Digital Commons Network^™

Linked Lives In The Riverbed: Integrating Fish Host Dynamics, Community Structure, And Demography For Freshwater Mussel Conservation., Jonathan Patrick Frommeyer

Electronic Theses and Dissertations

Freshwater mussels are long-lived benthic invertebrates that play key roles in nutrient cycling, water filtration, and habitat stability in rivers and streams. Despite their ecological importance, they are among the most imperiled faunal groups in North America, with their persistence increasingly threatened by environmental degradation and disruptions to host–parasite dynamics. This dissertation integrates host ecology, community structure, and demographic modeling to assess population viability and guide conservation priorities for mussel species in Kentucky river systems. The first chapter introduces the ecological context and conservation urgency surrounding freshwater mussels. In particular, emphasizing the need for multi-scale approaches to understand how parasitic …

From Afghanistan To Louisville: Changing Face Of Family And Gender Roles In Afghan Immigrants In Louisville, Kentucky., Zohal Ghoura

Electronic Theses and Dissertations

This study explores how Afghan immigrant families navigate gender roles and domestic responsibilities following their migration to the United States. Although current research recognizes the impact of migration on gender norms and labor division in immigrant families, the lived experiences of Afghan families in the United States remain largely unexplored. Based on 12 in-depth semi-structured interviews with Afghan women, this study explores how cultural expectations, economic constraints, and social context shape the division of domestic responsibilities. Findings reveal that migration opened new opportunities for Afghan women, including sense of freedom, access to education and employment opportunities. Exposure to egalitarian values …

Queer Convergence: Figurative Abstraction In Contemporary Art., Vincent Young

Electronic Theses and Dissertations

This thesis is an exhibition text for the exhibition of the same name held in Schneider Hall Galleries from May 15 to August 21st, 2025. This exhibition explores the work of three contemporary artists – Joshua Jenkins, Drew Scanlon, and Lalana Fedorschak – and analyzes their artwork through the lens of Queer Convergence. Queer Convergence is an exploration of abstracted images of bodies and how we can read these bodies through a queer lens, arguing that the visual language of bodily overlap, melding, and transformation shows the physical form as a site of continual change shaped by shared experience and …

Optimization And Simulation Models For Integrating Social Determinants In Assessing And Optimizing The Accessibility And Efficiency Of Community Pharmacy Networks., Md Morshedul Alam

Electronic Theses and Dissertations

Community pharmacies are essential components of the healthcare system, serving not only as points of medication access but also as providers of health consultations and preventive care. However, disparities in pharmacy access persist due to a combination of geographic, socioeconomic, and behavioral factors. This dissertation develops a comprehensive methodological framework to evaluate and improve accessibility to community pharmacies, integrating optimization, choice modeling, and discrete event simulation. First, we develop an Optimal Community-Pharmacy Assignment (OCPA) model to quantify geographic accessibility across a regional population network. The model minimizes risk-adjusted travel distances between population centers and pharmacies, incorporating social determinants of health …

Remotely-Sensed Urbanization And Local Perceptions Of Change From 1985-2024 In Southern Indiana., Marlea Ferber

Electronic Theses and Dissertations

This study is focused on the land cover change of non-built land cover being transformed into built land cover in two counties in Southern Indiana using mixed methods. Remote sensing was used to identify and quantify land cover change, and interviews were used to understand local perceptions of the physical land cover changes. The study area is situated along the rural-urban continuum with Louisville, Kentucky across the Ohio River. It is important to quantify the amount of land change conversion to built settlement as patterns and rate of urbanization help us to better manage transitions along the rural-urban continuum, but …

A Toi Rna Editing In Three Members Of The Microbotryum Violaceum Fungal Complext And Characterization Of Adar Genes Of Microbotryum Superbum., Shikhi Baruri

Electronic Theses and Dissertations

A-to-I RNA editing is a process that occurs post-transcriptionally. Through this process, adenosine (A) is replaced by inosine (I) in RNAs by adenosine deaminase enzymes that act on the single-stranded RNA. These enzymes, also known as ADARs, act on RNA. The translation and splicing mechanisms subsequently interpret inosine as guanosine (G), which effectively alters genetic information. This kind of RNA alteration can cause both nonsynonymous and synonymous changes in codon, which may have an impact on protein function. A group of over 89 basidiomycete fungal species known as the Microbotryum violaceum complex infects a similarly large group of plant host …

