Digital Commons Network^™

Irreversible Electroporation Potentiates Beta Glucan Induced Trained Innate Immunity: A Novel Combination Treatment For Pancreatic Adenocarcinoma., Matthew Woeste

Electronic Theses and Dissertations

Pancreatic cancer (PC) is a challenging diagnosis yet to benefit from advances in immune oncologic treatments. Irreversible electroporation, a non-thermal method of tumor ablation, is used in treatment of select patients with locally advanced unresectable PC and has potentiated the effect of certain immunotherapies. Yeast-derived particulate β-glucan induces trained innate immunity and successfully reduces murine PC tumor burden. This study tests the hypothesis that IRE may augment β-glucan-induced trained immunity in the treatment of PC. β-Glucan-trained pancreatic myeloid cells were evaluated ex vivo for trained responses and anti-tumor function after exposure to ablated and un-ablated tumor conditioned media. β-Glucan and …

Toward A Comprehensive Account Of Orientation Selectivity In The Retina., Megan Zipperer

Electronic Theses and Dissertations

Retinal Ganglion Cells (RGCs) form functionally distinct signaling channels that selectively encode features of the visual input including direction of motion, contrast polarity, size, and color. A highly conserved visual channel amongst vertebrates conveys orientation selectivity, i.e., the selective firing of neuronal cells in response to elongated stimuli along a preferred orientation. Orientation selectivity is an apparent critical computation and several studies have reported aspects of it, including cell type identity in anatomical reconstructions, and functional characterization of at least four different identified RGC types. But how cell types in the different studies relate is not well resolved; the mechanisms …

Microgenerations: Bridging The Generation Gap In Workplace Values., Melissa Kempf Taylor

Electronic Theses and Dissertations

Generational differences are a popular topic, and attention to them is heightened each time a new generational cohort comes of age. This trend continues with increasing interest in the Homelander generation that is now entering the workforce. Differences in values are often blamed for tensions in generationally diverse organizations. Past generational research has reported mixed results and acquired many critics. This study aimed to address common challenges with generational research and assist in distinguishing between truly valid and simply popular information. This study’s purpose was to identify differences in values between members of major generational cohorts and individuals in microgenerations …

Menstruation Stigma: A Qualitative Exploratory Study Of The Lived Experiences Of Nepali Women., Imisha Gurung

Electronic Theses and Dissertations

Despite the numerous challenges and barriers that menstruation taboos and stigma pose to the health and well-being of Nepali women and girls, this problem has received little attention in Nepal and has been under-researched. This study fills a critical gap in our understanding of the lived menstruation experience of Nepali women utilizing a qualitative descriptive approach in Kathmandu, Nepal. The data collection comprised in-depth, semi- structured interviews with 22 Nepali women. The findings provide various influencing socio- cultural factors at multiple levels of socioecological model that shapes the lived menstruation experiences of Nepali women and the impact on their mental, …

Impact Of Employee-Supervisor Attachment Styles On The Prevalence And Symptomatic Expression Of Secondary Traumatic Stress In Public Child Welfare Workers., Lisa Purdy

Electronic Theses and Dissertations

Child welfare organizations throughout the nation grapple with turnover rates estimated to be as high as 65% (e.g., CWLA, 2016; Edwards & Wideman, 2018). Turnover contributes negatively to client outcomes, organizational financial shortages, and to perpetuating stressful conditions for the child welfare workforce. One factor found to contribute to turnover within child welfare is that of secondary traumatic stress (STS). Child welfare workers are known to experience higher rates of STS than any other helping professional (Brady, 2017). However, while many risk and protective factors for secondary traumatic stress have been evaluated, there remains a gap in the literature as …

Our Story, Our Song: Assessing And Addressing Black Women's Healthcare Experiences., Jason Deakings

Electronic Theses and Dissertations

Despite advancements in medicine and health sciences, health disparities and declining life expectancy persists among Black women in the United States. Researchers and non-traditional healthcare providers suggest alternative healing (e.g., music and Sister Circles) and research methodologies to achieve a culturally conscious, traumainformed, quality, and holistic care and practice. The intersecting identities and cultural responsibility of Black women highly influences the barriers and facilitators on the uptake of healthcare services. Utilizing a community engaged research approach, this qualitative study assessed the healthcare experiences, as well as the role of music in the lived and retold experiences of Black women navigating …

