Digital Commons Network^™

Evaluation Of Supplementing Brewer's Yeast To Lactating Dairy Cows, Taylor Christine Aubrey

Electronic Theses and Dissertations

Probiotics have been used as effective, natural feed additives in the dairy industry to improve animal health and performance. Yeast product supplementation can be beneficial in the diet of lactating dairy cows by increasing feed efficiency, alleviating disease, and improving production performance under heat stress. Objectives of this study were to evaluate supplementing a concentrated brewer’s yeast in the ration of a lactating dairy cow by assessing milk yield and composition, blood metabolites, rumen fermentation, and feed intake and efficiency. We hypothesized that diets containing a concentrated brewer’s yeast supplement would increase milk and component yields, benefit rumen fermentation, and …

The Influence Of Chromium Supplementation On The Insulin Pathway, Carcass Traits, And Meat Quality Of Feedlot Steers, Heather Rode

Electronic Theses and Dissertations

Chromium supplementation (Cr) can increase efficiency of growth in livestock by amplifying insulin signaling. Previous research showed Cr increases nutrient utilization and changes in muscle growth and fat deposition. Therefore, the objective of this research was to determine how Cr affects carcass traits, meat quality, and the insulin pathway in feedlot steers. Calf-fed steers were allotted to 0 ppb (CON) or 400 ppb Cr propionate (Cr400) for 210d in experiment 1. Two longissimus muscle (LM) biopsies were collected to examine protein abundance and gene expression after adaptation to a terminal implant and after adaption to ractopamine hydrochloride (RAC). A follow …

Development And Application Of A Fish-Based Index Of Biotic Integrity For Lakes In Eastern South Dakota, Daniel T. Nelson

Electronic Theses and Dissertations

The Index of Biotic Integrity (IBI) was developed to summarize the impact of watershed and water quality degradation to biotic communities and help to provide a more complete picture of water quality changes that are not captured in traditional physical and chemical measurements. In 2014, nearly 15% of South Dakota lakes did not meet their designated beneficial uses based on water quality measures but the impacts to the fish communities are unknown. The goal of this study was to develop a fish-based IBI for eastern South Dakota lakes by addressing three specific objectives:
1) Determine whether an IBI could be …

Using Rna Seq To Define Genes And Pathways Affecting Salmonella Vaccine Response In Beef Cattle, Sara Awrahman

Electronic Theses and Dissertations

A Salmonella siderophore receptor and porin (SRP) proteins vaccine is an intervention strategy to control Salmonella burden in cattle. The vaccine works by stimulating immunity to produce antibodies against bacterial SRPs as siderophore molecules play a major role in transporting iron to bacteria. Blocking iron uptake system by antibodies causes death of bacterial cells. The vaccine can also be useful to protect humans against salmonellosis, which causes high rates of illness and death annually, by reducing shedding of Salmonella in the feces of cattle. Though other researchers have evaluated efficacy and immune response of this Salmonella SRP vaccine, genes …

The False Intent-Purpose Distinction In Textualism, Aaron Graham

Electronic Theses and Dissertations

Textualism is the theory of legislative interpretation championed most famously by the late Supreme Court Justice Antonin Scalia. Textualism adopts twin interpretive commitments: (1) the meaning of a legislative text should be discerned by application of long-established canons of construction, the most important of which is that the text means what its words convey; and (2) a legislative text means what it meant at the time it was enacted. This paper examines the first principle, and in particular Scalia and treatise coauthor Bryan A. Garner’s belief that it mandates that judges forswear any consideration of legislative intent. This paper assess …

Object Of Your Rejection: The Symbolic Annihilation And Recuperation Of Queer Identities In Country Music, Lauren Veline

Electronic Theses and Dissertations

This thesis addresses the double-marginalization of white queers living in Bible Belt communities by examining the symbolic annihilation of queer identities in country music. Bible Belt queers face unique obstacles and have different needs than queer communities elsewhere due to the cultural context of their communities. The urban-centric (“metronormative”) standards of queer identity and visibility presented in the media do not translate to their lived experiences. Moreover, while white, non-urban southerners possess a source of popular-media expression through country music, queer identities are noticeably absent. The invisibility of Bible Belt queers in the media perpetuates a cycle of hostility and …

