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Data Governance Maturity, Ai Integration, And Equity In Colorado K-12 Public Schools, John R. Curtin Jun 2026

Data Governance Maturity, Ai Integration, And Equity In Colorado K-12 Public Schools, John R. Curtin

Electronic Theses and Dissertations

Colorado's 179 K-12 public school districts operate as autonomous governance units, each responsible for securing and managing student data assets that span health, financial, residential, and academic records. The accelerating integration of artificial intelligence (AI) and machine learning (ML) tools into administrative workflows, productivity software, and instructional platforms has fundamentally altered the risk landscape for student data, yet governance frameworks at the state, district, and school levels have not kept pace. This dissertation investigates whether Colorado's decentralized educational governance structure is institutionally capable of producing equitable, secure, and sustainable data governance outcomes in the AI era.

Drawing on Institutional Theory …


Evaluation And Distillation Of Source Code Generation Tasks By Large Language Models, Danny Brahman Jun 2026

Evaluation And Distillation Of Source Code Generation Tasks By Large Language Models, Danny Brahman

Electronic Theses and Dissertations

Large Language Models (LLMs) are predominantly assessed based on their common sense reasoning, language comprehension, and logical reasoning abilities. While models trained in specialized domains like mathematics or coding have demonstrated remarkable advancements in logical reasoning, there remains a significant gap in evaluating their code generation capabilities. Existing benchmark datasets fall short in pinpointing specific strengths and weaknesses, impeding targeted enhancements in models’ reasoning abilities to synthesize code.

To bridge this gap, this thesis introduces two novel contributions: CodeEval and CodeQual. CodeEval is an innovative, pedagogical benchmarking method that mirrors the evaluation processes encountered in academic programming courses. It comprises …


The Organizational Experience Of Next Gen Learning Through Portrait Of A Graduate, Kathleen J. Campbell Jun 2026

The Organizational Experience Of Next Gen Learning Through Portrait Of A Graduate, Kathleen J. Campbell

Electronic Theses and Dissertations

This qualitative single-case study investigates the organizational journey of navigating the complexities of systemic transformation. In 2021, Silver Peak School District (SPSD; a pseudonym), a rural educational organization in the western United States, implemented a graduate competency framework known as Portrait of a Graduate. This study analyzed the experiences of teachers, instructional coaches, and principals with the explicit Portrait policies, practices, and resource flows of five learning structures—graduate competencies (in SPSD, this is analogous to Portrait), deeper learning, agency, performance assessment, and teaching culture—in a district in the messy middle of Portrait adoption. By focusing on a district situated in …


She Believed She Could, So She Did: A Lifecycle Approach To Understanding Leadership And Self-Efficacy Development In Women Astronauts, Savanah Faith Sellars Bray Jun 2026

She Believed She Could, So She Did: A Lifecycle Approach To Understanding Leadership And Self-Efficacy Development In Women Astronauts, Savanah Faith Sellars Bray

Electronic Theses and Dissertations

This dissertation examines how women leaders develop and sustain self-efficacy, and develop as leaders, throughout their lives. Although decades of research document the barriers women face navigating leadership journeys, including the challenges described in the Women’s Leadership Labyrinth of prejudice, discrimination, and childcare issues, existing literature offers limited insight into how women actively build belief in their capacity to lead and accomplish their goals. Further, research consistently shows that women report lower leadership self-efficacy than men, even with comparable experience, yet the developmental processes that shape this gap, beginning in childhood, remain underexplored. Guided by self-efficacy research and its four …


Defying Impossibility: Critical Qualitative Reorientations To Black Lgbtqia+ Sense Of Belonging, Olivia H. Hunte Jun 2026

Defying Impossibility: Critical Qualitative Reorientations To Black Lgbtqia+ Sense Of Belonging, Olivia H. Hunte

Electronic Theses and Dissertations

Belonging is a human need central to survival and can be cultivated within all spheres of life. Social environments are vital for experiencing a sense of belonging. In some social environments, Black LGBTQIA+ people encounter greater impediments to their daily lives with consequences for survival, including threatening their belonging needs. Within the United States, systems of oppression create and inform conditions within social environments that can potentially thwart pathways to belonging for Black LGBTQIA+ people. Thus, fulfillment of belonging needs for Black LGBTQIA+ people is one of nuance, pain, resilience, hope, harm, trauma, resistance, and healing; scant research is available …


Higher Education Institutions In U.S. Blockchain Innovation Governance Documents, Clarissa Terracciano Jun 2026

