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High-Energy Emission From A Magnetar Giant Flare In The Sculptor Galaxy, M. Ajello, W. B. Atwood, M. Axelsson, L. Baldini, G. Barbiellini, M. G. Baring, D. Bastieri, R. Bellazzini, A. Berretta, E. Bissaldi, R. D. Blandford, R. Bonino, J. Bregeon, P. Bruel, R. Buehler, E. Burns, S. Buson, R. A. Cameron, P. A. Caraveo, E. Cavazzuti, S. Chen, C. C. Cheung, G. Chiaro, S. Ciprini, D. Costantin, M. Crnogorcevic, S. Cutini, F. D’Ammando, P. De La Torre Luque, F. De Palma, S. W. Digel, N. Di Lalla, L. Di Venere Apr 2021

High-Energy Emission From A Magnetar Giant Flare In The Sculptor Galaxy, M. Ajello, W. B. Atwood, M. Axelsson, L. Baldini, G. Barbiellini, M. G. Baring, D. Bastieri, R. Bellazzini, A. Berretta, E. Bissaldi, R. D. Blandford, R. Bonino, J. Bregeon, P. Bruel, R. Buehler, E. Burns, S. Buson, R. A. Cameron, P. A. Caraveo, E. Cavazzuti, S. Chen, C. C. Cheung, G. Chiaro, S. Ciprini, D. Costantin, M. Crnogorcevic, S. Cutini, F. D’Ammando, P. De La Torre Luque, F. De Palma, S. W. Digel, N. Di Lalla, L. Di Venere

Faculty Publications

Magnetars are the most highly magnetized neutron stars in the cosmos (with magnetic field 1013–1015 G). Giant flares from magnetars are rare, short-duration (about 0.1 s) bursts of hard X-rays and soft γ rays1,2. Owing to the limited sensitivity and energy coverage of previous telescopes, no magnetar giant flare has been detected at gigaelectronvolt (GeV) energies. Here, we report the discovery of GeV emission from a magnetar giant flare on 15 April 2020 (refs. 3,4 and A. J. Castro-Tirado et al., manuscript in preparation). The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope detected GeV γ rays …


Effect Of Serving Plate Types And Color Cues On Liking And Purchase Intent Of Cheese-Flavored Tortilla Chips, Cristhiam Gurdian, Damir Torrico, Bin Li, Witoon Prinyawiwatkul Apr 2021

Effect Of Serving Plate Types And Color Cues On Liking And Purchase Intent Of Cheese-Flavored Tortilla Chips, Cristhiam Gurdian, Damir Torrico, Bin Li, Witoon Prinyawiwatkul

Faculty Publications

No abstract provided.


Evaluation Of Changes In Drug Susceptibility And Population Genetic Structure In Haemonchus Contortus Following Worm Replacement As A Means To Reverse The Impact Of Multiple-Anthelmintic Resistance On A Sheep Farm, Melissa M. George, Adriano F. Vatta, Sue B. Howell, Bob E. Storey, Ciaran J. Mccoy, Adrian J. Wolstenholme, Elizabeth M. Redman, John S. Gilleard, Ray M. Kaplan Apr 2021

Evaluation Of Changes In Drug Susceptibility And Population Genetic Structure In Haemonchus Contortus Following Worm Replacement As A Means To Reverse The Impact Of Multiple-Anthelmintic Resistance On A Sheep Farm, Melissa M. George, Adriano F. Vatta, Sue B. Howell, Bob E. Storey, Ciaran J. Mccoy, Adrian J. Wolstenholme, Elizabeth M. Redman, John S. Gilleard, Ray M. Kaplan

Faculty Publications

A population of Haemonchus contortus that was highly resistant to benzimidazoles and avermectin/milbemycins with a subpopulation that was resistant to levamisole, was replaced with a susceptible laboratory isolate of H. contortus in a flock of sheep. The anthelmintic susceptibility and population genetics of the newly established population were evaluated for 3.5 years using in vivo, in vitro, and molecular methods. Successful replacement of the resistant population with a susceptible population was confirmed using phenotypic and genotypic measurements; larval development assay indicated full anthelmintic susceptibility; albendazole treatment yielded 98.7% fecal egg count reduction; pyrosequence genotyping of single nucleotide polymorphisms in positions …


