Digital Commons Network^™

Estimating Cardiorespiratory Fitness Without Exercise Testing Or Physical Activity Status In Healthy Adults: Regression Model Development And Validation, Robert Sloan, Marco Visentini-Scarzanella, Susumu Sawada, Xuemei Sui M.D., M.P.H., Ph.D.

Faculty Publications

Background: Low cardiorespiratory fitness (CRF) is an independent predictor of morbidity and mortality. Most health care settings use some type of electronic health record (EHR) system. However, many EHRs do not have CRF or physical activity data collected, thereby limiting the types of investigations and analyses that can be done.

Objective: This study aims to develop a nonexercise equation to estimate and classify CRF (in metabolic equivalent tasks) using variables commonly available in EHRs.

Methods: Participants were 42,676 healthy adults (female participants: n=9146, 21.4%) from the Aerobics Center Longitudinal Study examined from 1974 to 2005. The nonexercise estimated CRF was …

Prisoners Of Scale: Downscaling Community Resilience Measurements For Enhanced Use, Sahar Derakshan, Leah Blackwood, Margot Habets, Julia F. Effgen, Susan L. Cutter

Faculty Publications

As improved data availability and disaster resilience knowledge help progress community resilience quantification schemes, spatial refinements of the associated empirical methods become increasingly crucial. Most existing empirically based indicators in the U.S. use county-level data, while qualitatively based schemes are more locally focused. The process of replicating resilience indices at a sub-county level includes a comprehensive study of existing databases, an evaluation of their conceptual relevance in the framework of resilience capitals, and finally, an analysis of the statistical significance and internal consistency of the developed metrics. Using the U.S. Gulf Coast region as a test case, this paper demonstrates …

A Preliminary Study Of Proinflammatory Cytokines And Depression Following West Nile Virus Infection, Allison Lino, Timothy A. Erickson, Melissa Nolan Ph.D., Mph, Kristy O. Murray, Shannon E. Ronca

Faculty Publications

West Nile virus (WNV) is a neurotropic flavivirus that can cause acute febrile illness leading to neuroinvasive disease. Depression is a well-described outcome following infection, but the underlying pathogenic mechanisms are unknown. Proinflammatory cytokines play important roles in WNV infection, but their role in depression post-WNV remains unstudied. This research aimed to retrospectively evaluate associations between proinflammatory cytokines and new onset depression in a WNV cohort. Participants with asymptomatic WNV infection were significantly less likely to report new onset depression when compared to those with symptomatic disease. Participants with encephalitis and obesity were significantly more likely to report new onset …

Perceptions Of Hazing Among Young Male United States Military Service Members: A Qualitative Analysis, Elizabeth C. Metzger, Jasmin N. Bennett, Cristobal S. Berry-Caban, Elizabeth J. Allan, Christopher J. Guenthner, Bryce M. Meerhaeghe, Brian Borsari, Donna M. Kazemi Phd, Rn, Cne, Fiaan, Lindsay M. Orchowski

Faculty Publications

This study examines hazing among a sample of young male service members in the United States (US) military. Individual semi-structured interviews were conducted with active duty service members (N = 10) aged 18 to 24 at a large Southeastern US Army post to examine their conceptualization of hazing. Thematic analysis revealed three emergent themes: (1) the definition of hazing and hazing behaviors; (2) the ritualistic nature of hazing; and (3) the sexual nature of hazing. Most participants provided their own definition of hazing. One participant had difficulty in differentiating between hazing and bullying, the others had distinct definitions as …

Delineating The Role Of The Msaabcr Operon In Staphylococcal Overflow Metabolism, Gc Bibek, Gyan S. Sahukhal, Mohamed O. Elasri

Faculty Publications

Staphylococcus aureus is an important human pathogen that can infect almost every organ system, resulting in a high incidence of morbidity and mortality. The msaABCR operon is an important regulator of several staphylococcal phenotypes, including biofilm development, cell wall crosslinking, antibiotic resistance, oxidative stress, and acute and chronic implant-associated osteomyelitis. Our previous study showed that, by modulating murein hydrolase activity, the msaABCR operon negatively regulates the proteases that govern cell death. Here, we report further elucidation of the mechanism of cell death, which is regulated by the msaABCR operon at the molecular level in the USA300 LAC strain. We showed …

