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Pediatric Anxiety And/Or Depression Problems : Associations With Pm10, Fly Ash, And Metal Exposure., Abby Nicole Burns Hagemeyer

Electronic Theses and Dissertations

Background: In the last several decades, the use of coal has become more prevalent in turn increasing the amount of coal ash being produced. Coal ash, the by-product of coal combustion, is composed of small particles that contain essential elements, hazardous metals, polycyclic aromatic hydrocarbons, and radioactive material. While a small proportion of coal ash is reused, the majority gets discarded in open-air landfills and ash ponds. Fly ash, the major component of coal ash, can become emitted into the air and potentially contribute to the air pollution and metal exposure in the surrounding community. Few studies, particularly in the …

Function Of The Enterobactin Operon Of A. Actinomycetemcomitans In The Presence Of Catecholmines And Iron., Taylor Johnson

Electronic Theses and Dissertations

Background: Aggregatibacter actinomycetemcomitans (Aa) possesses a two-component system, QseBC, which is key in biofilm formation/virulence and is activated in the presence of iron-catecholamine complexes. Aa does not synthesize enterobactin, a catechol-based siderophore, yet possesses the machinery for recognition and uptake. We hypothesize that Aa is able to acquire iron by catecholamine mediation through the enterobactin receptor/transporter. Methods: By insertional mutation, we attempted to delete the enterobactin permease from the genome using suicide vector pJT1. A growth curve of truncated mutant ΔfepA was also conducted to observe growth in the presence of iron and catecholamines. Statistical significance was determined by ANOVA …

Inhibition Of Chemotherapeutic-Induced Apoptosis In Esophageal Squamous Cancer Cells By The Keystone Periodontal Pathogen, Porphyromonas Gingivalis., Atul Kumar Agrawal

Electronic Theses and Dissertations

Recent evidence has shown that P. gingivalis, a Gram-negative, anaerobic oral bacterium, is negatively associated with the presence and outcome of esophageal squamous cell carcinoma (ESCC). While potential underlying mechanisms are yet to be established, P. gingivalis infection is known to inhibit apoptosis in gingival epithelial cells. Therefore, we hypothesized that P. gingivalis may also inhibit of the induction of apoptosis in human ESCC cells exposed to the commonly employed anti-ESCC chemotherapeutic agent, cisplatin. The capacity of P. gingivalis, at variant multiplicities of infection, to suppress cisplatin-induced necrosis and apoptosis in EC9706 ESCC cells was established by lactate …

Combating Malignant Melanoma With The Multifaceted Soy-Dervied Peptide Lunasin., Christopher Paul Shidal

Electronic Theses and Dissertations

Lunasin is a 44 amino acid peptide that has been shown to have cancer chemopreventative and chemotherapeutic properties. This study investigated the potential utility of Lunasin as a chemotherapeutic in melanomas. Studies showed that Lunasin had little activity against established melanoma cell lines using adherent culture methods; however, Lunasin’s in vitro activity was significantly higher in non-adherent colony-forming assays and oncosphere formation. These results led to the investigation of whether or not Lunasin has selective effects on cancer initiating cells (CIC) that are known to be present in melanomas. It was revealed that Lunasin selectively inhibited the proliferation of high-ALDH …

Colorectal Cancer Fit Screening In The Hope Vi Population Of Jefferson County, Kentucky., Jeffrey D. Stone

Electronic Theses and Dissertations

Using pre-post survey data collected from 209 randomly selected African American people from the population of former residents of Clarksdale and Sheppard Square public housing areas, this study explores the relationship between individual characteristics and colorectal cancer screening behavior, measured by the uptake of the Fecal Immunochemical Test (FIT) and by prior colorectal screening, while controlling for neighborhood factors and geographic proximity to healthcare facilities. This particular public housing population is of interest because of their relocation from the downtown area, where healthcare facilities are within walking distances, to other public housing units either in large apartment complexes or scattered …

Untangling The Role Of Postsecondary Education In Economic Success., Erin Smith Banjanovic

