Digital Commons Network^™

Epidural Stimulation For Urogenital Dysfunction In The Spinal Cord Injured Rat., Natasha Lorraine Wilkins

Electronic Theses and Dissertations

Spinal cord injury (SCI) is a devastating, life changing event that greatly impacts quality of life. SCI can have body-wide, multi-system consequences including dysfunction within the urogenital system. Challenges with the urinary system include urinary incontinence, urine retention, and detrusor-sphincter dyssynergia all of which require maintenance through the regular use of catheters. Sexual dysfunction in men, who comprise nearly 80% of the SCI population, includes erectile dysfunction, anejaculation, retrograde ejaculation, poor expulsive force during ejaculation, and poor sperm quality. The treatment for sexual function in SCI men is focused more on fertility through the collection of sperm for insemination procedures …

Associations Of Natural Vegetation In Relation To Colorectal Cancer Hotspots And Colorectal Cancer Survival., Johnnie Newton

Electronic Theses and Dissertations

Background: Across Kentucky, county-level geographic disparities in colorectal cancer (CRC) incidence and outcomes exist. Given the heterogeneity of lifestyle, socioeconomic (SES), and environmental factors within a county, more granular approaches should be used to identify local areas with a high CRC burden and identify the area-level factors that may contribute to geographic disparities. Studies reported that living in greener areas is associated with beneficial health outcomes, including lower mortality. Despite growing evidence that natural vegetation (greenness) exposure is associated with increased physical activity and obesity, two well-known CRC risk factors, epidemiological studies investigating the association of residential greenness exposure with …

Establishing A Mouse Model Of Cerebral/Cortical Visual Impairment., Dana K. Oakes

Electronic Theses and Dissertations

Cerebral/cortical visual impairment (CVI) is a disorder most often caused by perinatal hypoxic injury to the developing brain. CVI is the leading cause of childhood visual impairment in developed nations, encompassing deficits in many aspects of vision including visual acuity, contrast sensitivity, and object recognition. The pathophysiology of CVI is not well understood because no animal model currently exists to study this disorder. Because there is no animal model, the pathophysiology of CVI is poorly understood. Here, we developed a murine early postnatal hypoxic model of CVI by exposing mice to 9.5% O₂ at postnatal day (P)3 for a …

Housing Policy And Eviction: An Iterative Process., Oleksandra Maksymivna Belinova

Electronic Theses and Dissertations

Previously, eviction has been perceived as a legal problem rather than a social issue. Previous literature examines eviction as a social problem and the role of program administrators in policy implementation. Through a mixed-methods study of in-depth semi structured interviews and secondary descriptive analysis of eviction data, this study serves explores program administrators’ perspectives on housing policy and eviction practices and the impact these perspectives have on policy implementation and eviction prevention. The results indicate that program administrators view eviction as a legal phenomenon influenced by housing market dynamics with eviction prevention efforts limited by data collection and the lack …

Covid-19 Infection And Mortality, Patient Comorbidities, Social Determinants Of Health, And Environmental Influences In Kentucky., Shaminul Hoque Shakib

Electronic Theses and Dissertations

OBJECTIVES: To investigate patient- and county-level disparities in COVID-19-related mechanical ventilation use and mortality by SDOH factors and comorbidities among Medicaid non-pregnant adult beneficiaries in Kentucky. Additionally, to compare the association of COVID-19-related infections and mortality with social mobility and weather between Indiana and Kentucky during the stay-at-home period (March 1 to May 15, 2020). METHODS: In chapter 2, an administrative claims-based retrospective cohort study was conducted using the Kentucky Health Facility and Services database. Medicaid beneficiaries who were hospitalized during 2020–2021 in Kentucky were considered in the logistic regression and the Cox regression model to estimate the risk of …

Social Identity And Personhood At An Early Byzantine Cemetery: Late Antique Child Burials At Syedra, Turkiye., Mekenzie Riley Davis

Electronic Theses and Dissertations

Bioarchaeological studies of children in the past have proliferated in recent years and illustrate the informational depths accessible through investigations of mortality, age, and health and disease. Alongside analyses of childhood stress and mortality, the mortuary treatment of children provides critical insight into the social structures and identity formation processes that individuals or groups are subject to in life. This thesis will investigate the intersections of childhood, gender and sex, space, and mortuary treatment as seen in a Byzantine cemetery comprised primarily of children at the site of Syedra, Türkiye through bioarchaeological and proteomic analysis. Specifically, it seeks to explore …

