Digital Commons Network^™

Rocs: Robust Circular Seriation By Perturbation Entropy Minimization, Carla Rego

Electronic Theses and Dissertations

Identifying and creating patterns enables humans to fulfill their fundamental desire to make sense of things. At the center of this endeavor, seriation is a process of arranging objects to reveal regularities in their characteristics. We present a method to arrange objects cyclically to achieve orderliness based on a novel concept of perturbation entropy, which models the randomness of a sequence under local perturbations on the ordering. We derive a sharp upper bound on the perturbation entropy and develop an algorithm to search for an ordering that minimizes the upper bound. Connections with the traveling salesman problem and the quadratic …

Evaluation Of Feed Additives And Delivery Method For Receiving And Finishing Cattle, Thiago Lauro Maia Ribeiro

Electronic Theses and Dissertations

Trace minerals (TM) and vitamins are essential to improve production output and efficiency in beef cattle. The first experiment was conducted to investigate if the delivery method of TM and Saccharomyces cerevisiae yeast culture influence growth performance and hepatic TM content of receiving steers. The second experiment evaluated the effect of supplemental protected B - vitamins to finishing steers. Experiment 1 used Charolais x Angus steers calves (n = 192; 256 ± 14 kg) in a 49-d receiving experiment. Within 36h of weaning, steers were weighed, allotted to 24 pens (n = 8 steers/pen; 8 pens/treatment) and randomly assigned to …

In-Vivo Assessment Of A Direct-Fed Microbial On Lactation Performances, Blood Biomarkers, Ruminal Fermentation And Microbial Abundance In Transition To Mid-Lactation Holstein Cows, Marcela Bulnes Lopez

Electronic Theses and Dissertations

The transition period is a crucial stage in the lactation cycle and can lead to significant metabolic changes in cows. The use of nutritional interventions, such as direct-fed microbials, may assist cows during the transition from pregnancy to early lactation, reducing the occurrence of metabolic disorders and improving overall health. The primary goal of this study was to assess the effects of a commercial rumen-derived directfed microbial (DFM) product (Galaxis™ Frontier (GF) Native Microbials Inc., CA, USA) on various factors such as performance, blood biomarkers, rumen fermentation, and bacterial population in dairy cows during the transition period up to 100 …

Farmers’ Preference And Willingness To Accept Carbon Payment Programs: Evidence From South Dakota, Pramisha Thapaliya

Electronic Theses and Dissertations

Reducing greenhouse gas (GHG) emissions is crucial to mitigate the impacts of climate change. Agricultural soil carbon sequestration holds great potential in reducing GHG emissions. No-till, conservation till and cover crops are some of the widely recognized carbon-sequestering agricultural conservation practices. However, farmers need to adopt these carbon-sequestering practices to realize the potential of agricultural soil carbon sequestration. Carbon payment or market programs are voluntary mechanisms that could incentivize farmers’ adoption of conservation practices that sequester carbon. However, there is limited knowledge of farmers’ preferences and willingness to accept (WTA) carbon payments for enrollment in such programs. This study investigates …

Stem And Pre-Health Students’ Diminishing Online Conversation Volume Regarding Majors And Careers Within The Field: Why Higher Education Should Care, Susan Roh

Electronic Theses and Dissertations

The purpose of this study was to determine the STEM and pre-health online mention volume change regarding STEM and pre-health majors, careers, and universities, with the data collection period encompassing August of 2018 through June of 2021. We evaluated if the mention sentiment shifted between academic year periods. The data gathered for this study was procured in collaboration with Campus Sonar and the social-listening tool of Brandwatch, which allowed for specifications of the data collected. Kruskal-Wallis tests were used to determine the means of the majors, careers, and universities mentions and mean sentiment volumes. Changes in not only online conversation …

Development Of Novel Cellular Assay Model And Therapeutic Deep Eutectic Solvents To Optimize The Activity Of Anticancer Agents, Nizam Uddin

Electronic Theses and Dissertations

Multidrug resistance (MDR) is the major burden behind chemotherapeutic treatment failure. It is the principal mechanism by which cancer cells evade chemotherapeutic treatment. As a result, aggressive cancer cells survive and continue uncontrolled cell division. Multidrug resistance affects survival rate of almost all types of cancer patients and death toll rises at an alarming rate. There are seven different mechanisms for evolving MDR. The most common mechanism in efflux activity of overexpressed ABC transporters. MRP1 is a prominent ABC transporter that pumps out a wide variety of anticancer drugs from the cells and thereby reduces intracellular drug concentrations and develops …

