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The Influence Of Self-Prescribed Knee Bracing On Walking In Healthy Adults, Lauren Luginsland Jan 2018

The Influence Of Self-Prescribed Knee Bracing On Walking In Healthy Adults, Lauren Luginsland

Electronic Theses and Dissertations

The knee is one of the most commonly loaded anatomical joints in the human body due to maintaining an upright posture. Increased joint loading can lead to various injuries which can either be treated surgically or non-surgically including immobilization by bracing. Numerous studies have looked at functional knee bracing post-operative surgery creating a gap within the literature analyzing non-operative functional knee braces within a healthy population. Commonly prescribed functional knee braces such as the Ossur Rebound® have been prescribed by physicians, but also available over-the-counter for self-prescription to assist with injury prevention, stabilization, and protection. Previous studies have looked at …


Development And Characterization Of Fluocinolone Acetonide Loaded Nanosized Lipid Carriers For Ocular Delivery Via Subconjunctival Route: Synergistic Effect Of Vitamin A Palmitate, Bhavik Soneta Jan 2018

Development And Characterization Of Fluocinolone Acetonide Loaded Nanosized Lipid Carriers For Ocular Delivery Via Subconjunctival Route: Synergistic Effect Of Vitamin A Palmitate, Bhavik Soneta

Electronic Theses and Dissertations

Though nanotechnology which exploits the use of nanoparticles for therapeutic application have embarked as an emerging tool for drug delivery applications, the delivery of therapeutic molecules into deep ocular compartments has always been a challenging task. In this regard, the main objective of our current investigation was to develop and evaluate the fluocinolone acetonide (FA) loaded nanostructure lipid carrier (FA-NLC) in situ gel for improved ocular bioavailability by subconjunctival injection. FA, a corticosteroid administered for inhibiting the ocular inflammation either as intravitreal injection or as intravitreal implants. The FA-NLCs were developed by using vitamin A palmitate as one of the …


Feasibility Of Aquasolvetm Hpmc-As Lg Via Hot-Melt Extrusion: Effect Of Pressurized Co2 On Physico-Mechanical Properties, Mashan Almutairi Jan 2018

Feasibility Of Aquasolvetm Hpmc-As Lg Via Hot-Melt Extrusion: Effect Of Pressurized Co2 On Physico-Mechanical Properties, Mashan Almutairi

Electronic Theses and Dissertations

The objective of the current study was to investigate the processability of Aquasolve™ HPMC-AS LG via hot-melt extrusion, and to examine the effect of pressurized carbon dioxide (P-CO2) on the physico-mechanical properties of Efavirenz (EFA)-loaded extrudates (EXT). EFA is as a poorly water-soluble drug and HPMC-AS LG was chosen as a carrier for this study. To optimize the process parameters and formulations, various physical mixtures were prepared with the following composition: EFA (30-40-50% w/w) and HPMC-AS LG (70-60-50 % w/w) respectively. Physical mixtures were extruded through the co-rotating twin-screw extruder (16mm Prism Euro Lab, Thermo Fisher Scientific) utilizing a standard …


Synthesis And Characterization Of Redox-Sensitive Polymer And Prodrug For Targeted Drug Delivery, Chang-Hee Whang Jan 2018

Synthesis And Characterization Of Redox-Sensitive Polymer And Prodrug For Targeted Drug Delivery, Chang-Hee Whang

Electronic Theses and Dissertations

Systemic administration of chemotherapeutics is associated with various side effects deriving from accumulation in off-target sites and acute toxicity of the drugs. In the past decade, engineering targeted drug delivery platforms arose as a novel paradigm to overcome such obstacles and ultimately achieve advanced forms of chemotherapy. This thesis reports successful syntheses of l-RSP, a redox-sensitive self-immolative polymer, and DNS-SN38, thiol-sensitive SN-38 prodrug, as potential candidates for targeted drug delivery platforms. By covalently conjugating a redox-trigger (p-nitrobenzyl alcohol) and self-immolative linker (p-hydroxybenzyl alcohol) to the cyclization spacer (n-2-(hydroxyethyl)ethylene diamine), a novel self-immolative monomer was obtained. Polymerization of the respective monomer …


