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Articles 1021 - 1050 of 21005
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Buried Pipeline Performance Under Surface Loading Using Finite Eelement Analyses And Innovative Soil Box Testing Methodologies., Adam Gabreil Cantrell
Buried Pipeline Performance Under Surface Loading Using Finite Eelement Analyses And Innovative Soil Box Testing Methodologies., Adam Gabreil Cantrell
Electronic Theses and Dissertations
Buried pipelines are used extensively in the utility industry to deliver natural gas to customers. Reasonable estimates indicated that there are approximately 26,000,000 miles of pipeline, of various diameters throughout the United States (PHMSA, 2018). For protection, and to relieve urban congestion, these pipelines are nearly always buried under ground. After the pipes are installed, however, there is little opportunity for inspection, or for supplemental protection, when needed. Thus, to reduce the likelihood of rupturing a natural gas pipeline, design guidelines that ensure consistent, minimum protection of these utilities, have been developed and implemented. Pipeline design and installation regulations for …
Constitutive Chefs: The Ethos And Constitutive Rhetoric Of Anthony Bourdain, Sean Sherman, And Mashama Bailey., Michael Jared Benjamin
Constitutive Chefs: The Ethos And Constitutive Rhetoric Of Anthony Bourdain, Sean Sherman, And Mashama Bailey., Michael Jared Benjamin
Electronic Theses and Dissertations
This dissertation project explores the motivation of chefs to become Public Chef Intellectuals and how they cultivate and engage with an audience that will never taste their food. Using a case study approach, this dissertation analyzes the intellectual missions of Anthony Bourdain, Sean Sherman, and Mahsama Bailey as told through their television shows, memoirs, cookbooks, and restaurant menus. I argue that for each chef, their cultural identity is inextricably tied to their ultimate purpose – the use of food as a Trojan horse to promote their vision for a collective American culture. This project underscores that this process happens dialogically …
Proteolytic Manipulation Of Neutrophil Responses And The Efferocytic Synapse By Porphyromonas Gingivalis., Kelley N. Cooper
Proteolytic Manipulation Of Neutrophil Responses And The Efferocytic Synapse By Porphyromonas Gingivalis., Kelley N. Cooper
Electronic Theses and Dissertations
Porphyromonas gingivalis (Pg) is etiologically associated with chronic periodontitis, a highly prevalent chronic inflammatory disease characterized by the destruction of hard and soft tissues of the periodontium. Pg is adapted to live in the human oral subgingival niche, a hostile environment dominated by excessive numbers of activated neutrophils and antimicrobial mediators. Its survival is contingent upon prompt and effective inactivation of neutrophil effector functions. In this dissertation, I uncover a novel pathogenic mechanism employed by Pg that disarms the antimicrobial capacity of live neutrophils and simultaneously sequesters them within macrophages. Mechanistically, RgpB, a cysteine protease produced by Pg …
Defining The Peripheral Plasticity Of Nociceptive Afferents Following Spinal Cord Injury And Physical Therapy Intervention., Morgan Julianna Forston
Defining The Peripheral Plasticity Of Nociceptive Afferents Following Spinal Cord Injury And Physical Therapy Intervention., Morgan Julianna Forston
Electronic Theses and Dissertations
The focus of this dissertation is to explore the peripheral plasticity of nociceptive afferents following spinal cord injury (SCI) and whether it is exacerbated or induced when physical therapy-based muscle stretching, a therapy we have shown to be detrimental to locomotor recovery in rodents, is implemented post-SCI. Chapter I provides a brief introduction on sensory afferents with particular emphasis on nociceptive afferents and their multifaceted role within the peripheral and central nervous systems. Chapter II describes SCI epidemiology and common sensory related complications that occur in patients as well and pharmaco- and physical therapies that are employed post-SCI. Chapter III …
Liquid Chromatography-Mass Spectrometry Based Metabolomics, Lipidomics And Epitranscriptomics., Raobo Xu
Liquid Chromatography-Mass Spectrometry Based Metabolomics, Lipidomics And Epitranscriptomics., Raobo Xu
Electronic Theses and Dissertations
Metabolomics and lipidomics are the comprehensive studies of metabolites and lipids in cells, biological fluids, tissues, or organisms. These distinct chemical fingerprints are left behind by cellular processes. Epitranscriptomics is the field that focuses on examining chemical modifications on RNA molecules at the transcriptome level. Liquid chromatography-mass spectrometry (LC-MS) has been widely used in those omics studies. In this dissertation, I developed and applied both untargeted and targeted approaches using LC-MS based various analytical platforms to conduct omics studies. Firstly, I investigated caffeine metabolites in human urine and discovered three potential functional biomarkers to differentiate the stages of alcohol-associated liver …
