Digital Commons Network^™

Characterization Of The Dimerization And Salt Dependent Aggregation Of The Als-Linked Protein Tdp-43, Elizabeth Ehrhardt

Electronic Theses and Dissertations

Trans-active response (TAR) DNA-binding protein 43 (TDP-43) is essential for RNA processing but can also form toxic cytoplasmic inclusions in neurons of patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). RNA-binding has been shown to have the potential to decrease or inhibit the aggregation of TDP-43, indicating that supplying RNA therapeutics may be a solution to treat these neurodegenerative disorders. However, the mechanism of aggregation, transitioning from TDP-43’s native dimeric state to small oligomers to toxic aggregates, is still relatively unknown. This needs to be established before determining how to target and disrupt this aggregation. Using GFP-TDP-43, …

Caballerismo In Latinx Men In Higher Education, Victor Carrasco

Electronic Theses and Dissertations

Latinx men continue to be marginalized in higher education, and more research is needed to understand how to retain them using anti-deficit frameworks (Cook et al., 2012). Studies have investigated caballerismo as a protective factor for LatinX men. Caballerismo is defined by egalitarian beliefs, affiliation, positive family relationships, and empathy (Arciniega et al., 2008; Neff, 2001). Despite its promise as an anti-deficit framework, little is known about how caballerismo informs Latino students’ experiences in higher education. Therefore, this study addresses the following research questions: a) How does caballerismo manifest in Latinx men in higher education, b) how does caballerismo intersect …

How Parents, Teachers, Psychologists, And Educational Environments Influence Developmental Transitions Of Preadolescent Twice-Exceptional Students, Karen B. Arnstein

Electronic Theses and Dissertations

The purpose of this collective case study was to examine the perceived developmental transitions of preadolescent, twice-exceptional students to understand both the supports and barriers from the perspective of parents, teachers, and psychologists. The case for this study, located in a western U.S. state, was a private school educating twice-exceptional students. The research questions guiding the study included the following: How do parents perceive growth in both academic and psychosocial development? How do educators perceive growth in both academic and psychosocial development? What are the supports that promote successful developmental transitions? What are the barriers that inhibit successful developmental transitions? …

Photographs In My Mind, Through Darkness And In Light: An Auto-Criticism Of A University Teacher, Melanie Renee Witt

Electronic Theses and Dissertations

This dissertation is an auto-criticism, a new qualitative inquiry founded in educational criticism and arts-based research, which describes and analyzes my lived experience as a female university teacher. The purpose of this study is to describe, interpret, evaluate and thematize my experiences with professional stress, pregnancy loss, and self-care. Secondly, it illuminates auto-criticism as a methodology with potential contributions to qualitative research and higher education.

Personal documents, internal artifacts, and external artifacts generated during a challenging period of my life as a university teacher are used as data. Language and photography combine to story my lived experiences and findings.

This …

Comprehensive Research Synthesis: An Approach To Mixed Methods Research Syntheses, Lilian Linialy Chimuma

Electronic Theses and Dissertations

Mixed methods research synthesis (MMRS) is an emerging application of both mixed-methods research (MMR) and review research. MMRS promises to comprehensively address intricate contemporary research and evaluation questions given diverse evidence sources (across quantitative, qualitative, and MMR primary studies). The significance of concurrently addressing methodological issues for new research developments is widely noted in the literature. Current efforts attempt to streamline methodological practices along with application of the MMRS approach. Researchers have proposed conceptual frameworks to guide the application and practice of MMRS studies. Despite these efforts, complications and disagreements persist. In response to these concerns, this study developed a …

A Phenomenological Study Of The Lived Experiences Of Counselors In Training When Discussing The Existential Factors Of Death, Isolation, Freedom, And Meaning In Life With Their Clients, Sabina Musliu

Electronic Theses and Dissertations

Grounded in the theoretical framework of existential therapy, this study aimed to uncover the lived experiences of counselors in training when addressing existential factors of death, isolation, freedom, and meaning in life with their clients. To have a better understanding of this phenomenon and address the research questions, data was primarily collected via semi-structured interviews. The obtained data was analyzed using an interpretative phenomenological analysis (IPA). The data analysis process revealed six superordinate themes from the participants’ experiences: the emotional experience in the session and during the interview; transference/ countertransference; perspective on existential factors; factors that influenced counseling effectiveness in …