Crystalline Salt Formation Of An Acidic Drug Indomethacin Using Hot Melt Extrusion Technology, Mustafa Bookwala Jan 2018

Crystalline Salt Formation Of An Acidic Drug Indomethacin Using Hot Melt Extrusion Technology, Mustafa Bookwala

Electronic Theses and Dissertations

Although salt formation is the most ubiquitous and effective method of increasing the solubility and dissolution rates of acidic and basic drugs, it consumes large quantities of organic solvents and is a batch process. Herein, we show that the dissolution rate of indomethacin (a poorly water-soluble drug) can be increased by using hot melt extrusion of a 1:1 (mol/mol) indomethacin:tromethamine mixture to form a highly crystalline salt, the physicochemical properties of which are investigated in detail. Specifically, pH–solubility studies demonstrated that this salt exhibited a maximal solubility of 19.34 mg/mL (>1000 times that of pure indomethacin) at pH 8.19. …


A Church Adrift: Virginia's Church Of England, 1607-1677, Katherine Gray Blank Jan 2018

A Church Adrift: Virginia's Church Of England, 1607-1677, Katherine Gray Blank

Electronic Theses and Dissertations

The Church of England in the Virginia colony is an institution which has been much overlooked in historiography. Traditionally, historians have focused upon the weakness of the church, with its lack of a complete hierarchy and dearth of ministers. These weaknesses, combined with some of the more unsavory attitudes and actions of early colonists, have led many scholars to postulate that religion did not play much of a role in the Virginia colony. While the early colonists did struggle, and the church was weak, historians have overlooked the fact that most Virginians were seventeenth-century Englishmen, and inhabited a world that …


A Comparison Of Energy Expenditure And Prediction Equations During Walking Or Running Corrected For One Mile In Normal Weight And Overweight African American, Asian, And Caucasian Adults And Cross-Validation Of The Equations, Xi Jin Jan 2018

A Comparison Of Energy Expenditure And Prediction Equations During Walking Or Running Corrected For One Mile In Normal Weight And Overweight African American, Asian, And Caucasian Adults And Cross-Validation Of The Equations, Xi Jin

Electronic Theses and Dissertations

The prevalence of obesity is rapid across the world. Knowledge of the actual energy expenditure (EE) of walking and running can lead to a more precise exercise prescription which may lead to an obesity reduction or avoidance. Limited research has focused on EE during walking and running. Therefore, the aims of this study included developing ethnic based cross validated EE prediction equations for African American, Asian and Caucasian adults, and a multiple regression equation developed that included all three ethnic groups. Also, the energy expenditure among these three ethnic groups was compared. A total of 224 subjects, including 71 Caucasians, …


How Do Specialist Expertise, Auditor-Specialist Communication, And Time Pressure Affect Auditors’ Use Of Specialists’ Valuations?, Sara Gochnauer Jan 2018

How Do Specialist Expertise, Auditor-Specialist Communication, And Time Pressure Affect Auditors’ Use Of Specialists’ Valuations?, Sara Gochnauer

Electronic Theses and Dissertations

This study experimentally investigates auditors’ reliance on specialists’ work regarding complex estimates. Specifically, this paper examines how the relevance of specialists’ expertise (or the degree to which their prior experience matches the current task), the opportunity for auditor-specialist pairs to communicate, and the level of time pressure affect the extent to which auditors rely on specialists’ estimates. To investigate the research question, I employ a mixed experimental design in an abstract setting, where college students take on the roles of auditor and specialist and work in auditor-specialist pairs to complete an estimation task. I manipulate the relevance of specialists' expertise …


Excess Zeros, Endogenous Binary Indicators, And Self-Selection Bias With Application To First Marriage, Smoking And Drinking Outcomes, Lateef Subair Jan 2018

Excess Zeros, Endogenous Binary Indicators, And Self-Selection Bias With Application To First Marriage, Smoking And Drinking Outcomes, Lateef Subair

Electronic Theses and Dissertations

No abstract provided.


