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Everyone Brings Something To The Table: A Culturally Sustaining Analysis Of Teacher Candidates’ Mixed Reality Teaching Simulations, Erin Scott Dec 2024

Everyone Brings Something To The Table: A Culturally Sustaining Analysis Of Teacher Candidates’ Mixed Reality Teaching Simulations, Erin Scott

Faculty Publications

Discussions of HBCU students’ content knowledge have centered around developing high impact, asset-based approaches to learning (Williams et al, 2022). So, HBCU teacher preparation providers (TPPs) can also focus efforts on culturally sustaining approaches to developing candidates’ content knowledge and researching how high impact practices, like teaching simulations, can help prepare candidates for classrooms. This exploratory case study uses critical cases (n=2); findings suggest candidates have a developing understanding of content, which forms a solid basis for increasing their knowledge. MRTSs are addressed as a potential high impact, culturally sustaining practice for building candidates’ content knowledge. Further, HBCU TPPs can …


Behind The Screen: Exploring Parental Roles In K-12 Online Education, Barbara T. Sandberg, Charles R. Graham, Jered Borup, Richard E. West, Rocio Quiroga Velasquez Dec 2024

Behind The Screen: Exploring Parental Roles In K-12 Online Education, Barbara T. Sandberg, Charles R. Graham, Jered Borup, Richard E. West, Rocio Quiroga Velasquez

Faculty Publications

Independent engagement can be challenging for K-12 online students. Parents’ physical presence makes them an important source of engagement support. Previous research on parental support in online courses is limited and focused on asynchronous learning within a single program. Since the COVID-19 pandemic, online enrollments have grown and instructional modalities have evolved. To better understand parental support post-Covid, we interviewed 21 parents across eight online programs with asynchronous, synchronous, and bichronous course offerings. Parents identified their affective, behavioral, cognitive, and other support roles. Implications for parental roles in addressing the academic engagement gap are provided to both researchers and practitioners.


Integrated Child Nutrition, Parenting, And Health Intervention In Rural Liberia: A Mixed-Methods Feasibility Study, Sejla Isanovic, Musa Sanoe, Shelbie Wooten, Edward A. Frongillo Ph.D., Aisha K. Yousafzai, Christine E. Blake Ph.D., Rd, Mufaro Kanyangarara Ph.D., Melanie Swan, Nicole Rodger, Miriam Murray, Leila M. Larson Ph.D., Mph Dec 2024

Integrated Child Nutrition, Parenting, And Health Intervention In Rural Liberia: A Mixed-Methods Feasibility Study, Sejla Isanovic, Musa Sanoe, Shelbie Wooten, Edward A. Frongillo Ph.D., Aisha K. Yousafzai, Christine E. Blake Ph.D., Rd, Mufaro Kanyangarara Ph.D., Melanie Swan, Nicole Rodger, Miriam Murray, Leila M. Larson Ph.D., Mph

Faculty Publications

In Liberia, children are exposed to multiple forms of adversity which can negatively impact their health and development. Research is needed to examine the feasibility and benefits of integrated interventions that can be incorporated into existing health delivery programs to simultaneously address low responsive stimulation, undernutrition, and infection. This study assessed the feasibility of an integrated intervention promoting psychosocial stimulation and improved child feeding by the provision of eggs and fish. The integrated intervention was incorporated into an existing government health program. Thirty female caregiver-child dyads were randomly selected from two rural communities in Liberia. Participants received fortnightly group parenting …


Introducing The Second-Order Features Adjoint Sensitivity Analysis Methodology For Neural Ordinary Differential Equations—I: Mathematical Framework, Dan Gabriel Cacuci Dec 2024

Introducing The Second-Order Features Adjoint Sensitivity Analysis Methodology For Neural Ordinary Differential Equations—I: Mathematical Framework, Dan Gabriel Cacuci

Faculty Publications

This work introduces the mathematical framework of the novel “First-Order Features Adjoint Sensitivity Analysis Methodology for Neural Ordinary Differential Equations” (1st-FASAM-NODE). The 1st-FASAM-NODE methodology produces and computes most efficiently the exact expressions of all of the first-order sensitivities of NODE-decoder responses with respect to the parameters underlying the NODE’s decoder, hidden layers, and encoder, after having optimized the NODE-net to represent the physical system under consideration. Building on the 1st-FASAM-NODE, this work subsequently introduces the mathematical framework of the novel “Second-Order Features Adjoint Sensitivity Analysis Methodology for Neural Ordinary Differential Equations (2nd-FASAM-NODE)”. The 2nd-FASAM-NODE methodology efficiently computes the exact expressions …


