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Direct Recruitment Of Eif4gi And/Dap5 To The 5' Utr Of A Subset Of Human Mrna Drives Their Cap-Independent Translation, Solomon A. Haizel
Direct Recruitment Of Eif4gi And/Dap5 To The 5' Utr Of A Subset Of Human Mrna Drives Their Cap-Independent Translation, Solomon A. Haizel
Dissertations, Theses, and Capstone Projects
During unfavorable cellular conditions (e.g., tumor hypoxia, viral infection, nutrient deprivation, etc.), the canonical, cap-dependent translation initiation pathway in human cells is suppressed by sequestration of the cap-binding protein, eukaryotic initiation factor(eIF) 4E, by 4E-binding proteins. Circumvention of cap-dependent translation shutdown has been linked to tumor development and cancer progression. The stress-induced repression of cap-dependent translation has also been correlated with increased eIF4GI and its homolog, Death Associated Protein 5 (DAP5) expression levels, suggesting these factors have a role in cap-independent translation. Despite several evidence pointing towards a link upregulation of eIF4GI and /DAP5 levels during stress conditions, and the …
The Seduction Of Pessimism: Eros, Failure, And The Novel, Tom Ribitzky
The Seduction Of Pessimism: Eros, Failure, And The Novel, Tom Ribitzky
Dissertations, Theses, and Capstone Projects
In Plato’s Symposium, we get a pessimistic myth not only about love, but about the first experience of loss, in which we were once globular cosmic beings who were split in two by Zeus’s thunderbolts as punishment for not obeying the Olympian gods. Falling down to earth after the split, Zeus introduced eros out of pity for our condition. Our consolation was to find our other halves and hold on to them as a way of remembering what it was like when we were whole. But, as Allan Bloom notes:
…man’s condition soon worsened. In the beginning, their real …
The Hamite Must Die! The Legacy Of Colonial Ideology In Rwanda, Awa Princess E. Zadi
The Hamite Must Die! The Legacy Of Colonial Ideology In Rwanda, Awa Princess E. Zadi
Dissertations, Theses, and Capstone Projects
April 07, 1994, will forever remain in the history of Rwanda, as it commemorates the beginning of the Rwandan genocide. In 100 days, an estimated 800,000 people, who were overwhelmingly Tutsi, lost their lives at the hand of their neighbors, friends, and families. Although the genocide occurred 26 years ago, there is still much debate surrounding the cause of this tragedy. While some scholars have suggested that the genocide was triggered by contemporary economic and political factors, this thesis is taking a post-colonial approach by bringing into context the colonial history of Rwanda. In the discussion of these colonial roots, …
The One-Armed Viewer: Voyeurism And Masturbation In Nudist Imagery And Film Spectatorship, Benjamin Eleanor Adam
The One-Armed Viewer: Voyeurism And Masturbation In Nudist Imagery And Film Spectatorship, Benjamin Eleanor Adam
Dissertations, Theses, and Capstone Projects
Nudist magazines and newsletters were among the first commercial, legal, and widely-available images of nudity which circulated in the late Comstock Era. To evade censorship, producers developed framing strategies that obscured the sexualized nature of these images, even as they also enabled the viewing practices their sales relied upon. This dissertation traces these framing strategies as they evolved through nudist still-imagery, camp films, and nudie cuties, and considers the evolution of spectatorial pleasures associated with Russ Meyer's early nudie cuties.