Spirits In My Studio., Katelyn Gabbard

Electronic Theses and Dissertations

The exhibition “Spirits in My Studio” unveils the inventories of elements in human relationships and connections through collecting and transforming remnants left behind—admiration of an object combined with a presentation format that creates an immersive three-dimensional field to traverse. An acknowledgment and celebration of entropy, the exchange in human experiences elevates the process to both content and medium. Moreover, it creates active entanglements with genuine physical relationships with the artist, the making, and the audience.

Fear Of Becoming A Victim Of Crime On A College Campus: A Visual And Factorial Experimental Design Survey Analysis Of Location And Demographic Factors., Nancy Steinmetz

Electronic Theses and Dissertations

Vanessa LoBue (2013) states that the emotion of fear, “a signal of impending threat” (p. 38) is common among mammals. For over five decades, there has been substantial research into what in society, or our communities, makes us fearful. It is this author’s intention to examine how college students’ fear of crime or fear of victimization may be heightened or intensified by specific factors that are commonplace on college campuses and areas adjacent to those campuses. Nicole Rader (2004) argues that the fear of crime discourse needs to be expanded to a larger “construct” called “the threat of victimization” (p. …

Working For Yourself: A Guide For Performers With Learning Difference., Sa'id "Nxttime" Kelly

Electronic Theses and Dissertations

Working For Yourself a Guide For Performers with Learning Differences is a combination of advice and tips that are intended to help performers especially those living with learning differences. The thesis helps performers find ways to work with their true selves on stage as well as in preparation for a role. There is no final result to this process, just multiple ways to be more confident with the choice you’ll make while performing and preparing for a role.

Transmission And The Evolution Of Diseases Caused By Chlamydia Trachomatis, Sars-Cov-2, And Plasmodium Species., Nathan Steffens

Electronic Theses and Dissertations

Principles of natural selection have proven valuable for explaining why pathogens cause the diseases that they do. In theory, the evolved level of host exploitation should reflect how dependent a pathogen is on host health for transmission. This dependency is shaped by transmission mode and transmission opportunity, which should therefore be predictors of disease manifestations. In this dissertation, I apply these principles to investigations of depression in Chlamydia trachomatis and virulence of SARS-COV-2 and Plasmodium species. This dissertation has five chapters. In chapter I, I describe the theoretical foundation of my dissertation research. I also briefly introduce each study system. …

The Association Of Long Working Hours And The Use Of Prescription Sedatives Among U.S. Workers., Emmanuel Ezekekwu

Electronic Theses and Dissertations

BACKGROUND: Meeting the needs of a round-the-clock and globalized society has led to an increase in long working hours. This trend has been accompanied by a corresponding rise in sleep disorders and subsequent use of sedating medications. Overtime hours have been associated with adverse health outcomes such as cardiovascular diseases, symptoms of psychological distress, and health behaviors, including risky intake of alcohol and smoking. Hence, the main objectives of this three-paper dissertation were to examine the multi-faceted relationship between working hours, the use of prescription sleep aids, the onset of psychological distress, and the use of health care services. METHODS: …

Neonate Atlantic Sharpnose Shark (Rhizoprionodon Terraenovae) Relative Abundance And Body Condition In Two South Carolina Estuaries Varying In Urbanization, Rileigh E. Hawk

Electronic Theses and Dissertations

Urbanization near estuaries has been shown to affect the growth and survival of juvenile sharks using the system as a nursery. North Inlet and Murrells Inlet, South Carolina, are similarly-sized, tidally-dominated, bar-built estuaries with extensive Sporobolus-lined tidal creeks but differ in degree of human impact. Previously, Murrells Inlet was shown to have a lower abundance and diversity of large sharks than North Inlet and Atlantic Sharpnose Sharks (Rhizoprionodon terraenovae) were shown to use North Inlet as a primary nursery. To examine potential differences in neonate shark abundance and growth between a developed estuary, Murrells Inlet, and a protected estuary, North …

