Digital Commons Network^™

Stable Isotope Analyses Of Feather Amino Acids Identify Penguin Migration Strategies At Ocean Basin Scales, Michael J. Polito, Jefferson T. Hinke, Tom Hart, Mercedes Santos, Leah A. Houghton, Simon R. Thorrold

Faculty Publications

No abstract provided.

Simplex Solutions For Optimal Control Flight Paths In Urban Environments, Michael D. Zollars, Richard G. Cobb, David J. Grymin

Faculty Publications

This paper identifies feasible fight paths for Small Unmanned Aircraft Systems in a highly constrained environment. Optimal control software has long been used for vehicle path planning and has proven most successful when an adequate initial guess is presented flight to an optimal control solver. Leveraging fast geometric planning techniques, a large search space is discretized into a set of simplexes where a Dubins path solution is generated and contained in a polygonal search corridor free of path constraints. Direct optimal control methods are then used to determine the optimal flight path through the newly defined search corridor. Two scenarios …

Estimating Parasite Host Range, Tad Dallas, Shan Huang, Charles Nunn, Andrew W. Park, John M. Drake

Faculty Publications

© 2017 The Author(s) Published by the Royal Society. All rights reserved. Estimating the number of host species that a parasite can infect (i.e. host range) provides key insights into the evolution of host specialism and is a central concept in disease ecology. Host range is rarely estimated in real systems, however, because variation in species relative abundance and the detection of rare species makes it challenging to confidently estimate host range. We applied a non-parametric richness indicator to estimate host range in simulated and empirical data, allowing us to assess the influence of sampling heterogeneity and data completeness. After …

International Society Of Sports Nutrition Position Stand: Nutrient Timing, Chad M. Kerksick, Shawn M. Arent, Brad J. Schoenfeld, Jeffrey R. Stout, Bill Campbell, Colin D. Wilborn, Lem Taylor, Doug Kalman, Abbie E. Smith-Ryan, Richard B. Kreider, Darryn Willoughby, Paul J. Arciero, Trisha A. Vandusseldorp, Michael J. Ormsbee, Robert Wildman, Mike Greenwood, Tim N. Ziegenfuss, Alan A. Aragon

Faculty Publications

Position statement

The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained individuals on exercise performance and body composition. The following points summarize the position of the ISSN.

1. Nutrient timing incorporates the use of methodical planning and eating of whole foods, fortified foods and dietary supplements. The timing of energy intake and the ratio of certain ingested macronutrients may enhance recovery and tissue repair, augment muscle protein synthesis (MPS), and improve mood states following high-volume or intense exercise.
2. Endogenous glycogen stores …

Epigenetic Response Of Imprinted Domains During Carcinogenesis, Corey L. Bretz, Ingeborg M. Langohr, Joomyeong Kim

Faculty Publications

© 2017 The Author(s). Background: Imprinted domains have been identified as targets for aberrant DNA methylation during carcinogenesis, but it remains unclear when these epigenetic alterations occur and how they contribute to tumor progression. Epigenetic instability at key cis-regulatory elements within imprinted domains can concomitantly activate proto-oncogenes and turn off tumor suppressor genes. Thus, to further characterize the epigenetic response of imprinted domains during carcinogenesis, we compared the stability of DNA methylation at a variety of cis-regulatory elements within imprinted domains in two fundamentally different mouse tumors, benign and malignant, induced by the KrasG12D mutation. Results: We report that imprinted …

Altered Sensitivity To Social Gaze In The Fmr1 Premutation And Pragmatic Language Competence, Jessica Klusek, Joseph Schmidt, Amanda J. Fairchild, Ann Porter, Jane E. Roberts

Faculty Publications

Background: The FMR1 premutation affects 1:291 women and is associated with a range of cognitive, affective, and physical health complications, including deficits in pragmatic language (i.e., social language). This study investigated attention to eye gaze as a fundamental social-cognitive skill that may be impaired in the FMR1 premutation and could underlie pragmatic deficits. Given the high prevalence of the FMR1 premutation, efforts to define its phenotype and mechanistic underpinnings have significant public health implications. Methods: Thirty-five women with the FMR1 premutation and 20 control women completed an eye-tracking paradigm that recorded time spent dwelling within the eye region in response …

Multiphysics Simulation Of Low-Amplitude Acoustic Wave Detection By Piezoelectric Wafer Active Sensors Validated By In-Situ Ae-Fatigue Experiment, Yeasin Bhuiyan, Victor Giurgiutiu