Design, Synthesis, And Biological Evaluation Of Novel Steroidal Analogs: Potential Anticancer Agents, Trevor Ostlund

Electronic Theses and Dissertations

Cancer is a malicious disease with low survivability rates primarily due to lack of reliable treatment options. Treatments are often non-specific for patients, and cancer resistance to treatment is becoming more prevalent as fast as new therapies are created. Previous studies in our laboratory have focused on the Epidermal Growth Factor Receptor (EGFR) and its downstream kinase family members as a key target for cancer. This cascade controls cell proliferation, anti-apoptotic effects, cell regulation, and other survival factors. Additionally, ABC transporters, responsible for efflux of chemotherapeutic material from cells, are key targets to combat drug resistance. We first evaluated a …

Physically Adjusted Neutral Detergent Fiber System: Effects Of Dextrose And Non-Forage Fiber On Performance, Feeding Behavior, Digestibility, Rumen Fermentation And Rumen Bacterial Abundance In Dairy Cattle, Jorge Luis Bonilla Urbina

Electronic Theses and Dissertations

The newly proposed physically adjusted NDF system (paNDF) system aims to maintain a favorable rumen environment (e.g., pH) by taking into account both the physical and chemical composition of diet. Thus, the objective of this study was to determine the effects of water-soluble carbohydrates (WSC) and non-forage NDF inclusion in a paNDF system on production performance, rumen pH and fermentation profile, rumen bacterial abundance, feeding behavior and nutrient digestibility in late-lactating Holstein cows. Nine fistulated multiparous Holstein cows (2nd and 3rd parity) were used in a triplicated 3×3 Latin Square experiment. Each period lasted for 21 d with 14 d …

Evaluation Of Yeast Postbiotic In Sow Diets On Sow And Offspring Performance And Microbial Succession, Joel Kieser

Electronic Theses and Dissertations

Litter size and the resulting nutritional demand on the sow continue to increase while sow mortality and culling rate are also increasing. Non-nutritive feed additives may enhance sow health and thereby improve offspring growth and productivity after weaning. Development of the gut microbiome in piglets via microbial succession is critical for maximizing their productivity and providing stability for overcoming weaning stress. The objective of this study was to evaluate the impact of yeast-based postbiotic supplementation in gestation and lactation diets on offspring performance through the nursery period and on whether a yeast postbiotic could impact the sow fecal microbiome as …

Soil Health Influenced By Livestock And Cover Crops Integration In Row Cropping Systems In South Dakota, Namrata Ghimire

Electronic Theses and Dissertations

No abstract provided.

Dynamic Modeling Of Commercial-Off-The-Shelf Smart Inverters Using Power-Hardware-In-The-Loop, Bidur Poudel

Electronic Theses and Dissertations

Inverter-based generation is replacing synchronous-based generation in the power grid. In the past, due to the dominance of synchronous-based generation, inverter-based generation dynamics were typically under-modeled as they made little contribution to voltage and frequency control. Looking at the present context, several disturbances, like the Blue Cut Fire (CA), on August 16, 2016, the South Australian Blackout on September 28, 2016, and the Canyon Two Fire Disturbance (CA) on October 9, 2017, etc., are caused by the influence of converter-based resources. So, for converter-dominated power system stability analysis and control, the dynamics of an inverter-based system cannot be under-modeled. In …

Effect Of Genotypes On Rancidity Development During Storage Of Naked Oats, Aastha Gautam

Electronic Theses and Dissertations

Oats, rich in lipids, lipase, and unsaturated fatty acids, can develop bitterness from triglyceride hydrolysis and unpleasant aromas through unsaturated fatty acid oxidation. To counteract these effects, the processing of hulled oats includes kilning, a step aimed at inactivating the enzymes responsible for lipid degradation. Kilning plays a crucial role in preserving the quality of oats by preventing undesirable flavors development linked to lipid breakdown. Despite the benefits of free threshing and absence of a dehulling requirement in naked oats, assessing lack of enzyme inactivation during processing is crucial for potential storage rancidity issues. Our aim was to determine the …

Comprehensive Analysis And Forensic Investigation Of Cyanide, Thiocyanate, And 2-Amino-2-Thiazoline-4-Carboxylic Acid In-Ante- And Postmortem Blood Utilizing Advanced Analytical Techniques, Abdullah Hamad Alluhayb