Intestinal Stromal Cells Play A Critical Role In Protection Mediated By Male Microbiota-Derived Metabolites And Androgens Against Disease In Lupus-Prone Mice., Jing Ma

Electronic Theses and Dissertations

Systemic lupus erythematosus (SLE) is a complex autoimmune disease involving broad immune dysregulation. Despite decades of research, most lupus treatments still have limited effectiveness and can cause serious side effects. Both genetic and environmental factors contribute to lupus susceptibility, and a better understanding of how environmental factors influence disease could guide future therapeutic strategies. SLE shows a strong female predominance. Growing evidence implicates the gut microbiota and sex hormones as key environmental contributors to some autoimmune diseases, including lupus. The gut microbiota can influence host immune function, and interestingly, recent studies have revealed sex-bias in microbiota composition and function. Moreover, …

Synthetic And Pharmacological Diversity Of Nitrogen-Containing Heterocycles., Shramana Ghosh

Electronic Theses and Dissertations

Nitrogen-containing heterocycles are a foundational class of compounds in organic chemistry, playing critical roles in pharmaceuticals, agrochemicals, and natural products due to their structural diversity and biological relevance. Among them, isoindolinones are notable for their wide range of pharmacological activities. Structurally, isoindolinones possess a benzylic methylene group adjacent to the nitrogen atom, which allows for selective oxidative transformations to yield phthalimide derivatives, well-known intermediates in synthetic, pharmaceutical, and materials chemistry. Although phthalimide is traditionally employed as a protecting group for amines via the Gabriel synthesis, isoindolinone offers a valuable alternative. Through a modified Gabriel-like approach, isoindolinones can serve as more …

Dust Observations Of Occulting Galaxy Pair Vv 191., Clayton Robertson

Electronic Theses and Dissertations

The presence of dust grains as part of the the interstellar medium (ISM) in galaxies is an all-impactful entity in astronomy due its influence on light, and therefore observations. Unlike a true blackbody, dust absorbs, reflects, reddens, and scatters light within a line of sight. We quantify this phenomena with attenuation: the difference between the observed and true magnitudes of an astronomical object due to dust. Therefore, to map dust attenuation, one needs a known background source of light. In the serendipitous case of partially overlapping –occulting– galaxies, the background galaxy serves as the known light source and the transmission …

Mental Health Service Utilization Among Arab/Middle Eastern In The Us: Structural Disparities, Digital Access, And Stigma-Related Barriers., Fatima M. Aldarweesh

Electronic Theses and Dissertations

Arab Middle Eastern (AME) United States (US) college-attending students are more susceptible to disproportionate mental health problems and underutilization of mental healthcare services due to cultural, structural, and psychosocial barriers. The study examines mental health service utilization and mental health outcomes among AME, particularly focusing on the impact of structural, cultural, and psychosocial determinants grounded in Andersen and Aday’s Health Services research model and Corrigan’s stigma framework. The three interconnected aims use secondary nationally representative data from the Healthy Minds Study (HMS) 2019-2024. The study was analyzed using logistic regression and generalized structural equation modeling across three aims to identify …

Predictor-Informed Bayesian Nonparametric Clustering., Md Yasin Ali Parh

Electronic Theses and Dissertations

In this dissertation, we performed clustering of observations such that the cluster membership is influenced by a set of predictors. To that end, we employ the Bayesian nonparametric Common Atom Model (CAM), which is a nested clustering algorithm that utilizes a (fixed) group membership for each observation to encourage more similar clustering of members of the same group. CAM operates by assuming each group has its own vector of cluster probabilities, which are themselves clustered to allow similar clustering for some groups. We extend this approach by treating the group membership as an unknown latent variable determined as a flexible …

The Influence Of Psychological, Biological, And Social Determinants On Disordered Eating Behaviors Among U.S. Young Adults: Evidence From Nhanes 2015-2018., Samantha Kaye Gerbine

Electronic Theses and Dissertations

Disordered eating behaviors (DEBs) are influenced by biological, social, and psychological factors, yet research often narrowly focuses on White, college-aged women. This study assessed the predictors and prevalence of DEBs in a nationally representative sample of U.S. young adults using data from the 2015–2018 National Health and Nutrition Examination Survey (NHANES). Survey weights were applied to generate national estimates. Descriptive statistics characterized the sample, and logistic regressions tested biological, social, and psychological predictors of DEBs. A composite risk score was developed using variables retained in the final model. The unweighted sample (n = 1,062) represented 64 million U.S. young adults. …

