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Regulation Of Haplid Phenotypes In Ustilago Maydis By Ammonium Transporters And Components Of The B Mating Locus., Rena Margaret Wallen

Electronic Theses and Dissertations

Fungi that can switch from budding to a filamentous infectious state have evolved mating type loci. Ustilago maydis, the maize pathogen, must mate with compatible partners possessing different alleles at two mating type loci for successful host infection. The a locus encodes pheromones and receptors, while the b locus encodes subunits of a heterodimeric transcription factor that regulates expression of virulence genes. Mating is triggered by environmental signals, including nutrient deprivation. My goal was to determine the fate of nitrogen starved haploid cells without a compatible mating partner. On solid low ammonium media, wild-type U. maydis filaments. I examined …

Interaction Style Of Mothers Of Young Children With Williams Syndrome And Relations With Child Expressive Vocabulary., Danielle R. Henderson

Electronic Theses and Dissertations

Children of a given age vary widely in their expressive vocabulary abilities. One factor that is related to child expressive vocabulary ability is the style in which the mother interacts with her child. Studies that have considered this relation for either typically-developing (TD) children or children with developmental or intellectual disability (DD/ID) (e.g., autism spectrum disorder, fragile X syndrome) have shown that children whose mothers have a more sensitive/responsive interaction style have significantly larger expressive vocabularies than do children whose parents have a less sensitive/responsive style (e.g., Baker et al., 2010; Belsky et al., 2007; Brady et al., 2014; NICHD …

Estimation Of The Three Key Parameters And The Lead Time Distribution In Lung Cancer Screening., Ruiqi Liu

Electronic Theses and Dissertations

This dissertation contains three research projects on cancer screening probability modeling. Cancer screening is the primary technique for early detection. The goal of screening is to catch the disease early before clinical symptoms appear. In these projects, the three key parameters and lead time distribution were estimated to provide a statistical point of view on the effectiveness of cancer screening programs. In the first project, cancer screening probability model was used to analyze the computed tomography (CT) scan group in the National Lung Screening Trial (NLST) data. Three key parameters were estimated using Bayesian approach and Markov Chain Monte Carlo …

Likelihood-Based Methods For Analysis Of Copy Number Variation Using Next Generation Sequencing Data., Udika Iroshini Bandara

Electronic Theses and Dissertations

A Copy Number Variation (CNV) detection problem is considered using Circular Binary Segmentation (CBS) procedures, including newly developed procedures based on likelihood ratio tests with the parametric bootstrap for models based on discrete distributions for count data (Poisson and negative binomial) and a widely-used DNAcopy package. Results from the literature concerning maximum likelihood estimation for the negative binomial distribution are reviewed. The Newton-Raphson method is used to find the root of the derivative of the profile log likelihood function when applicable, and it is proven that this method converges to the true Maximum Likeihood Estimate (MLE), if the starting point …

Regularized Solutions For Terminal Problems Of Parabolic Equations., Sujeewa Indika Hapuarachchi

Electronic Theses and Dissertations

The heat equation with a terminal condition problem is not well-posed in the sense of Hadamard so regularization is needed. In general, partial differential equations (PDE) with terminal conditions are those in which the solution depends uniquely but not continuously on the given condition. In this dissertation, we explore how to find an approximation problem for a nonlinear heat equation which is well-posed. By using a small parameter, we construct an approximation problem and use a modified quasi-boundary value method to regularize a time dependent thermal conductivity heat equation and a quasi-boundary value method to regularize a space dependent thermal …

Transient Absorption Studies Of Cdse Nanocluster Passivated With Phenyldithiocarbamate Ligands., Yizhou Xie

Electronic Theses and Dissertations

Semiconductor nanocluster (SCNC) research is a rapidly growing field driven by the promising fact that properties of such materials can be tailored by modifying their size, shape, and structure. Combination of nanocluster and organic ligands provides even wider possibilities of design and development of effective and task-specific nanostructures. Understanding of and, eventually, control of energetics, interfacial interaction, and photoinduced processes in such highly heterogeneous structures is critical to invention of novel materials including those in photovoltaic devices. In the newly established Ultrafast Laser Facility (ULF), transient absorption pump-probe spectroscopy (TAPPS) has been employed to investigate the electron transfer (ET) and …

