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Understanding Emotional Intelligence And Its Relationship To Clinical Reasoning In Nursing Students: A Mixed Methods Study, Heidi M. Meyer

Electronic Theses and Dissertations

Purpose. The purpose of this study was to explore emotional intelligence (EI) and its relationship to clinical reasoning in senior bachelor of science in nursing (BSN) students to gain a better understanding of how emotions are used in clinical learning experiences. This study was guided by the Four Branch Ability Model of EI.
Background. The current complex healthcare environment requires nursing students to be prepared to effectively reason in emotionally charged situations. The concept of EI and its beneficial effects in nursing are becoming more evident in the literature. However, it is still not well understood what the …

A New Lens: Psychological Ownership As An Element To Promoting Organizational Change, Tyler Carlson

Electronic Theses and Dissertations

Much of the change management literature has focused on change from the perspective of the organization as a whole. However, researchers have begun to explore the impact change has on employees, as well as employee perceptions of organizational change. The current study explored the role psychological ownership has in the context of organizational change, by using it is as a moderator between employee openness to organizational change (EOOC), and organizational commitment, job stress, and turnover intentions. Results revealed a significant positive correlation between EOOC and organizational commitment, a significant negative correlation between EOOC and job stress, as well as turnover …

In-Silico Design And Synthesis Of Selective Estrogen Receptor Modulators Targeting Ovarian Cancer, John Apraku

Electronic Theses and Dissertations

The established records of the safety of Ormeloxifene along with its favorable bioavailability and ability to inhibit rapid cell proliferation in the endometrium during embryonic implantation has made it one of the best drug candidates for controlling undesirable rapid cell growth such as endometriosis and cancerous tumor conditions. Recent studies have confirmed the effectiveness of Ormeloxifene to suppress and inhibit epithelial-mesenchymal transition process as evidenced by repression of N-cadherin, slug, snail, vimentin, MMPs, β-catenin/TCF-4 transcriptional activity and induce the expression of pGSK3b. Recently conducted studies have revealed the dynamic binding of ormeloxifene with β-catenin, GSK3b, CDK4, and other downstream EGFR. …

Menstrual Cycle And The Vascular Properties Of Remote Preconditioning, Shelby Rachel

Electronic Theses and Dissertations

PURPOSE: A promising therapeutic intervention to counteract endothelial ischemia/reperfusion (I/R) injury is ischemic preconditioning (IPC). Limited data from ovariectomized animal models shows that estrogen deficiency abolishes the cardioprotective effects of IPC, whereas estrogen replacement restores protection. This suggests that alterations in female sex hormones, particularly estrogens, that occur naturally during the menstrual cycle is likely to influence the vascular protective properties of IPC. The aim of the present study was to identify how changes in female sex hormones that occur naturally during the menstrual cycle interfere with IPC to provide vascular endothelial protection in women. METHODS: Nine healthy premenopausal eumenorrheic …

Level Of Satisfaction Among Food Pantry Clients, Staff/Volunteers, And Directors And Its Association With Client Choice In Food Pantry Layouts, Myranda Dunmire

Electronic Theses and Dissertations

Objectives: Food insecurity is an issue in rural communities, particularly among food pantry clients. Food pantries may not provide clients with the opportunity to choose their own foods (client choice), and instead may just give a set amount and type of foods. Client choice is important in regards to client health status as well as perceptions of autonomy and quality of life. Although client choice can be promoted in food pantries, it may be difficult to grasp the process of food pantry transitioning and how well changes such as these may be perceived by clients or food pantry personnel. We …

A Sustainable Future In The Implementation Of Clinical Pharmacogenomics, Nicholas Keeling

Electronic Theses and Dissertations

Purpose: The sustainability of clinical pharmacogenomics requires further study of clinical education on the topic, its effects on clinical workflow, and the responsibilities of different providers for its delivery. Tools from the discipline of implementation science were utilized herein to help achieve the purposes of the three studies. The broad purpose of this dissertation is to advance the work of clinical pharmacogenomic implementation through a more rigorous convergence with implementation science.

