Digital Commons Network^™

The Role Of Sibling Configuration In Identity And Career Development, Alyssa Sullinger

Electronic Theses and Dissertations

This synthetic literature review examines the characteristics of sibling configurations— which refer to the ordinal position of siblings, age spacing, and sex composition—in a traditional family setting. A general review of the literature on sibling configurations and relationships is presented, and their potential roles in the development of personality traits, self-concept and identity, and career choices are explored. This synthesis describes how sibling birth rank is affiliated with generalized personality traits and likelihood of siblings with these traits identifying with corresponding career interest-types associated with Holland’s vocational theory. Suggestions for future research include empirical studies investigating these connections, such the …

The Salvation Of The Cosmos: Benedict Xvi's Eschatology And Its Relevance For The Current Ecological Crisis, Jeremiah Vallery

Electronic Theses and Dissertations

Pope Emeritus Benedict XVI has elements of a cosmic eschatology embedded in his theological oeuvre that have not heretofore been extensively systematized. This dissertation fills this gap by contextualizing Benedict’s cosmic eschatology in the twentieth and twenty-first centuries, examining his Logos theology and his view on the fate of the cosmos, exploring his cosmic liturgy, and evaluating his concept of human ecology and pneumatology. Benedict insufficiently links his cosmic eschatology to his papal teachings on the environment; however, his cosmic eschatology can be developed in fruitful ways. After providing a thorough articulation of Benedict’s cosmic eschatology, I offer my own …

An Exploration Of The Relationships Among Cattell-Horn-Carroll (Chc) Theory-Aligned Cognitive Abilities And Math Fluency, Katherine D. Piselli

Electronic Theses and Dissertations

Math fluency, which refers to the ability to solve single digit arithmetic problems quickly and accurately, is a foundational mathematical skill. Recent research has examined the role of phonological processing, executive control, and number sense in explaining differences in math fluency performance in school-aged children. Identifying the links between these cognitive abilities and math fluency skills has important implications for screening, assessment, and intervention efforts in schools. As extant mathematics research in the context of Cattell-Horn-Carroll (CHC) theory has evaluated either broad mathematics performance or math calculation skills, little is known about the specific relationships between math fact fluency and …

Indirect Bullying And Conflict Management Skills In Childhood And Adolescence, Charles Albright

Electronic Theses and Dissertations

In this study, the Young Adult Social Behavior Scale (YASB) and Conflict Resolution Scale (CRS) measures were administered to students from three private middle and high schools in the mid-Atlantic US as part of a larger study regarding the effects of a group counseling curriculum in reducing forms of indirect bullying. Research questions were developed to evaluate differences according to student age and gender in relational aggression, social aggression, and interpersonal maturity, as well as relationships between relational aggression, social aggression, interpersonal maturity, and conflict resolution skills. These questions were evaluated using MANOVA, Chi-square, and multivariate regression analyses, respectively. Results …

Burden Of Illness And Pharmacoeconomic Evaluation Of Lumacaftor/Ivacaftor In Cystic Fibrosis, Pratyusha Vadagam

Electronic Theses and Dissertations

Objectives: (1) To estimate the burden of illness in cystic fibrosis (CF) using 2010-2014 Medical Expenditure Panel Survey (MEPS) data, and (2) to conduct a pharmacoeconomic evaluation of lumacaftor/ivacaftor in the treatment of CF.

Methods: The study was conducted in two parts. Part 1 involved a retrospective analysis using individuals in MEPS database with an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis code of 277.00 for a principal diagnosis of CF. Dependent variables were cumulative and out-of-pocket (OOP) expenditures and independent variables included patient demographics and clinical characteristics. Unweighted and weighted estimates of expenditure in CF group, …

A Phenomenological Investigation Of Sport And Fandom Through Hans-Georg Gadamer And Maurice Merleau-Ponty, Alexander Regina

Electronic Theses and Dissertations

This project aims to uncover the phenomenological and communicative roots of sport fandom from the fan perspective, taking into account the many ways in which fans come to contact sport and integrate corresponding experiences into their own lives and sense of being in the world. Hans-Georg Gadamer and Maurice Merleau-Ponty are used to understand the conventions of play that manifest in sport, leading not only to the co-creation of the game experience due to the intertwining of spectators and players but also to the interplay of temporal realms that leads to what Gadamer calls the fusion of horizons. Through …

