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Articles 1261 - 1290 of 6811
Full-Text Articles in Entire DC Network
Long‐Term Monitoring Reveals Differential Responses Mussel And Host Fish Communities In A Biodiversity Hotspot, Irene Sanchez Gonzalez, Garrett W. Hopper, Jamie Bucholz, Carla L. Atkinson
Long‐Term Monitoring Reveals Differential Responses Mussel And Host Fish Communities In A Biodiversity Hotspot, Irene Sanchez Gonzalez, Garrett W. Hopper, Jamie Bucholz, Carla L. Atkinson
Faculty Publications
Biodiversity hotspots can serve as protected areas that aid in species conservation. Long-term monitoring of multiple taxonomic groups within biodiversity hotspots can offer insight into factors influencing their dynamics. Mussels (Bivalvia: Unionidae) and fish are highly diverse and imperiled groups of organisms with contrasting life histories that should influence their response to ecological factors associated with local and global change. Here we use historical and contempo-rary fish and mussel survey data to assess fish and mussel community changes over a 33 year period (1986–2019) and relationships between mussel abundance and their host fish abundance in Bogue Chitto Creek, a tributary …
Revamping Ecosystem Services Through Agroecology—The Case Of Cereals, Gomathy Sethuraman, Nurul Amalina Mohd Zain, Sumiani Yusoff, Yin Mei Ng, Niranjan Baisakh, Acga Cheng
Revamping Ecosystem Services Through Agroecology—The Case Of Cereals, Gomathy Sethuraman, Nurul Amalina Mohd Zain, Sumiani Yusoff, Yin Mei Ng, Niranjan Baisakh, Acga Cheng
Faculty Publications
Globally, farming systems are mostly dominated by monoculture, which has the advantage of profitability at the expense of ecological systems. Recent years have witnessed an increasing mo-mentum in global efforts to deploy sustainable agriculture practices that mimic ecological processes, with agroecology at the forefront. In addition to the ecological aspect, agroecology also encompasses economic and social aspects targeting the whole food system. Transformative agroecology has been recognized as a stepping stone to achieving several Sustainable Development Goals (SDGs), due to its great potential to build climate change-resilient farming systems while enhancing ecosystem services and reducing biodiversity loss. Nonetheless, the available …
The God Who Is Affected By Human Problems: Atonement Through Israelite Purification Offerings, Roy E. Gane
The God Who Is Affected By Human Problems: Atonement Through Israelite Purification Offerings, Roy E. Gane
Faculty Publications
No abstract provided.
No Evidence That Salt Water Ingestion Kills Adult Mosquitoes (Diptera: Culicidae), Donald A. Yee, Catherine Dean, Cameron Webb, Jennifer A. Henke, Gabriela Perezchica-Harvey, Gregory S. White, Ary Faraji, Joshua D. Macaluso, Rebecca Christofferson
No Evidence That Salt Water Ingestion Kills Adult Mosquitoes (Diptera: Culicidae), Donald A. Yee, Catherine Dean, Cameron Webb, Jennifer A. Henke, Gabriela Perezchica-Harvey, Gregory S. White, Ary Faraji, Joshua D. Macaluso, Rebecca Christofferson
Faculty Publications
Various products and insecticides are available that purport to reduce wild populations of adult mosquitoes. Recently, several manufacturers and general public comments on the internet have promoted devices that claim that ingestion of salt will significantly reduce populations of wild mosquitoes to near zero; there are no known scientific efficacy data that support these claims. We tested the survival of nine mosquito species of pest and public health importance across four adult diets: Water Only, Sugar Water Only (8.00%), Salt Water Only (1.03%), and Sugar + Salt Water. Species included the following: Aedes aegypti (L.), Aedes albopictus (Skuse), Aedes dorsalis …
Prospects For Gulf Of Mexico Environmental Recovery And Restoration, Denis A. Wiesenburg, Bob Shipp, F. Joel Fodrie, Sean Powers, Julien Lartigue, Kelly M. Darnell, Melissa M. Baustian, Cam Ngo, John F. Valentine, Kateryna Wowk