Higher Education Institutions In U.S. Blockchain Innovation Governance Documents, Clarissa Terracciano

Electronic Theses and Dissertations

Blockchain technologies have attracted growing attention as an evolution of digital recordkeeping, prompting interest in higher education governance, credentialing, and data management. Yet, no systematic analysis exists on how U.S. government blockchain documents define institutional roles and governance authority within higher education institutions. As the national blockchain innovation system expands through governance infrastructure, the inclusion of higher education institutions as governing actors is imperative for coherent and equitable deployment. This qualitative study examines what roles the U.S. government blockchain documents assign to higher education institutions within the national blockchain innovation system.

Using innovation systems theory, particularly the triple-helix model of …


Voice And Choice: Exploring The Role Of Student Agency In High School Math Course Placement, Anne Patia Carpenter Sterry Jun 2026

Voice And Choice: Exploring The Role Of Student Agency In High School Math Course Placement, Anne Patia Carpenter Sterry

Electronic Theses and Dissertations

This study examined how students make sense of the mathematics placement process within a high-rigor independent school. In contexts where placement decisions shape access to advanced coursework, students’ interpretations of these decisions may influence both their academic trajectories and their developing mathematical identities. The purpose of this qualitative bounded case study was to understand the experiences of students who enrolled in mathematics courses that differed from placement recommendations, focusing on their motivations for self-selection, their interpretations of feedback from adults and peers, and how these experiences shaped their mathematical identities.

Data were collected through semi-structured interviews with 10 high school …


African American Business Owners' Descriptions Of Experiences With Lending Practices, Wannika R. Muhammad Jun 2026

African American Business Owners' Descriptions Of Experiences With Lending Practices, Wannika R. Muhammad

Electronic Theses and Dissertations

Entrepreneurship has remained an influential and unfulfilled goal for African Americans from the 1800s until now. Due to barriers in lending practices, increased business retention rates for African American business owners still need to be achieved. The lack of credit and lending resources hinders business growth and retention. Although Black-owned firms contribute significantly to the U.S. economy, they remain classified as underutilized entities that benefit the least, without adequate access to financial services, such as banking and lending opportunities. This study’s participants consisted of 12–15 African American business owners in central Texas, through a qualitative descriptive exploration of their experiences …


Developing An Effective Integrated Marketing Communication Game Plan For Today’S Consumers: Examining Marketing Methods That Work And How To Make The Proper Strategy Adjustments To Remain Relevant In The Future, Michele M. Wisnesck May 2026

Developing An Effective Integrated Marketing Communication Game Plan For Today’S Consumers: Examining Marketing Methods That Work And How To Make The Proper Strategy Adjustments To Remain Relevant In The Future, Michele M. Wisnesck

Electronic Theses and Dissertations

As a seasoned marketing professional, I’ve seen marketing trends and gimmicks come and go, but more critically, I’ve seen consumers shift their behavior in significant ways. The guiding research question for this project asks: With the constantly evolving marketing and consumer landscape and regular use of AI agents like ChatGPT or Google Gemini, how can marketing and communication professionals remain relevant? In short, the answer to this question is that integrated marketing communication (IMC) practitioners must adapt to ongoing consumer behavior changes brought on by technology advancements while leveraging a combination of traditional persuasive techniques, a variety of modern marketing …


The African American Pulpit And The Reconstruction Of Narrative Ground In The Black Community, Nathaniel Cox May 2026

The African American Pulpit And The Reconstruction Of Narrative Ground In The Black Community, Nathaniel Cox

Electronic Theses and Dissertations

This dissertation explores how the African American pulpit serves as a living wellspring for rebuilding stories, memory, and identity, a task made urgent by centuries of erasure, from the trauma of the Middle Passage to the ongoing reverberations of that violence. My central claim is that African American preaching, when viewed through the insight-rich frameworks of Gadamer, Burke, and Frankl, becomes not just a form of speech, but a lifeline. It helps reclaim "narrative ground": the deep roots of meaning, belonging, and shared purpose that nourish a wounded people and allow genuine flourishing.