The Experiences Of Ncaa Student-Athletes With An Eating Disorder Or Disordered Eating, Rachel E. Taylor

Electronic Theses and Dissertations

The purpose of this study was to explore the experiences of student-athletes who had an eating disorder or disordered eating (ED/DE) while competing for the National Collegiate Athletic Association (NCAA). Integrating criticism and connoisseurship and critical evocative portraiture, four post-collegiate women who participated in cross country and track, who were either clinically diagnosed with an ED/DE or who self-diagnosed, participated in two interviews to describe their experiences with and the impact of ED/DE on their athletic pursuits, academic pursuits, as well as their relationships with coaches, teammates, and family. The analysis of these interviews showed the complexity of this topic. …

Human Genetics, Psychotropic Drugs, And Acts Of Violence, Selma Jolanda Eikelenboom-Schieveld

Electronic Theses and Dissertations

From the start of the use of psychoactive prescription medications in the 1950s, physicians reported paradoxical adverse reactions, ranging from newly developing depressions to an increase in existing mood disorders, and extremely violent and bizarre acts of suicide and homicide. In this research, it is hypothesized that the pharmacological properties of the prescribed drugs or the interaction between the drugs and the enzymes that are primarily responsible for their metabolism (cytochrome P450s) could cause these reactions. Given that acts of violence could be medication-induced, the role of the rate of drug metabolism is discussed. Genetic testing of certain CYP450s could …

Poverty In The United States: An Analysis Of Its Measurement And The Long-Term Social And Economic Costs, Abby Magnus

Electronic Theses and Dissertations

This thesis examines the role of poverty in the United States and how it has impacted social and economic systems. It explores how U.S. poverty measurements developed in the 1960s may not be accurately measuring poverty now, and the ways in which these measures could be improved upon. This work also reviews literature on health and educational inequities stemming from socioeconomic class, and the role these play in long-term economic mobility. Finally, it analyzes how larger social institutions like mass incarceration and capitalism have developed around poverty, and the role they play in maintaining its prevalence today. This thesis finds …

System Update: Technology Based Intervention For Students With Intellectual And Developmental Disabilities, Marisa C. Simoni

Electronic Theses and Dissertations

Post-school outcomes are unfavorable to students with intellectual and developmental disabilities (IDD). Despite these outcomes and significant academic challenges, students with IDD have the potential to learn adaptive and life skills that lead to a more independent and fulfilling life through intentional intervention strategies. This dissertation explores technology-based interventions for students with IDD. Manuscript 1 presents a synthesis of literature related to technology, IDD, and a system of supports that schools utilize for tiered intervention delivery. Based on the findings, a new framework, Systems of Support for Technology Intervention (SSTI), is introduced to help guide school psychologists in choosing appropriate …

Land Use Influences Along Elevation Gradient On Macroinvertebrate Communities, Brittany Sprout

Electronic Theses and Dissertations

Land use activities have caused disturbances that affect the quality of freshwater ecosystems worldwide. How the influences of land use along an environmental gradient and the associated environmental variables that may influence stream diversity and function is unclear. We address these issues by studying biodiversity, abundance, and functional diversity of macroinvertebrates across different land types along a gradient in Colorado, USA. We also address how diversity may change along an elevation gradient by analyzing previously published macroinvertebrate research. We found evidence that land use and disturbance are stronger explanations of changes in macroinvertebrate communities, rather than elevation. Functional trait patterns …

Identification Of Gifted Characteristics Using The Behavioral Assessment Scale For Children—Third Edition, Kristine Zytka

Electronic Theses and Dissertations

Children who are gifted are at-risk for being misidentified with emotional and behavioral disorders (Daniels & Piechowski, 2009; Mullet & Rinn, 2015; Webb, 2016). Challenges exist in conclusively defining giftedness, assessing giftedness, and understanding common behavioral patterns among gifted individuals (Bracken & Brown, 2006; McClain & Pfeiffer, 2012). Because gifted children typically exhibit common behavioral patterns, it is important for school psychologists to understand gifted behavioral characteristics, how to assess these characteristics, and how to differentiate between common gifted behavior and maladaptive behavior (Daniels & Piechowski, 2009; Webb, 2016). This study examined the value of the BASC-3 in identifying gifted …