Envrtype: A Software To Interplay Enviromics And Quantitative Genomics In Agriculture, Germano Costa-Neto, Giovanni Galli, Humberto Fanelli Carvalho, Jose Crossa, Roberto Fritsche-Neto Apr 2021

Envrtype: A Software To Interplay Enviromics And Quantitative Genomics In Agriculture, Germano Costa-Neto, Giovanni Galli, Humberto Fanelli Carvalho, Jose Crossa, Roberto Fritsche-Neto

Faculty Publications

Envirotyping is an essential technique used to unfold the nongenetic drivers associated with the phenotypic adaptation of living organisms. Here, we introduce the EnvRtype R package, a novel toolkit developed to interplay large-scale envirotyping data (enviromics) into quantitative genomics. To start a user-friendly envirotyping pipeline, this package offers: (1) remote sensing tools for collecting (get_weather and extract_GIS functions) and processing ecophysiological variables (processWTH function) from raw environmental data at single locations or worldwide; (2) environmental characterization by typing environments and profiling descriptors of environmental quality (env_typing function), in addition to gathering environmental covariables as quantitative descriptors for predictive purposes (W_matrix …


The Impact Of Short Sleep On Food Reward Processes In Adolescents, Kara Mcrae Duraccio, K. N. Krietsch, N. Zhang, C. Whitacre, T. Howarth, M. Pfeiffer, D. W. Beebe Apr 2021

The Impact Of Short Sleep On Food Reward Processes In Adolescents, Kara Mcrae Duraccio, K. N. Krietsch, N. Zhang, C. Whitacre, T. Howarth, M. Pfeiffer, D. W. Beebe

Faculty Publications

Short sleep has been linked to adolescent obesity risk, but questions remain regarding the dietary mechanisms by which this occurs. We tested whether mildly shortening sleep influences how rewarding and appealing healthy adolescents find several kinds of foods. Eighty-eight healthy adolescents completed a within-subjects crossover sleep experiment comparing 5 days of Short Sleep (6.5 hour sleep opportunity) vs. 5 days of Healthy Sleep (9.5 hour sleep opportunity). Following each condition, adolescents completed measures of food appeal and reinforcing value of food across five food types: sweets/desserts, fruits/vegetables, lean meats/eggs, fast food entrees, and processed snacks. Adolescents averaged 2.2 hours/night longer …


Gwtc-2: Compact Binary Coalescences Observed By Ligo And Virgo During The First Half Of The Third Observing Run, Ligo Scientific Collaboration, Virgo Collaboration, Tiffany Z. Summerscales Apr 2021

Gwtc-2: Compact Binary Coalescences Observed By Ligo And Virgo During The First Half Of The Third Observing Run, Ligo Scientific Collaboration, Virgo Collaboration, Tiffany Z. Summerscales

Faculty Publications

We report on gravitational-wave discoveries from compact binary coalescences detected by Advanced LIGO and Advanced Virgo in the first half of the third observing run (O3a) between 1 April 2019 15∶00 UTC and 1 October 2019 15∶00 UTC. By imposing a false-alarm-rate threshold of two per year in each of the four search pipelines that constitute our search, we present 39 candidate gravitational-wave events. At this threshold, we expect a contamination fraction of less than 10%. Of these, 26 candidate events were reported previously in near-real time through gamma-ray coordinates network notices and circulars; 13 are reported here for the …


Rehabilitating Charge Bargaining, Nancy Amoury Combs Apr 2021

Rehabilitating Charge Bargaining, Nancy Amoury Combs

Faculty Publications

Nobody likes plea bargaining. Scholars worldwide have excoriated the practice, calling it coercive and unjust, among other pejorative adjectives. Despite its unpopularity, plea bargaining constitutes a central component of the American criminal justice system, and the United States has exported the practice to a host of countries worldwide. Indeed, plea bargaining has even appeared at international criminal tribunals, created to prosecute genocide and crimes against humanity--the gravest crimes known to humankind. Although all forms of plea bargaining are unpopular, commentators reserve their harshest criticism for charge bargaining because charge bargaining is said to distort the factual basis of the defendant's …


