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Analysis Of Driver Behavior Modeling In Connected Vehicle Safety Systems Through High Fidelity Simulation, Ahura Jami Jan 2018

Analysis Of Driver Behavior Modeling In Connected Vehicle Safety Systems Through High Fidelity Simulation, Ahura Jami

Electronic Theses and Dissertations

A critical aspect of connected vehicle safety analysis is understanding the impact of human behavior on the overall performance of the safety system. Given the variation in human driving behavior and the expectancy for high levels of performance, it is crucial for these systems to be flexible to various driving characteristics. However, design, testing, and evaluation of these active safety systems remain a challenging task, exacerbated by the lack of behavioral data and practical test platforms. Additionally, the need for the operation of these systems in critical and dangerous situations makes the burden of their evaluation very costly and time-consuming. …


Acute And Chronic Vascular Responses To Blood Flow Restriction In The Upper Body, J. Grant Mouser Jan 2018

Acute And Chronic Vascular Responses To Blood Flow Restriction In The Upper Body, J. Grant Mouser

Electronic Theses and Dissertations

Blood flow restriction (BFR) with low load exercise increases muscular size and strength. Little is known of vascular adaptations to this training modality, and nothing was known at very low loads. These studies examined cardiovascular responses to high load (70% of one-repetition maximum (1RM)) and very low load (15%1RM) exercise, alone or at two levels of BFR. Study 1: Participants performed unilateral biceps curls using either 15%1RM with no BFR (15/00), 40% of arterial occlusion pressure (AOP) (15/40), or 80%AOP (15/80), or 70%1RM (70/00). Systolic and diastolic blood pressure (SBP, DBP) and blood flow (BF) were measured in the arms …


Searching Through Debris: A Mass Analysis From The Carter Robinson Mound Site In Lee County, Virginia, Robert Capps Jan 2018

Searching Through Debris: A Mass Analysis From The Carter Robinson Mound Site In Lee County, Virginia, Robert Capps

Electronic Theses and Dissertations

The Mississippian period is one of the most widely studied periods in the prehistoric Southeast, but there are areas such as the Mississippian frontier that have not been explored in great detail. Carter Robinson is a Mississippian chiefdom located on the frontier in southwest Virginia during the thirteenth and fourteenth centuries. To better understand the people living at this site a mass analysis was conducted to examine the lithic debris left behind by the people living there. The purpose of this thesis is to identify the degree of tool production at Carter Robinson and to identify areas of tool production, …


On The Future Of Antidepressant Treatments: Targeting Neurotrophic Factors And Plasticity, Stephen W. White Jan 2018

On The Future Of Antidepressant Treatments: Targeting Neurotrophic Factors And Plasticity, Stephen W. White

Electronic Theses and Dissertations

For 60-plus years the explanatory model for Major Depressive Disorder (MDD) has been the monoamine theory, which states that low levels of monoamine neurotransmitters or alterations in their post-synaptic receptors are responsible for depressive symptoms. Drugs designed to elevate synaptic monoamine levels have remained the first line of pharmacotherapy prescribed by clinicians for MDD patients. However, these drugs have shortcomings. Despite evidence that current antidepressants elevate synaptic monoamine levels within hours of administration, these drugs require four to six weeks of daily administration before symptom relief appears. Furthermore, approximately half of patients taking typical antidepressants never achieve full symptom relief. …


Rapid And Simultaneous Determination Of Nutritional Constituents Of United States Grown Oats Using Near Infrared Reflectance Spectroscopy (Nirs), Devendra Paudel Jan 2018

Rapid And Simultaneous Determination Of Nutritional Constituents Of United States Grown Oats Using Near Infrared Reflectance Spectroscopy (Nirs), Devendra Paudel

Electronic Theses and Dissertations

Oats is a unique cereal owing to its nutritional and health benefits. Near Infrared Reflectance Spectroscopy (NIRS) is an efficient tool for monitoring the quality of cereal foods. NIRS holds potential for non-destructive multicomponent oat analyses with advantage of large sample throughput, speed, and reduced cost. The purpose of this study was to develop predictive calibration models for estimating beta-glucan, protein, and oil content of US oat cultivars using NIRS and validated AACCI reference methods. A rapid, non-destructive (whole oat groat), and secondary NIRS method was developed to estimate beta-glucan, protein, and oil content based on the standard reference analyses …