Climate Change Reshuffles Northern Species Within Their Niches, Laura H. Antao, Benjamin Weigel, Giovanni Strona, Maria Hallfors, Elina Kaarlejarvi, Tad Dallas, Oystein H. Opedal, Janne Heliola, Heikki Henttonen, Otso Huitu, Erkki Korpimaki, Mikko Kuussaari, Aleksi Lehikoinen, Reima Leinonen, Andreas Lindén, Paivi Merila, Hannu Pietianinen, Juha Poyry, Maija Salemaa, Tiina Tonteri, Kristiina Vuorio, Otso Ovaskainen, Marjo Saastamoinen, Jarno Vanhatalo, Tomas Roslin, Anna-Liisa Laine

Faculty Publications

Climate change is a pervasive threat to biodiversity. While range shifts are a known consequence of climate warming contributing to regional community change, less is known about how species’ positions shift within their climatic niches. Furthermore, whether the relative importance of different climatic variables prompting such shifts varies with changing climate remains unclear. Here we analysed four decades of data for 1,478 species of birds, mammals, butterflies, moths, plants and phytoplankton along a 1,200 km high latitudinal gradient. The relative importance of climatic drivers varied non-uniformly with progressing climate change. While species turnover among decades was limited, the relative position …

Computational Methods To Simulate Molten Salt Thermophysical Properties, Talmage Porter, Michael M. Vaka, Parker Steenblik, Dennis Della Corte

Faculty Publications

Molten salts are important thermal conductors used in molten salt reactors and solar applications. To use molten salts safely, accurate knowledge of their thermophysical properties is necessary. However, it is experimentally challenging to measure these properties and a comprehensive evaluation of the full chemical space is unfeasible. Computational methods provide an alternative route to access these properties. Here, we summarize the developments in methods over the last 70 years and cluster them into three relevant eras. We review the main advances and limitations of each era and conclude with an optimistic perspective for the next decade, which will likely be …

A Century-Long Trajectory Of Phosphorus Loading And Export From Mississippi River Basin To The Gulf Of Mexico: Contributions Of Multiple Environmental Changes, Zihao Bian, Shufen Pan, Zhuonan Wang, Yuanzhi Yao, Rongting Xu, Hao Shi, Latif Kalin, Christopher Anderson, Dubravko Justic, Steven Lohrenz, Hanqin Tian

Faculty Publications

Phosphorus (P) control is critical to mitigating eutrophication in aquatic ecosystems, but the effectiveness of controlling P export from soils has been limited by our poor understanding of P dynamics along the land-ocean aquatic continuum as well as the lack of well-developed process models that effectively couple terrestrial and aquatic biogeochemical P processes. Here, we coupled riverine P biogeochemical processes and water transport with terrestrial processes within the framework of the Dynamic Land Ecosystem Model to assess how multiple environmental changes, including fertilizer and manure P uses, land use, climate, and atmospheric CO2, have affected the long-term dynamics of P …

The Lived Experience Of Health Insurance: An Analysis And Proposal For Reform, Jacqueline R. Fox

Faculty Publications

People are carrying tens of billions of dollars of medical debt, much of it in collections. We delay going to the Emergency Department while having a heart attack because it may cost too much. Doctors try to help insured patients find the best coupon to offset the high copayment for a necessary prescription drug. For inexpensive drugs, insurers make a profit by clawing back copayments that exceed what the drug costs. People who are already arbitrarily disadvantaged because of race, gender, health status, LGBTQ status, obesity, etc. are disproportionately burdened by all of this.

