Digital Commons Network^™

Antimalarials From Plant Pathogenic Fungi, Mallika Kumarihamy

Electronic Theses and Dissertations

The purpose of this study was to discover antimalarial compounds from necrotropic plant pathogenic fungi. Various phytotoxins released by necrotropic plant pathogenic fungi may inhibit the plant-like metabolic pathways in the apicoplast, a chloroplast-like organelle, essential for the survival of apicomplexan parasites, such as Plasmodium which cause malaria in humans. This dissertation describes the isolation, characterization, and biological evaluation of secondary metabolites of eight fungal strains. In addition to the antiplasmodial assay, all the extracts were subjected to phytotoxic, antimicrobial, and cytotoxic bioassays. Isolation of metabolites was performed by chromatographic methods and identification was carried out by spectroscopic and spectrometric …

How Do The Perceived Barriers, Attitudes, And Knowledge Of Grocery Store Personnel Affect Availability Of Organic Food Products?, Rachel Adams

Electronic Theses and Dissertations

Organic food is one of the fastest-growing segments of food production and consumption in the U.S. Even though organic foods are becoming more widely available, some studies suggest they may not be equally available to all populations because people in some areas are being excluded from the organics market either geographically or financially. The purpose of this study was to examine how individual and local characteristics affect the attitudes of grocery store personnel toward organic food products and how these attitudes affect availability. Grocery store personnel were surveyed about their attitudes toward organic foods, their perceptions of the barriers to …

Nutritionally Focused Drive-Thru Menus And The Impact On Consumer Preferences: A Study Of The Restaurant Industry, Meschelle M. Davis

Electronic Theses and Dissertations

More than one-third of the U.S. citizens (over 70 million people) and 16% of children are classified as obese and are at risk of many diseases including heart disease. Research indicates that 65% of Americans over the age of twenty years old are considered overweight. To address this public health issue, the U.S. Food & Drug Administration has proposed new nutritional guidelines for restaurant menus. Thus, the current study investigated the preferences of quick service restaurant (QSR) industry consumers with reference to the newly proposed U.S. Food and Drug Administration regulations. This study includes development and redesigning of drive thru …

Growing Health: Community Gardens And Their Effects On Diet, Physical And Mental Health And Community, Brittany Minnick Hanson

Electronic Theses and Dissertations

Recently, research on community gardens and their benefits to health and community has become very popular. However, this influx of research has failed to investigate challenges to successful community gardening. Some articles examine issues between community gardeners and the land owners, but other than these conflicts community garden challenges, like lack of participation and quality leadership, have not been discussed in the literature (Draper and Freedman, 2010). To allow future gardens to be as successful as possible it is important to identify potential obstacles. Additionally, it is just as important to continue to examine possible benefits, for example, physical activity …

Age As A Factor In Inter-Tissue Spacing Of Stable Carbon Isotope Values In Juvenile Human Remains From The Dakhleh Oasis, Egypt, Annie Laurie Norris

Electronic Theses and Dissertations

Although stable isotope analysis is routinely utilized in bioarchaeology and relies on principles that are well-understood, there are still fundamental issues that have not been thoroughly investigated. This thesis examines the relationship between inter-tissue spacing of carbon stable isotope values (δ13C) and age in juvenile human remains. Analyses of tissues within the same individual reveal disparate isotopic values for a variety of physiological and biological reasons discussed herein. This project examines the distance between the δ13C values in bone collagen, skin, hair, and nail, and examines how these distances vary between different age groups, utilizing data collected from 52 well-preserved …

Effect Of Predation Risk And Food Availability On Parental Care And Nest Survival In Suburban And Wildland Florida Scrub-Jays, Joseph M. Niederhauser

Electronic Theses and Dissertations

Individual organisms often use cues from their natural environments to determine many behavioral and life-history "decisions." These "decisions" are usually adaptive, i.e. a response to selection, because the environmental cues on which they are based reliably correlate with increased fitness over time. When the selected behavioral response to a natural cue no longer provides a fitness benefit, then selection for a new response may occur but individuals maintaining the previously selected response may suffer reduced survival and reproduction. Especially in human-modified landscapes individuals making a maladaptive behavioral or life-history choice based on those formerly reliable environmental cues may be faced …