Synthesis And Evaluation Of Dual-Acting Ligands For Mu Opioid And Neuropeptide Ff Receptors, Kelsey Gabrielle Mcpherson Jan 2018

Synthesis And Evaluation Of Dual-Acting Ligands For Mu Opioid And Neuropeptide Ff Receptors, Kelsey Gabrielle Mcpherson

Electronic Theses and Dissertations

Pain, although subjective, is an unpleasant sensation caused by a noxious stimulus, that effects millions of people every year. Currently, the most frequently prescribed class of analgesics for moderate to severe acute and sometime chronic pain are opioid analgesics, most commonly ?-opioid receptor (MOP) agonists, such as oxycodone, morphine, and fentanyl. Although these drugs provide significant pain relief, they are also associated with unwelcome side effects such as constipation, addiction, physical dependence, respiratory depression, and physiological tolerance that leads to hyperalgesia. Receptor desensitization due to excessive receptor activation by an agonist is but one source of physiological tolerance; it can …


Counter Clockwise Culture Shock, Matthew Mercer Jan 2018

Counter Clockwise Culture Shock, Matthew Mercer

Electronic Theses and Dissertations

Counter Clockwise Culture Shock is a memoir focused the narrator's return to his hometown, a place he barely escaped: drug addiction, incarceration, bad relationships, alienation, an Oedipal mother, and suicidal threats. It is reflection on both culture and self, after I gained an outside perspective from Japan. The narrator is forced to relive nihilism and monotony, and face the troubles of his younger years. It describes the difficult journey of today's youth, in an evermore technologically dynamic world - with few role models able to plot a course through. This is a meditation on past actions that ended in survival. …


Behavioral And Disease Ecology Of Gopher Tortoises (Gopherus Polyphemus) Post Exclusion And Relocation With A Novel Approach To Homing Determination, Johnathan Napier Jan 2018

Behavioral And Disease Ecology Of Gopher Tortoises (Gopherus Polyphemus) Post Exclusion And Relocation With A Novel Approach To Homing Determination, Johnathan Napier

Electronic Theses and Dissertations

In the wake of human expansion, relocations and the loss of habitat can be stressful to an organism, plausibly leading to population declines. The gopher tortoise (Gopherus polyphemus) is a keystone species that constructs burrows it shares with 362 commensal species. Frequent exclusions and relocations and long generation times have contributed to G. polyphemus being State-designated as Threatened in Florida. Prior studies have indicated that G. polyphemus may possess homing behavior and thus be able to counteract stressors due to relocation and exclusion. I radiotracked a cohort of G. polyphemus for 11 months following excavation, relocation, and exclusion due to …


Raça, Jinshu, Race: Whiteness, Japanese-Ness, And Resistance In Sūkyō Mahikari In The Brazilian Amazon, Moana Luri De Almeida Jan 2018

Raça, Jinshu, Race: Whiteness, Japanese-Ness, And Resistance In Sūkyō Mahikari In The Brazilian Amazon, Moana Luri De Almeida

Electronic Theses and Dissertations

This dissertation presented an analysis of how leaders and adherents of a Japanese religion called Sūkyō Mahikari understand and interpret jinshu (race) and hito(person) in a particular way, and how this ideology is practiced in the city of Belém, in the Brazilian Amazon. The teachings of Sūkyō Mahikari classify humanity into five races (yellow, white, red, blue/green, black/purple) and five religions (Christianity, Islam, Buddhism, Confucianism, Taoism). In this classification, the original humans - hito, the kingly race ōbito, and the God-given supra-religion sūkyō - deteriorated into ningen (people), the other races, and shūkyō (religions) along an …


Biomechanical Characterization Of Video-Recorded Short-Distance Falls Involving Children Equipped With A Biometric Device: A Pilot Study., Bret A Hilt Jan 2018

Biomechanical Characterization Of Video-Recorded Short-Distance Falls Involving Children Equipped With A Biometric Device: A Pilot Study., Bret A Hilt

Electronic Theses and Dissertations

Falls are commonly used as a false history by caregivers to conceal child abuse. Determining biomechanical compatibility is a key aspect in differentiating abuse from accident. Current forensic approaches are limited in assessing biomechanical compatibility of short-distance falls involving children due to a lack of reliable witnessed falls with known injury outcomes. The goals of this pilot study were to characterize biomechanical measures and to examine differences in biomechanical measures based on child and fall characteristics in reliable witnessed video-recorded falls involving children. The results of this study will serve as preliminary data for an on-going larger study with the …


