Digital Commons Network^™

Identifying Correlates Of Protection Of A Pneumonic Plague Vaccine., Caleb Samuel Whitley

Electronic Theses and Dissertations

Pneumonic plague is caused by inhalation of the bacterial pathogen Yersinia pestis. The immune response during Pneumonic plague occurs in two phases; an initial asymptomatic phase followed by a highly inflammatory and destructive phase resulting in 100% mortality if left untreated. The rapid onset of severe disease following the asymptomatic phase makes it difficult to administer antibiotics in time to prevent lethal outcomes. Therefore, the development of an effective vaccine is likely needed to combat pneumonic plague in areas of the world where Y. pestis remains endemic. One candidate subunit vaccine is protective in mice, a natural host for …

Direct And Satellite-Based Quantification Of Greenhouse Gas Fluxes In Small Ponds., Mark Christopher Tierney

Electronic Theses and Dissertations

As evidenced by their historic losses due to anthropogenic activities, wetlands are undervalued ecosystems that provide numerous ecosystem services, from recreational opportunities to carbon (C) storage. However, these wetlands are also the largest natural source of atmospheric methane (CH₄). Additionally, small water bodies (< 10,000 m²) are disproportionately large emitters relative to larger lakes and reservoirs. As construction and restoration efforts proceed, it is crucial to identify wetlands that need restoration and to understand the factors driving both greenhouse gas (GHG) fluxes and the C balance of these systems. This dissertation investigates the drivers of greenhouse gas fluxes …

A Comparision Of Teachers' Ratings Of Published Versus Ai-Generated Descriptions Of Evidence Based Practices In Education., Lora T. Hall

Electronic Theses and Dissertations

The persistent gap between educational research and classroom practice continues to limit teachers’ use of evidence-based practices (EBPs), despite strong empirical support and federal mandates encouraging their implementation. A key barrier to closing this research-to-practice gap is the limited accessibility, usability, and perceived relevance of traditional research dissemination formats. With the rapid rise of artificial intelligence (AI) tools capable of summarizing and restructuring complex information, this study examined whether AI-generated practitioner-oriented descriptions of an EBP would be rated differently from a published practitioner article on the same practice. Using an experimental cross-sectional survey design, 70 in-service teachers were randomly assigned …

Integrating Due Process Into Large Language Models., Joshua Paul Johnson

Electronic Theses and Dissertations

This research investigates the ability of large language models (LLMs) to recognize due process issues. Due process is a legal concept focused on the protection of the individual during interactions with government when life, liberty, or property are being impacted. Due process presents both substantive and procedural aspects that are challenging to incorporate into generative artificial intelligence. Through assessing model performance, creating benchmarking techniques, retrieval-augmented generation (RAG), and fine-tuning, this work seeks to measure due process recognition performance and improve performance in identifying due process issues. The results of evaluating larger parameter LLMs such as from Google, Meta, and OpenAI …

Understanding Social And Cognitive Influences In Medical Students' Learning Processes For Step 1: An Interpretivist Case Study., Ashley Elaine Triplett

Electronic Theses and Dissertations

This qualitative interpretivist case study explores, at a singular institution, medical students’ perspectives on the social and cognitive factors influencing the learning process as students prepare for the Step 1 examination. While prior research regarding medical students Step 1 preparation have focused primarily on wellness, stress, and career outcomes, limited studies have examined medical students' lived experiences to navigate what occurs during the learning process while they prepare for this critical exam. Utilizing a qualitative case study approach, this dissertation draws on fourteen student interviews, seven that passed Step 1 on their first attempt, and seven that failed. Findings reveal …

Building Bridges: An Appreciative Inquiry Approach To The Development Of Professional Learning To Enhance Teacher–Student Relationships For Students With Emotional Behavioral Disorders., Renee Renz

Electronic Theses and Dissertations

Positive teacher-student relationships are essential to student success yet are often difficult to create and maintain with students identified with Emotional Behavioral Disorders (EBD). Students with EBD frequently struggle with emotional regulation and disruptive behaviors, making relationships and trust both essential and challenging. This study addressed the need for professional learning that equipped educators with strategies to build and maintain positive relationships with students with EBD in secondary school settings. Guided by a participatory action research design, this study used Appreciative Inquiry as a framework for engaging expert secondary teachers from Kentucky in co-constructing professional learning. Appreciative Inquiry focused on …

The Autonomic And Arrhythmogenic Effects Of Gestational E-Cigarette Exposure., Brittany Rachelle Reynolds

