Digital Commons Network^™

Forecasting Vibrio Parahaemolyticus In A Changing Climate, Meghan Ann Hartwick

Doctoral Dissertations

The distribution, transmission and adaptation patterns of infectious diseases are changing worldwide. Though there are many potential mechanisms that can transmit infectious agents to new areas, the ability of pathogens to persist in new locations can be largely attributed to changing climate conditions, especially in temperate regions. Vibrio parahaemolyticus, a naturally occurring bacteria in most marine and estuarine systems, provides a model example of these globally observed climate-related changes to disease dynamics that are occurring locally in the Northeast, US. Like many Vibrio species, pathogenicity in human hosts is believed to be limited to a subset of strains, whereas the …

The Role Of Replication Protein A Large Subunit Family In Pathogen-Induced Dna Damage In Arabidopsis Thaliana, Nancy Lynn Fernandes

Doctoral Dissertations

The DNA of every organism is under continuous attack from both environmental agents, errors in DNA replication, and reactive oxygen species produced from cellular metabolism. The preservation of genome stability and integrity is essential to counteract threats to genome integrity. Eukaryotic organisms have evolved a complex set of mechanisms to sense DNA damage and initiate repair of the damage or death of the cell, collectively called the DNA damage response (DDR).

One of the main causes of detrimental DNA damage is due to microbial pathogens, both in mammals and in plants. In humans Escherichia coli, Helicobacter pylori and Pseudomonas aeruginosa …

Fatigue Assessment Of Complex Structural Components Of Steel Bridges Integrating Finite Element Models And Field-Collected Data, Maryam Mashayekhizadeh

Doctoral Dissertations

Fatigue damage in welded structural steel components has a complex presentation, which is influenced by the geometric configuration of the component and load path in a structural system. The classic fatigue assessment methods, using nominal stresses and S-N curves, may not capture nor predict the complicated performance of the component with respect to fatigue. Recent novel complex steel structural connections that experience multi-axial behavior or do not fit any conventional fatigue categories are not explicitly addressed in the existing fatigue design codes. An ideal fatigue estimation for the complex structural components is dependent on a thorough understanding of structural performance …

Effects Of Waves, Tides, And Vegetation On The Distribution Of Bed Shear Stress In The Great Bay Estuary, Nh, Salme Cook

Doctoral Dissertations

The goals of this research are to expand our understanding of, and improve predictions of bed shear stress in estuarine environments using both observational datasets and numerical modeling. To accurately predict sediment transport, a good understanding of the bed shear stress that drives the sediment erosion, suspension and deposition is essential. Shear stress is a function of both the hydrodynamics in the system and the characteristics of the sediment that comprise the bed itself. The hydrodynamic forcing is determined by tides, waves, meteorological effects, rivers, or some combination that can change on time scales of a few minutes to a …

Assessing Potential Impacts Of Climate Change On American Lobsters (Homarus Americanus) With Novel Tools And Techniques, Benjamin C. Gutzler

Doctoral Dissertations

The Gulf of Maine is currently experiencing rapid environmental changes, in the form of warming temperatures, increasing acidity, and a benthic ecosystem that is dominated by the American lobster (Homarus americanus) as the sole major predator and most significant fishery. The overall goal of my dissertation research was to investigate how the increased stress from warmer, more acidic, waters might impact individual lobsters, and thus lobster populations. To address this overall objective it was necessary to develop novel methods for investigating lobster behavior and reproduction, a theme that will run throughout this dissertation. In Chapter Two, I developed a new …

Estimation Of Measurement Uncertainty Of Seafloor Acoustic Backscatter, Mashkoor Malik

Doctoral Dissertations

In the last three decades, Multibeam echo sounders (MBES) have become the tool of choice to study the seafloor. MBES collects two distinct types of data: bathymetry that provides topographic details of the seafloor and backscatter that has the potential to characterize the seafloor. While the uncertainty associated with MBE bathymetry has been well studied, the uncertainty in MBES backscatter measurement has received relatively little attention, hindering the improvements in quantitative analysis of backscatter data. Both acquisition and processing stages can introduce uncertainty in the final seafloor backscatter products. Application of well-established uncertainty quantification principles to seafloor backscatter data is …