Sphingolipids In Models Of Kidney Disease And Injury., Tess V. Dupre

Electronic Theses and Dissertations

Acute kidney injury (AKI), resulting from cisplatin, remains an obstacle in the treatment of cancer. Cisplatin-induced AKI involves cell death pathways regulated by sphingolipids such as ceramide and glucosylceramide. Results indicate that cisplatin-treated mice had increased levels of ceramide and hexosylceramide. Pre-treatment of mice with inhibitors of ceramide synthesis prevented accumulation of ceramide and hexosylceramide in the renal cortex and attenuated cisplatin-induced AKI. To determine the role of ceramide metabolism to hexosylceramides in kidney injury, we treated mice with an inhibitor of glycosphingolipid synthesis. Inhibition of glycosphingolipid synthesis attenuated the accumulation of the hexosylceramide and exacerbated ceramide accumulation in the …

Get Thee To A Nunnery: Unruly Women And Christianity In Medieval Europe, Sarah E. Wolfe

Electronic Theses and Dissertations

This thesis will argue that the Beowulf Manuscript, which includes the poem Judith, Saxo Grammaticus’s Gesta Danorum, and the Old-Norse-Icelandic Laxdæla saga highlight and examine the tension between the female pagan characters and their Christian authors. These texts also demonstrate that Queenship grew fragile after the spread of Christianity, and women’s power waned in the shift between pre-Christian and Christian Europe.

Matter Under Mind, John F. Lause

Electronic Theses and Dissertations

The artist discusses the work for his Masters of Fine Arts exhibition, Mind under Matter, held at the Tipton Gallery in downtown Johnson City, Tennessee. Exhibition dates are from March 27th through April 5th 2017. ‘Matter under Mind’ explores the balance of control and non-control within the art-making process. This technique creates an automatic dialogue resulting in abstraction guided by the subconscious. The title ‘Matter under Mind’ is a slight play on the phrase ‘mind over matter’ emphasizing how matter/material is manipulated by the mind through the making of artwork, and within the mind’s eye or imagination.

The video installation …

Effects Of Lactobacillus Rhamnosus Mrs6an On Intestinal Gpat3 Pathway Involved In The Lipid Transport In Enterocytes, Ayodeji Oludare Ipinmoroti

Electronic Theses and Dissertations

Accumulation of triglyceride (TG) in enterocytes of the small intestine follows two specific absorption pathways: the monoacylglycerol acyltransferase pathway (MGAT) and glycerol acyltransferase pathway (GPAT), the latter (GPAT) is usually found in the small intestine. In this study, we investigated the effects of Lactobacillus rhamnosus MRS6AN, an isolate from “amabere amaruranu” a Kenyan traditional cultured milk, on triglyceride accumulation and expression of GPAT3, I-FABP, MTP and NPC1L1 in Caco-2 cell enterocyte model. Intracellular triglyceride level (TG) of Caco2 cells was significantly reduced by live L. rhamnosus (LB) compared with other bacterial products. MTP expression in Caco2 cells was minimally reduced …

A Study Of Salmonid Growth In Two Southern Appalachian Headwater Streams, Joshua Argo

Electronic Theses and Dissertations

This study sampled salmonid populations in two headwater streams in East Tennessee, Briar Creek and Left Prong Hampton Creek. Length and weight data were used to calculate the growth of these populations to determine if significant variation exists between isolated brook trout populations. Slope comparisons concluded that there was a difference in growth between brook trout populations of these streams (p

The Effects Of Employment On Recidivism Among Delinquent Juveniles, Leigh Kassem

Electronic Theses and Dissertations

Current research indicates an association between intense adolescent work (twenty hours or more per week) and delinquent behavior. It has been widely speculated that this relationship is spurious, occurring only as a result of other factors which are common to both offending and intense employment. The current study attempts to fill a gap in the literature by utilizing the Pathways to Desistance dataset to examine the evolution of the relationship between work and self-reported offending in a longitudinal sample of juvenile offenders. Work intensity and consistency, social capital, and expectations for success were analyzed as potential predictors of recidivism or …

Ecological Informatics: An Agent Based Model On Coexistence Dynamics, Shiva Thapa