How To Look Like A Lawyer, Ann Juliano Apr 2021

How To Look Like A Lawyer, Ann Juliano

Faculty Publications

Law schools often claim that they are teaching students “how to think like a lawyer.” What is less touted, however, is that students are learning how to look like a lawyer. They receive this message from multiple sources (faculty, alumni, peers, the career office) concerning a variety of situations: class, interviews, moot court, trial team, symposia and conferences. For law students who are first generation, these sources may be the only avenue (apart from the entertainment industry) of determining how to look like a lawyer. For law students who are transgender or gender non-binary, dress code advice dispensed along men/women …


Tax Administration And Racial Justice: The Illegal Denial Of Tax Based Pandemic Relief To The Nation's Incarcerated, Leslie Book Apr 2021

Tax Administration And Racial Justice: The Illegal Denial Of Tax Based Pandemic Relief To The Nation's Incarcerated, Leslie Book

Faculty Publications

No abstract provided.


Are Granulins Copper Sequestering Proteins?, Anukool A. Bhopatkar, Vijayaraghavan Rangachari Apr 2021

Are Granulins Copper Sequestering Proteins?, Anukool A. Bhopatkar, Vijayaraghavan Rangachari

Faculty Publications

Granulins (GRN 1-7) are short (~6 kDa), cysteine-rich proteins that are generated upon the proteolytic processing of progranulin (PGRN). These peptides, along with their precursor, have been implicated in multiple pathophysiological roles, especially in neurodegenerative diseases. Previously we showed that GRN-3 and GRN-5 are fully disordered in the reduced form implicating redox sensitive attributes to the proteins. Redox-based modulations are often carried out by metalloproteins in mitigating oxidative stress and maintaining metal-homeostasis within cells. To probe whether GRNs play a role in metal sequestration, we tested the metal binding propensity of the reduced forms of GRNs −3 and − 5 …


Heterogeneous Co2And Ch4Content Of Glacial Meltwater From The Greenland Ice Sheet And Implications For Subglacial Carbon Processes, Andrea J. Pain, Jonathan B. Martin, Ellen E. Martin, Åsa K. Rennermalm, Shaily Rahman Apr 2021

Heterogeneous Co2And Ch4Content Of Glacial Meltwater From The Greenland Ice Sheet And Implications For Subglacial Carbon Processes, Andrea J. Pain, Jonathan B. Martin, Ellen E. Martin, Åsa K. Rennermalm, Shaily Rahman

Faculty Publications

Accelerated melting of the Greenland Ice Sheet has increased freshwater delivery to the Arctic Ocean and amplified the need to understand the impact of Greenland Ice Sheet meltwater on Arctic greenhouse gas budgets. We evaluate subglacial discharge from the Greenland Ice Sheet for carbon dioxide (CO2) and methane (CH4) concentrations and δ13C values and use geochemical models to evaluate subglacial CH4 and CO2 sources and sinks. We compare discharge from southwest (a sub-catchment of the Isunnguata Glacier, sub-Isunnguata, and the Russell Glacier) and southern Greenland (Kiattut Sermiat). Meltwater CH4 concentrations vary …


Hybrid Modeling And Prediction Of Oyster Norovirus Outbreaks, Shima Shamkhali Chenar, Zhiqiang Deng Apr 2021

Hybrid Modeling And Prediction Of Oyster Norovirus Outbreaks, Shima Shamkhali Chenar, Zhiqiang Deng

Faculty Publications

This paper presents a hybrid model for predicting oyster norovirus outbreaks by combining the Artificial Neural Networks (ANNs) and Principal Component Analysis (PCA) methods and using the Moderate Resolution Imaging Spectroradiometer (MODIS) satellite remote-sensing data. Specifically, 10 years (2007-2016) of cloud-free MODIS Aqua data for water leaving reflectance and environmental data were extracted from the center of each oyster harvest area. Then, the PCA was utilized to compress the size of the MODIS Aqua data. An ANN model was trained using the first 4 years of the data from 2007 to 2010 and validated using the additional 6 years of …


