Digital Commons Network^™

Embryonic Exposure To The Benzotriazole Ultraviolet Stabilizer 2-(2h-Benzotriazol-2-Yl)-4-Methylphenol Decreases Fertility Of Adult Zebrafish (Danio Rerio), Yamin Raza, Emily Mertens, Lauren Zink, Zhe Lu, Jon A. Doering, Steve Wiseman

Faculty Publications

Benzotriazole ultraviolet stabilizers (BUVSs) are emerging contaminants of concern. They are added to a variety of products, including building materials, personal care products, paints, and plastics, to prevent degradation caused by ultraviolet (UV) light. Despite widespread occurrence in aquatic environments, little is known regarding the effects of BUVSs on aquatic organisms. The aim of the present study was to characterize the effects of exposure to 2-(2H-benzotriazol-2-yl)-4-methylphenol (UV-P) on the reproductive success of zebrafish (Danio rerio) following embryonic exposure. Embryos were exposed, by use of microinjection, to UV-P at < 1.5 (control), 2.77, and 24.25 ng/g egg, and reared until sexual maturity, when reproductive performance was assessed, following which molecular and biochemical endpoints were analyzed. Exposure to UV-P did not have a significant effect on fecundity. However, there was a significant effect on fertilization success. Using UV-P-exposed males and females, fertility was decreased by 8.75% in the low treatment group and by 15.02% in the high treatment group relative to control. In a reproduction assay with UV-P-exposed males and control females, fertility was decreased by 11.47% in the high treatment group relative to the control. Embryonic exposure to UV-P might have perturbed male sex steroid synthesis as indicated by small changes in blood plasma concentrations of 17β-estradiol and 11-ketotestosterone, and small statistically nonsignificant decreases in mRNA abundances of cyp19a1a, cyp11c1, and hsd17b3. In addition, decreased transcript abundances of genes involved in spermatogenesis, such as nanos2 and dazl, were observed. Decreases in later stages of sperm development were observed, suggesting that embryonic exposure to UV-P impaired spematogenesis, resulting in decreased sperm quantity. The present study is the first to demonstrate latent effects of BUVSs, specifically on fish reproduction. Environ Toxicol Chem 2024;43:385–397. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.

Opposing Genetic Patterns Of Range Shifting Temperate And Tropical Gastropods In An Area Undergoing Tropicalisation, Karolina M. Zarzyczny, Michael E. Hellberg, Elena B. Lugli, Moira Maclean, David A. Paz-García, Marc Rius, Ethan G. Ross, Erick X. Treviño Balandra, James Vanstone, Suzanne T. Williams, Phillip B. Fenberg

Faculty Publications

Aim: The poleward range expansion of tropical species, and range contraction of temperate species (known as tropicalisation) has mainly been studied from an ecological perspective, with little research on its genetic consequences. Here, we used distributional and genetic data to document the consequences of tropicalisation in rocky shore gastropods and assess more broadly the future implications of tropicalisation on phylogeographic patterns. Location: Nineteen sampling sites along >3000 km of the eastern Pacific rocky intertidal zone, from the tip of the Baja California Peninsula to southern California. Taxon: Temperate gastropods: Lottia conus, L. strigatella, Fissurella volcano and Tegula gallina. Tropical gastropods: …

Simultaneous Detection And Quantification Of Multiple Pathogen Targets In Wastewater, Gouthami Rao, Drew Capone, Kevin Zhu, Abigail Knoble, Yarrow Linden, Ryan Clark, Amanda Lai, Juhee Kim, Ching Hua Huang, Aaron Bivins, Joe Brown

Faculty Publications

Wastewater-based epidemiology has emerged as a critical tool for public health surveillance, building on decades of environmental surveillance work for pathogens such as poliovirus. Work to date has been limited to monitoring a single pathogen or small numbers of pathogens in targeted studies; however, few studies consider simultaneous quantitative analysis of a wide variety of pathogens, which could greatly increase the utility of wastewater surveillance. We developed a novel quantitative multi-pathogen surveillance approach (35 pathogen targets including bacteria, viruses, protozoa, and helminths) using TaqMan Array Cards (TAC) and applied the method on concentrated wastewater samples collected at four wastewater treatment …