Rock-A-Buy Baby: Consumerism By New, First-Time Mothers, Sara Afflerback

Electronic Theses and Dissertations

Rock-a-Buy Baby: Consumerism by New, First-Time Mothers, is the first known sociological exploration of need-based consumption for babies, despite the baby gear industry being a $6-billion-dollar business (whattoexpect.com). Data stemmed from qualitative, semistructured interviews with new, first-time mothers (3 months – 1 year postpartum) conducted within participants‘ households. The insights gained from the present study tell us a great deal about the ―needs‖ that predominantly white, middle-class mothers socially constructed in anticipation of their first child, and the consumptive behaviors used to accomplish these "needs." Respondents had turned to similar resources (other mothers, online forums, consumer reports, books, magazines, etc.) …

An Exploratory Study Of Physiologic Responses To A Passive Exercise Intervention In Mechanically-Ventilated Critically Ill Adults, Christina M. Amidei

Electronic Theses and Dissertations

Muscle weakness is the most common and persistent problem after a critical illness. Early mobilization of the critically ill patient, beginning with passive exercise and progressing to ambulation, may mitigate muscle effects of the critical illness. However, mobilization may produce adverse effects, especially early in the illness when risk for physiologic deterioration is common. If safe, introducing a mobility intervention early in the illness may facilitate ventilator weaning, shorten intensive care unit and hospitals stays, and improve functional status and quality of life for mechanically ventilated critically ill patients. The aim of this study was assess the cardiopulmonary and inflammatory …

Perceptions Influencing School Nurse Practices To Prevent Childhood Obesity, Susan Quelly

Electronic Theses and Dissertations

Approximately one-third of children in the United States are overweight or obese with increased risks for numerous physical and psychosocial comorbidities. Schools are ideal environments to address this serious health crisis and school nurses are uniquely positioned qualified healthcare providers to actively participate in childhood obesity prevention (COP). A review of the literature provided findings to identify a gap in the knowledge regarding the association between school nurse COP perceptions and practices. A modified theoretical framework based on Bandura’s health promotion by social cognitive theory guided this study. The purpose of this study was to identify the key perceptions (self-efficacy, …

The Foods And Crops Of The Muisca: A Dietary Reconstruction Of The Intermediate Chiefdoms Of Bogota (Bacata) And Tunja (Hunza), Colombia, Jorge Luis Garcia

Electronic Theses and Dissertations

The Muisca people of the Eastern Cordillera of Colombia had an exceptionally complex diet, which is the result of specific subsistence strategies, environmental advantages, and social restrictions. The distinct varieties of microclimates, caused by the sharp elevations in this part of the Andes, allows for a great biodiversity of plants and animals that was accessible to the native population. The crops of domesticated and adopted plants of the Muisca include a wide variety of tubers, cereals, fruits, and leaves that are described in detail in this thesis. The Muisca used an agricultural method known as microverticality where the different thermic …

Stable Isotopes And Multiple Tissue Analysis: Reconstructing Life Histories For Individuals From Dakhleh Oasis, Egypt, Noel Johns

Electronic Theses and Dissertations

Stable isotope analysis is often used to evaluate elements of the lives of past peoples, such as diet and health status, at a societal level. Analysis at an individual level is exceptionally rare, and has not been conducted using a variety of tissues representing both early life and life approximate to death. In this study, δ 13C and δ15N isotope signatures are used to create life histories for single individuals from Romano-Christian period Kellis 2 cemetery in the Dakhleh Oasis, Egypt. Samples are obtained from several different tissues, including tooth dentin, bone collagen, hair, nail, skin, and gut content, all …

The Effects Of Phosphatidylserine On Reaction Time And Cognitive Function Following An Exercise Stress, Adam John Wells

Electronic Theses and Dissertations

Phosphatidylserine (PS) is an endogenously occurring phospholipid that has been shown to have cognition and mood enhancing properties in humans, possibly through its role as an enzyme co-factor in cellular signal transduction. Specifically, PS has been identified as activator of classical isoforms of protein kinase C, an enzyme known to be involved in the growth and differentiation of neural cells, and is therefore thought to play a role in the protection of neurons. The purpose of this study was to examine the effects of supplementation with PS and caffeine on measures of cognition, reaction time and mood prior to and …