Faculty Publications

Piezoelectric wafer active sensors (PWAS) are commonly used for detecting Lamb waves for structural health monitoring application. However, in most applications of active sensing, the signals are of high-amplitude and easy to detect. In this article, we have shown a new avenue of using the PWAS transducer for detecting the low-amplitude fatigue-crack related acoustic emission (AE) signals. Multiphysics finite element (FE) simulations were performed with two PWAS transducers bonded to the structure. Various configurations of the sensors were studied by using the simulations. One PWAS was placed near to the fatigue-crack and the other one was placed at a certain …

Response Of East Texas Mid-Rotation Loblolly Pine Plantations To Poultry Litter And Chemical Fertilizer Amendments, Brian P. Oswald, Micah-John Bieirle, Hans M. Williams, Kenneth W. Farrish, I-Kuai Hung

Faculty Publications

No abstract provided.

Reproductive And Metabolic State Differences In Olfactory Responses To Amino Acids In A Mouth Brooding African Cichlid Fish, Alexandre A. Nikonov, Julie M. Butler, Karen E. Field, John Caprio, Karen P. Maruska

Faculty Publications

© 2017. Published by The Company of Biologists Ltd | Journal of Experimental Biology. Olfaction mediates many crucial life-history behaviors such as prey detection, predator avoidance, migration and reproduction. Olfactory function can also be modulated by an animal's internal physiological and metabolic states. While this is relatively well studied in mammals, little is known about how internal state impacts olfaction in fishes, the largest and most diverse group of vertebrates. Here we apply electroolfactograms (EOGs) in the African cichlid fish Astatotilapia burtoni to test the hypothesis that olfactory responses to food-related cues (i.e. L-amino acids; alanine and arginine) vary with …

Temperature-Modulated Expression Of Allometric Respiration Strategies Supports A Metabolic Scaling Rule, Chet F. Rakocinski, Kelsey Burns Gillam

Faculty Publications

A model based on the mass-specific oxygen consumption rate of the tolerant polychaete, Capitella telata, related meaningfully to a novel metabolic scaling rule as applied to the infaunal size spectrum. Depending on temperature, C. telataexpressed divergent oxyregulating or oxyconforming strategies relative to oxygen availability. A non-linear response surface fitted to the allometric exponents of a family of V_O2 curves for 12 treatment combinations of DO saturation and temperature was used to project oxygen consumption rates across the infaunal size spectrum. Plasticity in respiration strategies was evident, based on four simulated dynamic 32 d oxygen-temperature exposure scenarios and …

Alternative Healthy Eating Index 2010, Dietary Inflammatory Index And Risk Of Mortality: Results From The Whitehall Ii Cohort Study And Meta-Analysis Of Previous Dietary Inflammatory Index And Mortality Studies, Nitin Shivappa, James R. Hébert, Mika Kivimaki, Tasnime Akbaraly

Faculty Publications

We aimed to examine the association between the Alternative Healthy Eating Index updated in 2010 (AHEI-2010), the Dietary Inflammatory Index (DIITM) and risk of mortality in the Whitehall II study. We also conducted a meta-analysis on the DII-based results from previous studies to summarise the overall evidence. Data on dietary behaviour assessed by self-administered repeated FFQ and on mortality status were available for 7627 participants from the Whitehall II cohort. Cox proportional hazards regression models were performed to assess the association between cumulative average of AHEI-2010 and DII scores and mortality risk. During 22 years of follow-up, 1001 participants died …

Listeria Occurrence In Poultry Flocks: Detection And Potential Implications, Michael J. Rothrock Jr., Morgan L. Davis, Aude Locatelli, Aaron Bodie, Tori G. Mcintosh, Janet R. Donaldson, Steven C. Ricke

Faculty Publications

Foodborne pathogens such as Salmonella, Campylobacter, Escherichia coli, and Listeria are a major concern within the food industry due to their pathogenic potential to cause infection. Of these, Listeria monocytogenes, possesses a high mortality rate (approximately 20%) and is considered one of the most dangerous foodborne pathogens. Although the usual reservoirs for Listeria transmission have been extensively studied, little is known about the relationship between Listeria and live poultry production. Sporadic and isolated cases of listeriosis have been attributed to poultry production and Listeria spp. have been isolated from all stages of poultry production and processing. Farm studies …

The Relationship Of Plasma Trans Fatty Acids With Dietary Inflammatory Index Among Us Adults, Mohsen Mazidi, Hong-Kai Gao, Nitin Shivappa, Michael David Wirth, James R. Hébert, Andre Pascal Kengne

Faculty Publications

Background: It has been suggested that trans fatty acids (TFAs) play an important role in cardiovascular diseases. We investigated the association between plasma TFAs and the dietary inflammatory index (DII) ™ in US adults.

