Digital Commons Network^™

All Season Heat Pipe System., Adrienne Marie Parsons

Electronic Theses and Dissertations

Our energy choices impact the earth’s natural systems and climate. As this becomes increasingly important, the need for decreasing our energy usage is essential. Conventional passive solar systems can significantly reduce the heating load. Similarly, passive ambient energy systems, such as ventilation and sky radiation, can reduce cooling loads. However, the integration of passive heating and cooling systems in the same building and the benefits of actively controlling these otherwise passive systems to maximize annual energy savings has largely been unexplored. This study first evaluates the building cooling capacity of sky radiation, which was previously identified to have the greatest …

Exploring Individual And Dyadic Associations Of Dispositional Mindfulness As An Ameliorative Factor Of Anxiety And Roommate Satisfaction Among Undergraduate Roommates., Kala Phillips

Electronic Theses and Dissertations

For many young adults, the college experience is stressful and the adjustment to college life can present many unique challenges. Up to one-half of undergraduates report anxiety, with prevalence rates that appear to be on the rise. Social transitions, such as living with a roommate, can also present challenges. The current study explored dispositional mindfulness, a capacity for attending to present-moment experiences, as a potential ameliorative factor of anxiety and roommate satisfaction. Dyadic associations of dispositional mindfulness were also explored among roommate dyads. Fifty undergraduate roommate dyads (N=100) provided self-report measures of demographics, dispositional mindfulness, anxiety, and three facets of …

Characterization Of A More Clinically Relevant Human Leukemia Xenograft Model To Examine Perturbation Of Met/Sam Metabolism As A Novel Therapeutic Paradigm For Mll-R Leukemia In Vivo., Aditya Barve

Electronic Theses and Dissertations

Acute myeloid leukemia (AML), is a heterogeneous clonal disorder characterized by an accumulation of malignant myeloid progenitors in the bone marrow (BM), hindering normal hematopoiesis. AML exhibits dramatic heterogeneity in terms of cytogenetics, morphology, and chemotherapeutic sensitivity. Therefore, the investigation of novel, efficacious AML therapeutics will require advanced preclinical in vivo model systems, capable of recapitulating patient specific disease heterogeneity, and induction chemotherapy outcomes. A major focus and eventual outcome of this work was the establishment and development of a more clinically relevant mouse xenograft model of patient AML, that efficiently harbors patient derived xenografts (PDXs), and unlike more prevalent …

Disordered Eating, Depression, And Cognitive Vulnerabilities In College Women., Kelsea Visalli

Electronic Theses and Dissertations

This study tests a path model of disordered eating and symptoms of depression derived from the Hopelessness Theory of Depression (Abramson, Metalsky, & Alloy, 1989). The model proposes that cognitive vulnerabilities to depression will be associated with disordered eating behaviors and symptoms of depression in college women. A sample of undergraduate women (n = 181) completed self-report measures assessing disordered eating symptoms and symptoms of depression. Findings revealed that one, but not all, cognitive vulnerability was associated with disordered eating behavior, and that disordered eating behaviors and symptoms of depression are bi-directionally associated. Implications and future research directions are discussed.

Emotion Regulation Is Associated With Peer Victimization Among Children With Attention-Deficit/Hyperactivity Disorder., Nicholas D. Fogleman

Electronic Theses and Dissertations

Background: Children with Attention-Deficit/Hyperactivity Disorder (ADHD) experience higher rates of peer victimization relative to unaffected peers; however, debate remains as to whether core symptoms of ADHD—inattention, hyperactivity and impulsivity—are responsible for increased rates of peer victimization among children with ADHD. Given emotion regulation deficits co-occur among children with ADHD, and are often associated with increased peer victimization experiences, the current study examined the role of emotion regulation in peer victimization among children with ADHD. Methods: Forty-nine children (ages 10-15 years) diagnosed with ADHD and their parents completed measures of emotion regulation and peer victimization. Children also completed a laboratory-based peer …

Predictors Of Empirically-Supported Interventions Following Structured Functional Assessment., Alton Nathaniel Verbist