The journey unfolds across six movements. Chapter …


Navigating Barriers: The Career Challenges Of Chinese Non-Stem Graduates In The U.S. Job Market, Dilin Li May 2026

Navigating Barriers: The Career Challenges Of Chinese Non-Stem Graduates In The U.S. Job Market, Dilin Li

Electronic Theses and Dissertations

This qualitative phenomenological study explored the career challenges faced by Chinese international graduates from non-STEM fields as they transition from U.S. higher education to the job market. While prior research has largely focused on STEM graduates who benefit from favorable visa policies and high labor demand, limited attention has been given to non-STEM students navigating structural, cultural, and social barriers to employment. Guided by the intellectual capital framework—which encompasses human, cultural, and social capital—this study examined how Chinese non-STEM graduates experience and respond to these barriers within the intersecting contexts of immigration policy, labor market expectations, and cultural adaptation.

Five …


The Ethical Imperative Of Public Health Institutions To Protect The Reproductive Autonomy Of Vulnerable Populations, Kennethea Wilson May 2026

The Ethical Imperative Of Public Health Institutions To Protect The Reproductive Autonomy Of Vulnerable Populations, Kennethea Wilson

Electronic Theses and Dissertations

This dissertation establishes the ethical responsibility of public health institutions to safeguard reproductive autonomy, especially among vulnerable populations. While reproductive decision-making is traditionally framed within individual clinical encounters, this work contends that reproductive autonomy is fundamentally a matter of public health ethics. Socioecological determinants, including social, legal, environmental, and structural factors, often constrain individuals’ ability to make meaningful reproductive choices, leading to preventable harm.

Reproductive autonomy is defined as the capacity to make informed decisions about whether and when to conceive, as well as how to parent. The dissertation critiques the sufficiency of clinical ethics frameworks, such as informed consent …


Empowering Futures: An Examination Of Educator Perceptions In Supporting Students With Disabilities In Post-Secondary Transition, Carlinda J. Spehar-Shaw May 2026

Empowering Futures: An Examination Of Educator Perceptions In Supporting Students With Disabilities In Post-Secondary Transition, Carlinda J. Spehar-Shaw

Electronic Theses and Dissertations

The purpose of this phenomenological qualitative study was to examine educators' perceptions of their roles in students' post-secondary transition. Federal mandates require special education teachers to be key components in supporting students during this process. The literature examines the multifaceted components of the transition process, including Kohler’s Taxonomy 2.0 and Schlossberg’s Transition Framework.

Data were collected using a one-on-one, semi-structured interview protocol to examine educators' perceptions of their roles in students' post-secondary transition. This strategy allowed the researcher to understand the participants' backgrounds and experiences while analyzing perceptions of their role in the post-secondary transition. A pre-designed set of interview …


Post-Vote Tampering In Nigerian Elections And The Role Of Blockchain-Enabled Electoral Systems, Ransome Chukwubuikem Enechukwu May 2026

Post-Vote Tampering In Nigerian Elections And The Role Of Blockchain-Enabled Electoral Systems, Ransome Chukwubuikem Enechukwu

Electronic Theses and Dissertations

Post-vote tampering during the collation and transmission of election results remains a persistent challenge in Nigerian elections, enabling manipulation of already-cast votes and weakening public trust in electoral outcomes. Existing technological interventions, including biometric voter accreditation and digital result transmission systems, improve voter authentication but do not adequately secure the post-vote result collation process. This thesis proposes a blockchain-enabled framework designed to protect the integrity of election results during the collation and transmission stages. Using a Design Science Research methodology, the study develops a permissioned blockchain framework based on Hyperledger Fabric that records polling-unit results as immutable ledger entries and …


Adsorption Of Pfas On Bridged Functionalized Organosilica Materials, Elisha Lawerh Kabutey May 2026

Adsorption Of Pfas On Bridged Functionalized Organosilica Materials, Elisha Lawerh Kabutey

Electronic Theses and Dissertations

PFAS are hazardous contaminants that have a devastating impact on human health and the environment. Their hazardous nature has led to the development of various adsorption methods for removing these contaminants from water sources. In this study, functionalized organosilica materials were synthesized from bis[3-(trimethoxysilyl)propyl] amine using the sol-gel method. The surface amino groups of the organosilica were converted into amine hydrochloride groups. Their adsorption properties were evaluated using salts of perfluorooctanoic acid, perfluorooctanesulfonic acid, and perfluorobutanesulfonic acid. Results showed excellent adsorption capacity of the materials. Adsorption of PFAS leads to particle agglomeration and flotation of the spent material. A column …


Atmospheric Remote Sensing Using X-Band Radar In The Marine Atmospheric Surface Layer, Daniel P. Greenway May 2026

Atmospheric Remote Sensing Using X-Band Radar In The Marine Atmospheric Surface Layer, Daniel P. Greenway