L2 Teachers' Efficacy: The Impact Of Professional Development, Nino Jakhaia Jan 2018

L2 Teachers' Efficacy: The Impact Of Professional Development, Nino Jakhaia

Electronic Theses and Dissertations

This quasi-experimental explanatory sequential mixed-methods study examined the impact of a 25-hour professional development on English as a foreign language (L2) teachers’ sense of efficacy in writing instruction in the country of Georgia. It also explored the links between teachers’ beliefs about teaching writing, self-efficacies in instructional strategies, and the professional development. A convenience sampling technique was used to select teachers for participation in the professional development. The quantitative data was collected through the teacher efficacy scale. The qualitative methods in the form of semi-structured questions about efficacy were used to enhance the data by examining teachers’ perceptions of the …


Mississippians In Physics: Perspectives And Practice In A Search For Physics Excellence, Paul D. Rogers Jan 2018

Mississippians In Physics: Perspectives And Practice In A Search For Physics Excellence, Paul D. Rogers

Electronic Theses and Dissertations

This mixed-method study represents a broad evaluation of the physics views of Mississippi physics students and physicists, along with an analysis of graduate school data, in a search for answers which might improve physics education in Mississippi. Descriptive statistics were calculated using data from eight graduate degree programs (from Fall 2003 through Full Summer 2012) at the University of Mississippi. This was done to find the percent of graduate degrees in each degree program which were awarded to in-state residents. It was found that of the eight University of Mississippi graduate degree programs in the study, two programs awarded a …


How Newspapers In China, India And Bangladesh Framed The Rohingya Crisis Of 2017, Md Khadimul Islam Jan 2018

How Newspapers In China, India And Bangladesh Framed The Rohingya Crisis Of 2017, Md Khadimul Islam

Electronic Theses and Dissertations

The Rohingya persecution in Myanmar’s Rakhine state in 2017 attracted intense international media attention. In light of normative theory, media of different countries are assumed to cover an issue differently because of differences in the socio-political systems involved. This study examines how media from three different countries framed the Rohingya Muslim issue. These systematic and qualitative content analyses of six newspapers from three neighboring countries — China, India and Bangladesh — examines media framing of Myanmar in light of Robinson’s (2001) Policy-Media Interaction model. The timeframe of the study was one month, starting on the first day of Myanmar’s Rohingya …


Small Batch: Women's Positions In Southern Craft Beverages, Victoria De Leone Jan 2018

Small Batch: Women's Positions In Southern Craft Beverages, Victoria De Leone

Electronic Theses and Dissertations

This thesis explores three different forms of narrative in order to understand how and why craft beverage industries, specifically beer and whiskey, have been framed as masculine spaces. Women who seek to work in or around these industries are often sorted into the marketing, sales and service corners of the industry, and the production floor still hosts very few women, and those women must negotiate performing their femininity and the masculinities deemed necessary for the environment simultaneously. I argue that the way that we talk about women who choose to do this work is rooted in a history of domestic …


A Righteousness Housed In The Body: The Conception And Division Of Kings' Bodies In Early Medieval Northwestern Literature, Sharon Miller Wofford Jan 2018

A Righteousness Housed In The Body: The Conception And Division Of Kings' Bodies In Early Medieval Northwestern Literature, Sharon Miller Wofford

Electronic Theses and Dissertations

This thesis examines how the bodies of kings in medieval Irish, Anglo-Saxon, and Norse literature demonstrate sacral kingship, a theory which links the prosperity of a people to the strength of the king’s relationship with the divine. I argue that the practice of collecting the heads of English kings as relics, particularly the Northumbrian warrior-kings Edwin and Oswald, is due to an understanding of the king's bodies as a source of power and "luck." I put the dispersal of the heads of Kings Edwin and Oswald in conversation with the work of Andrew Reynolds on deviant burial customs in Anglo-Saxon …


Home Is Where The Hot Tamale Is: Rediscovering The Delta, Georgia Corinne Clarke Jan 2018

Home Is Where The Hot Tamale Is: Rediscovering The Delta, Georgia Corinne Clarke

Electronic Theses and Dissertations

This thesis project is an in-depth personal exploration of the hot tamale in the Mississippi Delta, presented in a long-form magazine piece. It analyzes the cultural exchange that brought the hot tamale to the region in the early 20th century, its racial representation in the Delta, and its future as chefs across the nation seek to interpret the regional cuisine. Further, this thesis analyzes the hot tamale’s components that tell why and how the hot tamale became a staple, and the story of hardship and discrimination that it symbolizes. Traveling through my own past, this piece reflects the interactions that …


