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The Utility Of Single Nucleotide Polymorphisms In Inferences Of Population History, Robb T. Brumfield, Peter Beerli, Deborah A. Nickerson, Scott V. Edwards May 2003

The Utility Of Single Nucleotide Polymorphisms In Inferences Of Population History, Robb T. Brumfield, Peter Beerli, Deborah A. Nickerson, Scott V. Edwards

Faculty Publications

Single nucleotide polymorphisms (SNPs) represent the most widespread type of sequence variation in genomes, yet they have only emerged recently as valuable genetic markers for revealing the evolutionary history of populations. Their occurrence throughout the genome also makes them ideal for analyses of speciation and historical demography, especially in light of recent theory suggesting that many unlinked nuclear loci are needed to estimate population genetic parameters with statistical confidence. In spite of having lower variation compared with microsatellites, SNPs should make the comparison of genomic diversities and histories of different species (the core goal of comparative biogeography) more straightforward than …

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Comparison Of Written And Oral Examinations In A Baccalaureate Medical-Surgical, Patricia Rushton, Dennis L. Eggett May 2003

Comparison Of Written And Oral Examinations In A Baccalaureate Medical-Surgical, Patricia Rushton, Dennis L. Eggett

Faculty Publications

Nursing students traditionally have been evaluated with an objective written examination. This method has shown some benefits and disadvantages. This project examined the value of oral examinations in evaluating nursing students. Five groups of students were evaluated with different forms of testing, some with only written tests, others with only oral examinations, some with a combination of both types of evaluations. The results showed that oral examinations can effectively evaluate the student's comprehension and application of clinical information in a clinical situation, as shown in higher test results, compared with oral written examinations, and positive student comments. Oral examination can …

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Measurement Of High-Q2 E- P Neutral Current Cross Sections At Hera And The Extraction Of Xf3: The Zeus Collaboration, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch, I. Brock May 2003

Measurement Of High-Q2 E- P Neutral Current Cross Sections At Hera And The Extraction Of Xf3: The Zeus Collaboration, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch, I. Brock

Faculty Publications

Cross sections for e- p neutral current deep inelastic scattering have been measured at a centre-of-mass energy of 318 GeV using an integrated luminosity of 15.9 pb-1 collected with the ZEUS detector at HERA. Results on the double-differential cross-section d2σ/dx dQ2 in the range 185 < Q2 < 50 000 GeV2 and 0.0037 < x < 0.75, as well as the single-differential cross-sections dσ/dQ2, dσ/dx and dσ/dy for Q2 > 200GeV2, are presented. To study the effect of Z-boson exchange, dσ/dx has also been measured for Q2 > 10 000 GeV2. The structure function xF3 has been extracted by combining the e-p results presented here with the recent ZEUS measurements of e+ p neutral current deep inelastic scattering. All results agree well with the predictions of …

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Enabling Remote Access To Personal Electronic Medical Records, James K. Archibald, Eric S. Hall, Charles D. Knutson, David K. Vawdrey May 2003

Enabling Remote Access To Personal Electronic Medical Records, James K. Archibald, Eric S. Hall, Charles D. Knutson, David K. Vawdrey

Faculty Publications

Millions of people suffer from medical conditions that should be made known to healthcare practitioners prior to treatment. Paramedics and emergency room doctors cannot provide optimal care without sufficient knowledge of a patient’s medical history. Lacking patient information such as allergies, current prescriptions, and preexisting conditions, medical professionals are often forced to either delay treatment or rely on instincts. Medical mistakes in situations like these kill thousands of people and cost an estimated US$37 billion each year in the United States [1]. With the advent of electronic medical records (EMRs), patient information can be stored in computer databases at hospitals …

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Toward A Better Understanding Of The Comparatively High Prostate Cancer Incidence Rates In Utah, Ray M. Merrill, Sterling C. Hilton, Jared D. Sturgeon, Charles L. Wiggins Apr 2003

Toward A Better Understanding Of The Comparatively High Prostate Cancer Incidence Rates In Utah, Ray M. Merrill, Sterling C. Hilton, Jared D. Sturgeon, Charles L. Wiggins

