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The Effect Of Ethanol On Skeletal Muscle Endocrine Function And The Novel Myokines Myonectin And Irisin, Kendra Hagood

Electronic Theses and Dissertations

Excessive alcohol consumption is a leading cause of death and disability globally and can lead to diseases such as alcoholic skeletal myopathy. Skeletal muscle is the largest organ in the human body and functions to regulate whole-body energy homeostasis. Additionally, skeletal muscle can function as an endocrine organ via secretion of myokines. Two myokines, myonectin and irisin, present a wide range of effects upon metabolism, inflammation, and tissue survival- signaling. We hypothesized that chronic alcohol consumption will result in reduced circulating myonectin and irisin levels. Mice were fed an ethanol-containing or control diet for 10 days or 6 weeks. Tissues …

A Fractured Conversation : The Professional, Scholarly, And Disciplinary Identities Of Two-Year College Writing Faculty., Laura Sceniak Matravers

Electronic Theses and Dissertations

At a time when state-sponsored policies for tuition-free two-year college education are on the rise, this dissertation examines the place of two-year colleges within the primary discourses circulated within Composition Studies. Specifically, through its investigation of the professional practices and identities of two-year college writing faculty—who work in institutions that are often mistakenly seen as “devoid” of scholarship—this dissertation interrogates disciplinary conceptions of scholarship. This study was comprised of two modes of data collection: an examination of publication trends in prominent Composition Studies journals, and interviews with seven community college writing teachers in the Southeast. This dissertation finds that, in …

Cost Burden Of Social Isolation For Wheelchair Users In Louisville, Kentucky., Connie Light

Electronic Theses and Dissertations

Background: Social isolation is an important predictor for poor health status, chronic diseases, and healthcare utilization and costs. There is a growing number of Americans with one or more disabilities, and evidence suggests that many are also socially isolated. This is especially true for those with immobility, as the built environment including housing structures are not universally designed to be accommodating. Immobility describes those who use walkers, canes, or wheelchairs, with the latter suffering the most impact. The cost of social exclusion can be measured by the exacerbation of disease in wheelchair users, whose fragile health status and social networks …

Exercise Preconditioning And Tfam Overexpression Diminish Skeletal Muscle Atrophy., Nicholas Todd Theilen

Electronic Theses and Dissertations

This dissertation is an analysis of skeletal muscle atrophy and a molecular assessment of potential preventative treatments. Chapter I begins with a background of skeletal muscle atrophy along with an analysis of associated molecular pathways. Here, we discuss how skeletal muscle atrophy is the consequence of protein degradation exceeding protein synthesis and can occur when a muscle is abnormally disused. The development of therapies prior to skeletal muscle atrophy settings to diminish protein degradation is scarce and could be useful to prevent negative clinical outcomes of patients who must unload and disuse musculature over extended periods. Mitochondrial dysfunction is associated …

“You Can’T Put A Price On Something That’S Not For Sale”: Eminent Domain In St. Paul, Virginia (1970 - 1985), Evan Couch

Electronic Theses and Dissertations

The St. Paul Redevelopment Project was unique and touted as the first-of-its-kind to feature cooperation from all three levels of government. Several government agencies helped St. Paul accomplish an “impossible dream,” spending an estimated thirty million dollars to rechannel the Clinch River in the 1970s and 1980s. The small town of 1,000 residentsrelocated 100 families from South St. Paul to carry out the project, much to the dismay of many of the residents. A primary factor in enforcing the power of eminent domain in the St. Paul Redevelopment Project was the idea of “progress,” a commonality of many redevelopment projects. …

Identification Of “Fhua” Like Genes In Rhizobium Leguminosarum Atcc 14479 And Its Role In Vicibactin Transport And Investigation Of Heme Bound Iron Uptake System, Sushant Khanal

Electronic Theses and Dissertations

Siderophores are low molecular weight, iron chelating compounds produced by many bacteria for uptake of iron in case of iron scarcity. Vicibactin is a trihydroxamate type siderophore produced by Rhizobium leguminosarum bv. trifolii ATCC 14479. This work focuses on identifying an outer membrane receptor involved in the transport of vicibactin. We have confirmed the presence of the putative fhuA gene in R. leguminosarum bv. trifolii ATCC 14479. This bacteria shows mutualistic symbiosis with the red clover plant Trifoliium prantense. Leghemoglobin, with its cofactor heme is present in the plant root nodules that surrounds the infecting organism present in the nodules. …

