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A Longitudinal Study Of Mississippi’S Achievement Scores And School Ratings Based On Principal Preparation, Brittaney Boyd Jan 2024

A Longitudinal Study Of Mississippi’S Achievement Scores And School Ratings Based On Principal Preparation, Brittaney Boyd

Electronic Theses and Dissertations

The role of the principal is complex, and there are many ways principals might potentially influence classroom instruction and student learning (Allensworth & Hart, 2018). Over the last decade, the principal’s effectiveness has been evaluated based on student achievement.

The purpose of this quantitative study, A Longitudinal Study of Mississippi’s Achievement Scores and School Ratings Based on Principal Preparation is to determine whether a significant difference exists between Mississippi’s alternate and traditional route principal preparation graduates based on academic successes for the 2017-2018, 2018-2019, 2021-2022, and 2022-2023 school terms, whether a significant difference exists among the different Institutions of Higher …


Applying Dynamics And Geophysical Methods To Hawaiian Volcanic Terrains And Lava Flows, Brody K. Conner Jan 2024

Applying Dynamics And Geophysical Methods To Hawaiian Volcanic Terrains And Lava Flows, Brody K. Conner

Electronic Theses and Dissertations

Presented here is the culmination of research spurred by a month-long field expedition to the windward side of the Big Island of Hawai’i during July and August 2023. During this expedition, two ground-penetrating radar units, a Mala GX 160 MHz antenna and a Crossover 1760 dual frequency antenna, were used to survey the basaltic, volcanic landscapes of Mauna Loa and Kīlauea. Post-eruptive digital elevation models of the Ahu’ailā’au (2018 Lower Puna) Eruption and Quantum Geographic Information Systems were used in tandem with GPR Insights software to provide a thorough picture of the surface and subsurface lava flows from Ahu’ailā’au. Using …


Standard And Non-Standard Neutrino Oscillations At The Nova Experiment, Luiz Ricardo Prais Jan 2024

Standard And Non-Standard Neutrino Oscillations At The Nova Experiment, Luiz Ricardo Prais

Electronic Theses and Dissertations

Initially believed to be massless, the discovery of neutrino oscillations proved that neutrinos have masses, a feature not anticipated by the Standard Model of Elementary Particles. Investigations of the existence of the so-called physics Beyond the Standard Model is a subject of active effort in the field of particle physics. Interactions of neutrinos with matter are well described by the Standard Model, however in the presence of new physics our knowledge and ability to measure the standard neutrino oscillation parameters may be affected. Non-Standard Interactions (NSI) may arise as a subleading effect to the neutrino oscillation framework by introducing additional …


Artificial Intelligence And Image-Based Phenotyping For Monitoring Morpho-Physiological Dynamics In Grapevines, Prakriti Sharma Jan 2024

Artificial Intelligence And Image-Based Phenotyping For Monitoring Morpho-Physiological Dynamics In Grapevines, Prakriti Sharma

Electronic Theses and Dissertations

Plant phenotypic features are essential for determining the structure, composition, and function of plants. These traits are controlled by both environmental variables and genetic makeup. Conventional manual methods of phenotyping, although time-consuming and not very accurate, have laid the foundation for more modern approaches such as high throughput phenotyping (HTP). HTP utilizes imaging, sensor networks, robotics, and data analytics to automate the process of collecting and analyzing data. This study utilizes hyperspectral and digital imaging techniques to quantify physiological, biochemical, and morphological characteristics in grapevines. Hyperspectral imaging was leveraged to collect spectral data for evaluating physiological factors, whereas digital imaging …


Removal Of Phosphorous, Copper And Zinc From Stormwater Using Powdered Activated Carbon (Pac) Based Water Treatment Residuals, Foysol Mahmud Jan 2024

Removal Of Phosphorous, Copper And Zinc From Stormwater Using Powdered Activated Carbon (Pac) Based Water Treatment Residuals, Foysol Mahmud

Electronic Theses and Dissertations

The main aim of this research was to evaluate the efficacy of Powdered Activated Carbon (PAC) based water treatment residual (WTR) in eliminating phosphorus (P), Copper (Cu), and Zinc (Zn) from stormwater. The characteristics of the PAC WTR were analyzed, and a series of batch and column tests were conducted to determine its capacity to remove P, Cu, and Zn from stormwater and synthetic solutions. The PAC WTR conformed to the Langmuir isotherm model, demonstrating P adsorption capacities of 3.51 mg/g at pH 5. Regarding Cu and Zn removal, the PAC WTR also adhered to the Langmuir isotherm model, showing …