Xylo-Bot: A Therapeutic Robot-Based Music Platform For Children With Autism, Huanghao Feng

Electronic Theses and Dissertations

Children with Autism Spectrum Disorder (ASD) experience deficits in verbal and nonverbal communication skills, including motor control, emotional facial expressions, and eye gaze / joint attention. This Ph.D. dissertation focuses on studying the feasibility and effectiveness of using a social robot, called NAO, and a toy music instrument, xylophone, at modeling and improving the social responses and behaviors of children with ASD. In our investigation, we designed an autonomous social interactive music teaching system to fulfill this mission.

A novel modular robot-music teaching system consisting of three modules is presented. Module 1 provides an autonomous self-awareness positioning system for the …

Sex, Love, And Masturbating: A Touchy Subject, Gabrielle Kaminsky-Bayer

Electronic Theses and Dissertations

The topic of female masturbation has long been considered taboo and this has impacted the sparse research on female masturbation. In addition to the limited literature that exists on women’s reasons for masturbating in general, there are even fewer studies regarding the motivation for women to masturbate while in a relationship or how masturbating in a relationship impacts relational and sexual satisfaction. To date, there has been no study that specifically looks at early adult women (25-35 years old) in relationships that assesses the attitudes and behaviors of masturbation on relational and sexual satisfaction. Additionally, this paper was structured …

Rhetorical Genealogy And The Ethics Of Eugenics, David Mark Thomas

Electronic Theses and Dissertations

This dissertation strives to critique contemporary rhetoric on eugenics. In recent years, scientists succeeded in mapping the human genome and subsequently developed new gene editing technologies. To situate current ethical discourses about eugenics, I trace histories of these discourses at several scales of society – from the macroscopic level of the body politic to the meso level where modes of assessment have been deployed purportedly to accurately evaluate human characteristics to the microscopic level of the gene. I employ Foucauldian genealogy to highlight how, despite marked differences over time in specific eugenic discourses and practices exist, the underlying rhetoric has …

Behind The Exhibit: Exploring The Processes Of Indigenous Rights Representation At The Canadian Museum For Human Rights, Madison Caroline Dillard

Electronic Theses and Dissertations

Focusing on the representation of Indigenous human rights at the Canadian Museum for Human Rights (CMHR) in Winnipeg, Manitoba, this study examines how museums can represent, educate, and advocate for Indigenous human rights. The study is based on ethnographic fieldwork carried out at the museum in July 2019 and the literature on anthropology and human rights, decolonizing museum practices, and museums as spaces for human rights dialogue. The study shows how museums can change their history of racist and inaccurate representation of Indigenous people. Through extensive and “deep collaboration” between Indigenous partners and museum staff, Indigenous culture, history, and rights …

Certification-Driven Testing Of Safety-Critical Systems, Aiman S. Gannous

Electronic Theses and Dissertations

Safety-critical systems are those systems that when they fail they could cause loss of life or significant physical damages. Since software now is an essential component of these types of systems, failures caused by software faults could come from flaws in the software development life-cycle. As a result, challenges unfold in two directions. First, in verifying that the software will not put the system in an unsafe state, and identifying external failures and mitigate them properly. Second, in providing sufficient evidence for an efficient safety certification process. In this study, we propose an approach for testing safety-critical systems called Model-Combinatorial …

Aggregated Der Management In Advanced Distribution Grids, Mohsen Mahoor

Electronic Theses and Dissertations

Evolution of modern power systems are more distinct in distribution grids, where the growing integration of microgrids as well as distributed energy resources (DERs), including renewable energy resources, electric vehicles (EVs), and energy storage, poses new challenges and opportunities to grid management and operation. Rapid growth of distribution automation as well as equipment monitoring technologies in the distribution grids further offer new opportunities for distribution asset management. The idea of aggregated DERs is proposed as a remedy to streamline management and operation of advanced distribution grids, as discussed under three subjects in this dissertation. The first subject matter focuses on …