No one would design a system …

Phylogenetic Characterization And Genome Sequence Analysis Of Burkholderia Glumae Strains Isolated In Thailand As The Causal Agent Of Rice Bacterial Panicle Blight, Nootjarin Jungkhun, Antonio Roberto Gomes De Farias, Jutatape Watcharachaiyakup, Nuttima Kositcharoenkul, Jong Hyun Ham, Sujin Patarapuwadol

Faculty Publications

Burkholderia glumae is one of the most critical rice-pathogenic bacteria, and it causes bacterial panicle blight (BPB) in rice plants. In 2017, BPB symptoms were observed from rice fields in Chiang Rai, Northern Thailand. Sixty-one isolates obtained from the symptomatic panicles of rice were initially identified as B. glumae by polymerase chain reaction (PCR) using species-specific primers. Among them, six selected strains isolated from the susceptible japonica rice cultivar DOA2 were characterized in terms of morpho-physiology, pathology, phylogenetics, and genomics. Our genome sequence analysis of the six selected strains revealed the presence of multiple prophages, which may reflect the high …

Interindividual Variation In Maximum Aerobic Metabolism Varies With Gill Morphology And Myocardial Bioenergetics In Gulf Killifish, Bernard B. Rees, Jessica E. Reemeyer, Brian A. Irving

Faculty Publications

This study asked whether interindividual variation in maximum and standard aerobic metabolic rates of the Gulf killifish, Fundulus grandis, correlates with gill morphology and cardiac mitochondrial bioenergetics, traits reflecting critical steps in the O2 transport cascade from the environment to the tissues. Maximum metabolic rate (MMR) was positively related to body mass, total gill filament length and myocardial oxygen consumption during maximum oxidative phosphorylation (multiple R2=0.836). Standard metabolic rate (SMR) was positively related to body mass, total gill filament length and myocardial oxygen consumption during maximum electron transport system activity (multiple R2=0.717). After controlling for body mass, individuals with longer …

Novel Approaches To Environmental Monitoring And Control Of Listeria Monocytogenes In Food Production Facilities, Priyanka Gupta, Achyut Adhikari

Faculty Publications

Listeria monocytogenes is a serious public health hazard responsible for the foodborne illness listeriosis. L. monocytogenes is ubiquitous in nature and can become established in food production facilities, resulting in the contamination of a variety of food products, especially ready-to-eat foods. Effective and risk-based environmental monitoring programs and control strategies are essential to eliminate L. monocytogenes in food production environments. Key elements of the environmental monitoring program include (i) identifying the sources and prevalence of L. monocytogenes in the production environment, (ii) verifying the effectiveness of control measures to eliminate L. monocytogenes, and (iii) identifying the areas and activities to …

Passive Laser Power Stabilization Via An Optical Spring, Torrey Cullen, Scott Aronson, Ron Pagano, Marina Trad Nery, Henry Cain, Jonathon Cripe, Garrett D. Cole, Safura Sharifi, Nancy Aggarwal, Benno Willke, Thomas Corbitt

Faculty Publications

Metrology experiments can be limited by the noise produced by the laser involved via small fluctuations in the laser’s power or frequency. Typically, active power stabilization schemes consisting of an in-loop sensor and a feedback control loop are employed. Those schemes are fundamentally limited by shot noise coupling at the in-loop sensor. In this Letter, we propose to use the optical spring effect to passively stabilize the classical power fluctuations of a laser beam. In a proof of principle experiment, we show that the relative power noise of the laser is stabilized from approximately 2 × 10⁻⁵ Hz^{−1 …}

Thinking Outside The Box: Numerical Relativity With Particles, Stephan Rosswog, Peter Diener, Francesco Torsello

Faculty Publications

The observation of gravitational waves from compact objects has now become an active part of observational astronomy. For a sound interpretation, one needs to compare such observations against detailed Numerical Relativity simulations, which are essential tools to explore the dynamics and physics of compact binary mergers. To date, essentially all simulation codes that solve the full set of Einstein’s equations are performed in the framework of Eulerian hydrodynamics. The exception is our recently developed Numerical Relativity code SPHINCS_BSSN which solves the commonly used BSSN formulation of the Einstein equations on a structured mesh and the matter equations via Lagrangian particles. …

