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The Effects Of Gang Membership And Transitions In A Gang On Within-Individual Changes In Offending., Leon Sergio Garduno
The Effects Of Gang Membership And Transitions In A Gang On Within-Individual Changes In Offending., Leon Sergio Garduno
Electronic Theses and Dissertations
Researchers have established that joining a gang exposes individuals to factors and environments that promote and increase antisocial and illegal behaviors, which decrease after leaving the gang (Decker & Van Winkle, 1994; Melde & Esbensen, 2014; Thornberry, Krohn et al., 1993). Scholars, by analyzing qualitative data, bivariate statistics, and by comparing gang members with non-gang members, have found that as individuals join and leave a gang they experience changes in the frequency with which they carry firearms, sell drugs, and engage in property crimes (Bjerregaard & Lizotte, 1995; Hagedorn, 1994; Thornberry et al., 1993). Researchers also have established that within-individuals’ …
Applications Of Nuclear Magnetic Resonance Spectroscopy: From Drug Discovery To Protein Structure And Dynamics., Mark Vincent C. Dela Cerna
Applications Of Nuclear Magnetic Resonance Spectroscopy: From Drug Discovery To Protein Structure And Dynamics., Mark Vincent C. Dela Cerna
Electronic Theses and Dissertations
The versatility of nuclear magnetic resonance (NMR) spectroscopy is apparent when presented with diverse applications to which it can contribute. Here, NMR is used i) as a screening/ validation tool for a drug discovery program targeting the Phosphatase of Regenerating Liver 3 (PRL3), ii) to characterize the conformational heterogeneity of p53 regulator, Murine Double Minute X (MDMX), and iii) to characterize the solution dynamics of guanosine monophosphate kinase (GMPK). Mounting evidence suggesting roles for PRL3 in oncogenesis and metastasis has catapulted it into prominence as a cancer drug target. Yet, despite significant efforts, there are no PRL3 small molecule inhibitors …
Targeting Pathological Changes In The Gut Protects The Cns From Neuropathology., Benjamin Tyler Charpentier
Targeting Pathological Changes In The Gut Protects The Cns From Neuropathology., Benjamin Tyler Charpentier
Electronic Theses and Dissertations
There is growing evidence that the health of the gut microbiome (GM) has an important role on multiple host organ systems. Ethanol-related neuropathologies and Alzheimer’s disease (AD) currently have no effective clinical treatment. Therefore, we developed a novel mouse model of fecal matter transplantation (FMT) utilizing the microbiome from alcoholic hepatitis (AH) patients, characterized by a loss of butyrogenic potential. Minimal neuroinflammation occurred in AH-FMT mice, but significant increases in the endoplasmic reticulum stress response (ERSR) across the majority of neurons in the prefrontal cortex and hippocampus were observed. In the cerebellum, Purkinje cells were specifically affected. Targeting the loss …
Meeting The Mental Health Needs Of College-Aged Young Adults: Evaluating The Value And Impact Of Digital Mental Health Interventions., Sara Atherton Choate
Meeting The Mental Health Needs Of College-Aged Young Adults: Evaluating The Value And Impact Of Digital Mental Health Interventions., Sara Atherton Choate
Electronic Theses and Dissertations
BACKGROUND: The growing prevalence of common mental health problems poses a serious hindrance to young adults, and the majority of those in need of mental health support do not seek professional psychological services. Digital mental health interventions (DMHIs) that allow for self-management of mental health symptoms could provide a useful adjunctiveto traditional one-on-one counseling or therapy and offer a useful prevention tool for students at risk for experiencing mental health crises. This dissertation explored the efficacy of self-guided DMHIs targeting college students, the factors associated with help-seeking in young adults, and the impact of implementing an evidence-based DMHI at a …
The A-Word: Destigmatizing Abortion In American Culture., Kathryn Lafferty Danner
The A-Word: Destigmatizing Abortion In American Culture., Kathryn Lafferty Danner
Electronic Theses and Dissertations
This dissertation uses an interdisciplinary perspective and explores the topic of abortion through legal, medical, philosophical, and cultural perspectives, providing alternative ways to talk about abortion. In some states, especially since the overturning of Roe, abortion has become almost impossible to access, particularly in the South and Midwest. Abortion as a medical procedure is highly stigmatized and although it is a common procedure, it is taboo to discuss in American culture. Exploring how different media work to destigmatize abortion in the United States can lead to a deeper, more nuanced understanding of an overly politicized topic. The introduction is a …
