Digital Commons Network^™

Investigating Host Defenses Of North American Salamanders Against The Recently Emerged Chytrid Pathogen, Batrachochytrium Salamandrivorans, Kenzie Pereira

Electronic Theses and Dissertations

A recently emerged chytrid fungal pathogen, Batrachochytrium salamandrivorans (Bsal) threatens salamander biodiversity. Bsal susceptibility varies between and within salamander species, but little is known about the mechanisms underlying these differences. Susceptibility is likely influenced by numerous interacting factors, but my dissertation studied the role of host immune responses.

My first aim investigated between species differences by studying the bioactive properties of salamander skin peptides against Bsal and the related pathogen, B. dendrobatidis (Bd). Skin peptides were collected from five salamander species, used for in vitro assays, and analyzed by RP-HPLC. While skin peptides from one …

Assessing The Risk Of Land Subsidence In The Lower Limpopo River Basin, Mozambique With Remote Sensing, Gabriella Zuccolotto

Electronic Theses and Dissertations

Land subsidence is a threat to coastal cities around the world. In the lower Limpopo River Basin, the presence of compaction-prone alluvial sediments, groundwater use, and reports of saltwater intrusion suggest that subsidence could be occurring. Using interferometric synthetic aperture radar (InSAR) from Sentinel-1, combined with in-situ sea level and river height measurements, this study aims to determine if land subsidence could contribute to increased saltwater intrusion. InSAR results indicate that subsidence in the lower Limpopo River valley has occurred at an average rate of -2.98 cm/yr based on data from the dry seasons (May to October) of 2017-2021. River …

Social Entrepreneurial Skills And Practices Of Occupational Therapists Engaging In Emerging Community Practice Roles: A Working Theory Of Practice Improvement, Retta M. Martin

Electronic Theses and Dissertations

The purpose of this mixed-methods study was to explore the relationship between emerging practice in occupational therapy and social entrepreneurship by examining the behaviors and skills used by occupational therapists who are engaged in emerging practice. Five occupational therapists who engage in emerging practice were recruited to participate. The occupational therapists completed two surveys related to behaviors and competencies of social entrepreneurs. The participants also completed a semi-structured interview regarding behaviors, competencies and the occupational perspective of their practice.

Quantitative data was analyzed through descriptive statistics. The quantitative data determined a relationship between the skills used by social entrepreneurs as …

Mathematical Models Yield Insights Into Cnns: Applications In Natural Image Restoration And Population Genetics, Ryan Cecil

Electronic Theses and Dissertations

Due to a rise in computational power, machine learning (ML) methods have become the state-of-the-art in a variety of fields. Known to be black-box approaches, however, these methods are oftentimes not well understood. In this work, we utilize our understanding of model-based approaches to derive insights into Convolutional Neural Networks (CNNs). In the field of Natural Image Restoration, we focus on the image denoising problem. Recent work have demonstrated the potential of mathematically motivated CNN architectures that learn both `geometric' and nonlinear higher order features and corresponding regularizers. We extend this work by showing that not only can geometric features …

Weathering The Storm: Navigating Urban Ecologies Of Communication In Times Of Crisis, Austin Hestdalen

Electronic Theses and Dissertations

This project explores cities as urban ecologies of communication in which crises emerge and are given significance within the dialogic relations cultivated among public actors attempting to make a living, together, within the shared historical-cultural contexts of everyday life. To describe cities as urban ecologies of communication is to describe them in terms of urban communication and its interdisciplinary foundations in the study of rhetoric, philosophy, planning, policy, architecture, sociology, geography, and media. The first chapter introduces the challenges of urban risk and crisis management within the complex ecologies of communication constituted by cities and reviews how ‘risk’ and ‘crisis’ …

Without Permanence: Mapping Multi-Genre, Cross-Disciplinary Frameworks For Trans* Studies, Jesse Jack

Electronic Theses and Dissertations

This project takes a cross-disciplinary and multi-genre approach to Transgender (Trans*) Studies to proliferate diverse and ambiguously-gendered representations of trans* experiences across time. It identifies the emergence of rhetorical intertextuality in recent trans* literatures as a discursive response to the biopolitical regulation and erasure of ambiguously-gendered, trans* experiences. It identifies the intersecting influences of twentieth- and twenty-first-century medical paradigms, surveillance apparatuses, popular trans* autobiographies, and archives in representing and exceptionalizing certain trans* experiences over others. In contrast, this project engages in a close reading of Pajtim Statovci’s Crossing (2016) and Andrea Lawlor’s Paul Takes the Form of a Mortal Girl …

