Suture-Less Trocar Site Closure Clip, Hares A. Patel

Electronic Theses and Dissertations

Introduction: Following laparoscopic surgery, there is a need, in many cases, to close trocar sites to prevent hernias. Currently, devices that exist on the market are suture based, but the lack of standardization in the suturing techniques together with the time-consuming nature of the procedure leads to the need for improvement in trocar site closure products. Trocar closure sites do not need to be fully closed on the fascial layer; rather, sufficiently blocking the hole at the abdominal wall can significantly reduce post-operative herniation. A retrospective study on trocar site herniation (TSH) after laparoscopic surgery indicates a TSH incidence …

Nano-Biophysical Approaches For Assessing Nanoparticle Interactions With Biological Systems, Zachary Untracht

Electronic Theses and Dissertations

Understanding interactions between nanoparticles and biological systems is fundamental for the development of emerging nano-biotechnology applications. In this thesis, I present an investigation of zinc oxide (ZnO) nanoparticles interactions with biomolecules in two separate studies. The first section of my thesis covers tracking and detection of ZnO nanoparticles using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). ZinkicideTM is a bactericidal ZnO nanoparticle which has been developed for agriculture. The characterization of Zinkicide in biological media and in solution has been difficult due to its high dispersibility and ultra-small size. SDS-PAGE is considered a golden standard for protein qualitative interpretations. In …

Let's Take A Selfie! Living In A Snapchat Beauty Filtered World:The Impact It Has On Women's Beauty Perceptions, Angelina Cruz

Electronic Theses and Dissertations

Snapchat's beauty filters have become a prominent force in the social media realm. It's vital in understanding the impact in how Snapchat's beauty filters shape beauty standards among young women. This became the primary motivation of conducting this qualitative study. Six focus groups were conducted to explore the depths of why female college students between the ages of 18-25 decide to post either selfies with Snapchat's beauty filters applied or natural images. Dialectical tensions theory was used as the foundation for this study to explore both the internal and external discursive struggles young women face when deciding to post natural …

The Influence Of Preovulatory Estradiol On Uterine Transcriptomics And Proteomics Around Maternal Recognition Of Pregnancy In Beef Cattle, Emmalee J. Northrop

Electronic Theses and Dissertations

Preovulatory estradiol has been reported to play a crucial role in pregnancy establishment and maintenance, but the mechanism by which estradiol exerts its effects has not been well characterized. Specifically, the interactions between the maternal uterine environment and the developing conceptus can greatly impact pregnancy success or loss. The objective of this dissertation is to determine the effects of preovulatory estradiol exposure on uterine and trophectoderm transcriptomes, and uterine luminal fluid (ULF) protein composition. Beef cows/heifers were synchronized, artificially inseminated (d 0), and grouped into either high (highE2) or low (lowE2) preovulatory estradiol. Uteri were flushed to collect d16 conceptuses …

Assisted Living: Stories, Donovan Swift

Electronic Theses and Dissertations

Assisted Living is a collection of stories that explores themes of parenthood, brotherhood, old and new love, adultery, financial strife, and the many faces of loss. The collection offers different points of view, which allow the reader to experience these themes within varying lives and situations. For example, the eponymous "Assisted Living" is from the perspective of a pet-sitter at the brink of losing both her job and husband, while "Holy Mother" explores the point of view of a wife coming to terms with her affair and the physical injury that has changed her husband. "The World of Reptiles" follows …

The Poems You Don't Own, Emma Reinhardt

Electronic Theses and Dissertations

The Poems You Don't Own is a collection of poems whose speakers explore the journey from the simplistic perspective of childhood to the confusion of adolescence to the first experiences of sexuality, heartbreak, and grief, examining the religious, societal, and gender expectations that influence those experiences. The collection's reverse-chronological order allows readers to travel back through the many experiences that shape a present moment. In poems such as "The Game of Life," the speaker considers the gender roles that begin to influence our perception of relationships from a young age, while poems such as "What to Know Before Writing about …