Methods: National Health and Nutrition Examination Survey (NHANES) participants with data on plasma TFAs measured from 1999 to 2010 were included. Energy-adjusted-DII ™ (E-DII ™) expressed per 1000 kcal was calculated from 24-h dietary recalls. All statistical analyses accounted for the survey design and sample weights.

Results: Of the 5446 eligible participants, 46.8% (n = 2550) were men. The mean age of the population was 47.1 …

Repeated Evolution Of Vertebrate Pollination Syndromes In A Recently Diverged Andean Plant Clade, Laura P. Lagomarsino, Elisabeth J. Forrestel, Nathan Muchhala, Charles C. Davis

Faculty Publications

© 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution. Although specialized interactions, including those involving plants and their pollinators, are often invoked to explain high species diversity, they are rarely explored at macroevolutionary scales. We investigate the dynamic evolution of hummingbird and bat pollination syndromes in the centropogonid clade (Lobelioideae: Campanulaceae), an Andean-centered group of ∼550 angiosperm species. We demonstrate that flowers hypothesized to be adapted to different pollinators based on flower color fall into distinct regions of morphospace, and this is validated by morphology of species with known pollinators. This supports the existence of …

Selection Of Breeding Stock By U.S. Meat Goat Producers, Narayan Nyaupane, Jeffrey Gillespie, Kenneth Mcmillin, Robert Harrison, Isaac Sitienei

Faculty Publications

© 2017 The Author(s). Using nationwide survey data, we investigate U.S. meat goat producer preferences and willingness to pay for meat goat breeding stock attributes. Discrete choice experiments were employed, and mixed logit and latent class models were used for analysis. Results showed that producers preferred animals that were highly masculine/feminine, had good structure and soundness, and were of the Boer breed, whereas they preferred fewer animals that were older, of Kiko and Spanish breeds, and priced higher. Significant preference heterogeneity was found among the respondents. Larger-scale producers had greater preference for high masculinity/femininity, good structure and soundness, and Boer …

Retinoic Acid Inhibits White Adipogenesis By Disrupting Gadd45a-Mediated Zfp423 Dna Demethylation, Bo Wang, Xing Fu, Mei Jun Zhu, Min Du

Faculty Publications

© The Author (2017). Retinoic acid (RA), a bioactive metabolite of Vitamin A, is a critical mediator of cell differentiation. RA blocks adipogenesis, but mechanisms remain to be established. ZFP423 is a key transcription factor maintaining white adipose identity. We found that RA inhibits Zfp423 expression and adipogenesis via blocking DNA demethylation in the promoter of Zfp423, a process mediated by growth arrest and DNA-damage-inducible protein alpha (GADD45A). RA induces the partnering between retinoic acid receptor (RAR) and tumor suppressor inhibitor of growth protein 1 (ING1), which prevents the formation of GADD45A and ING1 complex necessary for locus-specific Zfp423 DNA …

The Faithless Elector And 2016: Constitutional Uncertainty After The Election Of Donald Trump, Alexander Gouzoules

Faculty Publications

Presidential electors are generally expected to vote for the candidate who won their state's election, and those who do not are referred to as "faithless electors." A majority of states have laws of varying types that bind their electors to vote for the winning presidential candidate. The 2016 election, for the first time in modern history, produced a serious movement urging electors to cast faithless votes against Donald Trump. Although this movement was not successful, 2016 saw the most faithless electors in recent history by a large margin. Three separate, ultimately unsuccessful, lawsuits were filed by would-be faithless electors in …

Structural And Mutational Analyses Of The Leptospira Interrogans Virulence-Related Heme Oxygenase Provide Insights Into Its Catalytic Mechanism, Anabel Soldano, Sebastián Klinke, Lisandro H. Otero, Mario Rivera, Daniela L. Catalano-Dupuy, Eduardo A. Ceccarelli

Faculty Publications

© 2017 Soldano et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Heme oxygenase from Leptospira interrogans is an important virulence factor. During catalysis, redox equivalents are provided to this enzyme by the plastidic-type ferredoxin-NADP+ reductase also found in L. interrogans. This process may have evolved to aid this bacterial pathogen to obtain heme-iron from their host and enable successful colonization. Herein we report the crystal structure of the heme oxygenase-heme complex at …

Estradiol Modulates Neural Response To Conspecific And Heterospecific Song In Female House Sparrows: An In Vivo Positron Emission Tomography Study, Christine R. Lattin, Frank A. Stabile, Richard E. Carson