Faculty Publications

This study assesses whether comparatively high prostate cancer incidence rates among white men in Utah represent higher rates among members of the Church of Jesus Christ of Latter-day Saints (LDS or Mormons), who comprise about 70% of the state's male population, and considers the potential influence screening has on these rates. Methods: Analyses are based on 14,693 histologically confirmed invasive prostate cancer cases among men aged 50 years and older identified through the Utah Cancer Registry between 1985 and 1999. Cancer records were linked to LDS Church membership records to determine LDS status. Poisson regression was used to derive rate …

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Racial Attitudes Among South African Young Adults: A Four-Year Follow-Up Study, Timothy B. Smith, Christopher R. Stones, Anthony Naidoo Apr 2003

Racial Attitudes Among South African Young Adults: A Four-Year Follow-Up Study, Timothy B. Smith, Christopher R. Stones, Anthony Naidoo

Faculty Publications

Due to many social changes that have occurred in South Africa since the first democratic elections in 1994, careful scrutiny must be given to the racial attitudes of South Africa’s young adults. Their degree of acceptance of the doctrine of deracialisation and reconciliation represents a hope or a warning in regard to a stable future. A follow up study was thus carried out in order to update data collected in 1995, with the hypothesis that, over time, greater acceptance of other racial groups would be reported. The authors examined the differences among the 180 Xhosa-speaking black, 89 so-called coloured, and …

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Valuation Of Continuous And Intermittent Phragmites Control, R. Eugene Turner, R. S. Warren Apr 2003

Valuation Of Continuous And Intermittent Phragmites Control, R. Eugene Turner, R. S. Warren

Faculty Publications

Quantifying the relative value of Phragmites australis and Spartina alterniflora habitat is important to evaluate the benefits and risks of different attempts to address Phragmites expansion on the U.S. eastern seaboard. Two contrasting approaches commonly used to restore tidal marsh habitats invaded by Phragmites communities involve spraying Phragmites with herbicide only when its coverage of a particular marsh area is near or close to 100%. Alternatively, after the first application, herbicide is annually applied on any surviving patches of Phragmites present in a mosaic of other marsh vegetation. A model is introduced to evaluate the relative habitat value of these …

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Genetic Organization And Iron-Responsive Regulation Of The Brucella Abortus 2,3-Dihydroxybenzoic Acid Biosynthesis Operon, A Cluster Of Genes Required For Wild-Type Virulence In Pregnant Cattle, Bryan H. Bellaire, Philip H. Elzer, Sue Hagius, Joel Walker, Cynthia L. Baldwin, R. Martin Roop Apr 2003

Genetic Organization And Iron-Responsive Regulation Of The Brucella Abortus 2,3-Dihydroxybenzoic Acid Biosynthesis Operon, A Cluster Of Genes Required For Wild-Type Virulence In Pregnant Cattle, Bryan H. Bellaire, Philip H. Elzer, Sue Hagius, Joel Walker, Cynthia L. Baldwin, R. Martin Roop

Faculty Publications

Brucella abortus reportedly produces the monocatechol siderophore 2,3-dihydroxybenzoic acid (2,3-DHBA) in response to iron limitation. Nucleotide sequence analysis of the cloned DHBA biosynthesis locus from virulent B. abortus 2308 and genetic complementation of defined Escherichia coli mutants were used to identify the B. abortus genes (designated dhbC, -B, and -A) responsible for synthesis of this siderophore. Reverse transcriptase PCR analysis of total RNA with dhb-specific primers demonstrated that dhbC, -B, and -A are transcribed as components of an operon, together with dhbE, a functional homolog of the Escherichia coli entE gene. Homologs of the E. coli entD and Vibrio cholerae …

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First Options, Consent To Arbitration, And The Demise Of Separability: Restoring Access To Justice For Contracts With Arbitration Provisions, Richard C. Reuben Apr 2003

First Options, Consent To Arbitration, And The Demise Of Separability: Restoring Access To Justice For Contracts With Arbitration Provisions, Richard C. Reuben

