Digital Commons Network^™

Closed-Form Solution For Shock Wave Propagation In Density-Graded Cellular Material Under Impact, Vjendra Gupta, Addis Kidane, Michael A. Sutton

Faculty Publications

Density-graded cellular materials have tremendous potential in structural applications where impact resistance is required. Cellular materials subjected to high impact loading result in a compaction type deformation, usually modeled using continuum-based shock theory. The resulting governing differential equation of the shock model is nonlinear, and the density gradient further complicates the problem. Earlier studies have employed numerical methods to obtain the solution. In this study, an analytical closed-form solution is proposed to predict the response of density-graded cellular materials subjected to a rigid body impact. Solutions for the velocity of the impinging rigid body mass, energy absorption capacity of the …

Rabies Postexposure Prophylaxis In The United States: Opportunities To Improve Access, Coordination, And Delivery, Gavin T. Howington, Huy-Binh Nguyen, P Brandon Bookstaver, Peter Akpunonu, Joshua T. Swan

Faculty Publications

No abstract provided.

Strategic Human Resource Management And Covid-19: Emerging Challenges And Research Opportunities, David G. Collings, John Mcmackin, Anthony Nyberg, Patrick M. Wright

Faculty Publications

No abstract provided.

Evaluation Of Circulating Levels Of Interleukin-10 And Interleukin-16 And Dietary Inflammatory Index In Lebanese Knee Osteoarthritis Patients, Zeina El-Ali, Germine El-Kassas, Fouad M. Ziade, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Nisrine Bissar

Faculty Publications

Objectives

To investigate plasma concentrations of Interleukin-16 (IL-16) and Interleukin-10 (IL-10) in Lebanese knee osteoarthritis (KOA) patients and to examine the association between the diet-associated inflammation and increased risk for KOA.

Methods

A total of 208 study participants were assigned to one of the 3 groups: Diagnosed Knee Osteoarthritis group (DKOA) (N = 78); Undiagnosed Knee Osteoarthritis group (UKOA) (N = 60) and controls matched on age, sex and sociodemographic characteristics (N = 70). UKOA represents KOA features before they are altered by therapeutic intervention and lifestyle modifications that follow the diagnosis. Energy-adjusted dietary inflammatory index (E-DII™) scores were calculated …

Comparing Dietary Score Associations With Lipoprotein Particle Subclass Profiles: A Cross-Sectional Analysis Of A Middle-To Older-Aged Population, Seán R. Millar, Pilar Navarro, Janas M. Harrington, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ivan J. Perry, Catherine M. Phillips

Faculty Publications

Background and objectives: Lipoprotein particle concentrations and size are associated with increased risk for atherosclerosis and premature cardiovascular disease. Studies also suggest that certain dietary behaviours may be cardioprotective. Limited comparative data regarding any dietary score/index-lipoprotein particle subclass associations exist. Thus, our objective was to assess relationships between the Dietary Approaches to Stop Hypertension (DASH), Health Eating Index-2015 (HEI-2015), Mediterranean Diet (MD) and Energy-adjusted Dietary Inflammatory Index (E-DII™) scores and plasma lipids and lipoprotein profiles to test the hypothesis that healthier diet (better quality and more anti-inflammatory) would be associated with a more favourable lipoprotein profile.

Materials and methods: This …

Investigating Developmental Changes In Scalp-To-Cortex Correspondence Using Diffuse Optical Tomography Sensitivity In Infancy, Xiaoxue Fu, John E. Richards

Faculty Publications

Significance: Diffuse optical tomography (DOT) uses near-infrared light spectroscopy (NIRS) to measure changes in cerebral hemoglobin concentration. Anatomical interpretations of NIRS data require accurate descriptions of the cranio-cerebral relations and DOT sensitivity to the underlying cortical structures. Such information is limited for pediatric populations because they undergo rapid head and brain development.

Aim: We aim to investigate age-related differences in scalp-to-cortex distance and mapping between scalp locations and cortical regions of interest (ROIs) among infants (2 weeks to 24 months with narrow age bins), children (4 and 12 years), and adults (20 to 24 years).