Electronic Theses and Dissertations

Assessment is foundational to the process of evidence-based practice yet has received little research attention. Project SAFESPACE has recently initiated screening and assessment for all children entering out of home care in Kentucky with the goal of providing assessment-driven, evidence-based treatment. The Child and Adolescent Needs and Strengths (CANS) assessment—the instrument adopted in this service system—is designed to link the assessment process with the selection of appropriate interventions. Informed by naturalistic decision making, this dissertation sought to investigate the relationship between responses on the CANS assessment and the empirically supported interventions subsequently prescribed by the assessing clinician. Using secondary data …

Novel Bayesian Methodology In Multivariate Problems., Debamita Kundu

Electronic Theses and Dissertations

This dissertation involves developing novel Bayesian methodology for multivariate problems. In particular, it focuses on two contexts: shrinkage based variable selection in multivariate regression and simultaneous covariance estimation of multiple groups. Both these projects are centered around fully Bayesian inference schemes based on hierarchical modeling to capture context-specific features of the data and the development of computationally efficient estimation algorithm. Variable selection over a potentially large set of covariates in a linear model is quite popular. In the Bayesian context, common prior choices can lead to a posterior expectation of the regression coefficients that is a sparse (or nearly sparse) …

A Study Of Big Field Multivariate Cryptography., Ryann Cartor

Electronic Theses and Dissertations

As the world grapples with the possibility of widespread quantum computing, the cryptosystems of the day need to be up to date. Multivariate Public Key Cryptography is a leading option for security in a post quantum society. One goal of this work is to classify the security of multivariate schemes, especially C*variants. We begin by introducing Multivariate Public Key Cryptography and will then discuss different multivariate schemes and the main types of attacks that have been proven effective against multivariate schemes. Once we have developed an appropriate background, we analyze security of different schemes against particular attacks. Specifically, we …

Queering Black Greek-Lettered Fraternities, Masculinity And Manhood : A Queer Of Color Critique Of Institutionality In Higher Education., Antron Demel Mahoney

Electronic Theses and Dissertations

Drawing heavily on Roderick Ferguson’s (2012) theory of institutionality, this dissertation constructs a counter-historical genealogy of racialized gender in higher education and U.S. society through the formation of black Greek-lettered fraternities. Ferguson argues that with the insurgence of minority resistance globally and domestically during the mid-twentieth century, hegemonic power took a new form. Instead of rejecting minority difference, power’s new network attempted to work through and with minority difference in an effort to absorb and restrict these radical formations within state, capital and academy frameworks—producing narrow or one-dimensional minority subjectivities. Established at the turn of the twentieth century, black Greek-lettered …

The Conceptualization Of The Positive Cognitive Triad And Associations With Depressive Symptoms In Adolescents., Caroline M. Pittard

Electronic Theses and Dissertations

Depressive symptoms during adolescence have been found to be associated with negative outcomes such as decreased academic performance, absenteeism, substance abuse, and poor physical health. The positive cognitive triad has been considered to be a protective factor against adolescent depressive symptoms. The positive cognitive triad is made up of three subfactors of cognitions, specifically, positive cognitions about the self, the world, and the future. This dissertation examined the various conceptualizations of the positive cognitive triad and their relation to depressive symptoms. These conceptualizations included considering the positive cognitive triad as a single overall protective factor (additive model), as multiple possible …

Improving Flow-Induced Hemolysis Prediction Models., Mohammad Mohaghegh Faghih

Electronic Theses and Dissertations

Partial or complete failure of red blood cell membrane, also known as hemolysis, is a persistent issue with almost all blood contacting devices. Many experimental and theoretical contributions over the last few decades have increased insight into the mechanisms of mechanical hemolysis in both laminar and turbulent flow regimes, with the ultimate goal of developing a comprehensive, mechanistic and universal hemolysis prediction model. My research is broadly divided into two sections: theoretical/analytical/Computational Fluid Dynamics (CFD) analyses and experimental tests. The first part of my research revolved entirely around analyzing the simplest and most popular hemolysis model, commonly called as the …

Determining The Effect Of An Educational Intervention On Medical Support Personnel's Knowledge To Administer A Standardized Developmental Screening Tool., Leslie Chiaventone Lopez