“…You Can't Unknow It, It's A New Reality": A Case Study Exploring A Social Justice Public Health Intervention's Impact On Critical Consciousness Development In Youth., Monique Williams
Electronic Theses and Dissertations
Even though public health purports to be rooted in social justice, it is not clear how social justice frameworks are integrated in public health research and intervention. The discipline focuses on groups/populations on the margins, without integrating the social and political factors that cause marginalization into the intervention. Seeing communities, and individuals, as assets and experts in their own experiences is key to population-level health improvement. Particularly for public health youth intervention, how youth are labeled and engaged in social change is critical to their healthy development. While public health lags in practically applying asset-based approaches to youth intervention, research …
The Influence Of Sponsorship Engagement On Brand Loyalty: An Analysis Of The On-Site And Social Media Activational Communications., Achyut Kulkarni
The Influence Of Sponsorship Engagement On Brand Loyalty: An Analysis Of The On-Site And Social Media Activational Communications., Achyut Kulkarni
Electronic Theses and Dissertations
The purpose of this study was to investigate the influence of sponsorship engagement (enacted via sponsorship activations) on consumers’ responses to sponsors’ activational communications. Specifically, this study aimed at examining if interaction and engagement with their team’s sponsors’ activational communication on-site, as well as on social media, influenced loyalty towards the sponsors. The study utilized service-dominant (S-D) logic as the theoretical framework. The S-D logic perspective recognizes that consumer behavior is centered on the interactive experiences between a consumer and an object, in this case the sponsor, and that a level of consumer interest and/or personal relevance with respect to …
Computer Aided Diagnosis System For Breast Cancer Using Deep Learning., Asma Baccouche
Computer Aided Diagnosis System For Breast Cancer Using Deep Learning., Asma Baccouche
Electronic Theses and Dissertations
The recent rise of big data technology surrounding the electronic systems and developed toolkits gave birth to new promises for Artificial Intelligence (AI). With the continuous use of data-centric systems and machines in our lives, such as social media, surveys, emails, reports, etc., there is no doubt that data has gained the center of attention by scientists and motivated them to provide more decision-making and operational support systems across multiple domains. With the recent breakthroughs in artificial intelligence, the use of machine learning and deep learning models have achieved remarkable advances in computer vision, ecommerce, cybersecurity, and healthcare. Particularly, numerous …
The Person Behind The Team: A Phenomenological Exploration Of The Role Of The Sport Supervisor In Ncaa Division I Intercollegiate Athletics., Ehren R. Green
The Person Behind The Team: A Phenomenological Exploration Of The Role Of The Sport Supervisor In Ncaa Division I Intercollegiate Athletics., Ehren R. Green
Electronic Theses and Dissertations
As organizational connectors, athletic administrators who serve as sport supervisors, are integral to the success of intercollegiate athletic departments. However, little is known about the role of sport supervisor or the relationship between sport supervisors and head coaches. Thus, this study seeks to define and better understand the role of the sport supervisor in intercollegiate athletics and explore the relationship between the sport supervisor and the head coach. Through a descriptive phenomenological approach, 22 participants (11 sport supervisors and 11 head coaches) from NCAA Division I institutions were interviewed. Role theory guided the defining of the role while leader-member exchange …
Rewriting Writing As Transmodal And Translingual: Tranßcribing Japanese., Alex Way
Rewriting Writing As Transmodal And Translingual: Tranßcribing Japanese., Alex Way
Electronic Theses and Dissertations
This dissertation analyzes the use of different scripts in Japanese writing practices to disrupt English-language and Western-centric approaches to multimodal composition. Early chapters establish a brief history of the Japanese writing system (JWS) and explore its functionality. I trace the JWS’s development from borrowed Chinese characters (kanji), which were adapted to the Japanese language through the translation process of kundoku, to the contemporary system which utilizes the supplemental phonetic scripts of hiragana and katakana, in part, to represent Japanese syntax. Building on this historical context, I demonstrate how the use of the Japanese multi-scripts (hiragana, katakana, and kanji) in conventional …
