Digital Commons Network^™

Mesoporous Adsorbents For Perfluorinated Compounds, Bertha Lotsi

Electronic Theses and Dissertations

Effective adsorbents for polyfluorinated compounds (PFCs) were successfully prepared. And they were tested in the adsorption of perfluorooctanoic and perfluorooctanesulfonic acids. Bridged silsesquioxanes containing secondary and tertiary amino groups were synthesized by sol-gel condensation of bis[3-(trimethoxysilyl)propyl]amine and bis[3-(methylamino)propyl]-trimethoxysilane in acidic media with surfactants. Obtained materials are mesoporous with a high BET surface area. They combine high structural stability with a high concentration of surface amino groups serving as adsorption sites. Batch adsorption tests demonstrated their extremely high adsorption capacity on PFCs: in some experiments, it reached up to 88% of the adsorbent weight. Adsorption of PFCs changed the surfaces of …

Health Communication Via Social Media: How Pharmaceutical Companies Are Using Instagram For Corporate Social Responsibility, Abisoluwa Akinboboye

Electronic Theses and Dissertations

This study examines the depth of audience engagement with six dimensions of Corporate Social Responsibility (CSR) via the Instagram platforms of pharmaceutical companies. Recent research on the relationship between CSR and health communication has established a robust link between both variables but created a gap on the level of audience engagement. Drawing on Voluntary Disclosure, Agenda Setting and Media System Dependency theories, this study finds that voluntary communication of CSR strategies has the maximum potential to set the agenda for audience engagement on social media. The remodeled digitization of the media has increased the level of media dependency making social …

Managing Cosplay Performance: The Forms And Expectations Of Convention Roleplay, Isaac V. Price

Electronic Theses and Dissertations

Costume play (i.e. cosplay) is a performance of fandom rife with rituals and communication practices. Cosplay roleplaying performances are cultural practices that reveal how cosplayers interact with one another and among non-cosplaying members of their fandoms. This study examines the expectations that cosplayers hold for roleplay, the forms of roleplay, and the ways in which roleplay can become an instigator of harassment. Through the lens of Face-Negotiation Theory, the author discusses how roleplay functions to maintain or threaten the public images of cosplayers and their audiences, and what strategies cosplayers implement to avoid the loss of face.

An Unusual Mastodon Revisited: Providing A Regional Focus For Mammut Americanum (Proboscidea, Mammutidae) In The Southeast, Matthew Inabinett

Electronic Theses and Dissertations

A century ago, two large American mastodon Mammut americanum specimens from coastal South Carolina were mounted for display at Amherst College. Their robust build, broad and pentalophodont third molars, and well-developed mandibular tusks were noted as unusual. Here, these specimens are redescribed; three additional mastodon mandibles from the same region of South Carolina are also described. Though collection information on these specimens is sparse, they appear to span >150 ka in the Middle to Late Pleistocene, and probably include the first report of Mammut from the earliest-Rancholabrean Ten Mile Hill Formation. Some “unusual” features — moderately to extremely broad third …

Efficient Conditional Inactivation Of Rdh10 Reveals Important Role Of Retinoic Acid During Lung Branching Morphogenesis., Nhut Quang Huy Tran

Electronic Theses and Dissertations

Birth defects are complicated pathological processes. Many birth defects can be traced back to disrupted regulation of molecular signaling pathways during embryogenesis. One of the most important gene regulatory factors during embryo development is retinoic acid (RA). However, studying the specific roles of RA in each organ during embryogenesis in vivo is challenging. The Sandell laboratory has a conditional mutant mouse model that can potentially be used for studying the role of RA during embryogenesis by inducing stage-specific RA deficiency. This model allows retinol dehydrogenase 10 (Rdh10), a gene required for RA production, to be inactivated at a …

Alcohol Consumption In A Preclinical Model Of Schizophrenia, Liza Hernandez

Electronic Theses and Dissertations

Schizophrenia is a debilitating psychiatric disorder that affects approximately 1% of the global population. Schizophrenia is highly comorbid with other psychiatric disorders such as Alcohol Use Disorder (AUD) with a prevalence rate of 27% - 65%, which is significantly higher than AUD exhibited by the general population (6%). Research indicates that a higher rate of AUD in individuals suffering from schizophrenia may be related to the common neuronal pathways that underlie the expression of both disorders. The present study will determine whether the neonatal quinpirole (NQ) rodent model of schizophrenia will approximate the human condition and exhibit increased EtOH consumption. …