Approach: We …

Perspective: The Importance Of Water Security For Ensuring Food Security, Good Nutrition, And Well-Being, Sera L. Young, Edward A. Frongillo Jr., Zeina Jamaluddine, Hugo Melgar-Quiñonez, Rafael Pérez-Escamilla, Claudia Ringler, Asher Y. Rosinger

Faculty Publications

Water security is a powerful concept that is still in its early days in the field of nutrition. Given the prevalence and severity of water issues and the many interconnections between water and nutrition, we argue that water security deserves attention commensurate with its importance to human nutrition and health. To this end, we first give a brief introduction to water insecurity and discuss its conceptualization in terms of availability, access, use, and stability. We then lay out the empirical grounding for its assessment. Parallels to the food-security literature are drawn throughout, both because the concepts are analogous and food …

Physical Activity Among Adults Residing In 11 Countries During The Covid-19 Pandemic Lockdown, Kele Ding, Jingzhen Yang, Ming-Kai Chin, Lindsay Sullivan, J. Larry Durstine, Verónica Violant-Holz, Giyasettin Demirhan, Nara R.C. Oliveira, Biljana Popeska, Garry Kuan, Waheeda Khan, Jianhui Dai, Xia Xu, Zornitza Mladenova, Govindasamy Balasekaran, Gary A. Smith, Global Community Health-Covid-19 Collaborative Research Team

Faculty Publications

During the novel coronavirus (COVID-19) pandemic, physical activity (PA) behaviors were altered worldwide due to public health measures such as “lockdown.” This study described PA among adults residing in 11 countries during COVID-19 lockdown and examined factors associated with PA engagement. We conducted a cross-sectional anonymous survey among adults (≥18 years old) in 11 countries (Brazil, Bulgaria, China, India, Ireland, Malaysia, North Macedonia, Singapore, Spain, Turkey, United States). Of 11,775 participants, 63.7% were female and 52.8% were 18–34 years old. More than 40% of participants were insufficiently active (43.9%) and reported a decrease in their PA during lockdown (44.8%). Statistically …

Influencing Perceptions Of Stem Through The Best Stem Books List, Scott Bartholomew, Alexia Seymour

Faculty Publications

One day, while discussing engineering and science as potential career options with a female student, we opened a search engine and typed in “engineer” and “scientist.” However, on the first pages of image results, only one female appeared for engineering and only a few females appeared for “scientist” (see Figure 1). This disparity was disturbing—if this student never saw another person like her filling careers in STEM fields, would she ever “picture herself” in those fields?

Free Three-Dimensional Carborane Carbanions, H.D.A. Zzzchathumal Jayaweera, Md. Mamdudur Rahman, Perry J. Pellechia, Mark D. Smith, Dmitry V. Peryshkov

Faculty Publications

Carbon atom functionalization via generation of carbanions is the cornerstone of carborane chemistry. In this work, we report the synthesis and structural characterization of free ortho-carboranyl [C₂B₁₀H₁₁]⁻, a three-dimensional inorganic analog of the elusive phenyl anion that features a “naked” carbanion center. The first example of a stable, discrete C(H)-deprotonated carborane anion was isolated as a completely separated ion pair with a crown ether-encapsulated potassium cation. An analogous approach led to the isolation and structural characterization of a doubly deprotonated 1,1′-bis(o-carborane) anion [C₂B₁₀H₁₀] …

On Using The Bmcsl Equation Of State To Renormalize The Onsager Theory Approach To Modeling Hard Prolate Spheroidal Liquid Crystal Mixtures, Donya Ohadi, David S. Corti, Mark J. Uline

Faculty Publications

Modifications to the traditional Onsager theory for modeling isotropic–nematic phase transitions in hard prolate spheroidal systems are presented. Pure component systems are used to identify the need to update the Lee–Parsons resummation term. The Lee–Parsons resummation term uses the Carnahan–Starling equation of state to approximate higher-order virial coefficients beyond the second virial coefficient employed in Onsager’s original theoretical approach. As more exact ways of calculating the excluded volume of two hard prolate spheroids of a given orientation are used, the division of the excluded volume by eight, which is an empirical correction used in the original Lee–Parsons resummation term, must …

A Qualitative Study Of Stress And Coping To Inform The Leads Health Promotion Trial For African American Adolescents With Overweight And Obesity, Mary Quattlebaum, Colby Kipp, Dawn Wilson-King, Allison Sweeney Ph.D.