Perceptions Of University Students Toward Bilingualism In Fribourg, Barcelona, And Oxford, Madison Densmore Jan 2018

Perceptions Of University Students Toward Bilingualism In Fribourg, Barcelona, And Oxford, Madison Densmore

Electronic Theses and Dissertations

This master's thesis explores university students’ perceptions toward bilingualism and foreign language teaching in two bilingual, European communities—Fribourg, Switzerland, and Barcelona, Spain—and at the University of Mississippi in monolingual-dominant Oxford, Mississippi. This research was conducted over a period of about nine months and includes both qualitative and quantitative data: twenty-four interviews as well as three online questionnaires which were made available in the following five languages: French, German, Catalan, Castilian Spanish, and English. During the interviews and on the Qualtrics questionnaires, students were asked to share their perceptions about language, their communities, and foreign language teaching. For clarity purposes, although …


Marketing The Myth: The Racial Commodification And Reclaiming Of Aunt Jemima, Holly Robinson Jan 2018

Marketing The Myth: The Racial Commodification And Reclaiming Of Aunt Jemima, Holly Robinson

Electronic Theses and Dissertations

Through an analysis of print advertisements and of research gathered at the Jim Crow Museum of Racial Memorabilia, this thesis intends to explore how the Aunt Jemima brand from the early 1890’s to the present day has utilized multiple marketing strategies in order to garner consumer attention. Focusing specifically on Karen Cox’s notion of the “southern tableau,” M. M. Manring’s investment in Aunt Jemima as a Slave in A Box, and Patricia Yaeger’s theory of the “throwaway body,” this thesis will look at how elements of print advertising, the Aunt Jemima pancake-box, and racist memorabilia intersect. In order to experiment …


A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu Jan 2018

A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu

Electronic Theses and Dissertations

People suffer dysphagia when swallowing hard tablets and capsules. Gelatin based soft chewable tablets was used as an alternative and novel drug delivery format to overcome dysphagia. But conventional method of producing gelatin based soft chewable tablets has many potential issues. The objective of this study is using glycerol and hot-melt extrusion technique to address potential issues and optimizing the formulation. Gelatin (15%), acetaminophen (30%), saccharin (1.5%), xylitol (6.5%), sodium chloride (2%) and six different ratios of water (45-0%) and glycerol (0-45%) were used in seven formulations. The extrusion process temperature of formulation 1-6 and formulation 7 were 90 ëšc …


A Song Of Confusion And Annoyance: Kant On The Beauty Of Absolute Music, Ryan Walton Turner Jan 2018

A Song Of Confusion And Annoyance: Kant On The Beauty Of Absolute Music, Ryan Walton Turner

Electronic Theses and Dissertations

Kant's evaluation of music in the Critique of Judgement stands as a blemish on an otherwise appealing system of judgments of beauty and of assigning aesthetic worth. In order to resolve this tension, I will present an argument in three parts. First, I will delve further into Kantian judgments of beauty to provide solid contextual grounds for why he draws his conclusions about music and will further elaborate on his various positions concerning music. Second, I will look at a few potential answers for the problem of music given by others in the philosophy of music and briefly evaluate their …


A Teleosemantic Theory Of The Deep-Unconscious: A Response To John R. Searle's Account Of The Unconscious, Kelly Adkins Jan 2018

A Teleosemantic Theory Of The Deep-Unconscious: A Response To John R. Searle's Account Of The Unconscious, Kelly Adkins

Electronic Theses and Dissertations

In mind, John R. Searle dismisses the deep-unconscious on the grounds that it neither satisfies the connection principle nor does it exhibit intentionality. I argue against Searle's account of the unconscious. My initial reason for rejecting Searle's account is that he sacrifices the theoretical virof explanatory power for the sake of ontological simplicity. The reason the unconscious mind gained theoretical sustenance in the first place was to understand and explain various aspects of human behavior that consciousness cannot account for, so any good theory of the unconscious ought to fill this explanatory gap. By oversimplifying the unconscious, Searle's account cannot …


