Digital Commons Network^™

Feasibility Of An Abstract Verb Naming Treatment For Aphasia, Dallin J. Bailey, Lisa Bunker, Julie L. Wambaugh

Faculty Publications

Purpose

Verb production impairments in aphasia have important implications for sentence production and communication in general. Verbs with low concreteness may be especially important for certain functional uses, and yet limited data regarding their response to treatment are available. This study was designed to examine a novel behavioral treatment approach to improve low concreteness verb naming in persons with aphasia.

Method

Three persons with nonfluent aphasia participated in a single-subject experimental design research study examining the feasibility of the novel treatment. The treatment was based on approaches that target the verb as the central node of meaning during sentence construction. …

A Novel Application Of Spinning Disk Technology To Collect Plasma From Whole Blood Prior To Quantifying Plasma Rna, Naomi Rapier-Sharman, Mae-Lynn L. Hutchinson, Carlos M. Moreno, Abraham Quaye, Brian D. Poole, K. Scott Weber, William G. Pitt, Brett E. Pickett

Faculty Publications

The spinning disk technology has previously been utilized to isolate bacterial components from blood in hours instead of days. We hypothesized that this platform could be applied as an alternative approach to isolating plasma RNA from a whole blood sample. We consequently tested the efficacy of the spinning disk technology to extract plasma from whole blood upstream of RNA isolation and analysis. To do so, we collected plasma using either the spinning disk or the typical two-spin centrifuge method. We found that the spinning disk method results in significantly more hemolysis during collection than the conventional two-spin centrifuge method. However, …

The Future Of Cyanobacteria Toxicity In Estuaries Undergoing Pulsed Nutrient Inputs: A Case Study From Coastal Louisiana, Sibel Bargu, Matthew Hiatt, Kanchan Maiti, Paul Miller, John R. White

Faculty Publications

Harmful cyanobacteria blooms (cyanoHABs) are a global phenomenon, especially in calm, warm, and nutrient-rich freshwater and estuarine systems. These blooms can produce various potent toxins responsible for animal poisoning and human health problems. Nutrient-rich freshwater pulsed into estuaries affects turbidity, water temperature, salinity, and nutrient concentrations and ratios at irregular intervals, creating a highly dynamic habitat. However, the underlying processes that lead to the selective development of cyanoHABs for certain species and the fate of their toxins are still uncertain. This paper draws upon the rich body of research available for one such system, the Lake Pontchartrain Estuary, Louisiana, to …

Limnological Response Of Las Curias Reservoir, San Juan, Puerto Rico: Successful Management Of The Invasive Aquatic Fern, Salvinia Molesta, Xavier A. García-López, Jorge R. Ortiz-Zayas, Rodrigo Díaz, Aurelio Castro-Jiménez, Charles F. Wahl

Faculty Publications

The anthropogenic deterioration of aquatic ecosystems affects water resources due to agricultural malpractices, pollution from domestic septic tanks, recreational activities, and poor watershed management, among other factors. This study examines the management of Las Curias Reservoir, San Juan, Puerto Rico, after the 2016 arrival of the invasive aquatic fern Salvinia molesta. In September 2019, a community-led initiative introduced the Cyrtobagous salviniae weevil, an effective biological control agent for S. molesta, and commenced a mechanical removal campaign using an aquatic harvester. Limnological sampling (September 2019 to September 2022) and drone flights were employed to measure physicochemical and floating plant cover changes, …

Effects Of Ingested Essential Oils And Propolis Extracts On Honey Bee (Hymenoptera: Apidae) Health And Gut Microbiota, Allyson Martin Ewert, Michael Simone-Finstrom, Quentin Read, Claudia Husseneder, Vincent Ricigliano

Faculty Publications

Managed honey bee (Hymenoptera: Apidae: Apis mellifera Linnaeus) hives require frequent human inputs to maintain colony health and productivity. A variety of plant natural products (PNPs) are delivered via feeding to control diseases and reduce the use of synthetic chemical treatments. However, despite their prevalent use in beekeeping, there is limited information regarding the impact of ingested PNPs on bee health. Here, we tested the effects of different essential oils and propolis extracts on honey bee life span, nutrient assimilation, xenobiotic detoxification, and gut microbiota abundance. Brazilian propolis extract lengthened worker life span, while the other PNPs (Louisiana propolis extract, …