Molecular Analysis Of The Mating System Of A Population Of Fantail Darter (Etheostoma Flabellare) In Bates Fork, Greene Co., Pa, Ashley Seitz

Electronic Theses and Dissertations

In May 2013, we examined the mating system of the Fantail Darter, Etheostoma flabellare, from a population inhabiting Bates Fork, a small tributary of the Monongahela River in Greene County, PA. Guarding adult male Fantail Darters excavate an area under a flat rock in moderately flowing rifles. Females select a male or his territory and deposit clusters of eggs on the underside of the nest rock. The guarding male provides all parental care. The locations of 23 nests were mapped over a 139m² stream segment before collecting embryos and attending males for a genetic parentage analysis. DNA was …

“Forming Ranks”: The Impact Of Negative-Destructive Leadership In The Aftermath Of Military Sexual Assault And Reporting, Jessica Payton

Electronic Theses and Dissertations

Military leaders play central roles in responding to sexual assault in the military social ecology, yet their impacts on victims’ post-assault and reporting experiences remain understudied. Using standpoint epistemology and a military-specific social ecological approach, this two-stage project investigated how military leaders impacted survivors’ post-assault and reporting experiences, as well as their experiences with military peers, community resources, and justice and separation processes. Data were gathered through an initial focus group with eight subject matter experts in advocacy, legal work, and policy reform, followed by subsequent in-depth individual interviews with eight female survivors of military sexual assault, seven of whom …

A Day Through My Eyes: Improving Visual Perceptual Training For School Staff Members Working With Students With Autism Spectrum Disorder, Abigail Moonis

Electronic Theses and Dissertations

A Day Through My Eyes focuses on the topic of visual perception in school-age children with autism spectrum disorder (ASD). This program addresses a need to improve the training, knowledge, and skills within the area of visual perception amongst school staff members working at Bridgeway Academy. This program contains three interrelated components to address these needs: an all staff training, development of an occupational therapy based assessment tool for visual perception, and the training of occupational therapy staff members on the use of the assessment too as well as incorporating visual perception resources into treatment. Results of this program indicate …

Schelling's Ages Of The World: The Beginning Of The Beginning, Andrew Jussaume

Electronic Theses and Dissertations

This dissertation traces the development of Schelling's philosophy of time as it appears in the Ages of the World, a work which Schelling himself never completed but which he clearly intended as his magnum opus. My project focuses on Schelling's claim that time is the absolute, a claim which grew out of his Naturphilosophie and which later served as the basis for his fruitful interactions with Kierkegaard in Berlin. In the dissertation, I defend the thesis that Schelling's concept of "beginnings" paves the way for an "organic" understanding of time which articulates the latter as a living, breathing entity. In …

Improving The Practice And Culture Of Early Learning In Ohio, Diana Morello-Deserio

Electronic Theses and Dissertations

How can preschool programs situated in public schools “get better at getting better?” This dissertation suggests a framework based on the principles of Improvement Science as one-way school districts can include preschool in their continuous improvement efforts. Document Analysis, is the method used to examine a continuous improvement protocol used in Ohio school districts known as The Ohio Improvement Process (The OIP Guide was the document analyzed). Additionally, Portraiture as “lived” experiences including both early learning educators and traditional school age leaders were reflected upon. The following research questions guided the study: What are the key operational components of the …

The Normative Approach Of The Catholic Tradition In The Ethical And Religious Directives For Resolving Ethical Dilemmas Regarding Medical Technology, David G. Garvis

Electronic Theses and Dissertations

The dissertation engages the Catholic Tradition enunciated in the Ethical and Religious Directives for Catholic Health Care Services to provide a normative approach for resolving ethical dilemmas regarding pivotal breakthroughs in medical technology.

This normative ethical approach has two components: a normative framework for Catholic health care ethics that adopts practical ethical principles as enunciated in the Ethical and Religious Directives (Chapter 2) and secular decision-making models in organizational and clinical ethics that are consistent with the Catholic Tradition (Chapter 3).