Investigation Of Magnesium-Potassium Phosphates As Potential Nuclear Waste Form For The Immobilization Of Minor Actinides, Hans Conrad Zur Loye, Petr Vecernik, Monika Kiselova, Vlastislav Kašpar, Hana Korenkova, Vlastimil Miller, Petr Bezdicka, Jan Šubrt, Natalija Murafa, Volodymyr Shkuropatenko, Sergey Sayenko Dec 2024

Investigation Of Magnesium-Potassium Phosphates As Potential Nuclear Waste Form For The Immobilization Of Minor Actinides, Hans Conrad Zur Loye, Petr Vecernik, Monika Kiselova, Vlastislav Kašpar, Hana Korenkova, Vlastimil Miller, Petr Bezdicka, Jan Šubrt, Natalija Murafa, Volodymyr Shkuropatenko, Sergey Sayenko

Faculty Publications

Several recent studies have evaluated technologies of spent nuclear fuel processing specifically for solidifying transuranic (TRU) waste as a by-product of fission. Of the TRU group, plutonium and the minor actinides will be responsible for the bulk of the radiotoxicity and heat generation of spent nuclear fuel in the long term (300 to 20,000 years). In this study, we investigated magnesium potassium phosphate (MKP)-based compounds as host waste forms for the encapsulation of inactive trivalent Nd and Sm as analogues of the minor trivalent actinides, Am and Cm. Waste forms were fabricated under ambient atmospheric conditions by adding 5 wt.% …


Controlling Anti-Asian Conduct On College Campuses: Can Including Ethnic Studies Programs Help?, Hani Morgan Dec 2024

Controlling Anti-Asian Conduct On College Campuses: Can Including Ethnic Studies Programs Help?, Hani Morgan

Faculty Publications

The COVID-19 pandemic has triggered hostile acts against Asian college students. One of the ways to respond to these acts is to increase Asian American ethnic studies programs and courses. Although critics argue that ethnic studies cause divisiveness, research indicates that they are beneficial to students from all groups. University administrators may fear implementing these programs because they sometimes associate them with the violence that occurred during the late 1960s when students demanded ethnic studies to be included in the college curriculum. But this to a great extent by the poor representation of racial minority groups in the curriculum and …


Strategic (Non)Disclosure: Activation And Avoidance Of Social Ties Among Women Seeking Abortion, Kathleen Broussard Dec 2024

Strategic (Non)Disclosure: Activation And Avoidance Of Social Ties Among Women Seeking Abortion, Kathleen Broussard

Faculty Publications

The increased politicization of sexual and reproductive health has created barriers to medically necessary care. In absence of formal health care, social ties become critical sources of information and resources, yet the disclosure of stigmatized health needs carries significant risk. How do people navigate the risks and benefits of disclosure when seeking care for stigmatized needs? Drawing on original survey data (N = 153) and in-depth interviews (N = 55) with women who attempted a self-managed abortion, I first describe the distinct roles of weak and strong ties in women’s health-seeking experiences. I then demonstrate how both partial disclosure and …


Preserving The Future Of Juries And Jury Trials, Paula Hannaford-Agor, Hope Forbush, Miriam Hamilton, Jawwaad Johnson, Morgan Moffett Dec 2024

Preserving The Future Of Juries And Jury Trials, Paula Hannaford-Agor, Hope Forbush, Miriam Hamilton, Jawwaad Johnson, Morgan Moffett

Faculty Publications

To preserve the future of juries and jury trials, the National Center for State Courts (NCSC) convened a meeting of representatives from a broad array of justice system stakeholders as a project under the Justice for All Reauthorization Act (JFARA). To frame the stakeholder discussions, NCSC employed strategic foresight, a methodological approach designed to explore a range of possible futures of juries and jury trials within the American justice system as a vehicle for identifying critical vulnerabilities within the current jury system and proposing targeted strategies to preserve and strengthen jury trials. Critical vulnerabilities are those areas of weakness that …


An Account Of The 1453 Ce Ottoman Siege Of Constantinople Interpreted Through A First Century Bce Jewish Text: How An Ancient Collection Of Second Temple Period Poems Changed The Course Of Western Civilization, Kenneth Atkinson Dec 2024