The Knitting Witch, Katherine Ervin

Electronic Theses and Dissertations

Dangerous, magical women live in a world which explores queerness and antagonistic female relationships against the backdrop of Midwestern crafting culture. Craft magic is beauty and cruelty entwined, a perfect tool for witches to use against each other. After her mother is murdered, the eponymous knitting witch inherits a kidnapping and extortion ring, the victims sewn into enchanted quilts and hidden. With her mother dead, political squabbles consume the knitting witch's coven and rival magical families put pressure on her to give up the quilts, including the dangerous Ma family, whose daughter the knitting witch loves. The knitting witch must …

Divergence Of Threespine Stickleback That Differ In Nuptial Coloration, Clara Sophie Jenck

Electronic Theses and Dissertations

Recent research has led to a much better understanding of the evolutionary processes that mold and structure variation within and among populations. How populations diverge at the genome-wide level and how polymorphism is maintained within a species, however, remains unclear. We address these questions with two freshwater color morphs, red and black, of the threespine stickleback fish (Gasterosteus aculeatus) from the northwest United States, in which a shift from red to black nuptial coloration occurred in several locations following glacial retreat. We measured phenotypic variation in a suite of traits and used next generation sequencing to characterize within-species and among-morph …

"Ocular Proof": Race, Religion, And Gender In The Merchant Of Venice And Othello, Edward A. Cooper

Electronic Theses and Dissertations

This project is a study of the development of early modern racial categories in England - focusing on religion and skin color as primary modes of demarcation interwoven with other prevalent categories of language, ancestry/blood, nationality, and gender - as illuminated in William Shakespeare's The Merchant of Venice and Othello. Religion and skin color, then, are the primary modes of racializing individuals in early modern England and characters in Shakespeare's works. This essay studies the context of racial difference as present in English and European rhetoric, art, theater, and exploration. Given this context, the paper explores the poetic geography …

Amelioration Of Alzheimer's Disease Pathology In 12-Month-Old Happ(Sweind) Transgenic Mice After Treatment With A Cysteine Rich Whey Supplement, Immunocal®, Srivalli Puttagunta

Electronic Theses and Dissertations

Deficits in Reelin expression and signaling play a pathogenic role in Alzheimer’s disease (AD). Thus, strategies aimed at correcting Reelin deficits may provide a novel therapeutic approach to treating AD. The cysteine-rich, whey protein supplement, Immunocal®, has recently been shown to rescue Reelin expression in a mouse model of Schizophrenia. Given that Reelin-expressing neurons of the entorhinal cortex region are a highly vulnerable population of cells that are lost early in AD, we examined the effects of Immunocal® in the hippocampal-entorhinal cortex formation in a mouse model of AD. Glutathione levels and Reelin expression in the hippocampal-entorhinal cortex formation (entorhinal …

Affect And Critique: Negative Dialectics And Massumi's Politics Of Affect, Heidi Ann Rhodes

Electronic Theses and Dissertations

Brian Massumi's concept of affect offers a model of change that relies on sensory-affective modes of resistance to neoliberal power relations. Influenced by Bergson's concepts of time and space, Massumi develops an account of perception as the capacity to entrain with ontological, affective flows of becoming before they are captured and reduced to quantifiable forms. This requires a radical reconfiguration of the body as a zone of indetermination between the virtual field of unformed potentialities and the realm of determined existence. I argue that affect theory cannot fulfill its promise to open new political possibilities without the negativity of critique …

Development And Characterization Of An Inexpensive Single-Particle Fluorescence Spectrometer For Detection And Classification Of Pollen And Other Bioaerosols, Benjamin E. Swanson

Electronic Theses and Dissertations

Atmospheric aerosols are ubiquitous throughout the Earth’s atmosphere and can be important with respect to environmental systems and human health. Pollen particles are a class of primary biological aerosol particles (PBAPs) that cost the United States billions of dollars a year in loss of productivity and healthcare costs due to allergy and respiratory effects. Traditional methods of pollen detection rely on collection and subsequent identification by visual microscopy, yet few measurement stations exist in the United States. As such, current pollen forecasting models have relatively high prediction uncertainty, especially in regions without sampling stations. Recently, laser-induced fluorescence instrumentation has been …

The Size Of The Multiplier: Comparing Alternate Views After The Great Recession, Daniel Focht