Restoring Cholesterol Homeostasis In Familial Hypercholesterolemia Cell Line Model, Lubna Hindi Jan 2018

Restoring Cholesterol Homeostasis In Familial Hypercholesterolemia Cell Line Model, Lubna Hindi

Electronic Theses and Dissertations

Familial hypercholesterolemia (FH) is an autosomal dominant disorder that results in elevated levels of low-density lipoprotein cholesterol (LDL-C). This increase in serum cholesterol level has been shown to result in premature coronary artery disease (CAD) with devastating symptoms from a young age. Today, the prevalence of heterozygous FH (HeFH) and homozygous FH (HoFH) is estimated to be 1 in 320 and 1 in 160,000 people, respectively. FH is referred to as an underdiagnosed disease due to the large number of mutations that continues to grow. These mutations often exist in one of or a combination of three genes: low-density lipoprotein …


Optimization Of Plga And Plga-Dasatinib Particles Through A Taguchi Design Approach, Rayeanne N Balgemann Jan 2018

Optimization Of Plga And Plga-Dasatinib Particles Through A Taguchi Design Approach, Rayeanne N Balgemann

Electronic Theses and Dissertations

Proliferative vitreoretinopathy (PVR) is a disease of the retina in the human eye. Retinal pigment epithelium cells (RPE) undergo an epithelial to mesenchymal transition in response to retinal trauma. This transition gives the cells mobility and allows them to potentially infiltrate the vitreous chamber and deposit on either side of the retina. Once cell deposition has occurred, along with several other transformed cells derived from cell types such as Müller glia, these migratory cells can form a membrane contiguous with the retinal extracellular matrix and, upon contraction, cause wrinkling of the retina. If left untreated PVR can lead to traction …


Narrative Transportation And Virtual Reality: Exploring The Immersive Qualities Of Social Justice In The Digital World, Sara Raffel Jan 2018

Narrative Transportation And Virtual Reality: Exploring The Immersive Qualities Of Social Justice In The Digital World, Sara Raffel

Electronic Theses and Dissertations

This dissertation explores the potential applications for virtual reality (VR) stories in support of social justice causes, examining whether digital games historically been successfully leveraged for social justice purposes, and determining which components of VR technology can most encourage narrative transportation of participants in VR stories. The first chapter examines theories of simulation, virtual reality, narrative, and interactivity, as well as concepts of immersion from various disciplines and settles on narrative transportation, a theory from cognitive psychology, as the most useful in measuring the effect of VR stories on participants. The second chapter examines ethnographic practices, activist games, and modes …


A Multisystem Approach For The Characterization Of Bacteria For Sustainable Agriculture, Briana Lee Jan 2018

A Multisystem Approach For The Characterization Of Bacteria For Sustainable Agriculture, Briana Lee

Electronic Theses and Dissertations

The chemical, physical, and biological properties of bacteria developing resistance have been explored in animal based bacteria while plant bacteria have been largely neglected. Thus, the ability to probe changes in stiffness, adhesion, binding interactions and molecular traits of bacteria causing plant diseases is of great interest to develop a new generation of more potent, yet sustainable, pesticides. Our study aims to investigate the physical and chemical properties of bacterial systems, in particular their cell walls. Building upon this fundamental understanding of the cells, we also investigate the physicochemical responses associated to multivalent nanoparticle-based bactericide treatments on bacterial systems identified …


Seeing Living Things: Observations Of Figures From The Outside In, Forrest Deblois Jan 2018

Seeing Living Things: Observations Of Figures From The Outside In, Forrest Deblois

Electronic Theses and Dissertations

This writing accompanies the outcomes of my studio practice over the last three years, focusing on two bodies of work of paintings and drawings. In it I describe and analyze multiple influences tied to the progression and change in my studio practice. I began the process of my work with images and subjects from my home state of Florida, frequently juxtaposing the wildlife and humans, now I see this pattern as a byproduct of a studio practice functioning as a introspective reflection of what I experience, the things that I understand and the things that I don't. I deconstruct elements …