Electronic Theses and Dissertations

The coexistence of species is probably one of the most interesting and complex phenomenon in nature. We constructed an agent based model to study the coexistence dynamics of prey - predator populations by varying productivity levels of producers in fragmented and connected habitats along with different levels of quality of predators. Our results indicated that productivity levels of producers in fragmented and connected habitats along with levels of predator quality are significantly responsible for overall predator - prey population size and survivorship. In the absence of predation, competition between identical prey populations is more probable in connected habitats than in …

Design Plan For The Sawmill Town History Wing At The Texas Forestry Museum, Kendall D. Gay

Electronic Theses and Dissertations

The Texas Forestry Museum in Lufkin, Texas is the only forestry museum in the state. It preserves artifacts and educates visitors about Texas’ forest industry history. The museum has a Sawmill Town History Wing that is outdated and in need of a refreshing exhibit design based on current best practices. Using a previous museum audit as a guide, the new exhibit will have better flow, panel aesthetics, content, and interactive elements. By creating a new exhibit, the museum is better able to educate and entertain the visitors about Texas’ forest industry history.

Restoring גלה Ii From Exile: Discovering The Homonyms Spelled ג-ל-ה By Examining Their Usage In The Hebrew Bible, Josiah D. Peeler

Electronic Theses and Dissertations

This thesis examines the evidence in the Hebrew Bible of the ancient Hebrew lexeme גלה. The aim is to determine how many roots are represented by the spelling ג-ל-ה in the Hebrew Bible. With the help of verbal valency theory, I examine the complementation patterns of גלה.

Previous attempts to understand the ancient Hebrew גלה focus on semantics. I challenge this approach and suggest that semantics alone is insufficient for understanding גלה (Chapter 1). Thus, I incorporate the clausal syntax of גלה with attention to גלה’s appearance in the different binyanim and the different complement patterns that accompany גלה’s different …

The Experience Of Victimization As The Result Of Cyberbullying Among College Students: A Study Of Demographics, Self-Esteem, And Locus Of Control, Sonya P. Poole

Electronic Theses and Dissertations

Cyberbullying is commonly defined as a deliberate and aggressive act that is committed using an electronic form of contact. It has been linked to negative emotional and mental well-being along with incidents of suicide. The current study looks at the prevalence rates of cyberbullying among college aged adults. It uses a survey method design to examine the correlation of cyberbullying with gender, age, race, socioeconomic status, self-esteem, and locus of control. The results indicated a relatively high report of cyberbullying incidents when compared to previous studies. A significant difference was obtained when cyberbullying incidents were evaluated based on the participant’s …

Ethnic Student Organization Leaders' Perceptions Of Institutional Diversity Efforts At A Predominantly White Faith-Based University, Kholofelo M. Theledi

Electronic Theses and Dissertations

Although student organizations have the potential to significantly contribute to the diversity efforts of predominantly White institutions (PWI), colleges continue to undermine the value of these organizations (Kuk & Banning, 2010). Ethnic student organizations, specifically the students who lead them, can play a crucial role in promoting diversity and inclusion on college campuses yet few studies examine their role in institutional diversity efforts. This study explores the perceptions of student leaders of ethnic or minority student organizations enrolled in a four year predominantly White, Christian university to better understand how they perceive their university’s diversity efforts and their own role …

Investigation Of Lattice Structures And Analysis Of Strut Geometry., Zachary D Denzik

Electronic Theses and Dissertations

This study involves the evaluation of lattice specimens fabricated using additive manufacturing as well as investigation of the influence of unit cell connection geometry. Lattice topologies of face-centered cells and body-centered cells were modeled, investigated using finite element analysis (FEA) for each specimen, manufactured using direct metal laser sintering (DMLS) with maraging steel powder, and mechanically tested. The strut diameter of each topology was altered to yield four different mass reductions from a solid cube, ranging from 55%-90% mass reduction. Three iterations of 1000mm³ lattice specimens were investigated. The first iteration consisted 0.5mm plates on the top and bottom …

Microaggressions Towards Individuals With Learning Disability Within The College Setting, Cordava Valentina Aranda

Electronic Theses and Dissertations

Abstract

Learning disability mircroaggressions refer to the everyday verbal, nonverbal, and environmental slights and mistreatment which convey a derogatory feeling or message to individuals with a learning disability across various settings. Learning disability microaggressions may contribute significantly to the negative aspects of mental health issues often perceived in individuals with learning disabilities. The purpose of this study was to develop a microaggression scale designed to assess microaggressions displayed towards individuals with learning disabilities (LD) within the academic setting. A scale designed to assess LD microaggressions was constructed and modeled after the Racial Microaggression Scale (RMAS). A confirmatory factor analysis was …

Aging-In-Place Home Modification: Led Lamp Color Temperature Preference Among Adults, Laura J. Maher Mrs.