Faculty Publications

© 2017 Lattin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Although there is growing evidence that estradiol modulates female perception of male sexual signals, relatively little research has focused on female auditory processing. We used in vivo 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) imaging to examine the neuronal effects of estradiol and conspecific song in female house sparrows (Passer domesticus). We assessed brain glucose metabolism, a measure of neuronal activity, in …

Economic Growth And Mortality: Do Social Protection Policies Matter?, Usama Bilal, Richard Cooper, Francis Abreu, Claudia Nau, Manuel Franco, Thomas A. Glass

Faculty Publications

Background: In the 20th century, periods of macroeconomic growth have been associated with increases in population mortality. Factors that cause or mitigate this association are not well understood. Evidence suggests that social policy may buffer the deleterious impact of economic growth. We sought to explore associations between changing unemployment (as a proxy for economic change) and trends in mortality over 30 years in the context of varying social protection expenditures. Methods: We model change in all-cause mortality in 21 OECD (Organization for Economic Cooperation and Development) countries from 1980 to 2010. Data from the Comparative Welfare States Data Set and …

Genistein Crosses The Bioartificial Oviduct And Alters Secretion Composition, Constantine A. Simintiras, Roger G. Sturmey

Faculty Publications

The dietary derived isoflavone and oestrogen analogue, genistein, is known to perturb fundamental reproductive events such as implantation and embryo cleavage. However the question of whether genistein is able to traverse the oviduct epithelial monolayer and impact oviduct fluid secretion remains unclear. This study tests these research questions using a bioartificial oviduct to show that genistein permeates the oviduct lumen in vitro with a biphasic (burst and plateau) kinetic profile, faster than spontaneous diffusion, and alters the amino acid composition of in vitro derived oviduct fluid (ivDOF) but not as an oestrogen analogue. In addition to offering insights into the …

Egg Quality Traits And Predictors Of Embryo And Fry Viability In Red Snapper Lutjanus Campechanus, Agnés Bardon-Albaret, Eric Saillant

Faculty Publications

The quality of red snapper eggs is highly variable and unpredictable in aquaculture, leading to high mortality during early larval rearing. In this work, the viability of red snapper eggs was monitored from fertilization until unfed larvae expired because of exhaustion of vitelline reserves to determine egg quality traits in this species. The spawns were obtained via strip spawning wild-caught females following hormonal induction with chorionic gonadotropin. Females were induced immediately after capture (wild group, n = 17) or held captive for the entire maturation period prior to induction (captive group, n = 7). Candidate predictors of egg quality measured …

Oviposition Preference And Offspring Performance In Container Breeding Mosquitoes: Evaluating The Effects Of Organic Compounds And Laboratory Colonisation, David W. Allgood, Donald A. Yee

Faculty Publications

1. The preference–performance hypothesis (PPH) predicts that organisms lacking parental care should oviposit in habitats that optimise offspring performance. Preference–performance relationships were investigated for the Asian tiger mosquito (Aedes albopictus Skuse) and the southern house mosquito (Culex quinquefasciatus Say) (Diptera: Culicidae), two medically important container-breeding species, in response to an organic chemical blend mimicking decaying plant matter. Additionally, the effects of long-term laboratory colonisation of Cx. quinquefasciatus using wild and laboratory strains were evaluated.

2. Oviposition bioassays were conducted by releasing gravid mosquitoes into field enclosures with automobile tires containing low and high concentrations of the chemical blend, …

Catalase Is A Determinant Of The Colonization And Transovarial Transmission Of Rickettsia Parkeri In The Gulf Coast Tick Amblyomma Maculatum, Khemraj Budachetri, Deepak Kumar, Shahid Karim

Faculty Publications

The Gulf Coast tick (Amblyomma maculatum) has evolved as a competent vector of the spotted‐fever group rickettsia, Rickettsia parkeri. In this study, the functional role of catalase, an enzyme responsible for the degradation of toxic hydrogen peroxide, in the colonization of the tick vector by R. parkeri and transovarial transmission of this pathogen to the next tick generation, was investigated. Catalase gene (CAT) expression in midgut, salivary glands and ovarian tissues exhibited a 2–11‐fold increase in transcription level upon R. parkeri infection. Depletion of CAT transcripts using an RNA‐interference approach significantly reduced R. parkeri infection …

Stable Isotopes And Radiocarbon Assess Variable Importance Of Plants And Fungi In Diets Of Arctic Ground Squirrels, Erik A. Hobbie, Julee Shamhart, Michael Sheriff, Andrew P. Ouimette, Matt Trappe, Edward A. G. Schuur, John E. Hobbie, Rudy Boonstra, Brian M. Barnes