Disability Justice In Higher Education: The Lived Experiences Of Disabled White Women Disability Services Directors, Emily Gaspar

Electronic Theses and Dissertations

Eight disabled white women disability services directors shared their experiences working in disability services in higher education. The ten principles of disability justice provided the framework for this interpretative phenomenological analysis. Individual interviews were used to gain an understanding of the lived experiences of the participants with specific focus on disability identity of the professionals working in disability services and how their identities inform their campus experiences, along with how their intersectional identities inform their disability identity. Participants were found to experience ableism and oppression, a broad spectrum of relationships, disability solidarity, disability disclosure, identity hierarchy, disability management and coping …

Discipline, Disparity, And Diplomas: Suspension And Grade Retention In A Southeastern State, Sarah N. Kangarloo Crist

Electronic Theses and Dissertations

This study was designed to explore how race and gender impact student success in a southeastern state. A mixed-methods design was implemented so that the quantitative data could be further explained and explored using qualitative research. The quantitative analysis was conducted using a three-factor ANOVA to analyze the number of days a student misses due to suspension and the number of grade level retentions; race, gender, and the district a student attends were used as the independent variables in the analyses. Purposive sampling and the development of a script for the qualitative interviews followed the quantitative analyses. Interviews with administrators …

Moral Objections To Pornography: Does The Reason For Opposition Affect Consumption?, Grant Parker

Electronic Theses and Dissertations

Recent literature has suggested a link between self-described “problematic” pornography usage or pornography addiction and moral incongruence (Grubbs et al., 2022; Guidry et al., 2019). That is, when someone is morally opposed to pornography, they feel worse about their use of it. As of yet, however, no link has been established between specific reasons for objecting to pornography and their effects on consumption. Participants were 54 adults selected randomly using Amazon’s MTurk survey distribution platform. Respondents completed demographic questions and 6 scales measuring frequency of pornography use, objections to pornography, self-perceived problematic porn use, external and internal shame, God representations, …

Building Resilience: A Mixed Methods Exploration Of Head Start Teachers Coping During The Covid-19 Pandemic, Ehichoya Edokhamhen

Electronic Theses and Dissertations

The purpose of this study was to explore the resiliency of Head Start teachers during the COVID-19 pandemic. The study explored the role social support (as an external factor of resilience) and self-efficacy (as an internal factor of resilience) played in the resilience of Head Start teachers during the COVID-19 pandemic. This study employed a sequential explanatory mixed methods design involving two phases: a quantitative and a qualitative phase. Participants in this study were 99 teachers in rural eastern Tennessee and some rural parts of Virginia, North Carolina, and New Mexico, who were Head Start teachers during the COVID-19 pandemic. …

Teacher Instructional Strategies Impacting Rural, High-Poverty Student Academic Outcomes, Erin Kinney Burt

Electronic Theses and Dissertations

There is an abundant amount of interest among educators surrounding what actions can be taken by the government, local representatives, school boards, administrators, and teachers to assist rural, high-poverty students flourish academically. An uninspiring truth related to this subject is many times, a student receives the education the state and local communities are able to provide based on the quality of teachers they are able to retain and the resources available. Instructional strategies teachers implement could influence the quality of education students receive and could leave a community in a constant cycle of dependency and hardship. The purpose of this …

Building Comprehension: A Causal Comparative Study Of Factors Contributing To The Oral Reading Fluency Of First Graders, Kimberly Michelle Shaw

Electronic Theses and Dissertations

Teachers are charged with the task of reaching all students academically in hopes all students will become proficient readers by third grade. Oral reading fluency is a predictor in academic success since fluency reflects comprehension. Students often come to school unprepared in their earliest years due to a lack of opportunity and/or early literacy experiences, creating an achievement gap, a disparity in academic performance between groups of students. This study identifies the correlation between socioeconomic status, race, gender, and preschool enrollment and the oral reading fluency of first-grade readers as indicated by the Dynamic Indicators of Basic Early Literacy Skills …

Leadership Development In Education For Sustainable Development: Evaluation Of Higher Education Students In Sustainable Development Programs, Michelle Dzurenda