Induction Of Trained Immunity By Particulate Β-Glucan Controls Cancer Metastasis Through The Sphingolipids-Mediated Mitochondrial Fission Pathway., Rejeena Shrestha
Induction Of Trained Immunity By Particulate Β-Glucan Controls Cancer Metastasis Through The Sphingolipids-Mediated Mitochondrial Fission Pathway., Rejeena Shrestha
Electronic Theses and Dissertations
Metastasis is the leading cause of cancer-related deaths and innate immune cells are critical players in the metastatic microenvironment. Here, we explore the implications of harnessing the pre-metastatic niche myeloid cells through induction of trained immunity using a natural compound yeast-derived whole β-glucan particle (WGP). WGP training in macrophages results in an increased responsiveness to not only the conventional secondary stimulus LPS but also specifically to tumor cells and tumor-derived factors. WGP in vivo treatment leads to a trained immunity phenotype in lung interstitial macrophages (IMs). Induction of trained immunity by WGP inhibits tumor metastasis and enhances tumor-free survival in …
Media Portrayal Of Private Prisons And Inmates., Ladye Anna L. Adams
Media Portrayal Of Private Prisons And Inmates., Ladye Anna L. Adams
Electronic Theses and Dissertations
Private prisons have existed in the United States since 1986, but research about prison privatization has been limited. To date, there have been two published studies examining how mainstream media sources frame prison privatization to their audiences. This thesis attempts to address this gap in the literature. Using content analysis, I evaluate how mainstream media frames prison privatization and inmates housed in private prisons. The analysis is conducted in two parts. The first tests if private prison reduction or expansion is the focus of the news story if framed using economic benefits, ethical concerns, or prisoner violence. The second tests …
Taiwanese Indigenous Representation, Rhetoric Of Resistance, And Heteroglossia In Warriors Of The Rainbow: Seediq Bale., John Yu-Choh Chang
Taiwanese Indigenous Representation, Rhetoric Of Resistance, And Heteroglossia In Warriors Of The Rainbow: Seediq Bale., John Yu-Choh Chang
Electronic Theses and Dissertations
This dissertation explores the relationship between Taiwanese indigenous narrative and rhetoric, in textual representations of the Seediq people and the 1930 Musha Incident. It explores how the forced colonization of Taiwanese indigenous people affected their identities and cultural representation, and how multi-voiced forms of narrative, storytelling, and meaning-making have rooted in indigenous oral traditions and rituals that counter colonial representations. Across a range of cultural texts, I identify what I call Taiwanese indigenous rhetoric of resistance (TIRR), drawing on Simon J. Ortiz’s theory of indigenous literature and oral traditions as indigenous-nationalist forms of cultural resistance. In addition, I draw on …
Characterization Of Microbotryum Lychnidis-Dioicae Secreted Effector Proteins That Manipulate Its Host Plant, Silene Latifolia., Ming-Chang Tsai
Characterization Of Microbotryum Lychnidis-Dioicae Secreted Effector Proteins That Manipulate Its Host Plant, Silene Latifolia., Ming-Chang Tsai
Electronic Theses and Dissertations
The smut fungal species Microbotryum lychnidis-dioicae is an obligate phytopathogen colonizing the plant host, Silene latifolia. A significant feature of M. lychnidis-dioicae infection is that the fungus can replace pollen on the anthers of susceptible host plants with fungal teliospores, thus earning the fungus the name: anther smut disease of flowers. The fungus synthesizes and secretes effector proteins into the cells of the plant host during infection, and the protein-protein interactions may interfere with and modify metabolism, plant development, and gene expression of the host to allow fungal colonization. Two potential fungal effector proteins, MVLG_06175 and MVLG_05122, were identified …
Cultivating The Human Narrative: On Nietzsche, Science Fiction, And The Aesthetics Of Life., Derek Carpenter
Cultivating The Human Narrative: On Nietzsche, Science Fiction, And The Aesthetics Of Life., Derek Carpenter
Electronic Theses and Dissertations
In this dissertation, I will argue that there is a specific model of morality which can account for the intuition about moral features that we take to be intrinsic to the human type. This model of morality is that of Virtue Ethics, but not a conventional kind of Virtue Ethics. Instead, I will argue that the moral philosophy of Friedrich Nietzsche presents a model of cultivating narrative types that we take to be grounded in the kinds of beings we are, without resorting to any problematic metaphysical systems. This will require that I defend a novel interpretation of Nietzsche’s ethics …
