ortaglia, Melissa Stansbury, Michael David Wirth, Xuemei Sui, Matteo Bottai

Faculty Publications

Objective: To comprehensively assess the extent to which the decline in cardiorespiratory fitness (CRF) with age differs between sexes. Participants and Methods: This study used data from the Aerobics Center Longitudinal Study, conducted between September 1974 and August 2006, consisting primarily of White adults from middle-to-upper socioeconomic strata restricted to adults without type 2 diabetes mellitus (33,742 men and 9,415 women). Quantile regression models were used to estimate the differences in age-associated changes in CRF between the sexes, estimated using a maximal treadmill test. Results: For adults aged up to 45 years, significant differences in slopes relating to age and …