Estimating South Dakota’S Capacity To Meet K-12 School Meal Fruit And Vegetable Requirements With State-Grown Produce, Bridgette Bienias Jan 2024

Estimating South Dakota’S Capacity To Meet K-12 School Meal Fruit And Vegetable Requirements With State-Grown Produce, Bridgette Bienias

Electronic Theses and Dissertations

Objective: Quantify South Dakota (SD)’s capacity to procure locally-sourced fruit and vegetables (FVs) for K-12 school meals.
Methods: Secondary analysis of 2017 SD agricultural census and school meal data. Yields were converted to edible cups of FVs using school meal guidelines provided by the U.S. Department of Agriculture. Student enrollment and meal redemptions were used to estimate the number of FV cups needed.
Results: Estimated SD FV production met minimum total K-12 cup requirements, except for total fruit (66%) and dark green vegetables (80%). Legumes supplied 77% of the total cups of vegetables produced in 2017, whereas dark green vegetables …


Feasibility Study Of Managing Peak Cooling Loads To Achieve Energy Cost Reduction In A Northern Climate Campus, Mark Rizkalla Jan 2024

Feasibility Study Of Managing Peak Cooling Loads To Achieve Energy Cost Reduction In A Northern Climate Campus, Mark Rizkalla

Electronic Theses and Dissertations

South Dakota State University Facilities and Services Office is facing the challenge of paying high electricity bills every year, the potential of campus growth will add more burden on the energy needed to cover this demand, especially in summer months when high cooling loads are added to the electrical loads which lead to the peak loads that costs SDSU a large amount of money. The purpose of this research is to study the feasibility of managing the peak loads to reduce energy costs by applying a suitable system that fits SDSU campus nature. The methodology used is studying the capability …


Structural Construction And Surface Modification Of Copper Current Collectors For Lithium Metal Batteries, Yaohua Liang Jan 2024

Structural Construction And Surface Modification Of Copper Current Collectors For Lithium Metal Batteries, Yaohua Liang

Electronic Theses and Dissertations

Graphene, a prevalent anode material in commercial lithium-ion batteries, has reached its theoretical capacity limit. The imperative is to develop high-capacity anode materials to meet the growing demand for energy density. Lithium metal, renowned for its exceptionally high theoretical specific capacity density (3680 mAh g-1) and low reduction potential (-3.04 V, relative to the standard hydrogen electrode), is commonly dubbed the "Holy Grail" for negative electrode materials in high-energy-density batteries. However, practical advancements in lithium metal anodes face obstacles like low Coulombic efficiency, limited cycle life, and heightened reactivity to the electrolyte and internal short circuits resulting from lithium dendrite …


Simulation Of Reacting Supersonic Flow In A Cavity Flameholder, Mohamed Benjelloun Touimi Jan 2024

Simulation Of Reacting Supersonic Flow In A Cavity Flameholder, Mohamed Benjelloun Touimi

Electronic Theses and Dissertations

Scramjet engines, or Supersonic Combustion Ramjets, are pivotal for achieving and maintaining hypersonic flight speeds. These engines leverage the high-speed airflow to compress and mix air and fuel for combustion. A significant challenge in Scramjet engine design is ensuring stable and efficient combustion within this high-speed environment. Cavity flameholders are crucial components that stabilize the combustion process by creating a subsonic region where the fuel-air mixture can ignite and sustain combustion. This research simulates this supersonic flow within the combustion chamber to accurately model and analyze the combustion dynamics. Various turbulence models, including RANS, and DES, are evaluated for their …


Abelson (Abl) Tyrosine Kinase Inhibitors Reduce Porcine Reproductive And Respiratory Syndrome Virus (Prrsv) Replication In Vitro, Jenna Parliament Jan 2024

Abelson (Abl) Tyrosine Kinase Inhibitors Reduce Porcine Reproductive And Respiratory Syndrome Virus (Prrsv) Replication In Vitro, Jenna Parliament