An Account Of The 1453 Ce Ottoman Siege Of Constantinople Interpreted Through A First Century Bce Jewish Text: How An Ancient Collection Of Second Temple Period Poems Changed The Course Of Western Civilization, Kenneth Atkinson

Faculty Publications

On 29 May 1453 CE, the besieged Christian occupants of Constantinople — the capital of the Byzantine Empire and the last surviving portion of the former Roman Empire — knew the end was near when they heard 50,000-80,000 angry Ottoman soldiers, including 5,000 to 10,000 of the elite Janissaries — the Sultan’s shook troops — preparing to breach its walls after a 53-day siege. The 7,000-man army defending the city knew that all was lost. The 21-year-old Sultan Mehmet II — given the sobriquet “the Conqueror” for capturing the city — leveled the roads so his army could reach Constantinople’s …


Sexual Orientation, Gender Identity And Virologic Failure Among People With Hiv: A Cohort Study In All Of Us Research Program, Fanghui Shi, Ruilie Cai, Buwei He, Xiaoming Li Ph.D., Xueying Yang Ph.D., Sharon Weissman, Bankole Olatosi Ph.D., Jiajia Zhang Ph.D. Dec 2024

Sexual Orientation, Gender Identity And Virologic Failure Among People With Hiv: A Cohort Study In All Of Us Research Program, Fanghui Shi, Ruilie Cai, Buwei He, Xiaoming Li Ph.D., Xueying Yang Ph.D., Sharon Weissman, Bankole Olatosi Ph.D., Jiajia Zhang Ph.D.

Faculty Publications

Background: Sexual and gender minorities (SGMs) are at higher risk of HIV incidence compared to their heterosexual cisgender counterparts. Despite the high HIV disease burden among SGMs, there was limited data on whether they are at higher risk of virologic failure, which may lead to potential disease progression and increased transmission risk. The All of Us (AoU) Research Program, a national community-engaged program aiming to improve health and facilitate health equity in the United States by partnering with one million participants, provides a promising resource for identifying a diverse and large volunteer TGD cohort. Leveraging various data sources available through …


The Dynamic Risk Factors Of Cardiovascular Disease Among People Living With Hiv: A Real-World Data Study, Ziang Liu, Jiajia Zhang Ph.D., Xueying Yang Ph.D., Haoyuan Gao, Shujie Chen, Sharon Weissman, Bankole Olatosi Ph.D., Xiaoming Li Ph.D. Dec 2024

The Dynamic Risk Factors Of Cardiovascular Disease Among People Living With Hiv: A Real-World Data Study, Ziang Liu, Jiajia Zhang Ph.D., Xueying Yang Ph.D., Haoyuan Gao, Shujie Chen, Sharon Weissman, Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Background: This study aims to investigate the incidence and dynamic risk factors for cardiovascular diseases (CVD) among people living with HIV (PLWH).

Methods: In this population-based statewide cohort study, we utilized integrated electronic health records data to identify adult (age ≥ 18) who were diagnosed with HIV between 2006 and 2019 and were CVD event-free at the HIV diagnosis in South Carolina. The associations of HIV-related factors and traditional risk factors with the CVD incidence were investigated during the overall study period, and by different follow-up periods (i.e., 0-5yrs, 6-10yrs 11-15yrs) using multivariable logistic regression models.

Results: Among 9,082 eligible …


Redressing Judicial Misbehavior: An Integrated Approach To Judicial Immunity, Nancy Amoury Combs Dec 2024

Redressing Judicial Misbehavior: An Integrated Approach To Judicial Immunity, Nancy Amoury Combs

Faculty Publications

Immunities generate intense public interest and controversy. Whether it is the sweeping presidential immunity that former President Trump has claimed or the qualified immunity that rogue police invoke to evade financial responsibility for their brutality, immunities stand as a highly contested aspect of the American legal system. Judicial immunity incites similar controversy. American judges possess absolute immunity from civil suits for their judicial acts, so victims are barred from seeking civil compensation, even against judges who engage in purposeful or malicious misconduct from the bench. For decades scholars have sought to curtail absolute judicial immunity, but they have overlooked a …