Hydrothermal Synthesis And Structural Investigation Of A Crystalline Uranyl Borosilicate, Kristen A. Pace, Vladislav V. Klepov, Mark D. Smith, Travis Williams, Gregory Morrison, Jochen A. Lauterbach, Scott T. Misture, Hans Conrad Zur Loye Apr 2021

Hydrothermal Synthesis And Structural Investigation Of A Crystalline Uranyl Borosilicate, Kristen A. Pace, Vladislav V. Klepov, Mark D. Smith, Travis Williams, Gregory Morrison, Jochen A. Lauterbach, Scott T. Misture, Hans Conrad Zur Loye

Faculty Publications

The relevance of multidimensional and porous crystalline materials to nuclear waste reme-diation and storage applications has motivated exploratory research focused on materials discovery of compounds, such as actinide mixed-oxoanion phases, which exhibit rich structural chemistry. The novel phase K1.8 Na1.2 [(UO2)BSi4 O12 ] has been synthesized using hydrothermal methods, rep-resenting the first example of a uranyl borosilicate. The three-dimensional structure crystallizes in the orthorhombic space group Cmce with lattice parameters a = 15.5471(19) Å, b = 14.3403(17) Å, c = 11.7315(15) Å, and V = 2615.5(6) Å3, and is composed of UO6 octahedra linked by [BSi4 O12 ]5− chains to …


Discursive Power And Resistance In The Information Worlds Maps Of Lgbtqia+ Community Leaders, Vanessa Kitzie, Travis L. Wagner, Alexander N. Vera Apr 2021

Discursive Power And Resistance In The Information Worlds Maps Of Lgbtqia+ Community Leaders, Vanessa Kitzie, Travis L. Wagner, Alexander N. Vera

Faculty Publications

Purpose: This qualitative study explores how discursive power shapes South Carolina LGBTQIA+ communities' health information practices and how participants resist this power. Design/methodology/approach: Twenty-eight LGBTQIA+ community leaders from South Carolina engaged in semi-structured interviews and information worlds mapping – a participatory arts-based elicitation technique – to capture the context underlying how they and their communities create, seek, use, and share health information. We focus on the information worlds maps for this paper, employing situational analysis – a discourse analytic method for visual data – to analyze them. Findings: Six themes emerged describing how discursive power operates both within and outside …


Zn Acceptors In Β-Ga2O3 Crystals, Timothy D. Gustafson, J. Jesenovec, Christopher A. Lenyk, Nancy C. Giles, J. S. Mccloy, M. Mccluskey, Larry E. Halliburton Apr 2021

Zn Acceptors In Β-Ga2O3 Crystals, Timothy D. Gustafson, J. Jesenovec, Christopher A. Lenyk, Nancy C. Giles, J. S. Mccloy, M. Mccluskey, Larry E. Halliburton

Faculty Publications

Electron paramagnetic resonance (EPR) is used to identify and characterize neutral zinc acceptors in Zn-doped β-Ga2O3 crystals. Two EPR spectra are observed at low temperatures, one from Zn ions at tetrahedral Ga(1) sites (the Zn0Ga1 acceptor) and one from Zn ions at octahedral Ga(2) sites (the Zn0Ga2 acceptor). These Zn acceptors are small polarons, with the unpaired spin localized in each case on a threefold coordinated oxygen O(I) ion adjacent to the Zn ion. Resolved hyperfine interactions with neighboring 69Ga and 71Ga nuclei allow the EPR spectra from the two acceptors …


Protocols For Assessing Transformation Rates Of Nitrous Oxide In The Water Column, Annie Bourbonnais, Claudia Frey, Xin Sun, Laura A. Bristow, Amal Jayakumar, Nathaniel E. Ostrom, Karen L. Casciotti, Bess B. Ward Apr 2021

Protocols For Assessing Transformation Rates Of Nitrous Oxide In The Water Column, Annie Bourbonnais, Claudia Frey, Xin Sun, Laura A. Bristow, Amal Jayakumar, Nathaniel E. Ostrom, Karen L. Casciotti, Bess B. Ward