The Experiences And Well-Being Of Mexican Immigrant Women Living In Traditionally Non-Latinx Communities In Western North Carolina, Melinda Bogardus

Electronic Theses and Dissertations

North Carolina has, in recent decades, experienced significant growth in its Latinx, and more particularly Mexican immigrant population. As a traditionally non-Latinx state, or a state without a long-standing, large Latinx population, many communities and healthcare and service providers within North Carolina still lack knowledge, resources, and skills needed to serve and support Latinx immigrant populations well. Guided by interpretive description, this qualitative study on Mexican immigrant women in Western North Carolina sought to gain knowledge and understanding of what it is like for them to live in a traditionally non-Latinx region and how immigration has affected their well-being. Asking …

Chronoecology Of A Cave-Dwelling Orb-Weaver Spider, Meta Ovalis (Araneae: Tetragnathidae), Rebecca Steele

Electronic Theses and Dissertations

Circadian clocks enable coordination of essential biological and metabolic processes in relation to the 24-hour light cycle. However, there are many habitats that are not subject to this light cycle, such as the deep sea, arctic regions, and cave systems. This study analyzes the circadian pattern of isolated populations of a subterranean spider, Meta ovalis from two Tennessee caves and five Indiana caves. Locomotor activity was recorded with TriKinetics LAM50 Locomotor Activity Monitor under a 12-hour light (L), 12-hour dark (D) (LD 12:12) cycle preceding total darkness (DD). Significant differences were found within and among populations found in Tennessee cave …

Behavioral And Neurobiological Evidence Of Epigenetic Transmission In The Neonatal Quinpirole Rodent Model Of Schizophrenia, Wesley Gill

Electronic Theses and Dissertations

Quinpirole is a dopamine D2 receptor agonist that if administered to rats from postnatal day (P)1-21 results in increased dopamine D2 receptor sensitivity throughout the animal’s lifetime. This increase in receptor sensitivity is consistent with schizophrenia. This model has additional consistencies with human schizophrenia, including sensorimotor gating deficits, enhanced behavioral and neurobiological responses to nicotine, and protein alterations consistent with the disorder. In this study, a second generation of the neonatal quinpirole (NQ) rodent model was created to investigate if long term changes caused by NQ treatment would be passed to offspring. NQ treated rats were mated and their offspring …

Understanding The Implications Of Anandamide, An Endocannabinoid In An Early Land Plant, Physcomitrella Patens, Md Imdadul Haq

Electronic Theses and Dissertations

Endocannabinoid signaling is well studied in mammals and known to be involved in numerous pathological and physiological processes. Fatty acid amide hydrolase (FAAH) terminates endocannabinoid signaling in mammals. In Physcomitrella patens, we identified nine orthologs of FAAH (PpFAAH1 to PpFAAH9) with the characteristic catalytic triad and amidase signature sequence. Kinetics of PpFAAH1 showed specificity towards anandamide (AEA) at 37°C and pH 8.0. Further biophysical and bioinformatic analyses revealed that, structurally, PpFAAH1 to PpFAAH4 were closely associated to the plant FAAH whereas PpFAAH6 to PpFAAH9 were more closely associated to the animal FAAH. A substrate entry gate or ‘dynamic paddle’ …

Storm Sampling To Assess Inclement Weather Impacts On Water Quality In A Karst Watershed: Sinking Creek, Watauga Watershed, East Tennessee, Porcha Mccurdy

Electronic Theses and Dissertations

Escherichia coli changes in Sinking Creek, an impaired water body in the Watauga watershed of northeast Tennessee, were assessed during storm events using water samples collected with ISCO automated samplers during eight storms at two locations. Turbidity and electrical conductivity (EC) data loggers were deployed in the creek, and dissolved oxygen (DO) was measured in situ to test the stream’s water quality and reaction to inclement weather. Cotton fabric was deployed at both locations and sent to an external lab to test for the presence of Optical Brighteners (OB), which are indicators of residential wastewater. E. coli and turbidity at …

Association Of Perfluorinated Chemicals With Endocrino-Carcinogenetic, Obesogenic And Metabolic Health And With Markers Of Chronic Inflammation And Oxidative Stress, Ogbebor Enaholo Omoike

Electronic Theses and Dissertations

First, this study examined the association of perfluorinated chemicals with 1) cardio-metabolic health outcomes and 2) the association of phthalates with cardiometabolic health outcomes, and 3) cardio-metabolic health outcomes while assessing the possibility of additive interactions between perfluorinated chemicals (PFCs) and phthalates. Second, association with markers of chronic inflammation and oxidative stress were explored. Finally, this study examined the association of these chemicals with estrogenic cancers- Breast cancer, prostate cancer, uterine cancer and ovarian cancer.