Electronic Theses and Dissertations

The United Nations Department of Economic and Social Affairs (UN DESA) has been working decades towards reaching Sustainable Development Goals (SDGs) to create peace and prosperity for people and the planet. The 2030 Agenda was created as an urgent call to action, a global partnership, and a comprehensive plan to work towards the 17 SDGs. For this study, the focus is on Goal 4- quality education and the impact of leadership on Education for Sustainable Development (ESD). Leadership on ESD has been a more recent topic and under researched. By making advancements in leadership on ESD there will be positive …

The Relationship Between Academic Self-Efficacy And Academic Achievement Of First-Time First-Year Students Enrolled At A Technical College, Heather Marie Hoppe

Electronic Theses and Dissertations

Student persistence, retention, and completion are continued concerns in higher education. While external influences contribute to persistence and retention, the focus of this research study was to determine the academic self-efficacy and self-regulated factors that influence the academic achievement of first-time first-year students who persist from the fall to spring semester at a Southeastern technical college. One hundred four first-time first-year students who persisted from fall 2021 to spring 2022 completed an Academic Self-Efficacy Survey. There were five significant predictors identified in the analysis. The three self-regulated learning tasks: “I can finish homework assignments by deadlines,” “I can organize my …

Teaching Students With A Mild Intellectual Disability How To Respond To Strangers Using Computer-Based Video Instruction, Chelsey Rae Simmons

Electronic Theses and Dissertations

Computer-based video instruction (CBVI) has been effective in teaching students with disabilities various health, community, and safety skills. Research suggests that CBVI is often used in conjunction with community-based instruction (CBI). Frequently, students with severe disabilities or students who are of high school age participate in CBI and/or CBVI and its accompanying research. This study investigated the effectiveness of CBVI to teach students with a mild ID, ages 11-13, appropriate responses to lures from strangers. A single-case, multiple probe across participants design was used to examine the impact of CBVI on one dependent variable, a correct two-step response (verbal and …

Student-Athlete Retention: An Analysis Of Student-Athlete Retention At A Small, Private, Highly Residential Ncaa Division Ii Institution In The Southeast, Malcolm Kendrick Reed

Electronic Theses and Dissertations

Retaining students in higher education is ever-changing, requiring continual evaluation and institutional commitment to ensure measures are implemented to meet the varying demands of today’s college students. Student-athletes make up a large percentage of the overall student population on many college campuses, thus, warranting further research to understand trends and factors that impact the retention of this key group of students. The purpose of this study was to examine the factors that contributed to the retention of student-athletes at a small, private, highly residential NCAA Division II institution in the Southeast.

The study focused on the experiences of student-athletes at …

Creating Unicorns: Teaching Iep Literacy And Accommodation Self-Advocacy Through Asynchronous Interactive Video Modules, Kathleen M. C. Dorr

Electronic Theses and Dissertations

Data indicate that individuals who disclose their disability status to self-advocate for accommodations at the postsecondary level may be as rare as the mythical unicorn. During the 2019–20 school year in the United States, 7.3 million public education students aged 3–21 years received some form of special education services. These students account for 14% of the nation’s public school enrollment (Irwin et al., 2021). In one study, only 20% of high school students reported having received any instruction on reading and understanding their own Individualized Education Program (IEP; Agran & Hughes, 2008). In another study, only 19% of postsecondary students …

Ableism, Ableist Microaggressions, And Psychological Thriving: A Mixed-Methods Study Of College Students With Physical Disabilities, Tonya Barnhill Dawsey

Electronic Theses and Dissertations

Microaggressions are daily insults to individuals that communicate messages of exclusion, inferiority, and abnormality. The term microaggression was originally used to explain the experiences of racial minorities. This term has also been used to explain the experiences of other individuals with oppressed identities. More recently, the term ableist microaggression has been used to describe these types of experiences for individuals with disabilities. Like other oppressed groups, individuals with disabilities experience ableism through interpersonal discrimination which is often delivered in a subtle, ambiguous, and unintentional manner that is difficult to address. Qualitative studies in the field of education and disability studies …

Workplace Factors That Contribute To Teacher Intent To Leave The Profession, Teresa Blount Gibbons