At the end of the theoretical analysis in these chapters, the conclusion to Chapter 3 explains how this normative …

The Decline And Recovery Of Thermal Oxidative Stability Of Ultra-Low Sulfur Diesel Blends, Abigail Schoor Cohen

Electronic Theses and Dissertations

Dissertation supervised by Professor Bruce D. Beaver

The oxidative stability of ultra-low sulfur diesel (ULSD) has generally been expected to continuously decline over time. However, recent studies have suggested that it may fluctuate.^1-2 In this study, the oxidative stability of stored commercially purchased ULSD was monitored with a methanol extraction method.³ In this methodology, proposed by Hardy and Wechter, fuel blends are extracted with methanol before and after thermal stressing.⁴ The methanol-soluble layer contains the oxygenated and oxidizable components of the fuel (SMORS) and the change in this mass upon stressing thus represents the oxidative stability of …

Discovery Of Pyrimidine-Based Heterocycles As Single Agents With Combination Chemotherapy Potential And As Inhibitors Of Purine Nucleotide Biosynthesis For The Treatment Of Cancer, Rishabh Mohan

Electronic Theses and Dissertations

This dissertation describes the design, synthesis and biological evaluation of monocyclic and bicyclic pyrimidine-base heterocycles as single agents with combination chemotherapy potential having both antiangiogenic effects and cytotoxic effects. This dissertation also describes selective tumor targeting with 5-substituted pyrrolo[2,3-d]pyrimidines analogs with heteroatom bridge substitution as GARFTase inhibitors.

The work in this dissertation is centered on identifying structural features that are necessary for inhibition of tubulin polymerization as well as for inhibition of one or more of the receptor tyrosine kinases (RTKs)- vascular endothelial growth factor receptor-2 (VEGFR2), platelet derived growth factor receptor-β (PDGFRβ) and epidermal growth factor receptor …

The Church In Dialogue With Other Religions In The Postmodern World: Reflecting Beyond Nostra Aetate., Daniel Aboagye Adjei

Electronic Theses and Dissertations

The church has accomplished tremendous strides in interfaith dialogue within the past fifty-two years after the promulgation of Nostra Aetate, the declaration which opened a positive and revolutionary avenue for the church in her dialogical encounter with the non-Christian religions. This project praises Nostra Aetate for the bold step in entering the unfamiliar terrain in the church’s dialogue with non-Christian religions, by affirming in these religions “ray of truth,” “seed of the gospel,” element of “truth and holy” and reproving as foreign to the Christian faith any discrimination and harassment against people based on culture, race, condition in life and …

Target Based Design And Synthesis Of Heterocycles In The Potential Treatment Of Cancer And Opportunistic Infection, Shruti Choudhary

Electronic Theses and Dissertations

Dose limiting toxicity and development of multidrug resistance by the tumors are the major limitations of current cancer chemotherapy. Microtubule targeting agents (MTAs) are a structurally diverse set of compounds that disrupt microtubule dynamics and exert their anticancer effect. Among the various classes of such agents, the colchicine site binding agents are particularly important as they circumvent the Pgp and β-III tubulin mediated clinical resistance. These resistance mechanisms, when manifested, are a major reason for the failure of clinically used agents such as taxanes and vinca alkaloids. A series of monocyclic pyrimidine analogs were designed and synthesized as colchicine site …

Target Based Design And Synthesis Of Fused Pyrimidines In The Potential Treatment Of Cancer And Opportunistic Infection, Khushbu Shah

Electronic Theses and Dissertations

This dissertation describes an introduction, background and research progress in the areas of agents designed as (a) selective Pneumocystis jirovecii dihydrofolate reductase (pjDHFR) inhibitors for pneumocystis pneumonia (PCP) infection; (b) inhibitors of microtubule polymerization and multiple receptor tyrosine kinase (RTK) for potential treatment of cancer; and (c) substrates for tumor-targeted therapy for cancer.