Law And Equity On Appeal, Aaron-Andrew P. Bruhl Dec 2024

Law And Equity On Appeal, Aaron-Andrew P. Bruhl

Faculty Publications

Most lawyers know that the Federal Rules of Civil Procedure merged the divergent trial procedures of the common law and of equity, but fewer are familiar with the development of federal appellate procedure. Here too there is a story of the merger of two distinct systems. At common law, a reviewing court examined the record for errors of law after the final trial judgment. In the equity tradition, an appeal was a rehearing of the law and the facts that aimed at achieving justice and did not need to await a final judgment. Unlike the story of federal trial procedure, …


Introducing The Second-Order Features Adjoint Sensitivity Analysis Methodology For Neural Ordinary Differential Equations—Ii: Illustrative Application To Heat And Energy Transfer In The Nordheim–Fuchs Phenomenological Model For Reactor Safety, Dan Gabriel Cacuci Dec 2024

Introducing The Second-Order Features Adjoint Sensitivity Analysis Methodology For Neural Ordinary Differential Equations—Ii: Illustrative Application To Heat And Energy Transfer In The Nordheim–Fuchs Phenomenological Model For Reactor Safety, Dan Gabriel Cacuci

Faculty Publications

This work presents an illustrative application of the newly developed “Second-Order Features Adjoint Sensitivity Analysis Methodology for Neural Ordinary Differential Equations (2nd-FASAM-NODE)” methodology to determine most efficiently the exact expressions of the first- and second-order sensitivities of NODE decoder responses to the neural net’s underlying parameters (weights and initial conditions). The application of the 2nd-FASAM-NODE methodology will be illustrated using the Nordheim–Fuchs phenomenological model for reactor safety, which describes a short-time self-limiting power transient in a nuclear reactor system having a negative temperature coefficient in which a large amount of reactivity is suddenly inserted. The representative model responses that will …


Human Capital Assessment In Indigenous Regions To Enable Sustainable Futures, Victoria N. Sharakhmatova, Elena G. Mikhailova Nov 2024

Human Capital Assessment In Indigenous Regions To Enable Sustainable Futures, Victoria N. Sharakhmatova, Elena G. Mikhailova

Faculty Publications

This study is dedicated to the economic valuation of human capital (HC) in the regions where the Indigenous peoples of Kamchatka reside. The entire Kamchatksky Krai is considered an Indigenous people’s ancestral territory. However, in this study, only municipalities whose population is more than one-third Indigenous were chosen for the assessment. This includes six municipal districts and one urban district (Aleytsky, Bystrinsky, Karaginsky, Olyutorsky, Penzhinsky, and Tigilsky municipal districts and Palana urban district). The study employs statistical analysis and integrated, situational approaches: the investment approach was deemed the most appropriate tool for the economic assessment of HC in Indigenous territories. …


Spatial Pattern And Differential Expression Analysis With Spatial Transcriptomic Data, Fei Qin, Xizhi Luo, Bo Cai Ph.D., Feifei Xiao, Guoshuai Cai Nov 2024

Spatial Pattern And Differential Expression Analysis With Spatial Transcriptomic Data, Fei Qin, Xizhi Luo, Bo Cai Ph.D., Feifei Xiao, Guoshuai Cai

Faculty Publications

The emergence of spatial transcriptomic technologies has opened new avenues for investigating gene activities while preserving the spatial context of tissues. Utilizing data generated by such technologies, the identification of spatially variable (SV) genes is an essential step in exploring tissue landscapes and biological processes. Particularly in typical experimental designs, such as case-control or longitudinal studies, identifying SV genes between groups is crucial for discovering significant biomarkers or developing targeted therapies for diseases. However, current methods available for analyzing spatial transcriptomic data are still in their infancy, and none of the existing methods are capable of identifying SV genes between …


Impact Of Vaporization On Drop Aerobreakup, B. Boyd, S. Becker, Yue Stanley Ling Nov 2024

Impact Of Vaporization On Drop Aerobreakup, B. Boyd, S. Becker, Yue Stanley Ling

Faculty Publications

Aerodynamic breakup of vaporizing drops is commonly seen in many spray applications. While it is well known that vaporization can modulate interfacial instabilities, the impact of vaporization on drop aerobreakup is poorly understood. Detailed interface-resolved simulations were performed to systematically study the effect of vaporization, characterized by the Stefan number, on the drop breakup and acceleration for different Weber numbers and density ratios. It is observed that the resulting asymmetric vaporization rates and strengths of Stefan flow on the windward and leeward sides of the drop hinder bag development and prevent drop breakup. The critical Weber number thus generally increases …