Electronic Theses and Dissertations

Introduction. E-cigarettes (e-cigs) have been shown to be pro-arrhythmic in both human and male rodent studies; however, little is known about how e-cig use impacts patients with a predisposed heightened risk for arrhythmias, including pregnant women. Both pregnancy and e-cig use have independently been shown to increase heart rate, diminish heart rate variability, and increase ventricular premature beats, which is suspected to be due to sympathetic dominance. Importantly, β-blockers have been shown to reduce sympathetic activity, reduce heart rate, increase HRV, and reduce arrhythmias. Thus, the use of β-blockers may help prevent adverse health effects driven by sympathetic dominance from …

How Fundraisers Met Goals During The Covid-19 Pandemic, Cody C. Greene

Electronic Theses and Dissertations

The COVID-19 pandemic disrupted nearly every aspect of higher education operations, including fundraising and donor engagement. This qualitative study explored how Vice Presidents for Advancement and other senior fundraising leaders in higher education adapted their practices to meet fundraising goals during the pandemic. Using a narrative design, in-depth interviews were conducted with nine participants representing diverse institutions in the southeastern United States. Braun and Clarke’s (2006) six-phase thematic analysis was used to code and interpret the data.

Seven major themes emerged: communications, technology, donor relations, managing a fundraising team, overall giving impact, successful strategies, and the future. Participants described how …

Deep Learning With Kalman Filter, Rexford Julius Quaye

Electronic Theses and Dissertations

This thesis presents an extension of the Kalman filter to handle nonlinear and non-Gaussian systems. The standard Kalman filter is optimal under Gaussian assumptions but struggles with more complex noise models. This work introduces a novel loss function based on the Mahalanobis distance, which incorporates the covariance structure of measurement errors, enabling the filter to adapt to non-Gaussian scenarios. The neural network framework is applied to predict the system’s process model, while retaining the classical Kalman measurement update. The proposed methodology is demonstrated through examples of car position and rocket altitude tracking. The results show that the new approach performs …

Tennessee K-3 Teachers’ Perceptions Of Structured Literacy Curriculum Based On The Science Of Reading: A Phenomenological Approach, Amy L. Reece Townsend

Electronic Theses and Dissertations

The focus of this study was to explore the perceptions and knowledge of Tennessee kindergarten, first-grade, second-grade, and third-grade teachers regarding early literacy and science-based curricula that incorporate the science of reading. This study examined the experiences of kindergarten through third-grade teachers in a Tennessee school district as they transitioned to a structured literacy approach grounded in the science of reading. The goal was to understand how teachers adapted to the new methods, what helped them succeed, and what challenges they faced during the change.

Data collection included in-depth, semi-structured interviews. Analysis of data occurred in three phases: (a) categorization …

Uncovering Conserved Biosynthetic Gene Clusters And Interbacterial Interactions Of Myxobacteria In Polymicrobial Communities, Shailaja Khanal Pokharel

Electronic Theses and Dissertations

Myxobacteria are prolific producers of specialized metabolites and key contributors to microbial interactions within soil and other environments, yet fundamental questions remain about the conservation of their biosynthetic capacities and the dynamics that shape their coexistence with neighboring microorganisms. This dissertation addresses these gaps through three integrated research directions. In Chapter 2 we utilized a pan-genome framework across eleven genera and 195 sequenced genomes,including ten newly reported isolates, and found five BGCs were identified as the conserved BGCs across the Myxococcota. These clusters encode metabolites with established ecological functions, none of which are known toxins, suggesting selective maintenance of signaling …

Southern / Appalachian Migrants And Urban Development Politics In Uptown Chicago, 1950-1972, Charles Wayne Dowdy

Electronic Theses and Dissertations

This thesis investigates how ideas of interregional migration were used in service of urban renewal agendas in Uptown Chicago from 1950 to 1972. It argues that The South and Appalachia as regional ideas were impactful in postwar midwestern urban development politics, even as regional identity was less powerful as an adhering force for actual migrants in comparison with factors of race and class. Chapter 1 examines the development and use of the urban enclave model of interregional migration by the Uptown Chicago Commission in the late 1950s. It argues that anxieties around suburbanization and urban decline fueled the production of …

The Relationship Between Exercise And Prospective Memory: A Meta-Analysis, Shaykhah Salman Alqahtani

Electronic Theses and Dissertations

Prospective memory (PM)—the ability to remember and carry out future intentions—is essential for everyday functioning. This cognitive process involves intention formation, retention, cue detection, and execution. Emerging research suggests that physical exercise may influence prospective memory performance through potential enhancements in attention, executive functioning, and neuroplasticity. This thesis examines the relationship between physical exercise and prospective memory through a systematic review and meta-analysis of the existing literature.