Electronic Theses and Dissertations

Early treatment of developmental delays leads to improved outcomes for children (Yeung et al., 2014). In order to benefit from early intervention, children with developmental delays must be identified and referred at a young age. Although the use of validated developmental screening tools is supported by American Academy of Pediatrics (AAP) guidelines, these instruments are used variably by general physicians in pediatric practice (King et al., 2010). Because of the expanding work roles of medical support personnel, it is worthwhile to determine if this group can administer and score a developmental screening tool after completing an educational intervention to assist …

Allee Effects Introduced By Density Dependent Phenology., Timothy James Pervenecki

Electronic Theses and Dissertations

We consider both the nonspatial model and spatial model of a species that gives birth to eggs at the end of the year. It is assumed that the timing of emergence from eggs is controled by phenology, which is density dependent. In general, the solution maps for our models are implicit; When the solution map is explicit, it is extremely complex and it is easier to work with the implicit map. We derive integral conditions for which the nonspatial model exhibits strong Allee effect. We also provide a necessary condition and a sufficient condition for the existence of positive equilibrium …

Algebraic Properties Of Neural Codes., Katie C. Christensen

Electronic Theses and Dissertations

The neural rings and ideals as algebraic tools for analyzing the intrinsic structure of neural codes were introduced by C. Curto, V. Itskov, A. Veliz-Cuba, and N. Youngs in 2013. Since then they have been investigated in several papers, including the 2017 paper by S. G\"unt\"urk\"un, J. Jeffries, and J. Sun, in which the notion of polarization of neural ideals was introduced. We extend their ideas by introducing the polarization of motifs and neural codes, and show that these notions have very nice properties which allow the studying of the intrinsic structure of neural codes of length $n$ via the …

Religious Coping Measurement In The Context Of Long-Term Care., Nathaniel David Andrew

Electronic Theses and Dissertations

This dissertation explores the reliability and validity of religious coping measures in long-term care settings. The paper begins with a discussion of general coping and religious coping theory, coping measurement, and a review of religious coping in elderly long-term care residents. Next, a modified model of coping and resilience in older adults is introduced. The latter part of the paper describes a study that examines the reliability and validity of two specific religious coping measures in nursing home, assisted living, and personal care residents. The study utilizes a cross-sectional design by interviewing a convenience sample of nursing home, assisted living, …

Character Arcs: Mapping Creative Writers' Trajectories Into The Composition Classroom., Jon Udelson

Electronic Theses and Dissertations

This dissertation develops a theoretical and empirical approach to the study of professional creative writers and teachers. Specifically, it examines how these writers developed their knowledge of creative writing and writing pedagogy and how that knowledge informs their work as instructors of composition. Despite the common practice across writing programs of hiring formally-trained creative writers (M.A., M.F.A, Ph.D.) to teach first-year composition and related courses, little scholarship in the field of rhetoric and composition or writing studies more broadly specifically focuses on the disciplinary and professional development of these writer-teachers. Through case studies of graduate students, contingent faculty, lecturers, and …

Sensemaking In The Process Of Inquiry: A Qualitative Case Study Of A Networked Improvement Community, Bethany Fillers

Electronic Theses and Dissertations

There are persistent and pervasive issues plaguing American education, and almost seventy years of educational reform efforts have failed to adequately improve educational outcomes for many of America’s children. Networked improvement communities (or NICs) are a type of social organization created to address such problems and are proposed as an effective and efficient way to organize improvement efforts. The purpose of this qualitative case study was to explore the sensemaking experience of a newly-formed networked improvement community as members engaged in inquiry around a chosen problem of practice. During network initiation, NIC members engage in experiences to collaboratively identify and …

Exploring The Match Demands Of Division I Women’S Collegiate Soccer, Robert W. Sausaman

Electronic Theses and Dissertations

The purpose of this dissertation is to shed light on the physical demands of women’s soccer at the NCAA division I college level. Though research does exists describing the physical demands of women’s soccer, the vast majority seeks to explain the physical demands association with the professional and international level. This dissertation sought to: 1) examine the physical demands of NCAA division I women’s soccer and 2) observe changes in physical demands of two NCAA division I women’s soccer players over a four-year career using a case study approach.

