Digital Commons Network^™

Exploring The Role Of Clinical And Social Factors In Predicting All-Cause Mortality In End-Stage Kidney Disease Patients: A Machine Learning Framework, Addy Smith

Electronic Theses and Dissertations

No abstract provided.

Molecular Dynamics Simulations Of Key Parameters On Thermal Properties Of Carbon Nanotube Modified Epoxy Composites, Lida Najmi

Electronic Theses and Dissertations

The application of carbon nanotube (CNT)-reinforced epoxy matrix composites (CRECs) has attracted extensive attention in various industrial sectors due to the significant improvement of material properties imparted by CNTs. The thermal behavior of these nanocomposites is governed by complex heat transfer mechanisms operating at different scales, resulting in a complex relationship between the effective thermal response and the microstructural characteristics of the composite. In this study, molecular dynamics (MD) simulations were used to investigate the thermal conductivity of CRECs, focusing on the effects of key parameters such as the length and volume fraction of CNTs, the degree of cross-linking within …

Exploring The Perceptions Of School Leaders And Teachers Towards The Role And Value Of School Librarians, Amanda Galliton

Electronic Theses and Dissertations

This study explored the perceptions of school leaders and teachers toward the role and value of school librarians in a North Central Texas Education Service Center area. The study investigated how superintendents, principals, and teachers view the contributions of certified school librarians to student achievement and school culture, particularly in light of budget cuts and the elimination of librarian positions. Using a mixed-methods approach, this research gathered information from superintendents, principals, and teachers, using quantitative and qualitative data and then quantitizing that data. The results reveal a significant variance in perceptions among superintendents, principals, and teachers, as well as a …

Strategies For Success: Developing The Hero Within To Increase Persistence Of Community College Students Returning From Academic Dismissal, Angela Cavazos

Electronic Theses and Dissertations

Students are enrolling in college at a higher rate than ever before, yet retention rates continue to be problematic for higher education institutions across the United States. Many students fail to persist beyond their first year and are often forced out due to academic difficulties. Students who return from academic dismissal are likely to be dismissed again. This quasi-experimental quantitative action research study aimed to evaluate the impact that a student success intervention course designed through an asset-based positive self-leadership framework and focused on the development of psychological capital constructs of hope, efficacy, resilience, and self-efficacy (HERO) had on the …

The Lived Experiences Of African American Women In Predominantly White Higher Education Institutions In Texas And Their Journey To Advancement To Tenure, Wanda Yvonne Carter-Dyer

Electronic Theses and Dissertations

Abstract

African American women are underrepresented in predominantly White higher education institutions in Texas. Inconsistent treatment and policies have contributed to the disparate numbers of African American women in predominately White institutions. African American women are subjected to discrimination based on race, sex, and color. The problem investigated in this study was the barriers to African American tenure-seeking women in predominately White institutions. Barriers discussed in those interviews were discrimination, equity, inclusion, lack of support systems, organizational culture and relationships, and mentors. Six African American women in PWIs in Texas were interviewed to give a voice to the barriers experienced …

“But The Trauma Did Not Fade Away” Childhood Sexual Abuse, Adolescent Pregnancy, And Rurality, Cynthia H. Mcniss

Electronic Theses and Dissertations

Childhood sexual abuse (CSA) and adolescent pregnancy are critical public health issues that intersect in complex ways, particularly in rural areas. Adolescents who have experienced CSA are at a significantly higher risk of becoming pregnant before the age of 19 compared to their peers without such a history (Madigan et al., 2014). Rurality is also associated with elevated rates of adolescent pregnancy due to various socio-economic and healthcare access challenges ("Rural Health Information Hub," 2024). This study employed a grounded theory approach to develop a comprehensive understanding of the social and psychosocial processes influencing the choices, actions, and decisions of …

Gatekeeper, Keep Thyself: How Impairment Impacts The Integration Of Counselor Wellness Competencies, Curtis Lee Taylor

Electronic Theses and Dissertations

This quantitative study examined counselor educators’ beliefs regarding the importance of Counselor Wellness Competencies (CWCs) and how effectively they teach them to their counselors-in-training (CIT). This study focused on significant relationships between the importance and effective teaching, self-care, and burnout. Counselor educators who place higher importance on the CWCs reported having higher self-efficacy in teaching them. The findings suggest that counselor educators with more self-care behaviors experienced less burnout and were better able to show congruence between the importance and effective teaching of the CWCs. The conclusion of this report explores limitations and directions for future research.