Video On Film: Video Essay, Videographic Criticism, And Digital Academic Publishing, Tian Leng
Video On Film: Video Essay, Videographic Criticism, And Digital Academic Publishing, Tian Leng
Dissertations, Theses, and Capstone Projects
In the 2010s, an academic practice called “videographic criticism,” utilizing video essay creation and digital academic publishing, became a popular form of film criticism in the field of film studies. The emergence of such a videographic trend in academia and the existence of video essays in public video-sharing websites have made the task of justifying the scholarly values of video essays an urgent one. Through the analysis of the relationship between the video essay and the essay film, this study shows that the essayistic mode is crucial to distinguish videographic criticism from popular commentary. To understand the potentials of videographic …
Own Your Politics: The Entanglement Of Resistance And The Luxury Fashion Industry, Brent A. Van Horne
Own Your Politics: The Entanglement Of Resistance And The Luxury Fashion Industry, Brent A. Van Horne
Dissertations, Theses, and Capstone Projects
This thesis takes as its subject the increasing instrumentalization of social and political content by the fashion industry in recent years. Such content raises questions about the relationship between notions of political resistance and market capitalism. Marxist theorists such as Frederic Jameson and David Harvey would perhaps view this phenomenon as a confirmation of the ways in which late capitalism incapacitates forms of political descent by absorbing it within its machinations. Within this line of thinking, the way in which various designers use the fashion runway as a forum for protest would suggest late capitalism’s seemingly boundless ability to absorb …
Serial Killer: Gustave Flaubert's Pro-Woman, Woman-Killing Madame Bovary, Francesca Montalti
Serial Killer: Gustave Flaubert's Pro-Woman, Woman-Killing Madame Bovary, Francesca Montalti
Dissertations, Theses, and Capstone Projects
This thesis will argue that Gustave Flaubert kills the women in Madame Bovary, all of whom are married and/ or mothers in the novel, in order to overtly represent the impossible conditions of womanhood and domestic life in nineteenth century France. Further, I will expose the ways in which Flaubert, through these killings, aims to release his woman characters from their lives of oppression and imprisonment, detailing their increasingly limited options in life and their lack of agency. Although Flaubert does attempt to give his women, in particular Emma Bovary, limited agency in the work, this agency is always …
Caffeine Modulation Of Attention And Focus In Task Performance, Claudia R. Berger
Caffeine Modulation Of Attention And Focus In Task Performance, Claudia R. Berger
Dissertations, Theses, and Capstone Projects
Caffeine has been a heavily researched drug for decades given its prevalence in global consumption, as well as its large impacts on metabolic and executive function research alike. The present study aims to combine a behavioral study (Experiment 1) with a feasibility study (Experiment 2) to test the impacts of variable caffeine consumption on task performance. For both studies, participants filled out a questionnaire regarding caffeine use. Experiment 1 examined whether caffeine modulated attention in an online behavioral task in which participants were asked to identify a target (e.g., female “ahpa”). Participants were tested twice once after consuming 12 ounces …
Reimagining Post-Secondary Training, Community College, And Welfare Supports, Aaron Azerad
Reimagining Post-Secondary Training, Community College, And Welfare Supports, Aaron Azerad
Dissertations, Theses, and Capstone Projects
This paper seeks to study the income patterns at the sub-bachelorette level through community colleges and workforce training programs. Using 2018 U.S. Census PUMA microdata, this thesis not only explores which fields of study, industries, and occupations have a sufficient number of observations to determine whether they provide incomes which are commensurate with a middle class livelihood but, also whether these jobs are plentiful in number.
The second goal is to evaluate the effects of the 1996 Personal Responsibility and Work Opportunity Reconciliation Act (the Clinton era welfare reform) and how it has influenced Giuliani era ‘work requirement’ initiatives tied …
Role Of Protonation State Changes And Hydrogen Bonding Around The Oxygen Evolving Complex Of Photosystem Ii, Divya Matta
Role Of Protonation State Changes And Hydrogen Bonding Around The Oxygen Evolving Complex Of Photosystem Ii, Divya Matta
Dissertations, Theses, and Capstone Projects
The mechanism of natural photosynthesis involves the use of solar energy to produce O2 we breathe and food and fuel we intake. This process results in the biological oxidation of water that takes place at room temperature, neutral pH using earth abundant elements Ca and Mn. Understanding how this challenging chemical reaction occurs in photosynthesis can be useful for designing better artificial photosynthetic complexes that can be used as biofuels. My doctoral work is to study the deprotonation and oxidation events elucidating the mechanistic details of proton coupled electron transfer reaction in a photosynthetic protein.
The O2 evolution …
Introducing Odysseus: Force, Resistance And Nostos In The Formation Of Odysseus’ Character, Haley Ryan
Introducing Odysseus: Force, Resistance And Nostos In The Formation Of Odysseus’ Character, Haley Ryan
Dissertations, Theses, and Capstone Projects
This thesis explores the ways in which Odysseus’ self-introductions to other characters in the Odyssey reveal the complexities of his character with regard to homecoming and his apparent resistance to it. In examining these introductions, the thesis argues that Odysseus that the language Odysseus uses when he introduces himself is often filled with allusions to force and resistance, indicating that he is perhaps more ambivalent about completing his journey home than would be expected of him. The manifestations of this ambivalence in his behavior upon arriving at Ithaka is also explored in the final chapters.
Insights Into Leptopilina Spp. Immune-Suppressive Strategies Using Mixed-Omics And Molecular Approaches, Brian Wey
Dissertations, Theses, and Capstone Projects
Host-parasite interactions influence the biology of each over the course of evolution. Parasite success allows for the passage of potent virulence strategies from generation to generation. Host success passes stronger immunity and resistance strategies to the following generations as well. Only by studying both partners within their natural contexts can we begin to understand the relationship between the two and how immune mechanisms and virulence strategies interact as a molecular arms race.