Labeling Effects Of Initial Juvenile Justice System Processing Decision On Youth Interpersonal Ties*, Zachary R. Rowan, Adam Fine, Laurence Steinberg, Paul J. Frick, Elizabeth Cauffman

Faculty Publications

The juvenile justice system can process youth in myriad ways. Youth who are formally processed, relative to being informally processed, may experience more public and harsh sanctions that label youth more negatively as “deviant.” Drawing on labeling theory, the current study evaluates the relative effect of formal justice system processing on the interpersonal dynamics of youth peer networks. Using data from the Crossroads Study, a multisite longitudinal sample of first-time adolescent offenders, the current study applies augmented inverse probability weighting and generalized mixed-effects models to estimate the effects of formal processing on friendship selection processes of homophily and withdrawal and …

An Agent-Based Model To Quantify Energetics, Movement And Habitat Selection Of Mid-Continent Mallards In The Mississippi Alluvial Valley, Florian G. Weller, Elisabeth B. Webb, Sean Fogenburg, William S. Beatty, Dylan Kesler, Robert H. Blenk, Kevin M. Ringelman, Matt L. Miller, Céline Arzel, John M. Eadie

Faculty Publications

The dynamics of wintering waterfowl populations at the landscape scale are the result of complex interactions of environmental, behavioral and energetic drivers. Agent-based models provide a method to directly link these factors in a spatially explicit framework and allow the emergence of patterns from the aggregation of individual agent actions. We adapted the Spatially-explicit Waterbird Agent-based Model Program (SWAMP), originally developed for waterfowl in central California, to simulate a basin-scale population of mallards (A. platyrhynchos) wintering in the Mississippi Alluvial Valley over a four-month period (November–February). Simulated agents move within the landscape, foraging on areas made available based on a …

Expanding Non-Invasive Approaches For Fish-Health Monitoring: A Survey Of The Epidermal Mucous Metabolomes Of Phylogenetically Diverse Freshwater Fish Species, Drew R. Ekman, Marina G. Evich, Jonathan D. Mosley, Jon A. Doering, Kellie A. Fay, Gerald T. Ankley, Timothy W. Collette

Faculty Publications

There is a pressing need for more-holistic approaches to fisheries assessments along with growing demand to reduce the health impacts of sample collections. Metabolomic tools enable the use of sample matrices that can be collected with minimal impact on the organism (e.g., blood, urine, and mucus) and provide high-throughput, untargeted biochemical information without the requirement of a sequenced genome. These qualities make metabolomics ideal for monitoring a wide range of fish species, particularly those under protected status. In the current study, we surveyed the relative abundances of 120 endogenous metabolites in epidermal mucus across eight freshwater fish species belonging to …

Influences Of Yogurt With Functional Ingredients From Various Sources That Help Treat Leaky Gut On Intestinal Barrier Dysfunction In Caco-2 Cells, Ricardo S. Aleman, Ryan Page, Roberto Cedillos, Ismael Montero-Fernández, Jhunior Abraham Marcia Fuentes, Douglas W. Olson, Kayanush Aryana

Faculty Publications

The impact of yogurts made with starter culture bacteria (L. bulgaricus and S. thermophilus) and supplemented with ingredients (maitake mushrooms, quercetin, L-glutamine, slippery elm bark, licorice root, N-acetyl-D-glucosamine, zinc orotate, and marshmallow root) that can help treat leaky gut were investigated using the Caco-2 cell monolayer as a measure of intestinal barrier dysfunction. Milk from the same source was equally dispersed into nine pails, and the eight ingredients were randomly allocated to the eight pails. The control had no ingredients. The Caco-2 cells were treated with isoflavone genistein (negative control) and growth media (positive control). Inflammation was stimulated using an …