Factors Affecting Involvement Of Parents Of Students With Learning Disabilities In Saudi Elementary Schools, Mohammed Alyahya

Electronic Theses and Dissertations

The research explores the factors that influence parental involvement in school children with learning disabilities in Riyadh, Saudi Arabia. Understanding these factors is crucial, as parental involvement is widely recognized as essential for the academic success of children, particularly those with learning disabilities. This study used a quantitative approach to collect data from parents of students with learning disabilities, including parents' age, gender, income, employment status, and parental beliefs (responsibilities and capabilities). The findings reveal that parental beliefs regarding their responsibilities towards their child's education are the only significant predictor of parental involvement. In contrast, other variables, including age, gender, …

Interactions Of The Sars-Cov-2 Viral Genome 3’-Untranslated Region With Viral And Host Rnas, Caleb Frye, Mihaela Rita Mihailescu

Electronic Theses and Dissertations

This dissertation focuses on the characterization of RNA-RNA interactions within the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and with host microRNAs. As the causative agent of coronavirus disease 2019 (COVID-19), SARS-CoV-2 has evolved rapidly since its appearance. This has warranted prompt characterization of the virus particularly of its single stranded RNA (ssRNA) genome. By using a combination of bioinformatics, biophysics, and/or biological assays, we analyzed the SARS-CoV-2 viral genomic RNA and uncovered interactions of genomic RNA with host RNAs, highlighting an underutilized method of targeting RNA viruses. We showed here that the conserved elements in the viral genomic …

Evaluating The Implementation Of Community Schools’ Strategies To Address Post-Pandemic Student Mental Health, Dawn Gordon

Electronic Theses and Dissertations

This research explores the systemic and structural barriers affecting the effectiveness of community schools, particularly in providing mental health services and support, with a specific focus on how principals have responded to these needs in the post-COVID-19 era. Employing qualitative methods, including focus groups with principals from schools implementing the community schools’ model, the study identifies three major themes: difficulties with lead agency collaboration and coordination with host schools, systemic and structural barriers to effective functioning, and holistic approaches to enhancing student support and well-being with mental health.

Difficulties with lead agency collaboration and coordination reveal how inadequate communication and …

The Ethical Contributions Of Nudges To Healthcare, Ian Doherty

Electronic Theses and Dissertations

“The Ethical Contributions of Nudges to Healthcare” examines the ethical use, implications, and rationale for using nudges in healthcare. The use of nudges in healthcare are being empirically examined. This leaves much to be examined from the ethical perspective. To examine the ethical perspective, the dissertation lays out how nudges interact with and enhance the biomedical principles of autonomy and beneficence. The dissertation then turns to clinical ethics. Nudges, more specifically the framing effect, are paired with trust in the patient-physician relationship to discern how best to aid a patient in his or her medical decision-making. The dissertation then investigates …

How Do Expert Forensic Evaluators Do It? A Qualitative Study Exploring Forensic Evaluators’ Lived Experiences Conducting Psychosexual Evaluations Of Sex Offenders With Suspected Autism, Jessica K. Gazzola

Electronic Theses and Dissertations

This qualitative inquiry utilized semi-structured interviews with eight expert forensic evaluators to explore their lived experiences engaging in psychosexual evaluations of sex offenders with a suspected diagnosis of autism. The purpose of this study was to identify current best practices, principles, and challenges faced by forensic evaluators when assessing sex offenders with a suspected diagnosis of autism. The results provide a variety of autism-specific screening tools and assessments used by forensic evaluators in their psychosexual evaluation process. Four emergent themes were developed using a descriptive phenomenological approach and social constructivist framework. These themes encompass forensic evaluators’ role in conducting psychosexual …

College Instructors’ Experiences Of Online English As Second Language (Esl) Teaching And Learning Environments, Jianan Zhou

