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A Phenomenological Study Of Science Teachers’ Lived Experience: Pedagogical Judgment During The Covid-19 Pandemic, Amy Vo

Electronic Theses and Dissertations

At the beginning of the COVID-19 pandemic, in March of 2020, education in the United States changed dramatically. Science teachers began to look at the implementation of ambitious and equitable science teaching practices differently. Employing the hermeneutic phenomenological framework, the purpose of this study was to investigate the lived experience of science teachers, specifically looking at their pedagogical judgment related to ambitious and equitable science teaching. Semi-structured interviews, artifacts and surveys were used to develop a rich description of the phenomenon. Data analysis of the science teachers’ narratives, Qualtrics surveys, and lesson plans illuminated six essential themes common to all …

Mechanistic Insights Into Mftr-Dependent Regulation Of The Redox Cofactor Mycofactocin, Aigera Mendauletova

Electronic Theses and Dissertations

Organic redox cofactors are essential for life. While classic flavins and nicotinamides are widely distributed across all domains of life, nature has also evolved niche cofactors in subsets of life domains. For example, in Actinobacteria, coenzyme F420 is commonly used in place of flavin mononucleotide in enzymes associated with carbon fixation and oxidation of secondary alcohols. The importance of niche cofactors has long been recognized however, detailed understanding about their biosynthesis and physiological uses has been lagging. One class of niche cofactors is derived from ribosomally synthesized and posttranslationally modified peptides (RiPPs). To achieve their mature form, the genetically …

Plant Community Response To Control Of A Dominant Invader At Multiple Scales, Alexander R. B. Goetz

Electronic Theses and Dissertations

Control of invasive Tamarix spp. in riparian systems has long been a priority for management in western North America, but questions remain regarding the response of the broader plant community to different treatments. Here we summarize a series of approaches at different scales to quantify the effects of Tamarix control on characteristics of this ecosystem, including provisioning of wildlife habitat. In the first chapter we analyzed findings of the last 20 years using meta-analysis and found that although treatment has been successful in reducing Tamarix and promoting native vegetation to some extent, most literature reports very small effect sizes and …

Developing Red Fluorescent Zn2+ Sensors And Characterizing Zn2+ Homeostasis In Mucolipidosis Type Iv Disease, Anna M. Dischler

Electronic Theses and Dissertations

Zinc (Zn²⁺) is a divalent, redox-inert metal that plays a vital role in many cellular processes either by acting as a catalytic cofactor or a labile signaling molecule in the cytoplasm. Cytosolic Zn²⁺ levels are tightly regulated to stay within a narrow window of concentrations, but fluctuations in Zn²⁺ signals have been detected in a variety of cells. We developed a genetically encoded, single red fluorescent protein (RFP) based Zn²⁺ sensor, RZnP1, that can be used alongside green-wavelength sensors for the simultaneous detection of different signaling molecules within the same cells or among different subcellular …

Virtual Reality Influence On Moral Reasoning Through Compassion, Dennis W. Dunivan

Electronic Theses and Dissertations

This study investigates quantifiable links between virtual reality, moral reasoning, and compassion, contributing to the development of improved pedagogy for moral leadership development through experiential learning. It is the first empirical study to determine how specific virtual reality experiences potentially influence moral reasoning as measured by the DIT-2 (Rest et al., 1999), as well as the possible mediation effects of compassion on this relationship as measured by the Compassion Scale (Pommier et al., 2019). Although pedagogical implications are discussed, including the integration of virtual reality experiences into curriculum, the boundaries of this study are controlled to measure the direct influence …

Guaranteed Income As A Structural Social Work Response To Homelessness In The United States, Katherine Hoops Calhoun

Electronic Theses and Dissertations

The number of projects exploring guaranteed income, or unconditional direct cash transfers, in the United States has exploded in recent years (Mayors for a Guaranteed Income, 2022a). Between June 2021 and June 2022, the number of city mayors engaged with the group Mayors for Guaranteed Income grew from 11 to 82 (Mayors for a Guaranteed Income, 2022b) and as of Winter 2023, there were over 90 guaranteed income demonstrations and projects in the United States (Guaranteed Income Community of Practice, 2023). Guaranteed income refers to direct cash transfers, often to targeted populations, that are unconditional, consistent, predictable, and flexible (Castro …