Early Childhood Educator Knowledge: An Exploratory Study Regarding Giftedness And Students Of Color, Stephanie A. Peralta

Electronic Theses and Dissertations

The purpose of this study was to examine general early childhood educator knowledge and perceptions of curricula relevant for early childhood gifted students of color. The research questions that guided the study were the following: How does preschool through second grade curricula support or impede academic success for gifted students of color? How does preschool through second grade curricula support or impede social emotional learning for gifted students of color? What are the perspectives of educators regarding inclusive practices including Critical Race Theory, within a preschool through second grade gifted curricula?

In reviewing the literature and national data concerning representation …

Cultural Wealth Of First-Generation College Students And Its Effects On Well-Being, Persistence, And Major Satisfaction, Eve M. F. Sussman

Electronic Theses and Dissertations

Although understanding of FGCS’s success in higher education has been enhanced over the last decade, less is known about their career and educational development, and how their strengths and assets promote college success. The purpose of this study was to explore the relations between first-generation college student (FGCS, [N= 130]) cultural wealth variables, work volition, and outcomes (i.e., academic major satisfaction, persistence, and well-being) using the Critical Cultural Wealth Model (CCWM; Garriott, 2020). Results of regression analyses partially supported CCWM propositions. Significant, positive correlations were observed between resilience and work volition, academic major satisfaction, and well-being. Significant, positive …

Living The Dream: Building Self-Determination To Improve Postsecondary Outcomes, Pete Gladstone

Electronic Theses and Dissertations

Despite recent federal legislation outlined in the Individuals with Disabilities Education Act (IDEA) reauthorization of 2004 that mandates effective postsecondary transition planning for all students with Individualized Education Programs (IEPs), students with intellectual disability (ID) continue to experience inequitable postsecondary outcomes, particularly in the areas of postsecondary education (PSE), employment, and independent living (Lipscomb et al., 2017). It has been established that one effective method for improving those outcomes is to develop students’ self-determination abilities, and there is near unanimous agreement within the education community that doing so should be a primary objective during the transition process (Izzo & Lamb, …

Disrupting Disparity: A Critical Race Transformative Mixed Methods Examination Of School Discipline, Ceema Samimi

Electronic Theses and Dissertations

Racial disparities in school discipline are well-established in the United States’ public-school system. These disparities contribute to a phenomenon known as the school-to-prison pipeline. This phenomenon is a metaphor for the mechanisms that push students, especially students of color, out of school and into the justice system. While research has examined the causes and impacts racial disproportionality in discipline, no studies have focused on schools with no disparities. This study used Critical Race Transformative Mixed Methods to examine school-level quantitative data while employing phenomenological methods to interviews with 12 teachers using critical race theory as a lens. Findings revealed that …

Social Support Among Undergraduate Students: Measure Development And Validation, Heather M. Blizzard

Electronic Theses and Dissertations

Being born into circumstances of low-income, having a racial minority status, and/or non-college educated families dwindle the opportunities for many students to obtain a college degree (Cox, 2016; Engle & Tinto, 2008; Jenkins et al., 2013). While many institutions of higher education have diligently worked to develop programs geared towards attending the educational inequalities among diverse student populations, there is still a great need for programs centered on the inequalities surrounding social support (Cox, 2016; Ward et al., 2012; Soria & Stebleton, 2012).

The purpose of this study was to develop and assess a measure to examine perceived social support …

Age Bias In Clinical Judgment: Moderating Effects Of Ageism And Multiculturalism, Kristin Pyne

Electronic Theses and Dissertations

The proportion of older adults in the United States is growing rapidly (U.S. Census Bureau, 2014) and mental health concerns in older adults are expected to increase rapidly (Choi, DiNitto & Marti, 2015). Despite increasing caseloads of older adults, few practicing psychologists have received specific training or specialization in geropsychology (American Psychological Association, 2016). Simultaneously, a growing body of literature demonstrates differential treatment of older adults in psychotherapy (Kessler & Bowen, 2015, Kessler & Schneider, 2016, Mejia et al., 2018). The present study aimed to examine the prevalence of clinical bias toward older adults among clinical trainees and to explore …