Study 1 examined the physical demands of twenty-three athlete from a …

Predicting Residency Match Outcomes For Fourth-Year Medical Students., Jacob Shreffler

Electronic Theses and Dissertations

An important goal for undergraduate medical education program leaders is to prepare their medical students to successfully match during the National Residency Match Program (Gauer & Jackson, 2017). Due to the recent increase in applications submitted during the residency process, it is critical for medical education programs to better understand the factors and attributes of those medical students who are successfully matching (Liang, Curtin, Signer, & Sawoia, 2017). As there is a larger number of medical students now enrolled than positions available for residency, the number of unmatched seniors is expected to rise (Bumsted, Schenider, & Deiorio, 2017). Additionally, the …

Leonora Carrington : A Bestiary., Stephanie Wise

Electronic Theses and Dissertations

Similar to the painted creatures that dwell within the illuminated manuscripts of ancient and medieval bestiaries, the beasts in Leonora Carrington’s early work are used metaphorically. She was deeply influenced in her formative years by mythology and animals; tales with heraldic characters, obscure adventures, and symbolic meanings were foundational to her works. World War II and a subsequent internment in a sanitorium initiated Carrington to wrestle with an existential crisis. Her capacity and appetite for sources of inspiration and knowledge was boundless; infinite symbolic references were readily available for her artistic executions. The metaphors adapted or created by Carrington enabled …

Cognitive Satellite Communications And Representation Learning For Streaming And Complex Graphs., Wenqi Liu

Electronic Theses and Dissertations

This dissertation includes two topics. The first topic studies a promising dynamic spectrum access algorithm (DSA) that improves the throughput of satellite communication (SATCOM) under the uncertainty. The other topic investigates distributed representation learning for streaming and complex networks. DSA allows a secondary user to access the spectrum that are not occupied by primary users. However, uncertainty in SATCOM causes more spectrum sensing errors. In this dissertation, the uncertainty has been addressed by formulating a DSA decision-making process as a Partially Observable Markov Decision Process (POMDP) model to optimally determine which channels to sense and access. Large-scale networks have attracted …

Affirmatively Furthering Fair Housing At The Local Level : A Critical Discourse Analysis Of Practices In Louisville, Kentucky., Steven P. Sizemore

Electronic Theses and Dissertations

This qualitative research project is an immersion into the beliefs, ideas, meanings, values, and feelings of actors engaged in shaping local housing policies. The dissertation examines how discourse constitutes and shapes the knowledge of policy actors engaged in fair housing policies and practices in Louisville, Kentucky. I argue that policy discourse is the site where social problems become framed, bounded, and transformed into action. Therefore, if the objective of the Fair Housing Act’s mandate for HUD and its recipients is to operate programs in a manner that “affirmatively furthers fair housing” (AFFH), it is essential to understand the discursive acts …

Characterizing Majority Rule On Various Discrete Models Of Consensus., Trevor Leach

Electronic Theses and Dissertations

In any social structure, there is often a need to reach decisions, not only within a group but between groups as well, sometimes even urgently so. Each of the individuals constituting these groups has their own preference for the decision to be made. We will discuss the problem of aggregating individual preferences into a collective preference and under what conditions we are required to select a collective majority. In this dissertation we will look at three models of consensus and show the conditions vary based on the model.

Does Thermotolerance In Daphnia Depend On The Mitochondrial Function?, Rajib Hasan

Electronic Theses and Dissertations

Thermotolerance limit in aquatic organism is set by the ability to sustain aerobic scope to sudden temperature shifts. This study tested the genetic and plastic differences in thermotolerance of Daphnia that can be explained by the differences in the ability to retain mitochondrial integrity at high temperatures. Five genotypes with different biogeographic origins were acclimated to 18^ᵒC and 25^ᵒC. We developed a rhodamine 123 in-vivo assay to measure mitochondrial membrane potential and observed higher fluorescent in heat damaged tissues as the disruption of the mitochondrial membrane potential. Significant effects on temperature tolerance were observed with CCCP …