Electronic Theses and Dissertations

This dissertation explored the relationship between postsecondary education and economic success through a person-centered lens. A sample of 365,315 employed individuals between the ages of 25 and 35 from the American Community Survey (ACS) were used in combination with data from three occupational databases (O*NET, the Occupational Outlook Handbook, the NORC occupational dataset) to examine this topic. The various sources of data were merged together by occupation to permit examination of occupational characteristics and creation of two measures of education and occupation match: 1) match in education level attained and required, and 2) match in field of study and field …

Transversal Approaches And Ecological Artwork., Madison Deanna Sevilla

Electronic Theses and Dissertations

This work explores systematic ecology as it relates to sculpture and language. This project exists in two parts: a written thesis and a thesis exhibition. Although both works explore ecological systems, Unseen: Visualizing Ecological Systems investigates visualizations and concepts of the ecological, whereas this thesis continues the exploration into the ramifications of disruptions in systems. Ecological systems such as the environmental, social/mental, economic, and political define the foundations of our known world and encapsulate all regions of society. No single system can function independently of the rest and all systems contain some aspect of human-system involvement. By using the work …

Development Of Recyclable Gold Nanoparticles For Routine Benchtop Catalysis In Organic Transformations., Shengzong Liang

Electronic Theses and Dissertations

Homogeneous gold catalysis is a popular research area due to its high efficiency. Various gold catalysts have been utilized in organic synthesis and their reaction mechanisms are also well understood. However, most gold catalysis suffers from high catalyst loading or catalyst decay problems. In addition, homogeneous gold catalysts are not recyclable. These disadvantages have limited their application in large-scale synthesis and also caused a serious waste of this precious metal. A solution for these problems is to use a recyclable heterogeneous gold catalyst. So in this study, with the aim of making gold chemistry greener we successfully used heterogeneous gold …

A Tool To Evaluate Sustainability Of Pavement Maintenance Projects., Yibo Zhang

Electronic Theses and Dissertations

Pavement maintenance activities are widely regarded to be critical elements during pavement life cycle, different maintenance techniques have been used to restore or extend the service lives of pavements. However, the existing maintenance practices on pavement system have problems that impair the economic benefits, disturb the natural environment, and somewhat ignore the needs from stakeholders. To minimize these negative impacts, sustainability is an ideal way because it addresses the problems under Triple Bottom Line (TBL, refers to economy, environment, and society). Sustainability analysis within transportation or pavement industry has been studied in different countries, but the concept of sustainable pavement …

Expression Of Zeb Factors In Oral Squamous Cell Carcinoma., Saira Ahmed

Electronic Theses and Dissertations

Objectives: The ZEB family of transcription factors (ZEB1 and ZEB2) have been demonstrated to play a role in metastatic progression of several cancers, and may also influence the initial transformation and generation of cancer stem cells. However, the expression pattern of ZEB proteins in the development of oral squamous cell carcinoma has not been investigated. The purpose of this study was to define changes in expression and subcellular localization of the ZEB family in both precancerous lesions and different grades of OSCC. Materials and Methods: Seventy-nine tongue biopsies were subjected to immunohistochemistry and immunofluorescence to determine the expression and subcellular …

Student Self-Assessment Of Operative Dentistry Experiences : A Time Dependent Exercise In Best Practice Outcomes., Celine Joyce Cornelius Timothius

Electronic Theses and Dissertations

Purpose: The purpose of this project was to evaluate student self-assessment of operative dentistry experiences. Methods: First, a retrospective analysis of student self-assessment and faculty assessment grade sheets were evaluated for mean differences and correlations across time. Both preclinical (D2: n=120) and clinical (D3: n=120; D4: n=120) grades sheets were evaluated. Secondly, twenty-five (n=25) students from each of the D1, D2, D3 and D4 classes were asked to evaluate dentoform work. Twenty-five (n=25) operative calibrated faculty graded the same two dentoforms. Results: D2 student’s self-assessment scores were significantly higher than the faculty assessment scores (t-test; p0.05) and there was a …

The Interaction Of Homoserine Lactones And Paraoxonase 2 Modulates Cell Death Signaling And Cell Proliferation., Aaron Mackallan Neely