Methods: Three studies constitute the whole of this dissertation. The first is a scoping review that provides a broad characterization of the methods utilized in available peer-revieliterature focusing on …

Continuous Production Of Raloxifene Hydrochloride Loaded Nanostructured Lipid Carriers Using Hot-Melt Extrusion Technology, Derick Muhindo

Electronic Theses and Dissertations

The aim of this study was to utilize a continuous process for the production of Raloxifene Hydrochloride (RX-HCl) loaded NLC formulations for extended drug release using hot-melt extrusion technology coupled with probe sonication, and also to evaluate the in vitro characteristics of the prepared NLCs by particle size, PDI, zeta potential, entrapment efficiency, drug loading, and in vitro drug release profile. Preparation of the NLCs using HME technology involved two main steps, first formation of a pre-emulsion after extrusion and then size reduction of the pre-emulsion using probe sonication to obtain the NLCs. Process parameters for the extrusion process like …

Effect Of Sulfobutyl Ether Β-Cyclodextrins On Oral And Dermal Pharmacokinetics Of Drugs, Vijay Kumar Shankar

Electronic Theses and Dissertations

Silymarin is an extract of Milk Thistle, major constituents are taxifolin, silychristin, silydianin, silybin A, silybin B, isosilybin A and isosilybin B. The in vitro, preclinical and clinical studies have demonstrated silymarin possesses hepatoprotective, anticancer, hypocholesterolemic, cardioprotective effect and dermatological beneficial effect (treatment of UV induced erythema, melanoma, non-melanoma skin cancer, rosacea, melasma, vitiligo and psoriasis) both individually and collectively. Solubility enhancement of silymarin constituent is utmost important to increase bioavailability and to improve drug developability property. The solubility of silymarin in water was enhanced by SBE-β-CD by conventional and heating method, heating method was found to be more efficient …

Écriture Féminine Africaine Au Vingt-Et-Unième Siècle: Une Proposition De Cours De Littérature Africaine Pour Les Étudiants De Master Et Doctorat, Anaïs Louise Siewe Deuga

Electronic Theses and Dissertations

African Literature has been taught in universities of the world for almost 60 years now. Since then, it has evolved tremendously but the syllabi of these courses haven’t really. Most of the texts read during the twentieth century and considered as classics of African literature are still studied today while more recent literary works are ignored by scholars. Moreover, back then, it was considered useless for a girl to receive an education, priority was given to boys instead; as a result there were more educated boys than girls, and thus more male writers than female ones and these few female …

The Role Of Dunc13 In Ethanol Tolerance, Yusuke Wachi

Electronic Theses and Dissertations

Although the effects of ethanol on presynaptic activity have been studied, the molecular mechanisms and the changes in gene expression which are responsible for inducing ethanol tolerance are unclear. Munc13-1 is an active-zone protein that is essential for presynaptic vesicle fusion. This protein interacts with vesicle fusion machinery at presynaptic active zones in the mammalian brain. The C1 domain of Munc13-1 binds diacylglycerol (DAG), which helps membrane localization of this protein and promotes vesicle fusion, facilitating synaptic vesicle release. Previously, it was shown that ethanol binds to the C1 domain of Munc13-1 in vitro at concentrations below 100 mM (Das …

An Exploration Of Relationships Between Parenting Stress And Primary Headache Disorders, Yelena Louise Johnson

Electronic Theses and Dissertations

Stress is the most commonly reported trigger for headache and stress affects headache both directly through resulting physiological changes and indirectly through its effects on lifestyle and coping behaviors. However one form of stress that has been neglected within headache is parenting. Parenting stress is defined as the imbalance between parents’ perceptions of available resources and their perceived demands of parenthood. Many variables have been established as predictors of parenting stress (e.g. demographic variables child behavior maternal depression) though fewer studies have examined its effects on health. Given that headache and parenthood share similar demographic distributions and risk factors exploration …

Petrology, Provenance, And Depositional Setting Of The Lower Tallahatta Formation (Meridian Sand) In Grenada County, Mississippi, Husamaldeen Zubi

Electronic Theses and Dissertations

The Meridian Sand represents the lowermost member of the Middle Eocene Tallahatta Formation, which is found in the Gulf Coast region of the United States. Five stratigraphic sections in Grenada County were measured and described. Twenty-one sand and sandstone samples, and 2 mud samples were collected from all sections. Textural analyses were performed on all 23 samples to determine their lithologic properties. Petrographic descriptions and modal analyses were performed on thin sections made from the 21 sand and sandstone samples, and 400 grains were point counted in each sample. Geochemical analyses were carried out on all sand, sandstone, and mud …

The Doubting Chain, Eric Delp

Electronic Theses and Dissertations

This is a collection of poetry.