Faculty Publications

This article describes the context and current state of the law in this area under the Federal Arbitration Act (FAA), urges the Court to continue its path toward actual consent to arbitration, and suggests an approach for finally reconciling the tension between Prima Paint and First Options. Part II describes the nature and historical context of the arbitrability problem. Part III focuses specifically on the doctrine of separability, which is the most critical (and most complex) of these exceptions. Part IV discusses the impact on separability of recent U.S. Supreme Court case law, especially the 1995 decision in First Options …

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Y Chromosome Str Haplotypes And The Genetic Structures Of U.S. Populations Of African, European, And Hispanic Ancestry, Manfred Kayser, Silke Brauer, Hiltrud Schädlich, Mechthild Prinz, Mark A. Batzer, Peter A. Zimmerman, B. A. Boatin, Mark Stoneking Apr 2003

Y Chromosome Str Haplotypes And The Genetic Structures Of U.S. Populations Of African, European, And Hispanic Ancestry, Manfred Kayser, Silke Brauer, Hiltrud Schädlich, Mechthild Prinz, Mark A. Batzer, Peter A. Zimmerman, B. A. Boatin, Mark Stoneking

Faculty Publications

To investigate geographic structure within U.S. ethnic populations, we analyzed 1705 haplotypes on the basis of 9 short tandem repeat (STR) loci on the Y-chromosome from 9-11 groups each of African-Americans, European-Americans, and Hispanics. There were no significant differences in the distribution of Y-STR haplotypes among African-American groups, whereas European-American and Hispanic groups did exhibit significant geographic heterogeneity. However, the significant heterogeneity resulted from one sample; removal of that sample in each case eliminated the significant heterogeneity. Multidimensional scaling analysis of RST values indicated that African-American groups formed a distinct cluster, whereas there was some intermingling of European-American and Hispanic …

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American Indian Doctorate Receipt 1980-2000: A Quantitative And Qualitative Analysis, Timothy Lintner Apr 2003

American Indian Doctorate Receipt 1980-2000: A Quantitative And Qualitative Analysis, Timothy Lintner

Faculty Publications

This research presents a quantitative and qualitative analysis of American Indian doctorate receipt between 1980-2000. A quantitative analysis of American Indian doctorate receipt by sex and by broadfield category is initially presented. This research also sought to qualitatively explore the multiple factors that influence American Indians to receive and utilize their doctorate in the field of Education. Interviews with 16 American Indian doctorate recipients in the field of Education from the University of Oklahoma, the University of Arizona, and Northern Arizona University were conducted. Findings revealed that issues of community, personal and professional interest, and voice and access were all …

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Remembering Andrew I. Batavia, Michael Ashley Stein Apr 2003

Remembering Andrew I. Batavia, Michael Ashley Stein

Faculty Publications

No abstract provided.

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The Economic Ambiguity (And Possible Irrelevance) Of Tax Transition Rules, Eric D. Chason Apr 2003

The Economic Ambiguity (And Possible Irrelevance) Of Tax Transition Rules, Eric D. Chason

Faculty Publications

No abstract provided.

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Approving Employee Retention And Severance Programs Judicial Discretion Run Amuck, A. Mechele Dickerson Apr 2003

Approving Employee Retention And Severance Programs Judicial Discretion Run Amuck, A. Mechele Dickerson

Faculty Publications

No abstract provided.

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Measurement Of Event Shapes In Deep Inelastic Scattering At Hera, S. Chekanov, D. Krakauer, J. H. Loizides, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch Apr 2003

Measurement Of Event Shapes In Deep Inelastic Scattering At Hera, S. Chekanov, D. Krakauer, J. H. Loizides, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch

Faculty Publications

Inclusive event-shape variables have been measured in the current region of the Breit frame for neutral current deep inelastic ep scattering using an integrated luminosity of 45.0 pb-1 collected with the ZEUS detector at HERA. The variables studied included thrust, jet broadening and invariant jet mass. The kinematic range covered was 10 < Q2 < 20480 GeV2 and 6 × 10-4 < x < 0.6, where Q2 is the virtuality of the exchanged boson and x is the Bjorken variable. The Q dependence of the shape variables has been used in conjunction with NLO perturbative calculations and the Dokshitzer-Webber non-perturbative corrections ('power corrections') to investigate the validity of this approach.