PCP is a host species-specific infection. Most of the drugs, synthesized and evaluated so far, have been tested against Pneumocystis carinii dihydrofolate reductase (the causative organism in rats), which would not necessarily be effective against pjDHFR (the causative organism in humans). Trimethoprim-sulfamethoxazole (TMP-SMX) combination, which has been …

Parents Of Children Who Had Hypoxic-Ischemic Encephalopathy: A Mixed-Methods, Exploratory Study, Natalene Kramer

Electronic Theses and Dissertations

Background: There is scant literature addressing the parents of children who had hypoxic-ischemic encephalopathy (HIE). therefore only inferences may be made as to issues of that experience affecting parents.

Purpose: The purposes of this study was to uncover the lived experiences of parents of children who had HIE, evaluate issues of stress, depression, coping, and impact of neurologic disability in order to better care for them and thus their families

Methods: A parallel, convergent mixed-methods design was used to explore experiences and perceptions of these parents regarding their experiences and life changes. The quantitative strand addressed four research questions which …

Nickel Reduces Calcium Dependent Dimerization In Neural Cadherin, Matthew Paul Dukes

Electronic Theses and Dissertations

Cadherins are the primary transmembrane component in adherens junctions, structures that link the actin cytoskeleton in adjacent cells within solid tissues including neurological synapses, epithelium and endothelium. Cell-cell adhesion by cadherins requires the binding of calcium ions to specific sites in the extracellular region. Given the complexity of the cell adhesion microenvironment, we are investigating whether other divalent cations might affect calciumdependent dimerization of neural-(N-) cadherin. The first chapter focuses on studies to characterize the impact of binding physiological magnesium (II) or neurotoxic nickel (II) on calcium-dependent N-cadherin function. Physiological levels of magnesium have only a small effect on the …

Rewiring The Anger: Learning New Responses In The Therapeutic Community, Emma Marie Burleson

Electronic Theses and Dissertations

Extensive research has been conducted in correctional settings on the effects that therapeutic programs that utilize cognitive-behavioral therapies have on recidivism rates and cognitive-behavioral changes among inmates. Research on anger management programs in correctional settings has shown that there are measurable effects on the anger levels of participants based on quantitative pre-testing and post-testing. The present study sought to build on this research in a unique way by conducting qualitative research to examine the personal perceptions of inmates that have graduated from a therapeutic program in a maximum security prison. The study focused on participants’ perceived changes in how they …

Maximizing Cache Value For Distributing Content Via Small Cells In 5g, Ibrahim Khalaf Freewan

Electronic Theses and Dissertations

The objective of this thesis is to develop an algorithm for distributing content at small cells in 5G, wherein small cells (SCs) are set up instead of macro cells to serve mobile users. Users may simultaneously access between one and some maximum number of SCs, the actual number of SCs being drawn from a distribution. The source library is located away from these sites, and it stores files as a collection of RaptorQ-encoded symbols. By using RaptorQ symbols a very large number of distinct encoding symbols can be generated and a collection of received encoded symbols slightly larger than the …

Diet Quality And Food Insecurity Among University Students: The Role Of Food Preparation Ability, Katharine Halfacre

Electronic Theses and Dissertations

No abstract provided.

Creating A Stormwater Runoff Model For The City Of Oxford, Mississippi: When It Rains, Where Does That Water Go?, Alexandra Gay Weatherwax

Electronic Theses and Dissertations

The city of Oxford, Mississippi (home of the University of Mississippi) has experienced, in recent years, a rapid growth of urbanization. This rapid increase creates more impervious cover, such as bridges, roads, parking lots, etc., which can cause a stress on the capacity of stream load and causes flooding. To correct this, storm water management is needed in the city. This stormwater runoff model uses data collected from rain gauges, soil data from ssurgo and published soil infiltration rates from a Lafayette County soil survey, impervious cover created from Lidar and Aerial Photography, published evapotranspiration rates, and storm drain locations …

Natural Disasters, Incidents Of Mass Violence, And Preparedness On A College Campus: A Study Of University Faculty And Staff, Marcela Caroline Weber

Electronic Theses and Dissertations

The objective of this study was to examine previous disaster impact, threat perception, self-efficacy, and sex as predictors of university employees’ preparedness for natural disasters and incidents of mass violence. A cross-sectional survey was conducted with faculty and staff members (N = 410) at a medium-sized university located in the southern United States. Employees’ sex, disaster experience, impact of that experience, perceived threat, and self-efficacy were examined as predictors of actual preparedness, across a range of natural disasters and incidents of mass violence. Drawing from the Extended Parallel Process Model (EPPM; Figure 1), a moderated mediation model (Figure 2) was …