The Ties That Bind: Creole Networks And Reform In New Granada During The Age Of Revolution, 1780-1811, Philip John Baltuskonis
The Ties That Bind: Creole Networks And Reform In New Granada During The Age Of Revolution, 1780-1811, Philip John Baltuskonis
Electronic Theses and Dissertations
At the beginning of the nineteenth century, Spanish Americans were immersed in a practical Enlightenment that aimed to improve society during the Age of Revolution (1780-1850). In the city of Santafé de Bogotá, elites comprised of Spaniards and creoles (Spaniards born in the Americas) joined in scientific expeditions, higher education, creating newspapers, and proposing economic and educational reforms that all promised to bring prosperity to the Viceroyalty of New Granada (present-day Colombia, Venezuela, Ecuador, and Panama). Rather than a source of major confrontation, elites’ activities aligned with the Spanish Crown’s interest in turning its American kingdoms into centers of wealth. …
Seeing Queer Joy In Mississippi: Pride Parades In Tupelo, Starkville, And Oxford, Ellie Campbell
Seeing Queer Joy In Mississippi: Pride Parades In Tupelo, Starkville, And Oxford, Ellie Campbell
Electronic Theses and Dissertations
In May of 2016, Oxford, Mississippi, held its first LGBTQ+ Pride parade in recent memory. That first Oxford Pride was part of a wave of LGBTQ+ celebrations that began in the state in 2015 and 2016 and continue to the present day. Though the pandemic forced many to cancel or go online, communities across Mississippi have continued to organize Pride parades and other celebrations of LGBTQ+ identities since 2015, a marked contrast from earlier periods. In a state often depicted as actively hostile to queer people, these Pride events make queer southern communities visible in new ways, while also revealing …
Social Distance, Stigma, And Help-Seeking: A Comparison Of Lay And Professional Conceptualizations Of Autism In The Southern Us, Christian Shannon Courson
Social Distance, Stigma, And Help-Seeking: A Comparison Of Lay And Professional Conceptualizations Of Autism In The Southern Us, Christian Shannon Courson
Electronic Theses and Dissertations
Understanding stigma, help-seeking and barriers to treatment for persons with Autism Spectrum Disorder (ASD) is essential for informing interventions toward increased relevance and utility. An array of sociocultural and individual factors can influence lay beliefs and behavioral responses to ASD, including stigma and social distancing (i.e., preference for distance from autistic individuals). It is important to consider the Explanatory Models of ASD among helping professionals (e.g., health care, education) as they are likely touchstones along the help-seeking pathway for children with ASD. The purpose of this study was twofold: 1) to explore factors in the southern United States associated with …
Perceptions Of Sexual Refusals: Not So Black And White, Lavina Ying Ho
Perceptions Of Sexual Refusals: Not So Black And White, Lavina Ying Ho
Electronic Theses and Dissertations
Sexual assault is an issue affecting approximately 1 in 5 women. Compared to White women, Black women report higher rates of lifetime rape, are at risk of developing physical/mental health issues post-assault (e.g., depression, posttraumatic stress disorder, and substance abuse), and are less likely to engage in help-seeking after sexual victimization. Research reveals the manner in which a woman refuses a sexual advance can influence a man’s perceptions of the genuineness of her refusal. Sexual refusals that are explicit (e.g., not wanting to have sex due to religious beliefs) are identified more quickly as violating a woman’s boundaries than sexual …
Fabrication Of Porous Extended-Release Tablets Using Dual Nozzle Fused Deposition Modeling 3d Printing Techniques, Sung-Chi Lee
Fabrication Of Porous Extended-Release Tablets Using Dual Nozzle Fused Deposition Modeling 3d Printing Techniques, Sung-Chi Lee
Electronic Theses and Dissertations
The aim of this study was to fabricate shell-core porous tablet formulations by fused deposition modeling dual nozzle three-dimensional printing coupled with hot-melt extrusion techniques. Acetaminophen was selected as the model drug for this study owing to its pH-independent property. The 3-point bend test and the stiffness test were performed to investigate the printability of filaments. The stiffness constant, k, was calculated to represent the printability by fitting the breaking distances and stress data into Hooke’s law. The formulation 1 (F1) and formulation 2 (F2) filaments were printed successfully by demonstrating the preferred hardness with 16.74±3.55 and 14.72±2.20 respectively in …