Electronic Theses and Dissertations

Pseudomonas aeruginosa produces N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule that functions to facilitate bacteria-bacteria communication. C12 has also been reported to affect many aspects of human host cell physiology, including evoking cell death in various types of cells. However, the signaling pathway(s) leading to C12-triggerred cell death remains unclear. To clarify cell death signaling induced by C12, we examined mouse embryonic fibroblasts (MEFs) deficient in one or more caspases. Our data indicate that, unlike most apoptotic inducers, C12 evokes a novel form of apoptosis in cells, probably through the direct induction of mitochondrial membrane permeabilization. Importantly, C12 induces apoptosis …

The Effect Of Role Assignment And Personality Subtypes In Simulation On Critical Thinking Development, Situation Awareness, And Perceived Self-Efficacy Of Nursing Baccalaureate Students., Dustin Travis Weiler

Electronic Theses and Dissertations

Previous studies have evaluated the effectiveness of high fidelity patient simulators (HFPS) on nursing training. However, a gap exists on the effects of role assignment and student personality subtypes in simulation scenarios. This thesis explored the effects of role assignment and personality on critical thinking, situation awareness, and self-efficacy in baccalaureate-level nursing students. Using researcher-developed tools and altering previously validated tools to fit the simulation scenario, the effects of role assignment and personality were determined. Role assignment and personality were found to have a significant effect on critical thinking and self-efficacy, but not situation awareness. It was determined that roles …

Evidence-Based Intervention That Decreases Stress Levels In Teens Who Are Missing School Due To Outside Stressors, Madysen Pennington

Electronic Theses and Dissertations

The purpose of this thesis is to test the effectiveness of an intervention designed to reduce

stress in adolescents. StressOFF Strategies program is the intervention used to educate students about stress and how to effectively manage it. A group of 8-10 students from Abilene High School was recruited to participate in the study during their one-hour lunch period. The tools used for the intervention included the StressOFF Strategies PowerPoint, the My Personal Stress Profile, and the Perceived Stress Scale. The findings are presented on individual graphs that show increases and decreases in stress levels for each student. Implications suggested are …

Attachment To God, Locus Of Control, And Outcomes In The Brief Alcohol Screening And Intervention For College Students, Misty Schoephoerster

Electronic Theses and Dissertations

Research shows that aspects of religion and spirituality can influence drinking behavior among university students. Some believe that an internalized commitment to God, or to another spiritual force, is an important component in explaining relationships between religion, spirituality, and drinking behavior. One way of understanding and measuring this internalized commitment to God is based on attachment theory. Another way of measuring and understanding internalized beliefs about the degree to which God shapes behavior is based on the social learning theory concept called locus of control. Conceptually, low God locus of control indicates that one believes God is passive and not …

It’S About ‘That Time’ To Break The Cycle: A Rhetorical Analysis Of Challenging Menstrual Taboos, Audrey Marie Lamborn

Electronic Theses and Dissertations

Menstrual taboos exist around the world, and while new conversations are starting to address these issues, in many regions these taboos limit women’s daily lives and can even lead to serious health problems. Artifacts around the world are starting to emerge to challenge these preconceived notions and bring menstrual hygiene awareness as well as products to women in need. While the origination of the menstrual taboo is not clearly defined, various literature discusses both the cultural and religious origin and perpetuation of menstrual taboos. This thesis examines various artifacts found in the regions of the United States and the United …

Evaluation Of The Impact Of Social Work Services In Rural School Districts, Breanna Heinrich

Electronic Theses and Dissertations

Students in rural communities are often subject to unique barriers and challenges that impact their holistic emotional, cognitive, physical, and social success in school. Because these factors have a strong impact on school attendance, behavior, and overall success, educators have begun to implement social work programs within both rural and urban school districts across the nation. While existing research affirms the effectiveness of school social work, very little research has been conducted to determine the effect in rural school districts. This paper evaluates the impact of a newly developed social work pilot program in two West Texas school districts implemented …

Does Homelessness Increase The Risk Of Readmission In Acute Care Patients Diagnosed With Schizophrenia, Lindsey N. Marek

Electronic Theses and Dissertations

This thesis attempts to answer a research question: Does homelessness contribute to the readmission of acute psychiatric admission with those diagnosed with schizophrenia? A quantitative, retrospective study was conducted using a sample of one hundred and thirty-six patients who were admitted to an acute care hospital in Texas between the dates of January 01, 2015 through December 31, 2016. Data were collected from existing patient records of an acute care hospital located in Texas. The results show that homelessness was a significant predictor in treatment readmission. More specifically, homelessness was a contributing factor of readmission due to being suicidal. It …

