Digital Commons Network^™

Metabolic-Epigenetic Regulation Of Macrophage Polarization., Jordan T. Noe

Electronic Theses and Dissertations

Tumor-associated macrophages polarized to an M2 phenotype (M2-TAMs) promote neo-angiogenesis, tumor-stromal matrix remodeling, and immuno-evasion, which, collectively, contribute to immunotherapeutic resistance and reduced cancer patient survival. Highly glycolytic “Warburg” cancer cells produce lactate that independently drives naïve M0→immunosuppressive M2 (M0→M2) macrophage polarization, but the mechanisms have not been fully elucidated. The atypical cytokine macrophage migration inhibitory factor (MIF) is a fundamental underlying requirement for immunosuppressive M2 macrophage polarization. Still, it is unknown whether a molecular link exists between lactate-supported and MIF-dependent M2 macrophage polarization. Using a combination of gene expression assays, chromatin immunoprecipitation, and metabolomic analyses, we identified that M2 …

The Effect Of Parent Interactions On Young Infants’ Visual Attention In An Object Manipulation Task., Nonah Marie Olesen

Electronic Theses and Dissertations

The Sticky Mittens (SM) task, an object-manipulation task that facilitates typically developing pre-reaching infants’ learning through active experience with objects, is often utilized to understand how experience affects young infants’ learning about objects. SM experience has been shown to increase infants’ attention to objects, object engagement, and object exploration (Libertus & Needham, 2010; Needham, Barrett, & Peterman, 2002) and facilitates development of causal perception (Rakison & Krogh, 2012; Holt, 2016). Although the majority of SM studies have involved parents interacting naturally with their infants, few have focused on how those interactions affect infants’ learning and performance during or after SM. …

Exploring Opportunities For Prevention Of Child Sexual Abuse In A Diverse American Muslim Community., Rishtya Meena Kakar

Electronic Theses and Dissertations

Recognizing the significant mental, emotional, developmental and health consequences for victims of child sexual abuse (CSA) and sociopolitical consequences for families and communities in every cultural, ethnic, and religious group around the world, this study sought to determine key opportunities for prevention of CSA in a diverse American Muslim community using a public health socioecological lens, rooted in aspects of critical theory. While there is considerable research on situational and individual-level risk factors related to CSA cases, there is less research on the societal and community-level processes related to the primary prevention of CSA, especially among minoritized communities. Responding to …

Variable Autonomy Assignment Algorithms For Human-Robot Interactions., Christopher Kevin Robinson

Electronic Theses and Dissertations

As robotic agents become increasingly present in human environments, task completion rates during human-robot interaction has grown into an increasingly important topic of research. Safe collaborative robots executing tasks under human supervision often augment their perception and planning capabilities through traded or shared control schemes. However, such systems are often proscribed only at the most abstract level, with the meticulous details of implementation left to the designer's prerogative. Without a rigorous structure for implementing controls, the work of design is frequently left to ad hoc mechanism with only bespoke guarantees of systematic efficacy, if any such proof is forthcoming at …

Motion And Emotion Estimation For Robotic Autism Intervention., Jacob M Berdichevsky

Electronic Theses and Dissertations

Robots have recently emerged as a novel approach to treating autism spectrum disorder (ASD). A robot can be programmed to interact with children with ASD in order to reinforce positive social skills in a non-threatening environment. In prior work, robots were employed in interaction sessions with ASD children, but their sensory and learning abilities were limited, while a human therapist was heavily involved in “puppeteering” the robot. The objective of this work is to create the next-generation autism robot that includes several new interactive and decision-making capabilities that are not found in prior technology. Two of the main features that …

Passive Method For 3d Reconstruction Of Human Jaw: Theory And Application., Mohamad Ghanoum

Electronic Theses and Dissertations

Oral dental applications based on visual data pose various challenges. There are problems with lighting (effect of saliva, tooth dis-colorization, gum texture, and other sources of specularity) and motion (even inevitable slight motions of the upper/ lower jaw may lead to errors far beyond the desired tolerance of sub-millimeter accuracy). Nowadays, the dental CAM systems have become more compromised and accurate to obtain the geometric data of the jaw from the active sensor (laser scanner). However, they have not met the expectations and the needs of dental professionals in many ways. The probes in these systems are bulky { even …