A Quantitative Evaluation Of An Innovative Family Treatment Court Program For Families With Co-Occurring Child Maltreatment And Substance Use., Ashley Rose Logsdon
A Quantitative Evaluation Of An Innovative Family Treatment Court Program For Families With Co-Occurring Child Maltreatment And Substance Use., Ashley Rose Logsdon
Electronic Theses and Dissertations
Substance use is linked to out-of-home care in over 40% of child welfare cases. This dissertation evaluated the experience of families with co-occurring child maltreatment and substance use in Family Recovery Court (FRC), an innovative family treatment court involving the judicial system, child welfare system, and behavioral health. Study One used a quasi-experimental propensity score match design, using administrative data and the North Carolina Family Assessment Scale for 68 families. The FRC group experienced better safety (substantiated repeat maltreatment), permanency (reunification), and well-being outcomes. The percentage of the FRC group who achieved reunification (81.2%) was significantly higher than that of …
A Little Bit Of Everything: Persistence Though The Pre-Medical Pipeline For First And Continuing Generation Students., Tana R. Didelot
A Little Bit Of Everything: Persistence Though The Pre-Medical Pipeline For First And Continuing Generation Students., Tana R. Didelot
Electronic Theses and Dissertations
This qualitative research study examines pre-medical college student persistence in their pathway to medical education. Through the framework of Terenzini and Reason’s College Student Persistence Model (2005), this work sought to understand the pre-college experiences, campus support factors, and external environments that help pre-medical college students to continue toward their goal of medical school entry. This study included pre-medical undergraduate students in the campus context of one public institution in the Southern Unites States. Pre-medical upperclassmen students were interviewed using a semi-structured protocol developed with the persistence framework. The analysis was conducted to obtain a more nuanced understanding of the …
Understanding How Social Media Influences Student Engagement Within The Classroom: Middle Grades Students' Perspectives., Anthony Dawyne Myrks-Brewer
Understanding How Social Media Influences Student Engagement Within The Classroom: Middle Grades Students' Perspectives., Anthony Dawyne Myrks-Brewer
Electronic Theses and Dissertations
This dissertation investigated the concept of student engagement and participation through the lens of middle school students. Studies and research show that overall student engagement amongst middle school-aged students is the most unengaged period throughout students' K-12 educational journey. Today's students live in a completely different generation from their guardians and parents due to the technology component, including smartphones making the element of social media more accessible. Social media is a platform that helps people communicate through various applications, and middle school students engage and participate in various social media applications daily. Student engagement is a critical component within education …
Patient, Provider, And Health System Characteristics Leading To The Delivery Of Low Value Health Care Services And Outcomes Of An Intervention For Mitigating Low Value Care., Philip Ray Rohrer
Electronic Theses and Dissertations
The United States spends more on health care than any other country, and Medicare accounted for nearly one-quarter of total personal health care spending in 2019. Waste within the health care system in the United States is estimated to represent approximately 25% of total U.S. health care expenditures. Low value care includes health care services that provide little or no benefit to patients, have potential to cause harm, incur unnecessary costs to patients, or waste limited healthcare resources. Low value care is estimated to represent roughly 10% of total health care waste, or between $75.7 billion and $101.2 billion dollars …
How White Supremacy Travels Through Time: Anti-Literacy Laws, Dei Bans, And The Issue Of Black Self-Determination In Public Health., Nicole V. Ford
How White Supremacy Travels Through Time: Anti-Literacy Laws, Dei Bans, And The Issue Of Black Self-Determination In Public Health., Nicole V. Ford
Electronic Theses and Dissertations