Faculty Publications

The purpose of this study was to conduct in-depth individual interviews with 30 African American adolescents with overweight and obesity and their families (caregiver/adolescent dyads) to gain a better understanding of how to integrate stress and coping essential elements into an existing family-based health promotion program for weight loss. Interview data from 30 African American adolescents with overweight and obesity (Mage = 15.30 ± 2.18; MBMI%-ile = 96.7 ± 3.90) were transcribed and coded for themes using inductive and deductive approaches by two independent coders. Inter-rater reliability was acceptable (r = 0.70–0.80) and discrepancies were resolved to 100% agreement. The …

An Evidence-Based Review Of The Pathophysiology, Treatment, And Prevention Of Exercise-Associated Muscle Cramps, Kevin C. Miller, Brendon P. Mcdermott, Susan W. Yeargin, Aidan Fiol, Martin P. Schwellnus

Faculty Publications

Exercise-associated muscle cramps (EAMCs) are common and frustrating for athletes and the physically active. We critically appraised the EAMC literature to provide evidence based treatment and prevention recommendations. Although the pathophysiology of EAMCs appears controversial, recent evidence suggests that EAMCs are due to a confluence of unique intrinsic and extrinsic factors rather than a singular cause. The treatment of acute EAMCs continues to include self-applied or clinician-guided gentle static stretching until symptoms abate. Once the painful EAMCs are alleviated, the clinician can continue treatment on the sidelines by focusing on patient-specific risk factors that may have contributed to the onset …

Risk Of Early-Onset Dementia Among Persons With Tinnitus: A Retrospective Case–Control Study, Yen-Fu Cheng, Sudha Xirasagar Mbbs. Ph.D., Tzong- Han Yang, Chuan-Song Wu, Yi-Wei Kao, Herng-Ching Lin

Faculty Publications

Higher rates of poor cognitive performance are known to prevail among persons with tinnitus in all age groups. However, no study has explored the association between tinnitus and early-onset dementia. We hypothesize that tinnitus may precede or occur concurrently with subclinical or early onset dementia in adults younger than 65 years of age. This case–control study used data from the Taiwan National Health Insurance Research Database, identifying 1308 patients with early-onset dementia (dementia diagnosed before 65 years of age) and 1308 matched controls. We used multivariable logistic regressions to estimate odds ratios (ORs) for prior tinnitus among patients with dementia …

Concentrations, Ratios, And Sinking Fluxes Of Major Bioelements At Ocean Station Papa, Montserrat Roca-Martí

Faculty Publications

Fluxes of major bioelements associated with sinking particles were quantified in late summer 2018 as part of the EXport Processes in the Ocean from RemoTe Sensing (EXPORTS) field campaign near Ocean Station Papa in the subarctic northeast Pacific. The thorium-234 method was used in conjunction with size-fractionated (1–5, 5–51, and >51 μm) concentrations of particulate nitrogen (PN), total particulate phosphorus (TPP), biogenic silica (bSi), and particulate inorganic carbon (PIC) collected using large volume filtration via in situ pumps. We build upon recent work quantifying POC fluxes during EXPORTS. Similar remineralization length scales were observed for both POC and PN across …

Clinical Correlations Of Polycomb Repressive Complex 2 In Different Tumor Types, Maksim Erokhin, Olga Chetverina, Balázs Győrffy, Victor V. Tatarskiy, Vladic Mogila, Alexander A. Shtil, Igor Roninson, Jerome Moreaux, Pavel Georgiev, Giacomo Cavalli, Darya Chetverina