In this work, we focus on a natural host-parasite pair, the Drosophila-Leptopilina model. Leptopilina species are parasites of several fruit fly species, including Drosophila melanogaster. This model …
Dancing Through Time: A Biographical Look On The Evolution Of Tap Dance, Jaimie Cranford
Dancing Through Time: A Biographical Look On The Evolution Of Tap Dance, Jaimie Cranford
Dissertations, Theses, and Capstone Projects
A uniquely American art form, tap dance has often been misrepresented and under-appreciated when positioned alongside other dance forms. This is largely due to the form’s racialized history, which builds upon contributions from African-American culture. Unlike other dance forms, which stem from white European traditions, tap dance evolved out of a necessity for cultural preservation as enslaved Africans adapted to life in America. As tap dance evolved, its association with slave culture led to it not being taken seriously; if anything, tap dancers were viewed simply as “entertainers” – certainly not as artists. Using a biographical lens, this work looks …
The Different Components Of Active Shooter Incidents: Examining The Co-Occurrence Of Offender And Incident Characteristics, Jeffery R. Osborne
The Different Components Of Active Shooter Incidents: Examining The Co-Occurrence Of Offender And Incident Characteristics, Jeffery R. Osborne
Dissertations, Theses, and Capstone Projects
The present dissertation examined 198 United States single-offender active shooter incidents and thematically differentiated cases based on 1) offender backgrounds, 2) precipitating stressors, 3) offender routine activity, 4) crime scene location, and 5) incident characteristics. Doing so contributed to the increasing number of studies that have stressed the importance of creating empirically-based models to better understand active shooter incidents and the offenders who are responsible. To structure this investigation into active shooter incidents, concepts within Environmental Criminology and Crime Analysis were paired with analytical methodologies seen in Offender Profiling and Investigative Psychology research.
The findings illustrated that offenders could be …
Using The Marcus Inverted Region And Artificial Cofactors To Create A Charge Separated State In De Novo Designed Proteins, Eskil Me Andersen
Using The Marcus Inverted Region And Artificial Cofactors To Create A Charge Separated State In De Novo Designed Proteins, Eskil Me Andersen
Dissertations, Theses, and Capstone Projects
To create an efficient de novo photosynthetic protein it is important to create long lived charge separated states. Achieving stable charge separation leads to an increase in the efficiency of the photosynthetic reaction which in turn leads to higher yields of end products, such as biofuels, electrical charge, or synthetic chemicals. In an attempt to create charge separated states in de novo proteins we hypothesized that we could engineer the free energy gaps in the proteins from excited primary donor (PD) to acceptor (A), and A back to ground state PD such that the forward electron transfer (ET) would be …
Modeling And Analysis Of Affiliation Networks With Subsumption, Alexey Nikolaev
Modeling And Analysis Of Affiliation Networks With Subsumption, Alexey Nikolaev
Dissertations, Theses, and Capstone Projects
An affiliation (or two-mode) network is an abstraction commonly used for representing systems with group interactions. It consists of a set of nodes and a set of their groupings called affiliations. We introduce the notion of affiliation network with subsumption, in which no affiliation can be a subset of another. A network with this property can be modeled by an abstract simplicial complex whose facets are the affiliations of the network.
We introduce a new model for generating affiliation networks with and without subsumption (represented as simplicial complexes and hypergraphs, respectively). In this model, at each iteration, a constant number …
Transcending Absence, Transforming Presence: Undocumented Migrants And The Navigation Of Forced And Chosen Space, Daniel Bloch
Transcending Absence, Transforming Presence: Undocumented Migrants And The Navigation Of Forced And Chosen Space, Daniel Bloch
Dissertations, Theses, and Capstone Projects
By its very nature, undocumented migration challenges the notion of set, static borders, at once rendering them transcend-able while also throwing into stark relief the power and control exercised by the state over undocumented migrants along the arc of their journeys. Two main questions guide my analysis: 1) How are migrants forced to enter and navigate geographic space and zones of exclusion? and 2) How do migrants subvert enforced spaces – often categorized by limbo and uncertainty – both by marking them with their presence and by creating alternative spaces? I consider two compelling examples: In Chapter One, using the …
Varieties Of Transnational Life: Brazilian Nikkeis’ Changing Cross-Border Ties With Two Homelands, Hiroyuki Shibata
Varieties Of Transnational Life: Brazilian Nikkeis’ Changing Cross-Border Ties With Two Homelands, Hiroyuki Shibata
Dissertations, Theses, and Capstone Projects