Git (Gender-Informed Trauma) In Black N Blue Boys / Broken Men: How Concepts Of Gender Restrict The Black Male Actor’S Creative Process And The Methods He Can Use For Creative Freedom., Tyler Tate

Electronic Theses and Dissertations

This study examines how the black male actor’s creative process can be affected by historical and cultural constructions of masculinity connected to race, sexuality, and physical movement. My research on black men’s experience with gender identity finds that social and cultural forces lead black men to reproduce behaviors that mirror a prescribed masculine ideal through physical movement. This prescribed masculine behavior is typically coded in terms of stiffness or lack of expression. This study explores how self-imposed restrictions reiterated by social standards of masculine behavior limit the creative freedom in the black male actor’s creative process. Specifically, black male actors’ …

Aggregation Dynamics Of Bulk Nanoparticle Haloing Systems And The Influence Of Non-Ambient Temperatures., Marzieh Moradi

Electronic Theses and Dissertations

One of the methods of assembling colloids into 3D crystal structures is through the use of nanoparticle haloing. Nanoparticle haloing is a stabilization mechanism in binary particle suspensions possessing both a size and charge asymmetry, with which the nanoparticles aid in the bulk suspension’s stability. By altering the volume fractions of nanoparticles, it is possible to control the effective repulsion between the microparticles. Understanding the colloidal interactions and aggregate crystallinity as a function of nanoparticle concentration, temperature, and time are key challenges in developing future materials and designing crystalized 3D colloidal systems. In this study, we investigated the effect of …

Refinement And Automation Using Algorithmic Control Of Breathforce, A Respiratory Training System For Patients With Spinal Cord Injuries., Anna Goestenkors

Electronic Theses and Dissertations

Spinal cord injuries (SCI) can lead to impaired respiratory and cardiovascular function and a general decrease in lung compliance. This can complicate breathing as well as impair the ability to sigh, cough, and clear secretions, leading to increased risk of respiratory infections. Respiratory training has been shown to combat these effects. BreathForce is under active development to create a user-centric inspiratory-expiratory device that is an affordable option for at-home training. This study reports on the refinement of valve design and automation incorporated into BreathForce to enhance and enforce clinical practices and processes as part of the respiratory training protocol used …

Exploring Meerwein-Ponndorf-Verley Reactions Using Metal Organic Framework Catalysts., Yuehan Zhou

Electronic Theses and Dissertations

The Meerwein–Ponndorf–Verley (MPV) reaction is a reaction that is used to reduce aldehydes and ketones to the corresponding alcohols with the added use of catalysts. The common metal triflate catalysts used in MPV reduction incur tremendous environmental hazards and high operational costs. The use of Metal-Organic Frameworks (MOFs) as catalysts can be an alternative due to MOFs’ extraordinarily high surface areas, ultrahigh porosities, tunable pore sizes, modifiable internal surfaces, and numerous framework structures. Moreover, using MOFs as catalysts for MPV hydrogenation is economically viable due to low operational and material costs. This study involves using MOF-808 (Hf) in the MPV …

Room Temperature Alkali Treatment Of Rice Straw For Enhanced Enzymatic Hydrolysis., Seth Mains

Electronic Theses and Dissertations

Due to the pollution of fossil fuels due to greenhouse emissions, researchers continue to search for alternative methods that allow for the clean production of energy, fuels, and polymer fibers. A method currently under investigation is the use of lignocellulosic biomass as a solution to current problems with energy and polymer fiber production. Through the process of pretreatment, possibilities for lignocellulosic biomass expand due to improved accessibility of the cellulose and hemicellulose which can be broken down via enzymatic hydrolysis into C5 and C6 sugars such as xylose and glucose. This study investigated the fermentation of the rice straw into …

Electrical Characterization Of Phytoplankton Suspensions Using Impedance Spectroscopy., Margaret R Jett