Gender, Population Type, And Coping As Predictors Of Ptsd Symptom Severity, Stacey A. Kerr

Electronic Theses and Dissertations

Research has demonstrated that a salient predictor of PTSD is experiencing a traumatic event. Additional research has indicated that there are other risk factors involved with predicting the development of PTSD including gender, population type, and emotion-focused coping. The purpose of the current study was to examine gender, population type, the interaction effect between gender and population type, and emotion-focused coping, specifically avoidant emotional coping and active emotional coping, as independent predictors of PTSD symptom severity. In total, 124 individuals participated in the current study. The sample consisted of 64 civilians and 60 military personnel. The results indicated that gender …

English Proficiency Associated With The High School Grades Of Lep Students In Abilene Isd, Donald A. Dolton

Electronic Theses and Dissertations

In recent years, immigration into the U.S. has increased because of growing economic problems around the world. Economic globalization and technological developments (internet access and the ability to move massive amounts of information and people in a short amount of time) have influenced the number of those seeking asylum. Accordingly, the U.S. school system continues to see an increase in students who are culturally diverse with greater educational deficiencies and limited English proficiency (LEP). In Texas there has been a 90% increase in the number of immigrants from 1990 to 2010 (National CE). This means that currently immigrants make up …

Playing With Usability: Why Technical Communicators Should Examine Mobile Games, Alexandra Cata

Electronic Theses and Dissertations

This thesis examines how technical communicators can look to free, successful mobile games for mobile User Interface (UI) and User Assistance (UA) inspiration and design techniques. The purpose of this thesis is to provide an overview of major game studies theories and situate them within technical communication theory and practices. Technical communicators can leverage game studies theories to augment existing technical communication theories and practices. Specifically, I examine cognitive learning theory in game design, game usability, playability, and user-centered design, and how these theories relate to technical communication, rhetorical, mobile UI/UA, and general usability theories and methods. Additionally, I also …

Grace Hopper And The Marvelous Machine: Lessons For Modern Technical Communicators From The Mark I Ascc Manual, Jessica Meyr

Electronic Theses and Dissertations

Women's technical writing achievements often go unrecognized, both due to the invisibility of technical writing professionals in general, and a lack of famous technical communication role models in particular. The purpose of this thesis is to analyze and present an early major work in the technical writing of Rear Admiral "Amazing" Grace Hopper, inventor of the compiler and an important figure in computer science history. Although Hopper is arguably best known for popularizing the idea of the "computer bug," her achievements in computer science extend from invention of the software compiler to tireless promotion of the programming language COBOL. Her …

Fluorescence Lifetime Imaging And Spectroscopy Aided Tracking Of Zno And Cds:Mn/Zns/ N-Acetyl Cysteine (Nac) Quantum Dots In Citrus Plants, Torus Washington

Electronic Theses and Dissertations

In this thesis, we present an efficacious way of tracking nanoparticle movement in plant tissue through the use of fluorescence lifetime imaging (FLIM) and spectroscopy as well as a review of nanoparticle uptake in plants and the proposed mechanisms governing them. Given the increasing number of nanomaterials in agriculture and society as a whole, proper imaging tools and proactive measures must be taken to track nanoparticle movement in plant tissues and create infrastructure and products to keep things sustainable and safe. Herein we report a ZnO comparable nanoparticle— a CdS:Mn/ZnS/ N-acetyl cysteine (NAC) quantum dot— which boasts longer lifetimes and …

Use Of Performance Information By Local Government Administrators: Evidence From Florida, Tamara Dimitrijevska-Markoski

Electronic Theses and Dissertations

This study examines the factors that facilitate and hinder the use of performance information by public administrators in local governments in Florida. Acknowledging the incompleteness of many theoretical and conceptual models in previous performance management studies and the absence of theory on the use of performance information; this study utilizes a grounded theory approach to develop and test a model analyzing the use of performance information. The research focuses on cities and counties, members of the Florida Benchmarking Consortium (FBC), and surveys public administrators whose tasks are related with the collection and/or reporting of performance information. The study examines three …