Electronic Theses and Dissertations

Porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped, positive-sense, single-stranded RNA virus from the Arteriviridae family. PRRSV causes respiratory illness and reproductive failure in infected pigs. Outbreaks occurring in the United States and worldwide cause significant economic losses annually. Abelson (Abl) tyrosine kinase is a non-receptor tyrosine kinase, which plays a central role in regulating many cellular processes such as actin reorganization, cell proliferation and differentiation by transducing extracellular and intracellular signals. Abl inhibitors have been shown to restrict the entry of membrane fusion of enveloped viruses, such as severe acute respiratory syndrome coronavirus, Middle Eastern respiratory syndrome …


Evaluation Of Nutrient Removal From Modified Woodchips And Organic Matter Leached From Tree Leaves After Simulated Wildfire Thermal Alteration, Zengyue Wang Jan 2024

Evaluation Of Nutrient Removal From Modified Woodchips And Organic Matter Leached From Tree Leaves After Simulated Wildfire Thermal Alteration, Zengyue Wang

Electronic Theses and Dissertations

Nonpoint source pollution (NPS) from stormwater runoff, carrying a variety of contaminants, presents substantial challenges to water treatment processes and public health. Among the primary pollutants, phosphate and nitrate significantly contribute to the degradation of water quality, resulting in issues such as eutrophication and methemoglobinemia. Tree leaves, which are a major source of dissolved organic carbon (DOC) in forested watersheds and serve as a key fuel for wildfires, further exacerbate these challenges. Post-wildfire, the altered DOC is mobilized by precipitation, leading to stormwater runoff that impacts natural water bodies and complicates treatment processes, particularly through the formation of hazardous disinfection …


Evaluating The Impact Of Perceptual Loss In Generative Adversarial Models And Diffusion Models For Document Image Enhancement, Farzaneh Karimpour Jan 2024

Evaluating The Impact Of Perceptual Loss In Generative Adversarial Models And Diffusion Models For Document Image Enhancement, Farzaneh Karimpour

Electronic Theses and Dissertations

Documents often suffer from various types of degradation which make them difficult to read and restrict OCR performance. This study investigates the effectiveness of perceptual loss in enhancing document image cleanup by comparing a GAN-based model and a diffusion model. In our experiments, we utilized the DE-GAN model as a GAN-based model and the NAF-DPM model as a diffusion model, both enhanced by incorporating perceptual loss. We then compared the results of both models and evaluated them by using the DIBCO 2013, DIBCO 2017, and H-DIBCO 2018 datasets revealed that our approach consistently outperforms existing state-of-the-art methods. Results showed that …


Reimagining Hunting Through Women's Decision Space, H. Nash Jackson Jan 2024

Reimagining Hunting Through Women's Decision Space, H. Nash Jackson

Electronic Theses and Dissertations

Approximately 14.4 million people hunt in the United States, yet only 3.1 million (22%) of these hunters are women. To enhance women’s participation, many state natural resource agencies aim to reduce barriers and create pathways for women to hunt. Previously, researchers surveyed women to understand and describe barriers to their full participation in hunting. However, this methodology often just quantifies the different barriers without describing the interconnectedness and how the complexity of barriers can impact women’s participation in hunting. This thesis instead took an inductive research approach with the goal of better understanding women’s perspectives when faced with complex barriers. …


Translocations Of North American Bison Across Large Climatic Gradients: Impacts On Thermoregulation, Body Size, And Helmintic Infection, Hayden Wolfe Jan 2024

Translocations Of North American Bison Across Large Climatic Gradients: Impacts On Thermoregulation, Body Size, And Helmintic Infection, Hayden Wolfe

Electronic Theses and Dissertations

Every year, one-eighth of all North American bison (Bison bison) are translocated, often across large climatic gradients. Over the last 16 years bison have been translocated from Wind Cave National Park in South Dakota to establish six herds across the United States central grasslands in Iowa, Missouri, Illinois, Indiana, and Kansas. Influence of climatic gradients on herd-level thermoregulation, body size, and helmintic infection were evaluated. Overall, 1174 thermal images and 1050 fecal samples were collected between 2021 and 2023. Physiological heat flux was used to measure thermoregulation, asymptotic body mass (ABM) was used for body size, and helminth genera abundance …


Comparative Analysis Of Deep Learning-Based Anomaly Detection Models For Gps Spoofing Detection, Hasan Mirzakhaninafchi Jan 2024

Comparative Analysis Of Deep Learning-Based Anomaly Detection Models For Gps Spoofing Detection, Hasan Mirzakhaninafchi