Electronic Theses and Dissertations

Cyanide (CN), present as cyanide anion (CN-) or hydrogen cyanide (HCN), is a deadly poison. The main mechanism of CN toxicity is blocking terminal electron transfer, leading to cellular hypoxia, cytotoxic anoxia, and potential death. Determining blood CN concen-trations along with its major metabolite, thiocyanate (SCN-), is crucial. A sensitive method for concurrent detection of CN and SCN- from human ante- and post-mortem blood via liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) analysis was devel-oped. The method involved active microdiffusion with chemical modification using naph-thalene-2,3-dicarboxaldehyde (NDA) and taurine, while monobromobimane (MBB) mod-ification was used for SCN-. The method showed good sensitivity for …

Phosphate2 And Pin-Likes7 Affect Symbiotic Nodule Phenotypes In Soybean, Bhawandeep Kaur

Electronic Theses and Dissertations

Legumes and soil rhizobia share a symbiotic relationship, wherein rhizobia fix atmospheric dinitrogen in exchange for photosynthates from the host plant. This exchange of mutual benefits occurs in a specialized root structure called ‘nodule’. Soybean (Glycine max) nodules arise from root outer cortical cells. De novo cell differentiation of cortical cells during nodule development leads to the formation of two distinct nodule zones in the mature nodule: the central infection zone where nitrogen fixation occurs and the peripheral parenchyma zone that houses vascular bundles. Plant signaling mechanisms that dictate the development of these nodule zones are not known. To address …

Factors Influencing Mortality Of Bighorn Sheep (Ovis Canadensis), Emily Moberg

Electronic Theses and Dissertations

Reintroduced bighorn sheep (Ovis canadensis) in Nebraska faced a devastating pneumonia epizootic resulting in variable ewe reproductive success and poor lamb recruitment in many of the herds. From 2015-2017, no lamb recruitment was observed in the northern Pine Ridge subpopulation and as many as 60% of adults died. This was in stark contrast to the healthier Wildcat Hills herds to the south, where lamb recruitment was estimated to be between 50-70% during the same years. From 2018-2020, we radio-collared and recaptured 76 adult female bighorn sheep from 2 of 3 Pine Ridge herds and 1 of 2 Wildcat Hills herds. …

Relations Between Parent Coping With The Stress Of Parenting And Symptoms Of Anxiety And Depression, Maxwell Jared Luber

Electronic Theses and Dissertations

It is important to refine understanding of the impact of adolescent behaviors on parents. In particular there is a need to improve understanding of the potential increase in parental distress caused by challenging youth behaviors. Parenting stress may play a critical role in these processes. Various coping strategies have been associated with different psychosocial outcomes, including anxiety and depression. In contrast, less effective coping strategies are linked to a higher likelihood of meeting criteria for mood or anxiety disorders. Gender differences in stress coping between women and men may contribute to women reporting higher levels of psychological distress, depression, and …

Investigating Novel Applications Of Hot Melt Extrusion Technology For Improving Solubility Of Poorly Soluble Drug Substances, Preethi Mandati

Electronic Theses and Dissertations

In today’s world, with an increasing patient population, the demand for pharmaceutical medications is increasing enormously. Poor solubility of the drug substances is the major issue being faced by scientists across various avenues of pharmaceutical sectors for improving oral bioavailability and delivering cost-effective medication to the patient population. To date, various approaches have been investigated for solubility enhancement. Despite improving the solubility, the limitations of batch manufacturing are another major roadblock affecting late-stage manufacturing. In addition, the traditional batch manufacturing techniques involve multiple manufacturing steps and lack the capability to manufacture complex and patient-centric medications. The current research aims to …

Experimental And Modeling Approaches To Groundwater Flow And Self-Potential For Estimating Aquifer Parameters And Investigating Surface-Groundwater Interaction, Md Lal Mamud

Electronic Theses and Dissertations

This dissertation presents an exploration of the Self-Potential (SP) and Electrical Resistivity Tomography (ERT) methods applied within the context of the Managed Aquifer Recharge (MAR) project near the Tallahatchie River at Shellmound, MS. The research introduces tools and methodologies, including 80-electrode SP data acquisition systems (80E-SPDAS) and the Hydro-Electrical Aquifer Properties Estimator (HEAPE), to measure SP data in the laboratory and the field. The first segment of the dissertation introduces the Hydro- Electrical Aquifer Properties Estimator (HEAPE), an apparatus designed for high-resolution Self-Potential (SP) data collection. The HEAPE apparatus is utilized in laboratory experiments to measure SP under varying conditions …