Using data from the National Health and Nutrition Examination Survey (NHANES), logistic regression models were used to investigate the relationship between PFCs and the cardio-metabolic …

Govoreeting With Lewdies: A Critical Discourse Analysis Of A Clockwork Orange And Its Translations Across Media And Language, Willie Wallace

Electronic Theses and Dissertations

Much linguistic research has been done on the fictional argot of A Clockwork Orange, known as Nadsat, but few efforts have been made to expand beyond the classification and analysis of Nadsat. Using Critical Discourse Analysis, this paper looks at the overarching discourse of A Clockwork Orange and aims to answer three questions: What exigencies and discourses inform the creation of these works? What techniques and power structures are employed in the construction of these works? How do these works shape or attempt to shape the discourse? To answer these questions, I look at three instances of the discourse: …

Archaeological, Geophysical, And Geospatial Analysis At David Crockett Birthplace State Park, In Upper East Tennessee, Reagan Cornett

Electronic Theses and Dissertations

A geophysical survey was conducted at David Crockett Birthplace State Park (40GN205, 40GN12) using ground-penetrating radar (GPR) and magnetometry. The data indicated multiple levels of occupation that were investigated by Phase II and Phase III archaeological excavations. New cultural components were discovered, including the remnants of a Protohistoric Native American structure containing European glass trade beads and Middle Woodland artifacts that suggest trade with Hopewell groups from Ohio. A circular Archaic hearth was uncovered at one meter below surface and similar deep anomalies were seen in the GPR data at this level. A semi-automated object-based image analysis (OBIA) was implemented …

Ontogenetic And Adult Shape Variation In The Endocast Of Tapirus: Implications For T. Polkensis From The Gray Fossil Site, Thomas M. Gaetano

Electronic Theses and Dissertations

Endocranial morphology provides evidence of sensory ecology and sociality of extinct vertebrates. The Earliest Pliocene Gray Fossil Site (GFS) of NE Tennessee features a conspicuous dominance of skeletal elements belonging to the dwarf tapir, Tapirus polkensis. Numerous individuals in one fossil locality often suggests gregarious behavior, but sociality in T. polkensis contradicts behavior documented for extant Tapirus species. I test T. polkensis for variation in sensory and social ecology using computed tomography and 3D digital endocasts from an ontogenetic sequence. I compare the T. polkensis endocasts with extant Tapirus species using Encephalization Quotients (EQs) and 3D geometric morphometrics. Results …

Deconstructing The "Woman Of Sentiment": Parody As Agency In The Poetry Of Phoebe Cary, Scottie Garber-Roberts

Electronic Theses and Dissertations

The work of nineteenth-century American poet Phoebe Cary presents a complex puzzle of exigence and purpose that combines social structure, political climate, and personal history. Known for her somber and spiritual sentimental poetry, Cary shocked readers and reviewers alike when she published her collection Poems and Parodies in 1854, which contained a series of scathing and hilarious parodies based on popular sentimental poetry. In my thesis, I work to untangle the various contextual elements surrounding Cary’s writing in order to gain a better understanding of the dual nature of the poet and her work. Through an examination of nineteenth-century American …

Blend It Like Beckett: Samuel Beckett And Experimental Contemporary Creative Writing, Sam Nicole Campbell

Electronic Theses and Dissertations

Samuel Beckett penned novels, short stories, poetry, stage plays, radio plays, and scripts—and he did each in a way that blended genre, challenged the norms of creative writing, and surprised audiences around the globe. His experimental approach to creative writing included the use of absurdism, genre-hybridization, and ergodicism, which led to Beckett fundamentally changing the approach to creative writing. His aesthetics have trickled down through the years and can be seen in contemporary works, including Aimee Bender’s short story collection The Girl in the Flammable Skirt and Mark Z. Danielewski’s novel House of Leaves[1]. By examining these works …

The Emotional Plague, Nicholas Raynolds

Electronic Theses and Dissertations

The artist discusses his Master of Fine Arts thesis exhibition “the emotional plague” held at the Reese Museum in Johnson City, Tennessee from March 2nd through March 27th, 2020 in which he examines a number of literary and invented narrative subjects influenced by science fiction, Surrealism and the current political climate in an attempt to reconcile the social and the personal through the creative act.