Abstinence Based Sex Education: A Mixed-Method Evaluation Of Experiences With And The Effectiveness Of Sex Education In The Deep South, Heather Costa-Greger Jan 2018

Abstinence Based Sex Education: A Mixed-Method Evaluation Of Experiences With And The Effectiveness Of Sex Education In The Deep South, Heather Costa-Greger

Electronic Theses and Dissertations

This project examines the effectiveness of federally funded, abstinence-based sex education programs. It evaluates students' experiences with sex education programs that have been, in some cases, proven to provide medically inaccurate information. Using a mixed-method online survey, this study focuses on undergraduate college students in Sociology 101 courses at the University of Mississippi. The online survey, which has both quantitative and qualitative elements that assess students' sex education experience, what they remember being taught and what they wish they would have been taught. The results of the study highlight important shortcomings in current sex education programs in the deep south, …


Reflectance Transformation Imaging: Documenting Graffiti In The Maya Lowlands, Rachel Gill Jan 2018

Reflectance Transformation Imaging: Documenting Graffiti In The Maya Lowlands, Rachel Gill

Electronic Theses and Dissertations

In the late 19th century, explorers identified graffiti etched in stucco walls of residences, palaces, and temples in the Maya Lowlands. By the mid-20th century, scholars acknowledged that the ancient Maya produced these incised images. Today, archaeologists struggle with documenting these instances of graffiti with precision and accuracy, often relying solely on to-scale line drawings to best represent the graffitied image they see before them. These images can be complex, multilayered, and difficult to see so identifying the sequence of creation of the incisions can be challenging. Reflectance Transformation Imaging (RTI) is a method that uses a moving light source …


A Complex Calculus: How Message Format And Processing Route Coordinate To Influence Hpv Vaccination Message Persuasiveness Among Young Adults, Laura Boutemen Jan 2018

A Complex Calculus: How Message Format And Processing Route Coordinate To Influence Hpv Vaccination Message Persuasiveness Among Young Adults, Laura Boutemen

Electronic Theses and Dissertations

Human papillomavirus (HPV) infection may lead to cancer and genital warts yet can be prevented by a safe and effective vaccine recommended for individuals up to 26 years old. HPV vaccination rates remain low among college aged adults that represent a catch-up population still eligible to receive the HPV vaccine. This present study is a theory-based investigation employing the Heuristic Systematic Model to explore the effect of message format and processing route on attitude and behavioral intention in the context of HPV vaccination. Undergraduate students aged 17-26 years old (N = 261) from various majors (e.g., STEM, social sciences, humanities) …


Holding Off On The Fun Stuff: Academic Media Multitasking And Binge Watching Among College Students, Kelly Merrill Jr. Jan 2018

Holding Off On The Fun Stuff: Academic Media Multitasking And Binge Watching Among College Students, Kelly Merrill Jr.

Electronic Theses and Dissertations

College students are often faced with the temptation of engaging in academic media multitasking and binge watching or completing their academic coursework in a timely and effective manner. A quantitative survey (N = 651) explored trait individual differences in self-control and academic delay of gratification and situational individual differences in enjoyment, reward, procrastination, regret, and guilt as predictors of academic media multitasking frequency, binge watching frequency, and binge watching duration. Stepwise regressions reveal that self-control is not a predictor of these media behaviors, while age and greater enjoyment were the only predictors of academic media multitasking and gender and greater …


Masquerading Techniques In Ieee 802.11 Wireless Local Area Networks, Omar Nakhila Jan 2018

Masquerading Techniques In Ieee 802.11 Wireless Local Area Networks, Omar Nakhila

Electronic Theses and Dissertations

The airborne nature of wireless transmission offers a potential target for attackers to compromise IEEE 802.11 Wireless Local Area Network (WLAN). In this dissertation, we explore the current WLAN security threats and their corresponding defense solutions. In our study, we divide WLAN vulnerabilities into two aspects, client, and administrator. The client-side vulnerability investigation is based on examining the Evil Twin Attack (ETA) while our administrator side research targets Wi-Fi Protected Access II (WPA2). Three novel techniques have been presented to detect ETA. The detection methods are based on (1) creating a secure connection to a remote server to detect the …


