Digital Commons Network^™

Development Of Patient-Centric And Various Drug Delivery Systems Utilizing Hot-Melt Extrusion And 3d Printing Techniques., Sooyeon Chung

Electronic Theses and Dissertations

Assuring the quality of medicines is essential and required by pharmaceutical industry. Thus, transition from batch processing of pharmaceuticals to continuous processing is highly encouraged by regulatory bodies nowadays. The hot-melt extrusion technology is very promising technology tool for continuous production and possesses several distinct advantages compared to the conventional practices; it can provide solvent-free process for manufacturing films and granulations, which decreases the risks of compendial issue and health concerns relevant to residual solvents. Also, it has been widely used for acquiring amorphous solid dispersion state, which is an essential technique for enhancing the solubility of poorly-soluble drugs. Furthermore, …

Framed By Education: Labeling, Stigma, And The Behavioral Pathways Of Alternative School Students, Abigail Dempsey

Electronic Theses and Dissertations

Alternative education has emerged as a critical part of the education system, addressing the needs of students who face academic, behavioral, or personal challenges. However, concerns persist about their long-term effectiveness and the stigma associated with alternative school placements. This study examines how stigma tied to alternative school placements impacts delinquency outcomes among adolescents, utilizing labeling theory as a conceptual framework. Drawing on longitudinal data from the Pathways to Desistance dataset, this research explores the relationships between school placement, self-perception of success, and delinquent behaviors. It also serves to investigate whether labeling of an alternative school placement creates a self-fulfilling …

Resilience Imagined In The Mississippi Delta: Exploring Housing, Education, And Community Adaptation In Mississippi’S Internal Colonies, Semonti Jannat

Electronic Theses and Dissertations

This study examines the impact of housing insecurity on educational attainment and community resilience in Cartersville, Mississippi, a historically marginalized community in the Mississippi Delta. Utilizing a qualitative research design, the study draws from in-depth interviews with eleven primary caregivers, revealing the multifaceted ways in which inadequate housing conditions affect children’s learning environments, mental health, and academic performance. The findings indicate that housing instability, manifested through overcrowding, poor infrastructure, and high financial burdens, significantly disrupts students’ educational experiences, contributing to absenteeism, limited academic focus, and stress-induced underperformance.

While the study highlights the persistent socioeconomic challenges linked to the enduring legacies …

Mental Health Literacy: What’S The Value Of Youth Engagement In Intervention Development?, Teresa Johnson

Electronic Theses and Dissertations

Background: One in five youth experience a mental health challenge each year (CDC, 2021). Mental Health Literacy (MHL) is vital for addressing this crisis as it involves the knowledge, attitudes, and skills necessary to promote mental well-being, understand mental health conditions, and seek appropriate help. MHL interventions for adolescents have been developed; however, recent reviews indicate research is needed in school settings with community input. Youth Participatory Action Research (YPAR) places youth as co-researchers in intervention development. This methodology aligns with Bartholomew’s Intervention Mapping (IM) framework, which ensures interventions are theoretically grounded. Utilizing these two frameworks, this study aimed to …

Salinity Tolerance Of Bighead Carp And Its Implications For Dispersal In The Lake Pontchartrain Ecosystem, Alan Katzenmeyer

Electronic Theses and Dissertations

The introduction of invasive bighead carp (Hypophthalmichthys nobilis) into the Pearl and Pascagoula River systems via the Bonnet Carré Spillway during flood control operations poses a significant threat to these unique ecosystems. This dissertation's experiments investigated the role of salinity in limiting bighead carp dispersal, demonstrating that brackish waters do not necessarily restrict their range as previously assumed. While bighead carp exhibited no significant impairment in swimming performance in salinities at or below 5 ppt, acute and chronic exposure to salinities at 15 ppt proved lethal within 50 hours, representing a critical salinity threshold. Despite mortality at elevated salinities, the …

Motivating Students To Read, Lashonda Renee' Johnson

Electronic Theses and Dissertations

This applied research study was conducted to motivate third-grade students to increase the amount of time that they read each day at school and at home to support further the passage of the Third-Grade Summative Assessment. In the study, I examined the implementation of the Accelerated Reader Program to establish student reading goals and to enhance the school’s reading culture. I used teacher interviews, teacher surveys, and parent surveys in this study. The findings revealed that students who passed the Mississippi Third-Grade Summative Assessment increased their reading proficiency. A positive impact was made on the students’ reading proficiency, attitudes, motivation, …