Electronic Theses and Dissertations

This thesis reviews the major theoretical frameworks and their outlook on the government spending, its effectiveness, the implied size of the multiplier and how they differed in empirical studies. This is followed by an estimation of the government multiplier for the major U.S. fiscal policy, namely the American Recovery and Reinvestment Act (ARRA), after the Great Recession of 2007-2009. Own estimation of the size of the multiplier is presented using a standard SVAR model based on New Keynesian approach for time period between 2009 and 2018. In addition, following the classical economic theory, the multiplier is recalculated in the absence …

American Converts To Islam, Post-Conversion Experiences Post 9/11, Muhammad Abdelhakam Kolila

Electronic Theses and Dissertations

American converts to Islam and their post-conversion experiences do not attract the attention of many researchers and policy makers in the United States. They have been understudied or overlooked as they are positioned at the margins of studies of Islam and in Muslim communities in the US. Interest in and attention to converts to Islam, however, is triggered once a few embrace an extreme worldview, especially if they join a terrorist group. Therefore, this research intends to add the complexity and diversity of post-conversion experiences of American converts to Islam to the literature of conversion to Islam studies in the …

An Hgis Approach To Land-Use/Land-Cover Change In The Blanice Watershed, Czech Republic, Kelly J. Measom

Electronic Theses and Dissertations

In the South Bohemian region of the Czech Republic, the landscape is distinguished by a network of long narrow fields bordered by hedgerows clustered in small groups. These unique clusters of hedgerows have been interacting with their environment, effectively mitigating erosion, since they were first established in the High Middle Ages. In this research project I used historical maps to characterize land-use and land-cover (LULC) change relating to hedgerow features in one cadastral territory in the Blanice Watershed. Using georeferenced historical maps from 1837 and 1952, and unreferenced historical maps from 1837 to 1953, I compared the historical LULC to …

The Effect Of Conspecific Cues And Neighborhood Effects On Bee Foraging Behavior, Eva Sofia Horna Lowell

Electronic Theses and Dissertations

Foraging bees use social information (e.g. presence of absence of other bees) to assess the quality of flowers when choosing a flower to visit. My research tests how bees choose to visit a particular flower once they have been recruited to a flower patch. I tested if neighborhood effects, or the relative number of bees on neighboring flowers compared to a focal flower, affected to which flower a foraging honey bee visited. I also conducted a meta-analysis to test whether bees in the super-family Apoidae are more likely to visit a flower occupied by a con- or heterospecific bee or …

The Medieval Borderland: Geophysical Analysis Of A Later Medieval Deserted Settlement And Cultural Landscape From Western Ireland, Andrew Ryan Bair

Electronic Theses and Dissertations

This thesis investigates the archaeological remnants of an early 14th century settlement at Ballintober, Roscommon County, Ireland. An innovative methodology combining ground-penetrating radar, magnetic gradiometry, and archaeological excavations is utilized to reconstruct the medieval built environment, which was comprised of a masonry castle, nucleated settlement and wider arable agricultural landscape. By integrating the archaeological and historical records, I pose hypotheses related to the differential statuses of people at the settlement, their domestic and agricultural practices, and a timeline of their occupation and abandonment of the site. The Ballintober settlement offers a unique case study to investigate the colonial dynamics of …

Storytelling And Self In Public Broadcast: A Visual Ethnography Of Rocky Mountain Pbs, Emily Baker

Electronic Theses and Dissertations

Embodied storytelling in Denver's public broadcast media establishes how the intersectional identities of storytellers influence narrative practices in Denver's public sphere. Five approaches to communicating identity informed my theoretical background: embodiment, visual anthropology, the public sphere, practice theory, and phenomenology. Rocky Mountain PBS, a 60-year-old broadcast institution, served as my research site during the summer of 2018. In my thesis, I overviewed the history of RMPBS and observations of production activities performed by the creators of the show Colorado Memories. Using a phenomenological methodology, the research design and data collection included filmed participant observations, semi-structured interviews guided by a …

Characterization Of Vps41 And Its Role In The Regulated Secretory Pathway, Christian Henry Burns