Ethical Oversight Of Roles & Relationships In Treatment & Research In Advanced Disease States, Alexa Vercelli

Electronic Theses and Dissertations

There is often ethical analysis focusing solely on the care of the patient by the physician or on the protection of the research participant by the clinical investigator, but those two are often overlapping. By paralleling the analysis of treatment and research, it emphasizes the specific ethical approaches necessary for individuals facing advanced diseases states in the separate roles of being a patient or participant. It also gives guidance to the complexity of the ethics surrounding medical professionals who float between the roles of treating physicians and clinical investigators. As individuals with advanced disease states are considered a vulnerable population …

The Effects Of Digital Game-Based Instruction On Knowledge Acquisition And Retention Of Genetics Content, Brinley Kantorski

Electronic Theses and Dissertations

Digital educational games have been a part of the educational landscape since the early 1970s. Since then, there has been a proliferation in the quantity, format, type, and quality of digital educational games available to classroom teachers. Despite this, the body of literature surrounding the effectiveness of these digital educational games remains highly fragmented and lacks unifying themes. While some literature exists to support the use of digital educational games in immediate knowledge acquisition, little research has been done on how digital educational games impact the retention of knowledge in the long term. As such, this study examines how the …

The Effectiveness Of An Evidence-Based Performance Feedback Intervention Through Zoom Communications, Inc., Kristen Mahony

Electronic Theses and Dissertations

The current study was conducted during the COVID-19 pandemic after the American Psychological Association (APA) called for modified research practices to ensure the safety of students and families. The evidence-based writing fluency intervention known as the Performance Feedback (PF) Intervention was implemented via a fully remote platform. A single-subject multiple-baseline across participants design was utilized to evaluate the effects of the adapted intervention on the writing skills of three elementary-aged students with disabilities while also measuring maintenance of those skills two weeks following the intervention. Additionally, researchers measured the social acceptability of the virtual PF intervention by the students. Visual …

Geochemical Characterization Of The Bone Spring Formation, Delaware Basin, Using Chemostratigraphy And Integrated Petrophysics, David Tonner

Electronic Theses and Dissertations

The Delaware Basin forms part of West Texas's and New Mexico’s famous petroleum-generating Permian Basin. The Bone Spring Formation is a prolific hydrocarbon producer within this basin, creating one of the world’s richest oil shales. This formation has lithological sequences that are characterized by repeating carbonate and siliciclastic intervals of a third-order cycle which can largely be correlated to highstand and lowstand systems tracts, respectively. Lithological complexity and facies change are manifested by debris flows, turbidites, and slumps. In addition to glacio-eustasy, both tectonism and broader Milankovitch cycles have influenced the depositional history. Previous investigations have utilized cores and wireline …

Effect Of Dorsal Quadrant Or Ventral Quadrant Spinal Cord Injury On Gait Features During Locomotion., Anya Nicole Trell

Electronic Theses and Dissertations

In the Unites States, approximately 1.5 million people currently have a spinal cord injury and suffer permanent sensory and motor loss due to the disruption of the spinal cord. Due to the significant morbidity, it is vital to understand the functional impact of disrupting neural descending pathways that modulate spinal neurons involved in intermuscular coordination critical for gait behaviors. Tasks that are more difficult require additional input from these neural pathways; therefore, fourteen feline subjects were familiarized with level overground locomotion and stair descent gait tasks. After collection of baseline kinematic data, the subjects received either a dorsal or ventral …

Classifying The 2022 Status Of Tsuga Canadensis (Eastern Hemlock) Along The Kentucky Portion Of The Pine Mountain Wildlands Corridor., Grace M. Embree