Opportunity Restored: Using Creative Measures To Provide Students With Academic Advancement Opportunities Lost During Covid-19, Randal Clint Jordan

Electronic Theses and Dissertations

This mixed-methods action research study examines the Fast Track and Graduation Path (FTGP) programs—equity-focused interventions developed to offer opportunity to students who experienced academic disruption during COVID-19 emergency schooling (Creswell & Plano Clark, 2018). The programs targeted students retained due to socioeconomic status, learned helplessness, or the technology learning gap, rather than a lack of ability or low prior performance (Jenson, 2013; Maier & Seligman, 1976; Bower, 2019). FTGP provided structured academic pathways, daily facilitation, technology-based instruction, and character education to rebuild learner confidence and achievement (Reimer & Hill, 2022).

Quantitative data from the Edgenuity© learning platform revealed the program’s …

Purple To Powder Blue: Exploring Interactions Between Military-Connected Students With Disabilities And Student Services At The University Of Mississippi, Maura Mollet-Hobbs

Electronic Theses and Dissertations

This dissertation explores the interactions between military-connected students with disabilities (MCS/D) and student services at the University of Mississippi. As the population of MCSs in higher education continues to grow, partly due to expanded federal education benefits like the Forever GI Bill, a subset of these students face challenges related to their disabilities. This study focuses on MCS/Ds and examines how institutional support and policies intersect with their complex identities.

The research employs a mixed-methods approach to investigate how MCS/Ds interact with student services at the University of Mississippi, considering the intersection of their military connection and disability status. By …

Storytelling In Context: How Resources Enable And Constrain The Stories Entrepreneurs Tell, John J. Rogers

Electronic Theses and Dissertations

This dissertation investigates how entrepreneurial storytelling is shaped by and shapes its material and cultural context, extending the Theory of Cultural Entrepreneurship (TOCE). While TOCE highlights storytelling as a mechanism through which entrepreneurs construct legitimacy and secure resources by drawing on culturally resonant narratives, prior research has largely overlooked the constraining and enabling role of material resources in this process. This dissertation addresses this gap by examining how context functions, not merely as a backdrop but as a constitutive force in entrepreneurial storytelling. Using ethnographic methods, two studies were conducted at a regenerative farm and processing facility in rural Mississippi. …

Microgravity-Induced Effects On Global Gene Fitness And Secondary Metabolite Yield In Bacteria, Gayatri Sharma

Electronic Theses and Dissertations

Bacteria are ubiquitous and capable of colonizing nearly any environment, including extreme conditions such as deep oceans, high altitudes, and even space-faring vehicles. These vehicles present unique stresses not found on Earth such as microgravity and radiation. As space exploration advances, understanding how microgravity affects bacterial life has become increasingly important. Over the past 60 years, studies using both real and simulated microgravity have revealed species-specific responses, collectively indicating broad changes in bacterial function and physiological adaptations.

Initially, this study examined Novosphingobium aromaticivorans, a lignin-degrading bacterium detected in spacecraft cleanroom environments by assessing gene fitness during growth in microgravity on …

Examining Stress, Stress, Potentially Traumatic Events, Posttraumatic Stress Disorder, And Emotional Support Among Individuals With Skin Disease Symptoms, Taylor A. Strange

Electronic Theses and Dissertations

This study investigated the complex interplay between psychological stress, trauma-related experiences, and skin disease symptoms, alongside the potential moderating role of emotional social support. While the worsening effect of stress on skin conditions is well-documented, the specific association between trauma and dermatological symptoms, and its contribution to inflammatory responses, warrants further exploration. The stress-buffering hypothesis posits that perceived emotional support can mitigate the negative impact of stress on quality of life in chronic health conditions. This hypothesis has found support across various chronic physical and psychological ailments, yet its applicability to dermatological conditions remains less established. Our study pursued two …

Academic Achievement Variables: Significance Devalued By Correlated Variables, Ray J. Yancy

Electronic Theses and Dissertations

This correlational study investigates the relationship between student academic achievement and various external factors, including funding, student attendance, school attributes, and family income, across 147 Tennessee K-12 public school districts. Using Tennessee Comprehensive Assessment Program (TCAP) and End-Of-Course (EOC) scores to define student achievement, the study analyzes data from over 1900 schools during the 2023-2024 school year. Employing the statistical analysis software - SPSS - for descriptive and correlation analysis, the study excludes schools with incomplete data. The findings reveal significant correlations between student achievement and 80% of the external variables, rejecting the null hypothesis in 12 of 15 cases …