Electronic Theses and Dissertations

Atmospheric remote sensors have always offered promising technological advancements for measuring atmospheric properties over large spatial areas at high spatiotemporal resolution – a feat not currently possible with present atmospheric measurement technologies. However, remote sensors do not measure these atmospheric properties directly; they rely on robust calibrations or conversions, complex mathematical inversion methods, and/or machine learning to retrieve these properties. These inverse methods rely on the selection of an objective function, a machine learning technique, and an accurate parameterization for atmospheric property estimation. By leveraging inverse methods to improve the characterization of properties measured by remote sensors, this work enables …


Federated Learning And Blockchain-Enabled Framework For Secure And Intelligent Healthcare Systems, Jerina Eda May 2026

Federated Learning And Blockchain-Enabled Framework For Secure And Intelligent Healthcare Systems, Jerina Eda

Electronic Theses and Dissertations

Artificial Intelligence is transforming healthcare delivery, particularly in chronic disease management and patient monitoring. However, significant challenges remain in ensuring data privacy, system security, and reliable real-time monitoring while maintaining diagnostic accuracy. This thesis presents a comprehensive investigation into secure, decentralized, and intelligent healthcare systems through three interconnected research contributions addressing these critical challenges.

First, we conduct a comprehensive survey of AI applications across major healthcare domains including Chronic Kidney Disease, Diabetes Mellitus, Cardiovascular Disease, and cancer. Through systematic review of over 150 studies published between 2017 and 2024, we examine how machine learning techniques are applied to diverse medical …


Ccr5 Sulfopeptide Library And O-Glycosylated Amino Acids As Chemical Tools For Probing Chemokine Receptor Recognition, Mostafa Mohammed Mohammed Ali Eldeen May 2026

Ccr5 Sulfopeptide Library And O-Glycosylated Amino Acids As Chemical Tools For Probing Chemokine Receptor Recognition, Mostafa Mohammed Mohammed Ali Eldeen

Electronic Theses and Dissertations

Chemokine-receptor interactions play a central role in immune regulation and disease pathogenesis, particularly through CCR5, a receptor engaged by chemokines such as CCL3, CCL4, and CCL5. Post-translational modifications of the CCR5 N-terminus—including tyrosine sulfation at positions 3, 10, 14, and 15, and O-glycosylation at serine 6—critically modulate chemokine recognition and selectivity. However, the impact of specific sulfation patterns on chemokine binding and the synergistic effects of combined sulfation and glycosylation remain incompletely understood. This thesis presents a two-project chemical approach to systematically investigate CCR5 post-translational modifications. In Project 1, a comprehensive 16-member library of CCR5???? sulfopeptides representing all possible combinations …


Study Of Binary Hypothesis Testing Using Deep Learning, Sadhana Geddam May 2026

Study Of Binary Hypothesis Testing Using Deep Learning, Sadhana Geddam

Electronic Theses and Dissertations

Binary hypothesis testing is a fundamental problem in statistical signal processing and decision theory, with applications in communications, radar systems, and distributed sensor networks. Classical approaches, particularly the likelihood ratio test (LRT), provide optimal detection performance when the underlying probability distributions are known. However, in many practical scenarios, the resulting decision rules can become analytically complex or computationally intensive, especially in multi-sensor and dependent data settings.

This thesis investigates the use of neural networks for binary hypothesis testing under diverse statistical conditions. A data-driven framework is developed to learn decision rules directly from observed data, enabling the approximation of likelihood …


Semantically Grounded Evaluation For Open-Vocabulary Human-Object Interaction Detection, Maja Noack May 2026

Semantically Grounded Evaluation For Open-Vocabulary Human-Object Interaction Detection, Maja Noack

Electronic Theses and Dissertations

Open-vocabulary human–object interaction (HOI) detection is a step towards building scal¬able systems that generalize to unseen interactions in real-world scenarios and support grounded multimodal systems that reason about human–object relationships. However, stan¬dard evaluation metrics, such as mean Average Precision (mAP), treat HOI classes as dis¬crete categorical labels and fail to credit semantically valid but lexically different predictions (e.g., “lean on couch” vs. “sit on couch”), limiting their applicability for evaluating open-vocabulary predictions that go beyond any predefined set of HOI labels. I introduce SHOE (Semantic HOI Open-Vocabulary Evaluation), a new evaluation framework that incorporates semantic similarity between predicted and ground-truth …