Investigations Of Possible Cases Of Scurvy In Juveniles From The Kellis 2 Cemetery In The Dakhleh Oasis, Egypt, Through Stable Carbon And Nitrogen Isotopic Analysis Of Multiple Tissues, Georgina Chasse Jan 2018

Investigations Of Possible Cases Of Scurvy In Juveniles From The Kellis 2 Cemetery In The Dakhleh Oasis, Egypt, Through Stable Carbon And Nitrogen Isotopic Analysis Of Multiple Tissues, Georgina Chasse

Electronic Theses and Dissertations

Vitamin C deficiency, or scurvy, is a disease that can occur in humans at any age and has been seen throughout time. Scurvy affects the production of connective tissues, including collagen, which leads to the many symptoms of the disease, including fatigue, anemia, bleeding gums and lost teeth, skeletal changes, and even death. The Kellis 2 cemetery in the Dakhleh Oasis, Egypt, in use from approximately AD 50-360, contains the remains of many juveniles who exhibit skeletal indicators of scurvy. Tissue samples from juveniles who did (n=31) and did not (n=117) exhibit skeletal indicators of scurvy were analyzed isotopically, with …


Freedom At The Freak Show: Carnivalesque Imagery In The Fiction Of Eudora Welty, Flannery O'Connor And Katherine Anne Porter, Virginia Mccarley Jan 2018

Freedom At The Freak Show: Carnivalesque Imagery In The Fiction Of Eudora Welty, Flannery O'Connor And Katherine Anne Porter, Virginia Mccarley

Electronic Theses and Dissertations

This thesis examines the function of the circus and the sideshow in the work of Eudora Welty, Flannery O’Connor, and Katherine Anne Porter, arguing that all of these authors employ Mikhail Bakhtin’s idea of the carnivalesque as a reaction to and against the expectations put on them as women who are pressured to conform to the Southern ideal. In the first chapter, I argue that Eudora Welty uses the carnivalesque to reveal the performativity of normalcy in both “Lily Daw and the Three Ladies” (1937) and “A Memory” (1937). These performances, in the first story particularly, offer a critique of …


Preparation And Evaluation Of Valacyclovir Hydrochloride Ocular Inserts By Hot Melt Extrusion Technique, Gauri Shadambikar Jan 2018

Preparation And Evaluation Of Valacyclovir Hydrochloride Ocular Inserts By Hot Melt Extrusion Technique, Gauri Shadambikar

Electronic Theses and Dissertations

The objective of the current study was to investigate the processability of Hot Melt Extrusion to formulate Ocular Inserts of Valacyclovir Hydrochloride and Evaluate its drug release in vitro and in vivo. Valacyclovir is the prodrug of Acyclovir, which is used in treatment of ocular keratitis and HSV infections. The bioavailability of the prodrug is better than the acyclovir and it is proved to permeate extensively through the corneal barrier. The polymer of choice was Klucel® Pharm MF and JF grades for the study. To optimize the formulation, different physical mixtures of the polymers and plasticizers (PEG 400 and Propylene …


Characterizing Variable Flow Pathways And Geochemical History Of Seepage Under The Mississippi River Levee: 2011, 2015, And 2016 Floods, Kaitlin Marie Voll Jan 2018

Characterizing Variable Flow Pathways And Geochemical History Of Seepage Under The Mississippi River Levee: 2011, 2015, And 2016 Floods, Kaitlin Marie Voll

Electronic Theses and Dissertations

Seepage beneath levees during flood stage becomes a concern when piping occurs, creating channels beneath the levee and forming sand boils where transported sediments discharge. Along the lower Mississippi River, pathways beneath the levee vary with surface geology, following deeper paths where the levee overlies channel fill deposits, and shallower paths where it overlies sand bar deposits. A preliminary investigation north of Vicksburg, MS, during the 2011 flood, demonstrated the potential for using aqueous geochemistry to differentiate sand boils forming at the end of deep and shallow flow pathways, though the study was limited to cation and trace metal analyses. …


Down Under Punks And Dixie Rock: Reflections On Making The Documentary Film Chinese Whispers - Southern Roots In The Australian Swampy Sound, Gretchen Labudde Wood Jan 2018

Down Under Punks And Dixie Rock: Reflections On Making The Documentary Film Chinese Whispers - Southern Roots In The Australian Swampy Sound, Gretchen Labudde Wood

Electronic Theses and Dissertations

No abstract provided.