Mechanism Design Of A Compact 4-Dof Robotic Needle Guide For Mri-Guided Prostate Intervention, Shihao Zhang Jan 2018

Mechanism Design Of A Compact 4-Dof Robotic Needle Guide For Mri-Guided Prostate Intervention, Shihao Zhang

Electronic Theses and Dissertations

In the past several MRI compatible robotic needle guide devices for targeted prostate biopsy have been developed. The large and complex structure have been identified as the major limitations of those devices. Such limitations, in addition to complex steps for device to image registration have prevented widespread implementation of MRI-guided prostate biopsy despite the advantages of MRI compared to TRUS. We have designed a compact MRI-guided robotic intervention with the capability to have angulated insertion to avoid damage to any anatomical feature along the needle path. The system consists of a novel mechanism driven Robotic Needle Guide (RNG). The RNG …


A Phenomenological Study Of The Experiences Of Successful Women In Science Fields, Jonathan Hall Jan 2018

A Phenomenological Study Of The Experiences Of Successful Women In Science Fields, Jonathan Hall

Electronic Theses and Dissertations

Girls and women face several forms of gender-based biases and discrimination in the science community. These issues create difficult circumstances for them to develop positive science identities. Since these difficult circumstances exist, science education and sociology researchers have used a deficit model to learn about their experiences, achievements, and attitudes. Understanding the experiences of successful women in science offers insight into how women can navigate the challenges presented by the science community and how science educators can support them. However, research studies that explore the experiences of successful women in science are scant. Therefore, the objective of this study was …


An Analysis Of The Preparedness Of Educational Institutions To Ensure The Security Of Their Institutional Information, Vikram Ahmed Jan 2018

An Analysis Of The Preparedness Of Educational Institutions To Ensure The Security Of Their Institutional Information, Vikram Ahmed

Electronic Theses and Dissertations

The purpose of this exploratory study was to analyze and examine the differences in the preparedness of educational institutions toward ensuring the security of their data by comparing their self-reported perceptions of security risks and their assessments of the corresponding risk-mitigating practices. Factors that were studied with reference to securing institutional data were aligned with the five components of information systems: hardware, software, data, procedures and people. The study examined the perceptions of security threats associated with these factors and explored the perceptions of the effectiveness of critical measures with respect to these factors within the constraints applicable to educational …


A Digital Media Exploration Of The Federal Writers' Project's Folk Song Collecting Expeditions In Depression Era Florida, Holly Baker Jan 2018

A Digital Media Exploration Of The Federal Writers' Project's Folk Song Collecting Expeditions In Depression Era Florida, Holly Baker

Electronic Theses and Dissertations

This digital thesis project examines the folk song collecting expeditions of the Federal Writers' Project (FWP) in Florida between 1935 and 1942. The FWP carried out numerous folk music collecting expeditions in Florida through the Works Progress Administration. Folklorists such as Zora Neale Hurston, Alan Lomax, and Stetson Kennedy led the expeditions and traveled throughout Florida to record blues, "jook" songs, work songs, and traditional music from African American, Cuban, Czech, Greek, Minorcan, Seminole, and Slavic communities. While romantic notions of nationalism in the 1930s often promoted homogenization, the FWP emphasized inclusiveness and highlighted cultural diversity. The FWP's approach challenged …


In Quest Of Bernstein Inequalities Rational Functions, Askey-Wilson Operator, And Summation Identities For Entire Functions, Rajitha Puwakgolle Gedara Jan 2018

In Quest Of Bernstein Inequalities Rational Functions, Askey-Wilson Operator, And Summation Identities For Entire Functions, Rajitha Puwakgolle Gedara

Electronic Theses and Dissertations

The title of the dissertation gives an indication of the material involved with the connecting thread throughout being the classical Bernstein inequality (and its variants), which provides an estimate to the size of the derivative of a given polynomial on a prescribed set in the complex plane, relative to the size of the polynomial itself on the same set. Chapters 1 and 2 lay the foundation for the dissertation. In Chapter 1, we introduce the notations and terminology that will be used throughout. Also a brief historical recount is given on the origin of the Bernstein inequality, which dated back …