The Lsu Campus Mounds, With Construction Beginning At ~11,000 Bp, Are The Oldest Known Extant Man-Made Structures In The Americas, Brooks B. Ellwood, Sophie Warny, Rebecca A. Hackworth, Suzanne H. Ellwood, Jonathan H. Tomkin, Samuel J. Bentley, Dewitt H. Braud, Geoffrey C. Clayton

Faculty Publications

Radiocarbon dating of the two LSU Campus Mounds (16EBR6) indicates that the construction of one, Mound B, began at ~11,000 BP, making Mound B the oldest known and intact manmade structure in the Americas. The age analyses preesented here are based on thirty one 14C dates. The older (deeper) parts of both of the LSU Campus Mounds contain many thin, burned ash lenses, suggesting that the Mounds may have been used for ceremonial or cremation purposes. These ash layers are composed mainly of phytoliths, bio-silicate (SiO2) structural compounds in plants that remained after burning of these plants. Analysis of the …

Comparison Of Microstructure And Tensile Behavior Of Hydroxyapatite-Coated Peek Meshes And Cellulose-Based Fabrics And Mats, Armaghan Naderi, Genevieve Palardy

Faculty Publications

Polymeric biomaterials, such as polyether ether ketone (PEEK) and cellulose, have been explored as scaffolds for bone tissue engineering in the past decade. In this study, microstructure and mechanical behavior of uncoated and hydroxyapatite (HA)-coated polymeric meshes, fabrics, and mats were investigated. Commercially available monofilament PEEK meshes, and cellulose fabrics and mats were selected, then coated with a customized low temperature sol–gel method (≤ 150°C). Adhesive HA coating consisting of HA, β-TCP, and CaO with nanorod structure was derived. After HA coating, porosity of substrates (except filter-paper cellulose mats) decreased by up to 43%, indicating effective coating. Both uncoated and …

Verbal Inhibition Declines Among Older Women With High Fmr1 Premutation Expansions: A Prospective Study, Nell Maltman, Leann Dawalt, Jinkuk Hong, Audra Sterling, Elizabeth Berry-Kravis, Jessica Klusek, Marsha R. Mailick

Faculty Publications

The FMR1 premutation has been associated with difficulties in executive functioning, including verbal inhibition. However, little is known about the longitudinal profiles of verbal inhibition among FMR1 premutation carriers, particularly in women, and how individual factors such as aging and CGG repeat length may contribute to changes in verbal inhibition over time. The present study examined verbal inhibition performance (i.e., inhibition errors) on the Hayling Sentence Completion Task in a cohort of 92 women with the FMR1 premutation across two timepoints approximately three years apart. We examined the effects of age, CGG repeat length, and their interactions on verbal inhibition …

Treatment Pearls: Management Of Physical Healthcare Needs In Patients With Mental Illness, Leslie W. Miles, Brandon Thatcher, Michael C. Thomas, Blaine Winters

Faculty Publications

Clinicians caring for persons with mental illness should be aware of increased mortality, physical problems, and health disparities in this population. This article provides a brief overview of physical health problems in the context of mental illness as well as those related to psychotropic medications, and discusses strategies to manage treatment effectively.

Flowunsteady: An Interactional Aerodynamics Solver For Multirotor Aircraft And Wind Energy, Eduardo Alvarez, Judd Mehr, Andrew Ning

Faculty Publications

The ability to accurately and rapidly assess unsteady interactional aerodynamics is a shortcoming and bottleneck in the design of various next-generation aerospace systems: from electric vertical takeoff and landing (eVTOL) aircraft to airborne wind energy (AWE) and wind farms. In this study, we present a meshless CFD framework based on the reformulated vortex particle method (rVPM) for the analysis of complex interactional aerodynamics. The rVPM is a large eddy simulation (LES) solving the Navier-Stokes equations in their vorticity form. It uses a meshless Lagrangian scheme, which not only avoids the hurdles of mesh generation, but it also conserves the vortical …