Impact Of Cardiovascular And Mental Health Comorbidities On All-Cause Healthcare Utilization Among Older Patients With Type 2 Diabetes, Prachi Prajapati

Electronic Theses and Dissertations

Background: More than 85% type 2 diabetes mellitus(T2DM) patients have at least one other comorbid condition. Recent data has shown an increase in cardiovascular (CVD) and mental health conditions (MHD) among diabetes patients. Because of the pathological difference in CVD and MHD, their management is unique. We may see differential utilization of healthcare services among T2DM patients with these comorbidities. The study’s aim was to estimate the prevalence of CVD and MHD among older T2DM patients and to assess the comparative healthcare utilization among T2DM patients with these comorbidities by service type.

Methodology: A retrospective cohort analysis was conducted using …

Night Bites: The Relationship Between Sleep Quality, Binge Eating, And Night Eating, Mccall Schruff

Electronic Theses and Dissertations

Obesity is a chronic disease and classified as a global epidemic. Its incidence has rapidly increased worldwide, particularly within the United States where associated adverse health consequences have led to substantial increases in premature mortality, health-care utilization, and spending. Given the biopsychosocial nature of obesity, it can be considered a preventable health-risk that is a major public health concern. Associated risk factors, such as insufficient quality and quantity of sleep, binge eating, and night eating, could worsen health outcomes, as research suggests these symptoms rarely occur in isolation and are more frequent in individuals with higher body mass index. In …

Novel Formulation Strategies With Hot-Melt Extrusion Technology To Address Physicochemical And Physiological Constraints For Improved Oral Drug Delivery, Sagar Narala

Electronic Theses and Dissertations

Most current active pharmaceutical ingredients (APIs) exhibit poor water solubility, necessitating higher doses or repeated administration. Numerous methods were explored to augment solubility, including but not limited to amorphous solid dispersions, cocrystals, salts, and nanoformulations. The hot-melt extrusion (HME) technique has gained immense popularity due to its solvent-free and continuous manufacturing capabilities, contributing to its increasing use to enhance solubility and bioavailability. In the first chapter, hydrochlorothiazide (BCS-IV class) cocrystals were produced using coformers such as nicotinamide (NIC), resorcinol (RSL), and catechol (CAT) through HME technology. The cocrystals were compared against liquid-assisted grinding (LAG) cocrystals and then analyzed by DSC, …

Increasing Primary Care Physicians Through Rural Medicine Curriculum, Margaret Pickering Wilson

Electronic Theses and Dissertations

The citizens of rural areas encounter many challenges with accessing primary healthcare. Mississippi meets 52.1% of the needs of the state for primary care physicians, causing citizens to travel farther distances to access health care. Many rural hospitals within the state are struggling financially and are at high risk of closing, causing further barriers for rural citizens to access healthcare. Increasing primary care physicians help provide adequate healthcare access and provides rural citizens access to preventative care and early treatment for health problems.

This study, conducted at the University of Mississippi Medical Center, seeks to determine if rural medicine courses …

A Discrete Conley-Zehnder Index For Symplectic Polytopes, Yutian Yu

Electronic Theses and Dissertations

A Hamiltonian system is a dynamical system governed by Hamilton’s equations. Hamiltonian systems provide a framework for studying classical mechanics. One fundamental principle in Hamiltonian mechanics is the conservation of energy along the flow of the Hamiltonian vector field. The smooth hypersurface of a Hamiltonian function on a symplectic manifold has a contact structure, and the associated Reeb vector field is, up to a scale, the Hamiltonian vector field. We are interested in the non-smooth case and a symplectic polytope makes a good model to study.

In this dissertation, we study the Reeb dynamics on the boundary of a symplectic …

Cosplay Fandom Leisure Engagement: Exploring Cosplay Participation And Involvement On Depression And Wellbeing Toward A Recreation Therapy., Julie A. Morris Chambers

Electronic Theses and Dissertations

Engagement in leisure is a complex construct that impacts wellbeing beyond mere participation. Moreover, researchers have explored engagement in various ways including what people do and experience in their personal pursuit of leisure activities (Kleiber et al., 2011). Studies show that leisure engagement positively effects participants' wellbeing and reduces their ill-being. The purpose of this study is to explore the level of cosplay leisure engagement and wellness and mental health of DragonCon (DC) attendees to illuminate if their cosplay engagement has therapeutic effects on wellness, perceived wellness, and depression. In this study, Newman (et al., 2013) and Kuykendall (et al., …