Acoustic Methods For Mapping And Characterizing Submerged Aquatic Vegetation Using A Multibeam Echosounder, Ashley Rose Norton

Doctoral Dissertations

Submerged aquatic vegetation (SAV) is an important component of many temperate global coastal ecosystems. SAV monitoring programs using optical remote sensing are limited by water clarity and attenuation with depth. Here underwater acoustics is used to analyze the water volume above the bottom to detect, map and characterize SAV. In particular, this dissertation developed and applied new methods for analyzing the full time series of acoustic intensity data (e.g., water column data) collected by a multibeam echosounder. This dissertation is composed of three separate but related studies. In the first study, novel methods for detecting and measuring the canopy height …

Synthesis And Applications Of Ceramic (Silicon Carbide And Silicon Nitride), Metallic (Cobalt(0)) And Polymeric (Polyurethane) Aerogels, Parwani M. Rewatkar

Doctoral Dissertations

"A new method has been demonstrated for the synthesis of monolithic ceramic and purely metallic aerogels from xerogel powder compacts, and the use of polyurethane aerogels based on cyclodextrins as efficient desiccants.

I. Highly porous ( > 80%) monolithic SiC and Si₃N₄, aerogels were prepared from compressed compacts of polyurea-crosslinked silica xerogel powders. The process is time efficient as solvent-exchange through powders is fast, and energy efficient as it bypasses drying with supercritical fluids. The final ceramic objects were chemically pure, sturdy, with compressive moduli at 37 ±7 MPa and 59 ± 7 MPa, and thermal conductivities …

Mass Spectrometry Analysis Of Contaminants Of Emerging Concern: Nanoparticles, Algal Toxins, And Cyanotoxins In Natural Waters And Their Potential Health Impacts, Ariel R. Donovan

Doctoral Dissertations

“The analysis of contaminants of emerging concern is critical to protecting environmental health. In the presented dissertation, two groups of contaminants of emerging concern were assessed using mass spectrometry methods: nanoparticles and algal and cyanotoxins.

Analysis of metal oxide nanoparticles in environmental matrices has been a challenging issue, as most traditional methods require complicated sample preparation methods or that can alter or destroy the nanoparticles in the system. Single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) methods were used to detect metal oxide nanoparticles in surface waters and their removal through drinking water treatment simulations while retaining all information regarding …

New Reproducing Kernel Hilbert Spaces On Plane Regions, Their Properties, And Applications To Partial Differential Equations, Jabar S. Hassan

Doctoral Dissertations

"We introduce new reproducing kernel Hilbert spaces W₂^(m,n) (D) on unbounded plane regions D. We study linear non-homogeneous hyperbolic partial differential equation problems on D with solutions in various reproducing kernel Hilbert spaces. We establish existence and uniqueness results for such solutions under appropriate hypotheses on the driver. Stability of solutions with respect to the driver is analyzed and local uniform approximation results are obtained which depend on the density of nodes. The local uniform approximation results required a careful determination of the reproducing kernel Hilbert spaces on which the elementary …

The Effects Of Low Aspect Ratio And Heat Exchanging Internals On The Bubble Properties And Flow Regime In A Pilot-Plant Bubble/Slurry Bubble Column For Fischer-Tropsch Synthesis, Hayder Al-Naseri

Doctoral Dissertations

"Fischer-Tropsch synthesis (F-T) is a process utilized to convert the syngas mixture of CO and H₂ to synthetic fuel and chemicals that executed commercially by using the bubble/slurry bubble column reactor. The experimental results reveal that the investigated parameters, in terms the presence of internals, and reducing the aspect ratio and the solids loading, increase the local gas holdup, interfacial area, bubble passage frequency, and decrease the bubble rise velocity, bubble chord length. Meanwhile, the aspect ratio H/D = 4, and 5 provide enough height to established the fully developed flow regime. As a result of the variation in …

Ferrite Characterization Techniques & Particle Simulations For Semiconductor Devices, Nicholas Erickson