The Impact Of A Sixth Grade Laptop Initiative On Student Attitudes Concerning Their Learning And Technological Competencies, Jamie Jordan

Electronic Theses and Dissertations

This research explored the impact of a sixth grade one-to-one laptop initiative on student attitudes about learning and technological competencies. The study compared student preintervention and postintervention survey data prior to and after a sixth grade laptop intervention initiative. The survey responses were divided into 5 dimensions (School Subject Attitudes, Teaching and Learning Preferences, Computer Use Perceptions, Technology Skills, and Personal Attitudes and Behaviors) on both pre- and postsurveys. District means were compared with preintervention and postintervention data, as well as the means from the 5 dimensions, using a one-sample t-test with a midpoint test value of 3 on a …

Does Spaceflight Increase The Chance Of Female Astronauts Developing Uterine Cancer?, Areej Mosa

Electronic Theses and Dissertations

One of the main questions put forth by NASA and the European Space Agency (ESA) is whether or not an organism, especially mankind, can complete an entire life cycle in space. With this in mind, it is essential to study the effect of spaceflight on reproductive tissues. Using simulated microgravity techniques and whole-body radiation we sought to determine if females subjected to a simulated spaceflight environment have increased incidences of uterine cancer. Uterine tissue from mice subjected to simulated spaceflight was analyzed using immunohistochemical staining and western blot analysis. Two pathways commonly activated in cancer were investigated. Additionally, the uterine …

Attitudes And General Knowledge Of Affirmative Action In Higher Education Admissions At One Historically Black University In Tennessee, James E. Peters

Electronic Theses and Dissertations

The purpose of this study was to examine attitudes and general knowledge of Affirmative Action in higher education admissions at one HBCU in Tennessee. The researcher used a modified version of the Echols’s Affirmative Action Inventory (EAAI) to assess attitudes and general knowledge of all administrators, faculty, staff, and students at this institution. At the conclusion of the collection period, 269 surveys were deemed usable. Of these, 31 surveys were completed by administrators, faculty completed 62 surveys, 55 surveys were completed by staff, and 121 surveys were completed by students. The dependent variables for the study were individual survey questions …

Tcap Assessment In Correlation With And As Compared By Star Assessment, Brooke Sampson

Electronic Theses and Dissertations

The purpose of the study was twofold. The first purpose of the study was to determine if a correlation existed between the Standardized Test for the Assessment of Reading (STAR), created and distributed by Renaissance, and the Tennessee Comprehensive Assessment Program (TCAP) Achievement Test in Math and Reading for grade 3, grade 4, and grade 5. The second purpose of this study was to evaluate the relationship between the percentile category of the STAR test and the TCAP test. The factor variable, identified as the percentile category, included three levels: Urgent Intervention, Intervention, and At/Beyond Benchmark. The dependent variable was …

A Survey Of The Implementation And Usage Of Electronic Dental Records And Digital Radiographs In Private Dental Practices In Mississippi, Barbara K. Brent

Electronic Theses and Dissertations

Implementation of electronic health records by the Health Information Technology for Economic and Clinical Health has led to the implementation of electronic dental records (EDRs) and digital radiography in dental offices. The purpose of this study was to determine the state of the implementation and usage of EDRs and digital radiographs by the private general and pediatric dental practices in Mississippi as well as reasons why the dental practices are not moving forward with the advanced technology.

A survey was emailed to 712 dental practices: 116 responded (16% response rate), and 104 consented to participate (89.66%). Results indicated dental practices …

A Phenomenological Study On Teacher Perception Of Change In School Culture As A Result Of The Implementation Of Mindfulness, Justin Penley

Electronic Theses and Dissertations

A qualitative investigation was conducted to explore the phenomenon of teacher perception of change in school culture as a result of the implementation of mindfulness. This study used a phenomenological methodology, enabling the researcher to gather information by focusing on and describing the impact of mindfulness on school culture in a deep comprehensive manner.