Electronic Theses and Dissertations

The invasion of the Hemlock Woolly Adelgid (HWA) (Adelges tsugae) has posed a continual threat in the United States to the Eastern Hemlock (Tsuga canadensis) trees since the 1950s. HWA feed on eastern hemlock needles, reducing the amount of healthy photosynthesizing vegetative area. The use of satellite imagery has been instrumental in identifying areas of eastern hemlock presence. Satellite platforms like Landsat and AVIRIS are commonly used for identification, classification, and mapping of eastern hemlock. Sentinel-2 imagery was released in 2015 for free access. It has a finer spatial grain of with the majority of the …

Search For A Dark Leptophilic Scalar Produced In Association With Taupair In Electron-Positron Annihilation At Center-Of-Mass Energies Near 10.58 Gev., Diptaparna Biswas

Electronic Theses and Dissertations

Dark matter is believed to be a form of matter which seemingly accounts for approximately 85% of the matter in the universe and about 27% of its total mass–energy density. It doesn't participate in electromagnetic interaction, i.e. doesn't interact with light. Consequently, we cannot see it using optical or radio telescope and hence the name dark matter. However, it participates in gravitational interaction, and we hypothesize its existence based on a variety of astrophysical observations, including gravitational effects, that cannot be explained by the accepted theories of gravity unless we account for more matter than can be perceived through electromagnetic …

Development And Applications Of A Sensor For Measurement Of Different Modes Of Heat Transfer On Foods In A Residential Oven., Kervins Petit-Bois

Electronic Theses and Dissertations

Thermal characterization of an oven is an important part of designing an oven. Understanding how changes in cooking algorithm, oven construction, and oven materials affect cooking performance is critical in ensuring that an oven is properly designed. Often temperature data is used to characterize oven behavior, but this neglects the mode of heat transfer used to achieve these temperatures. Several studies have compared the different modes of heat transfer and cooking performance and have shown that cooking performance in radiation dominated modes are different than in convection dominated modes. The goal of this study is to develop a heat flux …

Disparate Sense Of Exclusion Between Young People Of Color Living Within Variable Social Infrastructures., James M. Joyce

Electronic Theses and Dissertations

I analyzed transcripts of listening sessions with youth/young adults of color in 2021-2022 for the purpose of addressing local racial inequity during COVID-19. I used inductive coding methods and found three themes on sense of exclusion to be most salient. These themes related to racial exclusion, exclusion of social infrastructures in the community, exclusion of young people of color by people working in schools and other public settings, and exclusion or disconnection of young people of color from opportunities for building community. I show how these themes vary across some dimensions of the local social infrastructure, and I discuss implications …

Defining The Importance Of The Hnrnp I Interaction To The Sindbis Virus Subgenomic Viral Rna Using An Innovative Tethering Approach., Claire Westcott

Electronic Theses and Dissertations

Old World alphaviruses cause significant outbreaks of illness and debilitating multi-joint arthritis for prolonged periods. Currently, there are no FDA approved vaccines or antiviral therapies; and thus, there is a critical need to identify and characterize the molecular biology of alphaviruses. Alphaviruses rely on the host cell machinery to complete the viral lifecycle and are dependent on interactions with host RNA binding proteins. Accordingly, several host heterogenous nuclear ribonucleoprotein proteins (hnRNPs) have been found to bind to the Sindbis virus (SINV) RNAs. Disrupting the interaction sites in the viral RNAs of these RNA:Protein interactions results in decreased viral titers in …

The Effect Of Typewriting Vs. Handwriting Lecture Notes On Learning: A Systematic Review And Meta-Analysis., Timothy Schaun Lau

Electronic Theses and Dissertations

This study is a systematic review and meta-analysis of studies examining the effect of note-taking modality during lecture, that is, taking notes by hand using pen and paper vs. taking notes using a keyboard and computer, on learning among secondary and postsecondary students. I begin with a review of the literature and theoretical introduction to the theories and terms used. From a theoretical standpoint, there are strong reasons to believe that taking notes by hand might offer recall benefits relative to taking notes using a computer and keyboard. At the same time, I point out that one problem, which I …

Computer Aided Diagnosis System For Breast Cancer Using Deep Learning., Asma Baccouche

Electronic Theses and Dissertations

The recent rise of big data technology surrounding the electronic systems and developed toolkits gave birth to new promises for Artificial Intelligence (AI). With the continuous use of data-centric systems and machines in our lives, such as social media, surveys, emails, reports, etc., there is no doubt that data has gained the center of attention by scientists and motivated them to provide more decision-making and operational support systems across multiple domains. With the recent breakthroughs in artificial intelligence, the use of machine learning and deep learning models have achieved remarkable advances in computer vision, ecommerce, cybersecurity, and healthcare. Particularly, numerous …