Prospects For Gulf Of Mexico Environmental Recovery And Restoration, Denis A. Wiesenburg, Bob Shipp, F. Joel Fodrie, Sean Powers, Julien Lartigue, Kelly M. Darnell, Melissa M. Baustian, Cam Ngo, John F. Valentine, Kateryna Wowk
Faculty Publications
Previous oil spills provide clear evidence that ecosystem restoration efforts are challenging, and recovery can take decades. Similar to the Ixtoc 1 well blowout in 1979, the Deepwater Horizon (DWH) oil spill was enormous both in volume of oil spilled and duration, resulting in environmental impacts from the deep ocean to the Gulf of Mexico coastline. Data collected during the National Resource Damage Assessment showed significant damage to coastal areas (especially marshes), marine organisms, and deep-sea habitat. Previous spills have shown that disparate regions recover at different rates, with especially long-term effects in salt marshes and deepsea habitat. Environmental recovery …
Elaborating The Science Of Food Choice For Rapidly Changing Food Systems In Low-And Middle-Income Countries, Christine E. Blake Ph.D., Rd, Edward A. Frongillo Jr. Ph.D., Andrea M. Warren, Shilpa V. Constantinides, Krystal K. Rampalli, Shiva Bhandari
Elaborating The Science Of Food Choice For Rapidly Changing Food Systems In Low-And Middle-Income Countries, Christine E. Blake Ph.D., Rd, Edward A. Frongillo Jr. Ph.D., Andrea M. Warren, Shilpa V. Constantinides, Krystal K. Rampalli, Shiva Bhandari
Faculty Publications
The world’s food systems and environments have been changing dramatically, concomitant with changes in overand undernutrition. We elaborate the science of food choice to better understand, analyze, and respond to relationships between changing food environments and food choice. The science of food choice is concerned with generating knowledge about causal drivers of food choice decision making processes and behavior within immediate food and social environments. Three fundamental and interconnected questions undergird this science; 1) what do people eat from the options available and accessible?; 2) how do people interact with food environments?; and 3) why do people decide to acquire, …
The Costs Of Dissent: Protest And Civil Liabilities, Timothy Zick
The Costs Of Dissent: Protest And Civil Liabilities, Timothy Zick
Faculty Publications
This Article examines the civil costs and liabilities that apply to individuals who organize, participate in, and support protest activities. Costs ranging from permit fees to punitive damages significantly affect First Amendment speech, assembly, and petition rights. A variety of common law and statutory civil claims also apply to protest activities. Plaintiffs have recently filed a number of new civil actions negatively affecting protest, including "negligent protest," "aiding and abetting defamation," "riot boosting," "conspiracy to protest," and "tortious petitioning." The labels are suggestive of the threats these suits pose to First Amendment rights. All of these costs and liabilities add …
Maternal Dietary Quality, Inflammatory Potential And Childhood Adiposity: An Individual Participant Data Pooled Analysis Of Seven European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Mark Hanson, Keith M. Godfrey, Romy Gaillard, Liesbeth Duijts, Barbara Heude, James Hébert Scd, Fionnuala M. Mcauliffe, Cecily Kelleher, Catherine M. Phillips
Maternal Dietary Quality, Inflammatory Potential And Childhood Adiposity: An Individual Participant Data Pooled Analysis Of Seven European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Mark Hanson, Keith M. Godfrey, Romy Gaillard, Liesbeth Duijts, Barbara Heude, James Hébert Scd, Fionnuala M. Mcauliffe, Cecily Kelleher, Catherine M. Phillips
Faculty Publications
Background
Mounting evidence suggests that maternal diet influences pregnancy and birth outcomes, but its contribution to the global epidemic of childhood obesity has not as yet been definitively characterized. We investigated whether maternal whole diet quality and inflammatory potential influence childhood adiposity.
