Digital Commons Network^™

Compatibility Or Restraint? The Effects Of Sexual Timing On Marriage Relationships, Dean M. Busby, Jason S. Carroll, Brian J. Willoughby

Faculty Publications

Very little is known about the influence of sexual timing on relationship outcomes. Is it better to test sexual compatibility as early as possible or show sexual restraint so that other areas of the relationship can develop? In this study, we explore this question with a sample of 2035 married individuals by examining how soon they became sexually involved as a couple and how this timing is related to their current sexual quality, relationship communication, and relationship satisfaction and perceived stability. Both structural equation and group comparison analyses demonstrated that sexual restraint was associated with better relationship outcomes, even when …

Social Relationships And Mortality Risk: A Meta-Analytic Review, Julianne Holt-Lunstad

Faculty Publications

Background

The quality and quantity of individuals' social relationships has been linked not only to mental health but also to both morbidity and mortality.

Objectives

This meta-analytic review was conducted to determine the extent to which social relationships influence risk for mortality, which aspects of social relationships are most highly predictive, and which factors may moderate the risk.

Data Extraction

Data were extracted on several participant characteristics, including cause of mortality, initial health status, and pre-existing health conditions, as well as on study characteristics, including length of follow-up and type of assessment of social relationships.

Results

Across 148 studies (308,849 …

Invocations And Intoxication: Does Prayer Decrease Alcohol Consumption?, Nathaniel M. Lambert, Frank D. Fincham, Loren D. Marks, Tyler F. Stillman

Faculty Publications

Four methodologically diverse studies (N = 1,758) show that prayer frequency and alcohol consumption are negatively related. In Study 1 (n = 824), we used a cross-sectional design and found that higher prayer frequency was related to lower alcohol consumption and problematic drinking behavior. Study 2 (n = 702) used a longitudinal design and found that more frequent prayer at Time 1 predicted less alcohol consumption and problematic drinking behavior at Time 2, and this relationship held when controlling for baseline levels oof drinking and prayer. In Study 3 (n = 117), we used an experimental …

Perspectives Of Fitness And Health In College Men And Women, Jennifer J. Waldron, Rodney B. Dieser

Faculty Publications

Because many college students engage in low levels of physical activity, the current study used a qualitative framework to interview 11 college students to examine the meaning physically active college students assign to the practice of fitness and health. Students discussed the importance of healthy eating, but that it was difficult to accomplish at college. Additionally, students intertwined health and fitness with physical appearance and attractiveness. In particular, the media shaped many of their perceptions of health and fitness. Implications of these findings to policy making in higher education, in particular wellness programming, are highlighted.

Structural Health Monitoring With Piezoelectric Wafer Active Sensors—Predictive Modeling And Simulation, Victor Giurgiutiu

Faculty Publications

This paper starts a review of the state of the art in structural health monitoring with piezoelectric wafer active sensors and follows with highlighting the limitations of the current approaches which are predominantly experimental. Subsequently, the paper examines the needs for developing a predictive modeling methodology that would allow to perform extensive parameter studies to determine the sensing method’s sensitivity to damage and insensitivity to confounding factors such as environmental changes, vibrations, and structural manufacturing variability. The thesis is made that such a predictive methodology should be multi-scale and multi-domain, thus encompassing the modeling of structure, sensors, electronics, and power …

Structural Health Monitoring With Piezoelectric Wafer Active Sensors--Predictive Modeling And Simulation, Victor Giurgiutiu

Faculty Publications

This paper starts a review of the state of the art in structural health monitoring with piezoelectric wafer active sensors and follows with highlighting the limitations of the current approaches which are predominantly experimental. Subsequently, the paper examines the needs for developing a predictive modeling methodology that would allow to perform extensive parameter studies to determine the sensing method’s sensitivity to damage and insensitivity to confounding factors such as environmental changes, vibrations, and structural manufacturing variability. The thesis is made that such a predictive methodology should be multi-scale and multi-domain, thus encompassing the modeling of structure, sensors, electronics, and power …

Madaba Plains Project-Tall Jalul 2009, Paul Z. Gregor, Constance E. Gane, Randall Younker, Paul Ray, Karen Borstad, Theodore W. Burgh, Roy Gane, Jennifer Groves, Reem Al Shquor

Faculty Publications

No abstract provided.