Adaptive Robot Collaboration Using Robotic Skin And Motion Similarity., Jordan Dowdy

Electronic Theses and Dissertations

An essential part of robotics research is human-robot collaboration, which enables the use of current and new robots in everyday life and the workforce. This research applies to both parts of human-robot collaboration: physical human-robot interaction (pHRI), as well as non-physical human-robot interaction. The physical interaction uses tactile sensors and a Neuroadaptive Controller (NAC) to allow for the guidance of a robotic arm and its end-effector. The non-physical interaction uses a novel motion similarity metric, the Cartesian Segment Online Dynamic Time-Warping (SODTW), to allow a robot to better adapt to the speed of the user performing the motion during imitation …

Understanding Barriers To Effective And Equitable Covid-19 Response Through The Evaluation Of Essential Needs Program In Jefferson County, Ky., Haritha Pallam

Electronic Theses and Dissertations

This study utilized a multi-method study approach to assess the effectiveness of the Essential Needs Program (ENP), aimed at aiding priority groups in successfully completing isolation or quarantine (I/Q) during the COVID-19 pandemic. It commences with an overview of the COVID-19 pandemic's history and the role of ENP as a local emergency response strategy to mitigate community spread. Chaos and systems theories were employed to comprehensively understand disaster phenomena and factors influencing individual adoption of protective measures during the pandemic. Additionally, institutional decision-making models and implementation science were utilized to elucidate how public health stakeholders coordinated ENP services provision and …

Figure Worlds: An Analysis Of The Untold Stories Of Female Teachers Of Color., Anetria B. Swanson

Electronic Theses and Dissertations

This dissertation explores the lived experiences of Black female teachers in a large urban school district, focusing on how these experiences shape their identities, influence their professional practices, and affect their retention in the profession. Despite the growing recognition of the importance of teacher diversity, Black female teachers often encounter unique challenges, including systemic racism, microaggressions, and a lack of support and resources. Through a narrative inquiry approach, this study amplifies the voices of nine Black female teachers, uncovering their stories and the complexities of their professional lives. Guided by Critical Race Theory and the concept of figured worlds, this …

Examining Associations Between Parental Meta-Emotion, Child Adhd Symptoms, And Socioemotional Impairments., Meaghan Flynn

Electronic Theses and Dissertations

Children with elevated attention-deficit/hyperactivity disorder (ADHD) symptoms are at increased risk for social and emotional problems compared to typically developing peers. Emerging research has suggested targeting parental emotion socialization practices to enhance socioemotional development among this population. Interventions have explored how targeting specific emotion socialization behaviors may promote emotional and social functioning for youth with ADHD; however, little research has evaluated how underlying parental attitudes may influence these behaviors and outcomes. Parental meta-emotion philosophy (PMEP) refers to an organized set of thoughts and beliefs on how parents view the purpose of emotions, expression of emotions, and how these beliefs are …

Risk Perception, Diabetes Risk Knowledge, And Fatalism In Adults At Risk For Type 2 Diabetes: A Self-Determination Theory Perspective., Cassandra M. Gonzalez

Electronic Theses and Dissertations

Introduction: Rising rates of diabetes in the U.S. indicate an urgent need to explore and understand factors that elucidate individual diabetes risk. Research of fatalism, the belief that events are predetermined, suggests that fatalistic beliefs influence, shape, and potentially determine health behavior and decision-making. The Theory of Self-Determination posits the importance of motivation and competence in health behavior outcomes. The present study aimed to expand fatalism research by examining associations among fatalism and diabetes-related beliefs and knowledge, including perceived risk and risk knowledge, within the Self-Determination theoretical framework. Methods: Participants were 130 adults aged 26 to 64 without diabetes at …

Coproduction Revisited: From Theory To Practice., Brenton Clarke Hereford

Electronic Theses and Dissertations

Coproduction, or the interaction of citizens with their public service provider, has been used in policy responses to a myriad of service delivery problems, especially policing. This dissertation uses a three-manuscript approach to revisit coproduction both as a theory and a practice. The first manuscript tracks the evolution of coproduction as a theory from three different disciplines: economics, urban theory, and public administration. In addressing the three disciplines, the manuscript explains what broadly united the coproduction literature and the differences that hindered the early development of the concept. It concludes with how the concept is used today, and how future …