The investigator was able to extract meaning and code data, leading to the emergence of themes that supported and aligned with the study’s research questions and thus led into a holistic understanding of the phenomenon. This was accomplished through data analysis of rich, in-depth interviews, onsite …

Hiv-Related Knowledge, Attitudes, And Behaviors In Two Low Resource Settings, Candice Lynn Collins

Electronic Theses and Dissertations

Two Human Immunodeficiency Virus (HIV) outbreaks occurred almost simultaneously in the United States (US) (2014-2015) and in Cambodia (2015). Information is lacking on HIV-related knowledge, stigmatizing attitudes, and high-risk behaviors (KAB) among the general population, which may affect the transmission of HIV and lead to outbreaks. The current study aimed to: 1) assess KAB among the general population in a high-risk county in the US, 2) analyze KAB among the general population of Cambodia, and 3) compare KAB across samples from a high-risk county in Northeast Tennessee and a province in Cambodia. Tennessee data were collected in 2017 and Cambodian …

The Inclusive Classroom: Perceptions Of General And Special Educators’ Preparedness To Meet The Needs Of Students With Disabilities, Allecia Frizzell

Electronic Theses and Dissertations

This study was designed to determine whether kindergarten through eighth grade general education teachers and special education teachers were prepared to meet the needs of students with disabilities in inclusive classrooms. Conducted in Northeast Tennessee, an online survey was used to collect responses from participants in six school districts. The survey focused on four dimensions including perceptions of preparedness, attitudes towards inclusion, perceptions of administrator support and perceptions of self-efficacy. Data collected from 180 respondents were analyzed and informed the results of this study.

Findings indicated that special education teachers reported significantly higher levels of preparedness to meet the needs …

Success Rates Of Second Semester Anatomy Students In Online And On-Ground Classes At A Community College In East Tennessee, William Sproat

Electronic Theses and Dissertations

Educators expect the number of institutions offering online courses and the number of students enrolling in these courses to increase as many students, particularly nontraditional students, discover the advantages of online content delivery. Online courses require new methods of communication between students and faculty as well as discovering new ways to build relationships, earn student trust, conduct appropriate assessment, and deliver useful course content. Many institutions—public, private, and for-profit—offer a wide variety of online coursework but faculty, employers, and the public have expressed concerns about the quality of online course content. In particular, online delivery of coursework in the natural …

A School Of Choice: A Case Study Of An Instructional Learning Model In A Public School System, Samuel Mccord

Electronic Theses and Dissertations

This case study focused on the understandings of the administration and teaching staff with regard to the implementation and student academic growth of the B-L Upward program. The understandings were formed from data collected through structured, face-to-face interviews. The questioning of the staff members assisted in determining an understanding of the instructional model of the B-L Upward program. The experimental nature of the B-L Upward program allowed students, primarily those graduating from eighth grade and heading into high school, to choose an alternative to the traditional secondary learning environment. The current case study is an examination of the B-L Upward …

Teacher Perceptions Of The Tennessee Educator Acceleration Model (Team), Kelley Harrell

Electronic Theses and Dissertations

The purpose of this quantitative study was to determine the perceptions of Pre K through 8th grade Tennessee teachers about the impact of Tennessee Educator Acceleration Model (TEAM) evaluations on classroom instructional strategies, teacher planning, professional development and teacher effectiveness. Participants in this study were PK-8 public school teachers from 2 districts in Northeast Tennessee who had been evaluated using the Tennessee Educator Acceleration Model (TEAM). Specifically this research was guided by 8 research questions on perceived changes in instructional strategies utilized by teachers, the perceived changes in teacher planning practices and lesson preparation, the perceived changes in professional development …

Exploration Of Rape Myths Among Former Military Professionals, Gabrielle Caldara

Electronic Theses and Dissertations

Sexual violence is sometimes considered a taboo topic for discussion, but it gained widespread attention in the media in late 2017 due to the social movements addressing the sexual assault of women. However, sexual violence perpetrated against men lacks publicity in America, and highlights a similar situation in the Armed Forces. A discussion of sexually violent acts committed against men is sometimes impeded by cultural norms. This discrepancy associated with civilian and military communities inspired this exploratory study.