Black Quarterback, White Masks: A Critical Analysis Of The Nfl Anthem Protests, Cody Walizer

Electronic Theses and Dissertations

The NFL anthem protests were and are an important cultural moment and social movement. The widespread emulation of the protest, and the adoption of the kneel as a symbol of unity, reverence, and silent objection demonstrates the protests’ continued relevance. This dissertation critically analyzes Colin Kaepernick’s protest through the lens of racial rhetorical criticism (Flores, 2016) and Fanonian communication studies (Towns, 2020). Through the case studies of David Brooks, Lee Siegel, and Colin Fleming, and their New York Times opinion pieces on Kaepernick from 2016-17, this study argues that the common discourses surrounding the protest exist within the strategic rhetoric …

Post-Translational Modification Of Proteins Via Ambient Air Pollutants And Endogenous Reactive Species, Rachel Lauren Davey

Electronic Theses and Dissertations

Proteins can react with reactive oxygen species (ROS) and reactive nitrogen species (RNS) to form post-translational modifications (PTMs), which can affect protein structure and function. The formation of 3-nitrotyrosine (NTyr) and dityrosine (DiTyr) upon reaction of proteins with ROS/RNS are two common PTMs studied due to their stability and irreversibility, as well as their ability to enhance the allergenicity of pollen allergens upon formation. Many common techniques used to study the formation of these PTMs can reliably detect the PTMs but can only provide semi-quantitative information due to many assumptions and limitations. In Chapter 2 we present an analysis of …

Universal Basic Income (Ubi): A Cure-All Or Band-Aid?, Madison Beckner

Electronic Theses and Dissertations

With the triple crisis of capitalism looming and, in the U.S., a poorly performing welfare state, Universal Basic Income (UBI) has returned to popular attention. To assess whether this is warranted and, more importantly, to provide answer on the extent to which a UBI can or should be considered a cure-all, this work, first, examines the historical development of UBI proposals including those stemming from European Social Democrats and Libertarians. Next, pilot programs at the local, state, and national level are critically examined for their methodologies and empirical results. Turning, then, to theory on de-commodification, unpaid labor, and the equality-jobs …

Islamic Studies Teachers' Perspectives Of Applying Technology In Saudi Arabia Elementary Schools, Amal Abdulmohsen Alsaif

Electronic Theses and Dissertations

In recent years, the use of technology in education has been on the rise around the world, and Saudi Arabia is no exception. The integration of technology in Saudi education has the potential to enhance the quality of education, increase access to education, and provide students with the skills they need to succeed in a rapidly changing world. It also has the potential to facilitate collaboration between students and teachers, both within and outside the classroom, and to promote lifelong learning.

The purpose of this qualitative study is to investigate Islamic Studies teachers' perceptions of using technology in their classrooms …

Ethics In Kakadu (1988): Finding Djilile’S “True Tracks”, Natasia T. Boyko

Electronic Theses and Dissertations

Tasmanian-born Peter Sculthorpe (1929 – 2014) was one of Australia’s most iconic modernist classical composers of the twentieth century. Kakadu (1988) seems to have sparked the most controversy of Sculthorpe’s works and has become one of his most well-known pieces. In the program notes provided in the score’s foreword, Sculthorpe asserts that “the melodic material in Kakadu, as in much of my recent music, was suggested by the contours and rhythms of Aboriginal chant.” Sculthorpe attributed this melodic material to the Arnem Land chant, Djilile. Consequently, Sculthorpe has been criticized for extracting Djilile from its authentic context as …

3 Essays On Protests, Repression, And Signaling, Dogus Aktan

Electronic Theses and Dissertations

This dissertation focuses on conceptual development across multiple questions of political contention, with a focus on informational processes. In the first paper, I examine the interaction of informational and disruptive effects of protests with a formal model. The model shows that repression can have a screening purpose. Governments use coercion to set the terms of contention so that they only have to accommodate sufficiently aggrieved and salient groups, while filtering out the rest. The model also demonstrates that decreased cost of mobilization makes repression indirectly cheaper for governments, leading to more repression. In the second paper, I examine why governments …

