Digital Commons Network^™

Healthy Eating Opportunities And Choices For University Faculty, Selby Rebecca Entrekin

Electronic Theses and Dissertations

College food environments can be obesogenic settings due to the availability of fast food restaurants and buffet style cafeteria’s accessible to the university community. These environments often foster eating behaviors that can contribute to rising obesity rates in the United States. The aim of this study was to identify university faculty’s perceptions of the campus food environment and access to healthy foods. Investigated were barriers to making healthy food choices on campus and strategies ion how to provide and encourage better food choices. Questions were developed to identify barriers, perceptions, and solutions to improve the healthy eating environment on campus. …

The Impact Of A Fruit And Vegetable Intervention On School Cafeteria Fruit And Vegetable Selection And Consumption In A Rural, Appalachian Mississippi Elementary School, Michelle Weber

Electronic Theses and Dissertations

Fruit and vegetable intake for children in the United States is low, which puts them at risk for poor health in the future. The National School Lunch Program meal pattern and nutrition standards for participating schools include increased fruits and vegetables, compared to previous standards. Using a pretest-posttest design, this study examined the effect of a fruit and vegetable intervention on fruit and vegetable food selection and consumption in a rural, Appalachian Mississippi elementary school. A six-week intervention (nutrition education, cafeteria tastings, fruit and vegetables for home usage/backpack program) was implemented. The unannounced fruit and vegetable selection and waste measurements …

Increasing Teacher Retention: An Applied Research Study On The Effects Of Mentoring And Culture In The Abc County School District, Jimmy Holland Weeks

Electronic Theses and Dissertations

This applied research study sought to improve the retention rate of beginning teachers through a teacher mentoring program. The need for the teacher retention rate to improve became evident as student achievement fell, new teacher training costs increased, and fewer new teachers entered the teaching profession. Using four elements in this study, mentoring, job-embedded coaching, individual growth plan, and culture development, the program sought to better support new teachers during the first few years of their careers. Surveys, evaluations, collaboration logs, and professional growth plans were used in the study. The findings revealed improvement in the teacher retention rate in …

Implementing Mass Spectrometry For The Structural And Compositional Analysis Of Proteins, Mohammad Riaz

Electronic Theses and Dissertations

Lectins are sugar-binding proteins that perform various biological functions such as cellular recognition attachments etc. Pulses the dried edible seeds of certain plants are great sources of lectins and a proteomics approach directed at lectins identification would bring substantial improvement in the lectin identification process. Lectins from nine different plant species were analyzed through SDS-PAGE and proteomics analysis. After LC-MS/MS analysis proteins were identified with protein database searches using Uniprot. Functionally uncharacterized proteins were identified with database searches were annotated with the Pfam and NCBI-CCD databases. In-vitro pharmacological screening will be carried out to assess the pharmacological effects of these …

Agronomic And Quality Response Of Hard Red Spring Wheat Genotypes To Management Systems In South Dakota, Jonathan Kleinjan

Electronic Theses and Dissertations

Intensive cereals management techniques such as multiple fungicide applications and in-season split N applications have been used to successfully improve wheat yields in Europe and in some winter wheat production areas of the USA. However, research on the effects of these management practices and their interaction with genotypes is limited in the hard red spring wheat (HRSW) production areas of the USA. The objectives of this study were to: (i) compare management treatments and (ii) quantify any interaction effects between management and genotype on the agronomic characteristics and relevant flour and dough properties of locally-adapted HRSW genotypes. A randomized complete …

Impact Of Concussion And Orthopedic Injuries On Physical Activity And Quality Of Life After Sport Retirement, Makenna Hancock

Electronic Theses and Dissertations

CONTEXT: Concussions and orthopedic injuries represent a significant risk related to participation in collegiate athletics. These injuries can create significant long-term impairments and functional limitations which may also decrease former athletes’ quality of life (QoL) and inhibit their ability to engage in physical activity. OBJECTIVE: To investigate QoL and physical activity levels of former collegiate athletes with a history of concussion and orthopedic injury, orthopedic injury only, and healthy controls. DESIGN: Descriptive, experimental study.
SETTING: Daily life as former National Collegiate Athletic Association Division I collegiate athlete.
PARTICIPANTS: Former Division I collegiate athletes competing in football, women’s soccer, baseball, softball, …

Production And Storage Stability Of High Concentrated Micellar Casein And Its Effect On The Functional Properties Of Process Cheese Products, Ahmed Hammam