Phosphatidic Acid Increases Lean Body Tissue And Strength In Resistance Trained Men, David Williams

Electronic Theses and Dissertations

Phosphatidic Acid (PA) is a natural phospholipid compound derived from lecithin which is commonly found in egg yolk, grains, fish, soybeans, peanuts and yeast. It has been suggested that PA is involved in several intracellular processes associated with muscle hypertrophy. Specifically, PA has been reported to activate protein synthesis through the mammalian target of rapamycin (mTOR) signaling pathway and thereby may enhance the anabolic effects of resistance training. To our knowledge, no one has examined the effect of PA supplementation in humans while undergoing a progressive resistance training program. To examine the effect of PA supplementation on lean soft tissue …

This Is Just Temporary: A Study Of Extended-Stay Motel Residents In Central Florida, Stephanie Guittar Gonzalez

Electronic Theses and Dissertations

Motel life has existed in the United States for over 100 years. However, it was not until the HEARTH Act in 2009 changed the federal definition of homelessness that those who live in motels more or less permanently were considered homeless persons. This project utilizes qualitative, semi-structured interviews with 18 families with children who are living in motels to explore their experiences with motel life and social service providers, their housing identity, and identity management strategies. Findings show that most of the motel residents did not identify with the conventional definition or image of homelessness and instead negotiated the term …

Front-Line Registered Nurse Job Satisfaction And Predictors: A Meta-Analysis From 1980 - 2009, Deborah Anne Saber

Electronic Theses and Dissertations

Front-line registered nurses (RNs) make up the workforce that directly affect the care of patients in a variety of different healthcare settings. RN job satisfaction is important because it is tied to retention, organizational commitment, workforce safety, patient safety, and cost savings. The strongest predictors have been difficult to determine because workplaces differ, numerous tools to measure satisfaction exist, the workforce is diversified by generations and work positions, and ongoing policy changes directly impact the work of the front-line RN. The strength and stability of the workforce depends on an accurate understanding of the predictors of job satisfaction for the …

Somatechnologies Of Body Size Modification: Posthuman Embodiment And Discourses Of Health, Meghan Griffin

Electronic Theses and Dissertations

This project focuses on persistent gaps in philosophies of the body: the enduring mindbody divide in accounts of phenomenology, the unfulfilled promises of representing and inhabiting the body in online and virtual spaces, and the difference between health as quantified in medical discourse versus health as lived experience. These tensions are brought to light through the electronic food journal genre where the difficulty in capturing pre-noetic, outsideconsciousness aspects of experience and embodied health are thrown into relief against circulating cultural discourses surrounding health, body size, self-surveillance, and self-care. The electronic food journal genre serves as a space for users to …

Entry Age And Reading Level By The End Of Third Grade., Tony Lynn Dalton

Electronic Theses and Dissertations

This study was conducted to see if a difference exists in the mean Dynamic Indicators of Basic Early Literacy Skills: Oral Reading Fluency scores of students who entered kindergarten as 4 year olds, 5 year olds, and 6 year olds inclusively. Specifically, this dissertation considered the possibility that holding children out of kindergarten an extra year increased their reading level, while sending children to school too young delayed their ability to read and comprehend.

A quantitative study was used to find differences between the mean reading levels at the end of 3rd grade for students who entered kindergarten on or …

The Influence Of Time Perspective On Physical Activity Intentions And Behaviors Among Adolescents Residing In Central Appalachia., Tauna Gulley

Electronic Theses and Dissertations

Obesity and inactivity are prevalent among central Appalachian adolescents. Appalachian residents have been labeled "fatalistic," a time perspective unsupportive of health-promoting behaviors such as regular participation in physical activity. The theory of planned behavior has been used extensively to explain the physical activity behaviors of adolescents. Constructs within the theory of planned behavior include attitudes toward the behavior, subjective norms, perceived behavioral control, and intention to perform the behavior. The purpose of this study was to determine the time perspective of central Appalachian adolescents and examine the relationship between time perspective and the constructs within the theory of planned behavior. …

Determination Of Select Metal Ions In Commercially Available Conventional And Organic Baby Foods., Neva S. Winters