The Not-So-Silent Period: Testimonios Of Recently Arrived Latinx Students, Teri M. Hutchinson

Electronic Theses and Dissertations

The purpose of this study was to explore and amplify the experiences of recently arrived Latinx¹ students as interpreted through their testimonios in educational borderlands. Through increasingly xenophobic discourses around immigrants and their children (Pérez Huber, 2015), U.S. public schools have become entrenched borderland spaces wherein the humanity of recently arrived students is voided through silencing them with labels of linguistic deficiency and cramming them into one-size-fits-all educational programming (Fine et al., 2007; Flores & Rosa, 2015). There is demand for research that explores the experiences of these children, especially in light of their continued marginalization through neoliberal programming …

Three-Dimensional Extrusion Based Bioprinting Of Metronidazole Immediate Release Tablets; Impact Of Processing Parameters And In-Vitro Evaluation, Atharva Bhatkande

Electronic Theses and Dissertations

The purpose of the current study was to evaluate the applicability of a 3-Dimensional extrusion-based bioprinter in developing a 3D-printed tablet as a single-step process. Metronidazole was used as a model drug, and Eudragit® EPO as a taste-masking polymer for formulating taste-masked tablets. Processing parameters were optimized for the nozzle's printing speed, a printhead's heating temperature, and pressure. Oval-shaped tablets were printed with a rectilinear printing pattern of 30% and 100% infill. 3D printed tablets were characterized by Differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), and Scanning electron microscopy (SEM). The F9, F10, and F11 formulations showed desired printability, …

Fabrication And Characterization Of Amlodipine Besylate Based Sub-Cutaneous Implants: Fabricated With The Help Of Hot Melt Extrusion, Kshitij Chitnis

Electronic Theses and Dissertations

Hypertension (HTN) can lead to heart attack, cardiac arrest, or coronary heart disease, and eventually death without proper treatment. Amlodipine Besylate (AMB) was approved by, US Food and Drug Administration in 1987, as a monotherapy for the management of HTN. AMB is commercially available in tablet (2.5, 5, and 10 mg) and solution (1mg/mL) dosage forms. However, adherence to the properly prescribed dosage form is critical and difficult for patients with chronic diseases such as HTN to prevent illness progression and death. The objective of the study was to develop AMB-loaded subcutaneous implants to reduce the frequency of administration, thus, …

Formulation And Evaluation Of Prochlorperazine Maleate Sustained Release Mucoadhesive Buccal Films Using Hot Melt Extrusion, Umesh Chandra Chowdary Devineni

Electronic Theses and Dissertations

Many patients find it difficult to swallow tablets or hard gelatin capsules and fail to comply with prescriptions, resulting in a high incidence of noncompliance and ineffective treatment. Well, in recent years, buccal drug delivery has gained significant attention as a potential alternative to traditional drug delivery systems. Prochlorperazine Maleate is a widely used antiemetic drug for treating nausea and vomiting caused by various medical conditions. However, its oral administration is associated with poor bioavailability and inconsistent therapeutic effects. To overcome these limitations this study aims to develop sustained release mucoadhesive buccal films of Prochlorperazine Maleate using the Hot Melt …

Developing Biomolecular Hydrogen Evolution Catalysts Using De Novo Designed Self-Assembling Metallopeptides And Metallothionein Scaffolds, Sreya Malayam Parambath

Electronic Theses and Dissertations

The imbalance between the consumption and production of energy is one of the global issues of the century. At present, the most used source of energy is fossil fuel. Even though these are non-renewable source of energy that depletes over time, burning fossil fuel can cause several environmental problems, which include significant issues such as global warming; ocean acidification; and the issues such as water pollution from coal mining. Thus, it is important to find a renewable and environmentally friendly source of energy to meet the increasing demands of the rapidly growing global population. Hydrogen is considered a secure and …

Photophysical Characterization Of Small Organic Molecules Via Time-Resolved And Steady-State Spectroscopic Techniques, Cameron Luke Smith

Electronic Theses and Dissertations

This dissertation describes in detail the photophysical characterization of novel organic dyes in the infrared region for bioimaging purposes in a rapidly evolving field which originates from the need for more efficient and bright systems that are capable of replacing current commercial options and functioning in biologically relevant media. Biological tissue, whether it be muscle, adipose, or epithelium, has a higher scattering efficiency, greater light attenuation, and stronger autofluorescence at shorter wavelengths, thus limiting the biological window to longer wavelengths. The goal of this dissertation was the comparison of novel organic dyes for commercial development as bioimaging dye candidates with …