Faculty Publications

Arctic ground squirrels (Urocitellus parryii) rely primarily on dietary protein derived from plants to fuel gluconeogenesis during hibernation, yet fungal sporocarps may be an important, yet overlooked, protein source. Fungivory levels depend on sporocarp productivity, which varies with the dominant plant species and is higher on acidic than on non-acidic soils. To test whether these factors altered fungal consumption, we used stable isotopes to investigate arctic ground squirrel diets at two sites in northern Alaska, Toolik (primarily moist acidic tundra) and Atigun (primarily moist non-acidic tundra). Radiocarbon estimates can also indicate fungivory levels because ectomycorrhizal fungi assimilate soil-derived organic nitrogen …

Branding India: Constructing A Reputation For Responsibility In The Nuclear Order, Karthika Sasikumar

Faculty Publications

Nation-branding professionals have the same goal as diplomats and politicians – the goal of endowing the nation with specific qualities in the minds of the target audience, so that it is identified with those qualities. In other words, they are constructing an identity for the country. Insights from the commercial practice of nation branding can illuminate the process of identity construction by states. As an illustration, the paper investigates the case of India’s branding/self-presentation as a responsible holder of nuclear weapons. In 1998, India declared itself a Nuclear Weapon State (NWS). Since India has not been granted NWS status under …

Mass Communication Law And Policy Research And The Values Of Free Expression, Edward L. Carter

Faculty Publications

Mass communication law and policy research, including on values and theory of freedom of expression, has played an important role in Journalism & Mass Communication Quarterly for decades. Mass communication law research in Quarterly reached a high point with a special issue on the First Amendment in 1992 and numerous articles in the decade that followed. A relationship is explored between First Amendment theory and structural archetypes of constitutional argument. Future research could focus on international law and contemporary challenges involving technology, surveillance and changes in democratic citizenship.

Evaluation Of Crude Larval Protein And Recombinant Somatic Protein 26/23 (Rhcp26/23) Immunization Against Haemonchus Contortus In Sheep, Omnia M. Kandil, Khaled A. Abdelrahman, Hatem A. Shalaby, Seham H.M. Hendawy, Nadia M.T. Abu El Ezz, Somia A. Nassar, James E. Miller

Faculty Publications

© Kandil, et al. Aim: The aim of this study was to evaluate the potential possibility of crude larval and recombinant (rHcp26/23) antigens of Haemonchus contortus for immunization to control sheep hemonchosis. Materials and Methods: A total of 21 lambs were divided into five groups. Lambs were immunized with larval and recombinant (rHcp26/23) proteins at day 0 and day 14 and after that challenged with 5000 infective larvae of H. contortus on day 42. An unvaccinated positive control group was challenged with L3 in the meantime. An unvaccinated negative control group was not challenged. Results: Fecal egg count reduction taking …

Osteopontin Facilitates West Nile Nirus Neuroinvasion Via Neutrophil "Trojan Horse" Transport, Amber M. Paul, Dhiraj Acharya, Laurel Duty, E. Ashley Thompson, Linda Le, Dobrivoje S. Stokic, A. Arturo Leis, Fengwei Bai

Faculty Publications

West Nile virus (WNV) can cause severe human neurological diseases including encephalitis and meningitis. The mechanisms by which WNV enters the central nervous system (CNS) and host-factors that are involved in WNV neuroinvasion are not completely understood. The proinflammatory chemokine osteopontin (OPN) is induced in multiple neuroinflammatory diseases and is responsible for leukocyte recruitment to sites of its expression. In this study, we found that WNV infection induced OPN expression in both human and mouse cells. Interestingly, WNV-infected OPN deficient (Opn −/−) mice exhibited a higher survival rate (70%) than wild type (WT) control mice (30%), suggesting OPN plays a …

Normal Behavioral Responses To Light And Darkness And The Pupillary Light Reflex Are Dependent Upon The Olivary Pretectal Nucleus In The Diurnal Nile Grass Rat, Andrew J. Gall, Ohanes S. Khacherian, Brandi Ledbetter, Sean P. Deats, Megan Luck, Laura Smale, Lily Yan, Antonio A. Nunez

Faculty Publications

The olivary pretectal nucleus (OPT) is a midbrain structure that receives reciprocal bilateral retinal projections, is involved in the pupillary light reflex, and connects reciprocally with the intergeniculate leaflet (IGL), a retinorecipient brain region that mediates behavioral responses to light pulses (i.e., masking) in diurnal Nile grass rats. Here, we lesioned the OPT and evaluated behavioral responses in grass rats to various lighting conditions, as well as their anxiety-like responses to light exposure. While control grass rats remained diurnal, grass rats with OPT lesions exhibited a more night-active pattern under 12h:12h light-dark (LD) conditions. However, when placed in constant darkness, …