Native Music And Regular Gigs: A History Of The Maple Leaf Bar, Pieter Frank Kossen

Electronic Theses and Dissertations

The purpose of this work is to construct a history of the Maple Leaf Bar in New Orleans, Louisiana in order to determine its place and establish its importance in the musical history of New Orleans. Opened in early 1974, the Maple Leaf Bar is the oldest continually-functioning music club in the city of New Orleans outside of the French Quarter, and is accorded a share of the credit for the current popularity in New Orleans of the roots music of New Orleans and Louisiana. This will be accomplished by identifying and examining comtraits the Maple Leaf Bar shares with …

Beyond Isolation: The Mississippi Delta In A Global World, Stella D. Lindsey

Electronic Theses and Dissertations

This study examines the paradoxes and complexities of the Mississippi Delta through an international lens. The fundamental premise guiding the research is that goods, people, ideas, technology, and capital cross national borders; therefore, local transformations can only be fully understood within a global context. The study concentrates on the evolution of the reciprocal, complex relationship between the region and the international community, along with the local and global consequences of a series of transnational exchanges. With a primary focus on agribusinesses, the research challenges traditional visions of the Delta as an isolated and provincial region immune to modernization. Instead the …

Patient Friendly Formulations Utilizing Hot Melt Extrusion Technology, Manjeet Bhagwan Pimparade

Electronic Theses and Dissertations

This research work exhibited the new outlook of hot melt extrusion technology for orally disintegrating tablet, fast disintegration films and fixed dose combinations. Previous research demonstrated these applications by conventional formulation techniques which has inherent shortcoming of use of large amount of solvent and batch size manufacturing. This present work addressed some of the unique challenges which could provide patients ease of administration and reduce dosing frequencies, and moreover, mitigate the manufacturing challenges. For orally disintegrating tablet study, ethylcellulose, along with a suitable plasticizer, was used as a polymeric carrier. Pore forming agents were incorporated into the extruded matrix to …

High School Contextual Variables And Act Scores, John-Mark Cain

Electronic Theses and Dissertations

This quantitative study analyzes findings from the 2015 Crepe Myrtle High School (CMHS) graduates and determines if statistically significant relationships exist between student demographic and school participation variables with ACT composite scores. Utilizing both a Pearson product moment statistical correlation and t-test for continuous variables and a One-Way Analysis of Variance (ANOVA) for categorical variables, the researcher identifies and presents significant relationships or differences in means, between the academic achievement of 2015 Crepe Myrtle High School graduates and ACT composite scores. The variables analyzed consists of: (a) the number of completed core classes; (b) high school grade points averages (HSGPAs); …

Three Essays On Private Market Interactions, Jonathan Daigle

Electronic Theses and Dissertations

The first study addresses why insurers, whom traditionally invest in relatively safe assets, choose to invest in private equity (PE). Using insurer financial disclosures, we test theories relating how risk shifting, managerial discretion, underinvestment, asset liability matching, regulation, home bias, and reaching for yield affect PE investment. Results indicate risk¬ shifting and managerial discretion by stock insurers does not factor into the PE investment decision. In addition, results confirm home bias positively influences PE investment while underinvestment, asset liability matching, and regulation deter PE investment. Finally, insurers have not increased their PE allocation due to low-yield interest rate environments. The …

Succeeding King: Ralph David Abernathy, Sclc, And The Long Civil Rights Movement, Scott Blusiewicz

Electronic Theses and Dissertations

As president of the Southern Christian Leadership Conference, Martin Luther King Jr. emerged as America’s most prominent civil rights activist during the late 1950s and the 1960s. Due to his eloquent speeches and ability to organize large-scale nonviolent protests, King inspired numerous individuals to participate in a grassroots movement for equal rights. After earning two landmark victories with the passage of the Civil Rights Act of 1964 and the Voting Rights Act of 1965, King and his SCLC colleagues shifted the focus of their work to improving economic opportunities for America’s poor citizens. To combat poverty, King planned an ambitious …