Free Speech And Students' Rights In Mississippi Public Schools: Exploring Off-Campus Speech, Diala Husni Chaney

Electronic Theses and Dissertations

This case study uses qualitative interviews with building-level principals in Mississippi public high schools along with document analysis to construct standardized policy language for Mississippi School Districts to adopt in order to aid administrators when handling issues involving student off-campus speech. This study rests upon the idea that free speech, and what constitutes free speech, has been and always will be a problem within society, especially with regard to speech used within public schools.

The consensus among researchers is certain types of speech are protected by the First Amendment, while other types of speech are not. By further delving into …

Project Grit: An Applied Research Study Conducted In An Alternative School Program To Promote Alternative Behaviors To Violence, James Ray Howington

Electronic Theses and Dissertations

Students in the Anniston School District are placed in the alternative setting (i.e., the Avery Alternative Center) for fighting and violence more than any other disciplinary infraction. The disproportionality of students of color and minority groups enrolled in the alternative setting for fighting is also alarming. Why is this happening? Why does student conflict often end in physical aggression and violence, especially disputes involving minorities? What can stop the violence? Stakeholders in the Avery Alternative Center created Project GRIT to help answer these questions by incorporating research-based practices and interventions designed to strengthen conflict resolution skills in participants and support …

Harness Therapeutic Potential Of Immune Responses: Molecular Characterization And Targeted Delivery, Nan Ji

Electronic Theses and Dissertations

The immune system plays a crucial role in protecting the body from harmful pathogens and cancer cells and maintaining tissue homeostasis. Immunotherapy has shown significant potential in treating various diseases by harnessing the therapeutic potential of immune responses through the targeting of different immune cells, receptors, and signaling pathways. This dissertation investigated two immune modulators for their immune-enhancing potential.In the first chapter, the components of innate immunity are introduced. In the second chapter, Immulina, a commercially available extract of Arthrospira platensis enriched with Braun-type proteins, was studied for its immunostimulatory effect in mouse bone marrow-derived dendritic cells and macrophages. The …

Sustained And Improved Ophthalmic Formulations Of Gatifloxacin For Better Therapeutic Outcomes During Topical Ocular Applications, Poorva Hemant Joshi

Electronic Theses and Dissertations

Gatifloxacin (GTX) is a broad-spectrum 4th generation antimicrobial fluroquinolone used in the treatment of ocular infections such as conjunctivitis, keratitis and keratoconjuctivitis. GTX (as a sesquihydrate) is commercially available as aqueous eyedrops for the treatment of bacterial conjunctivitis (BC) which requires frequent administration due to low residence time on the conjunctival surface. The eye is a highly specialized photoreceptive organ, which is protected by a continuous tear flow containing antibacterial components. However, inflammation or scarring of the eye may be difficult to resolve once having occurred. Furthermore, initial infections if ignored are likely to invade the inner portions of the …

Exploration Of Student Success Programs For Freshmen Students On Academic Warning/Academic Probation At The University Of Mississippi, Jeremy Roberts

Electronic Theses and Dissertations

Nearly ten percent of the first-year class at the University of Mississippi go on Academic Warning or Academic Probation each semester after their first-full semester at the University. During this time, the student's GPA is below a 2.0, which requires them to take the EDHE 101: Academic Skills for College course, if they plan to return to the University that following Spring or Fall semester (depending on which was their first-full semester). Academic Support Programs, under the Center for Student Success and First-Year Experience oversees this course and several other programs to assist students as they look to return to …

Formulation And Development Of Curcumin Implants For Treatment Of Colorectal Cancer: Application Of Hme And 3d Printing, Neha Rajendra Sali