Risk, Reward, And The Role Of Habitat Selection On Community Dynamics In Temporary Ponds, Matthew Robert Pintar

Electronic Theses and Dissertations

The processes that generate patterns of species diversity within and among habitat patches are a fundamental topic of interest in ecology. Traditionally, there was a focus on post-colonization effects such as predation, however, pre-colonization processes, such as habitat selection, are equally important determinants of community structure. In freshwater systems, the lethal effects of dominant predators (particularly fish) are well established, while the transition from permanent to temporary ponds is a defining characteristic. This transition produces distinct communities characterized by organisms with complex life cycles and plastic developmental strategies. This means that many organisms occupying habitat patches arrive there by the …

Understanding Child-Centered Canine Assisted Play Therapy: A Qualitative Collective Case Study, Jennifer Austin-Main

Electronic Theses and Dissertations

Children are often referred to counseling for a multitude of reasons (e.g. divorce, trauma, abuse, etc.). Given these challenges faced by so many children, counselors are charged with using evidence based forms of counseling to appropriately help children and their families address these issues. One highly researched and effective therapeutic intervention to working with children is play therapy, more specifically child-centered play therapy (CCPT). A recent trend in play therapy is the incorporation of animals into the play therapy process to facilitate healing and growth (Chandler, 2012; Parish-Plass, 2013; Thompson, 2009), in particular the use of canines in CCPT, known …

Preparation And Characterization Of Acitretin-Loaded Niosomes For Psoriasis Treatment, Marey Abdulmootani Almaghrabi

Electronic Theses and Dissertations

Psoriasis is a chronic skin disease that manifests as impaired epidermal differentiation. The disease is typically treated with acitretin, an effective oral cytotoxic agent. However, due to its side effects, its use is highly limited. Topical delivery of acitretin may decrease the systemic toxicity and increase the drug’s bioavailability at the pathological site. However, this approach has some limitations. The decrease in skin integrity due to psoriasis could lead to escape of drug into the systemic circulation system and consequently compromise the topical approach. Also, the high instability of acitretin in the presence of heat could limit its topical application. …

A “Human Endeavor”: Killing In Contemporary U.S. Combat Narratives, William Mackenzie

Electronic Theses and Dissertations

This PH.D dissertation aims to develop a 3-D numerical model of dam-break flows on movable beds. Three tasks are defined to accomplish the goal of this study. The first task is developing a 3-D hydrodynamic model to simulate dam-break flow on fixed beds with simple geometry and test the water surface tracking technique. This model solves the Reynolds-averaged Navier-Stokes (RANS) equations using a finite-difference method on rectilinear, staggered grids. The volume-of-fluid (VOF) technique with SOLA-VOF advection scheme is used to capture the free surface motion. The developed model is tested using several experimental dam-break flows and the VOF technique is …

Diplomacy Of Pirates: Foreign Relations And Changes In The Legal Treatment Of Piracy Under Henry Viii, Jamie Deanna Sessions

Electronic Theses and Dissertations

No abstract provided.

Consciousness In Comatose Clowns: No Funny Business, Mary Gregg

Electronic Theses and Dissertations

Consider the tragic case of four circus clowns whose pie-to-the-face gag effectively knocks each one into a cream-pie coma. In each of the four cases, motor capacities (voluntary speech, limb movement, etc.) Are not available to the patient's conscious control. Although none of our apparently comatose clowns have voluntary motor capacities, each has a unique set of internal and external activity going on. In other words, each of our clowns (bozo, chuckles, wiggles, and krusty, respectively), now sits in a vegetative state. Now, there's a problem. Sometimes comatose patients are conscious, so there's a big philosophical and empirical issue going …

Speak'st, Art Sound: The Material Voice In Early Modern England, Nathaniel Philip Likert