Bound States And Particle Production By Breather-Type Background Field Configurations, Abhishek Rout, Brett Altschul Nov 2024

Bound States And Particle Production By Breather-Type Background Field Configurations, Abhishek Rout, Brett Altschul

Faculty Publications

We investigate the interaction of fermion fields with oscillating domain walls, inspired by breather-type solutions of the sine-Gordon equation, a nonlinear system of fundamental importance. Our study focuses on the fermionic bound states and particle production induced by a time-dependent scalar background field. The fermions couple to two domain walls undergoing harmonic motion, and we explore the resulting dynamics of the fermionic wave functions. We demonstrate that while fermions initially form bound states around the domain walls, the energy provided by the oscillatory motion of the scalar field induces an outward flux of fermions and antifermions, leading to particle production …


Effective Support Strategies Serving Diverse Teacher Candidates In Paraprofessional Teacher Education Programs, Angela Christine Griner, Debra K. Wellman Nov 2024

Effective Support Strategies Serving Diverse Teacher Candidates In Paraprofessional Teacher Education Programs, Angela Christine Griner, Debra K. Wellman

Faculty Publications

Paraprofessionals remain a rich resource for our children and our school communities. Teacher education programs that have sought to provide pathways to teaching certification for paraprofessionals recognize this. Over the last 25 years, research has shown well-documented models for programs and strategies that support candidates in these programs, as well as the obstacles and challenges those programs and participants face. This article presents a descriptive case study of the first three years of a para-to-teacher program, across three cohorts of participants at a small liberal arts institution. Implications for best practices tied to collaborative leadership, relational approaches, and collaborative program …


Motivational Dysregulation With Melanocortin 4 Receptor Haploinsufficiency, Alex M. Steiner, Robert F. Roscoe, Rosemarie M. Booze, Charles F. Mactutus Nov 2024

Motivational Dysregulation With Melanocortin 4 Receptor Haploinsufficiency, Alex M. Steiner, Robert F. Roscoe, Rosemarie M. Booze, Charles F. Mactutus

Faculty Publications

Obesity, by any standard, is a global health crisis. Both genetic and dietary contributions to the development and maintenance of obesity were integral factors of our experimental design. As mutations of the melanocortin 4 receptors (MC4R) are the leading monogenetic cause of obesity, MC4R haploinsufficient rats were fed a range of dietary fat (0–12 %) in a longitudinal design. Physiological and motivational assessments were performed using a locomotor task, a 5-choice sucrose preference task, an operant task with fixed and progressive ratios, as well as a distraction operant task. Dendritic spine morphology of medium spiny neurons (MSNs) of the nucleus …


Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude Nov 2024

Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude

Faculty Publications

Triple-negative breast cancers (TNBC) are treated primarily by chemotherapy and lack clinically validated therapeutic targets. In particular, inhibitors of the PI3K/AKT/mTOR pathway, abnormally activated in many breast cancers, failed to achieve clinical efficacy in TNBC due to the development of adaptive drug resistance, which is largely driven by the transcriptomic plasticity of TNBC. Expression of CDK8/19 Mediator kinases that control transcriptional reprogramming correlates with relapse-free survival and treatment failure in breast cancer patients, including TNBC. We now investigated how CDK8/19 inhibitors affect the growth of TNBC tumors and their response to mTOR and AKT inhibitors. In contrast to the effects …


Sound Innovations For Biofabrication And Tissue Engineering, Mengxi Wu, Zhiteng Ma, Zhenhua Tian, Joseph Rich, Xin He, Jianping Xia, Ye He, Kaichun Yang, Shujie Yang, Kam W. Leong, Luke P. Lee, Tony Jun Huang Nov 2024

Sound Innovations For Biofabrication And Tissue Engineering, Mengxi Wu, Zhiteng Ma, Zhenhua Tian, Joseph Rich, Xin He, Jianping Xia, Ye He, Kaichun Yang, Shujie Yang, Kam W. Leong, Luke P. Lee, Tony Jun Huang

Faculty Publications

Advanced biofabrication techniques can create tissue-like constructs that can be applied for reconstructive surgery or as in vitro three-dimensional (3D) models for disease modeling and drug screening. While various biofabrication techniques have recently been widely reviewed in the literature, acoustics-based technologies still need to be explored. The rapidly increasing number of publications in the past two decades exploring the application of acoustic technologies highlights the tremendous potential of these technologies. In this review, we contend that acoustics-based methods can address many limitations inherent in other biofabrication techniques due to their unique advantages: noncontact manipulation, biocompatibility, deep tissue penetrability, versatility, precision …