This review synthesized evidence from experimental studies to evaluate the effects of acute and chronic exercise interventions on prospective memory in diverse populations. Six studies met the eligibility criteria and were included in …

Racial And Ethnic Differences In The Associations Between Alcohol Use Disorder, Aggression, And Suicidality Among Adolescents With Ptsd, Gabrielle Armstrong

Electronic Theses and Dissertations

The comorbidity of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) is well documented and associated with elevated risk of aggression and suicidality among certain populations. However, no research to date has examined these associations among adolescents. Using data from the National Comorbidity Survey-Adolescent Supplement (NCS-A), the present study examined whether the presence of AUD was associated with greater outward aggression, suicidal ideation, and attempts, and whether these associations differed across race/ethnicity, in a weighted sample of 737,996 adolescents with PTSD (10.3% Hispanic, 16.4% Black, 73.3% White). AUD presence was significantly associated with higher odds of breaking items, attacking …

The Impact Of State-Mandated High-Stakes Standardized Testing On The Job Satisfaction Of Third-Grade Reading Teachers In Mississippi, Jenny Kate Ernst

Electronic Theses and Dissertations

This qualitative study examined how state-mandated standardized testing influences the job satisfaction of current and former third-grade reading teachers in Mississippi. Guided by Self-Determination Theory, Herzberg’s Two-Factor Theory, and the Job Demands-Resources Model, the research explored how accountability pressures shape teachers’ motivation, emotional well-being, and instructional autonomy. Data were collected through an open-ended online survey of current and former Mississippi third-grade reading teachers. Analysis of responses revealed four central themes: emotional strain and burnout, loss of autonomy and creativity, impact on instructional practices, and student impact. Findings indicated that teachers perceive standardized testing as a major source of stress that …

Design And Prototyping Of An Acoustic Positioning System For Gps-Denied Environment, Harley Hogan Garrett

Electronic Theses and Dissertations

Finding the placement of sensors is known as sensor localization, and is a necessary task to ensure that a network is capable of array processing operations, such as direction of arrival measurements. This thesis proposes a method to perform sensor localization for a wireless sensor network using acoustics. Each sensor is equipped with a microphone, speaker, and processor. Using these, the proposed system is able to find the distance between each sensor and later the geometry of the network. A series of optimizations help reduce error and improve the final accuracy of the system to within 6.5 cm. The proposed …

Reading Teacher Perceptions: The Impact Of Educator Preparation Program Literacy Coursework And Clinical Experiences On Teacher Efficacy In Historically Underrepresented Populations, Emily Taubken

Electronic Theses and Dissertations

Despite research that indicates the critical importance and lifelong impact of early reading proficiency for students, national reading proficiency trends demonstrate most students in the United States are not yet reading at grade level, with disparities existing among historically underrepresented subgroups. Additionally, research shows that preservice and in-service teachers have documented limited feelings of self-efficacy in teaching reading specifically, suggesting limitations in preservice training for educators. To better understand how reading teachers perceive the efficacy of their preservice teacher academic and clinical experiences, especially for those who serve historically underrepresented student populations, this study seeks to document the perspectives of …

Stochastic Functional Data-Driven Models For Real-Time Battery Health Forecasting Under Dynamic Operating Conditions, Joshua Owusu

Electronic Theses and Dissertations

This thesis provides an effective statistical model to predict the real-time state of lithium-ion batteries for reliable Battery Management Systems (BMS). It highlights battery data (voltage, current, temperature) as smooth functional curves. The principal method demonstrates diminishing trends to health outcomes like State of Health (SoH) and Remaining Useful Life (RUL) by employing Functional Principal Component Analysis (FPCA) and Bayesian Functional Linear Models (FLMs). The primary objective is to figure out how uncertain forecasts are. Simulations demonstrate that the highest accuracy (lowest MSE) is achieved through low noise levels along with large sample sizes. The final system provides a highly …

The Development Of Teacher-Student Relationships In The Elementary School Setting And Their Influence On The Whole Child, Jana H. Kline

Electronic Theses and Dissertations

The relationship students have with teachers can influence their social development, behavior, and academic performance. Some teachers naturally build positive relationships with students while others may not realize the importance or know how to build them unless specific strategies are given. The purpose of this phenomenological, qualitative research study was to examine teacher perceptions of the development of relationships with students in the elementary school setting and their influence on the whole child.