Synergistic In Vitro Antiviral Effect Of Combinations Of Ivermectin, Essential Oils, And 18-(Phthalimid-2-Yl)Ferruginol Against Arboviruses And Herpesvirus, Liliana Betancur-Galvis, Orlando José Jimenez-Jarava, Fatima Rivas, William E. Mendoza-Hernández, Miguel A. González-Cardenete

Faculty Publications

Combining antiviral drugs with different mechanisms of action can help prevent the development of resistance by attacking the infectious agent through multiple pathways. Additionally, by using faster and more economical screening methods, effective synergistic drug candidates can be rapidly identified, facilitating faster paths to clinical testing. In this work, a rapid method was standardized to identify possible synergisms from drug combinations. We analyzed the possible reduction in the antiviral effective concentration of drugs already approved by the FDA, such as ivermectin (IVM), ribavirin (RIBA), and acyclovir (ACV) against Zika virus (ZIKV), Chikungunya virus (CHIKV), and herpes virus type 2 (HHV-2). …

Effect Of Sampling Method On Detection Of The Equine Uterine Microbiome During Estrus, B. A. Heil, M. Van Heule, S. K. Thompson, T. A. Kearns, E. L. Oberhaus, G. King, P. Daels, P. Dini, J. L. Sones

Faculty Publications

Bacterial endometritis is among the most common causes of subfertility in mares. It has a major economic impact on the equine breeding industry. The sensitivity of detecting uterine microbes using culture-based methods, irrespective of the sample collection method, double-guarded endometrial swab, endometrial biopsy, or uterine low-volume lavage (LVL), is low. Therefore, equine bacterial endometritis often goes undiagnosed. Sixteen individual mares were enrolled, and an endometrial sample was obtained using each method from all mares. After trimming, quality control and decontamination, 3824 amplicon sequence variants were detected in the dataset. We found using 16S rRNA sequencing that the equine uterus harbors …

Impact Of Silicon Ion Irradiation On Aluminum Nitride-Transduced Microelectromechanical Resonators, David D. Lynes, Joshua Young, Eric Lang, Hengky Chandrahalim

Faculty Publications

Microelectromechanical systems (MEMS) resonators use is widespread, from electronic filters and oscillators to physical sensors such as accelerometers and gyroscopes. These devices' ubiquity, small size, and low power consumption make them ideal for use in systems such as CubeSats, micro aerial vehicles, autonomous underwater vehicles, and micro-robots operating in radiation environments. Radiation's interaction with materials manifests as atomic displacement and ionization, resulting in mechanical and electronic property changes, photocurrents, and charge buildup. This study examines silicon (Si) ion irradiation's interaction with piezoelectrically transduced MEMS resonators. Furthermore, the effect of adding a dielectric silicon oxide (SiO₂) thin film is …

The Superfluous Rules Of Evidence, Jeffrey Bellin

Faculty Publications

There are few American legal codifications as successful as the Federal Rules of Evidence. But this success masks the project’s uncertain beginnings. The drafters of the Federal Rules worried that lawmakers would not adopt the new rules and that judges would not follow them. As a result, they included at least thirty rules of evidence that do not, in fact, alter the admissibility of evidence. Instead, these rules: (1) market the rules project, and (2) guide judges away from anticipated errors in applying the (other) nonsuperfluous rules.

Given the superfluous rules’ covert mission, it should not be surprising that the …

Second Amendment Exceptionalism: Public Expression And Public Carry, Timothy Zick

Faculty Publications

In New York State Rifle & Pistol Ass’n v. Bruen, the Supreme Court recognized a right to carry firearms in public places. The scope of that right will depend on where, why, and how governments regulated public carry during the eighteenth and perhaps nineteenth centuries. The Court claimed that its turn to history for determining the scope of Second Amendment rights “accords with” and “comports with” how the Court has interpreted First Amendment rights. This Article examines and rejects that claim, both in general and specifically as it applies to the public exercise of Second Amendment rights. Although Bruen …

The Independent Agency Myth, Neal Devins, David E. Lewis

Faculty Publications

Republicans and Democrats are fighting the wrong fight over independent agencies. Republicans are wrong to see independent agencies as anathema to hierarchical presidential control of the administrative state. Democrats are likewise wrong to reflexively defend independent agency expertise and influence. Supreme Court Justices also need to break free from this trap; the ongoing struggle over independent agencies should be about facts, not partisan rhetoric.