Crossed Stitches: Tension And Transformation In Nineteenth-Century Embroidery Samplers., Hayley Salo

Electronic Theses and Dissertations

Originally designed as practice pieces, embroidery samplers have long been studied as domestic objects and part of sewing history. Interpretations of the material and textual significance of individual samplers is less common. However, recent scholarly attention has turned to using sewing practices and objects as a means for understanding individual stitchers and their contributions to public discourse. As such, a focused study of the material and textual content of embroidery samplers furthers our understanding of the genre on its own and as a wider textile practices. Crossed Stitches is interested in the production, portability, circulation, and reception of embroidery samplers …

"That’S Not A Meal, Bestie”: Humor, Identity, & Feminized Consumption In “Girl Dinner”., Claire Tudor

Electronic Theses and Dissertations

This thesis examines the viral “Girl Dinner” trend as a case study in how gendered consumption, digital identity, and feminist humor intersect in digital spaces. Using “Girl Dinner” as a rhetorical artifact, this thesis explores how women use gendered trends to navigate visibility, labor, and autonomy in online spaces. Through thematic analysis of TikTok content, media coverage, and branded adaptations, the research traces the evolution of the trend from a lighthearted joke to a site of cultural negotiation. This study reveals that while “Girl Dinner” may appear empowering and relatable on the surface, it often reinforces traditional gender expectations under …

Design And Testing Method For Quality Control Of Chill Haze In Bourbon Production., Molly J. Wilburn

Electronic Theses and Dissertations

Chill haze is a quality issue in which white wisps and haze become visible in spirits when reaching sub 0℃ temperatures. Common quality control test methods rely on subjective visual tests and ambient temperature turbidity measurements. Currently there is limited access to commercial devices capable of reaching the sub 0 ℃ temperatures that are required for the formation of chill haze. This thesis focuses on the design, assembly and calibration of a custom-built turbidity meter capable of sub 0 ℃ temperatures and humidity control. The system uses an optical sensor at 90 ° to a light source to detect light …

Rhetorical Analysis Of Kristen Bell's Articulation Of Imperfect Motherhood On Armchair Expert., Sarah J. Neff

Electronic Theses and Dissertations

This thesis explores how Kristen Bell’s articulation of imperfect motherhood, as heard on the popular podcast Armchair Expert, contributes to broader social discourses surrounding motherhood, empowering some mothers while inadvertently constraining others. Using rhetorical analysis grounded in Goffman’s dramaturgical approach, facework theory, and McGee’s theory of fragments, this study explores Bell’s discourse and performance of motherhood within the podcast medium. The podcasting medium provides a rich source for rhetorical analysis due to the long form interview content, and emotionally nuanced content, leading to a stronger connection with the audience. This is evident with the new headlines that follow Bell’s appearance …

Role Of Cardiac Ketone Body Metabolism In Myocardial Perfusion And Exercise Performance., Kara R. Gouwens

Electronic Theses and Dissertations

Cardiorespiratory fitness, a crucial determinant of overall health and a strong predictor of all-cause mortality, is largely dependent on the capacity of the cardiovascular system to deliver oxygen and nutrients. The heart, as the central pump, requires a continuous and adaptable oxygen supply, particularly during increased workload such as occurs with exercise. Impaired myocardial blood flow (MBF) in response to increased demand can lead to ischemia, limiting exercise capacity and potentially causing severe cardiac events. Interestingly, changes in myocardial metabolism and cardiac work correlate with changes in MBF. Therefore, understanding the regulation of MBF, especially the link between local cardiac …

The Substance Of Reality: Moral Perfectionism In Shakespeare's Hamlet., David Wright

Electronic Theses and Dissertations

Through a selection of and close reading of key passages, I offer an interpretation of Hamlet that seeks to illuminate the play as an important work of moral philosophy, and to situate the play within a strand of moral philosophy named moral perfectionism by Stanley Cavell. Indeed, Hamlet is a masterpiece of Renaissance drama, but when read with attention to moral perfectionism, the play yields additional layers of meaning. Hamlet is a “philosophical drama” that navigates the “moral calling of philosophy”—a text that seems to, almost uncannily, elicit the audience to think reflectively, to ask fundamental human questions along …

Bleeding Out From The Redlining: An Autoethnographic Study Of Racial Equity Policy Enactment In A Large, Urban School District., Anderson Aven Cook