Methods
We harmonized and pooled individual participant data from 16,295 mother-child pairs in seven European birth cohorts. Maternal pre-, early-, late-, and whole-pregnancy (any time during pregnancy) dietary quality and inflammatory potential assessed with the Dietary Approaches to Stop Hypertension (DASH) score and the energy-adjusted Dietary Inflammatory Index (E-DII™) score, respectively. Primary outcome was childhood overweight and obesity …
Synergies Among Environmental Science Research And Monitoring Networks: A Research Agenda, J. A. Jones, P. M. Groffman, J. Blair, F. W. Davis, H. Dugan, E. E. Euskirchen, Serita D. Frey, T. K. Harms, E. Hinckley, M. Kosmala, S. Loberg, S. Malone, K. Novick, S. Malone, K. Novick, S. Record, A. V. Rocha, B. L. Ruddell, E. H. Stanley, C. Sturtevant, A. Thorpe, T. White, W. R. Wieder, L. Zhai, K. Zhu
Synergies Among Environmental Science Research And Monitoring Networks: A Research Agenda, J. A. Jones, P. M. Groffman, J. Blair, F. W. Davis, H. Dugan, E. E. Euskirchen, Serita D. Frey, T. K. Harms, E. Hinckley, M. Kosmala, S. Loberg, S. Malone, K. Novick, S. Malone, K. Novick, S. Record, A. V. Rocha, B. L. Ruddell, E. H. Stanley, C. Sturtevant, A. Thorpe, T. White, W. R. Wieder, L. Zhai, K. Zhu
Faculty Publications
Many research and monitoring networks in recent decades have provided publicly available data documenting environmental and ecological change, but little is known about the status of efforts to synthesize this information across networks. We convened a working group to assess ongoing and potential cross-network synthesis research and outline opportunities and challenges for the future, focusing on the US-based research network (the US Long-Term Ecological Research network, LTER) and monitoring network (the National Ecological Observatory Network, NEON). LTER-NEON cross-network research synergies arise from the potentials for LTER measurements, experiments, models, and observational studies to provide context and mechanisms for interpreting NEON …
Research Mentor Program At Unh Manchester: Peer Learning Partnerships, Carolyn White Gamtso, Annie Donahue, Kimberly Donovan
Research Mentor Program At Unh Manchester: Peer Learning Partnerships, Carolyn White Gamtso, Annie Donahue, Kimberly Donovan
Faculty Publications
At the University of New Hampshire at Manchester (UNH Manchester), the librarians, the Center for Academic Enrichment (CAE) professional staff, and the First-Year Writing Program faculty established a rich collaboration for supporting undergraduate students throughout the research process. This effort was realized by adapting a highly effective peer-tutoring program, integrating basic information literacy instruction skills into the tutor training curriculum, and incorporating the peer tutors within library instruction classes and activities. This chapter focuses on the current iteration of the Research Mentor Program, describes recent changes to the mentors’ information literacy training, and examines valuable lessons learned throughout the program’s …
The Influence Of Geographic Variation In Vegetation Characteristics On Habitat Use And Productivity Of An Endangered Warbler, Ashley M. Long, Heather A. Mathewson, Michael L. Morrison
The Influence Of Geographic Variation In Vegetation Characteristics On Habitat Use And Productivity Of An Endangered Warbler, Ashley M. Long, Heather A. Mathewson, Michael L. Morrison
Faculty Publications
Understanding how geographic variation in environmental conditions influences species’ distributions and population dynamics is critical for effective management of at-risk species and can help us anticipate wildlife responses to future change. The Golden-cheeked Warbler (Setophaga chrysoparia; hereafter warbler) is an endangered migratory songbird that nests in oak-juniper woodland in Texas. From 2009 to 2013, we monitored 895 warbler territories at 90 study sites located across the warbler's breeding range to examine how geographic variation in vegetation characteristics influenced aspects of warbler habitat selection and productivity. We found range-wide variation in the tree species composition and vegetation structure of warbler habitat. …