Electronic Theses and Dissertations

As autonomous vehicles (AVs) become integral to modern transportation, their susceptibility to cyber-attacks, particularly GPS spoofing, presents a serious security threat. This study addresses these challenges by applying a suite of deep learning models to enhance the detection of anomalous GPS signals. Focusing on autoencoder-based architectures, the proposed models such as long short-term memory-based variational autoencoder (LSTM-VAE), LSTM-based autoencoder (LSTM-AE), multilayer perceptron-based variational autoencoder (MLP-VAE), MLP-based Autoencoder (MLPAE), Stacked LSTM-based variational autoencoder (Stacked-LSTM-VAE), stacked LSTM-based autoencoder (Stacked-LSTM-AE), memory-augmented-LSTM-VAE (Mem-LSTM-VAE), and time-series-anomaly-detection-generative-adversarial-networks (TadGAN) were trained exclusively on authentic GPS data. This unsupervised learning approach which used for the above-mentioned models enables …


Degradation Of Total Organic Halogen In Drinking Water Distribution Systems With Iron And Iron Corrosion Products, Rachel Zook Jan 2024

Degradation Of Total Organic Halogen In Drinking Water Distribution Systems With Iron And Iron Corrosion Products, Rachel Zook

Electronic Theses and Dissertations

The presence of halogenated disinfection by products, also known as total organic halogen (TOX), found in treated water samples are toxic in nature and can negatively impact the public health. The TOX compounds may undergo reduction reactions in drinking water distribution systems (DWDS) with iron materials that include zero valent iron, and iron corrosion products of goethite and magnetite in corroded sections of pipe. The objective of this research was to investigate the degradation kinetics of total organic chlorine (TOCl), total organic bromine (TOBr), and total organic iodine (TOI) in water with iron and corrosion products. Batch experiments were completed …


Do Agricultural Commodity Price Spikes Always Stem From News?, Zhouxin Li Jan 2024

Do Agricultural Commodity Price Spikes Always Stem From News?, Zhouxin Li

Electronic Theses and Dissertations

This study delves into the occurrence and differentiation of significant price jumps in agricultural commodity markets, challenging the conventional belief that such movements are solely driven by exogenous factors. Existing literature has primarily focused on the impact of news on agricultural commodity prices, neglecting the distinction between endogenous and exogenous price spikes. I aim to identify and categorize both types of price spikes in corn, soybean, and wheat futures markets. I propose a comprehensive methodology involving the collection of agricultural news, non-parametric price jump detection, and differentiation between exogenous (newsdriven) and endogenous (non-news related) price spikes. By utilizing intraday price …


Improving Stream Connectivity In South Dakota, Colton Rainier Curtis Jan 2024

Improving Stream Connectivity In South Dakota, Colton Rainier Curtis

Electronic Theses and Dissertations

Stream connectivity is crucial for fish movement and genetic diversity in fragmented landscapes. Road-crossings often act as barriers, disrupting hydrology and isolating fish populations. The Southeast Aquatic Resources Partnership (SARP) has developed rapid road-crossing assessment protocols and tools to prioritize restoration projects. However, managers lack tools for planning, directing, and initiating roadcrossing assessments. Managers also require modeling approaches to effectively identify and monitor road-crossings across dynamic stream networks. Presented here is a case study offering a roadmap for effective implementation of collaborative road-crossing assessments and prioritization of remediation projects, alongside an exploration of predictive modeling approaches to identify problematic crossings …


2,3,4 Trihydroxybenzoic Acid, A Plant Secondary Metabolite Inhibits Cancer Cell Growth, Mina Akter Jan 2024

2,3,4 Trihydroxybenzoic Acid, A Plant Secondary Metabolite Inhibits Cancer Cell Growth, Mina Akter

Electronic Theses and Dissertations

Nature offers many sources such as fruits, beverage crops, vegetables, herbs, spices, tea, dark chocolate, and wine, that are rich in hydroxybenzoic acids (HBAs). They are a prominent phenolic acids with excellent biochemical and antioxidant properties. Due to the vast dietary health benefits of HBAs such as anti-inflammatory, anti-allergenic, immunoregulatory, antimicrobial, antithrombotic, antidiabetic, anticancer properties and cardioprotective capabilities, they are attracting the attention of physicians and researchers alike to understand their mechanisms of action. It is anticipated that the understanding of the role of HBAs for their greater use in diet/supplements is beneficial to reverse common illnesses such as inflammation, …