Electronic Theses and Dissertations

Micellar casein is a high-protein ingredient that can be used in process cheese products (PCP) formulations. PCP is a dairy food prepared by blending dairy ingredients (such as natural cheese, protein concentrates, butter, non-fat dry milk NFDM, whey powder, and permeate) with nondairy ingredients (such as sodium chloride, water, emulsifying salts, color, and flavors) and then heating the mixture with a continuous agitation to produce a homogeneous product with an extended shelf-life. The first objective of this study was to produce a highly concentrated micellar casein (HC-MC) and evaluate its storage stability. Skim milk was pasteurized at 76°C for 16 …

A Bioinfomatic Analysis Of Luminal And Mucosal Ileal Bacteria Colonizing Nursery Pigs Fed Different Protein Sources, Jamie L. Ortman

Electronic Theses and Dissertations

Weaning is a critical time in a young pig’s life that will greatly impact its adult growth and development. The objective of this research was to evaluate the effects of various protein sources on the bacterial composition within luminal and mucosal populations in simple and complex diets to gain a better understanding of factors influencing gut health. Weaned pigs were fed 1 of 3 simple experimental diets: 1) basic diet containing corn and soybean meal (Negative Control - NEG), 2) basic diet + fishmeal (FM; Positive Control - POS), and 3) basic diet + microbially-enhanced soybean meal (MSBM). Phase I …

Does Medicaid Increase Emergency Room Use: Evidence From Oregon Health Program?, Md Fourkan

Electronic Theses and Dissertations

This thesis paper strives to identify the relationship between Medicaid expansion and Emergency Department use. I use a Monte Carlo simulation for demonstrating the endogeneity problem and a copula model using the Oregon Health Program (OHP) data to show the previous literature has exaggerated the causal relation between Medicaid expansion and Emergency Department use. This paper can be divided into two parts. First, it tries to focus on the under-identification of multiple endogenous variables problem in typical econometrics papers, where researchers correct for a single endogenous variable but intentionally or unintentionally ignore the endogeneity of one or more other independent …

Factors Influencing Nurse Practitioners' Weight Management Practices In Primary Care, Suzanne Hyer

Electronic Theses and Dissertations

More American adults are overweight or obese than ever before. Nurse practitioners (NPs) play a critical and expanding role in primary care, which is an ideal setting for the assessment and management of weight loss. NPs can make a significant contribution to tackling the obesity crisis. The study presented here seeks to close the gap in data related to how NPs approach weight management with their primary care patients. This study focused on a comprehensive examination of the current practice patterns of NPs related to weight management, a theoretical concept analysis of weight bias among healthcare providers, along with the …

The Sustained Impact Of Prekindergarten Participation On Third Grade Academic Performance, Marissa Melin

Electronic Theses and Dissertations

In this study, the researcher investigated whether the impact of participating in a prekindergarten program on academic achievement persists through third grade. The study compared three groups of students: students who participated in voluntary prekindergarten, private prekindergarten, and students who did not participate in any prekindergarten program. Using a series of two-factor multivariate analyses of variance (MANOVAs), this investigation found no interaction effects among prekindergarten participation and race, gender, socioeconomic status, presence of a discipline referral, or chronic absenteeism on academic achievement in the third grade. However, there was a main effect for the type of prekindergarten program on academic …

An Investigation Of The Appropriateness Of The English Language Learner Accountability Mark Established By The Every Student Succeeds Act Of 2015, Francisco Rivera

Electronic Theses and Dissertations

This quantitative study sought to disclose and describe differences in academic performance between English language learners (ELLs) and non-English language learners (non-ELLs) in grades sixth, seventh, and eighth during the two-year period of 2016 – 2018. A two-year period was utilized because of the two-year ELL accountability mark established by the Every Student Succeeds Act (ESSA) of 2015. The study used i-Ready diagnostic data, in both mathematics and reading, as the performance measures, and used ACCESS for ELLs (WIDA) tier scores (i.e., WIDA Tier A, WIDA Tier B, and WIDA Tier C) to identify the level of English language acquisition …

A Comparison Of Self-Service Technologies (Ssts) In The U.S. Restaurant Industry: An Evaluation Of Consumer Perceived Value, Satisfaction, And Behavioral Intentions, Motaz Zaitouni