Smith's Last Stand? Free Exercise And Foster Care Exceptionalism, James G. Dwyer

Faculty Publications

Part I first situates Fulton [Fulton v. City of Philadelphia] within two broader contexts—the clash between social equality rights for sexual minorities and religious freedom, and a pattern of eliding children from legal contests over their lives. It then explains why the standard constitutional framing of social equality versus religious freedom contests is improper when the state is acting as guardian and proxy for children or other non-autonomous persons. Part II sets out a proper framework for analyzing these conflicts, elucidating the scope and nature of the state’s parens patriae authority—a lacuna in constitutional jurisprudence. Part III applies …

Unrestricted Factor Analysis: A Powerful Alternative To Confirmatory Factor Analysis, Jan-Benedict E.M. Steenkamp, Alberto Maydeu-Olivares

Faculty Publications

The gold standard for modeling multiple indicator measurement data is confirmatory factor analysis (CFA), which has many statistical advantages over traditional exploratory factor analysis (EFA). In most CFA applications, items are assumed to be pure indicators of the construct they intend to measure. However, despite our best efforts, this is often not the case. Cross-loadings incorrectly set to zero can only be expressed through the correlations between the factors, leading to biased factor correlations and to biased structural (regression) parameter estimates. This article introduces a third approach, which has emerged in the psychometric literature, viz., unrestricted factor analysis (UFA). UFA …

In Their Own Words: Perspectives On Collection Weeding From Library Employees And Teaching Faculty, Dan Broadbent, Megan Frost, Gregory M. Nelson, David Pixton

Faculty Publications

Following a Science and Engineering collection weeding project of over 350,000 print items, our research team conducted interviews with 20 library employees and 19 teaching faculty involved in the project. The purpose of the interviews was to assess the interviewees’ perspectives and feelings relating to the time required to complete the project, inter- and intra- library communication, the decision-making processes, and their personal assessment of the costs and benefits of the project. The interviewees also offered their views of the overall project’s successes and areas for improvement. Drawing from a qualitative analysis of the interviews, we provide guidance for other …

Trauma And Poetry. The Case Of Primo Levi, Ilona Klein

Faculty Publications

Most North American readers have come to know and appreciate Primo Levi by his major works in prose. His The Periodic Table (1984) catapulted Levi onto the American stage of scientific-humanistic authors, having the New York Times named it among the Best Books of the Year in 1985. Instead, American readers will likely stumble upon Levi’s poetry by accident, simply because every now and then one of his poems in translation appears in print somewhere. Compared to Levi’s prose, his poems inevitably evoke a sense of unease, for their tone, their style and their content are so unlike the familiar, …

Reducing Administrative Burdens To Protect Taxpayer Rights, Leslie Book, T. Keith Fogg, Nina E. Olson

Faculty Publications

The tax system designed by Congress imposes significant administrative burdens on taxpayers. IRS decisions regarding how it administers tax laws can add to congressionally imposed burdens. The administrative burdens are consequential and hurt some people, especially lower- or moderate- income individual taxpayers, more than others. While the IRS strives to measure and reduce the time and money taxpayers spend to comply with their tax obligations, it does not consider the effect administrative burdens have on taxpayer rights, including the right to be informed, the right to pay no more than the correct amount of tax, and the right to a …

Nature Versus Humans In Coastal Environmental Change: Assessing The Impacts Of Hurricanes Zeta And Ida In The Context Of Beach Nourishment Projects In The Mississippi River Delta, Qiang Yao, Marcelo Cancela Lisboa Cohen, Kam-Biu Liu, Adriana Vivan De Souza, Erika Rodrigues

Faculty Publications

No abstract provided.