Electronic Theses and Dissertations

This autoethnographic study investigates the enactment and impact of racial equity policies within Jefferson County Public Schools (JCPS), a large urban school district in Louisville, Kentucky. The research is motivated by the ongoing challenges of achieving true educational equity for Black and Brown students, a struggle rooted in historical injustices such as redlining. Despite over seven years of policy implementation aimed at promoting racial equity, academic and behavioral disparities between Black and Brown students and their White counterparts have shown little improvement. Utilizing a qualitative methodology, this study employs autoethnography to intertwine personal narrative with scholarly analysis, exploring the lived …

Incarcerated Women: Gendered Rhetoric From The Outside And Reality Inside Prison Walls., Taylor Riley Geiser

Electronic Theses and Dissertations

This dissertation examines how formerly incarcerated women navigate and resist gendered media portrayals through digital platforms, focusing on the “mad” and “bad” woman tropes that shape public perceptions. Drawing on feminist rhetorical theory—particularly Royster and Kirsch’s methodological practices and Ratcliffe’s concept of rhetorical listening—this study combines Critical Discourse Analysis (CDA) of mainstream headlines with Multimodal Discourse Analysis (MDA) of TikTok content. CDA of media coverage surrounding Lori Vallow Daybell, Casey Anthony, and Andrea Yates reveals how language, imagery, and cultural logics sustain harmful binaries that portray women who commit crimes either as depraved or as excused by madness, obscuring the …

Polymathy: The Foundational Source Of Creativity And Innovation., Michael Araki

Electronic Theses and Dissertations

In an era of mounting complexity and a growing need to transcend siloed thinking, this dissertation advances polymathy as a critical yet underexplored construct in the management and behavioral sciences. Polymathy is framed as an expansive approach to the pursuit, development, and application of knowledge, marked by the conjunction of breadth, depth, and integration. Building on a thought lineage that stretches from Ancient Greece through the Renaissance to the present day, this work shows that polymathy is neither a relic of the past nor an achievement reserved for a few—but a mode of being, thinking, and acting in the world …

Material Extrusion 3d Printing Of Metal Alloy: Material, Methods And Application., Sihan Zhang

Electronic Theses and Dissertations

Material extrusion (MEX) additive manufacturing presents a promising pathway for producing metal components with complex geometries while avoiding the safety hazards associated with loose powder handling in conventional metal additive manufacturing processes. This dissertation investigates the development and optimization of MEX processes for aluminum alloys, addressing critical challenges in feedstock formulation, printing parameter optimization, and post-processing strategies. Three distinct approaches were explored to advance the capabilities of aluminum MEX: filament-based processing of 6061 aluminum, paste-based extrusion of 6061 aluminum, and development of a novel aluminum-magnesium-tin alloy system for space manufacturing applications. The filament-based approach successfully demonstrated the production of 6061 …

Genes That Matter: Survival Modeling In Tcga-Brca With Treatment Interactions., David Pratt

Electronic Theses and Dissertations

High-dimensional genomic data offer both promise and challenges for identifying clinically relevant biomarkers. This study developed a parallelized survival modeling pipeline to identify genes associated with overall survival in breast cancer, with a focus on gene-by-treatment interactions and patient heterogeneity. RNA-Seq data from female patients in the TCGA-BRCA cohort were analyzed. Univariate Cox proportional hazards models were used to screen genes, adjusting for age, race/ethnicity, treatment status, and cancer stage. A LASSO-penalized Cox regression was fit across 2000 random seeds to assess feature stability. Genes were filtered by expression level, statistical significance, and hazard ratios (effect sizes) in either direction, …

Engaging In Movement At Work: Exploring Engagement And Physical Activity., Spencer A. Cavan

Electronic Theses and Dissertations

High levels of employee engagement provide organizations competitive advantages such as increased customer satisfaction, profits, and employee productivity. Despite potential benefits, the number of engaged employees is declining and organizations need to find innovative ways to enhance engagement. Emerging evidence suggests workplace physical activity may generate organizational benefits extending beyond health improvement. Therefore, the purpose of this study was to investigate perceptions of engagement among employees participating in a physical activity intervention at work. A qualitative design, guided by phenomenology, examined perceptions of workplace physical activity and perceived levels of engagement, as well as constraints related to involvement among university …

Why Are Parents Choosing Forest Preschool? A Look Into Parent Choice And Outcome Expectations In A Forest Preschool Setting., Victoria M. Jones