Faculty Publications

PRC2 (Polycomb repressive complex 2) is an evolutionarily conserved protein complex required to maintain transcriptional repression. The core PRC2 complex includes EZH2, SUZ12, and EED proteins and methylates histone H3K27. PRC2 is known to contribute to carcinogenesis and several small molecule inhibitors targeting PRC2 have been developed. The present study aimed to identify the cancer types in which PRC2 targeting drugs could be beneficial. We queried genomic and transcriptomic (cBioPortal, KMplot) database portals of clinical tumor samples to evaluate clinical correlations of PRC2 subunit genes. EZH2, SUZ12, and EED gene amplification was most frequently found in prostate cancer, whereas lymphoid …

Review Of The Analysis Of 234Th In Small Volume (2–4 L) Seawater Samples: Improvements And Recommendations, Samantha J. Clevenger, Claudia Benitez-Nelson, Jessica Drysdale, Steven Pike, Viena Puigcorbé, Ken O. Buesseler

Faculty Publications

Schools may be one important context where adolescents learn and shape the behaviors necessary for promoting global inclusivity in adulthood. Given the importance of bystanders in halting bullying and peer aggression, the focus of this study is on both moral judgments regarding one type of bullying, social exclusion, and factors that are associated with bystander intervention. The study includes 896 adolescents, who were 6th (N = 450, M_age = 11.73), and 9th (N = 446, M_age = 14.82) graders, approximately evenly divided by gender. Participants were primarily European–American (63.3%). Results revealed that girls and participants who …

Resistance Exercise, Alone And In Combination With Aerobic Exercise, And Obesity In Dallas, Texas, Us: A Prospective Cohort Study, Angelique G. Brellenthin, Duck-Chul Lee, Jason A. Bennie, Xuemei (Mei) Sui M.D., M.P.H., Ph.D., Steven N. Blair

Faculty Publications

Background

Obesity is a significant and growing public health problem in high-income countries. Little is known about the relationship between resistance exercise (RE), alone and in combination with aerobic exercise (AE), and the risk of developing obesity. The purpose of this prospective cohort study was to examine the associations between different amounts and frequencies of RE, independent of AE, and incident obesity.

Methods and findings

Participants were 11,938 healthy adults ages 18–89 years with a BMI < 30 kg/m2 at baseline who completed at least 2 clinical examinations during 1987–2005 as part of the Aerobics Center Longitudinal Study. Self-reported RE participation in minutes/week and days/week was collected from a standardized questionnaire. Incident obesity was defined as a BMI ≥ 30 kg/m2 at follow-up. Incident obesity was also defined by waist circumference (WC) > 102/88 cm for men/women and percent body fat (PBF) ≥ 25%/30% for men/women at follow-up in participants who were not obese by WC (n …

An Exhaustive Survey On P4 Programmable Data Plane Switches: Taxonomy, Applications, Challenges, And Future Trends, Elie Kfoury, Jorge Crichigno, Elias Bou-Harb

Faculty Publications

High-throughput proteomic profiling using antibody or aptamer-based affinity reagents is used increasingly in human studies. However, direct analyses to address the relative strengths and weaknesses of these platforms are lacking. We assessed findings from the SomaScan1.3K (N = 1301 reagents), the SomaScan5K platform (N= 4979 reagents), and the Olink Explore (N = 1472 reagents) profiling techniques in 568 adults from the Jackson Heart Study and 219 participants in the HERITAGE Family Study across four performance domains: precision, accuracy, analytic breadth, and phenotypic associations leveraging detailed clinical phenotyping and genetic data. Across these studies, we show evidence supporting more reliable protein …

Peer-To-Peer Health Promotion Interventions Among African American Men: A Scoping Review Protocol, Guillermo M. Wippold, Sarah Grace Frary, Demetrius Abshire Phd, Rn, Dawn Wilson-King

Faculty Publications

Background

Health promotion efforts among African American men have been met with significant challenges and have produced limited results. Interventions that do not align with the values, perspectives, and preferences of African American men often produce less effective results. Research among African American men has provided compelling evidence that these men prefer informal networks of health support. Recent successful health promotion efforts among these men have benefited from peer-to-peer models of implementation. To date, no known scoping or systematic review of peer-to-peer health promotion interventions among African American men has been conducted. The goal of this scoping review is to …