Electronic Theses and Dissertations

Innovation in technology has been growing rapidly in recent years. Many restaurants have been utilizing different types of self-service technologies (SSTs) to enhance their operations and customer satisfaction. Despite, the rapid spread of SSTs in the restaurant industry, very limited empirical research has been conducted to evaluate the influence of SSTs type on customer dining experience. Therefore, the purpose of this dissertation was to examine the SSTs values that influence restaurant customers' satisfaction and their decision to continue to reuse SSTs. More specifically, this study utilized the Theory of Consumption Values (TCV) to examine consumers' perception of the SST values …

Community Pharmacists And Substance Use Disorders: Attitudes, Knowledge And Practices, Deepika Rao

Electronic Theses and Dissertations

Background: Substance use disorder (SUD) is a serious health concern affecting a large proportion of the US population. Community pharmacists are well-positioned to prevent, screen, and provide appropriate treatment for SUD. Stigma towards these patients and SUD results in reduced quality of care as well as poor treatment outcomes. It is imperative that pharmacists have the appropriate knowledge of and attitude towards prevention, harm reduction and treatment to develop therapeutic relationships and improve their delivery of pharmacy services

Objective: To assess knowledge, practices (with an emphasis upon screening), stigma and general attitudes of community pharmacists towards SUD and evaluate the …

Access To Care And The Use Of Healthcare Services By Women In Rural Cameroon: A Participatory Action Research Study, Grace Tadzong-Awasum

Electronic Theses and Dissertations

Women in rural Cameroon do not access health care as timeously and as often as they should. They fail to get screened for common diseases, with the consequence that such diseases are often diagnosed at a very advanced stage. This accounts for the high morbidity and mortality rates as well as low life expectancy recorded among women. The purpose of this study was to explore and understand the health access experiences of women in rural Cameroon. Methodology: Participatory action research was used guided by a Focused ethnography in phase one. Twenty-five women aged 21-77 years were recruited through local the …

Harnessing The Anopheles Microbiome To Conditionally Express Anti-Plasmodial Effectors During The Blood Meal, Jackie Shane

Electronic Theses and Dissertations

The control of vector-borne diseases such as malaria has been an extremely important research subject for hundreds of years. Because of the complex lifecycles of the pathogens that cause these diseases, finding a comprehensive treatment or preventative strategy has proven extremely difficult. Malaria alone is responsible for almost half a million deaths annually, most of them children under 5 years old. This disease is caused by parasitic protists in the genus Plasmodium that are transmitted to humans from Anopheles sp. mosquitoes. Most preventative strategies that are in use today revolve around controlling the vectors, including bed nets, insecticides, and larval …

Probiotic Use In Trauma Patients: A Pathway To Determining The Standard Of Care To Improve Outcomes, Heather Vitko

Electronic Theses and Dissertations

The gut microbiome consists of normally non-pathogenic bacteria, viruses, and fungi. These friendly microbes serve to maintain GI barrier function and integrity, play a role in host nutrient and drug metabolism, immunomodulation, and prevent pathogenic bacteria from colonizing or causing disease. The importance of a healthy microbiome for the overall health of the host is just recently being appreciated within the medical and science communities. Disruption of the microbiome places one at greater risk for illness and infection. Patients who suffer a traumatic injury are among those at highest risk for complications associated with microbial imbalance, or dysbiosis. In addition …

Using An In Vitro-In Vivo Correlation For The ‘Bioequivalence By Design’ Development Of An Immediate Release Carbamazepine Product, Douglas Steinbach

Electronic Theses and Dissertations

The quality of a drug product may be characterized by the consistency with which its indicated clinical effect, and safety profile, is experienced by the patient. The concept that such quality should be built into a product is at the core of the United States Food and Drug Administration’s (FDA) quality by design (QbD) initiative. This vision for pharmaceutical product development emphasizes the risk-based identification of critical quality attributes (CQA) which summarize a product’s performance, the efficient refinement of critical product/process parameters (CPP) that can affect such attributes, and the systematic development of CPP limits, which assure appropriate performance of …

The Association Between Depression, Anxiety And Clinical Outcomes For Type 2 Diabetes Mellitus, Elham Heidari

Electronic Theses and Dissertations

Objective: To evaluate the impact of depression and/or anxiety on clinical outcomes of diabetes, including glycosylated hemoglobin (HgA1c), blood glucose, blood pressure, total cholesterol, weight and LDL among patients with incident type 2 diabetes mellitus (T2DM).