Temporal And Spatial Blood Feeding Patterns Of Urban Mosquitoes In The San Juan Metropolitan Area, Puerto Rico, Matthew W. Hopken, Limarie J. Reyes-Torres, Nicole Scavo, Antoinette J. Piaggio, Zaid Abdo, Daniel Taylor, James Pierce, Donald A. Yee
Temporal And Spatial Blood Feeding Patterns Of Urban Mosquitoes In The San Juan Metropolitan Area, Puerto Rico, Matthew W. Hopken, Limarie J. Reyes-Torres, Nicole Scavo, Antoinette J. Piaggio, Zaid Abdo, Daniel Taylor, James Pierce, Donald A. Yee
Faculty Publications
Urban ecosystems are a patchwork of habitats that host a broad diversity of animal species. Insects comprise a large portion of urban biodiversity which includes many pest species, including those that transmit pathogens. Mosquitoes (Diptera: Culicidae) inhabit urban environments and rely on sympatric vertebrate species to complete their life cycles, and in this process transmit pathogens to animals and humans. Given that mosquitoes feed upon vertebrates, they can also act as efficient samplers that facilitate detection of vertebrate species that utilize urban ecosystems. In this study, we analyzed DNA extracted from mosquito blood meals collected temporally in multiple neighborhoods of …
Music, Our Human Superpower, Kristin Lems
Music, Our Human Superpower, Kristin Lems
Faculty Publications
Research about music pervades every discipline because music touches every area of life. Studies revealing the salutary effects of music can be found not only in music educator research, but in research in psychology, speech and hearing, child development, neuroscience, and increasingly, health and wellness, aging, rehabilitation and recovery. Since my focus is especially in the areas of language and literacy, I research the positive effects of music on reading, writing, and learning languages - and of this, there is no shortage. In this brief Academia article, I share what I’d like to call an “homage-with-references” to our great Superpower, …
Documentation Of Atlantic Tarpon (Megalops Atlanticus) Space Use And Move Persistence In The Northern Gulf Of Mexico Facilitated By Angler Advocates, J. Marcus Drymon, Matthew B. Jargowsky, Michael A. Dance, Mitchell Lovell, Crystal Lou Allen Hightower, Amanda E. Jefferson, Andrea M. Kroetz, Sean P. Powers
Documentation Of Atlantic Tarpon (Megalops Atlanticus) Space Use And Move Persistence In The Northern Gulf Of Mexico Facilitated By Angler Advocates, J. Marcus Drymon, Matthew B. Jargowsky, Michael A. Dance, Mitchell Lovell, Crystal Lou Allen Hightower, Amanda E. Jefferson, Andrea M. Kroetz, Sean P. Powers
Faculty Publications
Atlantic tarpon (Megalops atlanticus, hereafter tarpon) are facing a multitude of stressors and are considered Vulnerable by the IUCN; however, significant gaps remain in our understanding of tarpon space use and movement. From 2018 to 2019, citizen scientists facilitated tagging of 23 tarpon with SPOT tags to examine space use and movement across the northern Gulf of Mexico. Movement-based kernel densities were used to estimate simplified biased random bridge-based utilization distributions and a joint move persistence model was used to estimate a behavioral index for each fish. Tarpon showed consistent east–west movement from the Alabama/Florida border to Louisiana, and utilization …
Neural Responses To Happy, Fearful And Angry Faces Of Varying Identities In 5-And 7-Month-Old Infants, Laurie Bayet, Katherine L. Perdue, Hannah F. Behrendt, John E. Richards, Alissa Westerlund, Julia K. Cataldo, Charles A. Nelson Iii
Neural Responses To Happy, Fearful And Angry Faces Of Varying Identities In 5-And 7-Month-Old Infants, Laurie Bayet, Katherine L. Perdue, Hannah F. Behrendt, John E. Richards, Alissa Westerlund, Julia K. Cataldo, Charles A. Nelson Iii
Faculty Publications
The processing of facial emotion is an important social skill that develops throughout infancy and early childhood. Here we investigate the neural underpinnings of the ability to process facial emotion across changes in facial identity in cross-sectional groups of 5- and 7-month-old infants. We simultaneously measured neural metabolic, behavioral, and autonomic responses to happy, fearful, and angry faces of different female models using functional near-infrared spectroscopy (fNIRS), eye-tracking, and heart rate measures. We observed significant neural activation to these facial emotions in a distributed set of frontal and temporal brain regions, and longer looking to the mouth region of angry …