Energy And Spectrum Efficient Federated Learning Via High-Precision Over-The-Air Computation, Liang Li, Chenpei Huang, Dian Shi, Hao Wang, Xiangwei Zhou, Minglei Shu, Miao Pan

Faculty Publications

Federated learning (FL) enables mobile devices to collaboratively learn a shared prediction model while keeping data locally. However, there are two major research challenges to practically deploy FL over mobile devices: (i) frequent wireless updates of huge size gradients v.s. limited spectrum resources, and (ii) energy-hungry FL communication and local computing during training v.s. battery-constrained mobile devices. To address those challenges, in this paper, we propose a novel multi-bit over-the-air computation (M-AirComp) approach for spectrum-efficient aggregation of local model updates in FL and further present an energy-efficient FL design for mobile devices. Specifically, a high-precision digital modulation scheme is designed …

Global Change Impacts On Indigenous Sustainability In Sakha Republic: A Synthesis Of Knowledge, Stanislav Saas Ksenofontov, Andrey N. Petrov

Faculty Publications

Indigenous understanding of sustainability is embedded in close relations to land and environment, Indigenous Knowledge systems, Indigenous epistemologies and ontologies, and Indigenous languages. However, the sustainability of Indigenous peoples’ livelihoods is significantly affected by various global change drivers. In the Arctic, Indigenous peoples’ livelihoods are impacted by environmental, social, and cultural changes, including climate change, environmental pollution, economic processes, and resource extraction. This paper aims to review and synthesize recent academic and gray literature on the sustainability of Indigenous communities in Sakha Republic, Northeast Siberia, Russia in the face of global change with a particular focus on land- and water-based …

A Codified Liabilty Regime To Stimulate Greater Investment In Subpatentable Innovation, Ana Santos Rutschman, Jerome H. Reichman

Faculty Publications

The global intellectual property system rests on a distinction between exclusive property rights and free competition. Exclusive rights vary in strength and intensity, but the opposite of protection is almost always free competition. Distinctions of intensity are drawn in terms of the length of protection given to different subject matters plus variable lists of exceptions and limitations to exclusive rights. But the bottom line is that, when protection is not available under the existing system, free competition prevails, and vice-versa (i.e., where there is exclusivity, free competition is deferred for a specified period of time).

This Article departs from a …

Sovereignty And Dependence In The American Empire: Native Nations, Territories, And Overseas Colonies, Alvin Padilla-Babilonia

Faculty Publications

What justifies plenary powers over Native nations, U.S. territories, and overseas colonies? One answer is the text of the Constitution: the Indian Commerce Clause or the Territorial Clause. Another answer is sovereignty under international law. In this Article, I argue that these legalistic explanations overlook a third answer: that political and judicial actors justified plenary powers based on the colonial notion that these so-called dependent peoples were incapable of self- government.

Members of Congress, presidents, federal judges, and territorial governors reconciled republicanism and colonialism in the American empire by constituting Native nations, the territories, and the overseas colonies as dependent …

Ears To Hear: How To Study The Bible And Let Scripture Speak For Itself, Félix H. Cortez

Faculty Publications

No abstract provided.

The Nitrogen Footprint Of Ukraine: Why Personal Consumption Matters, Sergiy Medinets, Allison M. Leach, Tetiana Pavlik, Volodymyr Medinets, James N. Galloway

Faculty Publications

Unintended reactive nitrogen (N) losses from agriculture, energy and transportation pose significant environmental hazards, including eutrophication, acidification, water and air pollution, biodiversity loss, human health risks and climate change. The concept of a nitrogen footprint (NF) emerges as a pivotal metric, reflecting potential N losses in the entire production-consumption chain of goods and services used by an individual within a defined timeframe.In a pioneering assessment of per capita NF in Ukraine, key factors, such as the food production chain, consumption patterns, connection to wastewater treatment (WWT) system and the efficacy of WWT facilities, were identified as critical components. Addressing specific …