Electronic Theses and Dissertations

This thesis argues that early moderns conceived of speech as a material phenomenon; voice struck out from bodies into environments. Early modern voices thus participate in what sound studies scholars call the soundscape, which I link to current new materialist and ecological theories of network and assemblage. Within this soundscape, I pay special attention to the role of language as a semantic system of meaning. Current ecological criticism takes for granted the utter “flatness” of ontology, and as such discards the question of human language so central to previous deconstructive and discursive scholarship. My thesis attempts to account for the …

Structure & Simulation: Growth And Evolution In Generative Music, Dane Filipczak

Electronic Theses and Dissertations

This thesis describes a series of original interactive computer music compositions that are structured around simulations of natural phenomena. The relationship between simulation and music composition is considered and found to be a likely site of high creative potential due to both domains’ concern with process and becoming as opposed to static artifacts. The medium of the web application is considered as an ideal site for contemporary musical experimentation and a portrait is given of the current affordances and constraints of browser-based applications. Five musical systems are described within the context of their simulation and design techniques and some reflections …

Universal Principles Of Bioethics And Patient Rights In Saudi Arabia, Ahmed Abdulbasit Bukhari

Electronic Theses and Dissertations

In order to keep pace with international bioethical practices, and with international bioethical declarations, this dissertation will investigate challenges facing patients’ rights discourse in Saudi Arabia, and the adaptation of universal bioethics standards in the Saudi healthcare system. The role of religion and issues of human rights will be discussed further, given that religion and human rights affect patient’s rights profoundly. Specifically, the divergence between religious dictations and the secular language of human rights principles will provide a distinctive perspective on patients’ rights discourse, especially in a country such as Saudi Arabia where religion is integral to the national foundations, …

Revamping The United States Organ Donation System: An Ethical Justification For Compensated Live Organ Donation, Jordan Potter

Electronic Theses and Dissertations

With over 100,000 Americans currently on organ waiting lists in the United States, the mass shortage of viable organs for transplantation is one of the most pressing healthcare issues that we face as a country today. Thousands of these individuals on organ waiting lists will ultimately die waiting on an organ transplant that will never come. Many differing proposals have been discussed with the aim of increasing organ donation rates and the raw number of organs available for transplant, including changing our default consent status for cadaveric organ donation and the option of incentivizing organ donation by compensating live donors …

Race, Retreat, And Refuge: Black Voices, American Nature Writing, And Ecocritical Exile, Bryon Patrick Williams

Electronic Theses and Dissertations

While existing scholarship has begun to recognize the extensive environmental experience of African Americans during the nineteenth century, black-authored environmental writing from the era is conspicuously scant in studies and anthologies into the present, even in volumes devoted to ecocritically-inflected texts by authors of color. My dissertation argues that contemporary, racially-aligned divides and gaps in environmental discourse have roots in the 1840s and 50s, when the nature writing genre coalesced into its most enduring form in the works of Henry David Thoreau, literary artist turned cultural icon. This key era—during which black Americans were frequently subject to systematic deprivation of …

Trauma And Aggression In Juvenile Offenders, Cassandra M. Berbary

Electronic Theses and Dissertations

Indirect aggression has been found to be more common among females than males and may be an unconsidered contribution to aggression shown in delinquent girls. Although there are no research studies to date that have investigated the link between relational aggression and law violations, there are some studies that have considered indirect and overt aggression in females; however, this research has been largely inconclusive. An additional obstacle for offenders is the presence of previous traumas, which has been closely linked to both overt and indirect aggression. Although both males and females in the juvenile justice system are likely to have …

Refugee-Led Organizations And The Obstacles They Face: A Comparative Study Of Syria Bright Future And The Bhutanese Community Association Of Pittsburgh, Priscila Elizabeth Cordoba Montoya

Electronic Theses and Dissertations

In the nexus of our collective history, it has been recorded that human-induced political and social conflicts play a powerful role in displacing millions of people. The social insecurity produced by conflict persists long after they have ended, as refugees adjust to new circumstances, cope with loss, and attempt to regain a sense of normalcy. This study focuses on two distinct refugee-led organizations, namely a Syrian and a Bhutanese organization. These organizations operate in distinct stages of resettlement, in different parts of the world—one in a state of emergency, the other in resettlement in the United States. However, both organizations …