Use Of Taxonomic And Trait-Based Approaches To Evaluate The Effect Of Bt Maize Expressing Cry1ie Protein On Non-Target Collembola: A Case Study In Northeast China, Bai Feng Wang, Feng Ci Wu, Jun Qi Yin, Zhi Lei Jiang, Xin Yuan Song, Gadi V.P. Reddy
Use Of Taxonomic And Trait-Based Approaches To Evaluate The Effect Of Bt Maize Expressing Cry1ie Protein On Non-Target Collembola: A Case Study In Northeast China, Bai Feng Wang, Feng Ci Wu, Jun Qi Yin, Zhi Lei Jiang, Xin Yuan Song, Gadi V.P. Reddy
Faculty Publications
To evaluate the effect of Bt maize expressing Cry1Ie protein on non-target soil Collembola, a two-year field study was conducted in Northeast China. Bt maize line IE09S034 and its near isoline Zong 31 were selected as experimental crops; we investigated the collembolan community using both taxonomic and trait-based approaches, and elucidated the relationship between environmental variables and the collembolan community using redundancy analysis (RDA).The ANOVA results showed that maize variety neither had significant effect on the parameters based on taxonomic approach (abundance, species richness, Shannon–Wiener index, Pielou’s evenness index), nor on the parameters based on trait-based approach (ocelli number, body …
Characterization Of The Spatial Distribution Of Alfalfa Weevil, Hypera Postica, And Its Natural Enemies, Using Geospatial Models, Govinda Shrestha, Jhalendra P. Rijal, Gadi V.P. Reddy
Characterization Of The Spatial Distribution Of Alfalfa Weevil, Hypera Postica, And Its Natural Enemies, Using Geospatial Models, Govinda Shrestha, Jhalendra P. Rijal, Gadi V.P. Reddy
Faculty Publications
BACKGROUND: Understanding the spatio-temporal dynamics of prey and predator distributions can provide valuable insights into pest management strategies and conservation of natural enemies in agro-ecosystems. The alfalfa weevil, Hypera postica (Gyllenhal), is an economically important pest of alfalfa throughout the western United States. Coccinellids and nabids are among the most important natural enemies of this species, contributing to the biological control of H. postica in alfalfa fields. The spatio-temporal dynamics of H. postica and these two predator groups were investigated using 81 (= 9 × 9 grid) sample points in each of five alfalfa fields in north-central Montana. The data …
Disturbed Amazonian Forests Support Diminished Breeding Bird Communities, Cameron L. Rutt, Michael D. Kaller, Philip C. Stouffer
Disturbed Amazonian Forests Support Diminished Breeding Bird Communities, Cameron L. Rutt, Michael D. Kaller, Philip C. Stouffer
Faculty Publications
Twenty percent of the Brazilian Amazon has now been deforested, and deforestation rates are increasing. This compels us to evaluate the conservation potential of human-modified landscapes; yet the ecological value of regenerating and fragmented Amazonian forests remains poorly understood. To date, most faunal studies in disturbed forests have examined metrics derived from presence or abundance. Although valuable, these data cannot tell us how old-growth species are using disturbed forests. In this study, we complement presence data with breeding observations to assess more comprehensively the habitat quality of disturbed forests in central Amazonia. We synthesized breeding evidence from standardized passive mist-netting, …
Exploring The Louisiana Purchase And Its Borderlands: The Lewis And Clark, Hunter And Dunbar, Zebulon Pike, And Freeman And Custis Expeditions In Perspective [Part 2], Jay H. Buckley
Faculty Publications
Simply conducting expeditions was not enough to define the boundaries of the Louisiana Purchase. To be useful, the knowledge of Louisiana that Jefferson’s and Wilkinson’s soldiers and scientists gained from observation and inquiry needed to be interpreted and published. Jefferson’s “Message from the President” delivered to Congress on February 19, 1806, made some of their findings available to the public for the first time. His report informed the world that the Lewis and Clark and Hunter-Dunbar expeditions had collected a wealth of scientific information. It contained Lewis and Clark’s interim report written during the winter of 1804-1805, information documenting Hunter …