The Cetacean Sanctuary: A Sea Of Unknowns, Jason N. Bruck

Faculty Publications

Housing cetaceans in netted sea pens is not new and is common for many accredited managed- care facilities. Hence, the distinction between sanctuary and sea pen is more about the philosophies of those who run these sanctuary facilities, the effects of these philosophies on the animals’ welfare, and how proponents of these sanctuaries fund the care of these animals. Here, I consider what plans exist for cetacean sanctuaries and discuss the caveats and challenges associated with this form of activist-managed captivity. One goal for stakeholders should be to disregard the emotional connotations of the word “sanctuary” …

Scaffold-Based 3d Cell Culture Models In Cancer Research, Waad H. Abuwatfa, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. In 3D cell cultures, cancer cells are grown in an environment that more closely mimics the 3D architecture and complexity of in vivo tumors. This approach has revolutionized cancer research by providing a more accurate representation of the tumor microenvironment (TME) and enabling the study of tumor behavior and response to therapies in a more physiologically relevant context. One of the key benefits of 3D cell culture in cancer research is the ability to recapitulate the complex interactions …

Indigenous Peoples And Local Communities Report Ongoing And Widespread Climate Change Impacts On Local Social-Ecological Systems, Victoria Sharakhmatova, Victoria Reyes-García, David García-Del-Amo, Santiago Álvarez-Fernández, Petra Benyei, Laura Calvet-Mir, André B. Junqueira, Vanesse Labeyrie, Xiaoyue Li, Sara Miñarro, Vincent Porcher, Anna Porcuna-Ferrer, Anna Schlingmann, Christoph Schunko, Ramin Soleymani, Adrien Tofighi-Niaki, Mariam Abazeri, Emmanuel M.N.A.N. Attoh, Ayansina Ayanlade, Julia Vieira Da Cunha Ávila, Daniel Babai, Rodrigo C. Bulamah, Joao Campos-Silva, Rosario Carmona, Julián Caviedes, Rumbidzayi Chakauya, Mouna Chambon, Zhuo Chen, Fasco Chengula, Esther Conde, Aida Cuní-Sanchez

Faculty Publications

The effects of climate change depend on specific local circumstances, posing a challenge for worldwide research to comprehensively encompass the diverse impacts on various local social-ecological systems. Here we use a place-specific but cross-culturally comparable protocol to document climate change indicators and impacts as locally experienced and analyze their distribution. We collected first-hand data in 48 sites inhabited by Indigenous Peoples and local communities and covering all climate zones and nature-dependent livelihoods. We documented 1,661 site-agreed reports of change corresponding to 369 indicators. Reports of change vary according to climate zone and livelihood activity. We provide compelling evidence that climate …

Analyzing Water Resource Challenges In The Us Eastern Zone, Yaw Twumasi, E. C. Merem, S. Fageir, D. Olagbegi, J. Wesley, R. Coney, Y. Babalola, T. Thomas, A. Hines, G. Hirse, G. S. Ochai, E. Nwagboso, M. Crisler, S. Leggett, J. Offiah, S. Emeakpor

Faculty Publications

One major narrative over the last several years, consistent with the US Northeast region in policy discourse rests on its perception as a hub with high concentration of city bright lights and skyscrapers but short on water usage. In the process, no one thinks about how the rising demands from urban residential areas to hydroelectricity and climate change stressors impact the hydrology. Yet, what is forgotten is that the economic engine driving the region comes from the interactions in a complex hydrological network anchored in water distribution dependency. At the same time, a closer look at various states indicates that …

The Effects Of Changing Climate In The Us Western Region, Yaw Twumasi, E. C. Merem, Y. A. Twumasi, S. Fageir, D. Olagbegi, J. Wesley, R. Coney, Y. Babalola, T. Thomas, A. Hines, G. Hirse, G. S. Ochai, E. Nwagboso, M. Crisler, S. Leggett, J. Offiah, S. Emeakpor

Faculty Publications

he Pacific Northwest region of the US has over the years, outpaced other zones in the country in every socio-economic indicator. Known for its enviable physical attributes of high montane ecosystem and warm weather all year round in some places together with abundant biodiversity. The region’s position as among the fastest growing areas in the nation under vast swaths of land with large population concentration in big cities has made it the perennial destination for many. Aside from all these, in the last several years, the zone continues to be the epicenter of the most dangerous natural disasters prompted by …