Faculty Publications

Nitrous oxide (N2O) is a potent greenhouse gas and an ozone destroying substance. Yet, clear step-by-step protocols to measure N2O transformation rates in freshwater and marine environments are still lacking, challenging inter-comparability efforts. Here we present detailed protocols currently used by leading experts in the field to measure water-column N2O production and consumption rates in both marine and other aquatic environments. We present example 15N-tracer incubation experiments in marine environments as well as templates to calculate both N2O production and consumption rates. We discuss important considerations and recommendations regarding (1) precautions to prevent oxygen (O2) contamination during low-oxygen and anoxic …


Ion Gnss Software-Defined Radio Metadata Standard, Sanjeev Gunawardena, Thomas Pany, James Curran Apr 2021

Ion Gnss Software-Defined Radio Metadata Standard, Sanjeev Gunawardena, Thomas Pany, James Curran

Faculty Publications

The past several years have seen a proliferation of software‐defined radio (SDR) data collection systems and processing platforms designed for or applicable to satellite navigation (satnav) applications. These systems necessarily produce datasets in a wide range of different formats. To correctly interpret this SDR data, essential information such as the packed sample format and sampling rate is needed. Communicating this metadata between creators and users has historically been an ad‐hoc, cumbersome, and error‐prone process. To address this issue, the satnav SDR community developed a metadata standard and normative software library to automate this process, thus simplifying the exchange of datasets …


Restorative Justice And The School-To-Prison Pipeline: A Review Of Existing Literature, Hani Morgan Mar 2021

Restorative Justice And The School-To-Prison Pipeline: A Review Of Existing Literature, Hani Morgan

Faculty Publications

Black students experience out-of-school suspensions at a higher rate than other students. The higher rate at which these students are suspended is believed to contribute to a school-to-prison pipeline. This review article is designed to enhance the understanding of this problem by focusing on the factors that play a part in the school-to-prison pipeline. A purposeful sample of recently published literature by some of the leading scholars in this area was selected for analysis. Some studies indicate that school personnel may be biased in the ways they respond to Black students. The lack of teacher preparation and support has been …


Feasibility Of Integrating Survivors Of Stroke Into Cardiac Rehabilitation: A Mixed Methods Pilot Study, Elizabeth W. Regan, Reed Handlery, Jill C. Stewart, Joseph Lee Pearson Ms,Drph, Sara Wilcox Ph.D., Stacy Fritz Mar 2021

Feasibility Of Integrating Survivors Of Stroke Into Cardiac Rehabilitation: A Mixed Methods Pilot Study, Elizabeth W. Regan, Reed Handlery, Jill C. Stewart, Joseph Lee Pearson Ms,Drph, Sara Wilcox Ph.D., Stacy Fritz

Faculty Publications

Background Survivors of stroke are often deconditioned and have limited opportunities for exercise post-rehabilitation. Cardiac Rehabilitation (CR), a structured exercise program offered post-cardiac event in the United States (U.S.), may provide an opportunity for continued exercise.

The purpose of this study was to examine the feasibility of integrating survivors of stroke into an existing, hospital-based CR program through an assessment of (1) recruitment, uptake and retention, (2) adherence and fidelity, (3) acceptability and (4) safety.

Methods A mixed methods design combined a single group, pre-post design, pilot feasibility study with an imbedded qualitative inquiry. Survivors of stroke were recruited into …


Changes In Soil Chemistry And Foliar Metabolism Of Himalayan Cedar (Cedrus Deodara) And Himalayan Spruce (Picea Smithiana) Along An Elevational Gradient At Kufri, Hp, India: The Potential Roles Of Regional Pollution And Localized Grazing, Rakesh Minocha, Alexandra R. Contosta, Gregory B. Lawrence, Ravinder K. Kohli, Subhash C. Minocha, Stephanie Long Mar 2021

Changes In Soil Chemistry And Foliar Metabolism Of Himalayan Cedar (Cedrus Deodara) And Himalayan Spruce (Picea Smithiana) Along An Elevational Gradient At Kufri, Hp, India: The Potential Roles Of Regional Pollution And Localized Grazing, Rakesh Minocha, Alexandra R. Contosta, Gregory B. Lawrence, Ravinder K. Kohli, Subhash C. Minocha, Stephanie Long

