Digital Commons Network^™

Differential Expression Of Rna In The Rat Peripheral Nervous System Following Nerve Injury And Treatment With Pain-Relieving Celecoxib-Loaded Nanomedicine, Andrea Stevens

Electronic Theses and Dissertations

The neuroinflammatory response to peripheral nerve injury is associated with chronic pain and significant changes in the expression profiles of RNAs in neurons, glia and infiltrating immune cells: a neuro-immune triad. Chronic constriction injury (CCI) of the rat sciatic nerve provides an opportunity to mimic neuropathic injury and quantitatively assess behavior and differential gene expression in individual animals. Macrophages that phagocytose intravenously injected nanoemulsion carrying the non-steroidal anti-inflammatory, NSAID, Celecoxib, naturally accumulate at the site of injury resulting in relief of CCI behavioral hyper-sensitivity. It is not known beyond the inhibition of cyclooxygenase-2 (COX-2) activity and the reduction in prostaglandin …

Bacteria Analysis By Using A Supervised Machine Learning Algorithm Based On Droplet Microfluidics, Yulder Daniel Angarita

Electronic Theses and Dissertations

Sepsis is a major medical problem and massive resources have been invested in developing and evaluating alternative treatments. Statistics indicate that sepsis causes between one third and one half of all hospital deaths in the United States. Sepsis has a high impact on health care in the US, with direct sepsis costs in 2009 exceeding $15.4 billion. A research study found that a 1-hour delay in appropriate antimicrobial care resulted in a 7% - 10% rise in mortality. Several professional societies seek to reduce sepsis mortality by targeting the timely use of diagnostic tests and antimicrobial therapy. The diagnostic instruments …

Isolation, Structure Elucidation, And Synthesis Of Natural Products From Marine Cyanobacteria, Keren Solomon

Electronic Theses and Dissertations

This thesis describes the isolation, structure elucidation, and synthesis of natural products from marine cyanobacteria. A crude extract from a cyanobacterium collected in Curacao showed selective affinity for the dopamine D₅ receptor in a screen against a panel of CNS receptors. Due to the high similarity of the D₅ and D₁ receptor, to date there are no known ligands that differentiate them. Attempts to purify the compound responsible for this affinity led to the isolation of the known compound caylobolide A. A second extract from a cyanobacterium collected in Panama underwent bioassay-guided fractionation and yielded the novel …

The Influence Of Thomas Aquinas’ Concept Of Createdness On Josef Pieper’S Moral Philosophy, Sarah Slater

Electronic Theses and Dissertations

Josef Pieper’s practical moral philosophy can be best understood by reference to the theology of Thomas Aquinas, and specifically Aquinas’ concept of the created human person. Pieper uses Aquinas’ theological anthropology to argue for three actions which respond to the reality of being created: giving assent to having been brought into existence by God, perceiving God and created reality, and pursuing of the end of human life through the practice of the virtues in order to receive beatitude. Pieper’s well-known works on the seven virtues, on leisure, and on festivity rely on the same concepts from Aquinas which Pieper examines …

Without Words: Relational Neuropsychology And Creative Arts Therapies With People Managing Aphasia, Autumn Marie Chilcote

Electronic Theses and Dissertations

Aphasia describes the broad experience of disrupted language production or comprehension acquired after structural changes in the brain. These changes, usually associated with stroke, tumor, or cortical degeneration, are often co-occurring with other symptoms, such as emotional dysregulation, partial paralysis, and difficult social, occupational, and community relationships. Common approaches to research and rehabilitation with persons managing aphasia highlight conversation and semantic retrieval, with a lack in literature considering the diversity of symptoms and responses. Questions arise as to the ways that psychotherapies, typically language- centered, can be adapted to collaborative, low-verbal approaches that attend to the range of individual symptoms …