Analyzing The Capacities Of Cotton Production In Sudan, Yaw Twumasi, E. C. Merem, S. Fageir, D. Olagbegi, J. Wesley, R. Coney, Y. Babalola, T. Thomas, A. Hines, G. Hirse, G. S. Ochai, E. Nwagboso, M. Crisler, E. Nwagboso, M. Crisler, S. Leggett, J. Offiah, S. Emeakpor

Faculty Publications

In the political economy of the nation of Sudan, cotton ranks significantly high as an essential component of the revenue generation sources. Considering the significance of the crop in the country, cotton has not only been exported to various countries, but some portions of the produce are also used up internally. With that also came, large scale cultivation of the cotton produce on vast swaths of land over the years amidst demands and fluctuations in the marketplace. Given the effects of cotton production on the environment from the use of chemicals and widespread water use, there came changes in the …

Exploring Shifts In Yam Production Trends Along Nigeria’S Southern Region, Yaw Twumasi, E. C. Merem, S. Fageir, D. Olagbegi, J. Wesley, R. Coney, Y. Babalola, T. Thomas, A. Hines, G. Hirse, G. S. Ochai, E. Nwagboso, M. Crisler, S. Leggett, J. Offiah, S. Emeakpor

Faculty Publications

Yam as a staple commodity in Nigeria, remains generally grown in different places within the ecological zones and food hubs in the nation. Notwithstanding all that, being integral part of the nation’s food security in a setting where Nigeria ranks high as the largest producer globally. Still, yam continues to find ample use with essential role for numerous purposes. Classified as an important food crop, the use of yam runs deeper, given its high demands for religious, socio-cultural practices, the economy, industries, and the marketplace. Even at that and considering the vast presence of yams over large swaths of land …

Creative Reading: Using Poetic Inquiry In Research And Teaching, Clancy Ratliff, Abdullah Al Musayeb, Barja Islam, Mithila Mumtaz, Rosol Otear, Simon Richard, Noah Smith, Nuzhat Tarannum, Allyssa Veney

Faculty Publications

No abstract provided.

Habitat Use And Movements Of Parrotfishes In A Hawaiian Coral Reef Seascape, Senifa F. Annandale, Jason P. Turner, Daniel L. Lippi, Michael Dance, R. J.David Wells, Jay R. Rooker

Faculty Publications

Parrotfishes (family Scaridae) are important to coral reef ecosystems and highly prized by both commercial and recreational fishers in the Hawaiian Islands. Although parrotfishes are known to be strictly diurnal, our knowledge of their habitat use and movement patterns across daily timescales in tropical systems is still somewhat limited. Here, acoustic telemetry was used to determine parrotfish habitat use and movements within a coral reef seascape at Puakō, Hawai‘i. An array of acoustic receivers was deployed in a nearshore reef to track fine-scale movements of two common species: ember parrotfish (Scarus rubroviolaceus) and palenose parrotfish (Scarus psittacus). Transmitters were mounted …

Seaweed As A Resilient Food Solution After A Nuclear War, Florian Ulrich Jehn, Farrah Jasmine Dingal, Aron Mill, Cheryl Harrison, Ekaterina Ilin, Michael Y. Roleda, Scott C. James, David Denkenberger

Faculty Publications

Abrupt sunlight reduction scenarios such as a nuclear winter caused by the burning of cities in a nuclear war, an asteroid/comet impact or an eruption of a large volcano inject large amounts of particles in the atmosphere, which limit sunlight. This could decimate agriculture as it is practiced today. We therefore need resilient food sources for such an event. One promising candidate is seaweed, as it can grow quickly in a wide range of environmental conditions. To explore the feasibility of seaweed after nuclear war, we simulate the growth of seaweed on a global scale using an empirical model based …

Killing Stays, Madalyn K. Wasilczuk

Faculty Publications

For decades, the Supreme Court has been suspicious of litigation under warrant in capital cases. The Court has described last-minute litigation as manipulative and dilatory, a result of gamesmanship by people on death row and their lawyers. With the confirmation of Justice Brett Kavanaugh in 2018, the Court began to extinguish the opportunity to assert death row detainees’ rights against unlawful death sentences and executions, reaching a crescendo of stay vacaturs and denials during the Trump executions. Despite this sea change in capital stay jurisprudence and practice, few scholars have focused on the capital stay as a vital component of …

Mir-379-5p Affects Breast Cancer Cell Behavior By Targeting Ube2e3 Ubiquitin Conjugating Enzyme, Araya K. Schroder, Conor J. Loy, Fernanda Aiala, Jazmyn Rafique, Arnob Ghosh, Lina I. Yoo

Faculty Publications

No abstract provided.