Electronic Theses and Dissertations

The goal of this study is to determine whether or not there is an appreciable difference between concentrations of various metal ions present in conventionally grown and processed and organically grown and processed baby foods. Two prominent, commercially available brands were chosen to undergo comparative studies between both their own conventional and organic varieties of second stage green beans and carrots. Samples were tested for cadmium, calcium, iron, lead, nickel, and zinc. Two containers of each variety of baby food were sampled in triplicate, with purchases of foods being made in separate areas to ensure that each set came from …

Pedometers Accelerometers And Observational Methods: A Comparison Of Measurements Of Physical Activity In Fourth-Grade Students., Amanda E. Greene

Electronic Theses and Dissertations

In recent years physical inactivity among students has become a matter of great concern. Nearly 65% of students do not meet the daily recommended level of physical activity, which is 60 minutes or more of moderate to vigorous physical activity each day, with 50% of that time being spent in moderate to vigorous levels of activity (CDC, 2010b). As a result, the 21^st century has shown to be a time of many health problems such as, obesity, diabetes, and heart disease. In fact, nearly one third of all children are considered obese or overweight (Slawta & DeNeui, …

The Induction Of Positive Affect In A Community Setting Using Electronic Communications., Philip Andrew Smeltzer

Electronic Theses and Dissertations

Objective: To evaluate the influence of positive affect inductions on daily and weekly Positive and Negative Affect Scales (PANAS) in a community setting. Methods: Humor messages were distributed to participants four times per day during a treatment week with general health messages distributed in the crossover week. Subjects completed a series of self-report psychosocial and behavioral survey instruments on a weekly basis and daily PANAS responses. Messages were delivered through either email or SMS/text messages. Results: The daily and weekly PANAS scores were higher during treatment periods compared to the neutral periods. The observed trends were suggestive of successful positive …

Characterization Of The Ai-2-Dependent Quorum Sensing Pathway In Aggregatibacter Actinomycetemcomitans., Elizabeth A. Novak

Electronic Theses and Dissertations

Quorum sensing in the oral pathogen Aggregatibacter actinomycetemcomitans is dependent upon the soluble signaling molecule AI-2, but it is not known how the initial detection of AI-2 is coupled to the downstream regulation of gene expression that confers complex phenotypes such as biofilm formation and iron acquisition. Here we show that expression of a two-component system encoded by qseBC is induced by AI-2 in A. actinomycetemcomitans and that induction of qseBC requires the AI-2 receptors, LsrB and/or RbsB. Inactivation of the sensor kinase gene qseC resulted in a significant reduction of in vitro biofilm growth and in vivo virulence using …

Regulation Of Morphogenesis By Ammonium Transporters In Ustilgo Maydis., Jinny A. Paul

Electronic Theses and Dissertations

Many species of fungi undergo a dimorphic transition to switch from a unicellular yeast-like growth form to a filamentous growth form. Ustilago maydis undergoes such a transition, in response to successful mating events and subsequent host cues, to form a filamentous pathogenic form. U maydis also undergoes haploid filamentous growth in response to several environmental cues including, but not limited to nutrient limitation, pH, lipids, among others. Ammonium transporter proteins (Amts) play an essential role in controlling the dimorphic transition in response to nutrient limitation, specifically nitrogen in the form of ammonium. I demonstrate a role for the U maydis …

Narrative Comprehension Abilities Of Children From Low-Income Families : Role Of Temperament, Attention Skills, And Cognitive Engagement., Tara N. Weatherholt

Electronic Theses and Dissertations

The current study investigated narrative comprehension ability in children from low-income families by examining the contributions of temperament, attention skills, and cognitive engagement. Research has identified narrative comprehension skills as significant for successful literacy outcomes, but few studies have examined the effect of individual level characteristics on comprehension ability. As reading and pre-reading skills in children from disadvantaged homes has been shown to be lower than that of children from more privileged backgrounds, it is critical to examine the factors that contribute to comprehension skills in this population. The current study focuses on the relationships among temperament, attention network skills, …

Pharmacists As Mid-Level Healthcare Providers And The Clinical Results Of A Pharmacist-Led Diabetes Disease Management Program., Benjamin Maurice Risner 1983-