Mississippi Modernism: The River Valley And Race In American Culture, 1892-1945, William C. Palmer
Mississippi Modernism: The River Valley And Race In American Culture, 1892-1945, William C. Palmer
Electronic Theses and Dissertations
Mississippi Modernism looks to the Mississippi River Valley of the last decade of the nineteenth century and the first few decades of the twentieth century to analyze the ways individuals expressed and determined their experience in the changing world. By engaging with theories of modernity from Marshall Berman and the Black modernism of Houston A. Baker, Jr. this work proposes the Mississippi watershed as a region where individuals indulge in the processes of modernism remaking the environments, both urban and rural, surrounding them. By thinking about the “dry†and “wet†valleys envisioned by European settlers as Christopher Morris terms it, …
Teaching In A Remediation Nation: Exploring Journalism And Mass Communication Faculty Perceptions Of Their Professional Practice, Andrew Mark Abernathy
Teaching In A Remediation Nation: Exploring Journalism And Mass Communication Faculty Perceptions Of Their Professional Practice, Andrew Mark Abernathy
Electronic Theses and Dissertations
Research shows many new college students may be remedial in English language arts or mathematics (Jaggers & Bickerstaff, 2018). For faculty in journalism and mass communication (JMC) fields, teaching struggling student writers can be especially challenging as these students may not have the fundamental knowledge to build applied writing skills upon. Thus, this lack of readiness for collegiate writing poses challenges to not only these students’ academic success, but also their transition into media professions. Embedded remediation—an alternative to traditional, prerequisite remediation—is one strategy that JMC faculty can use to support struggling student writers. This dissertation explores how JMC faculty …
Transformation From Orality To Literacy: Studying The Effect Of Orality In Al-Jahiz’S Al-Bayan Wa Al-Tabyeen., Faiz Alasmari
Transformation From Orality To Literacy: Studying The Effect Of Orality In Al-Jahiz’S Al-Bayan Wa Al-Tabyeen., Faiz Alasmari
Electronic Theses and Dissertations
The transition from orality to literacy is the focus of this dissertation. Studying orality and literacy in Western Academic scholarship focuses on the transitional phase (transition from orality to literacy) of the Western transitional. This project widens the focus of the transitional phase and analyzes the transitional phase of the old traditional Arabic culture. The dissertation analyzes both oral and transitional phases of the old Arabic culture. It studies the unique characteristics of these two phases (oral and transitional). Isnad was the main feature of the Arabic transitional phase. Isnad is a chain of narrators who convey sayings. Every narrator …
Examining Overrepresentation In Special Education Amongst African Americans Diagnosed With Emotional Disturbance In The State Of Pennsylvania, Krisa Franzetta
Examining Overrepresentation In Special Education Amongst African Americans Diagnosed With Emotional Disturbance In The State Of Pennsylvania, Krisa Franzetta
Electronic Theses and Dissertations
This study examines the disproportionality in special education, regarding African American students being overrepresented, specifically under the disability category of Emotional Disturbance (ED) within the state of Pennsylvania. Demographic information was collected with the use of secondary data provided by the Pennsylvania Department of Education, using 648 educational programs across 29 intermediate units. Data were analyzed with statistical representation of percentages as related to risk composition and the E-Formula. The results yielded an average risk of African American students being two times more likely to be diagnosed with ED than their White peers. Additional results from the calculation of the …
Genomic Analysis And Metabolic Potential Of Myxobacteria, Hanan Albataineh
Genomic Analysis And Metabolic Potential Of Myxobacteria, Hanan Albataineh
Electronic Theses and Dissertations
Myxobacteria are known for their large genomes that bestow them with a distinct lifestyle that is characterized by fruiting body formation, gliding motility, social interactions, predation, and secondary metabolite production. The powerful combination of whole-genome sequencing and bioinformatics-driven analysis of sequence data has delivered unexpected insights into myxobacterial microbial communities. We applied these two approaches to investigate the chemical space and biosynthetic potential of myxobacteria. Mining different myxobacterial genomes for biosynthetic gene clusters led us to the discovery of a cryptic acyl-homoserine lactone (AHL) synthase encoded in the genome of the myxobacterium Archangium gephyra. Bioinformatic analysis of this AHL synthase …