Rethinking Grid Governance For The Climate Change Era, Shelley Welton
Rethinking Grid Governance For The Climate Change Era, Shelley Welton
Faculty Publications
The electricity sector is often appropriately called the linchpin of efforts to respond to climate change. Over the next few decades, the U.S. electricity sector will need to double in size to accommodate electric vehicles, at the same time that it transforms to run entirely on clean energy. To drive this transformation, states are increasingly adopting 100% clean energy targets. But fossil fuel corporations are pushing back, seeking to maintain their structural domination of the U.S. energy sector. This article calls attention to one central but under-scrutinized way that these companies impede the clean energy transition: Incumbent fossil fuel companies …
Shared Developmental Trajectories For Fractional Reasoning And Fine Motor Ability In 4 And 5 Year Olds, Lindsey Clark, John Shelley-Tremblay, Julie Cwikla
Shared Developmental Trajectories For Fractional Reasoning And Fine Motor Ability In 4 And 5 Year Olds, Lindsey Clark, John Shelley-Tremblay, Julie Cwikla
Faculty Publications
We investigated preschool-aged children’s understanding of early fractional tasks and how that performance correlates with fine motor skills and use of gestures while counting. Participants were 33 preschoolers aged 4 to 5 in two Southeastern public elementary schools. Children were tested individually in an interview-like setting. Mathematics tasks were presented in a paper and pencil format and the Grooved Pegboard test assessed fine motor skills. Finally, utilization of gestures was evaluated by taking a behavioral rating of the child’s hand morphology, accuracy of gestures, and synchrony of gestures and spoken word while performing a counting task. Results indicate that performance …
A Synthesis Of Deepwater Horizon Impacts On Coastal And Nearshore Living Marine Resources, Steven A. Murawski, Joshua P. Kilborn, Adriana C. Bejarano, David Chagaris, David Donaldson, Frank J. Hernandez, Timothy C. Macdonald, Craig Newton, Ernst Peebles, Kelly L. Robinson
A Synthesis Of Deepwater Horizon Impacts On Coastal And Nearshore Living Marine Resources, Steven A. Murawski, Joshua P. Kilborn, Adriana C. Bejarano, David Chagaris, David Donaldson, Frank J. Hernandez, Timothy C. Macdonald, Craig Newton, Ernst Peebles, Kelly L. Robinson
Faculty Publications
The 2010 Deepwater Horizon (DWH) oil blowout in the Gulf of Mexico began on April 20, originating in the deep sea 66 km off the Louisiana coast. By early June, DWH oil had spread to coastal Louisiana, Mississippi, Alabama and western Florida. An estimated 2,113 km of shoreline were oiled, making DWH the largest marine oil spill in global history by length of affected shoreline. Additionally, a series of oil spill response measures were deployed, including diversions of Mississippi River discharge to forestall oil coming ashore, and the establishment of large-scale fishery closures, with both affecting coastal resources to varying …
Biophysical Characteristics Of Lipid-Induced Aβ Oligomers Correlate To Distinctive Phenotypes In Transgenic Mice, Jhinuk Saha, Dexter N. Dean, Shailendra Dhakal, Kelli A. Stockmal, Sarah E. Morgan, Kristy D. Dillon, Munir F. Adamo, Yona Levites, Vijayaraghavan Rangachari
Biophysical Characteristics Of Lipid-Induced Aβ Oligomers Correlate To Distinctive Phenotypes In Transgenic Mice, Jhinuk Saha, Dexter N. Dean, Shailendra Dhakal, Kelli A. Stockmal, Sarah E. Morgan, Kristy D. Dillon, Munir F. Adamo, Yona Levites, Vijayaraghavan Rangachari
Faculty Publications
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects cognition and memory. Recent advances have helped identify many clinical sub-types in AD. Mounting evidence point toward structural polymorphism among fibrillar aggregates of amyloid-β (Aβ) to being responsible for the phenotypes and clinical manifestations. In the emerging paradigm of polymorphism and prion-like propagation of aggregates in AD, the role of low molecular weight soluble oligomers, which are long known to be the primary toxic agents, in effecting phenotypes remains inconspicuous. In this study, we present the characterization of three soluble oligomers of Aβ42, namely 14LPOs, 16LPOs, and GM1Os with discreet …