This dissertation used a qualitative policy content analysis (PCA) of historical anti-literacy laws and modern DEI bans to answer two research questions: What is the connection between anti-literacy laws and DEI bans? How do anti-literacy laws and DEI bans create an environment that maintains white supremacy? A PCA exercise informed the analysis of historical anti-literacy laws in South Carolina (1834), Georgia (1829), North Carolina (1830), Louisiana (1830), Virginia (1831), and Alabama (1833) and modern DEI bans in Texas (2023), Alabama (2024), and Florida (2023) to find the connection between the laws. Findings from this dissertation illustrate how white supremacy operates …
Ai-Driven Approach For Diagnosis Of Renal Transplant Rejection Based On Biomarkers Identification And Integration., Israa Sharaby
Ai-Driven Approach For Diagnosis Of Renal Transplant Rejection Based On Biomarkers Identification And Integration., Israa Sharaby
Electronic Theses and Dissertations
They kidney is a vital organ for which humans are fortunate to find a spare through transplantation to sustain critical body functions, offering a hope to those struggling with renal failure. Kidney transplant procedure is the optimal treatment for people who suffer from end-stage renal failure. However, there are posed challenges due to the risk of immune rejection and the limited availability of donors. Early detection of renal rejection can provide timely intervention and accurate diagnosis that are critical to improve the transplant outcomes. This study explores the innovative approaches for addressing the current challenges through biomarkers identification, imaging techniques, …
Understanding Carceral Pathways And Outcomes Of Marginalized Adults Who Use Drugs., Carmen Renee Mitchell
Understanding Carceral Pathways And Outcomes Of Marginalized Adults Who Use Drugs., Carmen Renee Mitchell
Electronic Theses and Dissertations
This dissertation is an examination of outcomes among substance users at various stages of the incarceration process divided among five chapters. Chapter One provides an overview of substance use disorder (SUD), incarceration, and wider justice system-involvement, and explores how the political economy of health theoretical framework can be applied to examine how the criminal justice system creates and perpetuates inequality among marginalized people who use substances. Chapter Two examines post-release health outcomes among the population of incarcerated people who use substances using a scoping review and finds that people in reentry with SUD have poorer overall outcomes that without transitional …
Co-Emulation Of Robotics And Software-Defined Radio Based 5g Wireless Communications., Bhaskara Venkata Raju Garuda
Co-Emulation Of Robotics And Software-Defined Radio Based 5g Wireless Communications., Bhaskara Venkata Raju Garuda
Electronic Theses and Dissertations
The convergence of robotics and 5G wireless communication technologies has opened new avenues for real-time, dynamic robotic applications. This dissertation introduces a novel framework that integrates the Robot Operating System (ROS), Software-Defined Radios (SDRs), and 5G wireless networks to achieve seamless coemulation of robotic systems. The research emphasizes the unique features of 5G, such as ultra-low latency and high throughput, which enable critical applications like remote surgery, industrial automation, and autonomous vehicles. The methodology combines ROS for robotic control, SDRs for programmable communication channels, and 5G testbeds for high-speed, reliable data transmission. The experimental evaluation focuses on both position-based and …
Differential Responses Of Human Neutrophils To Legionella Species., Hannah E. Hanford
Differential Responses Of Human Neutrophils To Legionella Species., Hannah E. Hanford
Electronic Theses and Dissertations
Legionella species are Gram-negative facultative intracellular bacterial pathogens commonly found in freshwater or soil environments where they survive and replicate within their natural protozoan hosts. Humans serve as an accidental host for Legionella species after inhalation of contaminated aerosolized water droplets or soil particles enabling the bacteria to enter the lungs, infect alveolar macrophages, and result in severe pneumonia. Evasion of degradation and proliferation within alveolar macrophages by Legionella species and manifestation of “Legionnaires’ disease” is dependent on the Dot/Icm type IV secretion system (T4SS). The T4SS apparatus is a needle-like channel for translocation of over ~350 effector proteins, depending …
The Integration Of Environmental Concerns And Philosophy Into Business Strategies, Johann Thorne
The Integration Of Environmental Concerns And Philosophy Into Business Strategies, Johann Thorne
Electronic Theses and Dissertations
My thesis focuses on how a business can better integrate environmental philosophies and principles into their business model without detracting from the business's primary objectives, specifically that of generating profit. However, this thesis also seeks to extend the business's objectives to include the environment using these environmental philosophies, arguing that the business should have some obligation to the environment in terms of morality, as well as social obligations. This is an evolution of some common ethical theories used within the business world, but I argue they do not suffice to protect the environment. Instead, I develop an ethical pluralist framework …