The Potential Of Green Care Interventions To Promote Positive Youth Development With A One Health Lens, Hagit Brandes

Electronic Theses and Dissertations

The first part of this study is making a conceptual tie between three distinct bodies of knowledge: Green Care, Positive Youth Development (PYD), and One Health. Green Care is an organizing construct for various interventions that use nature as a framework. I suggest that a nature-based program which incorporates Animal-assisted and horticulture interventions have the potential to promote positive youth developmental outcomes. The two major tenets of the PYD model are the mutually influential and bi-directional relationship between an individual and their context, and this relationship characteristic of plasticity, the potential for change (Lerner, 2006). Plasticity is viewed as an …

Family Engagement In Postsecondary And Workforce Readiness In A Suburban School District: An Exploratory Study, Keisha Kayon Morgan

Electronic Theses and Dissertations

As the focus on graduating all students and preparing them for postsecondary pursuits increases, schools are examining their practices in supporting how students are successfully prepared (Gutmann, & Ben-Porath, 1987; Guilfoyle, 2013). This study examined how the diversity of the family structure that now permeates modern day society can be used as a true partnership that embraces inclusivity and as a credible component to the postsecondary pursuits of students. Through the lens of the existing literature and a new theoretical framework, The Model of Family Engagement in Postsecondary and Workforce Readiness (FEPWR), the researcher identified the intersections between family engagement …

Analyzing Electricity Use Of Low Income Weatherization Program Participants Using Propensity Score Analysis And A Hierarchical Linear Growth Model, Ksenia Polson

Electronic Theses and Dissertations

This evaluation utilized propensity score matching methods and a longitudinal hierarchical linear growth model to determine the effect of residential energy efficiency upgrade(s) on household electricity use for the low-income community over the course of a year in the City and County of Denver, Colorado. Propensity score analysis with risk set matching was performed at each month under analysis applying nearest neighbor and nearest neighbor with caliper approaches by balancing covariates across the treatment and control groups. Following the completion of propensity score analysis, the data were aggregated to form a data set that was used in a hierarchical linear …

A Mixed Methods Examination Of Pregnancy Attitudes And Hiv Risk Behaviors Among Homeless Youth: The Role Of Social Network Norms And Social Support, Stephanie J. Begun

Electronic Theses and Dissertations

Homeless young women become pregnant at exceptionally high rates, and such pregnancies often pose serious emotional, social, and physical health concerns. Perhaps surprisingly, many homeless youth intentionally seek to become pregnant or involved in pregnancy, as pregnancy and parenthood are viewed as conduits toward accessing social services and meaningful social connections to others that this group often lacks. However, most prevention efforts focus solely on young females' pregnancy attitudes and behaviors at the individual level. Such approaches fail to acknowledge contextual factors, such as desired pregnancy and pregnancy ambivalence, the influence of youths' social networks and perceived social norms regarding …

Points Of Leverage: Interrupting The Intergenerational Transmission Of Adversity, Lisa Schlueter

Electronic Theses and Dissertations

Early life stressors, such as abuse and neglect, have been associated with poor physical and mental health outcomes in adulthood. Moreover, animal models suggest that caregivers' early life stress can have intergenerational effects that then impact the health and well-being of their offspring. Although animal models are compelling, and inter-generationally transmitted and co-occurring risks are well-documented, proximal mechanistic explanations for how caregiver's history of childhood adversity can result in changes to their child's stress physiology and outcomes have not yet been systematically tested in humans. Thus, among a sample of low-income, predominantly Latino families participating in Early Head Start (EHS), …

Engaging The Brave And The Bold: Exploring The Discourses Of Disability Through Life Stories, Brian L. Grewe Jr.

Electronic Theses and Dissertations

Understanding the meaning making of having an acquired physical disability still remains a mystery today. With more than 20 percent of our total population experiencing some form of disability, this study explores discourses of disability that emerge from participants' life stories. This study interviewed 20 participants using a modified version of McAdams' (1993) Life Story Interview Protocol. Utilizing Relational Dialectics Theory and a thematic discourse analysis, two primary discourses emerged from participant talk. (1) the biomedical discourse of disability and (2) the disability discourse of normalcy. The latter discourse can be broken down even further into (1) the sociolinguistic discourse …