Common Questions And Misconceptions About Caffeine Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Daniel E. Newmire, Jeffrey R. Stout, Brandi Antonio, Maureen Gibbons, Lonnie M. Lowery, Joseph Harper, Darryn Willoughby, Cassandra Evans, Dawn Anderson, Erica Goldstein, Jose Rojas, Matías Monsalves-Álvarez, Scott C. Forbes, Jose Gomez Lopez, Tim Ziegenfuss, Blake D. Moulding, Darren Candow, Michael Sagner, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak

Faculty Publications

Caffeine is a popular ergogenic aid that has a plethora of evidence highlighting its positive effects. A Google Scholar search using the keywords “caffeine” and “exercise” yields over 200,000 results, emphasizing the extensive research on this topic. However, despite the vast amount of available data, it is intriguing that uncertainties persist regarding the effectiveness and safety of caffeine. These include but are not limited to: 1. Does caffeine dehydrate you at rest? 2. Does caffeine dehydrate you during exercise? 3. Does caffeine promote the loss of body fat? 4. Does habitual caffeine consumption influence the performance response to acute caffeine …

The Trial Of The Jurors - A Commentary On 12 Angry Men, Jonathan Van Patten

Faculty Publications

The movie, 12 Angry Men, is a fictionalized portrayal of a deliberation in a murder case from inside the jury room.  It provides a memorable treatment of the difficulty of deciding a case solely on the evidence admitted, as well as illuminating the dynamics of argument, emotion, and persuasion, particularly where deep-seated passions preclude honest evaluation of the evidence.

Spatiotemporal Patterns For Agroforestry Tree Crops In The U.S. Corn Belt For Usda Census Of Agriculture Periods 2012–2022, Andria Caruthers, Justin Dijak, Robin M. Rotman

Faculty Publications

Within the U.S., there is a growing need to integrate environmentally friendly practices into conventional agriculture. Agroforestry enhances environmental and resource stewardship in agricultural landscapes while offering potential economic benefits to farmers. Despite rising interest, limited information on its application in the U.S. hinders development efforts. A spatiotemporal analysis of current farm operations can provide crucial insights. This study examined patterns of agroforestry and tree crop adoption in the U.S. Corn Belt using USDA Census data (2012, 2017, and 2022) and spatial tools (Global Moran’s I, Local Moran’s I, and Moran scatterplots). The tree crops included in the analysis were …

News And Perspectives: Words Matter In Primatology, Michelle Bezanson, Liliana Cortés-Ortiz, Júlio César Bicca-Marques, Ramesh Boonratana, Susana Carvalho, Marina Cords, Stella De La Torre, Catherine Hobaiter, Tatyana Humle, Patrícia Izar, Jessica W. Lynch, Tetsuro Matsuzawa, Joanna M. Setchell, Gladys Kalema Zikusoka, Karen B. Strier

Faculty Publications

Postings on social media on Twitter (now X), BioAnthropology News (Facebook), and other venues, as well as recent publications in prominent journals, show that primatologists, ecologists, and other researchers are questioning the terms “Old World” and “New World” due to their colonial implications and history. The terms are offensive if they result in erasing Indigenous voices and history, ignoring the fact that Indigenous peoples were in the Americas long before European colonization. Language use is not without context, but alternative terminology is not always obvious and available. In this perspective, we share opinions expressed by an international group of primatologists …

Serine Proteinase Inhibitors From Nicotiana Benthamiana, A Nonpreferred Host Plant, Inhibit The Growth Of Myzus Persicae (Green Peach Aphid), Honglin Feng, Georg Jander