Teachers’ Perception Of School Counselors’ Effectiveness When Supporting Middle-Level African American Males, Vanessa Dease
Teachers’ Perception Of School Counselors’ Effectiveness When Supporting Middle-Level African American Males, Vanessa Dease
Electronic Theses and Dissertations
Six teachers representing three sites in a single school district shared their perceptions through interviews regarding school counselors' effectiveness when supporting African American middle-level males academically, socially, and emotionally. A reflexive thematic analysis guided this study with the help of the sociocultural and expectancy theories. As participants shared their perceptions through interviews, they answered the three research questions that guided the research. The research questions are: (a) What are teachers' perceptions of the effectiveness of school counselors in addressing the unique social and emotional needs of African American male students? (b) What do educators expect of school counselors regarding supporting …
Before Ministry, Education Is Important (Bmei): A Comprehensive Enquiry About The Impact Of Education On Ministry, Mcclintock Acsmhour
Before Ministry, Education Is Important (Bmei): A Comprehensive Enquiry About The Impact Of Education On Ministry, Mcclintock Acsmhour
Electronic Theses and Dissertations
Ministry has a variety of fields ranging from churches, social nonprofit organizations, and government ministries in agriculture, health, education, lands, and many more. While this study did not focus on other ministries apart from Christian non profit ministries like church, to some extent, all leaders in these ministries avow that one requires some level of education to be in leading positions in these ministries. In other words, the qualified individual must have been trained in a particular field within the ministry of interest. This indicates the importance of education in ministry. Therefore, this study was conducted to uncover the impact …
Heat Acclimated Algae Improves Heat Tolerance And Longevity In Daphnia, Ashit Dutta
Heat Acclimated Algae Improves Heat Tolerance And Longevity In Daphnia, Ashit Dutta
Electronic Theses and Dissertations
Xenohormesis suggests that consuming stressed food provides physiological adaptation to the consumer for similar stresses. To evaluate this, Daphnia magna was provided with heat-stressed Nannochloropsis limnetica grown at 25℃ whereas the control group was provided Nannochloropsis limnetica grown at 12℃. In the heat tolerance experiment, Daphnia kept at 28℃ and 20℃ while consuming 25℃ algae had significantly higher heat tolerance compared to the control. Additionally, in stressed conditions, Daphnia consuming 25℃-grown food had significantly higher lifespan compared to the control. Next, Daphnia consuming 25℃-grown algae had significantly higher levels of antioxidants which could explain the lifespan extension. Finally, in fatty …
Early Career Teachers' Perceptions And Preparedness For Culturally Responsive Teaching When Teaching Black Youths With Behavior Challenges., Erica Brooks
Electronic Theses and Dissertations
In my study, I explore the perceptions and preparedness of early career teachers in the context of culturally responsive teaching (CRT) when instructing Black youth with behavior challenges. Early career teachers play a vital role in shaping the educational experiences of their students. Their beliefs and readiness to employ CRT practices are critical factors in addressing the unique needs of Black youth, particularly those facing behavioral difficulties. I investigated the perceptions of early career teachers regarding the importance of CRT and its effect on the learning environment. I examined how these teachers perceive the value of cultural responsiveness in managing …
Victims Unknown: An Evaluation Of The Way Louisville, Kentucky Communicated About Aids At The End Of The 20th Century, Alexander M. Vernon
Victims Unknown: An Evaluation Of The Way Louisville, Kentucky Communicated About Aids At The End Of The 20th Century, Alexander M. Vernon
Electronic Theses and Dissertations
This is thesis examines the way that printed news sources reported on AIDS during the height of the epidemic in Louisville, Kentucky. It compares between mainstream and grass-roots sources to work to identify shortcomings in reporting, and how reporting on a public health crisis can be improved upon in the future. It uses an intersectional framework to deconstruct why certain news sources reported on specific demographics of the population, across racialized and gendered lines. Chapter One analyzes the epidemic and then contextualizes the language that was used. Chapter Two focuses on mainstream local newspapers, while also defining demographics of AIDS …