Faculty Publications

We investigated changes in soil chemistry and foliar metabolism of Himalayan cedar [Cedrus deodara (Roxb. Ex Lamb.) G.Don] and Himalayan spruce [Picea smithiana (Wall.) Boiss] trees along a steep elevational gradient in the lower Himalayan Mountains at Kufri, Himachal Pradesh (HP), India. The foliar and soil samples were collected from four locations along a 300 m elevational gradient at ridge, high-, mid-, and low-elevation sites within the forested Shimla Water Catchment Wildlife Sanctuary that provides water for the city of Shimla, HP,. Observations at the time of sampling revealed that the high-elevation site was being heavily grazed. Soils collected at …


“When They Say Weed Causes Depression, But It’S Your Fav Antidepressant”: Knowledge-Aware Attention Framework For Relationship Extraction, Shweta Yadav, Usha Lokala, Raminta Daniulaityte, Krishnaprasad Thirunarayan, Francois Lamy, Amit P. Sheth Mar 2021

“When They Say Weed Causes Depression, But It’S Your Fav Antidepressant”: Knowledge-Aware Attention Framework For Relationship Extraction, Shweta Yadav, Usha Lokala, Raminta Daniulaityte, Krishnaprasad Thirunarayan, Francois Lamy, Amit P. Sheth

Faculty Publications

With the increasing legalization of medical and recreational use of cannabis, more research is needed to understand the association between depression and consumer behavior related to cannabis consumption. Big social media data has potential to provide deeper insights about these associations to public health analysts. In this interdisciplinary study, we demonstrate the value of incorporating domain-specific knowledge in the learning process to identify the relationships between cannabis use and depression. We develop an end-to-end knowledge infused deep learning framework (Gated-K-BERT) that leverages the pre-trained BERT language representation model and domain-specific declarative knowledge source (Drug Abuse Ontology) to jointly extract entities …


Using Multiple Ecological Models To Inform Environmental Decision-Making, Kristy A. Lewis, Kenneth A. Rose, Kim De Mutsert, Shaye Sable, Cameron Ainsworth, Damian C. Brady, Howard Townsend Mar 2021

Using Multiple Ecological Models To Inform Environmental Decision-Making, Kristy A. Lewis, Kenneth A. Rose, Kim De Mutsert, Shaye Sable, Cameron Ainsworth, Damian C. Brady, Howard Townsend

Faculty Publications

Coastal ecosystems are experiencing degradation from compound impacts of climate change and multiple anthropogenic disturbances. These pressures often act synergistically and complicate designing effective conservation measures; consequently, large-scale coastal restoration actions become a wicked problem. The purpose of this study was to use two different food web models in a coordinated manner to inform resource managers in their assessment of the ecological effects of a large-scale marsh restoration project. A team was formed that included the model developers and outside scientists, who were asked to use available model results of the calibrated simulations of an Ecopath with Ecosim (EwE) model …


Characterization, Bio-Uptake And Toxicity Of Polymer-Coated Silver Nanoparticles And Their Interaction With Human Peripheral Blood Mononuclear Cells, Sahar Pourhoseini, Reilly T. Enos, Angela E. Murphy, Bo Cai Ph.D., Jamie Lead Mar 2021

Characterization, Bio-Uptake And Toxicity Of Polymer-Coated Silver Nanoparticles And Their Interaction With Human Peripheral Blood Mononuclear Cells, Sahar Pourhoseini, Reilly T. Enos, Angela E. Murphy, Bo Cai Ph.D., Jamie Lead

Faculty Publications

Silver nanoparticles (AgNPs) are widely used in medical applications due to their antibacterial and antiviral properties. Despite the extensive study of AgNPs, their toxicity and their effect on human health is poorly understood, as a result of issues such as poor control of NP properties and lack of proper characterization. The aim of this study was to investigate the combined characterization, bio-uptake, and toxicity of well-characterized polyvinylpyrrolidone (PVP)-coated AgNPs in exposure media during exposure time using primary human cells (peripheral blood mononuclear cells (PBMCs)). AgNPs were synthesized in-house and characterized using a multimethod approach. Results indicated the transformation of NPs …