This Article seeks to reframe the fight over independent agencies. By surveying executive branch and independent agency department heads and supervisors during the Obama (2014) and Trump (2020) administrations, we have assembled unique and expansive data …

Technology Specificity And Equitable Access To Pharmaceuticals, Ana Santos Rutschman

Faculty Publications

Current models of production of pharmaceuticals, particularly those dependent on intellectual property (and adjacent) protections, often contribute to the highly asymmetrical and inequitable distribution of resulting outputs. These problems are especially acute when emerging pathogens cause transnational public health crises in which there is concurrent demand for the same medicines in both lower- and higher-income countries, with populations in the Global South getting very limited timely access, if any, to preventatives and life-saving medicines—even when an outbreak disproportionately affects populations in these very countries.

This essay examines an under-theorized and under-explored way to help correct this historical and persisting deficit …

Lessons From A Retiring Legal Writing Professor, Mary Ann Robinson

Faculty Publications

No abstract provided.

Entorhinal Cortical Delta Oscillations Drive Memory Consolidation, Juhee Haam, Suman Gunin, Leslie Wilson, Sydney Fry, Briana Bernstein, Eric Thomson, Hayden Noblet, Jesse Cushman, Jerrel L. Yakel

Faculty Publications

Long-term memories are formed by creating stable memory representations via memory consolidation, which mainly occurs during sleep following the encoding of labile memories in the hippocampus during waking. The entorhinal cortex (EC) has intricate connections with the hippocampus, but its role in memory consolidation is largely unknown. Using cell-type- and input-specific in vivo neural activity recordings, here we show that the temporoammonic pathway neurons in the EC, which directly innervate the output area of the hippocampus, exhibit potent oscillatory activities during anesthesia and sleep. Using in vivo individual and populational neuronal activity recordings, we demonstrate that a subpopulation of the …

Does Grazing Winter Cereal Rye In Iowa, Usa, Make It Profitable?, A. Plastina, J. Acharya, F. M. Marcos, M. R. Parvej, M. A. Licht, A. E. Robertson

Faculty Publications

Unproven economic returns at the farm level are a major barrier to large-scale adoption of cover crops. The objective of this study was to evaluate the short-run private net returns to producers implementing a cereal rye (Secale cereale L.) cover crop preceding the no-till corn (Zea mays L.) phase of a US Midwest corn-soybean (Glycine max [L.] Merr.) rotation in an integrated crop and cow-calf operation. We used experimental agronomic data from six location-years in Iowa to estimate private net returns to cereal rye across alternative scenarios in a partial budget framework. Net returns in the absence of grazing averaged …

Directing The Stereoselectivity Of The Claisen Rearrangement To Form Cyclic Ketones With Full Substitution At The Α-Positions, Fatimat O. Badmus, Raju S. Thombal, Satish Chandra Philkhana, Joshua A. Malone, Christian E. Bailey, Estefania Armendariz-Gonzalez, Edward W. Mureka, Cale M. Locicero, Frank R. Fronczek, Rendy Kartika

Faculty Publications

We report an enantioselective synthesis of cyclic ketones with full substitutions at the α-positions in a highly diastereoselective manner. Our method is achieved by subjecting substrate motifs in 2-allyloxyenones to chiral organomagnesium reagents, which trigger the Claisen rearrangement upon direct 1,2-carbonyl addition. The observed diastereoselectivity of the allyl migration is proposed to originate from the intramolecular chelation of the magnesium alkoxide to the allyloxy moiety.