Electronic Theses and Dissertations

This study investigates college ESL instructors' experiences in teaching online ESL courses. It explores the differences in teaching focus and online modes for teaching speaking, listening, reading, and writing courses. It also investigates how ESL instructors' perceived level of technology competence varies across different online teaching modes and examines how teaching and learner engagement strategies differ depending on the instructional modality. Key findings include the observation that both BICS and CALP were prevalent in online reading courses. Although no significant difference in technology competence between asynchronous and synchronous modes was found, it was shown that instructors used more synchronous modes …

It's Funny When You Think About It: Formal Complexity And Emotional Engagement In Twentieth Century American Humor, Noel Stanger

Electronic Theses and Dissertations

It is generally accepted by scholars of humor that humor requires an observer to take on a perspective of “critical distance” – or a perspective through which the observer can be critical of the target of humor. Consequently, work in the field is dominated by an assumption – whether implicit or explicit - that humor (and, especially, twentieth century American humor) necessitates that the observer disengages emotionally from the target of humor. In this project, I challenge this assumption and argue that humor has the potential to be extremely emotionally engaging. Focusing on written humor and building on both classic …

“Repeat A Little:” Time And Freedom In Deleuze’S Difference And Repetition, Mine Sak

Electronic Theses and Dissertations

In this dissertation, I examine Gilles Deleuze’s philosophy of time as presented in Difference and Repetition and use it to construct a concept of freedom, which is notably absent in his work. I argue that Deleuze’s exposition of the three syntheses of time provides significant insights for exploring the ontological possibility and structure of freedom. Through an analysis of his theory of the three syntheses of time, I investigate the meanings of agency, destiny, and choice within Deleuze's framework. I demonstrate that free choice necessitates both involuntary and creative action. Given the apparent tension between freedom and involuntariness, I explore …

The Ethics Of Involuntary Psychiatric Hospitalization: A Comprehensive Analysis Of Policies, Practice, And Ethical Oversight, Mariah Chobany

Electronic Theses and Dissertations

As a specialized field of medicine, psychiatry presents unique ethical challenges and dilemmas distinct from other medical disciplines. A particularly complex aspect of psychiatric care involves the involuntary treatment of patients who may be unable to make informed decisions about their care or participation in research due to the debilitating effects of their psychiatric condition. This presents a significant challenge for providers and researchers, particularly concerning capacity issues and the informed consent process. Despite the intricacies and complexities of ethical dilemmas in psychiatric treatment and research, there is a notable lack of comprehensive guidance in policies and practices on addressing …

Method Development Of [3 + 2] Cycloadditions Using Tertiary Amine N-Oxides And Efforts Towards The First Total Synthesis Of Chrysosporazine D, Alexander Cocolas

Electronic Theses and Dissertations

Nitrogen-containing heterocycles are ubiquitous in bioactive molecules, pharmaceutical drugs, and natural products. For this reason, finding new and efficient ways to make such compounds remains a high priority for the organic and medicinal community. Our current endeavors build upon previously established work by our group, where we generated 1,2-diamines by coupling commercially available aldehydes with trimethylamine N-oxide (TMAO) in two steps. This route proved to be effective in generating 20+ novel 1,2-diamines and imidazolidines with a demonstrated ability to undergo transformations. Using this chemistry, we have developed a diastereoselective synthesis of 50+ novel 7-azanorbornanes using tertiary amine N-oxides …

The Ethical Requirements To Avoid Clinical Error Via Safety, Augustus Nweze, Augustus Ifeanyi Nweze Fr

Electronic Theses and Dissertations

Establishing safety programs across healthcare organizations will help to eliminate clinical errors and promote patient safety goals such as culture of quality and safety. Following the 1999 IOM Report, To Err is Human: Building a Safer Health System, regarding the high rate of injuries and deaths due to medical errors, healthcare institutions and policymakers at all levels have continued to draw attention to patient safety programs. As a result, patient safety programs have been implemented nationally to avoid clinical error in healthcare. Regulatory agencies like The Joint Commission, which oversees the voluntary accreditation of hospitals in the U.S. continues to …

Efficient Development Of Density-Insensitive Near-Infrared Methods For In-Line Drug Content Monitoring In Continuous Powder Streams, Natasha L. Velez-Silva