Enhancing The Anticancer Effects Of Apiaceae Spice Phytochemicals., Jared Lee Scott

Electronic Theses and Dissertations

Breast cancer (BC) is a leading contributor to the death of women and is the most common type of cancer. Many chemotherapy drugs are developed from plants, and some plant extracts can exhibit significant anticancer activities while also having less toxic side effects. The Apiaceae plant family consists of several species that are used as culinarily spices which have demonstrated antioxidant, chemopreventive, and anticancer activities. The encapsulation of anticancer phytochemicals into naturally produced membrane-bound nanoparticles known as exosomes could improve their systemic distribution and efficacy. Exosomes are involved in cell-to-cell communication through the delivery of proteins, nucleic acids, and small …

A Qualitative Narrative Study About Mental Well-Being And Coping Strategies In Generation-Z Undergraduate Student Leaders, Lacey Folsom

Electronic Theses and Dissertations

This study was a qualitative narrative on the advantages experienced by Generation Z students who participated in leadership roles within university-sponsored student organizations. This study incorporated generational, coping, and transactional theories to help the researcher establish a potential link between the mental well-being of students and their participation in cocurricular university-sponsored groups. The primary goal of this study was to gain a deeper understanding of how students perceived the influence of their participation in student organizations on their ability to handle mental well-being issues. It sought to explore whether factors such as time commitment, skill development, or an increased sense …

Effects Of Secondary Traumatic Stress And Burnout In Special Education Teachers, Alison Bradford M.A.

Electronic Theses and Dissertations

Secondary traumatic stress and burnout have been well-documented in the psychological field. In recent years, these effects of occupational stress have started appearing in other professions, especially in helping fields such as mental health, social work, and even education. The purpose of the study was to explore teachers’ perspectives about their current levels of stress, including burnout and secondary traumatic stress along with their current methods of managing stress to determine whether secondary traumatic stress predicts burnout and whether secondary traumatic stress affected special education teachers at a higher rate than general education teachers. A survey was used to gather …

Furthering Ascidian Taxonomy Using Molecular Biology, Nicholas Gulnick

Electronic Theses and Dissertations

Ascidians are our closest invertebrate relatives and comprise nearly 3,000 species separated into three orders: Aplousobranchia (most speciose), Stolidobranchia, and Phlebobranchia (least speciose). Ascidians can be classified as either solitary or colonial organisms. Species delimitation using morphological characters alone has had varied results. Well known, widely distributed, morphological species have turned out to be catch all species comprised of several cryptic species. Molecular markers can help mitigate some of the issues presented by strictly using morphological observations, including resolving the status of cryptic species, and accessing the expert knowledge required to identify a species. By incorporating molecular markers and pairing …

Variability In Nutrient Concentrations Across Regions Of The Winyah Bay River Plume, Anne Mackenzie Gossman

Electronic Theses and Dissertations

River plumes are one of the few large-scale features responsible for transporting particulates and terrigenous materials to coastal oceans. Macro-nutrients, such as dissolved inorganic nitrogen (DIN) and phosphorus (PO43-), are basic requirements for marine food webs. Due to the plumes’ ability to transport large quantities of these constituents, these systems contribute heavily to coastal productivity. This study focuses on the dynamics of the Winyah Bay river plume located in Georgetown, South Carolina. River plumes, including the Winyah Bay plume, are dynamic systems whose structures are comprised of a multitude of regions and features including the source, lift off, near-field, mid-field, …

College Students' Perceptions Of The Student-Teacher Relationship, Lauren E. Biggs

Electronic Theses and Dissertations

Humans, as social creatures, pursue relationships with others to fulfill various needs. As such, when we enter school, we naturally seek to establish relationships with teachers, who act as significant individuals in our lives. In general, research has shown that students with close, warm relationships with their teachers tend to experience more favorable outcomes related to academic achievement, behavior, and social-emotional factors. Students with more negative relationships with their teachers conversely tend to experience poorer outcomes. Though decades of research have consistently shown this correlation, few studies have examined the relationships between college students and their professors. The current study …