Method: A retrospective cohort study utilizing electronic medical record (EMR) data from a primary care physician (PCP) group practice was conducted to identify patients newly diagnosed with T2DM with at least 6 months pre-diagnosis and 12 months post-diagnosis of EMR data using International Classification of Disease 9th edition Clinical Modification (ICD-9-CM) coding. The presence of comorbid depression and anxiety was identified to identify four …

Synthesis Of Novel 6-Substituted And 5-Substituted Pyrrolo[2,3-D] Pyrimidine Antifolates As Targeted Anticancer Therapies, Xinxin Li

Electronic Theses and Dissertations

The dissertation will give an introduction, background and current research progress in the areas of antifolates and chemotherapy of anticancer. The design and synthesis of classical 6- substituted pyrrolo[2,3-d]pyrimidines and 5-substituted pyrrolo[2,3-d]pyrimidines as potential antifolates have been described. The design variations include: methylated thiophene regioisomers, fluorinated phenyl regioisomers, thionyl regioisomers on the side chain of pyrrolo[2,3-d]pyrimidines. As a part of this study, a series of new compounds have been synthesized and characterized. Of these, ten final compounds were submitted for biological evaluation.

An Exploratory Survey Of Factors Affecting Satisfaction With Educational Experiences For Parents Of Children With Cystic Fibrosis, Rebecca Perry Keenan

Electronic Theses and Dissertations

Consumer satisfaction has been studied extensively as it relates to service seeking behavior, positive perceptions of services rendered, and measurable benefit as a result of service delivery. Furthermore, numerous studies have explored the importance of a strong, collaborative home-school partnership for student success. Additionally, previous research has identified children with chronic illnesses as a special population frequently requiring individualized accommodations and modifications to promote success in the educational environment, and therefore testing the limits of the educational system to adequately meet their needs. Finally, research has described the common sequelae of Cystic Fibrosis, including wide-ranging physical, behavioral, and functional consequences. …

An Ethical Model For Mandatory Reporting To Avoid Preventable Adverse Harm In Health Care, Kate A. Molchan

Electronic Theses and Dissertations

The goal of the dissertation is to undertake an analysis in healthcare ethics that focuses upon organizational ethics to resolve problems related to medical error in the U.S. The ethical argument focuses upon justifying a model of mandatory reporting nationally. While countless others have argued in favor of the implementation of a mandatory reporting system, this dissertation presents its model through the lens of organizational theory; arguing first that healthcare organizations are ethically required to invest in patient safety. This premise frames the foundation for this dissertation's central argument; namely, that U.S. healthcare organizations have an ethical imperative to protect …

The Role Of Cathelicidin In The Regulation Of Gut Microbiota And Inflammasome Activation In Alcoholic Liver Disease., Fengyuan Li

Electronic Theses and Dissertations

Alcoholic liver disease (ALD) is characterized by gut dysbiosis and hepatic and intestinal inflammation. Gut microbiota is critically maintained by antimicrobial peptides (AMPs) expressed in the epithelial and immune cells. AMPs are also identified as immune-regulators in various diseases. Previous studies demonstrated that deficiency of AMPs REG3 lectins exacerbated alcoholic steatohepatitis. LL-37 is the sole member of human cathelicidin AMP family, named CRAMP in mouse. Despite of the extensive studies in infectious diseases and in gut-microbiota-related inflammatory bowel disease, the role of LL-37/CRAMP in ALD is yet unknown. Our previous studies showed a decreased intestinal CRAMP in a mouse model …

Physical Education Activity Courses: An Exploration Of How Enrollment Influences Student Retention Rates., Dylan J. Naeger

Electronic Theses and Dissertations

Nationally, student retention rates continue to be a problem, as the National Center for Education Statistics (2018) found the six-year undergraduate graduation rate for students who started college in fall 2010 was around 60%. An area not yet investigated is if any association exists between enrollment in a university physical education activity course (BIP) and academic success. The purpose of this study was to determine how enrollment in a BIP course affected undergraduate student retention rates. This study examined whether enrollment in BIP courses influenced student retention of all first-time, full-time, baccalaureate degree-seeking students enrolled at a public research university …

Effects Of Hydrogen Sulfide In Hyperhomocysteinemia-Mediated Skeletal Muscle Myopathy., Avisek Majumder