Impact Of Anti-Viral Immunity On Neural Stem/Progenitor Cell Activity And Implications For Cns Development, Apurva Kulkarni

Electronic Theses and Dissertations

Viral infection and inflammation in the central nervous system (CNS) can cause neuropathology, particularly in the prenatal and neonatal stages. Severe damage to the CNS may result from cytopathic effects of viral infection or from the immune response that may lyse virally-infected cells or release inflammatory mediators to mediate viral clearance. Neural stem/progenitor cells (NPSCs) are multipotent cells in the CNS that are often disrupted by neurotropic viral infections. They may be directly infected by the virus or respond to inflammatory cytokines released from resident as well as infiltrating immune cells. This bystander effect may affect NSPC differentiation and proliferation …

Paul Ricoeur's Hermeneutics Of The Self: Living In The Truth, Fergus James Laughland

Electronic Theses and Dissertations

This dissertation focuses on the relationship of selfhood and ethics from the competing philosophical frameworks developed by Paul Ricoeur and Alain Badiou. Seeking “nothing short of a full victory” on the “battlefield” of history, Badiou argues that Ricoeur deceives his readers by hiding the relationship of the self to history. The purpose of this deception is to defend a definition of history that allows for a Providential sense of history whereby the past could be actively forgotten whereby crimes could be forgiven. In this work I examine Ricoeur’s hermeneutics of the self as developed in Oneself as Another (Soi-même comme …

Phylogeny, Psychology, And The Vicissitudes Of Human Development: The Anxiety Of Atavism, Frank Pittenger

Electronic Theses and Dissertations

This cross-disciplinary dissertation provides a missing intellectual history of an ostensibly dead idea. Once widely held and no less elegant for its obsolescence, the principle of biogenetic recapitulation is best remembered by its defining mantra, “ontogeny recapitulates phylogeny.” Among psychologists and sociologists as well as embryologists, the notion that the development of any individual organism repeats in compressed, miniaturized form the entire history of its species enjoyed broad (if not uncontested) acceptance through the early twentieth century. The author reexamines the origins of this theory in the work of Charles Darwin and Ernst Haeckel, and traces its influence in psychology …

Dna Metabarcoding Reveals Provisioning Of Pollution-Sensitive Aquatic Insects, Resource Partitioning, And Dietary Shifts Among Breeding Neotropical Migratory Songbirds In A Riparian Habitat, Brian K. Trevelline

Electronic Theses and Dissertations

Elucidating the diet of Neotropical migratory birds is essential to our understanding of their ecology and to their long-term conservation. Beyond broad taxonomic or morphological categories, however, the diet of Neotropical migrants is poorly documented. Using the molecular techniques of DNA barcoding and next-generation sequencing, we elucidated the diet of Neotropical migratory songbirds breeding in the riparian zones of headwater Appalachian streams. This approach resulted in a genus- or species-level description of diets that improved the current understanding of how songbirds utilize aquatic prey resources in riparian habitats. Furthermore, our approach revealed that breeding songbirds partition prey resources within a …

Relevant Versus Extraneous Music In Multimedia Instruction: A Study Of The Coherence Principle, Jonathan Gunnell

Electronic Theses and Dissertations

The purpose of this study was to examine whether the inclusion of nonessential music in an instructional multimedia presentation affected learners’ ability to recall information in retention, cued-retention, and transfer cognitive measures. This study tested the coherence principle of multimedia learning which holds that the addition of nonessential content that is not relevant to the instruction is detrimental to learning. This study tested this principle by analyzing differences across three groups; a control group which included no additional music, a group including bland music selected at random, and a group including music that has been intentionally designed to align with …

Hospitality In Communication: Applying The Rule Of Saint Benedict To The Home, Karen Fetter

Electronic Theses and Dissertations

Hospitality is a tradition that has been immersed into all cultures for thousands of years. Philosophically and religiously, it has roots among ancient philosophers and in the Bible. Before the modern technologies and development of the tourism industry, hospitality was found in churches and monasteries. The reciprocal relationship between the host and the stranger give metaphorical meanings to life in general because it is how we treat each other that forms the moral balance in society and gives the human person what is necessary for a healthy and full life. St. Benedict was a man who experienced the benefits of …