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Taming The Tyranny Of Too Much, H. Peter Swanson Apr 2003

Taming The Tyranny Of Too Much, H. Peter Swanson

Faculty Publications

No abstract provided.

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Transmission Of Mycobacterium Tuberculosis Associated With Failed Completion Of Treatment For Latent Tuberculosis Infection - Chickasaw County, Mississippi, June 1999-March 2002, T. Chamblee, D. Hartley, M. Holcombe, K. Parham, P. Upchurch, R. M. Webb, Alyssa G. Robillard, L. Diem, B. Metchock, N. Deluca, P. D. Mcelroy, T. Navin, W. Walton, P. K. Dewan Mar 2003

Transmission Of Mycobacterium Tuberculosis Associated With Failed Completion Of Treatment For Latent Tuberculosis Infection - Chickasaw County, Mississippi, June 1999-March 2002, T. Chamblee, D. Hartley, M. Holcombe, K. Parham, P. Upchurch, R. M. Webb, Alyssa G. Robillard, L. Diem, B. Metchock, N. Deluca, P. D. Mcelroy, T. Navin, W. Walton, P. K. Dewan

Faculty Publications

During June 1999-March 2002, a total of 16 tuberculosis (TB) cases were reported from Chickasaw County, Mississippi (2000 population: 19,440), corresponding to annual TB incidences of 20.5-27.6 cases per 100,000 population. In comparison, annual TB incidences for Mississippi during the same period decreased from 7.8 to 5.4 cases per 100,000 population. This report summarizes the results of an investigation of the patients and their contacts and demonstrates the need for strategies to increase the proportion of infection contacts that successfully complete treatment for latent TB infection (LTBI).

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A Causative Relationship Exists Between Eosinophils And The Development Of Allergic Pulmonary Pathologies In The Mouse, Hua Hao H. Shen, Sergei I. Ochkur, Michael P. Mcgarry, Jeffrey R. Crosby, Edie M. Hines, Michael T. Borchers, Huiying Wang, Travis L. Biechelle, Katie R. O'Neill, Tracy L. Ansay, Dana C. Colbert, Stephania A. Cormier, J. Paul Justice, Nancy A. Lee, James J. Lee Mar 2003

A Causative Relationship Exists Between Eosinophils And The Development Of Allergic Pulmonary Pathologies In The Mouse, Hua Hao H. Shen, Sergei I. Ochkur, Michael P. Mcgarry, Jeffrey R. Crosby, Edie M. Hines, Michael T. Borchers, Huiying Wang, Travis L. Biechelle, Katie R. O'Neill, Tracy L. Ansay, Dana C. Colbert, Stephania A. Cormier, J. Paul Justice, Nancy A. Lee, James J. Lee

Faculty Publications

Asthma and mouse models of allergic respiratory inflammation are invariably associated with a pulmonary eosinophilia; however, this association has remained correlative. In this report, a causative relationship between eosinophils and allergen-provoked pathologies was established using eosinophil adoptive transfer. Eosinophils were transferred directly into the lungs of either naive or OVA-treated IL-5-/- mice. This strategy resulted in a pulmonary eosinophilia equivalent to that observed in OVA-treated wild-type animals. A concomitant consequence of this eosinophil transfer was an increase in Th2 bronchoalveolar lavage cytokine levels and the restoration of intracellular epithelial mucus in OVA-treated IL-5-/- mice equivalent to OVA-treated wild-type levels. Moreover, …

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Stabilizing The Open Conformation Of The Integrin Headpiece With A Glycan Wedge Increases Affinity For Ligand, Bing Hao Luo, Timothy A. Springer, Junichi Takagi Mar 2003

Stabilizing The Open Conformation Of The Integrin Headpiece With A Glycan Wedge Increases Affinity For Ligand, Bing Hao Luo, Timothy A. Springer, Junichi Takagi

Faculty Publications

The affinity of the extracellular domain of integrins for ligand is regulated by conformational changes signaled from the cytoplasm. Alternative types of conformational movement in the ligandbinding headpiece have been proposed. In one study, electron micrograph image averages of the headpiece of integrin aVβ3 show two different conformations. The open conformation of the headpiece is present when a ligand mimetic peptide is bound and differs from the closed conformation in the presence of an obtuse angle between the β3 subunit hybrid and I-like domains. We tested the hypothesis that opening of the hybrid-I-like domain interface increases ligand-binding affinity by mutationally …