To address this purpose, data collection strategies included individual interviews with elementary school teachers. Analysis of data involved transcribing interviews and line-by-line coding. Themes regarding teacher-student relationships …

Visualizing The Fretboard: Arpeggiated Patterns, Muscle Memory, And Neurocognitive Strategies For The 5-String Electric Bass, Matthew Alexander Woisin

Electronic Theses and Dissertations

Proficient navigation of the 5-string electric bass requires a comprehensive mastery of various techniques and a solid understanding of music theory. This includes a detailed grasp of arpeggios, chord extensions, and the development of deeply ingrained muscle memory for precise execution. This thesis introduces a structured methodology that refines existing fretboard visualization techniques and applies a unique manner of fretboard mapping, offering a more precise framework for comprehending and unlocking the full range of the instrument. By drawing insights from music theory, music education, cognitive science, neuroscience, and technology this approach is achieved by synthesizing research on visual pattern recognition, …

Topic Modeling And Culturomic Analysis Of 30,000 Books Over 100 Years Using Gensim, Michael A. Freeman

Electronic Theses and Dissertations

This thesis explores the cultural influence of historical events on English-language fiction published between 1820 and 1929. Using a corpus of 30,256 digitized books from Project Gutenberg, Latent Dirichlet Allocation (LDA) topic modeling was applied to identify recurring themes across eleven decades. The study sought to determine whether historically significant events could be detected within fictional narratives. One clear instance emerged: Napoleon Bonaparte and the Napoleonic Wars appeared explicitly in the 1820s corpus. Beyond this, several thematic patterns were observed—such as maritime language in the 1840s, national identity in the 1880s, and youth-oriented dialogue in the early 20th century—that plausibly …

Examing Fear Conditioning/Extinction And The Role Of The Amygdala In Human Neuroimaging., Olivia Cook

Electronic Theses and Dissertations

Fear plays a crucial role in survival but can lead to psychological disorders when dysregulated. Fears can be innate due to evolutionary relevance or learned through associative processes, where predictive accuracy of threat is pivotal. Disruptions in fear neurocircuitry contribute to anxiety disorders, characterized by heightened activation and impaired learning. Fear conditioning and extinction paradigms based on classical Pavlovian conditioning have been used to study mechanisms underlying fear learning. Using this experimental model, fear networks in rodents have been described in detail with clear distinction between conditioning and extinction neural functioning. Yet, there is no consensus on the neurobiological processes …

Spectroscopic Studies Of Metal Containing Molecules Under Jet-Cooled Conditions Using Laster-Induced Fluoresence (Lif) And Dispersed Fluorescence (Df) Techniques., Md Touhidul Islam

Electronic Theses and Dissertations

This dissertation examines the jet-cooled spectroscopy of the calcium propoxide radical (CaOC₃H₇) to understand how increasing molecular complexity reshapes symmetry, electronic degeneracy, and vibronic coupling. Moving from Ca–OCH₃ to Ca–OC₃H₇ lowers symmetry (C₃v → Cs → C₁) and exposes effects such as spin–orbit splitting and both Jahn–Teller and pseudo–Jahn–Teller distortions. These features remodel the excited-state potential surfaces and are directly observable with laser-induced fluorescence (LIF) and dispersed fluorescence (DF). A central goal is to evaluate whether CaOC₃H₇ supports the near-diagonal vibronic branching needed for efficient optical cycling, while also highlighting implications for catalysis and astrochemistry, where precise spectral fingerprints guide …

The Role Of Law Enforcement In Sexual Assault Kit Submissions: A Statewide Analysis Of Decision-Making Processes & Focal Concerns In Kentucky., Rychelle Elizabeth Wilks

Electronic Theses and Dissertations

Sexual assault case attrition persists throughout the criminal justice system, partly due to inconsistent Sexual Assault Kit (SAK) submission decisions. This dissertation examines factors influencing police officers' decisions to submit SAKs for forensic testing, applying the focal concerns perspective to understand how legal and extra-legal characteristics shape these decisions. Using statewide Kentucky data from July 2007 to March 2018, this study analyzed 2,194 adult sexual assault cases from 192 law enforcement agencies. Of these cases, 1,520 (69.3%) resulted in SAK submission. Logistic regression analyses examined the full sample, as well as four subsamples. Results provide mixed support for focal concerns …

Symmetry, Stability, And Robust Optimization Strategies For Nonorthogonal Multiconfiguration Self-Consistent Field Wavefunctions., Zihui Song