Protecting Healthcare Workers From Violence, Terry L. Taylor

Electronic Theses and Dissertations

Growing violence in the community increases the risks of injuries to healthcare workers. This project assessed the levels of emotional exhaustion, depersonalization, and acknowledgment of professional accomplishments in healthcare workers in the community who were responsible for the care of confused and combative clients. The community healthcare workers were assessed using the Maslach Burnout Inventory-Human Services Survey-Medical Personnel. An intervention was then presented, which focused on self-awareness, including mood assessments, soothing rhythmic breathing, compassionate focused imagery, and the creation of a safe place to process criticism compassionately. The participants were resurveyed after 30 days by repeating the Maslach Burnout Inventory-Human …

A Study Of The United States Influence On German Eugenics., Cameron Williams

Electronic Theses and Dissertations

This thesis is a study of the influence and effects that the United States had upon Germany from the rise of eugenics to its fall following the end of World War II. There are three stages to this study. First, I examine the rise of eugenics in the United States from its inception to the end of World War I and the influence it had upon Germany. Then I examine the interwar era along with the popularization of eugenics within both countries before concluding with the Second World War and post war era.

My thesis focuses on both the active …

A Case Study Of Civil War Environmental And Medical History Through The Disease Seasoning Of The 58th North Carolina Infantry Regiment In East Tennessee, Ashlie Richard

Electronic Theses and Dissertations

This thesis is a case study aimed at a key argument in the emerging field of Civil War medical and environmental history. While historians have long acknowledged disease as a major killer during the Civil War, only recently have environmental and medical historians turned their collective attentions to unpacking the complex interconnections of disease, environmental conditions, and culture. By examining the 58^th North Carolina Infantry Regiment from the mountains of western North Carolina, this thesis asserts that the combined role of the disease environment and conditions in military camps created the massive outbreaks of disease that characterized the seasoning …

The Lived Experiences Of Adolescent Ell Students In East Tennessee, Sarah Mould

Electronic Theses and Dissertations

Adolescent immigrant students face many challenges upon entering public schools for the first time, especially in rural areas where schools may not have the resources and cultural competence to meet their needs. Background factors like culture, previous schooling, and socioeconomic status combine with contextual factors in the learning environment, which further affect their academic outcome. The qualitative tradition of phenomenology was used to explore and describe the experiences and challenges of thirteen Spanish-speaking immigrant or newcomer youth who entered East Tennessee public middle or high schools within the last fifteen school years.

The findings indicated that parents’ perspectives and understanding …

The Effects Of Different Set Configurations On Concentric Velocities In The Barbell Back Squat, Hanson Wong

Electronic Theses and Dissertations

The purpose of this study was to determine if concentric velocities of lighter loads of could be augmented if they are performed heavier working sets. Twelve trained males with experience in the barbell back squat performed a 5RM and completed two separate squat training session conditions that consisted of three sets of five repetitions with 85% of their 5RM. Both conditions differed in the placement of a reduced-load set that was either performed after the working sets or during the warm-up period. No significant differences were observed in the working set MCVs in both conditions. Additionally, no significant differences were …

Act Scores And High School Cumulative Grade Point Average As Indicators Of College Graduation At One High School In East Tennessee, Ariane Day

Electronic Theses and Dissertations

The purpose of this quantitative study was to see if there was a significant difference in the mean American College Test (ACT) scores and high school grade point average (HSGPA) between students who attained a bachelor’s degree within 6 years of starting college and those who did not attain a bachelor’s degree within 6 years of starting college. Data from 2005-2013 high school graduates from one high school with only academic course choices were used. A series of independent t-tests were used to compare the mean ACT scores and HSGPA of students from both groups.

The goal was to find …

Advanced Placement And Dual Enrollment Courses For Economically Disadvantaged Students And 2-Year Completion Rates At Tennessee Public Higher Education Institutions, Mia Hyde

Electronic Theses and Dissertations

The purpose of this study was to measure the possible relationship between Advanced Placement and dual enrollment courses for economically disadvantaged students on 2-year completion rates at public Tennessee higher education institutions. A quantitative, quasi experimental, comparative design was used to analyze secondary data to determine if there is a relationship between Advanced Placement, dual enrollment courses, and 2-year completion rates for students in Tennessee community colleges and public universities. The sample for this study consisted of students who entered a Tennessee community college or Tennessee public university in the Fall of 2015. These students had taken at least one …

Pentecostal Women And Religious Reformation In The Progressive Era: The Political Novelty Of Women’S Religious And Organizational Leadership, Sherry Kaye Ms.