The Reproductive Biology Of Small Fishes And The Clutch Concept: Combining Macroscopic And Histological Approaches, David C. Heins, Nancy J. Brown-Peterson

Faculty Publications

Accurate estimates of reproductive parameters important in understanding life history evolution and conservation of small fishes are dependent upon careful assignment of ovarian phases. Proper assignment is based upon the stages of propagule (oocyte) development, oocyte maturation and the location of any clutch or portion thereof within the ovaries. Macroscopic inspection and assignment of ovarian developmental phases have often been used for small freshwater fishes. By contrast, histological methods for assignment of reproductive phases have been developed and are widely used for marine fishes, but they have rarely been used for small freshwater fishes. We review oocyte development, ovum maturation, …

Electroanalytical Measurements Of Lanthanum (Iii) Chloride In Molten Calcium Chloride And Molten Calcium Chloride And Lithium Chloride, Mark H. Schvaneveldt, Ranon Fuller, Devin Rappleye

Faculty Publications

Cyclic voltammetry (CV), square wave voltammetry (SWV) and other electroanalytical methods have been applied to molten chloride salts to study metal ion behavior. These studies have been useful for understanding and optimizing the electrowinning of metals. Notable ions that have been studied are rare earth and actinide metal ions in LiCl-KCl salts. However, the behavior of lanthanum (La³⁺) ions in some molten chlorides or chloride mixtures (e.g., CaCl₂) has not been studied. CV experiments were conducted to evaluate La³⁺ behavior in CaCl₂-LiCl and CaCl₂ and were compared to La³⁺ behavior in …

Semantic Segmentation To Extract Coronary Arteries In Invasive Coronary Angiograms, Chen Zhao, Robert Bober, Haipeng Tang, Jinshan Tang, Minghao Dong, Chaoyang Zhang, Zhuo He, Michele L. Esposito, Zhihiu Xu, Weihua Zhou

Faculty Publications

Accurate semantic segmentation of each coronary artery using invasive coronary angiography (ICA) is important for stenosis assessment and coronary artery disease (CAD) diagnosis. In this paper, we propose a multi-step semantic segmentation algorithm based on analyzing arterial sements extraced from ICAs. The proposed algorithm firstly extracts the entire arterial binary mask (binary vascular tree) using a deep learning-based method. Then we extract the centerline of the binary vascular tree and separate it into different arterial segments. Finally, by extracting the underlyingarterial topology, position, and pixel features, we construct a powerful coronary artery segment classifier based on a support vector machine. …

Soil Salinity Estimation Over Coastal Wetlands Based On Random Forest Algorithm And Hydrological Connectivity Metric, Haochen Sui, Dawei Chen, Jiaguo Yan, Bin Li, Wei Li, Baoshan Cui

Faculty Publications

Owing to climate warming and human activities (irrigation and reservoirs), sea level rise and runoff reduction have been threatening the coastal ecosystem by increasing the soil salinity. However, short-term sparse in situ observations limit the study on the response of coastal soil salinity to external stressors and thus its effect on coastal ecosystem. In this study, based on hydrological connectivity metric and random forest algorithm (RF), we develop a coastal soil salinity inversion model with in situ observations and satellite-based datasets. Using Landsat images and ancillary as input variables, we produce a 30-m monthly grid dataset of surface soil salinity …

Improved Limit On Tensor Currents In The Weak Interaction From Li 8 Β Decay, M. T. Burkey, G. Savard, A. T. Gallant, N. D. Scielzo, J. A. Clark, T. Y. Hirsh, L. Varriano, G. H. Sargsyan, K. D. Launey, M. Brodeur, D. P. Burdette, E. Heckmaier, K. Joerres, J. W. Klimes, K. Kolos, A. Laminack, K. G. Leach, A. F. Levand, B. Longfellow, B. Maaß, S. T. Marley, G. E. Morgan, P. Mueller, R. Orford, S. W. Padgett, A. Pérez Galván, J. R. Pierce, D. Ray, R. Segel, K. Siegl, K. S. Sharma, B. S. Wang

Faculty Publications

The electroweak interaction in the standard model is described by a pure vector-axial-vector structure, though any Lorentz-invariant component could contribute. In this Letter, we present the most precise measurement of tensor currents in the low-energy regime by examining the β-ν¯ correlation of trapped Li8 ions with the Beta-decay Paul Trap. We find aβν=-0.3325±0.0013stat±0.0019syst at 1σ for the case of coupling to right-handed neutrinos (CT=-CT′), which is consistent with the standard model prediction.