Electronic Theses and Dissertations

Phytoplankton are closely monitored because of their important environmental role, and the impacts they have on their local ecosystems. Some phytoplankton respond to stress by producing lipids, which can be harvested for biofuels and other chemicals. Microfluidic devices have been important in improving the portability and throughput of phytoplankton characterization methods, increasing their potential for in situ use. This study utilized a small sample of phytoplankton suspended in a stagnant medium and measured the impedance response using a lab-on-chip and impedance analyzer. The individual cell characteristics were derived from the impedance response of the group. The goal was to characterize …

Conversion Of Multicellds Digital Snapshots To Isa-Tab Format., Corey P. Chitwood

Electronic Theses and Dissertations

The MultiCellular Data Standard (MultiCellDS) is an interdisciplinary effort to create a data standard for sharing multicellular experimental, simulation, and clinical data. The ultimate goal of the overall project is to allow for data sharing that will lead to better analyses and simulations for multicellular biology and predictive medicine in association with the PhysiCell, a software that allows for simulations of large numbers of cells in 3D tissues. Digital cell lines are files that contain a standardized representation of a biological cell line and include phenotypic parameters as well as microenvironmental conditions for use in simulations. A Digital Cell Line …

The Influence Of Incubation Conditions On Oxygen Consumption During The Development Of Pantherophis Guttatus, Celeste Gallardo

Electronic Theses and Dissertations

The flexible shell of some oviparous reptiles has led to differences in nutrient mobilization and water relations when compared to their rigid-shelled counterparts. Flexible-shelled eggs gain more water during development, and because of the shell structure, yolk calcium content is higher than that of eggshells. When water availability is altered for reptiles with flexible-shelled eggs, differences in both energy and nutrient utilization are observed. This study was designed to determine the baseline metabolic rate during development for the snake, Pantherophis guttatus under normal conditions, and to observe how changes in eggshell calcium and water availability impact embryonic oxygen consumption. Eggshell …

Implementing Of Phase Potentiation Program With College Triathletes, David Fish

Electronic Theses and Dissertations

The purpose of this study is to determine the effectiveness of an in-season resistance training program on improving measures of strength in female collegiate triathletes. Nine females (age = 19.2 ± 1.1 years, height = 166.5 ± 12.5 cm, body mass = 61.1 ± 9 kg) with limited resistance training experience were examined for this study. Formal RT intervention was monitored for 7 weeks with the athletes being assigned 6 weeks of independent RT prior to the pre-test. Athletes completed a standardized athlete monitoring program pre and post resistance training intervention. Paired sample t-tests were used to determine differences …

Educator And Administrator Perceptions Of Sheltered Instruction In Stem Courses, Tommy D. Duncan Ii

Electronic Theses and Dissertations

The purpose of this qualitative case study was to explore the perceptions held by educators and administrators regarding sheltered instruction of English Language Learners (ELLs) in science, technology, engineering, and mathematics (STEM) classrooms; relevant professional development; and the use of the English Language Proficiency Standards (ELPS) within lesson plans. ELLs represent a subpopulation of students with significant achievement gaps in STEM, ultimately affecting student engagement and career interest in STEM. Ten STEM teachers and two administrators from a midsized middle school in west Texas participated in the study. Online semistructured one-on-one interviews and document analysis of submitted lesson plans from …

Student Perceptions Of The Effects Of The Modern Educational Reform Movement On The Concept Of The Whole Child, Edward Theodore Knight

Electronic Theses and Dissertations

As a robust public education system is critical to the future of the U.S. democracy, efforts to improve or reform education have been prominent since its inception. Unfortunately, recent strategies to improve academic achievement have not been successful, and unintended consequences were noted for both students and staff. A specific issue related to modern reform was the construct that the focus on the whole child was disappearing as educators focused solely on the cognitive aspects of their students. The purpose of this study was to examine the perceptions of recently graduated high school students in an effort to determine if …

Clinician’S Perceptions Of Neurofeedback Application And Effectiveness, Heidi Newman

Electronic Theses and Dissertations

ABSTRACT

Attention Deficit Hyperactivity Disorder (ADHD) affects children and adults alike. Finding an intervention that works for every individual is not an easy task. There is not a one size fits all strategy when considering interventions. Having multiple treatment options available to individuals is important for those diagnosed and affected by the disorder. Many parents are not aware of the attentive interventions available to their children, especially when that intervention is not medication. Dispersing valuable ADHD treatment information to educators and parents is a challenge that would benefit from further research and clinician engagement. In this study, clinicians that provide …