Electronic Theses and Dissertations

Advancements in medical therapy have augmented resources available to physicians to treat disease and, because of this, spending on prescription drugs has doubled in the past decade. Increasingly, clinical trials are demonstrating the benefits of aggressive disease management in reducing morbidity and mortality. Physicians treating patients with chronic conditions must balance the benefits of combination drug therapy against the risk of adverse drug events and drug interactions. For instance, evidence-based practice guidelines in patients with diabetes and multiple comorbidities require combination therapy in order to reduce morbidity and mortality. Patients with polymorbidity require the attention of multiple physicians, further fragmenting …

Feeding Practices Of Mothers In The Gobi Desert Of Mongolia, Julie F. Tate

Electronic Theses and Dissertations

The diets of Mongolia infants are deficient in vitamins and minerals and complementary foods are introduced too early. Breastfeeding is the best source of nutrition for infants until 6 months of age. A survey of 50 Mongolian mothers with children under the age of 5 in the town of Sainshand, Dornogobi, was conducted in July 2011. Mongolian infants are among the highest percent of infants in the world who are exclusively breastfed for the first 6 months of their lives, thus providing them with excellent nutrition. However, complementary feedings and supplements are not appropriately used or understood. Therefore, the diets …

Transmission Linked To Structural Vulnerability: How Low-Income Countries Endured The Great Recession, Rachel F. Hartgen

Electronic Theses and Dissertations

The implosion of the 2008 financial crisis ignited fears that integration would transmit the crisis’ effects throughout the global system. Examining two countries, Bangladesh and Zambia, this project shows that low-income countries with relatively little integration also saw negative impacts. This occurred through three main transmission mechanisms: trade flows, rising prices and financial flows that could have possible long-term effects at the macro and micro level. The manner and impact of each transmission mechanism, however, varied among LICs according to each country’s individual structural economic and financial vulnerabilities. Bangladesh saw a delayed impact but did not avoid the crisis completely, …

The Creation Of Art Books With Adolescents Diagnosed With An Eating Disorder: Effectiveness, Self-Esteem, And Related Factors, Eileen Chaves

Electronic Theses and Dissertations

This pilot study undertook a mixed methods exploration of the interaction of art therapy and self-esteem in an adolescent eating disorder population. Using therapeutic art books in a group format, adolescents created art about their feelings, their eating disorder, or whatever else they deemed important. This art technique is relatively new and novel as an art therapy intervention. Therefore, this study aimed to look at the technique's effectiveness at decreasing participants' negative mood states and investigated the technique's ability to affect participants' perceptions of their self-esteem. Measures of global self-esteem and art therapy related self-esteem were measured using the Rosenberg …

Extreme Variation In The Sagittal Crest Of Tapirus Polkensis (Mammalia Perissodactyla) At The Gray Fossil Site Northeastern Tn., Aaron Randall Abernethy

Electronic Theses and Dissertations

The preservation and quantity of fossil tapirs (Tapirus polkensis) from the Gray Fossil Site in northeastern Tennessee provides a unique opportunity for comparison and analysis of skeletal characters. Intraspecifically, modern tapirs show little to no variation in the morphology of the sagittal crest. However, several different morphologies exist within the sample at Gray. No osteological evidence of sexual dimorphism exists for tapirs, and no correlation between crest shape and sex was observed. Several juveniles display well defined crests, while some adults have only minor thickening of the temporal ridges; therefore, no distinct correlation between age and crest state …

Classroom Placement Of Twins Triplets And Other Multiples In Grades Kindergarten Through Eight In East Tennessee Schools: East Tennessee Principals Perceptions., Joy Brown Parton

Electronic Theses and Dissertations

The purpose of this study was to learn from kindergarten- through 8th-grade principals in East Tennessee (a) what policies guide their decisions regarding classroom placement for multiple-birth children; (b) what postsecondary training they have; (c) what sources guide their decisions; (d) what knowledge they have of the needs, relationships, and bonds of multiples; and (e) what their perceptions are regarding how to best meet the needs of multiples.

Data were collected through interviews with a purposeful sample of 10 principals of kindergarten- through 8th-grade schools. Five themes emerged forming constructs for organizational framework: (a) learning environment, (b) meeting individual needs, …