Acute Exercise And Creativity: Embodied Cognition Approaches, Emily M. Frith

Electronic Theses and Dissertations

This dissertation manuscript is the culmination of three years of research examining several unique, exercise-induced mechanisms underlying creativity. This collection of work addresses historical and current empirical concepts of creativity in a narrative review, providing recommendations for future research. Several reviews follow this introduction, highlighting the proposed effects of exercise on creativity, putative mechanisms for creativity, and the effects of exercise and embodied manipulations on creative behavior. Multiple experiments utilizing moderate-intensity exercise as a theoretical stimulus for higher-order cognitions were conducted to investigate associations between exercise and creativity, which lead to the final dissertation experiment. The dissertation experiment was the …

Improving Literacy Rates For Students With Dyslexia In A Rural School District, Steven William Havens

Electronic Theses and Dissertations

This applied research study aimed to improve literacy rates for students identified as having dyslexic tendencies in the Lynn County School District. The need to improve literacy rates of students with dyslexia in the Reaching Reading Success Program was identified through Mississippi K-3 Assessment Support System data. Using the two elements found in the program evaluation, accurate identification of dyslexic students and multisensory interventions the study sought to improve the literacy rates for students with dyslexia in kindergarten. Assessment, survey, and interview data were used in this applied research study to determine success. The findings indicated early identification, multi-sensory remediation, …

Geothermal Resource Assessment Of Mississippi, Adam Blake Goodwin

Electronic Theses and Dissertations

Geothermal energy is exploited through the process of using hot water or steam extracted from reservoirs of geothermal heat in Earth's crust which is derived from the upward convection and conduction of heat from Earth’s mantle and core. This energy can be harnessed to power geothermal heat pumps, heat water, or to generate electricity. Previous geothermal assessments of Mississippi have been locally focused, either in the southern Mississippi River flood plains or in eastern north central Mississippi at an active lignite coal mine. The focus of this project was to calculate and map heat flow estimates within the entire state …

Developing Zebrafish As An In Vivo Model To Screen Compounds For Anti-Cancer Activity In Human Breast Cancer, Trisha Dhawan

Electronic Theses and Dissertations

Breast Cancer (BC) is the most frequently diagnosed cancer; 1:8 women are at risk of developing BC in her lifetime. Cancer metastasis causes the majority of deaths in BC patients. Moreover, side effects of traditional chemotherapeutic drugs (TCD) impair the quality of life of these patients. Discovery and development of safe and effective new therapies is imperative for the treatment of BC and targeting metastasis. The goal herein is to further expand the applicability of in vivo xenotransplantation of human BC cells in transgenic zebrafish to screen potential chemotherapeutics for toxicity and efficacy. For xenotransplantation, MCF-7, BT-474, and MDA-MB-231 BC …

Activist Modernisms: Human Rights And Anti-Totalitarianism In Mid-Twentieth Century Literature, Mary Ellen Gray

Electronic Theses and Dissertations

The period after World War II saw the emergence of a new discourse of human rights, with the signing of the 1948 Universal Declaration of Human Rights. In the postwar period and throughout the twentieth century, human rights would often be vieas a set of self-evident, monolithic, and timeless values that had merely reached their full realization after the horrors of the war. This study examines a body of literature from the 1930s and 40s, the wartime moment just before the foundation of the twentieth century universal rights ideology, to explore the process by which theories of human rights are …

Near-Infrared High Efficiency Organic Dye Sensitized Solar Cells (Dscs) And Biological Fluorescent Imaging Dyes, Yanbing Zhang