Throne Of Fans: Examining The Roles Of Feminism, Platform And Community In An Online Fandom, Sarah Leiser Jan 2018

Throne Of Fans: Examining The Roles Of Feminism, Platform And Community In An Online Fandom, Sarah Leiser

Electronic Theses and Dissertations

This thesis involves examining the influence of feminism, platform and community on the fandom of Sarah J Maas (SJM) novels on the social network site Tumblr. The goals are to show how a shift to an open social network site has changed the practice of fandom and how various feminisms are applied to popular culture and learned through Tumblr. An ethnographic study and textual analysis on SJM fandom posts and interactions on Tumblr were utilized in order to reach these goals. The observations and analysis examines the data in three categories: the established characteristics of fandom on Tumblr, the characteristics …


Measuring The Influence Of Bedding On Soil Nitrogen Losses And Corn Crop Nitrogen Characteristics For Fall Applied Solid Beef Cattle Manure In Eastern South Dakota, Mukesh Mehata Jan 2018

Measuring The Influence Of Bedding On Soil Nitrogen Losses And Corn Crop Nitrogen Characteristics For Fall Applied Solid Beef Cattle Manure In Eastern South Dakota, Mukesh Mehata

Electronic Theses and Dissertations

Nitrogen (N) is a major component of chlorophyll which plays a key role in the photosynthesis process in crops. The N is one of the highest demanded nutrients by all plants for their growth and reproduction. Manure or inorganic fertilizer is often applied to fulfill the crops’ N demand. However, the applied N sources have the potential of N losses in different forms from the soil volume in many ways such as ammonia (NH3) volatilization, aerial nitrous oxide (N2O) loss, nitrate (NO3 --N) leaching, and runoff and/or erosion. Soil fertility, crop yield, water quality, and …


Evaluating E. Coli Particle Attachment And The Impact On Transport During High Flows, Louis Amegbletor Jan 2018

Evaluating E. Coli Particle Attachment And The Impact On Transport During High Flows, Louis Amegbletor

Electronic Theses and Dissertations

Fecal indicator bacteria, including E. coli, are the leading cause of water quality impairments within assessed waters in the United States. The source of E. coli includes WWTP, leaking sewers, animal manure, wildlife, livestock, and stream bed sediment. Storm events contribute to bacteria loading within waters through wash-in of land sources of bacteria and resuspension of bacteria within sediments. Bacteria introduced into the water column are either attached to particles or are unattached (or free-living). The goal of this study was to examine the attachment of E. coli to different particle sizes, including their impact on contributing to water …


Role Of Brain Derived Neurotrophic Factor (Bdnf) In Stimulating Strength Improvements Induced By Short-Term Resistance Training, David Church Jan 2018

Role Of Brain Derived Neurotrophic Factor (Bdnf) In Stimulating Strength Improvements Induced By Short-Term Resistance Training, David Church

Electronic Theses and Dissertations

Strength adaptations from short-term resistance training are thought to be related primarily to neurological adaptations. Considering brain-derived neurotrophic factor (BDNF) role in the nervous system, it is possible that BDNF has a role in these adaptations. Fourteen untrained males were randomized into either a resistance training (RT; n =8) or control (CON; n=6) group. Motor unit (MU) recruitment at 50% and 80% of each participant's maximal voluntary isometric contraction (MVIC), muscle cross sectional area (CSA) and thickness (MT), as well as one-repetition maximum (1RM) of the squat (SQT), leg press (LP), and leg extension (LE) were performed before (PRE) and …


Broken Toys, Robin Eliot Jan 2018

Broken Toys, Robin Eliot

Electronic Theses and Dissertations

This novel is about a character, Felicity Gourd. She's Cinderella, but she lives in twenty-first century Boston and knows the Cinderella story as well as anyone else. She's also one of a small number of people who are able turn into the creatures represented by their childhood toys. Felicity's toy was a mouse. Her godmother's was, of course, a fairy. Through her godmother, Felicity enters the community of Toys, where she finally finds a home. But the Toys are the only people who stand in the way of Clarity, a secret organization that wants to place humanity under the rule …