Medication Versus Brain-Based Treatment: Evaluation Treatment Preferences Of Parents Of Children With Adhd, Rebecca Recio-Swift

Electronic Theses and Dissertations

Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most prevalent neurodevelopmental disorders across the world. Currently, treatment for ADHD mostly consists of either medication or behavioral therapy or a combination of both. However, research has shown that medication used as therapy for the treatment of ADHD has side effects which parents deem undesirable for their children. Therefore, recent research has focused on patient and parent preferences. Studies have found that behavioral or other treatment options may often be chosen over medications. These same studies have documented the characteristics of parents that prefer certain treatments for their children. The purpose of this …

Using Modified Cover-Copy-Compare To Increase Math Fact Fluency And Promote Generalization, Juan Chen

Electronic Theses and Dissertations

Many elementary school students struggle with basic math fact fluency in the United States (Stickney et al., 2012). Cover-Copy-Compare (CCC) is a widely used intervention strategy that helps students who experience math fact fluency delays. This study aimed to modify CCC to improve four students’ math fact fluency. This study also aimed to modify CCC to generalize the target skill to more advanced skills. It was hypothesized that the intervention would increase participants’ target item fluency. It also hypothesized that the intervention would facilitate generalization to untrained target items and more difficult items. However, due to the impact of COVID-19, …

An Evaluation Of Programs And Leadership Practices For Effective Dropout Prevention, Nicole C. West

Electronic Theses and Dissertations

Abstract

This mixed-methods study explored a problem within dropout research which often fails to link characteristics of student subgroups with effective dropout interventions. Considering the characteristics identified in the literature of at-risk learners, the conceptual framework for this study combined the theory of self-efficacy and leadership with emphasis on servant leadership. The purpose of the study was to evaluate dropout intervention and prevention programs in two high schools by examining intervention and leadership practices for students at risk of dropping out of high school. Through causal-comparative and phenomenological approaches, this investigation focused on identifying dropout factors targeted in the intervention …

Analysis Of Disproportionality In Discipline And The Effects Of Positive Behavior Supports Within Special Education, Cutler T. Ruby

Electronic Theses and Dissertations

Nationwide, school districts are required (IDEA, 2004) to implement positive behavior interventions and supports (PBIS) for all students receiving special education services. These PBIS are reported to reduce problem behaviors and increase prosocial behaviors when implemented with fidelity (Crone et al., 2015). With a reduction of problem behaviors an expected reduction of discipline referrals should follow along with a reduction in days spent in exclusionary discipline for students in special education. Reducing days in exclusionary discipline is desired due to a strong research base linking the practice to several negative outcomes (Marchbanks et al., 2015) along with data demonstrating these …

A Study Of The Association Of Teacher Efficacy And Students' Achievement In A North Texas School District, Ruth E. Schackmann

Electronic Theses and Dissertations

The field of education places great importance on measurable student achievement and the role of teaching competencies for maximizing success. Whereas much focus has been given to professional development and improving teachers’ skills, this quantitative study examined whether teachers' self-efficacy and judgment about their skills and capabilities were significantly associated with improving student achievement in third grade reading. This dissertation involved a study of teacher self-efficacy using a sample group of third grade English/Language Arts teachers from one Texas urban school district. Targeted teachers were invited to complete a valid and reliable teacher efficacy survey, the Tschannen-Moran and Woolfolk Hoy …

Molecular Dynamics Simulations Provide Insight Into Stability Of Hyperthermophilic Endoglucanases, Logan E. Sheffield

Electronic Theses and Dissertations

Endoglucanases play a key role in the industrial production of bioethanol, but the most efficient method requires the utilization of high temperatures and is currently limited by the thermostability of endoglucanases. For this reason, it would be beneficial to discover more high-efficiency, thermostable enzymes to utilize in the hydrolytic process. In this study molecular dynamics simulations were performed on structurally similar endoglucanases with varying levels of thermostability to gain insight on what factors contribute to thermostability in endoglucanases. RMSD, RMSF, PCA, hydrogen bonding and salt bridges were analyzed. Finally, protein energy networks were constructed from nonbonded interaction potentials and analysis …