The Mexico Simsmoke Tobacco Control Policy Model: Development Of A Simulation Model Of Daily And Nondaily Cigarette Smoking, Luz Maria Sanchez-Romero, Luis Zavala-Arciniega, Luz Myriam Reynales-Shigematsu, Belén Sáenz De Miera-Juárez, Zhe Yuan, Yameng Li, Yan Kwan Lau, Nancy L. Fleischer, Rafael Meza, Jim F. Thrasher Ph.D., Ma, Ms, David T. Levy

Faculty Publications

Background

Nondaily smoking has been on the rise, especially in Mexico. While Mexico has strengthened its tobacco control policies, their effects on nondaily smokers have gone largely unexamined. We developed a simulation model to estimate the impact of tobacco control policies on daily and nondaily smoking in Mexico.

Methods

A previously validated Mexico SimSmoke model that estimated overall trends in smoking prevalence from 2002 through 2013 was extended to 2018 and adapted to distinguish daily and nondaily smoking prevalence. The model was then validated using data from Mexican surveys through 2016. To gauge the potential effects of policies, we compared …

Crack-Length Estimation For Structural Health Monitoring Using The High-Frequency Resonances Excited By The Energy Release During Fatigue-Crack Growth, Joseph Roshan, Hanfei Mei, Asaad Migot, Victor Giurgiutiu

Faculty Publications

Acoustic waves are widely used in structural health monitoring (SHM) for detecting fatigue cracking. The strain energy released when a fatigue crack advances has the effect of exciting acoustic waves, which travel through the structures and are picked up by the sensors. Piezoelectric wafer active sensors (PWAS) can effectively sense acoustic waves due to fatigue-crack growth. Conventional acoustic-wave passive SHM, which relies on counting the number of acoustic events, cannot precisely estimate the crack length. In the present research, a novel method for estimating the crack length was proposed based on the high-frequency resonances excited in the crack by the …

Spatial, Temporal, And Demographic Patterns In Prevalence Of Smoking Tobacco Use And Attributable Disease Burden In 204 Countries And Territories, 1990-2019: A Systematic Analysis From The Global Burden Of Disease Study 2019, Ismaeel Yunusa Ph. D., Marissa B. Reitsma, Parkes J. Kendrick, Emad Ababneh, Cristiana Abbafati, Mohsen Abbasi-Kangevari, Et. Al.

Faculty Publications

Background

Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally.

Methods

We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health …

Fabrication And Characterization Of Non-Equilibrium Plasma-Treated Pvdf Nanofiber Membrane-Based Sensors, Quazi Nahida Sultana, Mujibur Khan, Rajib Mahamud, Mohammadsadegh Saadatzi, Papia Sultana, Tanvir Farouk, Rafael Quirino, Sourav Banerjee

Faculty Publications

The effect of a self-pulsing non-equilibrium plasma discharge on piezoelectric PVDF nanofiber membrane was investigated. The plasma discharge was generated in air with a DC power source, with a discharge current of 0.012 mA, a nominal interelectrode separation of 1 mm, and discharge voltage of ~970 V. In a continuous fabrication process, the electrospinning method was used to generate thin nanofiber membrane with a flow rate of 0.7–1 mL h−1 and 25–27 kV voltage to obtain the nanofiber with high sensitivity and a higher degree of alignment and uniformity over a larger area. Plasma treatment was applied on both single …

Navia: A Program For The Visual Analysis Of Complex Mass Spectra, Daniel Quetschlich, Tim K. Esser, Thomas D. Newport, Francesco Fiorentino, Denis Shutin, Siyun Chen, Rachel Davis, Silvia Lovera, Idlir Liko, Phillip J. Stansfeld, Carol V. Robinson

Faculty Publications

MOTIVATION: Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the spectra obtained. These spectra can be time consuming to tackle through manual assignment and challenging for automated approaches. RESULTS: Native Mass Spectrometry Visual Analyser (NaViA) is a web-based tool to augment the manual process of peak assignment. In addition to matching masses to the stoichiometry of its component subunits it allows raw data processing, assignment and annotation and permits mass …