Doctoral Dissertations

"This dissertation is divided into three papers, covering two major topics. The first topic, techniques for ferrite characterization, is discussed over the course of two papers. The second topic, particle simulations for semiconductor devices, is discussed in the last paper. In the first paper, the method for extracting permeability from ferrite materials is discussed for the Keysight 16454A permeability extraction fixture, where the ferrite material to be characterized is assumed to be homogeneous. Then the method is updated to account for layered materials. The updated method is verified through full-wave simulations. In the second paper, a planar printed circuit board …

Microstructural Evolution Of Zirconium Carbide (Zrcₓ) Ceramics Under Irradiation Conditions, Raul Florez

Doctoral Dissertations

A comprehensive understanding of the microstructural evolution of Zirconium Carbide (ZrC₂) ceramics under irradiation conditions is required for their successful implementation in advanced Gen-IV gas-cooled nuclear reactors. The research presented in this dissertation focusses on elucidating the ion and electron irradiation response of ZrC₂ ceramics. In the first part of the research, the microstructural evolution was characterized for ZrC₂ ceramics irradiated with 10 MeV Au³⁺ ions up to doses of 30 displacement per atom (dpa) at 800 ºC. Coarsening of the defective microstructure, as a function of dose, was revealed by transmission electron microscopy analysis. …

Design And Prototyping Of A Real-Time Millimeter Wave Imaging System, Zahra Manzoor

Doctoral Dissertations

"The goal of this work is to design, prototype and test an innovative millimeter wave imaging system that operates in the frequency range of 33-35 GHz and is capable of producing rapid images of various diverse scenes. In particular, the imaging system includes two main sections, one is related to the hardware design of the system, and the other focuses on the development of a novel comprehensive image reconstruction algorithm. The hardware design includes custom transmitter and receiver sub-systems, and a sparse switched array which was optimized for 320 mm x 220 mm aperture plane, and also included an improved …

Smart Control Architecture For Microgrid Application, Vikram Roy Chowdhury

Doctoral Dissertations

"This research proposes non-linear control architectures dedicated towards improving transient response, reliability and computational burden for grid connected inverters applicable for ac micro-grids. Also this work proposes an optimization procedure applied to a small microgrid to reduce the billing cost for power incorporating battery degradation mechanism.

Three works are discussed in this research that discusses methodologies to improve the operation of a three phase grid connected inverters. The first work discusses a globally stable estimation architecture for estimating the plant parameters for a grid connected inverter during its operation. Then a Lyapunov based control architecture is utilized and online parameter …

Biomaterials For Bone Regeneration, Youqu Shen

Doctoral Dissertations

"The purpose of this Ph.D. research is to investigate and improve two classes of hydroxyapatite (HA)-based biomaterials for bone repair: calcium phosphate microspheres and bioactive silicate glass scaffolds. These biomaterials were prepared with modified compositions and microstructures and then were evaluated for bone regeneration.

The open HA microspheres with dense convex surfaces and rough and porous concave surfaces were obtained by sectioning closed hollow HA microspheres. Bone regeneration with the open HA microspheres was greater than with the closed HA microsphere at 12 weeks. Hollow biphasic calcium phosphate (BCP) microspheres have been prepared with different fractions of HA and β-TCP …

Improvements In Digital Image Correlation And Application In Material Mechanical Test, Yunlu Zhang

Doctoral Dissertations

"Digital image correlation (DIC) is a non-contact full-field optical measurement method. With the advantages of high accuracy, low cost, and simple implementation, it has been widely applied in the area of experimental mechanics. In this study, DIC algorithm has been improved in the aspects of the pixel-level searching method and reference frame update strategy. The feature matching based method is proposed to provide an initial guess for all points of interest with semi-subpixel level accuracy in cases with small or large translation, deformation, or rotation. The bisection searching strategy is presented to automatically adjust the frame step for varying practical …

Long Period Fiber Grating, Thin Coating Of Graphene And Silver Nanowires, And Corrosion Sensing For Life-Cycle Assessment Of Steel Structures, Chuanrui Guo

Doctoral Dissertations

"This study aims to develop and validate a compact, integrated lab-on-sensor system for simultaneous measurement of strain, temperature and corrosion-induced mass loss in steel structures and concrete reinforcement elements in order to assess their life-cycle performance. The sensing system operates based on the principle of long period fiber gratings (LPFG) that are responsive to both thermal and mechanical deformation, and the change in refractive index of any medium surrounding the optical fiber. To fabricate a LPFG sensor for strain and temperature measurement, a CO₂ laser aided fiber grating system was assembled. To enable mass loss measurement, a low pressure …