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Bacillus Anthracis Virulence In Guinea Pigs Vaccinated With Anthrax Vaccine Adsorbed Is Linked To Plasmid Quantities And Clonality, Pamala R. Coker, Kimothy L. Smith, Patricia F. Fellows, Galena Rybachuck, Konstantin G. Kousoulas, Martin E. Hugh-Jones Mar 2003

Bacillus Anthracis Virulence In Guinea Pigs Vaccinated With Anthrax Vaccine Adsorbed Is Linked To Plasmid Quantities And Clonality, Pamala R. Coker, Kimothy L. Smith, Patricia F. Fellows, Galena Rybachuck, Konstantin G. Kousoulas, Martin E. Hugh-Jones

Faculty Publications

Bacillus anthracis is a bacterial pathogen of great importance, both historically and in the present. This study presents data collected from several investigations and indicates that B. anthracis virulence is associated with the clonality and virulence of plasmids pXO1 and pXO2. Guinea pigs vaccinated with Anthrax Vaccine Adsorbed were challenged with 20 B. anthracis isolates representative of worldwide genetic diversity. These same isolates were characterized with respect to plasmid copy number by using a novel method of quantitative PCR developed for rapid and efficient detection of B. anthracis from environmental samples. We found that the copy numbers for both pXO1 …

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Human Population Genetic Structure And Inference Of Group Membership, Michael J. Bamshad, Stephen Wooding, W. Scott Watkins, Christopher T. Ostler, Mark A. Batzer, Lynn B. Jorde Mar 2003

Human Population Genetic Structure And Inference Of Group Membership, Michael J. Bamshad, Stephen Wooding, W. Scott Watkins, Christopher T. Ostler, Mark A. Batzer, Lynn B. Jorde

Faculty Publications

A major goal of biomedical research is to develop the capability to provide highly personalized health care. To do so, it is necessary to understand the distribution of interindividual genetic variation at loci underlying physical characteristics, disease susceptibility, and response to treatment. Variation at these loci commonly exhibits geographic structuring and may contribute to phenotypic differences between groups. Thus, in some situations, it may be important to consider these groups separately. Membership in these groups is commonly inferred by use of a proxy such as place-of-origin or ethnic affiliation. These inferences are frequently weakened, however, by use of surrogates, such …

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Combined Analysis Of Genomewide Scans For Adult Height: Results From The Nhlbi Family Blood Pressure Program, Xiaodong Wu, Richard S. Cooper, Eric Boerwinkle, Stephen T. Turner, Steve Hunt, Richard Myers, Richard A. Olshen, David Curb, Xiaofeng Zhu, Donghui Kan, Amy Luke Mar 2003

Combined Analysis Of Genomewide Scans For Adult Height: Results From The Nhlbi Family Blood Pressure Program, Xiaodong Wu, Richard S. Cooper, Eric Boerwinkle, Stephen T. Turner, Steve Hunt, Richard Myers, Richard A. Olshen, David Curb, Xiaofeng Zhu, Donghui Kan, Amy Luke

Faculty Publications

A combined analysis of genome scans was performed for adult height in the NHLBI Family Blood Pressure Program. Height data were available on 6752 individuals. Linkage analysis was performed first separately for each of the eight ethnic groups in the four networks using the variance component method. To increase the power to detect the common genetic components affecting height for all the individuals, a linkage analysis was performed subsequently for the combined data set by pooling the average allele-sharing IBD () for all groups. By combining the data, we replicated evidence for a QTL influencing adult height on chromosome 7 …

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Measurements Of Inelastic J/Ψ And Ψ′ Photoproduction At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch, I. Brock Mar 2003

Measurements Of Inelastic J/Ψ And Ψ′ Photoproduction At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch, I. Brock