Electronic Theses and Dissertations

This study evaluated LED color temperature preference and effectiveness in a task light setting for older adults with a comparison to younger adults. Test subjects included visually active adults, male and female, from 19 years to 96 years of age. The researcher tested one hundred participants from several test sites. The researcher ascertained conclusions based on the correlations of age, gender, visual acuity, time of day, and visual medical conditions to LED preference. A tunable lamp with four correlated color temperatures (CCT/K), 2700K, 3500K, 4100K, and 5000K was analyzed using timed and graded, reading and number comparison tasks. Lumen output …

Structural And Stratigraphic Reconstruction Of The Whiting Dome Salt Structure In Viosca Knoll-Mississippi Canyon, Gom, Using 3d Seismic Data, Matthew R. Worrell

Electronic Theses and Dissertations

Understanding the complexities of salt tectonics is one of the most important factors regarding seismic interpretation of stratigraphy, structure, and geomorphology in the Gulf of Mexico. Evaluating the processes affecting recent mobilization of salt in the shallow, well-imaged section can help provide analogues for older, similar occurrences in the deeper section, thereby providing structural models for the autochthonous salt and its effect on stratigraphy and even potential timing and migration issues of hydrocarbons.

Progradation of delta front and shelf to slope transitional sediments has expulsed and emplaced an allochthonous salt structure (Whiting Dome) in the Viosca Knoll and Mississippi Canyon …

The Relationship Of Locus Of Control And Social Learning On Academic Achievement In A Supplemental Instruction Program, Tina Fleet

Electronic Theses and Dissertations

ABSTRACT

A large number of high school students entering college are arriving academically unprepared. Abilene Christian University’s newly founded Bridge Scholars Program seeks to help and support academically at-risk students based upon low ACT/SAT scores and low high school GPA averages. This research utilizes the Supplemental Instruction program, (based upon Bandura’s social learning theory), as its academic intervention. The research questions are 1) How does Supplemental Instruction contribute to an at-risk student’s college readiness (knowledge, skills, attitudes, behaviors and strategies)? And, 2) Does a student’s internal or external locus of control predict academic performance? A pretest and posttest using Rotter’s …

Racial Socialization And Its Moderating Effects On Microaggressions, Jusiah L. Prowell

Electronic Theses and Dissertations

The purpose of this research was to examine the relationship between racial socialization, and how it mitigates the distress caused by microaggressions. Although overt racism is no longer socially acceptable, racism still occurs in a covert form called microaggressions. Research has shown that microaggressions causes negative effects on its’ victims the same as overt racism. Also, literature has shown microaggressions in the classroom and on college campuses cause feelings of isolation and inferiority in college students. Racial socialization is the process of being immersed in one’s culture to strengthen against negative factors. The construct of racial socialization is the idea …

A Systems Approach To Revenue Fluctuation In Nonprofit Human Service Organizations, Joshua James Hunter

Electronic Theses and Dissertations

Nonprofit Human Services Organizations (NPO) are normally considered to do all they can to work toward providing clients with optimal services (Bowman, 2011). What has not been considered is the possibility that NPOs sometimes allocate more revenue toward accumulating profit than toward generating services. This study used IRS 990 Forms of 150 private nonprofits from 2009 to 2010 to investigate whether NPOs did this at the peak of the recent recession, a time when there was a strong need for NPOs to increase their level of services. Results showed revenue increased 56%, services increased 1.4%, profit increased 43%, operating margin …

The Relationship Between Hospitalizations And Anxiety And Depression Symptoms In Patients With Cystic Fibrosis, Ronni T. Barker