Electronic Theses and Dissertations

Although hyperhomocysteinemia (HHcy) occurs due to a deficiency in cystathionine-β-synthase (CBS), causing skeletal muscle myopathy, it is still unclear whether this effect is mediated through oxidative, endoplasmic reticulum (ER) stress, both or something else. Cystathionine γ-lyase (CSE) and CBS are the main H₂S producing enzymes, which produce Hydrogen sulfide (H₂S) from Hcy in the transsulfuration reaction. H₂S is an anti-oxidant compound and patients with a CBS deficiency cannot produce enough H₂S, thus rendering them vulnerable to excess Hcy-mediated damage. Both in-vitro (C2C12 cells) and in-vivo (CBS+/- mice) models were used to …

Lead And Crime: An Ecological Study Between Lead Contaminated Topsoil And Violent Crime., Brian Guinn

Electronic Theses and Dissertations

Lead is a known neurotoxicant. Human exposure to lead comes primarily through environmental exposures, including remnant lead paint, lead contaminated topsoil and lead contaminated water. Prenatal and early life lead exposure has been associated with numerous neurocognitive and neuropsychiatric disorders. This dissertation presents findings from an ecological study which evaluated the geospatial association between topsoil lead content and the incidence of FBI designated violent crime in Jefferson County, Kentucky. A total of 412 topsoil samples were collected along roadways (n=300) and from Louisville Metro Parks (n=112). Jefferson County crime data was obtained from the Louisville Metro Police Department – Crime …

Association Between Cigarette Smoking And Ovarian Reserve Among Women Seeking Fertility Treatment With Effect Modification By Race And Nat2 Genotype., Islamiat A. Oladipupo

Electronic Theses and Dissertations

Cigarette smoking in women has been associated with adverse reproductive outcomes such as reduced ovarian reserve, poorer in vitro fertilization (IVF) outcomes and increased adverse pregnancy outcomes. This study examined the association of smoking with ovarian reserve in a cross-sectional study of women seeking fertility treatment, and potential effect modification by race and NAT2 acetylator phenotype. Data from 265 women from the Louisville Tobacco Smoke, Genetic Susceptibility, and Infertility (LOUSSI) Study were analyzed. A total of 265 women were recruited through a single infertility clinic between September 2016 and June 2018. Information on current smoking status was assessed using a …

Assessing The Affects Of Treatment Services, Financial Assistance, Race/Ethnicity, And Income On The Criminal Justice Outcomes Of Women On Probation., Jordan Wilfong

Electronic Theses and Dissertations

The aim of this study is to examine the affect that treatment services have on the criminal justice outcomes of women on probation. The research to date on the treatment services provided to the criminal justice population has tended to focus on prisoners rather than probationers, with even fewer studies that include samples of women on probation. This study will investigate the impact on criminal justice outcomes of services intended to treat issues identified to increase recidivism among female probationers, such as substance use disorders, illicit drug use, mental health issues, and poverty. An additional assessment is conducted to determine …

The Regional Distribution And Molecular Interactions Of Phospholipids And Glucose In Mammalian Vitreous Humors., Abigail Nicole Schnepf

Electronic Theses and Dissertations

The vitreous humor (VH) is located in between the lens and the retina. It is composed of 98% water, hyaluronan (HA), collagen, proteins, phospholipids (PLs), and other metabolites. With aging, the VH undergoes liquefaction, a process that causes the gel-like structure of the VH to turn into a liquid and can lead to serious ocular diseases, including retinal detachment, vitreal detachment, and macular hole formation. The liquefaction process is expedited in diabetic VHs. This project focuses on understanding the molecular changes that lead to liquefaction and the reasons for which this process is accelerated with diabetes. Matrix-assisted laser desorption ionization/mass …

Fostering Compassionate Care For Persons With Alzheimer's Disease In Nursing Facilities., Sam Gilbert Cotton

Electronic Theses and Dissertations

The aim of this dissertation study was to examine the impact of the implementation of a new Compassionate Care (CC) curriculum on the quality of care provided by Certified Nursing Assistants (CNAs) to residents with Alzheimer’s disease (AD). More specifically, this dissertation used Kirkpatrick’s model of evaluation to assess the reactions, learning, and behavior change of the CNAs exposed to the curriculum, and ultimately the impact of the curriculum on the stress levels of residents with AD. To accomplish this, we had two studies that aligned with the Kirkpatrick model of evaluation. For Study #1, the evaluation of the compassionate …