Secondary English Teachers’ Perceptions Regarding The Impact, If Any, Of Shifts In The Emphasis Of History Education On Students’ Comprehension Of Literature, Bailey J. Poole May 2026

Secondary English Teachers’ Perceptions Regarding The Impact, If Any, Of Shifts In The Emphasis Of History Education On Students’ Comprehension Of Literature, Bailey J. Poole

Electronic Theses and Dissertations

This qualitative study explored secondary English teachers’ perceptions of the emphasis on history education and its perceived impact on their students’ comprehension of literature. This research used an interpretivist approach and a conceptual framework shaped by schema theory and constructivism to understand whether teachers perceived a shift in the value of history education, how they described such shifts, if any, and how they responded instructionally to those shifts, if necessary.

Data was collected through six semi-structured interviews with 11th and 12th grade English Language Arts teachers from public high schools in Mississippi, each with a minimum of ten years teaching …


Computational Investigation Of Nanoconfinement Effects On Gas Separation In Copolymer/Ionic Liquid Membranes, Azam Salmankhani May 2026

Computational Investigation Of Nanoconfinement Effects On Gas Separation In Copolymer/Ionic Liquid Membranes, Azam Salmankhani

Electronic Theses and Dissertations

The separation of carbon dioxide (CO2) from methane (CH4) is a critical process in natural gas upgrading and carbon management, yet conventional membrane materials suffer from inherent trade offs between selectivity and permeability. Ionic liquid (IL)-based membranes offer high CO2 affinity and tunable chemistry, but the mechanisms governing gas transport under nanoconfinement remain poorly understood, especially the roles of confinement geometry and interfacial ordering in controlling gas selectivity and permeability. This dissertation addresses this challenge through a multiscale computational investigation of nanoconfined ionic liquid membranes. Mesoscale simulations are used to determine how block copolymer composition and ionic liquid loading control …


Educational Placemaking: The Radical Power Of Play, Hillary René Spencer May 2026

Educational Placemaking: The Radical Power Of Play, Hillary René Spencer

Electronic Theses and Dissertations

Too often, play is dismissed as a simple childhood pastime, but what if it were understood as a radical tool for transformation? This research examines how play-based learning (PBL) interventions can serve as a framework for systemic change. Grounded in Edward Soja’s theory of spatial justice, which holds that socially valued resources and opportunities are unevenly distributed across geographic spaces (Soja, 2010), the study investigates how public spaces can serve as culturally reflective sites of learning and, when co-created with children and their communities, help address historical structural inequities. This research establishes educational placemaking as a framework for understanding play-based, …


The Impact Of Career And Technical Education Teacher Certification Preparation Programs On Student Industry-Based Certification Examinations, Kaneesha Chameka Celestin May 2026

The Impact Of Career And Technical Education Teacher Certification Preparation Programs On Student Industry-Based Certification Examinations, Kaneesha Chameka Celestin

Electronic Theses and Dissertations

Career and Technical Education (CTE) programs are designed to prepare students for high-wage, high-demand industry jobs. However, there is limited research on Career and Technical Education teacher preparation programs (traditional, alternative, and industry-based) and the impact on student outcomes on industry-based examinations, such as ACT WorkKeys. This quantitative study analyzed Career and Technical Education (CTE) teacher preparation programs (traditional, alternative, and industry-based) and 12th -grade students’ outcomes on the 2023-2024 ACT WorkKeys examination and whether relationships exist between the two. Additionally, the research examined each Career and Technical Education teacher certification preparation program individually to determine the differences among traditional, …


Disturbances In A Convergece Zone: Artisanal Fishers And The Making Of The Nearshore In Northern Coastal Peru, Leigh Shattuck Rodi May 2026

Disturbances In A Convergece Zone: Artisanal Fishers And The Making Of The Nearshore In Northern Coastal Peru, Leigh Shattuck Rodi

Electronic Theses and Dissertations

This project seeks to study how artisanal fishers in northern coastal Peru interpret and respond to environmental change provoked by three sources of harm: climate change, overfishing, and contamination. Drawing from six and a half weeks of ethnographic fieldwork among artisanal fishers in Lobitos, Peru, this paper foregrounds the concept of the nearshore assemblage to highlight the ever-shifting relations between humans and marine ecologies that constitute littoral and oceanic worlds. Artisanal fishers utilize discriminatory, non-mechanical methods to fish in a protected section of Peru’s Exclusive Economic Zone (EEZ). Fishing livelihoods in this space were previously possible because the convergence of …