Electronic Theses and Dissertations

Insulin secretory granules (SGs) mediate the regulated secretion of insulin, which is essential for glucose homeostasis. The basic machinery responsible for this regulated exocytosis consists of specific membrane proteins present both at the plasma membrane and on insulin SGs. The protein composition of insulin SGs thus dictates their release properties, yet the mechanisms controlling insulin SG formation, which determines this molecular composition, remain poorly understood. VPS41, a component of the endolysosomal tethering HOPS complex, was recently identified as a cytosolic factor involved in the formation of neuroendocrine/neuronal granules. We now find that a stable pool of VPS41 exists outside of …

Anti-Fat Bias And Attentional Capture, Larissa Catherine Miller

Electronic Theses and Dissertations

Explicitly-rated anti-fat attitudes are correlated with weight-based discrimination, which is rampant in society today as many countries grapple with soaring rates of obesity. Early perceptual processes, such as conscious awareness and visual attention, may be biased based on the weight of the perceived or the perceiver, or any number of individual perceiver characteristics regarding weight-biased attitudes and experiences. The three experiments presented used continuous-flash suppression (CFS) to mask body stimuli, thereby hoping to gain insight into attentional capture of unseen images and its relation to anti-fat attitudes. The pattern of findings in the three experiments presented suggest that what makes …

Integration And Segmentation Conflict During Ensemble Coding Of Aspect Ratio, Elric Matthew Elias

Electronic Theses and Dissertations

The visual system often integrates information that "goes together". Once information has been integrated, summary information (e.g., average emotion or average size) can be extracted; this occurs during ensemble coding. Integration thus allows for fast and efficient generalizations about sets to be made. In contrast, the visual system sometimes segments input that does not go together. For example, the perception of objects can be exaggerated away from natural category boundaries (e.g., a perfect circle is a category boundary; it is neither "flat" nor "tall"). Segmentation allows the visual system to make quick categorical distinctions. Much of the time, integration …

Proximate And Ultimate Consequences Of Stressed-Induced Maternal, Paternal, And Joint Parental Effects In A Changing World, Whitley Rayen Lehto

Electronic Theses and Dissertations

Parental experience can alter the developmental and rearing environments of offspring, resulting in parental effects on offspring traits. I addressed the consequences of stress-induced maternal, paternal, and joint parental effects from both ultimate (ecological/evolutionary) and proximate (physiological/epigenetic) perspectives. I used a full-factorial design in which threespine stickleback (Gasterosteus aculeatus) mothers, fathers, both, or neither were exposed to a model predator at developmentally appropriate times to test for predator-induced maternal, paternal, and joint parental effects on daughters’ mating behavior and egg glucocorticoids (stress hormones) and on offspring gene expression. Maternal and paternal predator exposure independently yielded daughters who preferred …

Stigma In The Post Crisis Age: External Barriers To Accessing Hiv Treatment, Internalized Trauma, And Strategies Of Support In Orlando, Florida, Julian Cerrell Nilsson

Electronic Theses and Dissertations

In 2017, The CDC (center for disease control and prevention) released a memo confirming popular medical opinion that an HIV positive person with an undetectable viral load was unable to transmit the HIV virus. While treatment and prevention options are advancing, this advancement may not translate directly into reduced stigma, which is produced and reproduced by external barriers to accessing healthcare, and internalized by HIV positive people as emotional trauma. This research explores the relationship between the availability of contemporary resources for the treatment and prevention of HIV/AIDS, and the environment of stigma experienced by positive gay and bisexual men …

Psychotherapy Task-Based Assessment Of Therapists' Multicultural Orientation: A Measurement Development Study, Shaakira Haywood Stewart

Electronic Theses and Dissertations

Multicultural competencies (MCCs) have laid the foundation for therapists and researchers to strongly consider culture as an important factor in psychotherapy. More recently, Owen (2013) developed the multicultural orientation framework (MCO) to better explicate the MCCs for psychotherapy. The purpose of this dissertation was to develop a Multicultural Orientation Performance Task (MCO-PT) and coding system with therapists-in-training. For the MCO performance task, participants responded to eight brief simulated therapy situations that centered on the intersection of various cultural identities. Responses were recorded and coded for multicultural orientation. Prior to administration, vignettes were vetted by experts in the field. Approximately 100 …

Applied Machine Learning For Classification Of Musculoskeletal Inference Using Neural Networks And Component Analysis, Shaswat Sharma

Electronic Theses and Dissertations

Artificial Intelligence (AI) is acquiring more recognition than ever by researchers and machine learning practitioners. AI has found significance in many applications like biomedical research for cancer diagnosis using image analysis, pharmaceutical research, and, diagnosis and prognosis of diseases based on knowledge about patients' previous conditions. Due to the increased computational power of modern computers implementing AI, there has been an increase in the feasibility of performing more complex research.