Access To Banking : A South Asian Perspective, Aditi Poudel Jan 2024

Access To Banking : A South Asian Perspective, Aditi Poudel

Electronic Theses and Dissertations

This study examines the driving factors behind gender disparities in access to banking services in South Asia (Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, Sri Lanka) with a focus on legal indicators (assets, marriage, mobility, parenthood, pay, pension, workplace) and gross domestic product (GDP) per capita. The choice of South Asia is not just due to the sheer number of women affected by financial exclusion but also because of its economic significance and the opportunity for substantial impact through legal and economic reforms in the world economy. Employing logistic regression models, I examine the critical legal and economic determinants influencing …


Overwhelmed And Unsupported: The Experiences Of Long-Term Care Certified Nursing Assistants With Traumatic Events, Nicole L. Carlson Jan 2024

Overwhelmed And Unsupported: The Experiences Of Long-Term Care Certified Nursing Assistants With Traumatic Events, Nicole L. Carlson

Electronic Theses and Dissertations

No abstract provided.


The Effect Of Supportive Relationships And A Sense Of Community On The Success Of First-Year College Students, Stetson K. Akers Jan 2024

The Effect Of Supportive Relationships And A Sense Of Community On The Success Of First-Year College Students, Stetson K. Akers

Electronic Theses and Dissertations

Colleges and universities across the United States actively seek to bring quality students to their institutions and retain them through their course of study while striving to support the successful completion of their degree. The problem is that students face many sources of adversity within their first year of college and leave the institution they have enrolled in before returning for their second year, including financial issues, mental health struggles, and academic success problems. The reasons students leave vary, but it remains important to help students feel connected to the community of their campus while supporting their mental health during …


Wise Blood Through The Lens Of Reader Response Theory, Hannah Rose Horton Stewart Jan 2024

Wise Blood Through The Lens Of Reader Response Theory, Hannah Rose Horton Stewart

Electronic Theses and Dissertations

Flannery O’Connor’s 1952 novel, Wise Blood, is a frequently misunderstood classic. While O’Connor is very rarely associated with reader response theory, its framework offers a way to more fully appreciate O’Connor as an author and Wise Blood as a novel while addressing aspects of critics’ confusion. The objective of this study is to consider a previously under-researched area of O’Connor scholarship while offering greater clarity to Wise Blood. By considering O’Connor’s personal nonfiction writing and the text of her first novel through the lens of reader response scholars such as Wolfgang Iser, this study offers a call towards viewing …


Evaluation Of A Novel Corn Fermented Protein Ingredient, Probiotics, And Postbiotics On Nursery Pig Growth Performance And Gut Health, Juan F. Castillo Zuniga Jan 2024

Evaluation Of A Novel Corn Fermented Protein Ingredient, Probiotics, And Postbiotics On Nursery Pig Growth Performance And Gut Health, Juan F. Castillo Zuniga

Electronic Theses and Dissertations

Weaning is a necessary step in pig production. After weaning, pigs are subjected to various nutritional, psychological, and environmental stresses. The weaning period is an important period for the intestinal development of the pig. During this time, digestion, immunity, metabolism, and various other aspects of the pig change rapidly. Therefore, providing high-quality feed ingredients is crucial to encourage the newly weaned pig to start consuming solid feed. Two independent studies were conducted to determine if the inclusion of: 1) corn fermented protein (CFP) or 2) probiotics or postbiotics impact nursery pigs' growth performance and gut health. The first experiment utilized …


The Effect Of Social Determinants Of Health On End-Stage Kidney Disease Mortality Across Diverse Adult Populations: Systematic Review And Meta-Analysis, Prince Agyapong Jan 2024

The Effect Of Social Determinants Of Health On End-Stage Kidney Disease Mortality Across Diverse Adult Populations: Systematic Review And Meta-Analysis, Prince Agyapong

Electronic Theses and Dissertations

Background: This systematic review and meta-analysis aimed to examine the influence of social determinants of health (SDOH) on End-Stage Kidney Disease (ESKD) mortality among diverse racial populations. Given the high morbidity and mortality associated with ESKD, understanding the impact of various SDOH factors across different racial groups is crucial for improving patient outcomes.
Methods: A comprehensive literature search was conducted to identify studies reporting on the relationship between SDOH and ESKD mortality using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) format. Citations were collated in EndNote 21 and screened in Covidence by two independent reviewers, with inter-rater …