Electronic Theses and Dissertations

The Progressive Era in America from 1870 to 1920 introduced unprecedented change in the way Americans lived, worked, and thought about themselves in relation to the rest of the world. New platforms of charitable benevolence, religious activism, and legislative reform were enacted to meet the changed demographic landscape initiated by waves of new immigration from Europe. The tenor of religious worship shifted in mainstream and evangelical churches to reflect not only new ways of response to these changes, but new ideas of women as authoritative leaders in secular and religious institutions. Charismatic evangelical women influenced by an era of change …

Thwarted Interpersonal Needs, Depression, And Sleep Disturbances In Primary Care: Does Gratitude Help You Sleep?, Heather R. Altier

Electronic Theses and Dissertations

Sleep disturbances are prevalent in primary care patients and can be exacerbated by interpersonal dysfunction and depression. As well, thwarted interpersonal needs (TIN), including thwarted belongingness and perceived burdensomeness, contribute to depression. However, the presence of gratitude, a cognitive-emotional protective factor, may improve symptoms. We longitudinally examined the mediating role of depressive symptoms on the relation between TIN and sleep disturbances, and the moderating role of gratitude on the TIN-sleep disturbances and depression-sleep disturbances linkages. Our primary care patient sample (N = 223) completed self-report surveys at baseline (T1) and at a one-year follow-up (T2; n = 97). Patients …

Examining The Warm Handoff In Rural Integrated Care, Jamie Tedder

Electronic Theses and Dissertations

An ever-growing body of evidence supports the efficacy of integrated care as a treatment approach; however, less is known about what specific components of integrated care are most effective. This is especially true of warm handoffs, which are an often discussed but understudied process in integrated care. A total of 246 patient charts were reviewed to determine if type of referral (warm handoff or traditional) increased the likelihood of follow-up with behavioral health services as well as factors that might impact this relationship. There were no significant differences between type of referral and likelihood of follow-up with behavioral health services. …

Incarceration Experiences Of Older African American Adults Living With Hiv - A Constructivist Grounded Theory Study., Verena Schmidt

Electronic Theses and Dissertations

Two epidemics disproportionally impact older (50 years and over) African Americans compared to the general U.S. population: Incarceration and HIV/AIDS. Those aged 50 and older constitute the fastest growing age group of persons who are incarcerated in the United States. It is estimated that by the year 2030 about one third of the incarcerated population in the U.S. will be aged 55 years and older. While areas of “Incarceration, racial disparities and HIV” as well as “Aging and HIV” have been well studied and discussed in the literature, little is known about the lived incarceration experiences of African American persons …

Causal Comparative Study: The Effect Of School Scheduling And Academic Outcomes Of Economically Disadvantaged Students, Marcus D. Brannon

Electronic Theses and Dissertations

This study was designed to investigate if a statistical variance exists between traditional and A/B block school scheduling, and the effect on economically disadvantaged student achievement on the English I and Algebra I End-of-Course STAAR state-mandated exam, from 2015-2018. In response to studies illuminating the achievement gap, educational leaders in Texas implemented block scheduling in order to improve student outcomes among high school students. However, to date, published research studies yield mixed results of the effectiveness block scheduling has made on student achievement. The findings are expected to help to fill the gap in published literature, which focuses on the …

Examining The Relationship Among Middle School Students’ Performance On The Tnready Assessment, District Checkpoints, And Teacher-Assigned Grades, Kristina Dempsey

Electronic Theses and Dissertations

The purpose of this nonexperimental, quantitative study was to determine if there is a significant correlation among teacher-assigned grades (TAG), district checkpoint scores (CP), and student scale-scores on TNReady tests. The focus was on 1,445 seventh and eighth grade students who were enrolled at a middle school in northeast Tennessee during the academic years of 2017-2018 and 2018-2019, specifically for the content areas of English Language Arts and mathematics. The second purpose of this study was to examine any moderating effects of the categorical variable, students with disabilities (SWD) status, on the correlations among the district and state assessments and …