Electronic Theses and Dissertations

There is a nationwide shortage of qualified teachers, with 90% of all teacher shortages caused by teacher attrition (Carver-Thomas & Darling-Hammond, 2019). This study surveyed public school K-12 teachers in South Carolina to gain an understanding of workplace factors that contribute to teacher intentions to quit/ teacher attrition. The current design measures teacher stress perceptions of workplace factors as the relational theoretical lens to determine teacher intention to leave or likelihood of attrition. The results of a study suggest that student stressors and workload are the most important factors in teacher attrition. A qualitative analysis of student stressors found that …

Covid-19'S Impact On School Principals' Self-Efficacy As Managerial Leaders, Krystle Marie Ballatore

Electronic Theses and Dissertations

This dissertation in practice (DiP) employs qualitative research and educational theories to examine the impact of COVID-19 on school principals' self-efficacy in one South Carolina school district. Its theoretical framework is based on Bandura's (1977, 1986, 1997) social cognitive theory. The dissertation begins by outlining the specific problem at hand, relevant general concerns, and a purpose statement. This problem serves as the foundation for the research questions: How has the COVID-19 pandemic impacted principals' self-efficacy as their schools' managerial leaders? How do these principals' experiences vary in degree of impact by school level (i.e., early childhood, primary, elementary, intermediate, middle, …

Deterrent Effects Of The Select Magnetic And Repellent Treated (Smarttm) Hooks And The Recently Developed "Smarter" Hooks On Sharks In Recreational Hook-And-Line And Longline Trials, Ryan Lowndes

Electronic Theses and Dissertations

As bycatch continues to impact global shark populations, there is a continuing need for effective bycatch reduction devices. Prior research has shown promise in exploiting sharks' electrosensory ability to this end. We tested the deterrent efficacy of the Select Magnetic and Repellant Treated (SMARTTM) and the newly developed "SMARTER" hooks in experimental longline and hook-and-line trials. Both are magnetized and contain an electropositive metal component made of magnesium (SMART) and a magnesium alloy designed to extend longevity (SMARTER). We deployed 127 longlines with SMART hooks, SMARTER hooks, controls, and procedural controls from 2021-2022 in Winyah Bay, South Carolina, and caught …

The Post-Pandemic Influence On Social Emotional Learning In The K-12 Music Classroom, Jodie Michelle Rowe

Electronic Theses and Dissertations

The purpose of this research study was to understand the influence of the COVID-19 pandemic on the post-pandemic state of social emotional learning in music classrooms. This study addresses a vital need for an investigation into the current social emotional needs of students in music classes to then provide information on common practices for music teachers to utilize with their students to best meet these current needs in social emotional learning and communities of practice. The methodology utilized for this study was a qualitative narrative study approach, with focus groups serving as the main form of data collection. Results of …

How Marginalized Students Find Themselves Included In Syllabi: An Interpretative Phenomenological Analysis, Jean Kennedy Bennett

Electronic Theses and Dissertations

This dissertation presents the first known Interpretative Phenomenological Analysis (IPA) investigation of how marginalized students are included in syllabi. This study fills a gap in the literature due to the changing demographic of college students, the absence of faculty who share these marginalized identities, the syllabus being the first point of contact with students, and syllabi studies not including student voices. There were two research questions: how do marginalized students understand themselves as included in syllabi? and, how do marginalized students make meaning of their experiences with syllabi through their intersecting identities? This study used IPA to analyze each participant's …

Evaluating Clinical Educational Learning Outcomes For A Changing Field: Utilizing A 2:1 Collaborative Learning Model In An Acute Care Setting For First Semester Speech-Language Pathology Graduate Students, Lori-Ann Ferraro

Electronic Theses and Dissertations

Exploring clinical education models that may increase the number of clinical placements while improving learning outcomes is an important step in preparing competent entry-level speech-language pathologists. Placement shortages play an important role in the urgency of evaluating the efficacy of alternative clinical education models in SLP. The 2:1 collaborative learning model is a promising exemplar that has the potential to increase the number of clinical placements in practice settings twofold while simultaneously providing an excellent learning experience for students.

A retrospective, qualitative, descriptive, embedded case study design methodology was used. Recruitment was directed at both the first year SLP graduate …