Faculty Publications

BACKGROUND: The green peach aphid (Myzus persicae) is a severe agricultural crop pest that has developed resistance to most current control methods, requiring the urgent development of novel strategies. Plant proteinase inhibitors (PINs) are small proteins that protect plants against pathogens and/or herbivores, likely by preventing efficient protein digestion. RESULTS: We identified 67 protease genes in the transcriptomes of three M. persicae lineages (USDA-Red, G002 and G006). Comparison of gene expression levels in aphid guts and whole aphids showed that several proteases, including a highly expressed serine protease, are significantly overexpressed in the guts. Furthermore, we identified three genes encoding …

Establishment Of A Practical Sperm Cryopreservation Pathway For The Axolotl (Ambystoma Mexicanum): A Community-Level Approach To Germplasm Repository Development, Nicholas Coxe, Yue Liu, Lucía Arregui, Rose Upton, Sarah Bodenstein, Steven Randal Voss, Maria T. Gutierrez-Wing, Terrence R. Tiersch

Faculty Publications

The axolotl (Ambystoma mexicanum) draws great attention around the world for its importance as a biomedical research model, but housing and maintaining live animals is increasingly expensive and risky as new transgenic lines are developed. The goal of this work was to develop an initial practical pathway for sperm cryopreservation to support germplasm repository development. The present study assembled a pathway through the investigation of axolotl sperm collection by stripping, refrigerated storage in various osmotic pressures, cryopreservation in various cryoprotectants, and in vitro fertilization using thawed sperm. By the stripping of males, 25–800 µL of sperm fluid was collected at …

Covid-19 As A Chronic Stressor And The Importance Of Individual Identity: A Data-Driven Look At Academic Productivity During The Pandemic, Breanna N. Harris, Carolyn M. Bauer, James A. Carr, Caitlin R. Gabor, Jennifer L. Grindstaff, Caleigh Guoynes, Jennifer J. Heppner, Cris C. Ledon-Rettig, Patricia C. Lopes, Sharon E. Lynn, Carla B. Madelaire, Lorin A. Neuman-Lee, Maria G. Palacios, Paul Soto, Jennifer Terry

Faculty Publications

The COVID-19 pandemic impacted personal and professional life. For academics, research, teaching, and service tasks were upended and we all had to navigate the altered landscape. However, some individuals faced a disproportionate burden, particularly academics with minoritized identities or those who were early career, were caregivers, or had intersecting identities. As comparative endocrinologists, we determine how aspects of individual and species-level variation influence response to, recovery from, and resilience in the face of stressors. Here, we flip that framework and apply an integrative biological lens to the impact of the COVID-19 chronic stressor on our endocrine community. We address how …

Alcohol And Cannabis Dual Use Among Black Adults: Associations With Alcohol Use, Use-Related Problems, And Race-Based Discrimination, Julia D. Buckner, Michael J. Zvolensky, Caroline R. Scherzer

Faculty Publications

Background and Objectives: Black adults who drink alcohol appear at risk for poor alcohol-related outcomes, yet little research has examined whether cannabis use among those who consume alcohol (alcohol-cannabis dual use) is related to worse alcohol-related consequences, as observed in predominantly White samples. Further, it may be that experiencing more race-based discrimination may be related to using multiple substances to cope with such experiences; however, no known studies have examined the impact of race-based discrimination on alcohol-cannabis dual use. Methods: Participants were 270 Black undergraduates who endorsed past-month drinking, 112 of whom endorsed alcohol-cannabis dual use. Results: The dual use …

Strategic Environmental Consumer Segmentation: An Exploratory Case Study In Slovakia, Hana Maťová, Miroslava Oravcová Triznová, Vladislav Kaputa, Erika Loučanová, Richard P. Vlosky

Faculty Publications

The desire to live in a healthy “green” environment is becoming increasingly important to global populations. The term “green” is overused, confusing, and inconsistently used among and between consumers, corporate enterprises, environmental groups, government entities, and other segments globally. Research studies suggest that defining and applying the term “green” to behaviors and decision-making is constantly changing, further complicating the study of corporate and consumer environmental responsibility. In this study, we focus on the consumer. Not all consumers behave the same or have the same beliefs and perceptions regarding what is environmentally “green.” As such, we segmented consumers in Slovakia into …