Gender Differences At The Highest Levels Of Mathematics Achievement: A Texas Based Study, Susanna Campbell

Electronic Theses and Dissertations

The purpose of this ex post facto study was to determine if gender differences exist in the top quartile of mathematics achievement in Texas as measured by STAAR. Performance data for 6,358,500 Texas students on the mathematics STAAR in grades 3-6 for the years 2016-2019 were examined in this quantitative study. The percentage of male and female students scoring in three different score bands, the 75^th-89^th percentile, the 90^th-95^th percentile, and the 95^th-100^th percentile, were presented. The Chi-square was utilized to determine if any difference in the percentage of male and …

The Economics Of Love, Débora Silva Viana

Electronic Theses and Dissertations

In this thesis I argue that the obligation to love based on the Christian tradition requires Christians to disperse their resources in a way that significantly evens out wealth distribution and increases social justice. Christians disagree on the terminology and some tenets of the goal of the Christian life (e.g., deification, beatific vision, communion with God, salvation). However, the requirement to practice love is common to all of these concepts, thus making love normative for Christians. I argue that when love takes such a prominent role in one’s life, then it naturally influences how one manages one’s resources. If love …

A Needs Assessment: Exploring The Unknown Needs Of The Homeless Unaccompanied Youth Within A West Texas Independent School District, Amy Grace Weiss

Electronic Theses and Dissertations

ABSTRACT This exploratory study aims to explore the unknown needs among the unaccompanied youth population within a small urban community in West Texas. This cross-sectional study surveyed a convenience sample of 10 unaccompanied youth attending school within an independent school district. Data were collected using a social worker’s case load during the spring semester of 2020, during the COVID-19 global pandemic. Findings showed a certain level of need within this community, such as emergency shelters and further research on food insecurity for this population. This implies the need for practice and policy on multiple levels to help this population who …

Connecting Right-Wing Authoritarianism To Environmental Beliefs And Behaviors: A Pilot Study., Rebecca Halpryn

Electronic Theses and Dissertations

Climate change is an urgent situation that may be alleviated by a dramatic transformation in individual’s lifestyles. Right-wing authoritarianism relates to a wide variety of beliefs and behaviors, yet little is known about its relationship with environmental beliefs and behaviors. An online survey utilizing the 18-item ACT scale, the revised NEP scale, the PEB scale, and background questions as conducted; 60 college students enrolled in introductory sociology courses responded. Multiple regression and backwards stepwise statistical methods were employed on the survey data to investigate the relationship between right-wing authoritarianism and pro-environmental beliefs and the relationship between right-wing authoritarianism and pro-environmental …

Fatalism As A Cultural Influence On Correlates Of Anxiety And Worry In Latino/A Adolescents., Judy Mier-Chairez

Electronic Theses and Dissertations

Evidence that Latino/as in the United States experience lower rates of anxiety disorders as compared to the non-Latino/a White population has not yet led to the identification of the sources of these differences. Higher rates of anxiety disorders among more acculturated Latino/a individuals compared to those lower in acculturation suggest there are influential cultural variables relevant to anxiety, specifically that there is a loss of a protective Latino/a cultural factor in the acculturation process. Fatalism, an often-cited Latino/a cultural characteristic, emerges as an intriguing candidate for exploration in relation to anxiety due to the shared elements of future orientation and …

Getting Up: An Ethnography Of Hip Hop Graffiti Writers, Their Art, And Perceptions Of Society's Reactions., Theodore Malone

Electronic Theses and Dissertations

This ethnographic analysis of the modern hip hop graffiti writing subculture connects the separate but complementary theoretical constructs of serious leisure (Stebbins 1982), dark leisure (Smith and Raymen 2016), recreational specialization theory (Bryan 1977), and edgework (Lyng 1990) and situates the writer “standpoint” (Smith 1987) in terms of interrelations of policy and written discourse. Past research found that writers were motivated by fame and status, to express artistic skills, and to control and destroy space (Brewer and Miller 1990). Others found that writers sought to express contestant notions of style and resist economic and political authority (Ferrell 1996; 2006), and …