Chasing The Light, Nadia Alexis
Chasing The Light, Nadia Alexis
Electronic Theses and Dissertations
Chasing the Light is a young adult novel-in-verse is a 16-year-old Haitian American teen photographer and survivor of dating violence who is a lover of myth and folklore, who is good at keeping secrets, and who is hungry for freedom. Her parents want her to follow the traditional path of going to college and pursuing a well-paying career like becoming a lawyer or a doctor. She wants to be free to uncover truths about her newly single self and to make her mark as a young artist aspiring to go to college to study photography so she could become a …
Bridging Souths: Interdisciplinarity And Knowledge Production In Southern Studies, Matthew David Streets
Bridging Souths: Interdisciplinarity And Knowledge Production In Southern Studies, Matthew David Streets
Electronic Theses and Dissertations
This thesis examines the viability of southern studies, a regional studies project on the study of the U.S. South, as an academic field of study and institutionalized site of multi-, inter-, and transdisciplinary knowledge production. Southern studies has undergone numerous turns and paradigm shifts since its institutionalization in the 1970s. These ontological, epistemological, and methodological developments have reoriented the objectives of interdisciplinary knowledge production. Despite the present permeability of disciplinary boundaries, the institutional structure and its racial, capitalist, and disciplinary hierarchies hinder communication and collaboration across disciplines and fields and between the “ivory tower†and “real world.†Understanding the impact …
Our Bodies, Our Stories: Mental And Physical Self Connection As A Protective Factor In Sexual And Gender Minorities, Emerson A. Todd
Our Bodies, Our Stories: Mental And Physical Self Connection As A Protective Factor In Sexual And Gender Minorities, Emerson A. Todd
Electronic Theses and Dissertations
The mind and body connection has been actively examined in neuroscience and developmental psychology backgrounds. Sociological theorists posit ways that individuals develop a sense of self through mind, body, and the social world. While research on the connection between the mind and body in disabled and aging populations is common, less is known of the everyday impact of these connections for other minority populations. The present study uses mixed-methods research to explore the relationship between mind and body and the impacts on internal and social life. The quantitative aspect of the study found significant relationships between physical and mental health …
Educator Perceptions Of The Working Environment In Tennessee Elementary Schools That Actively Employ Positive Behavior Supports And Restorative Practices, Scott Thomas Lamie
Educator Perceptions Of The Working Environment In Tennessee Elementary Schools That Actively Employ Positive Behavior Supports And Restorative Practices, Scott Thomas Lamie
Electronic Theses and Dissertations
This phenomenological study captured the experiences of elementary educators with the purpose of gathering their perceptions of the use of restorative practices and positive behavior supports in their schools with a particular focus on how these programs influenced school climate, their professional efficacy, and their job satisfaction. Results of interviews lead to the emergence of seven major themes, which were the importance of understanding the underlying causes of student behavior, change, common practices of positive behavior supports and restorative practices, benefits for students, benefits for educators, struggles with implementation, and suggestions for implementation. These findings led to the identification of …
Tobacco-Derived Aldehydes, Platelets, And Thrombogenicity: Role Of Transient Receptor Potential Ankyrin-1., Andre D. Richardson
Tobacco-Derived Aldehydes, Platelets, And Thrombogenicity: Role Of Transient Receptor Potential Ankyrin-1., Andre D. Richardson
Electronic Theses and Dissertations
Cardiovascular disease (CVD) remains the world’s leading cause of morbidity and mortality. Conventional smoking of tobacco cigarettes is the number one risk factor for onset of CVD. Active cigarette users as well as those individuals who are exposed to second-hand cigarette smoke are at increased risk of CVD. Studies have shown that conventional smoking significantly increases a user’s risk of thrombosis, atherosclerosis, peripheral arterial disease, and coronary artery disease. Any of these diseases may trigger myocardial infarctions, stroke, or hypertension that may lead to cardiovascular morbidity and mortality. New and emerging electronic nicotine delivery systems (ENDS), such as electronic cigarettes …