Triple-Junction Solar Cells : In Parallel., Levi C Mays

Electronic Theses and Dissertations

This paper looks into the current inefficiency of solar cells and attempts a few alternative solar cell structures in order to provide a more effective source of renewable energy. Currently, multi-junction solar cells are being developed to capture the sun’s light more efficiently. One of the ideas in this paper is to add a window to see if the addition of such a layer into a junction will increase the voltage while maintaining nearly the same current output. Central to this paper is the rearranging of the conducting layers of the multi-junction cell so that the junctions can be connected …

Non-Viral Transfection Efficiencies For The Advancement Of Car-T Therapy., Emily M Murphy

Electronic Theses and Dissertations

Leukemias are the most common form of childhood cancer making up 30% of total pediatric oncological cases, and Acute Lymphoblastic Leukemia (ALL) makes up a significant portion (12%) of the total pediatric cancer diagnoses. In 2017, the FDA approved a successful immunotherapy called CAR-T therapy for the treatment of pediatric B-cell ALL. This therapy includes a CAR (chimeric antigen receptor) that is loaded into the T-cell and expressed. Currently, the loading of the CAR utilizes viral transduction, but consistency issues lead to adverse symptoms in the patients. Better methods of transduction/transfection are being studied in order to improve these consistency …

Purification Of Biomass Hydrolyzates For The Promotion Of Xylose Diester Formation, Laura Fernandez

Electronic Theses and Dissertations

The application of a novel xylose isolation procedure using phenyl boronic acid esterification has been limited to the hydrolyzates of low extractive biomasses like hardwoods and agricultural resides. Hydrolyzates with lower sugar and higher extractive concentrations, like softwoods, have not yielded xylose, or even xylose diester (XDE), the first intermediate product in the new process, under the same conditions. This research applied evaporation concentration, adsorbent separation and membrane filtration to these lower performing biomass hydrolyzates to maximize the yield of the XDE formation step of the new xylose extraction process. Lab-scale tests of these techniques were applied to pine hydrolyzate …

Fluid Flow Analysis Of Diluted Evaporating American Whiskey Droplets., Martin J. Brown Vi

Electronic Theses and Dissertations

The recent discovery of the unique structures, whiskey webs, formed when the evaporation of diluted American whiskey, has raised many questions as to the nature of the structures. Their formation process follows as such: (1) dilution of the whiskey to form nanoaggregates, (2) formation of a monolayer at the air-liquid interface, (3) chaotic ethanol evaporation caused monolayer collapse (via dynamic pressure), (4) bulk fluid evaporation caused monolayer collapse (via reduction of surface area), where the web-like structures reside on the surface, and finally, (5) web-like structures deposit on the substrate. The webs imaged via SEM had a striking resemblance to …

Synthesis, Characterization And Biological Evaluation Of Novel (S,E)-11-[2-(Arylmethylene) Hydrazono] Pyrrolo [2,1-C] [1,4] Benzodiazepine Derivatives, David Mingle

Electronic Theses and Dissertations

Pyrrolo [2,1-c] [1,4] benzodiazepine (PBD) is a class of natural products obtained from various actinomycetes which have both anti-tumor and antibiotic activities and can bind to specific sequences of DNA. PBD-dilactam was initially produced using isatoic anhydride and (L)-proline which was then converted to the PBD-thiolactam using Lawesson's reagent. Reaction of thiolactam with hydrazine in ethanol afforded PBD-11-hydrazinyl. Condensation of 11-hydrazinyl PBD with aldehydes possessing various substitutions was performed to obtain (S,E)-11-[2-(arylmethylene) hydrazono] pyrrolo [2,1-c] [1,4] benzodiazepine derivatives. ¹HNMR, ¹³C-NMR, DEPT, IR, GC-MS and X-ray crystallography were used for the characterization. Inhibition activity of the products …

A Comparison Of Academic Success For Military Associated Students To The General Student Population At Middle Tennessee Community Colleges, Kenneth Hanson

Electronic Theses and Dissertations

Research in military veterans’ transition from military service to civilian college indicates that veterans can be successful in college. Considering veterans are generally older than the average traditional student population who attends college after high school, military veterans fit the characteristics of an adult student. Research indicates that the military veteran may be more disciplined and characteristically achieve their academic goals. However the literature is limited in the research of military veteran success in community colleges, and research is inconsistent with regards to the academic success of military veterans. The military veteran population in the present research consisted of 40 …