A Uniformly Most Powerful Test For The Mean Of A Beta Distribution, Richard Ntiamoah Kyei

Electronic Theses and Dissertations

The beta distribution is used in numerous real-world applications, including areas such as manufacturing (quality control) and analyzing patient outcomes in health care. It also plays a key role in statistical theory, including multivariate analysis of variance (MANOVA) and Bayesian statistics. It is a flexible distribution that can account for many different characteristics of real data. To our surprise, there has been very little work or discussion on performing statistical hypothesis testing for the mean when it is reasonable to assume that the population is beta distributed. Many analysts conduct traditional analyses using a t-test or nonparametric approach, try transformations, …

The Impact Of Perceived Administrative Support On Teacher Burnout, Madison L. Kelly

Electronic Theses and Dissertations

Teachers are crucial to many facets of life (Güneyli, 2012). Due to current occupational requirements and emotional demands, many educational professionals experience burnout (Roethler, 2021). Burnout occurs when daily occupational challenges overpower one's ability to maintain a healthy emotional state and meet professional demands (Roethler, 2021). Previous studies have been conducted on the levels of teacher stress and burnout (Agyapong et al., 2022; Chang, 2009; Lindqvist et al., 2021; Skaalvik & Skaalvik, 2021), while few studies explored the impact of administrative support and its contribution to burnout within the teacher population (Howard et al., 2017; Jacob, 2007; McCray-Davis, 2022; Tickle …

Avian Communities Monitored Along A Successional Chronosequence In Bottomland Hardwood Forests In The Lower Mississippi Alluvial Valley, Eamonn Alasdair Thurmond

Electronic Theses and Dissertations

Bottomland hardwood forests in the Lower Mississippi Alluvial Valley have been extensively reduced due to agriculture conversion and altered hydrology. Remnant forests have undergone further degradation from sources such as a lack of forest management, invasive species, and reduced regeneration of oaks (Quercus spp.). Recent restoration efforts of bottomland hardwood forests have focused on implementing wildlife forestry practices that prioritize restoring wildlife habitat while retaining profitable timber harvests. In this study I surveyed bird communities in bottomland hardwood forests in the Lower Mississippi Alluvial Valley along a successional chronosequence. Birds were sampled using automated recording units over 10 days …

An Exploration Of The Lived Experiences And Decision-Making Processes Of Alternative Education Teachers Using An Interpretive Phenomenological Analysis, Ashley Irene Zehner

Electronic Theses and Dissertations

Students with behavioral challenges and mental health concerns have unique academic, behavioral, and emotional needs. Due to high student to teacher ratio and lack of mental health and behavioral resources, some students may not have their needs met in a public school general education setting. An option that can be a better solution for these students due to lower student to teacher ratio, mental health resources, and behavioral support is schooling in alternative schools. This study explored the daily routines and the decision-making process of alternative educators as they work to meet the multifaceted needs of their students. Using an …

Manipulation Of Cellular Proliferating Cell Nuclear Antigen (Pcna) During Herpes Simplex Virus Type 1 Infection, Jessica Packard, Jill A. Dembowski

Electronic Theses and Dissertations

Herpes simplex virus type 1 (HSV-1) is a double stranded DNA virus that replicates within the nucleus of host cells. Using accelerated native isolation of proteins on nascent DNA (aniPOND), cellular proteins were found to associate with HSV-1 replication forks. One host factor of interest is proliferating cell nuclear antigen (PCNA), the DNA sliding clamp that tethers DNA polymerases and DNA damage response proteins to replicating cellular DNA. Although HSV-1 encodes its own DNA polymerase processivity factor (UL42), PCNA plays a key role in HSV-1 infection. We used commercially available PCNA inhibitors and short hairpin RNAs (shRNA) to investigate how …

Structure-Function Relationships In Neurodegenerative And Infectious Diseases: Biophysical Characterization Of Rna Secondary Structures By Computational Techniques, Kendy Guarinoni

Electronic Theses and Dissertations

The research described in this dissertation focuses on the investigation of the structure and dynamics of regions of RNA implicated in two diseases: COVID-19 and amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD). Both studies sought to create experimentally corroborated models that were used to characterize the structure and dynamics of the C9orf72 repeat expansion and the s2m region in coronaviruses, respectively and provided the foundation for future work. In our work involving the s2m region of SARS-CoV-2, the virus responsible for COVID-19, we determined that the homology modeling approach commonly used to derive atomistic structures when no coordinates are available yields a …