Loneliness And Ambulatory Blood Pressure, Patric Justin Leukel

Electronic Theses and Dissertations

Hypertension is a major risk factor for cardiovascular diseases and is by extension associated with potentially life-threatening events (e.g., heart attack, stroke). Loneliness, which has been linked to cardiovascular health problems, may be an important risk factor for hypertension. Most studies exploring psychosocial factors and blood pressure focus on single-point measurements of blood pressure, which have notable limitations. The current study investigated the association between loneliness and markers of hypertension (i.e., mean systolic and diastolic blood pressure, mean arterial pressure dip, average pulse pressure, and AASI) in a diverse sample by utilizing an ambulatory blood pressure monitoring (ABPM) device. Sixty …

Careers On The Spectrum: Enhancing Higher Education Career Services For First-Generation Neurodivergent College Students, Shyra Jannay Lynch

Electronic Theses and Dissertations

This study investigates the unique career service needs and experiences of first-generation neurodivergent college students (FGNCS) at the University of Mississippi. First-generation college students (FGCS), as the first in their families to attend college, often face distinct challenges in navigating higher education due to limited familial support and unfamiliarity with academic resources. Meanwhile, neurodivergent students, those with conditions such as autism spectrum disorder, ADHD, and various cognitive differences, encounter unique barriers related to sensory sensitivities, communication, and social integration within academic and career environments. At the intersection of these identities, FGNCS encounter distinct challenges in career services that may not …

Comparative Effectiveness Of Biologic Or Targeted Synthetic Disease-Modifying Antirheumatic Drugs In Terms Of Opioid Tapering And Discontinuation Among Medicare Beneficiaries With Rheumatoid Arthritis, Shadi Bazzazzadehgan

Electronic Theses and Dissertations

Objectives: Pain is the most common patient-reported outcome in rheumatoid arthritis (RA), frequently managed with long-term opioid therapy (LTOT), despite limited evidence supporting its efficacy and safety. Given the inflammatory nature of RA pain, biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) may relief pain and facilitate opioid withdrawal. This study compared rates of any opioid tapering, rapid opioid tapering, and opioid discontinuation among Medicare beneficiaries with RA who initiated b/tsDMARDs, including tumor necrosis factor inhibitors (TNFi bDMARDs), non-TNFi bDMARDs, or Janus kinase inhibitors (JAKi).

Methods: A new-user cohort study design was implemented using 5% Medicare (2012-2020). Beneficiaries with RA, …

Do College Students Delegate Over The Counter Product Choice To Pharmacists? A National Survey Experiment, Joanne Elizabeth Mansalay Canedo

Electronic Theses and Dissertations

Background: College students are known to have more frequent use for over-the-counter (OTC) cold products. Choice overload can lead to an increased burden of responsibility and dissatisfaction with one’s decision. The act of delegating to a pharmacist can prevent OTC product misuse and potential for abuse. The objective was to examine the effect of OTC choice difficulty and pharmacist accessibility on college students’ likelihood to delegate pharmacists for choosing OTC products for the common cold.

Methodology: An experimental within-subjects survey design was utilized on a national convenience sample of undergraduate students aged 18 years and older through Qualtrics market research …

Quantification Of Auxin-Cytokinin Response During Primary Root And Lateral Root Development In Common Bean, Gurdeep Singh

Electronic Theses and Dissertations

Roots support water and nutrient uptake, anchorage, and soil interactions through continuous growth at the primary root tip (PRT). In common bean (Phaseolus vulgaris), new cells are produced in an open root apical meristem and subsequently elongate in the elongation zone, and together these processes drive root tip progression through the soil. Lateral roots (LRs) arise in the differentiation zone, where pairs of pericycle founder cells dedifferentiate, divide asymmetrically, and form lateral root primordia (LRP) that pass through defined developmental stages before emergence. Auxin and cytokinin (CK) are central regulators of both primary root growth and LR development, yet their …

Afrissippi, Peter Muvunyi

Electronic Theses and Dissertations

This thesis examines how Guelel Kumba, a Senegalese Fulani griot, chef, and musician currently residing in Oxford, Mississippi, incorporates West African cuisine and music into his daily life in the South. This profile study asks: How does Kumba's performances and cooking translate Fulani heritage into Mississippi's blues and soul-food scenes? The research employed observation, secondary sources, purposeful semi-structured interviews, and a documentary.