Dynamically Tunable Plasmonic Structural Color, Daniel Franklin Jan 2018

Dynamically Tunable Plasmonic Structural Color, Daniel Franklin

Electronic Theses and Dissertations

Functional surfaces which can control light across the electromagnetic spectrum are highly desirable. With the aid of advanced modeling and fabrication techniques, researchers have demonstrated surfaces with near arbitrary tailoring of reflected/transmitted amplitude, phase and polarization - the applications for which are diverse as light itself. These systems often comprise of structured metals and dielectrics that, when combined, manifest resonances dependent on structural dimensions. This attribute provides a convenient and direct path to arbitrarily engineer the surface's optical characteristics across many electromagnetic regimes. But while many of these plasmonic systems struggle to compete with the efficiency of pre-existing technologies, the …


Neuromuscular Junction Defects In A Mouse Model Of Charcot-Marie-Tooth Disease Type 2o, Thywill Sabblah Jan 2018

Neuromuscular Junction Defects In A Mouse Model Of Charcot-Marie-Tooth Disease Type 2o, Thywill Sabblah

Electronic Theses and Dissertations

Charcot Marie Tooth disease (CMT) represents the most common inheritable peripheral group of motor and sensory disorders; affecting 1 in 2500 people worldwide. Individuals with CMT experience slow progressing weakness of the muscle, atrophy, mild loss of motor coordination and in some cases loss of sensory function in the hands and feet which could ultimately affect mobility. Dynein is an essential molecular motor that functions to transport cargos in all cells. A point mutation in the dynein heavy chain was discovered to cause CMT disease in humans, specifically CMT type 2O. We generated a knock-in mouse model bearing the same …


Pg-Vtv Biogenesis Requires Atp To Facilitate Phosphorylation Of Syntaxin 17, Anika Saxena Jan 2018

Pg-Vtv Biogenesis Requires Atp To Facilitate Phosphorylation Of Syntaxin 17, Anika Saxena

Electronic Theses and Dissertations

The uptake of cytotoxic free fatty acids (FFA) and their conversion to physiologically expedient triglycerides (TAG) which are later on assimilated to very low density lipoproteins (VLDL) is of utmost value among the multifarious tasks performed by the liver. Inflated concentration of VLDL in the blood stream directly correlates with the reinforcement of atherosclerosis. VLDL is synthesized in the hepatic endoplasmic reticulum (ER) and transported to the Golgi where it encounters several alterations. It is then enclosed in distinct post-Golgi VLDL transport vesicles (PG-VTVs) and released into the blood. The data generated in our lab has proved the requirement of …


Touching The Unreal: The Definition, Narrative Strategies, And Aesthetics Of 3d Cartoon Narratives., Nathan Snow Jan 2018

Touching The Unreal: The Definition, Narrative Strategies, And Aesthetics Of 3d Cartoon Narratives., Nathan Snow

Electronic Theses and Dissertations

"Touching the Unreal" follows the structure set out by Scott McCloud in Understanding Comics to argue that understanding cartoons is serious business and requires that we define the art form, outline its basic tenets, and theorize how the mind understands it. The dissertation argues for a new definition of 3D computer generated cartoons, beginning with the most basic definition applicable to all forms of animation and taking into account new technological developments before arriving at the 3D cartoon narratives of today. The dissertation outlines the basic facets of 3D cartoon narratives in terms of narrative and aesthetics, arguing that, in …


Whetting Their Appetite: A Spatial Analysis Of Seasonal Flooding And Raised Field Agriculture In The Llanos De Mojos, Bolivia, Samuel A. Martin Jan 2018

Whetting Their Appetite: A Spatial Analysis Of Seasonal Flooding And Raised Field Agriculture In The Llanos De Mojos, Bolivia, Samuel A. Martin

Electronic Theses and Dissertations

The Llanos de Mojos, a region of the southwestern Amazon, is a seasonally flooded savannah located in the Beni department of Bolivia. The area sustained a significant pre-Columbian population up to the arrival of Jesuit missionaries in the late 17th century. Local communities constructed agricultural landscape modifications to help cultivate crops such as maize, manioc, and sweet potato. Raised fields contributed to soil nutrient intensification and helped to manage flooding. This study examines the relationship between 40,766 raised agricultural fields which were digitized by the Proyecto SIG Arqueologico del Beni using Google Earth and maps of surface flood coverage. Flood …