Properties And Classifications Of Certain Lcd Codes., Dalton Seth Gannon

Electronic Theses and Dissertations

A linear code $C$ is called a linear complementary dual code (LCD code) if $C \cap C^\perp = {0}$ holds. LCD codes have many applications in cryptography, communication systems, data storage, and quantum coding theory. In this dissertation we show that a necessary and sufficient condition for a cyclic code $C$ over $\Z_4$ of odd length to be an LCD code is that $C=\big( f(x) \big)$ where $f$ is a self-reciprocal polynomial in $\Z_{4}[X]$ which is also in our paper \cite{GK1}. We then extend this result and provide a necessary and sufficient condition for a cyclic code $C$ of length …

Rewriting Writing As Transmodal And Translingual: Tranßcribing Japanese., Alex Way

Electronic Theses and Dissertations

This dissertation analyzes the use of different scripts in Japanese writing practices to disrupt English-language and Western-centric approaches to multimodal composition. Early chapters establish a brief history of the Japanese writing system (JWS) and explore its functionality. I trace the JWS’s development from borrowed Chinese characters (kanji), which were adapted to the Japanese language through the translation process of kundoku, to the contemporary system which utilizes the supplemental phonetic scripts of hiragana and katakana, in part, to represent Japanese syntax. Building on this historical context, I demonstrate how the use of the Japanese multi-scripts (hiragana, katakana, and kanji) in conventional …

Investigating The Shared And Unique Mechanisms Of The Development Of Comorbid Eating Disorder-Anxiety Symptoms During Adolescence., Leigh Cara Brosof

Electronic Theses and Dissertations

Introduction: Eating disorders are associated with significant morbidity, psychiatric comorbidity, and impairment. Despite the detrimental outcomes associated with eating disorders, effective treatments for eating disorders are lacking. One factor that has impeded the identification of targets for intervention in eating disorders is the high comorbidity rate with other psychiatric disorders. Comorbidity models can inform treatments by showing which mechanisms are shared in comorbidity and which mechanisms are unique to specific disorders. Anxiety disorders are the most frequently co-occurring disorders with eating disorders, as 85% of individuals with eating disorders have a comorbid anxiety disorder. One mechanistic process in both anxiety …

Pediatric Oncology Social Work Job Analysis., Alyssa Ashlyn Middleton

Electronic Theses and Dissertations

This dissertation is an examination of the tasks most important to the pediatric oncology social work role. It begins with an argument that pediatric oncology social work is a blend of four social work specialties: generalist medical social work, oncology social work, pediatric social work, and hospice and palliative care social work. Studies report pediatric oncology social workers feel unprepared for numerous tasks related to their role. Despite calls for increased education and training opportunities, few are available. Until now, there has been no study evaluating the tasks that pediatric oncology social workers deem most important to their role, nor …

Role Of Deep Learning Techniques In Non-Invasive Diagnosis Of Human Diseases., Hisham Abouelseoud Elsayem Abdeltawab

Electronic Theses and Dissertations

Machine learning, a sub-discipline in the domain of artificial intelligence, concentrates on algorithms able to learn and/or adapt their structure (e.g., parameters) based on a set of observed data. The adaptation is performed by optimizing over a cost function. Machine learning obtained a great attention in the biomedical community because it offers a promise for improving sensitivity and/or specificity of detection and diagnosis of diseases. It also can increase objectivity of the decision making, decrease the time and effort on health care professionals during the process of disease detection and diagnosis. The potential impact of machine learning is greater than …

Media Portrayal Of Private Prisons And Inmates., Ladye Anna L. Adams

Electronic Theses and Dissertations

Private prisons have existed in the United States since 1986, but research about prison privatization has been limited. To date, there have been two published studies examining how mainstream media sources frame prison privatization to their audiences. This thesis attempts to address this gap in the literature. Using content analysis, I evaluate how mainstream media frames prison privatization and inmates housed in private prisons. The analysis is conducted in two parts. The first tests if private prison reduction or expansion is the focus of the news story if framed using economic benefits, ethical concerns, or prisoner violence. The second tests …