A convenience sample of 520 former American military professionals completed an anonymous online survey to describe their attitudes and beliefs regarding rape …

Parent And Teacher Perceptions Of Elementary School Homework, Jimmy Marcum

Electronic Theses and Dissertations

The purpose of this qualitative study was to examine the perceptions of parents and teachers of elementary school students regarding homework. Specifically, the researcher examined parent and teacher perceptions, perceptions of teachers in kindergarten through fifth grades, and parents of elementary students in kindergarten through fifth grades. In this qualitative study, the researcher analyzed feedback obtained from two focus groups: a group of three parents and a group of three teachers. One-on-one in-depth interviews of seven parents or guardians and seven elementary school teachers were utilized. These interviews were conducted in settings chosen by the participants. All participants worked in, …

Factors Impacting Bone Mineral Density (Bmd) Results Of Individuals With Intellectual And Developmental Disabilities (Idd), Rhonda Mcnabb

Electronic Theses and Dissertations

Individuals with intellectual and developmental disabilities (IDD) are prone to certain diseases in their lifetime, such as osteoporosis. Absorption of calcium is essential to maintaining good bone health and preventing osteoporosis. This study examined primary care providers’ (PCPs) choice of calcium supplementation, as well as type of calcium supplementation, and the relationship between variables in the IDD population. Ten PCPs were asked to complete a 14-question web-based survey, with five surveys completed. Calcium citrate was the preferred supplement among respondents at 50%. Retrospective data was collected from patient records and included type of calcium supplement prescribed, bone density test results, …

Eggplants And Peaches: Understanding Emoji Usage On Grindr, Emeka E. Moses

Electronic Theses and Dissertations

This study focuses on how gay men communicate on the Grindr dating app. Prior research has been conducted on how gay men construct their online identities, however, few studies explore how gay men experience interactions online, negotiate their relationships with other men online, and perceive other users. The researcher conducted in-depth interviews with 20 men who use the Grinder app, a location-based dating app used by men who have sex with men. Additional data were collected by observing user profiles on the app, which is free and public. This comprehensive, qualitative study of gay men who use Grindr provides insights …

Preschool Teachers' Perceptions Of Children Prenatally Exposed To Drugs, Brandie D. Maness

Electronic Theses and Dissertations

With the incidence of prenatal drug exposure increasing, it is important that preschool teachers are prepared and confident in serving the needs of children affected by this exposure. Teachers need more training and education to prepare them for working with children with prenatal drug exposure.

The purpose of this sequential mixed-methods study was to explore the perceptions, training, and shared experiences of preschool teachers when working with 4- and 5-year-old preschool children who have experienced prenatal drug exposure. The researcher invited 77 preschool teachers in northeast Tennessee working in either Head Start or Tennessee Voluntary Pre-K Initiative programs to complete …

Teachers And Their Perceptions About Adaptive Skill Training Within An Early Childhood Comprehensive Development Classroom For Students With Intellectual Disabilities, Jennifer R. Lynberg

Electronic Theses and Dissertations

This dissertation investigated teacher perceptions about adaptive skill training within an early childhood comprehensive development classroom for students with intellectual disabilities. The purpose of this study was to gain a better understanding about adaptive skills from a teacher's perspective. The aims of the study were to help educators understand the role of comfort level, importance of adaptive skills, planning for adaptive skills, and connecting adaptive skills to an academic outcome. A quantitative, cross-sectional design was used, and an online survey was completed by 254 special education teachers. The participants that completed the survey were 93% female and on average had …

Myths, Risks, And Ignorance: Western Media And Health Experts’ Representations Of Cultures In Ebola-Affected West African Communities, Samson Wonnah

Electronic Theses and Dissertations

The 2014 Ebola outbreak, mostly affecting Liberia, Sierra Leone, and Guinea, is the largest ever recorded. The Ebola response encountered resistance in some affected communities, where some residents accused relief agencies from the Global North of denigrating local cultures. This thesis examines mainstream Western media and health experts’ representation of culture in the Ebola-affected region and employed Foucauldian analysis of discursive power to discuss the impact of such a representation on the concerned communities. Through a content analysis of selected journal and news articles by Western scholars and media and official reports by some relief agencies involved with the Ebola …