Establishment Of A Birth-To-Education Cohort Of 1 Million Palestinian Refugees Using Electronic Medical Records And Electronic Education Records, Zeina Jamaluddine, Akihiro Seita, Ghada Ballout, Hussam Al-Fudoli, Gloria Paolucci, Shatha Albaik, Rami Ibrahim, Miho Sato, Hala Ghattas Ph.D., Oona M.R. Campbell

Faculty Publications

Introduction

By linking datasets, electronic records can be used to build large birth-cohorts, enabling researchers to cost-effectively answer questions relevant to populations over the life-course. Currently, around 5.8 million Palestinian refugees live in five settings: Jordan, Lebanon, Syria, West Bank, and Gaza Strip. The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) provides them with free primary health and elementary-school services. It maintains electronic records to do so.

We aimed to establish a birth cohort of Palestinian refugees born between 1st January 2010 and 31st December 2020 living in five settings by linking mother …

Nano-Injection Molding With Resin Mold Inserts For Prototyping Of Nanofluidic Devices For Single Molecular Detection, Farhad Shiri, Junseo Choi, Chad Vietz, Chathurika Rathnayaka, Anishkumar Manoharan, Suresh Shivanka, Guoqiang Li, Chengbin Yu, Michael C. Murphy, Steven A. Soper, Sunggook Park

Faculty Publications

While injection molding is becoming the fabrication modality of choice for high-scale production of microfluidic devices, especially those used for in vitro diagnostics, its translation into the growing area of nanofluidics (structures with at least one dimension <100 >nm) has not been well established. Another prevailing issue with injection molding is the high startup costs and the relatively long time between device iterations making it in many cases impractical for device prototyping. We report, for the first time, functional nanofluidic devices with dimensions of critical structures below 30 nm fabricated by injection molding for the manipulation, identification, and detection of single …

Physiological Arousal, Attentiveness, Emotion, And Word Retrieval In Aphasia: Effects And Relationships, Tyson G. Harmon, Angela Johnson, Vivian Ward, Shawn Nissen

Faculty Publications

Purpose: To (a) compare physiological arousal and attentiveness during a confrontational naming task between participants with aphasia and a control group across four conditions that varied according to emotionality of presented stimuli and (b) explore relationships among physiological arousal, attentiveness, perceived arousal, and naming performance. We hypothesized that participants with aphasia would show lower levels of arousal and attentiveness than control participants and that emotional conditions would lead to increased physiological arousal and attentiveness.

Method: Eight participants with aphasia and 15 control participants completed a confrontational naming task under positive, negative, and neutral conditions and rated their perceived arousal after …

Telling Stories In Noise: The Impact Of Background Noises On Spoken Language For People With Aphasia, Tyson G. Harmon, Brenna Scadden Nelson, Christopher Dromey, Kirsten Dixon Clawson

Faculty Publications

Purpose: Determine how different background noise conditions affect the spoken language of participants with aphasia during a story retell task.

Method: Participants included 11 adults with mild to moderate aphasia and 11 age- and gender-matched controls. Participants retold stories in a silent baseline and five background noise conditions (conversation, monologue, phone call, cocktail, pink noise). Dependent measures of speech acoustics (fundamental frequency, mean intensity), speech fluency (speech rate, disfluent words), and language production (correct information units, lexical errors, lexical diversity, and cohesive utterances) were compared between groups and across conditions.

Results: Background noise resulted in higher fundamental frequency (F_{0 …}

Ready Worker One? High-Res Vr For The Home Office, Anastasia Ruvimova, Felipe Fronchetti, Boden A. Kahn, Luiz Henrique Susin, Zekeya Hurley, Thomas Fritz, Mark Hancock, David Shepherd

Faculty Publications

Many employees prefer to work from home, yet struggle to squeeze their office into an already fully-utilized space. Virtual Reality (VR) seemingly offered a solution with its ability to transform even modest physical spaces into spacious, productive virtual offices, but hardware challenges - such as low resolution - have prevented this from becoming a reality. Now that hardware issues are being overcome, we are able to investigate the suitability of VR for daily work. To do so, we (1) studied the physical space that users typically dedicate to home offices and (2) conducted an exploratory study of users working in …