The Role Of Gender And Age In Shaping Attitudes Towards Childcare And Financial Roles In American Families, Spoorthi Golla Vasantha Narender Jan 2024

The Role Of Gender And Age In Shaping Attitudes Towards Childcare And Financial Roles In American Families, Spoorthi Golla Vasantha Narender

Electronic Theses and Dissertations

This study explores public attitudes towards parental roles in childcare and financial support, employing Risman’s theory of gender as a social structure as the theoretical framework. Utilizing data from the General Social Survey (GSS) of 2022, the research examines how gender and age influence attitudes about the involvement of mothers and fathers in children’s lives. The analysis reveals significant gendered attitudes. That is, women demonstrate a greater tendency towards supporting equitable sharing of childcare duties and financial responsibilities. Conversely, with men often endorsing traditional roles for mothers as primary caregivers and men as primary financial providers. The study also identifies …


Evaluating Deterministic Approaches To Forecast Population By Educational Attainment In The United States, Wei Gu Jan 2024

Evaluating Deterministic Approaches To Forecast Population By Educational Attainment In The United States, Wei Gu

Electronic Theses and Dissertations

Forecasting population by educational attainment not only benefit government planning on allocating educational resources, labor market demand, and long-term human capital and overall well-being of society (Lutz et al. 2008), but also help predicting size and structure of future population (Lutz and KC 2011). To seek effective method to produce precise results with limited resources, this dissertation compared the Cohort Component Method (CCM) and Hamilton Perry (HP) method to forecast population that are 25 years and older with Associate’s degree and above, and evaluated how factors may impact the accuracy, and how factors interact with each other to influence the …


Field Scale Evaluation Of A Flow-Through Filtration System With Mixed Media To Remove E. Coli From Stormwater, Ankur Debnath Jan 2024

Field Scale Evaluation Of A Flow-Through Filtration System With Mixed Media To Remove E. Coli From Stormwater, Ankur Debnath

Electronic Theses and Dissertations

The main goal of this research was to establish a field-scale stormwater filtration system which is flow-through and cost-effective in terms of construction and maintenance. The filter is constructed in a downstream drainage of a retention pond where the stormwater goes through the porous space of media so that it maintains low retention time with minimum disturbance in flow. The filter consists of two 20ft long sections with concrete channel and ripraps on the inlet & outlet side. 30% Steel chips and 70% steel slags in the size range of 6.00-12.5 mm have been used as media which has been …


Identification And Characterization Of Three Novel Rumen Bacterial Species In Sheep Fed A Concentrate Diet, Reid Frederick Anema Jan 2024

Identification And Characterization Of Three Novel Rumen Bacterial Species In Sheep Fed A Concentrate Diet, Reid Frederick Anema

Electronic Theses and Dissertations

Sheep production in the United States is a popular venture for both small farmers and large enterprise owners, as there is a market for end products such as wool and meat. One major factor of raising sheep is nutrition as an adequate diet will allow an animal to reach its full genetic potential for growth. With that in mind, the composition of the diet must be formulated to benefit the animal. Ruminants have the ability to use a variety of plants that are often inedible for humans to create products that humans can consume. These varying feedstuffs, whether they include …


Breast Tissue As A Local Drug Reservoir For Anticancer Therapy In Breast Cancer, Saniia Shchinar Jan 2024

Breast Tissue As A Local Drug Reservoir For Anticancer Therapy In Breast Cancer, Saniia Shchinar

Electronic Theses and Dissertations

Breast cancer, particularly the estrogen receptor-positive (ER+) subtype, remains a formidable challenge in oncology. Traditional oral therapies for ER-positive breast cancer, such as selective estrogen receptor modulators (SERMs) like Tamoxifen (TAM) and Toremifene (TOR), often encounter issues related to limited bioavailability, metabolic complications, and significant systemic side effects. These side effects include the risk of blood clots, hot flashes, vaginal dryness, menstrual cycle disruptions, and uterus cancer, which can hinder long-term adherence to preventive therapy. The exploration of local drug delivery into breast tissue presents a promising alternative to tackle these challenges. In this study, we explored the feasibility of …