A Nationwide Population-Based Study On The Association Between Land Transport Accident And Peripheral Vestibular Disorders, Herng-Ching Lin, Sudha Xirasagar Mbbs,Ph.D., Chia-Hui Wang, Yen-Fu Cheng, Tsai-Ching Liu, Tzong-Hann Yang

Faculty Publications

This case-control study aimed to investigate the association of peripheral vestibular disorders (PVD) with subsequent land transport accidents. Data for this study were obtained from Taiwan's National Health Insurance (NHI) dataset. We retrieved 8704 subjects who were newly found to have land transport accidents as cases. Their diagnosis date was used as their index date. Controls were identified by propensity score matching (one per case, n = 8704 controls) from the NHI dataset with their index date being the date of their first health service claim in 2017. Multiple logistic regressions were performed to calculate the prior PVD odds ratio …

Biogenic Sinking Particle Fluxes And Sediment Trap Collection Efficiency At Ocean Station Papa, Margaret Estapa, Ken Buesseler, Collen A. Durkin, Melissa Omand, Claudia Benitez-Nelson, Montserrat Rocca-Martí, Elly Breves, R. P. Kelly, Steve Pike

Faculty Publications

Comprehensive field observations characterizing the biological carbon pump (BCP) provide the foundation needed to constrain mechanistic models of downward particulate organic carbon (POC) flux in the ocean. Sediment traps were deployed three times during the EXport Processes in the Ocean from RemoTe Sensing campaign at Ocean Station Papa in August–September 2018. We propose a new method to correct sediment trap sample contamination by zooplankton “swimmers.” We consider the advantages of polyacrylamide gel collectors to constrain swimmer influence and estimate the magnitude of possible trap biases. Measured sediment trap fluxes of thorium-234 are compared to water column measurements to assess trap …

Development Of Catalytic Combustion And Co2 Capture And Conversion Technology, Zhibin Yang, Ze Lei, Xingyu Xiong, Yiqian Jin, Kui Jiao, Fanglin Chen, Suping Peng

Faculty Publications

Changes are needed to improve the efficiency and lower the CO₂ emissions of traditional coal-fired power generation, which is the main source of global CO₂ emissions. The integrated gasification fuel cell (IGFC) process, which combines coal gasification and high-temperature fuel cells, was proposed in 2017 to improve the efficiency of coal-based power generation and reduce CO₂ emissions. Supported by the National Key R&D Program of China, the IGFC for nearzero CO₂ emissions program was enacted with the goal of achieving near-zero CO₂ emissions based on (1) catalytic combustion of the flue gas from solid oxide …

Beneficial Use Decision Support For Wetlands: Case Study For Mobile Bay, Alabama, Kyle D. Runion, Brandon M. Boyd, Candice D. Piercy, James T. Morris

Faculty Publications

The beneficial use of dredged material (BUDM) for wetland restoration improves coastal wetland resilience and conserves coastal natural infrastructure. Tools, such as biophysical models help coastal managers to assess habitat vulnerability and plan restoration. In this study, the Marsh Equilibrium Model (MEM) will be utilized combined with observed data to predict future conditions and evaluate potential marsh restoration via the BUDM in Mobile Bay, Alabama. A range of site conditions and restoration strategies will be considered and the impacts on dredged material management area (DMMA) volumes will be evaluated. Wetland restoration via thin-layer placement (TLP) of dredged material (DM) restores …

Attitudes Towards A Mindfulness-Based Intervention From African American Women Living With Hiv: A Qualitative Study, Slone Taylor, Shan Qiao Ph.D., Sharon Weissman, Xiaoming Li Ph.D.

Faculty Publications

Introduction: Mindfulness-based interventions train participants to pay attention to their own emotions in the current moment without judging themselves. This study aims to assess the attitudes toward a mindfulness-based stress reduction intervention among African American women living with HIV. Methods: We collected qualitative data from three focus group discussions with 18 African American women living with HIV who were purposely recruited from the Palmetto Health-USC Immunology Center in South Carolina, United States. The participants discussed how they coped with stress, and then were given a presentation on mindfulness-based stress reduction and a sample mindfulness-based stress reduction mini workshop with follow-up …