Kumba views tradition as an arsenal, preserving its essential rhythms and flavors while reworking family recipes and tunes to suit local tastes. Customers can eat, listen, and interact their way into shared history at his food truck and …

Impact Of Minimally Processed Red Meat On Biomarkers Of Cognitive Decline, Saba Vaezi

Electronic Theses and Dissertations

No abstract provided.

Evaluation Of High-Moisture Ear Corn As A Roughage Source In Finishing Diets Fed To Beef Steers, Riley J. Leeson

Electronic Theses and Dissertations

The objective of this study was to evaluate the feedlot performance, rumination activity, and carcass characteristics of high moisture ear corn (HMEC) as a roughage source in finishing diets fed to beef steers. Backgrounded steers (n = 191; initial shrunk weight [4% BW] = 449 kg  23.9 kg) were assigned randomly to 1 of 24 pens (8 steers/pen) with pens randomly assigned to one of four dietary treatments (6 pens/treatment): control diet with hay fed at 10% roughage equivalency (RE; HAY10), or HMEC at either 14% (EAR14), 10% (EAR10), or 6% (EAR6) RE. High-moisture ear corn was assumed to …

A Research Project On The Feasibility Of The State Of California’S Mandate To Sell Only Zero-Emission (Electric) Vehicles By The Year 2035 For California And South Dakota, Sandeep Pudasaini

Electronic Theses and Dissertations

This research evaluates the feasibility of California's mandate to transition entirely to zero emission vehicles (ZEVs) by 2035 and explores the prospects of South Dakota adopting a similar policy. The study analyzes key factors such as infrastructure readiness, renewable energy capacity, material requirements for electric vehicle (EV) batteries, and socioeconomic variables that influence ZEV adoption. Feasibility studies like this are critical because large-scale policy mandates have far reached implications for energy systems, environmental outcomes, and economic planning. Understanding whether a state is equipped to meet such a goal allows policymakers to anticipate challenges, identify infrastructure gaps, and allocate resources more …

Comparative Evaluation Of Fungal Strains For The Bioprocessing Of Soybean Hulls Using Cheese Whey As Fermentation Medium, Ruchita Bhattarai

Electronic Theses and Dissertations

Globally, soybean is the most widely cultivated oilseed crops, and serve as the primary source of cooking oil, contributing to around 50% of global oilseed production. During the industrial processing of soybean oil, a significant amount of soybean hull (SH) is produced, which makes up about 8% of the grain yield, resulting in approximately 18–20 million tons of hulls, one of the largest by-products in the soybean industry. The hulls have limited commercial value and are primarily used as fiber additives in dairy cattle feed, but a large portion is still discarded as agricultural waste. Similarly, cheese whey (CW), a …

Quantifying Landscape Variability Of Dynamic Soil Properties In The James River Valley, Eastern South Dakota, Sage Reuter-Schmitt

Electronic Theses and Dissertations

Dynamic soil properties (DSP) are a great tool for monitoring land-use change, and they are frequently used as soil health metrics. The NRCS and other soil researchers often use repeating, single-point or nested-point DSP studies to monitor and better understand the effects of land management decisions. While these studies capture the temporal variability of DSPs, they overlook the field-scale spatial variability of DSPs. Soil organic carbon (SOC) provides critical services to the ecosystem and other environments. These traits, as well as its susceptibility to management decisions, make SOC an important soil health indicator and DSP. Measuring SOC is often time …

The Spatial And Temporal Dimensions Of Plant–Soil Feedback In Native Perennial Monocultures, Bret Lang

Electronic Theses and Dissertations

Plant-soil feedbacks (PSFs) describe how plants change their soil environment in ways that can either negatively or positively affect subsequent plant growth. In doing so, they offer an opportunity to connect ecological processes with agricultural practice. My dissertation examines PSFs created by native perennial monocultures, commonly used for native seed production, across time and space, and through soil legacies. Specifically, I focus on how plant species identity shapes both soil nutrient and soil microbial community responses. To address these questions, I conducted field experiments with monocultures of five forb species native to South Dakota and established plots with these species …