Building A Culture Of Scholarship With New Clinical Teachers By Writing About Social Justice Lawyering, Caroline Wick, Susan Bennett, Binny Miller, Michelle Assad, Maria Dooner, Mariam Hinds, Jessica Millward, Citalli Ochoa, Charles Ross, Anne Schaufele

Faculty Publications

This Article is a collection of essays about teaching social justice lawyering, as seen through the eyes of eight practitioners-in-residence in the clinical program at American University’s Washington College of Law (“WCL”). They include: Michelle Assad, Maria Dooner, Mariam Hinds, Jessica Millward, Citlalli Ochoa, Charles Ross, Anne Schaufele, and Caroline Wick. They teach in seven clinics, including the Civil Advocacy Clinic, the Criminal Justice Clinic, the Community Economic and Equity Development Clinic, the Disability Rights Law Clinic, the Immigrant Justice Clinic, the International Human Rights Law Clinic, and the Janet R. Spragens Federal Income Tax Clinic. We use the terms …

Class Size Determination And Decision Making In Lis Online Education, Lucy Santos Green, Kim M. Thompson, Nicole A. Cooke

Faculty Publications

The purpose of this study was to develop a national landscape of the decisions made by LIS programs regarding online course enrollment caps. Online education expands learning opportunities for all students and is particularly attractive to nontraditional students who are more likely to have employment and family obligations that make attending traditional face-to-face classes difficult. At the same time, online learning can exacerbate existing opportunity gaps between certain student groups, depending on how well-prepared students are for online learning. This survey methodology study investigated course enrollment caps and the reasons behind the limits placed by Master of Library and Information …

Regional Variation In The Trophic Ecology Of Wahoo (Acanthocybium Solandri) In The Western Atlantic Ocean, Brendan Gough, Alexandra Prouse, Michael A. Dance, R. J.David Wells, Jay R. Rooker

Faculty Publications

Intrinsic tracers, such as stable isotopes of carbon and nitrogen, are common dietary markers that accumulate in the muscle tissue of consumers and can be used to determine the dietary sources and trophic positions of consumers. The aim of this study was to assess regional variation in the trophic ecology of wahoo (Acanthocybium solandri) using bulk stable isotopes. Muscle biopsies of wahoo were collected from four regions in the western Atlantic Ocean: the eastern Gulf of Mexico, western Gulf of Mexico, Northwest Atlantic Ocean, and Caribbean Sea. Muscle tissue δ¹³C and δ¹⁵N values for wahoo ranged …

Need-Oriented Evangelism: Encountering, Embracing, And Experiencing God, Petr Cincala, Allison Sauceda

Faculty Publications

This article provides a fresh perspective on evangelism by reflecting a belief in the Triune God--the source of saving truth and loving community. Mission is part of God’s nature; he is the ultimate Missionary. Mission happens naturally whenever children of God intentionally invite and facilitate God’s presence. Over time, the word “evangelism" has become contaminated by myths, a false understanding of God, and unpleasant religious experiences and practices. Genuine evangelism addresses the most burning issues of people’s lives and should be treated as such. True evangelism involves caring about, praying for, and sharing with people. The practical part of this …

White Adipose Tissue Heterogeneity In The Single-Cell Era: From Mice And Humans To Cattle, Hunter Ford, Qianglin Liu, Xing Fu, Clarissa Strieder-Barboza

Faculty Publications

Adipose tissue is a major modulator of metabolic function by regulating energy storage and by acting as an endocrine organ through the secretion of adipokines. With the advantage of next-generation sequencing-based single-cell technologies, adipose tissue has been studied at single-cell resolution, thus providing unbiased insight into its molecular composition. Recent single-cell RNA sequencing studies in human and mouse models have dissected the transcriptional cellular heterogeneity of subcutaneous (SAT), visceral (VAT), and intramuscular (IMAT) white adipose tissue depots and revealed unique populations of adipose tissue progenitor cells, mature adipocytes, immune cell, vascular cells, and mesothelial cells that play direct roles on …