Statistical Methods For Personalized Treatment Selection And Survival Data Analysis Based On Observational Data With High-Dimensional Covariates., Don Ramesh Dinendra Sudaraka Tholkage

Electronic Theses and Dissertations

Due to the wide availability of functional data from multiple disciplines, the studies of functional data analysis have become popular in the recent literature. However, the related development in censored survival data has been relatively sparse. In Chapter 2, we consider the problem of analyzing time-to-event data in the presence of functional predictors. We develop a conditional generalized Kaplan Meier (KM) estimator that incorporates functional predictors using kernel weights and rigorously establishes its asymptotic properties. In addition, we propose to select the optimal bandwidth based on a time-dependent Brier score. We then carry out extensive numerical studies to examine the …

Environmental Noise Exposure And Its Association With Elementary Standardized Testing Scores And Adult Mental Ill-Health In Louisville, Kentucky., Lindsey Adelle Wood

Electronic Theses and Dissertations

Background and Aim: The current body of literature on the associations of environmental noise exposure with varying psychological outcomes is inconclusive, with many conflicting findings. Limitations include exposure measurement error and lack of investigation of effect modification by important factors. This dissertation aims to expand on the current understanding of these relationships by limiting exposure measurement error and by assessing effect modification. Methods: We estimated the distribution of total environmental noise in Louisville, Kentucky for several time-periods using land use regression (LUR) methodologies. Additionally, through multiple regression models, we estimated the association of environmental noise during relevant time-periods with childhood …

An Analysis Of Public Comments On The Implementation Of The Ngss In Kentucky., Matthew David Trzaskus

Electronic Theses and Dissertations

Feedback has been a highly effective means to enact change. In the classroom teachers provide feedback to students concerning their performance, how they compare to the learning goal, and what students need to achieve those goals. For teachers, they utilize feedback from students to examine content focus and instructional practice in order to reflect and make positive changes. In this study, feedback is once again provided in order to enact change. Kentucky stakeholders, mainly teachers, in science education offered feedback about the implementation of the Next Generation Science Standards (NGSS). In their feedback they highlighted the challenges that occurred after …

Cross-Validation For Autoregressive Models., Christina Han

Electronic Theses and Dissertations

There are no set rules for choosing the lag order for autoregressive (AR) time series models. Currently, the most common methods employ AIC or BIC. However, AIC has been proven to be inconsistent and BIC is inefficient. Racine proposed an estimator based on Shao's work which he hypothesized would also be consistent, but left the proof as an open problem. We will show his claim does not follow immediately from Shao. However, Shao offered another consistent method for cross validation of linear models called APCV, and we will show that AR models satisfy Shao's conditions. Thus, APCV is a consistent …

Characterization Of Microbotryum Lychnidis-Dioicae Secreted Effector Proteins That Manipulate Its Host Plant, Silene Latifolia., Ming-Chang Tsai

Electronic Theses and Dissertations

The smut fungal species Microbotryum lychnidis-dioicae is an obligate phytopathogen colonizing the plant host, Silene latifolia. A significant feature of M. lychnidis-dioicae infection is that the fungus can replace pollen on the anthers of susceptible host plants with fungal teliospores, thus earning the fungus the name: anther smut disease of flowers. The fungus synthesizes and secretes effector proteins into the cells of the plant host during infection, and the protein-protein interactions may interfere with and modify metabolism, plant development, and gene expression of the host to allow fungal colonization. Two potential fungal effector proteins, MVLG_06175 and MVLG_05122, were identified …

Stability Analysis Of Ionically And Electronically Conductors In Energy Applications., Tanner D. Whatley

Electronic Theses and Dissertations

The increasing need of electrical power around the world creates the search for sustainable energy to become a major stride in the manufacturing industry. The pursuit of energy storage systems being better, longer lasting, lighter, and cost effective have been a priority for companies, but one of the most crucial attributes in a battery should be its safety without the reduction in performance. For energy conversion and storage devices, such as solar cells and batteries, many important components are sensitive to air or moisture, therefore, the stability studies are important. This thesis focuses on two representative materials: hydrogenated carbon nanosheets …