Largely improvisational in their conception, the paintings and drawings in this exhibition reflect ideas derived from writers, thinkers and artists including Wilhelm Reich, J.G. Ballard, W.S. Burroughs and Goya, all distilled through the uncertain territory …

The Relationship Between Adverse Childhood Experiences, Acute Stress, And Working Memory, Marissa R. Jones

Electronic Theses and Dissertations

Working memory (WM) is a crucial component of cognitive function that affects learning, reasoning, and problem solving, all of which are important for daily functioning. Therefore, addressing factors that can impact working memory, such as stress, are incredibly relevant to understanding WM efficiency. WM is an important component of higher order cognitive function and high WM capacity has been shown to be important for academic and occupational performance. Thus, understanding the relationship between stress-related factors and WM could aid in identifying strategies to mitigate the deleterious effects of stress on working memory. Although some previous research has indicated a negative …

Protection Against Atherosclerosis By A Non-Native Pentameric Crp That Shares Its Ligand Recognition Functions With An Evolutionarily Distant Crp, Asmita Pathak

Electronic Theses and Dissertations

C-reactive protein (CRP) is an acute phase protein of the innate immune system that has been evolutionarily conserved. Human CRP is known to exist in two different pentameric conformations; native CRP and non-native CRP that possess differential ligand recognition functions. The structure of CRP evolved from arthropods to humans, in terms of subunit composition, disulfide bonds, and glycosylation pattern. Along with change in structure, the gene expression pattern of CRP also evolved from a constitutive protein in lower invertebrates to an acute phase protein in humans. The objective of this study was to determine the function of a non-native pentameric …

The Powerful Presence Of Dams In Appalachian Poetry, Zoe Hester

Electronic Theses and Dissertations

Contemporary Appalachian poetry offers a lens through which we can see the immense impact that the Tennessee Valley Authority has had in Appalachia. In this thesis, I explore the powerful presence of dams in Appalachian poetry by analyzing three poems. Jesse Graves’s “The Road into the Lake” centers on personal and familial loss, Jackson Wheeler’s “The TVA Built a Dam” mourns the loss of communities, and Rose McLarney’s “Imminent Domain” focuses on the ecological destruction that has occurred in Appalachia and around the globe as the result of the construction of TVA dams. Ultimately, all three poems serve as eulogies …

Managing Stress In A Constantly-Changing Workforce, Lorri Burch-Hubbard

Electronic Theses and Dissertations

When staffing reductions occur in the workplace, staff left behind may face increased stress, may not be given the support they need to manage the feelings caused by the reduction. This study was conducted to evaluate the impact of stress caused by staffing reductions has on medical technologists (MT), medical technicians (MLT) and respiratory therapists (RT), and to identify any common methods of stress management used by those staff who remain in the organization.

Literature research showed the negative impact stress can have on individuals when it is not addressed, such as decreased work performance, health issues, and even the …

Health And Academic Achievement In College And University Students, Amber Beane

Electronic Theses and Dissertations

The purpose of this non-experimental quantitative correlational study was to investigate the relationship between academic achievement and health in a national sample of college students using quantitative data analysis. Specifically, the researcher analyzed the relationship between three health-promoting behaviors (physical activity, strength training, and fruit and vegetable consumption), three negative health behaviors (cigarette, e-cigarette, and opioid use) and obesity with GPA.