Joint Innovation Investment And Pricing Decisions In Retail Supply Chains With Customer Value, Jiali Qu, Benyong Hu, Chao Meng
Joint Innovation Investment And Pricing Decisions In Retail Supply Chains With Customer Value, Jiali Qu, Benyong Hu, Chao Meng
Faculty Publications
In the retail industry, customer value has become the key to maintaining competitive advantages. In the era of new retail, customer value is not only affected by the product price, but it is also closely related to innovations, such as value‐added services and unique business models. In this paper, we study the joint innovation investment and pricing decisions in a retailer–supplier supply chain based on revenue sharing contracts and customer value. We first find that, in the non-cooperative game, equilibrium only exists in the supplier Stackelberg game. However, revenue sharing contracts cannot coordinate the supply chain in the non‐cooperative game. …
The Importance Of Viewing Property As A System, Lynda L. Butler
The Importance Of Viewing Property As A System, Lynda L. Butler
Faculty Publications
Can--or should--the American property system adapt to curb the excesses inherent in the dominant form of capitalism? Those extolling the virtues of privatization of resources would likely answer in the negative. Such a response would ignore the core functions and infrastructure of the American institution of property. This Article discusses the structure of property that enables property law to evolve over time, reacting to changing conditions, recognizing informal customs and usages, and otherwise taking into account important feedbacks. It explains how property provides an ordering system of concepts and principles that define and govern relations between a society and its …
Pharmacokinetics And Pharmacodynamics Of Immediate- And Modified-Release Mycophenolic Acid Preparations In Healthy Beagle Dogs, Micheal Klotsman, Sebastien Coquery, Gayatri Sathyan, Vatsala Naageshwaran, Paddy Shivanand, Amanda J. Fairchild, Oliver A. Garden, Wayne H. Anderson
Pharmacokinetics And Pharmacodynamics Of Immediate- And Modified-Release Mycophenolic Acid Preparations In Healthy Beagle Dogs, Micheal Klotsman, Sebastien Coquery, Gayatri Sathyan, Vatsala Naageshwaran, Paddy Shivanand, Amanda J. Fairchild, Oliver A. Garden, Wayne H. Anderson
Faculty Publications
Background: Mycophenolic acid (MPA) is a broad-acting immunomodulating agent that may be therapeutically beneficial for the treatment of immune-mediated diseases in canine patients.
Objectives: To determine the suppressive effects of MPA on T-cell proliferation, and to assess the feasibility of a canine-specific q24 h modified-release MPA formulation (OKV-1001b).
Animals: Fifteen healthy purpose-bred male beagle dogs.
Methods: Two nearly identical open-label fifteen-day studies were conducted in which dogs were randomized to receive mycophenolate mofetil (MMF; 10 mg/kg q12h), or two doses of OKV-1001b (270 mg and 180 mg; q24h). Serial pharmacokinetic (PK) and pharmacodynamic (PD) samples were collected on Days 1, …
Structural Insights Into The Disruption Of Tnf-Tnfr1 Signalling By Small Molecules Stabilising A Distorted Tnf, David Mcmillan, Carlos Martinez-Fleites, John Porter, David Fox, Rachel E. Davis, Prashant Mori, Tom Ceska, Bruce Carrington, Alastair Lawson, Tim Bourne, James O'Connell
Structural Insights Into The Disruption Of Tnf-Tnfr1 Signalling By Small Molecules Stabilising A Distorted Tnf, David Mcmillan, Carlos Martinez-Fleites, John Porter, David Fox, Rachel E. Davis, Prashant Mori, Tom Ceska, Bruce Carrington, Alastair Lawson, Tim Bourne, James O'Connell
Faculty Publications
Tumour necrosis factor (TNF) is a trimeric protein which signals through two membrane receptors, TNFR1 and TNFR2. Previously, we identified small molecules that inhibit human TNF by stabilising a distorted trimer and reduce the number of receptors bound to TNF from three to two. Here we present a biochemical and structural characterisation of the small molecule-stabilised TNF-TNFR1 complex, providing insights into how a distorted TNF trimer can alter signalling function. We demonstrate that the inhibitors reduce the binding affinity of TNF to the third TNFR1 molecule. In support of this, we show by X-ray crystallography that the inhibitor-bound, distorted, TNF …