Environmental Factors (Rurality, Distribution Of Prescribers, And Altitude) Of People Who Died By Suicide In Montana, 2013- 2022, Anne N. Brown

Electronic Theses and Dissertations

Introduction: Suicide is increasingly prevalent in rural areas across the United States, especially in the western Rocky Mountain states. The connection between suicide and rural residency is not well understood, nor is the relationship between the distribution of prescribers, altitude, and suicide. Purpose: This retrospective quantitative study aimed to describe the characteristics of individuals who died by suicide in Montana and investigate the associations among rurality, distribution of prescribers, altitude, and suicide rate. Methods: Montana suicide mortality data for 2013-22 was used to describe individual characteristics. A second dataset was created for each Zip Code Tabulation Area (ZCTA) level in …

Navigating The Black Student First-Year Experience: Exploring Ways Peer Mentoring Can Enhance Engagement And Belonging At A Pwi, Richard V. Frazier Iii

Electronic Theses and Dissertations

Studies indicate that minoritized students attending Predominantly White Institutions (PWI) may struggle with engagement and establishing a sense of belonging. Peer mentoring may play a role in enhancing these opportunities to foster academic performance and retention. The sense of belonging and engagement for minoritized students at a PWI is essential to their academic sustainability. This qualitative narrative analysis study uses Strayhorn’s (2012) theory of college students’ sense of belonging as the theoretical framework to explore the peer mentoring experiences of 10 Black first-year students participating in a stand-alone model. Interviews were used to acquire insight into peer mentoring’s influence on …

Removing The Deficit Lens: Determining Support For Hispanic Newcomer Families In Public School Based On Their Unique Needs And Experiences, Shauna Schubiger

Electronic Theses and Dissertations

The purpose of this mixed methods study is to better understand the diverse needs of Latine newcomer families relocating to the United States and enrolling in a southeastern elementary school. Specifically, this study gathered and analyzed the unique experiences of these families immigrating into the U.S. to fully comprehend what they have been through to arrive here and how schools can help their families become involved in their children’s education. In K-12 education, there is a void which exists regarding who these families are and the need to humanize their journeys. This lack of research can be exacerbated by the …

A Descriptive Study: Aging In Place In The Rural Southeastern United States, Dama G. Cooley

Electronic Theses and Dissertations

Older Americans will soon outnumber children and younger adults. In 2022, there were 58 million older adults. By 2050, older adult numbers will grow to 82 million, and by 2060, 100 million. The National Institute on Aging calls for ongoing research on the impact that a historically large aging population will have on health, well-being, and quality of life. A key concern is how to meet needs while decreasing costs associated with institutional long-term care.

Most of these elders reside in the community and wish to live in their homes throughout their lives, but they will experience an increased need …

Emotionality Stigma Scale: Measurement Development, Reliability, And Validity., Hayley D. Seely

Electronic Theses and Dissertations

Emotions are biological responses to stimuli that allow individuals to derive meaning, appraise experiences, and prepare to respond. However, individuals perceive emotions differently based on emotion socialization which not only dictates the way emotions are viewed and managed but also has been directly linked with mental health outcomes. Furthermore, research shows emotion socialization is informed by demographic variables such as gender such that the expectations of emotionality differ; where women are taught to express emotions, men are taught to conceal. Given the societal rules regarding emotionality, it is possible that emotionality stigma – the stigma around the experience and expression …

From Surface To Subtext: Portrayals Of Success In Superfund Remediation., Haley Metcalf-Wade

Electronic Theses and Dissertations

Superfund sites represent some of the most contaminated and environmentally sensitive areas in the United States. How these sites are portrayed can significantly influence public perception of environmental risks, the effectiveness of remediation efforts, and the overall state of environmental health. Regulatory agencies like the Environmental Protection Agency (EPA) are entrusted with safeguarding public health and the environment. How they communicate about their actions, successes, and challenges directly impacts public trust and perceptions of their accountability. This dissertation examines the manifest and latent metrics used by the Environmental Protection Agency (EPA) to determine success in Superfund remediation by focusing on …