Metabolic Actions Of Insulin In Men And Women, Faidon Magkos, Xuewen Wang, Bettina Mittendorfer

Faculty Publications

Insulin is an important regulator of glucose, lipid and protein metabolism. It suppresses hepatic glucose and triglyceride production, inhibits adipose tissue lipolysis and whole-body and muscle proteolysis and stimulates glucose uptake in muscle. In this review we discuss what is currently known about the control of substrate metabolism by insulin in men and women. The data available so far indicate that women are more sensitive to insulin with regards to glucose metabolism (both in the liver and in muscle) whereas there are no differences between men and women in insulin action on lipolysis. Potential differences exist in the regulation of …

Racial Disparities Between The Sex Steroid Milieu And The Metabolic Risk Profile, Arlette C. Perry, Xuewen Wang, Ronald B. Goldberg, Robert Ross, Loreto Jackson

Faculty Publications

Aims and Method. The present study examined the relationship between the metabolic risk profile (MRP) and total testosterone (TT) and free testosterone using the free androgen index (FAI) and sex hormone binding globulin (SHBG) in 36 Caucasian American (CA) and 30 African-American (AA) women volunteering for a weight loss study. Results. After controlling for age, significant relationships were found between TT and diastolic blood pressure (P = .004 and P = .015 in CA and AA women, resp.). Additionally, total cholesterol (P = .003), low density lipoprotein cholesterol (P = .004), apolipoprotein B (P = .006), …

Isaiah 53, Substitution, And The Covenant Curses—Part 2, Richard M. Davidson

Faculty Publications

No abstract provided.

Trends In Body Fat, Body Mass Index And Physical Fitness Among Male And Female College Students, Peter Pribis, Carol A. Burtnack, Sonya O. Mckenzie, Jerome Thayer

Faculty Publications

There have been many publications in recent years reporting on the quantity of physical activity among college students using indirect indicators such as steps walked per day or time spent on physical activities. The purpose of this study was to describe the trends of physical fitness related to BMI and body fat among university students between 1996 and 2008. The results showed a significant decline in the average fitness levels measured as an estimation of VO2max for male and female students (p < 0.001 for both sexes). The linear trend for BMI by years was not significant for both sexes (p for males = 0.772, p for females = 0.253). On average, in the last 13 years, % body fat was increasing 0.513%/year for males and 0.654%/year for females. There is a significant indirect correlation between the student's VO2max levels and % body fat, r = -0.489; p < 0.001 for males; and r = -0.416, p < 0.001 for females. Approximately 23.9% of the variance in the VO2max levels in males and 17.3% in females can be explained by the variance in % body fat. The results support recent findings that physical fitness among college students is declining and body fatness is increasing. © 2010 by the authors.

Revolution In Pragmatist Clothing: Nationalizing Workplace Law, Jeffrey M. Hirsch

Faculty Publications

No abstract provided.

The Environmental Role Of Agriculture In An Era Of Carbon Caps, Donald Thomas Hornstein

Faculty Publications

No abstract provided.

The Danger To Confidential Communications In The Mismatch Between The Fourth Amendment's "Reasonable Expectation Of Privacy" And The Confidentiality Of Evidentiary Privileges, Robert P. Mosteller, Kenneth S. Broun

Faculty Publications

No abstract provided.

Enabling Responsible Public Genomics, John M. Conley, Adam K. Doerr, Daniel B. Vorhaus

Faculty Publications

No abstract provided.

Reputation In A Networked World: Revisiting The Social Foundations Of Defamation Law, David S. Ardia

Faculty Publications

No abstract provided.

Medical Research Regulation After More Than Twenty-Five Years: Old Problems, New Challenges, And Regulatory Imbalance, Richard S. Saver

Faculty Publications

No abstract provided.

The Moral Politics Of Social Control: Political Culture And Ordinary Crime In Cuba, Deborah M. Weissman, Marsha Weissman

Faculty Publications

No abstract provided.

Relative Height And Weight Among Children And Adolescents Of Rural Southwestern Nigeria, Omolola Ayoola, Kara Ebersole, Olayemi O. Omotade, Bamidele O. Tayo, William R. Brieger, Kabiru Salami, Lara R. Dugas, Richard S. Cooper, Amy Luke

Faculty Publications

Background: There are few data describing the relative height and weight patterns of children and adolescents in rural Nigeria, despite a prevalence of stunting of over 38% among children younger than 5 years. Aim: The present study documented the height and weight patterns relative to international standards among children and adolescents aged 520 years in rural Nigeria. Subjects and methods: Children 520 years of age were enrolled from two rural villages. Height and weight were measured; body composition was estimated using bioelectrical impedance analysis. z-scores and centiles for height and body mass index were calculated; prevalences of low relative height …