Trust In Primary Care Providers: Perspectives From Deaf People., Greir Ander Huck Flynn

Electronic Theses and Dissertations

Trust is an integral part of the patient-provider relationship, responsible for influencing several key aspects of healthcare behaviors and patient perceptions of health outcomes. Though the topic has previously been discussed by scholars, little evidence exists to support the application of our understanding of trust in culturally Deaf populations. As such, this dissertation seeks to lay the necessary groundwork for further investigations on the topic by first understanding the nature of trust in patient-provider relationships from the perspectives of culturally Deaf people. The dissertation is comprised of five chapters. The first chapter provides an introduction to salient terms and concepts …

Making Modality: Transmodal Composing In A Digital Media Studio., Chris Scheidler

Electronic Theses and Dissertations

The multiple media that exist for communication have historically been theorized as possessing different available means for persuasion and meaning-making. The exigence of these means has been the object of theoretical debate that ranges from cultural studies, language studies, semiology, and philosophies of the mind. This dissertation contributes to such debates by sharing the results of an ethnographically informed study of multimedia composing in a digital media studio. Drawing from Cultural Historical Activity Theory and theories of enactive perception, I analyze the organizational and infrastructural design of a media studio as well as the activity of composer/designers working in said …

The Nigerian-American Immigration Experience: Overcoming Adversity Through Resilence., K. Chinwe Idigo

Electronic Theses and Dissertations

Nigerian-Americans are a fast-growing population in the United States, when compared to other immigrant groups. Despite growing numbers there is limited empirical research examining pathways that facilitate success among this immigrant population. This study addresses the dearth in literature by proposing and testing a modified ABCX model of family resilience among Nigerian-Americans. It is hypothesized that similar to other immigrant, and racial/ethnic minority groups in the United States, NigerianAmericans employ protective factors such as ethnic identity and resilience to buffer the effects of acculturative stress and perceived discrimination on well-being and psychological distress. Regression analyses suggest some consistency with the …

Practicing Pan-Africanism: West Indians And Governance In Kwame Nkrumah's Ghana., Nicholas C. Mcleod

Electronic Theses and Dissertations

After gaining independence from England, Kwame Nkrumah, the first President of Ghana, was transparent in his embrace of the entire African diaspora and actively recruited a number of Pan-African West Indian intellectual-activists, who mentored and advised him as a student in London, to help build Ghana as a Pan-Africanist state. Among these West Indian intellectual-activists were George Padmore, W. Arthur Lewis, T. Ras Makonnen, and Jan Carew. For these West Indians the appeal of Ghana was neither symbolic nor ceremonial, but rather an opportunity to achieve the ultimate objective of the Pan-African movement, a free and self-governed African continent. In …

Women Of Pop., Jourdan Cunningham

Electronic Theses and Dissertations

The hegemonic values that were represented in 1960s mass media were heavily reinforced by the Pop Art movement. Male Pop artists have often been viewed as genius, while the women were pushed aside to reside within the margins of the Pop canon. This thesis emphasizes the work of four female artists who participated in the Pop Art movement and were largely overlooked throughout Pop’s discourse. By analyzing their “popness” and Feminist viewpoints, it allows for the imbalance that has resulted from women Pop artists neglect throughout Pop’s discourse to be readdressed. In the Introduction I analyze the background of the …

Identifying Competencies And Outputs Of Sss Role In Stem Bridge Programs In The Silicon Valley, Alexandra C. Duran

Electronic Theses and Dissertations

This study identified the competencies and outputs associated with the role of student support specialists (SSS) in science, technology, engineering, or mathematics (STEM) bridge programs in the community colleges of Silicon Valley. The growth of STEM education, coupled with the increasing diversity of student population in community colleges, has made the work of SSS professionals in the region challenging. While the SSS professionals are often positioned as comprehensive, nonacademic support for STEM students, not enough has been documented on the competencies and outputs associated with SSS role in STEM bridge programs. In addition, most studies on student affairs professionals primarily …