Rural-Urban Disparities And Trends In Cancer Screening: An Analysis Of Behavioral Risk Factor Surveillance System Data (2018-2022), Gabriel A. Benavidez, Ami E. Sedani, Tisha Moniek Felder Phd, Msw, Matthew Asare, Charles R. Rogers Nov 2024

Rural-Urban Disparities And Trends In Cancer Screening: An Analysis Of Behavioral Risk Factor Surveillance System Data (2018-2022), Gabriel A. Benavidez, Ami E. Sedani, Tisha Moniek Felder Phd, Msw, Matthew Asare, Charles R. Rogers

Faculty Publications

Background

Despite evidence of the benefit of routine cancer screenings, data show a concerning decline in cancer screening uptake for multiple cancers. This analysis aimed to examine rural-urban differences in recent trends for being up-to-date with screenings for breast, cervical, and colorectal cancers.

Methods

We used 2018, 2020, and 2022 Behavioral Risk Factor Surveillance System data to assess up-to-date cancer screening status among eligible adults in the United States. We calculated weighted prevalence estimates overall and stratified by county-level rural-urban classification. We used survey-weighted multivariable logistic regression models to examine rural-urban disparities in cancer screening up-to-date status by year.

Results …


State Divorce Laws, Reproductive Care Policies, And Pregnancy-Associated Homicide Rates, 2018-2021, Kaitlin M. Boyle, Wendy Regoeczi, Chase B. Meyer Nov 2024

State Divorce Laws, Reproductive Care Policies, And Pregnancy-Associated Homicide Rates, 2018-2021, Kaitlin M. Boyle, Wendy Regoeczi, Chase B. Meyer

Faculty Publications

Importance: Barriers to divorce and reproductive health care can threaten the health and safety of pregnant and recently pregnant females.

Objective: To examine state laws about divorce, reproductive health care (access to contraception, family planning services, and abortion), and pregnancy-associated homicide rates in US states over a 4-year period (2018-2021).

Design, Setting, and Participants: In this cross-sectional study, bivariate tests and regressions were used to analyze crude rates of pregnancy-associated homicide from the National Violent Death Reporting System in 181 state-years for calendar years 2018 to 2021, with analyses conducted on September 8, 2024.

Exposures: Access to divorce while pregnant …


Imagination Grows A Better World: Courage, Creativity, And Fantastic Futures, Janet Croft Nov 2024

Imagination Grows A Better World: Courage, Creativity, And Fantastic Futures, Janet Croft

Faculty Publications

Our field is requiring ever more courage from us as we face challenges to our bedrock beliefs in free access to information and the value of diverse viewpoints, of representation of different ways of being and living, of higher education, and of imagination itself. Where can we find inspiration to keep going? In order to meet the challenges we face with creativity and courage, we need both the ability to imagine a better world and the determination to work to bring this world into being. I’ll talk about some inspirational examples of the pairing of courage and creativity in my …


Single-Molecule Profiling Of Per- And Polyfluoroalkyl Substances By Cyclodextrin Mediated Host-Guest Interactions Within A Biological Nanopore, Xiaojun Wei, Aditya Choudhary, Leon Y. Wang, Lixing Yang, Mark J. Uline, Mario Tagliazucchi, Qian Wang, Dmitry Bedrov, Chang Liu Nov 2024

Single-Molecule Profiling Of Per- And Polyfluoroalkyl Substances By Cyclodextrin Mediated Host-Guest Interactions Within A Biological Nanopore, Xiaojun Wei, Aditya Choudhary, Leon Y. Wang, Lixing Yang, Mark J. Uline, Mario Tagliazucchi, Qian Wang, Dmitry Bedrov, Chang Liu

Faculty Publications

Biological nanopores are increasingly used in molecular sensing due to their single-molecule sensitivity. The detection of per- and polyfluoroalkyl substances (PFAS) like perfluorooctanoic acid and perfluorooctane sulfonic acid is critical due to their environmental prevalence and toxicity. Here, we investigate selective interactions between PFAS and four cyclodextrin (CD) variants (α-, β-, γ-, and 2-hydroxypropyl-γ-CD) within an α-hemolysin nanopore. We demonstrate that PFAS molecules can be electrochemically sensed by interacting with a γ-CD in a nanopore. Using HP-γ-CDs with increased steric resistance, we can identify homologs of the perfluoroalkyl carboxylic acid and the perfluoroalkyl sulfonic acid families and detect common PFAS …