Electronic Theses and Dissertations

With the energy consumption increase every year, the non-renewable energy sources such as fossil fuels, natural gas, and coal will not sustain forever. In this case, searching for a way to develop a renewable energy source is an emergency. For decades, dye-sensitized solar cells (DSCs) have received intensive attention due to their high power conversion efficiency and low material cost. This dissertation describes efforts to design and synthesize near-infrared organic dyes to apply to two systems: first, for use in the improvement of DSCs by the optimization of electron rich components such as ullazine and cross-conjugated -bridges to increase photon-to-electricity …

Organic Sensitizers For High Efficiency Dye-Sensitized Solar Cells, Adithya Peddapuram

Electronic Theses and Dissertations

After the industrial revolution in 19th-century energy, demand has increased exponentially. Relying on fossil fuels long term is not a good option due to their non-renewable nature and concerns about burning fossil fuels raising carbon dioxide levels in atmosphere. This dissertation describes, utilizing sunlight for electricity production with dye-sensitized solar cells (DSCs). DSCs are an attractive solar technology due to processing advantages over traditional solar cells. To improve the stability of DSCs, strong surface binding dyes are important. This work studies the dual anchor dual donor (DD-π-AA) dye framework with various donors (electron rich π-systems) and π-bridges (electron neutral π-systems). …

Acoustic Radiation Force On A Fluid To Fluid Boundary By Phase Plate Focused Ultrasound, Robert Lee Lirette

Electronic Theses and Dissertations

In this study, the physics and applications of the ultrasonic radiation force at the interface between two immiscible fluids were investigated. These studies were performed using low-profile discrete-stepped lenses to the modify the phase of the incident radiation generating multiple field morphologies. In its first application to acoustics, a fraxicon lens was developed to approximate the field generated by an axicon. This type of lens creates a minimally diffractive Bessel beam and long depth of focus that is useful in ultrasonic imaging, therapy, and non-destructive evaluation techniques. Fields modified by fraxicon, Fresnel, and axicon lenses were characterized experimentally by scanning …

Weight Teasing Among Obese Youth: Social Functioning Outcomes Following A Pediatric Weight Management Intervention, Joseph Mitchell Magness

Electronic Theses and Dissertations

The prevalence of excess weight and obesity among children and adolescents in the United States continues to increase. Aside from the different effects weight has on a person’s physical and psychological well-being, obese youth often experience poorer social functioning than normal weight peers. Weight teasing is among those highlighted social difficulties. Pediatric weight management program interventions have been shown to improve health-related quality of life (HRQoL) across domains for obese youth. However, few studies have examined the impact of weight management interventions on social quality of life for those with a history of weight teasing. The present study aimed to …

Generalized Radial Transport Model For Interpreting Convergent Flow Tracer Tests In Fractured Rock, Md Lal Mamud

Electronic Theses and Dissertations

The double-porosity Generalized Radial Transport (GRT) model is an extension of the generalized radial flow approach developed for hydraulic test interpretation. In both approaches, a flow dimension characterizes the change in flow area versus radial distance from the borehole. The GRT model collapses to a 1D, radial, and spherical advection dispersion equation (ADE) for integer flow dimensions of 1, 2, and 3, respectively. And, the model also transforms to sub-linear, sub-radial, sub-spherical and eventually transform to super-spherical transport model for non-integer flow dimension, n of 0 < n < 1, 1 < n < 2, 2 < n < 3 and n >3 respectively. Non-integer flow dimensions, especially sub-radial, are commonly reported from pumping tests in …

Pegylated Nanostructured Lipid Carries For Amphotericin B Ocular Delivery, Prit Manish Lakhani

Electronic Theses and Dissertations

The Chapter II focuses on formulation of an optimized and robust amphotericin B ocular formulation with prolonged precorneal residence and ocular tissue concentration at par or superior to the marketed preparations. Additionally, demonstrating stability of amphotericin B formulations in presence of preservative in comparison to marketed preparation, making it an ideal choice of formulation for multi-dosing. As mentioned earlier, we optimized PEGylated nanostructured lipid carriers (PEG-NLC-AmB) for ocular delivery of amphotericin B. The formulations could be autoclaved with at least one-month stability and in vivo ocular biodistribution was statistically insignificantly different compared to AmBisome®. To accomplish the aim, strategies such …