Within the field of orthopedic biomechanics, this research considers complex time-series dataset of the "sit-to-stand" motion of 48 Total Hip Arthroplasty (THA) patients that was collected by the Human Dynamics …

Show Me A Sign: How Signs Embedded Within Social Media Shape And Influence Outdoor Recreational Tourists' Decision-Making Processes At Colorado State Parks, Sarah Marie Norlin

Electronic Theses and Dissertations

The purpose of this project was to determine the ways in which signs within social media posts on Instagram and Facebook frame the way that outdoor recreational tourists make decisions about Colorado state parks' locations, services and activities. Surveys were conducted at 6 Colorado state parks in the 2018 spring, summer, and fall months. These surveys asked respondents to answer multiple choice and open ended questions about their social media habits, their outdoor recreation habits, and their opinions about images displayed on Colorado Parks and Wildlife's social media pages.

A total of 93 surveys were collected during the research period. …

Changing The Rules Of The Game: Can Voicing For Social Responsibility Influence Market Behavior Toward Greater Inclusiveness In Economic Development?, Eileen M. Hoffmann

Electronic Theses and Dissertations

This thesis examines social responsibility within a capitalist economy by investigating socially responsible investing and, tangentially, corporate social responsibility. These concepts have been at the heart of economic and legal debates for hundreds of years, with no clearly defined consensus regarding how to account for multi-stakeholder welfare inside the market system. This point is brought to life by analyzing two dominant twentieth-century economic periods, 1945-1975/79 and post-1980, through the deliberations of Keynesian economics and Milton Friedman.

This thesis postulates that since the 2008 global financial crisis, a new (i.e. third) economic period is taking shape, ushered in by both the …

Using Repeat Photography To Examine Change In A U.S. National Park Gateway Community: A Case Study Of Estes Park, Colorado, Caitlin Lebeda

Electronic Theses and Dissertations

Since the creation of the National Park Service in the United States, tourists from around the world visiting America's national parks are served by gateway communities. Gateway communities are the towns and cities that border public lands and protected spaces. The impact of our visits on these gateway communities is considerable, with many gateways and their residents relying on consistent and ever-increasing visitation to national parks to spur economic growth and development. To better understand the impacts that national park designations have had on their gateway communities, it is important to determine what changes have occurred both physically and culturally …

New Insights Into Mycofactocin Biosynthesis, Structure And Function, Richard Selorm Ayikpoe

Electronic Theses and Dissertations

Mycofactocin is a putative ribosomally synthesized and post-translationally modified peptide (RiPP)-derived redox cofactor. Its biosynthesis is accomplished through the dedicated actions of the products of six conserved genes, mftABCDEF. The mycofactocin pathway is one of the most widely distributed RiPP systems in bacteria however, this distribution is heavily skewed towards the Mycobacteria genus including human pathogenic variants such as M. tuberculosis and M. ulcerans. Gene expression studies have demonstrated the essentiality of the pathway in the ability of M. tuberculosis to utilize the host's cholesterol as sole carbon source during latency. However, the biosynthesis, structure and physiological function …

The Movement Of The Spirit: A Constructive Comparison Of Divine Grace In The Theologies Of Paul Tillich And John Wesley, Thomas Albert Barlow Jr

Electronic Theses and Dissertations

This work is a constructive comparison of the ways in which the operations of divine grace resonate in the theologies of John Wesley and Paul Tillich. The primary questions which initially motivated this project: First, how does Tillich's concept of theonomy intersect Wesley's conceptions of the activity of grace? Second, how would those intersections serve to provide a renewed (or clarified) understanding of Wesley's framework of grace? How does Tillich's concept of theonomy, and his method of correlation, inform Wesley's understanding of the activity of grace in human culture? How might gleaned from this comparison inform the work of faith …