Cross-sectional data on student health collected from the American College Health Association’s National College Health Assessment II (ACHA-NCHA-II) and completed by 426,650 college students from 650 U.S. colleges during the semesters between 2015 and 2019 formed the foundation for …

Encephalization In Commensal Raccoons: A Unique Test Of The Cognitive Buffer Hypothesis, Peter M. Anderson

Electronic Theses and Dissertations

This study investigated selective pressures associated with encephalization in mammals and discussed broader implications. Relative brain size as measured by EQ (Encephalization Quotient) was compared between ecological categories. Omnivores had higher average EQ than ecological specialists. Since specialists are disproportionately affected by extinction events, selection for ecological generalism is proposed as encephalization mechanism. This mechanism may reinforce the more widely known Cognitive Buffer Hypothesis (CBH)—the idea that possessing relatively large brains has buffered lineages against environmental change. CBH is tested here by comparing EQs in Procyon lotor (raccoon) in urban and rural environments. CBH predicts that raccoons in the most …

Rural-Urban Variations In Meals On Wheels Programs, Lea C. Florence

Electronic Theses and Dissertations

Older adults are living longer than ever before. By 2060, the U.S. population aged 65 or older is projected to reach 98 million. As adults age, the prevalence of chronic diseases and disabilities increases. The need for Meals on Wheels (MOW) services is growing alongside the aging population. Yet, little is known about the geographic variation of services. Little is documented about the organizational capacity of MOW organizations in terms of geography. The current policies supporting home-and community-based services, including MOW, may be insufficient to support all older adults in all types of communities. An analysis of the More Than …

Behind The Screens: Understanding The Social Structures Of The Video Game Industry, Michelle Lalonde

Electronic Theses and Dissertations

This study focuses on video game developers and their working environments in a growth industry. While some research documents the culture of video games and the people who play them, much less is understood about the labor environment for those who make games. I conducted 20 personal interviews with game developers in order to learn more about what inspired them to select this field, how they gained entry to it, and what their work is like today. Using insights from the interviews, I analyze how workers contend with its male-dominated culture and how creative skilled laborers deal with the challenges …

A Tale Of Two Species: Black-Tailed And White-Tailed Prairie Dog Biogeography From The Last Interglacial To 2070, April Dawn Bledsoe

Electronic Theses and Dissertations

Ecological niche models (ENMs) were created for White-tailed and Black-tailed prairie dogs and projected into the Last Interglacial (LI), the Last Glacial Maximum (LGM), and mid-Holocene (mid-H) to discern possible past suitable habitat for both species. Additionally, ENMs were projected into the future year 2070 representative concentration pathways (RCPs) 2.6 and 8.5 to discern how climate change may affect future habitat suitability. Kernel density estimations, minimum convex polygons, and median distribution centers of White-tailed and Black-tailed occurrence records were examined between time-periods to discern the effects of anthropogenic westward expansion on both species’ distributions. Current ENMs were constructed from commonly …

Ritualistic Equestrianism: Status, Identity, And Symbolism In Tudor Coronation Ceremonies, Keri Blair

Electronic Theses and Dissertations

The crowning of a King or Queen of England is and remains an essential part of English tradition. For centuries, British subjects have flocked to the city streets to catch a glimpse of their next monarch. For the Tudors, the spectacle of pageantry was often an ostentatious display of wealth and grandeur. Using horses as an historical lens, this study will examine four different components of equestrianism in Tudor coronation ceremonies: The King’s Champion, the Gilded Spurs, the Master of the Horse, and the Horse of Honor. Despite significant political, religious, and cultural changes that occurred during the Tudor era, …

A Novel Mode Of Action Of C-Reactive Protein In Protecting Against Streptococcus Pneumoniae Infection And Synergy With Antibiotics, Donald Ngwa

Electronic Theses and Dissertations

C-reactive protein (CRP) is a part of the innate immune system, is synthesized in the liver, its blood level increases in inflammatory states, and it binds to Streptococcus pneumoniae. The conformation of CRP is altered under conditions mimicking an inflammatory milieu and this non-native CRP also binds to immobilized/aggregated/pathogenic proteins. Experiments in mice have revealed that one of the functions of CRP is to protect against pneumococcal infection. For protection, CRP must be injected into mice within two hours of administering pneumococci, thus, CRP is protective against early-stage infection but not against late-stage infection. It is unknown how CRP protects …

Chasing Destiny: A Novella, Kassandra Kim

Electronic Theses and Dissertations

Chasing Destiny tells the story of Lyric Angel de la Cruz. She is the only daughter of five-time world heavyweight champion and three-time tag team champion Manuel de la Cruz and the oldest granddaughter of Julio de la Cruz, a legend in the wrestling world. For as long as Lyric can remember, her life has been surrounded by wrestling, and she wants to be involved with the business. But unlike her family that came before her. Lyric wants to create her own way in the business, however, when she tells Manuel her career path, he is furious that she would …