Electronic Theses and Dissertations

The "different orbital different configuration" (DODC) framework is a general formulation of multireference wavefunctions that allows each configuration (determinant) to possess its own set of optimized molecular orbitals, rather than sharing a common orbital basis as in conventional orthogonal configuration interaction (CI) or Complete Active Space Self-Consistent Field (CASSCF) methods. One prominent example of the DODC framework is the Nonorthogonal Configuration Interaction (NOCI) method, which relaxes the orthogonality constraint between the orbitals of different configurations. This relaxation enables a compact yet flexible description of systems exhibiting strong correlation. By employing multiple nonorthogonal reference determinants, NOCI naturally incorporates orbital relaxation and …

Characterizing The Ethanol Sensitivity Of The Planar Cell Polarity Pathway In Endoderm Morphogenesis And Jaw Development., Raéden Omneil C. C. Rolle Gray

Electronic Theses and Dissertations

Fetal Alcohol Spectrum Disorders (FASD) describes a large range of developmental defects due to prenatal alcohol exposure. It is characterized by neural and facial defects, including jaw hypoplasia. Many factors contribute to the susceptibility of ethanol-induced facial defects, including genetics, yet the genes involved, and the cell events they regulate, are poorly understood. Zebrafish have a large number of tools for genetic manipulation available, share 70% of genes with humans, are fertilized externally and are translucent during embryogenesis, making them great models to study FASD. Previous studies show that two members of the Planar Cell Polarity (PCP) pathway, zebrafish vangl2 …

Artificial Intelligence For Cancer Imaging: Integrated Frameworks For Hepatocellular Carcinoma And Pulmonary Nodules., Ahmed Muhammed Sherif Mostafa Alksas

Electronic Theses and Dissertations

Reliable, reproducible, and clinically useful artificial intelligence (AI) for oncologic imaging requires more than high headline metrics: it demands principled pipelines, calibrated predictions, and designs that generalize across anatomy, scanners, and institutions. This dissertation develops such pipelines in two complementary domains— hepatocellular carcinoma (HCC) on multiphase CT/MRI and indeterminate pulmonary nodules on thin-slice CT—while articulating evaluation and reporting practices that support credible clinical translation. The work proceeds in six core chapters. Two focused reviews synthesize the state of the art in (i) radiomics/AI for HCC and (ii) early assessment of lung nodules, mapping common pitfalls (data leakage, class imbalance, kernel …

Scalable Carbon-Based Electrodes For Hole-Transport Layer-Free Perovskite Solar Cells., Sharmin Akter

Electronic Theses and Dissertations

Perovskite solar cells (PSCs) have rapidly reached certified single-junction efficiencies near 26%, but deployment is still limited by operational instability, scale-up challenges, and the cost and complexity of typical device stacks. This dissertation explores a simpler, scalable approach: HTL-free PSCs using low-cost, chemically robust carbon (e.g., carbon black) counter electrodes compatible with low-temperature, solution processing. This work demonstrates how carbon-ink formulation, scalable deposition (blade vs. slot-die), and work-function-tuning additives control film quality, interfacial energetics, and device performance. Carbon inks were developed for both coating methods by systematically varying carbon-to-binder ratio, polymer chemistry, and solvent system. Among the binders screened, ethyl …

The Relationship Between Forgiveness And Religiosity In Counseling In The Saudi Population, Salman Alqahtani

Electronic Theses and Dissertations

Forgiveness is an important psychological process associated with religiosity, with both having been shown to support mental health and promote personal growth. Forgiveness remains understudied in Arab and Islamic societies, specifically in Saudi Arabia, where religiosity is an important cultural value. The purpose of this study was to gain a better understanding of the relationship between forgiveness and religiosity among Saudi college students in a faith-oriented and collectivistic society. Data were collected from 106 Saudi college students using the Arabic variation of the Forgiveness and Reconciliation Inventory (A-FRI) and the Arabic Inventory of Religiosity (AIR). Results showed a statistically significant …

Investigating The Origins Of Symbiosis Using A Novel Mycorrhizal Interaction In Pasque Flowers (Pulsatilla Patens), Savannah Lane Draud

Electronic Theses and Dissertations

Mycorrhizal fungi form mutualistic symbioses with most land plants, occurring primarily as arbuscular mycorrhizal (AM) fungi or ectomycorrhizal (ECM) fungi. Pulsatilla patens, an herbaceous perennial widely distributed across Eurasia and North America, belongs to a plant family historically known only to form AM associations. However, recent discoveries of ECM P. patens individuals in northeastern Poland raise questions about the mycorrhizal status and evolutionary trajectory of this species. Because ECM formation in this lineage is likely evolutionarily recent, P. patens offers a valuable system for investigating the ecological and historical factors that facilitate the emergence of ECM symbiosis.

Chapter 1 assessed …