Impacts Of Early/Mid-Gestation Shearing On Umbilical Blood Flow And Lamb Birth Weight, Mara Johnson

Electronic Theses and Dissertations

Studies outside the USA have reported that shearing pregnant ewes during mid to late gestation increases lamb birth weight. Our hypothesis was that shearing pregnant ewes on day 50 of gestation would increase umbilical blood flow (UBF), fetal size, lambing and placental weights. Twenty-eight Polypay ewes were randomly assigned to two treatments: shorn (S) and sham-shorn (Control, CON) and divided in singleton (S: n=4; CON: n=4), twins (S: n=5; CON: n=5) and triplets (S: n=5; CON: n=5). Umbilical BF and fetal and placental measurements were obtained via ultrasonography every 10 days from day 50 to 110 of gestation. Lamb birth …

Impact Of Parental Involvement On Children’S Mental Health, Syeda Tasnime Kabir

Electronic Theses and Dissertations

This study estimates the causal effect of parental involvement on the mental health of primary school children in Bangladesh. Using an instrumental variables strategy that leverages local parental involvement norms, I find that increased parental involvement significantly reduces cognitive and emotional difficulties. Notably, I find that the protective effect of parental involvement varies by socio-economic context, showing weaker effects for children of mothers who married at an older age and those whose fathers live outside the household, but stronger effects in joint families. Furthermore, I identify two key mechanisms underlying these effects: accommodating parenting style and improved household hygiene practices. …

Isolation And Characterization Of Rhizobia Bacteria From Midwest Soils, Jr Loya

Electronic Theses and Dissertations

Symbiotic bacteria, known as rhizobia, can colonize the roots of legume plants and then convert atmospheric nitrogen into a usable form by the host through the process called biological nitrogen fixation (BNF). Many of these bacteria produce other plant-growth-promoting benefits, such as nutrient acquisition, phytohormone production, and the modification of plant stress responses. Agricultural inoculants made from these bacteria have helped reduce the need for man-made nitrogenous fertilizers, known causes of pollution and eutrophication. There are additional benefits in developing bacteria inoculants local to regional soils. The ability to survive and compete in Midwest soil and climates present an opportunity …

Deep Learning For Computer Vision Applications In Medical Diagnostics And Wildlife Monitoring, Mostapha Al Saidi

Electronic Theses and Dissertations

This dissertation explores innovative applications of deep learning and computer vision techniques across three distinct domains: medical imaging, dermatological diagnostics, and wildlife monitoring. The research addresses critical challenges in each field through the development and optimization of convolutional neural networks and other deep learning architectures.

The first study examines COVID-19 classification from X-ray images, comparing one-shot versus two-stage classification approaches using transfer learning with pre-trained models such as VGG16 and VGG19. The initial hypothesis was that breaking down the classification task into two optimized tasks would yield better results than one-shot classification. Results demonstrated that the single-stage approach achieved superior …

A Self-Sustaining Autonomous System For Long-Term Arctic Monitoring, Wenqiang Xu

Electronic Theses and Dissertations

The accelerated melting of Arctic sea ice poses critical challenges to global climate stability, marine ecosystems, and navigation safety. To address the need for continuous, high-resolution monitoring of the Arctic environment, this dissertation explores the development and feasibility of a Self-sustaining Autonomous System (SAS) for long-term Arctic observation. The proposed system is designed to overcome the limitations of traditional fixed or drifting buoys, as well as the range and endurance constraints of drones and Autonomous Underwater Vehicle (AUV)s, by utilizing a Small Waterplane Area Twin Hull (SWATH) Unmanned Surface Vehicle (USV) as a core observation platform. The wind-powered SWATH harnesses …

You Are Safe Here: A Phenomenological Exploration Of Psychological Safety And Organizational Ombuds In Higher Education, Angella J. Wint

Electronic Theses and Dissertations

This qualitative phenomenological study aimed to better understand the nature of ombuds’ psychological safety experiences in higher education by exploring how ombuds make meaning of their lived experiences with psychological safety and how it informs their roles with the constituencies they serve in higher education. Relying on data gathered related to the lived experiences of 12 organizational ombuds working at institutions of higher education, this study utilized one-on-one, open-ended, semi-structured interviews to collect data. The Four Stages of Psychological Safety was the conceptual framework used to study participants’ lived experiences. This study will contribute to the limited published empirical research …