Ignis: A One-Dimensional Laminar Flame Code, Jansen P. Berryhill, Jacob K. Spinti, David O. Lignell Nov 2024

Ignis: A One-Dimensional Laminar Flame Code, Jansen P. Berryhill, Jacob K. Spinti, David O. Lignell

Faculty Publications

Laminar flame codes have an important role in combustion modeling. They can provide a fundamental understanding of flame dynamics and provide a basis for building subgrid scale models in turbulent flow simulations. This paper presents Ignis, an open-source laminar flame code with the capability to offload submodels, like soot formation and radiation, using external packages and libraries. Ignis is written in C++, is documented with Doxygen, and is available on GitHub. It contains three different flame formulations: diffusion flames, premixed flames, and laminar flamelets solved in the mixture fraction coordinate. An option to facilitate creation of a diffusion flame table …


Sculpting Success: The Importance Of Diet And Physical Activity To Support Skeletal Muscle Health During Weight Loss With New Generation Anti-Obesity Medications, Gregory J. Grosicki, Nikhil V. Dhurandhar, Jessica L. Unick, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, J. Graham Thomas, Holly Lofton, Madelyn C. Shepherd, Jessica Kiel, Christopher Coleman, Satya S. Jonnalagadda Nov 2024

Sculpting Success: The Importance Of Diet And Physical Activity To Support Skeletal Muscle Health During Weight Loss With New Generation Anti-Obesity Medications, Gregory J. Grosicki, Nikhil V. Dhurandhar, Jessica L. Unick, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, J. Graham Thomas, Holly Lofton, Madelyn C. Shepherd, Jessica Kiel, Christopher Coleman, Satya S. Jonnalagadda

Faculty Publications

Obesity is a public health crisis, with prevalence rates tripling over the past 60 y. Although lifestyle modifications, such as diet and physical activity, remain the first-line treatments, recent anti-obesity medications (AOMs) have been shown to achieve greater reductions in body weight and fat mass. However, AOMs also reduce fat-free mass, including skeletal muscle, which has been demonstrated to account for 20% to 50% of total weight loss. This can equate to ∼6 kg or 10% of total lean mass after 12–18 mo, a loss comparable to a decade of human aging. Despite questions surrounding the clinical relevance of weight …


Bostock And The Forgotten Eeoc, Sandra F. Sperino Nov 2024

Bostock And The Forgotten Eeoc, Sandra F. Sperino

Faculty Publications

In Bostock v. Clayton County, Georgia, the Supreme Court formally recognized that federal discrimination law prohibits discrimination based on sexual orientation and gender identity. The opinion barely mentioned the Equal Employment Opportunity Commission (EEOC), the federal agency charged with enforcing federal discrimination law. Reading Bostock, it would be easy to get the impression that the EEOC played little to no role in the outcome. This Essay reclaims and restores the EEOC's role.

In restoring the EEOC's role in this story, two themes emerge. First, Bostock's methodology erases the administrative agency tasked with enforcing Title VII in ways that are inconsistent …


Online Eye Tracking For Aphasia: A Feasibility Study Comparing Web And Lab Tracking And Implications For Clinical Use, Willem S. Van Boxtel, Michael Linge, Rylee Manning, Lily N. Haven, Jiyeon Lee Nov 2024

Online Eye Tracking For Aphasia: A Feasibility Study Comparing Web And Lab Tracking And Implications For Clinical Use, Willem S. Van Boxtel, Michael Linge, Rylee Manning, Lily N. Haven, Jiyeon Lee

Faculty Publications

Background & Aims: Studies using eye-tracking methodology have made important contributions to the study of language disorders such as aphasia. Nevertheless, in clinical groups especially, eye-tracking studies often include small sample sizes, limiting the generalizability of reported findings. Online, webcam-based tracking offers a potential solution to this issue, but web-based tracking has not been compared with in-lab tracking in past studies and has never been attempted in groups with language impairments. Materials & Methods: Patients with post-stroke aphasia (n = 16) and age-matched controls (n = 16) completed identical sentence-picture matching tasks in the lab (using an EyeLink system) and …