Faculty Publications

The cross sections for inelastic photoproduction of J/ψ and ψ′ mesons have been measured in ep collisions with the ZEUS detector at HERA, using an integrated luminosity of 38.0 pb-1. The events were required to have 0.1 < z < 0.9 and 50 < W < 180 GeV, where z is the fraction of the incident photon energy carried by the J/ψ in the proton rest frame and W is the photon-proton centre-of-mass energy. The ψ′ to J/ψ cross-section ratio was measured in the range 0.55 < z < 0.9. The J/ψ data, for various ranges of transverse momentum, are compared to theoretical models incorporating colour-singlet and colour-octet matrix elements. Predictions of a next-to-leading-order colour-singlet model give a good description of the data, although there is a large normalisation uncertainty. The J/ψ helicity distribution for z > 0.4 is compared to leading-order QCD predictions.

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Observation Of The Strange Sea In The Proton Via Inclusive Φ-Meson Production In Neutral Current Deep Inelastic Scattering At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch, I. Brock Feb 2003

Observation Of The Strange Sea In The Proton Via Inclusive Φ-Meson Production In Neutral Current Deep Inelastic Scattering At Hera, S. Chekanov, D. Krakauer, S. Magill, B. Musgrave, J. Repond, R. Yoshida, Margarita C. K. Mattingly, P. Antonioli, G. Bari, M. Basile, L. Bellagamba, D. Boscherini, A. Bruni, G. Bruni, G. Cara Romeo, L. Cifarelli, F. Cindolo, A. Contin, M. Corradi, S. De Pasquale, P. Giusti, G. Iacobucci, A. Margotti, R. Nania, F. Palmonari, A. Pesci, G. Sartorelli, A. Zichichi, G. Aghuzumtsyan, D. Bartsch, I. Brock

Faculty Publications

Inclusive φ(1020)-meson production in neutral current deep inelastic e+p scattering has been measured with the ZEUS detector at HERA using an integrated luminosity of 45 pb-1. The φ mesons were studied in the range 10 < Q2 < 100 GeV2, where Q2 is the virtuality of the exchanged photon, and in restricted kinematic regions in the transverse momentum, pT, pseudorapidity, η, and the scaled momentum in the Breit frame, xp. Monte Carlo models with the strangeness-suppression factor as determined by analyses of e+e- annihilation events overestimate the cross sections. A smaller value of the strangeness-suppression factor reduces the predicted cross sections, but fails to reproduce the shapes of the measured differential cross sections. High-momentum φ mesons in the current region of the Breit frame give the first direct evidence for the strange sea in the proton at low x. © 2002 Published by Elsevier Science B.V.

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Stat5a Promotes Adipogenesis In Nonprecursor Cells And Associates With The Glucocorticoid Receptor During Adipocyte Differentiation, Z. Elizabeth Floyd, Jacqueline M. Stephens Feb 2003

Stat5a Promotes Adipogenesis In Nonprecursor Cells And Associates With The Glucocorticoid Receptor During Adipocyte Differentiation, Z. Elizabeth Floyd, Jacqueline M. Stephens

Faculty Publications

The differentiation of adipocytes is regulated by the activity of a variety of transcription factors, including peroxidase proliferator-activated receptor (PPAR)-γ and C/EBPα. Our current study demonstrates that ectopic expression of STAT5A, such as that of PPAR-γ and C/EBPα, promotes adipogenesis in two nonprecursor fibroblast cell lines. Using morphologic and biochemical criteria, we have demonstrated that STAT5A and the combination of STAT5A and STAT5B are sufficient to induce the expression of early and late adipogenic markers in BALB/c and NIH-3T3 cells. Yet, the ectopic expression of STAT5B alone does not induce the expression of adipocyte genes, but enhances the induction of …

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A Meta-Analysis Of Genome-Wide Linkage Scans For Hypertension: The National Heart, Lung And Blood Institute Family Blood Pressure Program, Michael A. Province, Sharon L.R. Kardia, Koustubh Ranade, Dabeeru C. Rao, Bonnie A. Thiel, Richard S. Cooper, Neil Risch, Stephen T. Turner, David R. Cox, Steven C. Hunt, Alan B. Weder, Eric Boerwinkle Feb 2003