Electronic Theses and Dissertations

A well-defined action plan to respond effectively to sudden changes in product demand is critical for preventing drug shortages within the pharmaceutical industry. An effective way to increase the output of a continuous manufacturing (CM) process is through flow rate adjustments. However, robust analytical methods must be in place to ensure consistent analytical performance across varying flow rates. Existing approaches for mitigating the physical effects of flow rate on Near-Infrared (NIR) measurements are often burdensome. Thus, efficient robust modeling strategies that reduce the current calibration burden and ensure model insensitivity to the physical variations in CM systems are needed. In …

Saudi And American Students’ Motivation And Anxiety In Online Collaborative Learning In The United States, Nawal Alqarni

Electronic Theses and Dissertations

This research study aims to explore motivation and anxiety Saudi and American students in online collaborative learning environments through online courses in U.S. universities and how they relate to their academic performance.

The study utilized a quantitative approach for data collection through an online survey of 99 Saudi students and 39 American students who were enrolled in U.S. universities. The results showed that there was no significant difference in motivation scores between undergraduate Saudi students and their American counterparts. Nor was a significant difference observed in motivation scores between graduate Saudi students and graduate American students. The data also indicated …

Investigating Anomalous Experiences In Schizophrenia Spectrum Disorders, Pavan Brar

Electronic Theses and Dissertations

The self-disorder model provides a phenomenological framework for understanding how the core symptoms of Schizophrenia Spectrum Disorders (SSDs) are rooted in an instability of minimal selfhood. This instability involves a range of ‘anomalous experiences’: transformations in an individual’s perceptual field and sense of being an agent of action. The explanatory value of this theoretical model can be summarized in two claims about the role of anomalous experiences in self-disorders: (1) anomalous experiences express a common trait-like disturbance that is characteristic of SSDs, and (2) anomalous experiences contribute to the progression of self-disorders into SSDs. Although hypotheses consistent with the first …

Teaching Video Game As A Leisure Skill To Arab American Children With Autism Spectrum Disorder Using Video Modeling In A School Setting, Lubna Alzayyat

Electronic Theses and Dissertations

Leisure activities are important in assisting individuals with autism spectrum disorder (ASD) to build relationships, learn to behave socially appropriately, and acquire new interests- competences that assist in cultivating positive self-consciousness (Specht et al., 2002; Womack et al., 2011). Statistics indicate that 2.3% of 8-year-old children in the United States are diagnosed with ASD (CDC, 2021). Despite these large numbers and the tremendous benefits of engaging in leisure activities, participation in leisure activities is lower among children with ASD when compared to their typically developing peers (Ratcliff et al., 2018). The situation is worse when compared to children with ASD …

Design, Synthesis, And Characterization Of Multi-Targeting Pyrrolopyrimidine Antifolates As Potential Single Agent Chemotherapeutic Entities, Tejashree Magdum

Electronic Theses and Dissertations

In cancer chemotherapy, the currently marketed antifolates have two major disadvantages: dose-limiting toxicities to normal tissues and susceptibility to drug resistance. These are due to their major transport by the ubiquitously expressed transporter and mutagenesis in enzymes present in cancer cells. This thesis describes an introduction, background, and research progress in antimetabolites-antifolates designed to multi-target (a) one-carbon metabolism and de novo nucleotide synthesis pathway and (b) target overexpressed transporter in cancer cells for selective tumor-targeting.

Cancer cells transport folate through three transporters: ubiquitously expressed reduced folate carrier (RFC), limitedly expressed proton-coupled folate transporter (PCFT), and folate receptors (FRs). The research …

Intrinsic Gas-Phase Behavior Of Uranium Species: A Comprehensive Reactivity Study Of [O=U≡Ch]+ And [Uh]+, Justin Terhorst

Electronic Theses and Dissertations

The intrinsic chemistry of actinide elements, particularly uranium, remains a key challenge in understanding f-block reactivity due to the complexity introduced by solvent interactions, counter-ions, and complex equilibria in the condensed phase. In this dissertation, a systematic gas-phase study utilizing preparative tandem ion-trap mass spectrometry (PTMSⁿ) is presented, focusing on the reactivity of uranium-centered species, specifically [OUCH]⁺, an oxy uranium methylidyne species, and [UH]⁺ ions. By stripping away solvent effects and isolating the ions, PTMSⁿ provides a powerful platform to probe the fundamental chemical behavior of uranium species in their intrinsic state.