Access To Health Care And Glycemic Control: The National Health And Nutrition Examinations Survey (Nhanes) 2005-2018., Mohamed M. Ali
Access To Health Care And Glycemic Control: The National Health And Nutrition Examinations Survey (Nhanes) 2005-2018., Mohamed M. Ali
Electronic Theses and Dissertations
Background and Purpose: Diabetes mellitus is a chronic metabolic condition associated with numerous medical and financial sequences. In 2018, 34.1 million adults aged 18 years or older had diabetes in the U.S. Access to Care for diabetic Americans remains a public healthcare concern. This study aims to examine the relationship between access to healthcare and selected diabetes indicators. Methods: A quantitative, repeated cross-sectional study uses four of the National Health and Nutrition Examinations Survey's (NHANES) access measures (insurance, the number of times of annual healthcare visits, routine place for healthcare, and type of place) and four diabetes indicators (Hemoglobin A1C …
Understanding Defect Dynamics In Black Phosphorene Under Noble Gas Ion Irradiation., Saransh Gupta
Understanding Defect Dynamics In Black Phosphorene Under Noble Gas Ion Irradiation., Saransh Gupta
Electronic Theses and Dissertations
Controlled introduction of defects in phosphorene using high-energy ion beams offers a promising route to design novel high-performance materials for energy technologies. However, this potential remains underexplored due to a lack of fundamental understanding of the atomic-scale mechanisms governing the production, accumulation, and temporal evolution of defects during ion irradiation. Here, we employ a combination of classical and ab initio molecular dynamics simulations to elucidate the effects of ion energy, angle of incidence, noble gas ion size/mass, and fluence on (a) defect generation (i.e., point defects, topological imperfections, voids), (b) atomic-scale mechanisms of defect formation and re-arrangement, and (c) defect …
Impact Of Human Immunoglobulin Genetic Variants On The Expressed Antibody Repertoire., Eric Engelbrecht
Impact Of Human Immunoglobulin Genetic Variants On The Expressed Antibody Repertoire., Eric Engelbrecht
Electronic Theses and Dissertations
B cells produce immunoglobulins (IGs; antibodies), which are critical protein components of the immune system. Human IGs are composed of two pairs of identical ‘heavy’ chains and ‘light’ kappa or lambda chains, encoded by genes located at three loci in the genome: the IG heavy chain locus (IGH, chromosome 14), and the IG lambda (IGL, chromosome 22) and kappa (IGK, chromosome 2) loci. Each locus spans ~920-100 kilobase pairs (Kbp) of DNA and harbors families of gene segments that are somatically rearranged during B cell development. The IG loci collectively harbor >180 functional genes, many of which are part of …
Toward An Urban Food Commons: Participatory Action Research On Food Apartheid And Community-Based Agrifood System Governance In Louisville, Ky., Mary Abigail Rudolph
Toward An Urban Food Commons: Participatory Action Research On Food Apartheid And Community-Based Agrifood System Governance In Louisville, Ky., Mary Abigail Rudolph
Electronic Theses and Dissertations
This dissertation investigates the structural inequities fueling food apartheid in Louisville, Kentucky’s agrifood system and explores community-based governance as a path toward food justice. Through a participatory action research (PAR) framework, this study combines participatory geographic information systems (PGIS), focus groups, and autoethnography to engage directly with affected community members and collaborate with the Food in Neighborhoods (FIN) coalition. By prioritizing the voices of those most impacted by food insecurity, this research offers contributions to the fields of food justice, participatory governance, and urban food commons. The study situates Louisville’s food access issues within the broader neoliberal global agrifood system, …
Sensitive Grip Mounting Surfaces For Physical Human-Robot Interaction., Branden Shay
Sensitive Grip Mounting Surfaces For Physical Human-Robot Interaction., Branden Shay
Electronic Theses and Dissertations
As the development of robotics becomes ever increasingly present in our society, the need for studying how humans and robots interact with each other becomes more of a necessity to be properly integrated in the changing world around us. In this thesis, we undertake the study and development of how to create a tactile human-robot operator interface to guide a robot perform a physical task. The implementation of tactile interfaces such as SkinCell sensor arrays emulating skin, and of a robotic handlebar fitted with tactile sensors are critical examples of the challenges that come with mounting and packaging such sensors …