A Meta-Analysis Of Genome-Wide Linkage Scans For Hypertension: The National Heart, Lung And Blood Institute Family Blood Pressure Program, Michael A. Province, Sharon L.R. Kardia, Koustubh Ranade, Dabeeru C. Rao, Bonnie A. Thiel, Richard S. Cooper, Neil Risch, Stephen T. Turner, David R. Cox, Steven C. Hunt, Alan B. Weder, Eric Boerwinkle

Faculty Publications

Background: Four multicenter Networks (GenNet, GENOA, HyperGEN, SAPPHIRe) form the National Heart, Lung and Blood Institute Family Blood Pressure Program (FBPP), to search for hypertension/blood pressure (BP) genes. The networks used different family designs and targeted multiple ethnic groups, using standardized protocols and definitions. Linkage genome scans were done on samples within each network (N = 6245 relatives). Methods: The evidence was synthesized using meta-analysis. Results: Combining ethnic groups, no region reached LOD >2, but several small peaks were identified, including chromosome 2p where two other recent reports find hypertension linkage. Conclusions: No regions show uniformly large effects on BP/hypertension …

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Race, Genes, And Health - New Wine In Old Bottles?, Richard S. Cooper Feb 2003

Race, Genes, And Health - New Wine In Old Bottles?, Richard S. Cooper

Faculty Publications

No abstract provided.

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Dlist: Building An International Scholarly Communication Consortium For Library And Information Science, Anita Coleman, Paul Bracke Feb 2003

Dlist: Building An International Scholarly Communication Consortium For Library And Information Science, Anita Coleman, Paul Bracke

Faculty Publications

DLIST is the Digital Library of Information Science and Technology, a repository of electronic resources in the domains of Library and Information Science (LIS) and Information Technology (IT). Initial collection development scope is in Information Literacy and Informetrics. Academics, researchers, and practitioners create a wealth of content that includes published papers, instructional materials, tutorials for software and databases, bibliographies, pathfinders, bibliometric datasets, dissertations and reports. DLIST aims to capture this wealth of information in a library that is openly available for re-use and global dissemination. Open deposit processes where authors retain copyright and facilities for full-text storage in a variety …

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Onset Of Major Depressive Disorder Among Adolescents, John P. Hoffmann, Scott A. Baldwin, Felicia G. Cerbone Feb 2003

Onset Of Major Depressive Disorder Among Adolescents, John P. Hoffmann, Scott A. Baldwin, Felicia G. Cerbone

Faculty Publications

Objectives: To examine the association between parental affective disorders and psychoactive substance use disor- ders and the onset of major depressive disorder (MDD) among adolescents and young adults and to determine whether this association is affected by stressful life events, family cohesion, self-esteem, or gender. Method: Prospective cohort study of 804 adolescents, aged 11–17 years, and their parents who were followed for seven consecutive years. The sam- ple was drawn from the Minneapolis-St. Paul metropolitan area. Parental diagnoses were based on Structured Clinical Interview for DSM-III-R administered during study screening stage. Diagnoses of MDD and age of onset were based …

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Utilization Of Algal And Bacterial Extracellular Polymeric Secretions (Eps) By The Deposit-Feeding Brittlestar Amphipholis Gracillima (Echinodermata), D. L. Hoskins, S. E. Stancyk, Alan W. Decho Feb 2003

Utilization Of Algal And Bacterial Extracellular Polymeric Secretions (Eps) By The Deposit-Feeding Brittlestar Amphipholis Gracillima (Echinodermata), D. L. Hoskins, S. E. Stancyk, Alan W. Decho

Faculty Publications

Like many deposit-feeding organisms, the burrowing brittlestar Amphipholis gracillima feeds on particulate organic matter in surface sediments. Microbial exopolymeric secretions (EPS) are carbohydrate-enriched polymers produced by microalgae and bacteria that bind aggregates and form dense biofilms near the sediment-water interface. EPS are assimilable by some benthic infauna and may be utilized as a significant carbon source. EPS are absorbed by some deposit-feeders, including a holothurian, and may be supplemental sources of nutrition. The burrowing brittlestar A. gracillima is a deposit-feeder that was used in a mass balance approach to model the incorporation of radiolabeled EPS by bottom feeders. Brittlestars were …

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