Wavelength-Selective Metamaterial Absorber And Emitter, Zhigang Li

Doctoral Dissertations

"Electromagnetic absorbers and emitters have been attracting interest in lots of fields, which are significantly revitalized because of the novel properties brought by the development of the metamaterials, the artificially designed materials. Metamaterials broadens the approaches to design the electromagnetic absorbers and emitters, making it possible to obtain the perfect absorption or emission at the wavelengths covering a wide range. Metamaterial absorbers and emitters are promising for various applications, including solar thermal-photovoltaics and thermal-photovoltaics for energy harvesting, chemical and biomedical sensors, nanoscale imaging and color printing. This work focuses on three aspects (materials, structures and design methods) to improve the …

Seismic Attribute Assisted Depositional Facies Identification And Stratigraphic Correlation In The Central Gulf Coast Region Of Texas, Yani Lin

Doctoral Dissertations

"The sandstone deposits in the fluvial-dominated delta systems in the Lower Wilcox Group above the Cretaceous carbonate shelf edges of the Texas Gulf Coast Region are considered as high exploration potential reservoir bodies. However, the multi-phase regression and transgression during the late Paleocene to the early Eocene complicate the local depositional structure. The depositional facies is hard to be identified in details using the traditional seismic stratigraphic interpretation method. Seismic attributes are effective in detecting depositional facies, especially in mapping channels and investigating reservoir characteristics. In this study, we utilize seismic attributes to identify the principal depositional facies in the …

Transformational And Transactional Leadership Outcomes On The City Of Oakland By Demographics, Jason W. Mitchell

Doctoral Dissertations

This study utilized a quantitative method, using surveys of workers in the public sector in the City of Oakland to determine the barriers that make it difficult to manage performance and tackle complex issues of that organization. Further, this study delved into the possibility for these leaders to create transactional or transformational environments in this sector. The goal was to find issues that make it difficult for public-sector executives to lead effectively; that is, the goal was to discern factors that prohibit executives from delivering high-quality and efficient services to the public and developing change management. This survey is vital …

Predictive Analysis Of Real-Time Strategy Games Using Graph Mining, Isam Abdulmunem Alobaidi

Doctoral Dissertations

"Machine learning and computational intelligence have facilitated the development of recommendation systems for a broad range of domains. Such recommendations are based on contextual information that is explicitly provided or pervasively collected. Recommendation systems often improve decision-making or increase the efficacy of a task. Real-Time Strategy (RTS) video games are not only a popular entertainment medium, they also are an abstraction of many real-world applications where the aim is to increase your resources and decrease those of your opponent. Using predictive analytics, which examines past examples of success and failure, we can learn how to predict positive outcomes for such …

Study Of Optical Propulsion Concepts And Techniques For Small-Satellites, Jaykob Neil Maser

Doctoral Dissertations

"The first objective of this research is to manufacture and investigate the characteristics and use of asymmetric, metallic, nanostructures for plasmonic force propulsion, a developing method of nano-/picosatellite thrust generation. This project developed a higher-fidelity model of a recently envisioned small spacecraft propulsion system for precision pointing and proximity control. Plasmonic force propulsion harnesses solar light focused onto plasmon reactive sub-wavelength nanostructures to generate polarized oscillations of electrons on the surface of metallic nanostructures which accelerate and expel nanoparticle propellant via strong optical forces. This research also explores how material selection affects the electromagnetic response of the closely positioned asymmetric …

Design, Synthesis, Characterization And Anti-Cancer Effects Evaluation Of Interchain Cysteine Linked Antibody Drug Conjugates, Ke Li

Doctoral Dissertations

"Antibody drug conjugates (ADCs) are emerging therapeutic products specially designed for the treatment of cancers. Potent cytotoxic agents are linked to antibodies via linkers. Antibody drug conjugates, which take advantage of both antibodies and cytotoxic agents, showed high selectivity towards cancer cells. Cytotoxic agents are delivered to the cancer cells selectively and kill them from inside while leaving low or non-toxicity towards normal cells. Antibody drug conjugates are actually heterogeneous mixtures. The major heterogeneities mainly lie in the drug to antibody ratio (DAR) and drug linking positions, both of which potentially affect the therapeutic index of ADCs. In this research, …