The …

Perceptions Of Communication And Collaboration Between Special Education And Career And Technical Education Teachers, Alexander Novickoff

Electronic Theses and Dissertations

This dissertation explores the communication and collaboration between Local Education Agency’s (LEA) special education staff and Career and Technical Center (CTC) staff in supporting students with disabilities (SWD). Given the critical role of effective interagency communication in providing comprehensive support to SWD, this study seeks to identify the perceptions, methods, and frequencies of communication between these entities. The research is set within the context of non-comprehensive CTCs in Pennsylvania, where students split their time between their home schools and regional CTCs. Through a quantitative approach, consisting of a detailed survey distributed to both LEA and CTC staff, this study examines …

Application Of Peer-Mediated Instruction And Intervention (Pmii) To Enhance Social Interaction Skills In Early Elementary-Level Saudi Students With Autism Spectrum Disorder (Asd) In An Inclusion Setting, Inam Alghamdi

Electronic Theses and Dissertations

In Saudi Arabia, autism spectrum disorder (ASD) is on the rise, and the government is committed to improving nationwide special education services through legislative measures aimed at enhancing the flexibility of inclusion for students with ASD within school settings. However, students with ASD often encounter social challenges, especially in their interactions with peers. This increasing trend underscores the importance of implementing effective strategies to foster the social skills of these students. Evidence-based practice (EBP) is one approach that can assist in delivering services to students with ASD, proving essential for their social development. Nonetheless, limited research has been conducted on …

Neuropunk: A Discursive Ethnographic Study Of The Do-It-Yourself Transcranial Direct Current Stimulation Community, Erick Guzman

Electronic Theses and Dissertations

This dissertation seeks to understand the sociocultural contexts surrounding the do-it-yourself (DIY) use of transcranial direct current stimulation (tDCS) devices. TDCS is a non-invasive method of brain stimulation which has a history of use in (1) human brain mapping for basic neuroscience studies, (2) neuropsychological rehabilitation and the treatment of psychological disorders in clinical populations, and (3) cognitive enhancement in healthy people. However, its validity and effectiveness across these uses remain open to debate. Since the early 2010’s, tDCS has attracted a number of lay individuals interested in using it outside of formal scientific and medical contexts. These DIY tDCS …

Understanding Widowhood Cultural Practices, Values, And Beliefs, Of Nigerian American Women: An Ethnonursing Study, Prisca Anuforo

Electronic Theses and Dissertations

Introduction: Many widowhood cultural practices are detrimental to the health and well-being of widows in Nigeria. Little is known about the experiences of widowhood for Nigerian American women, their cultural practices, and how it affects their health.

Purpose: Understand widowhood cultural practices among Nigerian Americans and how these experiences may affect health and wellbeing.

Methods: The qualitative ethnonursing method was used to collect data from 25 Nigerian American widows. Data were analyzed using NVivo qualitative data manager software guided by Leininger’s four phases of qualitative analysis.

Results: Widowhood cultural practices are modified and undertaken to preserve health and honor the …

Excessive Before It Begins: A Critical Analysis Of Racialized Encounters Between Police And African American Men, Lucas Goodwin

Electronic Theses and Dissertations

In the last decade, the racial violence that plagues relations between African Americans and the police has been brought to the attention of the American public by means of cell phone video footage of police use of excessive, and at times lethal, force in encounters with African American men. The images of police brutality that have emerged in this time have outraged millions of Americans, sparking nationwide protests, as well as various social and political movements. While perspectives may abound regarding the causes and significance of such brutality, the data is clear on one thing: Police violence disproportionately harms African …

Advancing Continuous Manufacturing: The Role Of Process Analytical Technology In Process Development, Samuel R. Henson

Electronic Theses and Dissertations

The pharmaceutical industry is actively pursuing technologies which improve manufacturing processes with the goal of producing high-quality pharmaceutical products for patients, manifesting in an industry-wide investment in continuous manufacturing (CM). Process analytical technology (PAT) has been recognized for its successful monitoring of critical quality attributes during routine production and is often cited alongside CM due to its ability to make timely, in-line measurements of intermediate materials. Various PAT tools are valuable in process development, particularly as continuous wet granulation processes are developed for use within pharmaceutical manufacturing. This work applied PAT and chemometric modeling during CM process development to enhance …