Investigating The Contribution Of First-Order Streams To Floods In Downstream Water Bodies On The Central Appalachian Plateau., Luke Ott
Electronic Theses and Dissertations
Flash floods are the costliest natural disaster in Appalachia. The goal of this study is to better understand flood response in headwater streams and the role of these systems in the generation of downstream floods. We applied a process-based hydrologic model using data from the Robinson Forest environmental monitoring network to estimate the contribution of headwaters to downstream floods. We then used the model to understand the effects of landscape disturbance in headwaters on downstream floods. Finally, we developed empirical hydrologic models to identify useful data for predicting downstream peak flood discharge. Results indicate that headwaters in our study catchment …
The Ethics Of Vulnerability In Health Care, Hannah Dieterle
The Ethics Of Vulnerability In Health Care, Hannah Dieterle
Electronic Theses and Dissertations
This dissertation seeks to address vulnerability within clinical healthcare settings. Currently, clinical vulnerability is underrecognized and insufficiently researched which leads to the perpetuation of negative health outcomes for vulnerable populations. Specifically, there is a lack of a consistent and universal definition of vulnerability which has built a shaky foundation on which to discuss vulnerability. This dissertation begins to address these issues and increase awareness on clinical vulnerability due to some populations experiencing the devastating effects of vulnerability at a higher and disproportionate rate when compared to other populations. There is a clear need for increased attention from ethicists and medical …
K-3 Teachers’ Self-Efficacy For Teaching Reading And Its Relationship On K-3 Students Reading Achievement: A Mixed-Methods Study, Adrienne Dowden
K-3 Teachers’ Self-Efficacy For Teaching Reading And Its Relationship On K-3 Students Reading Achievement: A Mixed-Methods Study, Adrienne Dowden
Electronic Theses and Dissertations
Educators persistently grapple with heightened levels of accountability concerning their professional job performance, concomitant with the imperative to maintain commensurate standards in facilitating student achievement. Such circumstances engender heightened personal strain, potentially precipitating diminished self-esteem and consequently impeding the delivery of effective educational services to students, thereby compromising overall professional performance. Bandura (1997) delineated self-efficacy as the cognitive appraisal of one's capacity to orchestrate and execute specific tasks effectively. Moreover, he posited that individuals' anticipated outcomes are significantly influenced by their assessments of their competence to execute tasks in various contexts. Analogously, teachers' perceptions and attitudes regarding their students' overall …
Detecting Anomalies In Dynamic Attributed Graphs: An Unsupervised Learning Approach, Austin Hamilton
Detecting Anomalies In Dynamic Attributed Graphs: An Unsupervised Learning Approach, Austin Hamilton
Electronic Theses and Dissertations
Dynamic attributed graphs, which evolve over time and hold node-specific attributes, are essential in fields like social network analysis, where anomalous node detection is a growing area. Vehicular social networks (VSNs), a subset of these graphs, are ad hoc networks in which vehicles exchange data with one another and with infrastructure. In this dynamic context, identifying anomalous nodes is challenging but crucial for maintaining trust within the network. This work presents an unsupervised deep learning approach for anomalous node detection in VSNs. This model achieved an accuracy of 71% while detecting synthetic anomalies in a simulated network based on real-world …
An Exploration Of K-3 Teachers’ Beliefs, Attitudes, And Instructional Technology Use Pre-, During, And Post-Covid-19, Patience Mensah-Bonsu Aggrey
An Exploration Of K-3 Teachers’ Beliefs, Attitudes, And Instructional Technology Use Pre-, During, And Post-Covid-19, Patience Mensah-Bonsu Aggrey
Electronic Theses and Dissertations
This qualitative multiple case study explores kindergarten to third-grade teachers use of instructional technology across three different periods: pre-COVID-19, during COVID-19, and post-COVID-19. This research investigates teachers’ attitudes, the use of technological tools by teachers, and the internal (second order) and external (first order) barriers that informed their use of instructional technology before and during the COVID-19 pandemic and continue to influence their use in the post-pandemic phase. Data were collected through questionnaires, interviews, and checklists from eight kindergarten third-grade teachers using a qualitative multiple case study approach. The findings suggest that there was a shift in teachers’ instructional technology …