Aerosol Ph Indicator And Organosulfate Detectability From Aerosol Mass Spectrometry Measurements, Melinda K. Schueneman, Benjamin A. Nault, Pedro Campuzano-Jost, Duseong S. Jo, Douglas A. Day, Jason C. Schroder, Brett B. Palm, Alma Hodzic, Jack E. Dibb, Jose L. Jimenez Mar 2021

Aerosol Ph Indicator And Organosulfate Detectability From Aerosol Mass Spectrometry Measurements, Melinda K. Schueneman, Benjamin A. Nault, Pedro Campuzano-Jost, Duseong S. Jo, Douglas A. Day, Jason C. Schroder, Brett B. Palm, Alma Hodzic, Jack E. Dibb, Jose L. Jimenez

Faculty Publications

Aerosol sulfate is a major component of submicron particulate matter (PM1). Sulfate can be present as inorganic (mainly ammonium sulfate, AS) or organosulfate (OS). Although OS is thought to be a smaller fraction of total sulfate in most cases, recent literature argues that this may not be the case in more polluted environments. Aerodyne aerosol mass spectrometers (AMSs) measure total submicron sulfate, but it has been difficult to apportion AS vs. OS as the detected ion fragments are similar. Recently, two new methods have been proposed to quantify OS separately from AS with AMS data. We use observations collected during …


A Modular System For Treating Moving Anatomical Targets With Scanned Ion Beams At Multiple Facilities: Pre-Clinical Testing For Quality And Safety Of Beam Delivery, Michelle Lis, Wayne Newhauser, Marco Donetti, Moritz Wolf, Timo Steinsberger, Athena Paz, Marco Durante, Christian Graeff Mar 2021

A Modular System For Treating Moving Anatomical Targets With Scanned Ion Beams At Multiple Facilities: Pre-Clinical Testing For Quality And Safety Of Beam Delivery, Michelle Lis, Wayne Newhauser, Marco Donetti, Moritz Wolf, Timo Steinsberger, Athena Paz, Marco Durante, Christian Graeff

Faculty Publications

Background: Quality management and safety are integral to modern radiotherapy. New radiotherapy technologies require new consensus guidelines on quality and safety. Established analysis strategies, such as the failure modes and effects analysis (FMEA) and incident learning systems have been developed as tools to assess the safety of several types of radiation therapies. An extensive literature documents the widespread application of risk analysis methods to photon radiation therapy. Relatively little attention has been paid to performing risk analyses of nascent radiation therapy systems to treat moving tumors with scanned heavy ion beams. The purpose of this study was to apply a …


Coordination And Control – Limits In Standard Representations Of Multi-Reservoir Operations In Hydrological Modeling, Charles Rouge, Patrick M. Reed, Danielle S. Grogan, Shan Zuidema, Alexander Prusevich, Stanley Glidden, Jonathan R. Lamontagne, Richard B. Lammers Mar 2021

Coordination And Control – Limits In Standard Representations Of Multi-Reservoir Operations In Hydrological Modeling, Charles Rouge, Patrick M. Reed, Danielle S. Grogan, Shan Zuidema, Alexander Prusevich, Stanley Glidden, Jonathan R. Lamontagne, Richard B. Lammers

Faculty Publications

Major multi-reservoir cascades represent a primary mechanism for dealing with hydrologic variability and extremes within institutionally complex river basins worldwide. These coordinated management processes fundamentally reshape water balance dynamics. Yet, multi-reservoir coordination processes have been largely ignored in the increasingly sophisticated representations of reservoir operations within large-scale hydrological models. The aim of this paper is twofold, namely (i) to provide evidence that the common modeling practice of parameterizing each reservoir in a cascade independently from the others is a significant approximation and (ii) to demonstrate potential unintended consequences of this independence approximation when simulating the dynamics of hydrological extremes in …