Aircraft-Based Inversions Quantify The Importance Of Wetlands And Livestock For Upper Midwest Methane Emissions, Xueying Yu, Dylan B. Millet, Kelley C. Wells, Daven K. Henze, Hansen Cao, Timothy J. Griffis, Eric A. Kort, Genevieve Plant, Malte J. Deventer, Randall K. Kolka, D. Tyler Roman, Kenneth J. Davis, Ankur R. Desai, Bianca C. Baier, Kathryn Mckain, Alan C. Czarnetzki, A. Anthony Bloom
Aircraft-Based Inversions Quantify The Importance Of Wetlands And Livestock For Upper Midwest Methane Emissions, Xueying Yu, Dylan B. Millet, Kelley C. Wells, Daven K. Henze, Hansen Cao, Timothy J. Griffis, Eric A. Kort, Genevieve Plant, Malte J. Deventer, Randall K. Kolka, D. Tyler Roman, Kenneth J. Davis, Ankur R. Desai, Bianca C. Baier, Kathryn Mckain, Alan C. Czarnetzki, A. Anthony Bloom
Faculty Publications
We apply airborne measurements across three seasons (summer, winter and spring 2017-2018) in a multi-inversion framework to quantify methane emissions from the US Corn Belt and Upper Midwest, a key agricultural and wetland source region. Combing our seasonal results with prior fall values we find that wetlands are the largest regional methane source (32 %, 20 [16-23] Gg/d), while livestock (enteric/manure; 25 %, 15 [14-17] Gg/d) are the largest anthropogenic source. Natural gas/petroleum, waste/landfills, and coal mines collectively make up the remainder. Optimized fluxes improve model agreement with independent datasets within and beyond the study timeframe. Inversions reveal coherent and …
Linking Genes To Traits In Fungi, A. L. Romero-Olivares, Eric W. Morrison, A. Pringle, Serita D. Frey
Linking Genes To Traits In Fungi, A. L. Romero-Olivares, Eric W. Morrison, A. Pringle, Serita D. Frey
Faculty Publications
Fungi are mediators of the nitrogen and carbon cycles in terrestrial ecosystems. Examining how nitrogen uptake and organic matter decomposition potential differs in fungi can provide insight into the underlying mechanisms driving fungal ecological processes and ecosystem functioning. In this study, we assessed the frequency of genes encoding for specific enzymes that facilitate nitrogen uptake and organic matter decomposition in 879 fungal genomes with fungal taxa grouped into trait-based categories. Our linked gene-trait data approach revealed that gene frequencies vary across and within trait-based groups and that trait-based categories differ in trait space. We present two examples of how this …
Associations Of Maternal Dietary Inflammatory Potential And Quality With Offspring Birth Outcomes: An Individual Participant Data Pooled Analysis Of 7 European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Elzbieta Trafalska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Liesbeth Duijts, Barbara Heude, James R. Hébert Scd, Fionnuala M. Mcauliffe, Cecily C. Kelleher, Catherine M. Phillips
Associations Of Maternal Dietary Inflammatory Potential And Quality With Offspring Birth Outcomes: An Individual Participant Data Pooled Analysis Of 7 European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Elzbieta Trafalska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Liesbeth Duijts, Barbara Heude, James R. Hébert Scd, Fionnuala M. Mcauliffe, Cecily C. Kelleher, Catherine M. Phillips
Faculty Publications
Background
Adverse birth outcomes are major causes of morbidity and mortality during childhood and associate with a higher risk of noncommunicable diseases in adult life. Maternal periconception and antenatal nutrition, mostly focusing on single nutrients or foods, has been shown to influence infant birth outcomes. However, evidence on whole diet that considers complex nutrient and food interaction is rare and conflicting. We aim to elucidate the influence of whole-diet maternal dietary inflammatory potential and quality during periconceptional and antenatal periods on birth outcomes.
Methods and findings
We harmonized and pooled individual participant data (IPD) from up to 24,861 mother–child pairs …