Electronic Theses and Dissertations

As interest in alternative early childhood education settings continues to grow, Forest Preschools—programs emphasizing immersive outdoor, nature-based learning—have gained increasing attention from parents across the United States. This qualitative research study explores the underlying motivations and decision-making processes that lead families to choose Forest Preschool settings. Guided by Kurt Lewin’s Field Theory, which examines behavior as a function of person and environment, the study investigates the dynamic interplay of personal beliefs, social influences, and contextual factors that shape parental choice. Specifically, this study addresses four key research questions: (1) How do families who choose Forest Preschools gain information about preschool …

In A Safe-Space Of Her Own: Alice's Journey Through A Traumatized Wonderland To Find Attunement And Recovery, Cheston A. Axton

Electronic Theses and Dissertations

Throughout Alice’s Adventures in Wonderland/Through the Looking-Glass’s 160-year existence, Lewis Carroll’s seven-year-old protagonist has experienced many changes and alterations. With an ever-growing pop culture interest, Alice’s original narrative has undergone numerous adaptations, with each new variation diving deeper into the impact of trauma on Wonderland.

This thesis continues this existing discourse by examining Wonderland’s capacity to facilitate recovery in the aftermath of severe trauma. Through this research, the traumatic experiences of Alice, from Christina Henry’s The Chronicles of Alice: Alice and American McGee’s Alice: Madness Returns, are examined concerning their effect(s) on her construction of Wonderland, as …

A Case Study Of The Perceived Support Needs Of Community College Faculty, Ramona C. Shelton

Electronic Theses and Dissertations

This qualitative case study explored the perceptions of community college faculty members in Tennessee regarding the supports they feel they need to be successful academicians both inside and outside of the classroom. Thirteen faculty members participated in the study, representing the 4 faculty ranking categories at the institution: adjunct/part-time, new full-time, junior/untenured, and senior/tenured. Interviews were semi-structured to allow the participants the opportunity to share their honest experiences on what support needs they have, how those needs have been met, and what support areas they expect to emerge in the future. Four academic administrators also participated in the study in …

The Effects Of Off-Season Evidence-Based Training Block Periodization Program On The Performance Of Soccer Athletes In A Di School: An Exploratory Study, Ibrahim F. Almughathawi

Electronic Theses and Dissertations

The investigators explored the effects of a two-year evidence-based block periodization strength training program on performance outcomes in NCAA Division I male soccer athletes. The investigators aimed to examine longitudinal changes in body composition, explosive strength, and match-play physical demands, as well as the associations between field-based performance assessment and GPS-derived metrics. Using a retrospective design, data were drawn from a research data repository for athletes who participated in a long-term sport science monitoring program under the same head coach and training conditions. Performance measures included vertical jump assessments (static and counter movement jumps under bodyweight and external load), isometric …

Give Me A Break: Exploring The Use Of A Reset Room On Secondary School Students And Resilient Practices In Tennessee, Alex White

Electronic Theses and Dissertations

The culmination of toxic stress and social-emotional instability can result in significant challenges for students. Incorporating an appropriate response to address the social-emotional needs of students must be a priority if schools seek to see improvements in attendance, discipline, and ultimately academic success. Resilient middle and high schools recognized the need to create innovative spaces for students to learn how to self-regulate challenging emotions during the school day. The purpose of this quantitative research study was to investigate the relationship between chronic absenteeism, office disciplinary referrals, and the use of Resilient Schools Reset Rooms in middle and high schools from …

Orchestrated Architecture Dismantling: Borrelia Burgdorferi’S Coordinated Destruction Of Adaptive Immune Responses, Craig A. Land

Electronic Theses and Dissertations

Borrelia burgdorferi represents the most prevalent vector-borne bacteria in North America, affecting ~476,000 Americans annually yet persisting despite robust immune responses. This project reveals spirochetes target adaptive immunity through coordinated lymphatic colonization and precision immune dysregulation.

Using comparative host models (C57BL/6 vs. reservoir Peromyscus leucopus), we demonstrate lymph node colonization within 48-hours, with spirochetes exploiting LYVE-1-positive lymphatic structures as dissemination highways while avoiding the interior of follicular regions. Critically, we identify targeted CD4+ T-cell elimination in germinal center border zones at 21-DPI, precisely when these cells should be coordinating protective immunity. Concurrent upregulation of inhibitory receptor CD32b creates molecular …