Electronic Theses and Dissertations

In 2015, the Cystic Fibrosis (CF) Foundation collaborated with the European CF Society to develop new guidelines to screen for depression and anxiety in people with CF. The guidelines were based on a study that assessed over 6,000 patients and 4,000 caregivers among 45 centers in the United States and eight European countries. Research has proven that depression and anxiety have a negative impact on CF and overall health. 186 adolescents within the CF clinic at Children’s Health Center voluntarily completed the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7). These screenings were completed between February 2016-March 2017 and …

Weight Stigma, Cognitions, And Disordered Eating, Sarah E. Pelfrey

Electronic Theses and Dissertations

Weight stigma experiences affect people of all weights and have many negative consequences; despite this, weight stigma is still an acceptable prejudice in our society. Research has established that weight stigma is predictive of disordered eating (DE) cognitions, which are, in turn, predictive of DE behaviors. The current study explored the unique contribution DE cognitions make to DE behaviors while controlling for other DE cognitions. The DE cognitions examined in the current study were drive for thinness, weight bias internalization, and perfectionism. The DE behaviors examined were emotional eating, restrained eating, inappropriate compensatory behaviors, and binge-eating. Weight bias internalization and …

Effects Of Ponderosa Pine Ecological Restoration On Forest Soils And Understory Vegetation In Northern Arizona, Elena M. Thomas, Kenneth W. Farrish, Brian P. Oswald, Melinda G. Shaw-Faulkner, Scott R. Abella

Electronic Theses and Dissertations

The human exclusion of wildfire and overgrazing by livestock since settlement have caused dramatic changes in ponderosa pine (Pinus ponderosa Dougl ex Laws) forest ecosystems. These changes include increased numbers of tree stems, reduced understory cover and diversity, and the introduction of invasive, non-native understory species. This study evaluated the coverage and species composition of understory vegetation present in the “cool-season” (late spring and early summer) in a ponderosa pine forest on grazed and ungrazed plots that had undergone restoration treatments on three different soil/geologic parent material types near Flagstaff, Arizona, twelve years after tree thinning and grazing exclosure …

The Regulation Of Rotavirus–Infected Ht29.F8 And Ma104 Cells Treated With Arachidin 1 Or Arachidin 3, Caleb M. Witcher

Electronic Theses and Dissertations

Rotavirus (RV) infections cause severe life threatening diarrhea in young children and immunocompromised individuals. Several effective vaccines have been developed for young children but are not protective against all strains of RV, and there are no anti-RV therapeutics. Our laboratory has discovered a decrease in the number of infectious simian RV particles (SA114f) in human intestinal cell line, HT29.f8 cells with the addition of either of two stilbenoids, arachidin-1 (A1) or arachidin-3 (A3). This suggests effects on the host cell and RV replication. We examined the cellular effects of human RV strain (Wa) on a human intestinal cell line (HT29.f8) …

Examining Attrition Through The Hierarchal System Of Education For Zero - Fifth Year Teachers: A Mixed Methods Study, Joshua D. Nation

Electronic Theses and Dissertations

Teacher attrition was the focal issue of this mixed-methods study. Teachers, for a wide variety of reasons, have left the profession of education due to issues surrounding school leadership, compensation, and student behavior, just to name a few. This study intended to expand the understanding of zero through fifth year teachers, and if this population of teachers is satisfied, and staying in the field, or if they are dissatisfied. By using Bronfenbrenner’s Ecological Systems Theory, the factors within in the hierarchal educational system were explored to identify which part of the educational system is connected to teacher attrition: the microsystem, …

Gravitational Study Of The Hastings Salt Dome And Associated Faults In Brazoria And Galveston Counties,Texas, Francis C. Okocha

Electronic Theses and Dissertations

Salt domes are important geological structures because they are potential major hydrocarbon traps and have a profound effect on overlying strata in the subsurface. Over five hundred salt domes have been located on the United States Gulf Coast region, including the Hastings Salt Dome. Hastings Oil Field is located about 40.2 km (25 miles) southeast of Houston, Texas. The Hasting oil field was discovered in 1934 and it was considered the largest oil reserve on the Gulf Coast. Its peak production of 75,000 BOPD (barrels of oil per day) was recorded in 1977 and it had a cumulative production of …