Staying In Stem?: A Qualitative Exploration Of Women’S College Classroom Experiences In Stem Education, Sarah Dapaah May 2026

Staying In Stem?: A Qualitative Exploration Of Women’S College Classroom Experiences In Stem Education, Sarah Dapaah

Electronic Theses and Dissertations

Women leave STEM not because of a lack of ability, but because of the classroom and institutional conditions they encounter once they arrive. This study examines how classroom experiences shape women’s decisions to persist in or leave STEM majors at the college level. Drawing on the sociological frameworks of doing gender, gendered organizations, and intersectionality, this study explores how gender, race, and class shape women’s experiences of belonging, support, discouragement, and recognition in STEM. Using 21 semi-structured interviews and 4 classroom observations at the University of Mississippi, the study analyzes the experiences of undergraduate women who remained in STEM, women …


Connecting The Dots: Hbcus, Access To Ai Education, And The Realities Of Public-Private Collaboration, Whitney Wells May 2026

Connecting The Dots: Hbcus, Access To Ai Education, And The Realities Of Public-Private Collaboration, Whitney Wells

Electronic Theses and Dissertations

As artificial intelligence (AI) continues to reshape workforce demands and educational priorities, this partnership has emerged as a potentially effective mechanism for advancing equitable access to emerging technologies. However, limited research has explored how and why diverse organizations engage in such collaborations, particularly in regions facing persistent educational and economic disparities. This study examines the organizational motivations driving participation in the Mississippi AI Collaborative (MAIC), a multi-sector partnership involving a higher education institution, industry partners, nonprofits, and a K-12 system. While the MAIC focuses specifically on AI education and training, the purpose of this study is not to examine AI …


Exploring Integrated Arts Education For Students With Autism, Karen Denise Harrison May 2026

Exploring Integrated Arts Education For Students With Autism, Karen Denise Harrison

Electronic Theses and Dissertations

Students with autism spectrum disorder (ASD) are often misunderstood because of challenges in communication, social-emotional development, and sensory processing. Neuroscience research highlights that individuals with ASD process information and stimuli differently, particularly in areas related to sensory integration, executive functioning, and emotional regulation. Traditional educational methods often isolate these students from their neurotypical peers, reducing opportunities to engage meaningfully with standards-based curricula. Integrated arts education offers an alternative approach, aligning with neuroscience principles by engaging multiple brain regions through movement, rhythm, imagery, and creativity, allowing students with ASD to demonstrate their learning through project-based and creative experiences that meet diverse …


Kairosformer: Hybrid Transformer For Time Series Forecasting, Koichi Nishida May 2026

Kairosformer: Hybrid Transformer For Time Series Forecasting, Koichi Nishida

Electronic Theses and Dissertations

Long-term time-series forecasting is a fundamental problem in real-world applications such as financial modeling and weather forecasting. While Transformer-based architectures have shown strong performance in sequence modeling like natural language processing and computer vision, their direct application to time-series forecasting faces challenges including quadratic computational complexity and capturing inherent temporal dependencies. Recent works such as Informer and Autoformer address these limitations through sparse attention mechanisms and series decomposition, but introduce trade-offs between predictive accuracy and computational efficiency.

In this thesis, we propose Kairosformer, a Transformer-based architecture for long-horizon time-series forecasting that integrates probabilistic attention with series-wise temporal aggregation. By combining …


Adversarial Llm-Gans For Robust Synthetic Pharmaceutical Data In Self-Emulsifying Drug Delivery Systems, Samiul Islam Niloy May 2026

Adversarial Llm-Gans For Robust Synthetic Pharmaceutical Data In Self-Emulsifying Drug Delivery Systems, Samiul Islam Niloy

Electronic Theses and Dissertations

The formulation of self-emulsifying drug delivery systems (SEDDS) represents a pivotal advancement in improving the oral bio-availability of poorly water-soluble pharmaceutical compounds, yet traditional development is heavily hindered by limited experimental datasets and the complexity of predicting key quality attributes like nanoparticle size and drug release profiles. Because empirical methodologies struggle to balance formulation constraints with predictive accuracy, this research introduces a comprehensive framework that leverages state-of-the-art generative artificial intelligence to synthesize realistic, constraint-compliant SEDDS datasets. The study proposes two primary methodologies to overcome data scarcity: a novel Drug Formulation Agent (DFA) powered by Large Language Models (LLMs) and a …