Near-Infrared Fluorescent Nanogumbos For Biomedical Imaging, David K. Bwambok, Bilal El-Zahab, Santhosh K. Challa, Min Li, Lin Chandler, Gary A. Baker, Isiah M. Warner

Faculty Publications

Herein, we report on near-infrared (NIR) fluorescent nanoparticles generated from an emergent class of materials we refer to as a Group of Uniform Materials Based on Organic Salts (GUMBOS). GUMBOS are largely frozen ionic liquids, although the concept is more general and is also easily applied to solid ionic materials with melting points in excess of 100 °C. Nanoparticles based on GUMBOS (nanoGUMBOS) derived from a NIR fluorophore are prepared using a reprecipitation method and evaluated for in vivo fluorescence imaging. Due to their uniformity, single-step preparation, and composite nature, nanoGUMBOS help to resolve issues with dye leakage problems innate …

Use Of Supplementary Phenotype To Identify Additional Rheumatoid Arthritis Loci In A Linkage Analysis Of 342 Uk Affected Sibling Pair Families, Bamidele O. Tayo, Yulan Liang, Arpad Kelemen, Austin Miller, Maurizio Trevisan, Richard S. Cooper

Faculty Publications

Background: Although rheumatoid arthritis has been shown to have moderately strong genetic component, both linked loci identified in linkage analyses and susceptibility variants from association studies are short of adequately accounting for a comprehensive catalogue of the molecular factors underlying this complex disease. The objective of this study was to use supplementary phenotype based on cumulative hazard of rheumatoid arthritis to identify linkage evidence for new and additional rheumatoid arthritis loci in a genome-wide linkage analysis of 342 affected sibling pair families from the United Kingdom.Methods: Using proportional hazards model, we estimated cumulative hazard of rheumatoid arthritis and then used …

A Comparison Of The Wellbeing Of Orphans And Abandoned Children Ages 6–12 In Institutional And Community-Based Care Settings In 5 Less Wealthy Nations, Kathryn Whetten, Jan Ostermann, Rachel A. Whetten, Brian W. Pence, Karen O'Donnell, Lynne C. Messer, Nathan M. Thielman, The Positive Outcomes For Orphans (Pofo) Research Team

Faculty Publications

Background

Leaders are struggling to care for the estimated 143,000,000 orphans and millions more abandoned children worldwide. Global policy makers are advocating that institution-living orphans and abandoned children (OAC) be moved as quickly as possible to a residential family setting and that institutional care be used as a last resort. This analysis tests the hypothesis that institutional care for OAC aged 6–12 is associated with worse health and wellbeing than community residential care using conservative two-tail tests.

Methodology

The Positive Outcomes for Orphans (POFO) study employed two-stage random sampling survey methodology in 6 sites across 5 countries to identify 1,357 …

Deliberation Versus Dispute: The Impact Of Argumentative Discourse Goals On Learning And Reasoning In The Science Classroom, Mark Felton, Merce Garcia-Mila, Sandra Gilabert

Faculty Publications

Researchers in science education have converged on the view that argumentation can be an effective intervention for promoting knowledge construction in science classrooms.However, the impact of such interventions may be mediated by individuals’ task goals while arguing. In argumentative discourse, one can distinguish two overlapping but distinct kinds of activity: dispute and deliberation. In dispute the goal is to defend a conclusion by undermining alternatives, whereas in deliberation the goal is to arrive at a conclusion by contrasting alternatives. In this study, we examine the impact of these discourse goals on both content learning and argument quality in science.

Phylogeny Of The Macaques (Cercopithecidae: Macaca) Based On Alu Elements, Jing Li, Kyudong Han, Jinchuan Xing, Heui Soo Kim, Jeffrey Rogers, Oliver A. Ryder, Todd Disotell, Bisong Yue, Mark A. Batzer

Faculty Publications

Genus Macaca (Cercopithecidae: Papionini) is one of the most successful primate radiations. Despite previous studies on morphology and mitochondrial DNA analysis, a number of issues regarding the details of macaque evolution remain unsolved. Alu elements are a class of non-autonomous retroposons belonging to short interspersed elements that are specific to the primate lineage. Because retroposon insertions show very little homoplasy, and because the ancestral state (absence of the SINE) is known, Alu elements are useful genetic markers and have been utilized for analyzing primate phylogenentic relationships and human population genetic relationships. Using PCR display methodology, 298 new Alu insertions have …

Internal Priming: An Opportunistic Pathway For L1 And Alu Retrotransposition In Hominins, Deepa Srikanta, Shurjo K. Sen, Erin M. Conlin, Mark A. Batzer