Reading The Culture Wars In The New Academic Novel, 1984-Present, Ian Butcher

Electronic Theses and Dissertations

The “new academic novel” emerged in the 1980s as what had previously been a cloistered, insular genre began to engage much more directly with the social and political import of universities and the people who work in them. I argue that an important strand of this development centres on a group of novels that through their depiction of recent developments in academia—the threat of political correctness, the so-called theory wars, the growth of contingent labour, and the elevation of a corporate logic above educational concerns—document the emergence of neoliberalism as the dominant logic of American higher education and the American …

The Neonatal Anti-Viral Response Fails To Control Measles Virus Spread In Neurons Despite Interferon-Gamma Expression And A Th1-Like Cytokine Profile, Priya Ganesan

Electronic Theses and Dissertations

Neonates are highly susceptible to infections in the central nervous system (CNS) and have a greater risk of viral infections and encephalopathies. Neurotropic viral infections can lead to blindness, hearing loss and neurological deficiencies such as cognitive impairment, epilepsy, and even death in the neonatal and pediatric populations. Viral infections also are hypothesized to indirectly contribute to neurodegenerative and neuropsychiatric diseases such as Schizophrenia and Parkinson’s disease later in life due to early neuronal damage or stress. Many diverse viruses are capable of invading the neonatal CNS including Borna Disease Virus, Coxsackievirus (CV), Herpes simplex viruses (HSV), and measles virus. …

Integrated Marketing Communication As Epideictic Rhetoric And Its Implications For Ethical Branding, Tricia Mcfadden

Electronic Theses and Dissertations

Traced to ancient scholarship, rhetoric, and the philosophy of communication and through interpretive perspectives, rhetoric, narrative and ethics have been established grounding of communication and social structures. IMC has emerged as a contemporary genre of epideictic rhetoric with ethical obligations to our postmodern polis. Through the redefining of the branding metaphor within an ethical, grounded and narrative framework, the focus on ethos and connection to the audience through Schrag’s “fitting response” may combat the previous challenges of narrative and marketing and its deconstructive effects. IMC as communicative praxis engages branding discourse in action with texture as the bonding agent between …

Target Based Design And Synthesis Of Fused Pyrimidines In The Potential Treatment Of Cancer And Opportunistic Infection, Khushbu Shah

Electronic Theses and Dissertations

This dissertation describes an introduction, background and research progress in the areas of agents designed as (a) selective Pneumocystis jirovecii dihydrofolate reductase (pjDHFR) inhibitors for pneumocystis pneumonia (PCP) infection; (b) inhibitors of microtubule polymerization and multiple receptor tyrosine kinase (RTK) for potential treatment of cancer; and (c) substrates for tumor-targeted therapy for cancer.

PCP is a host species-specific infection. Most of the drugs, synthesized and evaluated so far, have been tested against Pneumocystis carinii dihydrofolate reductase (the causative organism in rats), which would not necessarily be effective against pjDHFR (the causative organism in humans). Trimethoprim-sulfamethoxazole (TMP-SMX) combination, which has been …

Nitric Oxide Release From Poly(Lactic-Co-Glycolic Acid) Nanoparticles And Titanium Alloy, Nina A. Reger

Electronic Theses and Dissertations

Current methods for the treatment of bacterial infection involve the use of systemic antibiotics, which are high concentrations of antibiotics delivered over a long period time. Unfortunately, the use of systemic antibiotics can cause harmful side effects to the patient and increases the possibility for antibiotic resistance. The delivery of antibiotics or alternative antimicrobial compounds, such as nitric oxide, directly to the site of infection would decrease the amount of antibiotic necessary to treat a bacterial infection.

Poly (lactic-co-glycolic acid)/polyvinyl alcohol nanoparticles and a titanium- aluminum-vanadium metal oxide alloy implant were surface functionalized to deliver nitric oxide. Polymer nanoparticles can …