Urban Green Space: Mitigator Or Multiplier Of Inequality In The Denver Metropolitan Area?, Joshua Charles Baldwin

Electronic Theses and Dissertations

Studies have shown that communities of color and low-income populations are likely to live in neighborhoods that lack access to quality green spaces, unable to directly benefit from the environmental, recreational, and cultural services they provide. The goal of this research was to determine if the green space inequality patterns seen globally and nationally exist in the Denver Metropolitan Area. Using an existing green space dataset, ecosystem services fieldwork, GIS digitizing, and bivariate correlation analysis I uncovered numerous green space inequalities based on proximity, acreage, and quality. Key findings included 1) Lakewood’s Hispanic and less-educated populations have relatively little access …

Impacted Youth: Why School Psychologists Need To Consider Diverse Approaches Of Support, L. Morgan Beidleman

Electronic Theses and Dissertations

This paper examines trends among youth who are highly impacted by multiple adverse experiences. It outlines potential patterns of risk and protective factors often experienced by this population and encourages school psychologists to recognize, consider, and advocate for the needs of these youth. It goes on to describe and interpret the cultural practices of Leadership Coffeehouse, a Denver-based social enterprise that seeks to support disconnected youth through professional development and hands-on learning. Finally, because of the unique training school psychologists receive, considerations for expanding the role into non-traditional educational settings are proposed.

Ayahuasca’S Religious Diaspora In The Wake Of The Doctrine Of Discovery, Roger K. Green

Electronic Theses and Dissertations

‘Ayahuasca’ is a plant mixture with a variety of recipes and localized names native to South America. Often, the woody ayahuasca vine (Banisteriopsis caapi) is combined with chacruna leaf (Psychotria viridis) in a tea, inducing psychedelic effects among its users. While social usage varies among Indigenous Peoples of South America, during the twentieth century new religious movements in Brazil began employing the mixture as religious sacrament. Additionally, various centers for ayahuasca “healing” have emerged both inside and outside of the Amazon Rainforest, frequently with the aim of helping people addicted to other substances. As interest grew, …

An Examination Of Relational Health, Belonging, And Self-Compassion In Chinese International Students, Elizabeth A. Harris Shaffner

Electronic Theses and Dissertations

Chinese international students (CISs), the largest segment of international students coming to the US to study at institutions of higher education (IIE, 2016), are reported to experience more acculturative stress than other international students because of the vast differences in social and cultural norms between the United States and China (Li & Glasser, 2005; Yeh & Inose, 2003). The present study used Relational-Cultural Theory (RCT) as the framework to explore the ways undergraduate CISs struggle and thrive in the face of acculturative stress and to understand how positive and negative outcomes are associated with their relational health, sense of campus …

Living Words; Dying Flesh: The Truth And Testimonies Of Desdemona In Othello And Pompilia In The Ring And The Book, Martha Clare Brinkman

Electronic Theses and Dissertations

This thesis explores the ways in which Desdemona in William Shakespeare’s Othello (1603/4) and Pompilia in Robert Browning’s The Ring and the Book (1868) exemplify female characters whose testimonies highlight their souls’ salvation and demonstrate that they ultimately transcend their domestic roles. This thesis engages historical scholars who discuss the tensions between the Roman Catholic and Anglican churches and the state in early modern and Victorian England, and literary scholars who focus on Desdemona and Pompilia as either submissive or possessing agency. This thesis includes the work of developmental psychologist, Carol Gilligan, to show how Desdemona and Pompilia emphasize care …

School Facet Through Surrounding Factors: A Geospatial Analysis Of Community Social Capital Impacting Elementary Schools, Sajjid Budhwani

Electronic Theses and Dissertations

School performance rating is an important factor which not only provides a quick snapshot of how the students are performing on various measurement indicators but also decides a school’s future course of actions, strategies, resources, and its existence. Despite its significant importance, the school performance framework does not consider where the schools are geographically located and the surrounding factors within which they operate. The researcher of this study presented a landscape of the surrounding factors and its impact on the elementary schools within Denver Public Schools district. In this study, the surrounding factors are geospatially analyzed to determine the extent …