Relationship Between Diet Quality Scores And The Risk Of Frailty And Mortality In Adults Across A Wide Age Spectrum, Kulapong Jayanama, Olga Theou, Judith Godin, Leah Cahill, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert, Michael David Wirth Msph, Phd, Yong-Moon Park, Teresa T. Fung, Kenneth Rockwood Mar 2021

Relationship Between Diet Quality Scores And The Risk Of Frailty And Mortality In Adults Across A Wide Age Spectrum, Kulapong Jayanama, Olga Theou, Judith Godin, Leah Cahill, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert, Michael David Wirth Msph, Phd, Yong-Moon Park, Teresa T. Fung, Kenneth Rockwood

Faculty Publications

Background

Beyond intakes of total energy and individual nutrient, eating patterns may influence health, and thereby the risk of adverse outcomes. How different diet measures relate to frailty—a general measure of increased vulnerability to unfavorable health outcomes—and mortality risk, and how this might vary across the life course, is not known. We investigated the associations of five dietary indices (Nutrition Index (NI), the energy-density Dietary Inflammatory Index (E-DII™), Healthy Eating Index-2015 (HEI-2015), Mediterranean Diet Score (MDS), and Dietary Approaches to Stop Hypertension (DASH)) with frailty and mortality.

Methods

We included 15,249 participants aged ≥ 20 years from the 2007–2012 cohorts …


Achieving The Shot-Noise Limit Using Experimental Multi-Shot Digital Holography Data, Douglas E. Thornton, Cameron J. Radosevich, Samuel Horst, Mark F. Spencer Mar 2021

Achieving The Shot-Noise Limit Using Experimental Multi-Shot Digital Holography Data, Douglas E. Thornton, Cameron J. Radosevich, Samuel Horst, Mark F. Spencer

Faculty Publications

In this paper, we achieve the shot-noise limit using straightforward image-post-processing techniques with experimental multi-shot digital holography data (i.e., off-axis data composed of multiple noise and speckle realizations). First, we quantify the effects of frame subtraction (of the mean reference-only frame and the mean signal-only frame from the digital-hologram frames), which boosts the signal-to-noise ratio (SNR) of the baseline dataset with a gain of 2.4 dB. Next, we quantify the effects of frame averaging, both with and without the frame subtraction. We show that even though the frame averaging boosts the SNR by itself, the frame subtraction and the stability …


Controls For A Nonlinear System Arising In Vision-Based Landing Of Airliners, Laurent Burlion, Victor Gibert, Michael Malisoff, Frederic Mazenc Mar 2021

Controls For A Nonlinear System Arising In Vision-Based Landing Of Airliners, Laurent Burlion, Victor Gibert, Michael Malisoff, Frederic Mazenc

Faculty Publications

We use a novel backstepping method to solve a stabilization problem for a nonlinear system with delayed sampled outputs that are not accurately measured. We provide an application to a system arising in vision-based landing of airliners that includes coupling between the lateral and longitudinal dynamics, for which we provide performance guarantees in the presence of the delay, nonlinearity, and sampling. Our major contributions are (a) designs of lateral and longitudinal controls for our nonlinear model of an aircraft landing on an unequipped runway, (b) mathematical proofs that our controls ensure that the aircraft being modeled achieves desired alignment with …


The Connecticut Second Chance​ ​Pardon​ ​Gap, Colleen Chien, Hithesh Bathala, Prajakta Pingale, Evan Hastings, Adam Osmond Mar 2021

The Connecticut Second Chance​ ​Pardon​ ​Gap, Colleen Chien, Hithesh Bathala, Prajakta Pingale, Evan Hastings, Adam Osmond

Faculty Publications

Connecticut Law Chapter 961a Section 54-142a, Chapter 960a Sections 54-76o and 54-130a allows individuals whose criminal records meet certain conditions to apply for pardons of their past criminal convictions. Proposed Bill SB 403,2 Connecticut’s “Clean Slate” Act, likewise would provide for automatic erasure of the records of a subset of individuals who can apply for pardons. Ascertaining, then applying existing pardons law and proposed “Clean Slate” law to a sample of 309,827 criminal histories of individuals with Connecticut convictions records, and then extrapolating to the estimated population of 450K individuals in the state with convictions,3 we estimate the share and …