Improving Base Metal Electrowinning, Charles Ebenezer Abbey

Doctoral Dissertations

"In zinc electrowinning, Mn oxidizes to form MnO₂ on Pb-Ag anodes, cell walls and pipes. MnO₂ reduces anode corrosion but also leads to short circuits and maintenance issues. MnO₂ is thought to interact with chloride ions and produce oxidized chlorine species. The interactions between Mn and Cl are not well understood. Bench scale experiments were conducted to investigate the effects of the manganese to chloride ratio on anode corrosion rate and electrolyte chemistry using rolled Pb-Ag anodes. Increasing the average Mn/Cl^- ratio from ~7:1 to ~11:1 reduced the anode corrosion rate. Anode scales produced with Mn/Cl …

Hardware Architectures For Compact Microwave And Millimeter Wave Cameras, Matthew Jared Horst

Doctoral Dissertations

"Millimeter wave SAR imaging has shown promise as an inspection tool for human skin for characterizing burns and skin cancers. However, the current state-of-the-art in microwave camera technology is not yet suited for developing a millimeter wave camera for human skin inspection. Consequently, the objective of this dissertation has been to build the necessary foundation of research to achieve such a millimeter wave camera. First, frequency uncertainty in signals generated by a practical microwave source, which is prone to drift in output frequency, was studied to determine its effect on SAR-generated images. A direct relationship was found between the level …

The Tabu Ant Colony Optimizer And Its Application In An Energy Market, David Donald Haynes

Doctoral Dissertations

"A new ant colony optimizer, the 'tabu ant colony optimizer' (TabuACO) is introduced, tested, and applied to a contemporary problem. The TabuACO uses both attractive and repulsive pheromones to speed convergence to a solution. The dual pheromone TabuACO is benchmarked against several other solvers using the traveling salesman problem (TSP), the quadratic assignment problem (QAP), and the Steiner tree problem. In tree-shaped puzzles, the dual pheromone TabuACO was able to demonstrate a significant improvement in performance over a conventional ACO. As the amount of connectedness in the network increased, the dual pheromone TabuACO offered less improvement in performance over the …

Reliability Analysis For Systems With Outsourced Components, Zhengwei Hu

Doctoral Dissertations

"The current business model for many industrial firms is to function as system integrators, depending on numerous outsourced components from outside component suppliers. This practice has resulted in tremendous cost savings; it makes system reliability analysis, however, more challenging due to the limited component information available to system designers. The component information is often proprietary to component suppliers. Motivated by the need of system reliability prediction with outsourced components, this work aims to explore feasible ways to accurately predict the system reliability during the system design stage. Four methods are proposed. The first method reconstructs component reliability functions using limited …

Plugging Performance Of Preformed Particle Gels In Fractures And Its Influencing Factors, Ze Wang

Doctoral Dissertations

"Preformed particle gels (PPG) has been successfully applied to combat the water channeling caused by fractures or fracture-like channels. Understanding the placement and plugging of PPG in fractures is crucial for gel treatment design. The objective of the dissertation is to explore the plugging performance of three PPG products in two types of fracture models, the partially and fully open fractures. The following studies has been conducted and conclusions have been drawn based on the results and analysis. First, the placement and plugging performance of conventional PPG was investigated using core flooding experiments conducted partially open fractures. The plugging efficiency …

Military Applications Of Geological Engineering, Stephen H. Tupper

Doctoral Dissertations

"This work examines the premise that military engineering and geological engineering are intellectually paired and overlapped in practice to a significant extent. Geological engineering is an established, albeit young, academic discipline that enjoys wide industry and civil demand and is supported by many professional organizations. In contrast, military engineering is an ancient, empirically derived training or "OJT" program with practice-based trade-associations that has narrow government-only utility. The premise is formed by decades-long observation of U. S. Army military engineer officers completing a Master of Science degree in geological engineering as a complement to their practice-based training in military engineering at …