Critical Thinking In Law Enforcement Training Academies: A Phenomenological Study Of Officer Experiences, Billy J. Spruill

Electronic Theses and Dissertations

Recently, law enforcement officer use of force incidents resulting in death has seemingly become more prevalent. Generally, the educational requirement for a law enforcement officer is a high school diploma or general education development degree. One must question if this requirement is sufficient for a law enforcement officer to be successful in a modern world as the law enforcement training academy may be the law enforcement officer’s only postsecondary education. Critical thinking is a needed skill identified by high-stress professions such as the military, nursing, and disaster management, yet there is limited study regarding critical thinking in law enforcement. The …

Deposition And Diagenesis Of The Blossom Sand, Panola County, Texas, Hannah Chambers

Electronic Theses and Dissertations

The Late Cretaceous Blossom Sand within the Austin Group is a historic gas reservoir in the East Texas basin, located at depths of approximately 2,000 ft below the surface. Since the discovery of the Carthage Field in 1918 in the East Texas Basin, the Blossom Sand has produced approximately 26 BCF of gas with minor amounts of oil. Despite its notoriety in the Carthage Field, there is very little research that has been conducted on this unit, although it crops out in northeast Texas and is found in the subsurface of southwest Arkansas, western Louisiana, and the East Texas Basin. …

School Leaders And Exclusionary Practices: A Study Of Discretionary Daep Placements For Minority Special Education Students, Tiffany Laine Weiss

Electronic Theses and Dissertations

This study addressed the perceptions of assistant principals, counselors, and school district-level administrators about the overrepresentation of minority special education students in district alternative education placements. The purpose of this study was to examine the discipline practices at three middle school campuses in one 6A urban school district to understand minority special education students’ overrepresentation in discretionary district alternative education placements. The researcher conducted one-on-one interviews with assistant principals, counselors, one dean of students, one assistant superintendent, and one special education director. A document analysis and a data review were conducted to triangulate the results. The findings indicated that years …

Clash Of Titans: An Ethical Framework Towards Limitations In Religious Accommodation Within Healthcare, Yoelit Lipinsky

Electronic Theses and Dissertations

In late October 2017, a young Canadian Jewish man was at the center of a storm that involved ethics, religion, law and policy He had been unconscious for a month and doctors deemed him brain dead. The Jewish community, and his family, wished to keep him on life support, since their religion did not consider brain death to be ‘death.’ This clash between medical and religious perspectives poignantly illustrates the unique and growing challenges posed by religious observance in Canada’s secular healthcare system. A similar story is found in America. In December 2019, a story was published demonstrating fears that …

Unicorns Are Not Real And Neither Are You: Peter S. Beagle's Postmodern Fairy Tale, Athena Hayes

Electronic Theses and Dissertations

Although considered by many readers to be a “cult classic,” Peter S. Beagle’s 1968 novel The Last Unicorn has been unrepresented in literary scholarship. Many fantasy critics in the past have dismissed the work as lacking a sense of reality through its mixing of modern language with a medieval, fantasy setting. However, the novel’s purposeful muddling of reality raises questions of ontology and the nature of storytelling/world-projection. The objective of this study is to not only to act as a sort of apologetic for The Last Unicorn, but also read the novel in the context of fairy tale/mythic studies …

Radiosonde High Altitude Measurements Of Radiation Levels And Cosmic Ray Events, Ayodeji Opeyemi Akinuliola

Electronic Theses and Dissertations

Just above us, cosmic rays are hurtling in from space. These fast moving particles crash uncontrollably into molecules in the atmosphere, causing spontaneous decays of these particles. Despite the fact that we are broadly shielded from this radiation on earth, these particles can still disturb humans and electronics alike. Therefore, this research focuses on expanding the use of long-range radio transmitters such as radiosondes to transmit valuable data such as cosmic ray flux, geographical position, atmospheric temperature, pressure, etc. This can improve real-time radiation monitoring for aviation industry crew and passengers working in potentially higher radiation environments. On March 11, …