Electronic Theses and Dissertations

Targeted drug delivery for preventing colorectal cancer (CRC) reoccurrence after surgery can be one of the potent tumor reduction methods among other therapies, such as chemotherapy, ablation, embolization, and radiation therapy. Curcumin has been reported to target the growth factors in carcinoma cells and thereby reducing the proliferation and accelerating the apoptosis of the cancerous cells. Due to its poor bioavailability, it has several limitations for its use in anti-cancer therapy. Piperine has increased the solubility and bioavailability of curcumin and acts synergistically to suppress cancer cell growth. The current study intended to develop novel curcumin implants by coupling hot …

Lipid Based Ophthalmic Nanoformulations For Ciprofloxacin, Moxifloxacin, And Cannabidiol, Ahmed Adel Ali Youssef

Electronic Theses and Dissertations

Ocular drug delivery faces many challenges due to the unique anatomy and physiology of the human eye. The development of ocular drug delivery systems is subjected to a gradual shift from an empirical to a rational base due to a better understanding of the ocular barriers that control drug disposition in the eyeball as well as new approaches in clinical testing. Most of the topically applied actives are lipophilic with low aqueous solubility, and the ocular delivery of these drugs is posing a challenging task. Lipid-based drug delivery systems are well reported to improve solubility and enhance both bioavailability and …

Novel Delivery Systems Of Curcumin And Resveratrol, Mohamed Salem Elfaruk

Electronic Theses and Dissertations

No abstract provided.

Electrospun Recycled Polyethylene Terephthalate Microfibers As An Asphalt Mix Additive, Debbrata Datta

Electronic Theses and Dissertations

In recent decades, the use of different types of fibers in asphalt has become increasingly popular. Fibers are used in an asphalt mix to improve its durability and resistance against distresses such as rutting and cracking due to repetitive vehicle loading at high temperatures, and low-temperature contraction. Consequently, accurate rheological and performance characterization of asphalt binders and mixes containing fibers is of vital importance. With increased concerns over the environmental disruptions as a result of disposing end-of-life plastics in landfills and the need for improving sustainability of the construction materials, incorporating plastic in construction materials has always been an important …

Identifying Optimum Germination Temperatures And Analysis Weights In Seed Testing For Stiff Goldenrod (Solidago Rigida) And River Bulrush (Bolboschoenus Fluviatilis), Rachel Geary

Electronic Theses and Dissertations

Federal and state seed laws require seed lots offered for sale to be tested and labeled with the appropriate information before they can be sold. Those tests are conducted in seed testing labs all around the world. In the United States, accredited seed testing labs follow the Association of Official Seed Analysts (AOSA) Rules for Testing Seeds to provide information for labeling. The rules lack instructions for weights and germination for many native species. Stiff goldenrod (Solidago rigida) and river bulrush (Bolboschoenus fluviatilis) are two species that lack any information required for testing. When seed testing labs use correct weights …

Characterization Of Parp1-Dependent Poly-Adp-Ribosylation Of Sprtn, Quincee Simonson

Electronic Theses and Dissertations

DNA-protein crosslinks (DPCs) are a type of DNA lesion that form when proteins become covalently linked to DNA. It is estimated that replicating cells experience approximately 6,000 DPCs per day per genome during exponential growth (Ruggiano & Ramadan, 2021). If left unrepaired, DPCs can be lethal to cells. For this reason, cells have evolved multiple pathways to repair or bypass DPCs to survive. One such pathway involves SPRTN, a nuclear metalloprotease that plays a key role in the repair of DPCs through direct proteolysis (Lopez-Mosqueda et al., 2016; Vaz et al., 2016). Once SPRTN degrades the bulky protein component of …

Seroprevalence Of Sars-Cov-2 Antibodies Among Rural Healthcare Workers, Jordan Neises

Electronic Theses and Dissertations

The objective of this longitudinal cohort study was to determine the seroprevalence of antibodies to severe acute respiratory syndrome coronavirus-2 (SARSCoV- 2) in healthcare workers employed at healthcare clinics in three rural counties in eastern South Dakota and western Minnesota from May 13, 2020 through December 22, 2020. Three blood draws were performed at five clinical sites and tested for the presence of antibodies against the SARS-CoV-2 virus. Serum samples were tested for the presence of antibodies using a fluorescent microsphere immunoassay (FMIA), neutralization of SARS-CoV-2 Spike-pseudotyped particles (SARS-CoV-2pp) assay, and serum virus neutralization (SVN) assay. The seroprevalence was determined …