Vector Partitions, Jennifer French

Electronic Theses and Dissertations

Integer partitions have been studied by many mathematicians over hundreds of years. Many identities exist between integer partitions, such as Euler’s discovery that every number has the same amount of partitions into distinct parts as into odd parts. These identities can be proven using methods such as conjugation or generating functions. Over the years, mathematicians have worked to expand partition identities to vectors. In 1963, M. S. Cheema proved that every vector has the same number of partitions into distinct vectors as into vectors with at least one component odd. This parallels Euler’s result for integer partitions. The primary purpose …

Precalculus And Act: A Quantitative Study Of Five Tennessee High Schools, Michelle R. Phipps

Electronic Theses and Dissertations

The purpose of this study was to determine if students scored significantly higher on the ACT after taking precalculus than they had scored on the ACT prior to taking precalculus. The researcher investigated whether there is an increase, not only in ACT composite scores, but also in ACT math subtest scores after high school students completed a precalculus course. The researcher also investigated differences regarding gender, socio-economic status, and race.

Five Tennessee high schools from four counties and five different districts were used in this study. The study involved 208 participants and covered a span of three years. The findings …

Fossil Moles From The Gray Fossil Site, Tn: Implications For Diversification And Evolution Of North American Talpidae, Danielle Oberg

Electronic Theses and Dissertations

The Gray Fossil Site (GFS) is one of the richest Cenozoic terrestrial localities in the eastern United States. This study describes the first talpid specimens recovered from the GFS. Using measurements and comparisons of dental and humerus morphology, I identify 4 talpids (Parascalops nov. sp., Quyania cf. Q. europaea, Mioscalops (= Scalopoides) sp., and an unidentified stem desman) occurring at the GFS. Humeral morphology has been used to diagnose talpid species and study relationships. A geometric morphometric analysis showed that humerus shape is highly reflective of locomotor ecology in extant talpids and allows ecological inferences for fossil …

The American And Swedish Criminal Justice System: A Comparative Study, Josefin Hedstrom

Electronic Theses and Dissertations

Hosting 22 percent of the world’s prison population, the United States is the number one country in the world regarding incarceration rates where 1 in 109 adults are locked up behinds bars and about two-thirds of offenders will recidivate within three years of their release (Durose, Coope, & Snyder, 2014; Kaeble, Glaze, Tsoutis, & Minton, 2016; U.S. Census Bureau, 2015; Walmsley, 2013). Sweden has one of the lowest recidivism and incarceration rates in the world where only 29 percent reoffend and 1 in 2,278 of their total population is behind bars (Kriminalvården, 2017; The World Bank, 2016). The purpose of …

Digging Into Playwriting, Gleason Holt

Electronic Theses and Dissertations

The intent of this thesis was to write an original play and detail the writing process. Themes dealt with in Jane (or, Dug In) are family, coping with grief, survivor’s guilt, and exploration (both literal and personal). In addition to the full script, this thesis explores the inspirations for the play and its title. The play’s genre is analyzed, and reasoning is given for this selection. Included are omitted scenes from the latest draft to offer additional insight into the playwright’s previous versions. A reading of the third draft was presented and detailed in this thesis. A section about future …

Kinetics And Activation Energy Parameters For Hydrolysis Of Acetic Anhydride In A Water-Acetone Cosolvent System, Samson Olowoyo

Electronic Theses and Dissertations

The hydrolysis of acetic anhydride is a widely-studied liquid phase reaction studied since 1906. Different approaches have been used to study the kinetics of this reaction. Approaches used by researchers have involved the use of sophisticated experimental set-ups. In this work, the pH technique has been adopted which involves the use of a pH meter to monitor the hydrolysis reaction. Analysis of the hydrolysis reaction has been performed for water/acetone cosolvent systems over a range of temperatures and mole fractions. Eyring analysis was performed under isomole fraction conditions and activation enthalpy, entropy, and Gibbs free energy for hydrolysis of acetic …