Acute Countermovement Jump Performance In Collegiate Distance Runners, Kristel Tessa Van Den Berg

Electronic Theses and Dissertations

Introduction: Running is the most popular form of physical activity worldwide and it has a positive effect on the overall health. However, (competitive) running is also associated with stress injuries. Stress injuries can be caused by overtraining. Countermovement jumps (CMJ) have previously been used to monitor training load and neuromuscular fatigue in athletes of multiple sports. However, this has not been explored in distance runners yet. Therefore, the purpose of this study is to assess if countermovement jump (CMJ) performance in collegiate distance athletes has a relationship to neuromuscular fatigue.

Methods: In total 12 female and 15 male distance runners …

Has Journalism Education Kept Up With Digital Transformation?, Md Sazzad Hossain

Electronic Theses and Dissertations

In the digital world, journalism is a highly technology-dependent profession (Goni & Tabassum 2020). But there are gaps between what journalism schools teach and what employers want (Wenger and Owens, 2013). As a result, students, educators, and professionals demand the development of specific digital skills (Lee 2022). This study examines how journalism educators adapt their programs to respond to changing media environments and to the demands of professional journalism in the digital age. The researcher used a quantitative survey method to target the 119 journalism and mass communication programs accredited by the Accrediting Council on Education in Journalism and Mass …

Who, What, And How Much: Understanding The Profiles, Preferences, And Valuations Of Individuals Likely To Participate In Food As Medicine Programs, Austin Dean Arnold

Electronic Theses and Dissertations

Background: Initial research on food as medicine programs has shown encouraging evidence, but more evidence is needed to identify the most effective models, services, delivery methods, and funding mechanisms. Previously studied programs were designed by the researchers, providers, and public health advocates without input from patients on their preferences. Patient engagement is essential to develop successful programs.

Study Aims: 1) To explore the presence latent classes among individuals with diet-related chronic diseases likely to participate in food as medicine programs; 2) To explore preferences for attributes of food as medicine programs among individuals with diet-related chronic diseases likely to participate; …

The University Of Mississippi’S First-Year Experience Course: A Quantitative Analysis, Rachael Durham

Electronic Theses and Dissertations

First-year seminar courses have become increasingly popular for colleges and universities as they are expected to help aid in the transition to college and help students persist to graduation (Culver & Bowman, 2020).

Utilizing pre-existing data from the Office of Institutional Research Effectiveness and Planning (IREP), the scholar-practitioner evaluated EDHE 105, the freshman academic orientation course, at the University of Mississippi. The anonymized data file included demographic information of residency, gender, and ethnicity, high school grade point average, ACT composite scores, enrollment in EDHE 105, athlete and honors designations, first-semester grade point average, fourth-semester grade point average, fourth-semester hours attempted, …

Voices From Below: The Politics Of Leprosy Control In Southeastern Nigeria, 1926-1960, Odinakachukwu Kingsley Eze

Electronic Theses and Dissertations

Leprosy was an endemic disease in colonial Southeastern Nigeria but became an epidemic between the 1920s and 1940s. Unlike malaria and sleeping sickness, its endemicity did not impede European penetration at the dawn of the twentieth century. However, its spread across Nigeria intensified during colonial rule, with acute prevalence in regions hitherto prone to the disease. Therefore, from the 1920s to 1960, Southeastern Nigeria became the epicenter of British policies tailored towards preventing, curing, and eradicating leprosy disease in Nigeria. Existing research has established the involvement of different actors in this course–including Christian missionaries, colonial officials, specialized agencies, and international …

Molecular Dynamics Simulations For The Mechanical Behavior Of Alpha Quartz With Void Defects Under Tension, Yu Jia

Electronic Theses and Dissertations

The structural and mechanical properties of void-free and single-void α-quartz were investigated using MD simulations with three different interatomic potentials (BKS, Vashishta and Tersoff). Two distinct ensembles, NVT and NPT, were separately applied to investigate the tensile response of α-quartz under uniaxial strain and uniaxial stress states. A comprehensive comparison among different potentials, as well as comparison with currently available experiments, has been made. The BKS and Vashishta potentials accurately predicted the structural properties of void-free α-quartz, while the Tersoff potential was deviated significantly from the experimental data. Under tension, the BKS did a better description for the mechanical performance …