Faculty Publications

Retrotransposons, specifically Alu and L1 elements, have been especially successful in their expansion throughout primate genomes. While most of these elements integrate through an endonuclease-mediated process termed target primed reverse transcription, a minority integrate using alternative methods. Here we present evidence for one such mechanism, which we term internal priming and demonstrate that loci integrating through this mechanism are qualitatively different from "classical" insertions. Previous examples of this mechanism are limited to cell culture assays, which show that reverse transcription can initiate upstream of the 3′ poly-A tail during retrotransposon integration. To detect whether this mechanism occurs in vivo as …

Applied Climate-Change Analysis: The Climate Wizard Tool, Evan H. Girvetz, Chris Zganjar, George T. Raber, Edwin P. Maurer, Peter Kareiva, Joshua J. Lawler

Faculty Publications

Background: Although the message of "global climate change'' is catalyzing international action, it is local and regional changes that directly affect people and ecosystems and are of immediate concern to scientists, managers, and policy makers. A major barrier preventing informed climate-change adaptation planning is the difficulty accessing, analyzing, and interpreting climate-change information. To address this problem, we developed a powerful, yet easy to use, web-based tool called Climate Wizard (http://ClimateWizard.org) that provides non-climate specialists with simple analyses and innovative graphical depictions for conveying how climate has and is projected to change within specific geographic areas throughout the world. Methodology/Principal Findings: …

Feature Selection And Classification Of Maqc-Ii Breast Cancer And Multiple Myeloma Microarray Gene Expression Data, Qingzhong Liu, Andrew H. Sung, Zhongxue Chen, Jianzhong Liu, Xudong Huang, Youping Deng

Faculty Publications

Microarray data has a high dimension of variables but available datasets usually have only a small number of samples, thereby making the study of such datasets interesting and challenging. In the task of analyzing microarray data for the purpose of, e.g., predicting gene-disease association, feature selection is very important because it provides a way to handle the high dimensionality by exploiting information redundancy induced by associations among genetic markers. Judicious feature selection in microarray data analysis can result in significant reduction of cost while maintaining or improving the classification or prediction accuracy of learning machines that are employed to sort …

Rfx2 Is A Candidate Downstream Amplifier Of A-Myb Regulation In Mouse Spermatogenesis, Gary C. Horvath, Malathi K. Kistler, Wilson Stephen Kistler

Faculty Publications

Background: Mammalian spermatogenesis involves formation of haploid cells from the male germline and then a complex morphological transformation to generate motile sperm. Focusing on meiotic prophase, some tissue-specific transcription factors are known (A-MYB) or suspected (RFX2) to play important roles in modulating gene expression in pachytene spermatocytes. The current work was initiated to identify both downstream and upstream regulatory connections for Rfx2.

Results: Searches of pachytene up-regulated genes identified high affinity RFX binding sites (X boxes) in promoter regions of several new genes: Adam5, Pdcl2, and Spag6. We confirmed a strong promoter-region X-box for Alf, a germ cell-specific variant of …

Yy1'S Dna-Binding Motifs In Mammalian Olfactory Receptor Genes, Christopher D. Faulk, Joomyeong Kim

Faculty Publications

Background: YY1 is an epigenetic regulator for a large number of mammalian genes. While performing genome-wide YY1 binding motif searches, we discovered that the olfactory receptor (OLFR) genes have an unusual cluster of YY1 binding sites within their coding regions. The statistical significance of this observation was further analyzed. Results: About 45% of the olfactory genes in the mouse have a range of 4-8 YY1 binding sites within their respective 1 kb coding regions. Statistical analyses indicate that this enrichment of YY1 motifs has likely been driven by unknown selection pressures at the DNA level, but not serendipitously by some …

Sphingosine-1-Phosphate Elicits Receptor-Dependent Calcium Signaling In Retinal Amacrine Cells, Scott Crousillac, Jeremy Colonna, Emily Mcmains, Jill Sayes Dewey, Evanna Gleason

Faculty Publications

Evidence is emerging indicating that sphingosine-1-phosphate (S1P) participates in signaling in the retina. To determine whether S1P might be involved in signaling in the inner retina specifically, we examine the effects of this sphingolipid on cultured retinal amacrine cells. Whole cell voltage-clamp recordings reveal that S1P activates a cation current that is dependent on signaling through Gi and phospholipase C. These observations are consistent with the involvement of members of the S1P receptor family of G-protein-coupled receptors in the production of the current. Immunocytochemistry and PCR amplification provide evidence for the expression of S1P1R and S1P3R in amacrine cells. The …