Whistle Before You Work: Defining Paid Labor In The New Deal State, 1938-1947, Thomas Porter

Electronic Theses and Dissertations

This thesis traces the conceptualization of work from the passage of the 1938 Fair Labor Standards Act (FLSA) through the Portal-To-Portal Pay Act of 1947. I argue that the FLSA created a new framework for industrial laborers to define what constituted work. This enables an understanding of work as defined by those in mines and on the industrial plants floor, allowing those who were closest to toil and exertion to create their own definitions. By 1946, Congress heeded to the complaints of the military and capitalists and codified their definition of work and the work week. This restricted the broadly …

Effect Of Solvent Interaction & Soluble Microneedles On Skin Permeability To Drug Molecules, Abhijeet Maurya

Electronic Theses and Dissertations

Skin forms a formidable barrier protecting the human body from external environmental rigors and excessive loss of water; maintaining equilibrium. The barrier properties of the skin can be attributed to its unique macromolecular organization and morphology. As a route for drug administration, skin presents a large surface area and can be used for both systemic and localized targeted drug delivery applications offering several advantages over conventional drug therapy; avoidance of first pass metabolism, patient compliance, sustained or controlled delivery for an extended period, to name a few. However, the organized structure of the skin, since intended to prevent entry of …

Two Way Street: An Applied Research Study On The Effects Of Increased Parent And Community Involvement Activities On Student Academic Growth In Mathematics At South Lee Middle School, Jason Clifton Arledge

Electronic Theses and Dissertations

The purpose of this study was two-fold. The first overarching goal was to increase student academic growth on the Mississippi Academic Assessment Program mathematics assessment to at least 75%. This was attempted through implementation of grade-level Remind services and the Red Raider Family program. The second overarching goal was to create a cycle of continuous improvement through feedback from key stakeholders in the form of surveys, interviews, focus groups, document analysis, and descriptive statistics. South Lee Middle School evaluated each of these initiatives and utilized resources to adjust these programs for use in the 2018-2019 school year.

Three Essays On Corporate Bonds Issuance And Trading, Violetta Y. Davydenko

Electronic Theses and Dissertations

We explore the bond “clustering” phenomenon, using a sample of bond issuances in 2000-2015. Bond “clustering” is when the number of bonds issued that year exceeds three standard deviations above the mean number of issues for the firm over the sample period. We examine why firms opt for multiple issuances instead of a large one: exhaustion of debt capacity, refunding existing debt, timing favorable market conditions, managing working capital or financing profitable investment opportunities. Results indicate that firms do not cluster due to simply refinancing outstanding debt, but in order to manage their liquidity position and short-tern cash needs, to …

A Numerical Study Of Granular Dam-Break Flows, Nuttita Pophet

Electronic Theses and Dissertations

Granular flows are mass movements of mixtures of solid particles and interstitial fluid. Examples include landslides, debris flows and tailings dam-break flows. These types of flows are often catastrophic events, and cover a wide range of phenomena of interest to both scientists and engineers. The mechanical properties of granular materials and the hydraulic behavior of the flows originate from solid and fluid phases, their distribution and interaction. Understanding the behavior of these types of flows and developing reliable predictive models are important.

Mac-Phy Frameworks For Lte And Wifi Networks' Coexistence Over The Unlicensed Band, Hadi Ahmad Kasasbeh

Electronic Theses and Dissertations

The main focus of this dissertation is to address these issues and to analyze the interactions between LTE and WiFi coexisting on the unlicensed spectrum. This can be done by providing some improvements in the first two communication layers in both technologies. Regarding the physical (PHY) layer, efficient spectrum sensing and data fusion techniques that consider correlated spectrum sensing readings at the LTE/WiFi users (sensors) are needed. Failure to consider such correlation has been a major shortcoming of the literature. This resulted in poorly performing spectrum sensing systems if such correlation is not considered in correlated-measurements environments.