This dissertation explores the varieties of Brazilian Nikkei’s – Japanese emigrants to Brazil and their descendants – transnational lives throughout a century of their migration history. I propose an interactive process approach to migrant transnationalism to understand the divergence of Brazilian Nikkeis’ transnational lives between their two homelands, Japan and Brazil. First, I focus on the four macro-institutional contexts: 1) positions and development patterns of sending and receiving states within the international state system; the infrastructural power of states, more concretely 2) the diasporic bureaucracy of sending states and 3) the incorporative power of receiving states; and 4) the mobilizing …
Mobile Practices And The Production And Curation Of Pottery: A View From The Ancient Southern Russian Steppe Using Portable Methods Of Investigation, Nicole A. Rose
Dissertations, Theses, and Capstone Projects
The southern Russian steppe is located in an intermediary position between the Caucasus, Lower Don and Lower Volga steppe, between which peoples, goods, and technologies often moved throughout prehistory, likely facilitated by small scale seasonal movements and occasional migrations by mobile pastoralists. Conducted in collaboration with the Steppe Archaeological Expedition of the State Historical Museum’s unfolding research on temporary pastoral camps in the Sal-Manych region of the Rostov oblast and Republic of Kalmykia, this dissertation focused on the production and curation of pottery in contexts associated with the emergence and subsequent development of mobile pastoralism from the late fifth millennium …
Encoding And Perception Of Voicing And Aspiration In Native And Non-Native Listeners In Quiet And In Background Noise, Reethee Antony
Encoding And Perception Of Voicing And Aspiration In Native And Non-Native Listeners In Quiet And In Background Noise, Reethee Antony
Dissertations, Theses, and Capstone Projects
The perception and encoding of voice cues in consonants have been well studied, whereas there has been relatively little research on aspiration. The current study examined the encoding and perception of aspiration and voicing in Hindi, American English, and Tamil listeners when relevant cues were and were not degraded by noise. This study is novel because of the inclusion of aspiration, the language groups, inclusion of noise masking, and inclusion of auditory evoked potentials (in addition to behavioral testing).
The first aim was to determine whether language groups for whom aspiration and/or voicing is phonemically contrastive show better perception and …
Between Kurdistan And Damascus: Kurdish Nationalism And Arab State Formation In Syria, Alexander K. Mckeever
Between Kurdistan And Damascus: Kurdish Nationalism And Arab State Formation In Syria, Alexander K. Mckeever
Dissertations, Theses, and Capstone Projects
Since the fall of the Ottoman empire, Kurdish nationalism has developed as an ideology within a regional state system where Kurds lack national representation or recognition. This ideology has manifested itself into a fractured movement where the contemporary state borders that separate the Kurdish population at large have proven to be both a limiting and a creative factor. This thesis examines the history of Kurdish nationalism in Syria with a focus on both the local context as defined by Syria’s borders in addition to the broader region, for the politics of Kurds in Syria have clearly been shaped by interactions …
Spilling The Tea In Bilingual Latinx New York City Department Of Education School Social Workers: Towards Entre Nos, Cindy M. Bautista-Thomas
Spilling The Tea In Bilingual Latinx New York City Department Of Education School Social Workers: Towards Entre Nos, Cindy M. Bautista-Thomas
Dissertations, Theses, and Capstone Projects
Social workers play an important role in schools. There are about one million children enrolled in the New York City Department of Education(NYCDOE) school system, across 1,843 schools (New York City Department of Education, 2020). Of those students, the largest demographic group is the Latinx population, which has been increasing steadily since 2011. Therefore, there is an urgent need not only to increase the numbers of culturally responsive bilingual Latinx social workers, but also to understand their professional experiences. In order to address this gap in knowledge, the roles of bilingual Latinx school social workers as culturally responsive practitioners in …
When Is A Sandwich Too Much? A Critical Look At Teenage Parenthood And Its Impact On The Lives Of Their Parents, Shirley P. Grant
When Is A Sandwich Too Much? A Critical Look At Teenage Parenthood And Its Impact On The Lives Of Their Parents, Shirley P. Grant
Dissertations, Theses, and Capstone Projects
The transition into early parenthood also implies a shift to early grandparenthood for the parents of teenage parents. The stigmas and stereotypes associated with teenage pregnancy and parenthood are also experienced by their parents for the decisions their children have made. Furthermore, some of these grandparents are caregivers to aging parents while also parenting their younger children. These people, recently called, “the club sandwiched” generation, appear to be experiencing physical, social, economic, and psychological impacts because of their responsibilities of caring for three generations but have not yet received much attention in academic literature. Teenage pregnancy can affect any family. …
Emulating The "Country Fiddler": A Performance Analysis Of Fiddle Parodies And Impressions In Charles Ives's Second Violin Sonata, Emily Vold Weiss
Emulating The "Country Fiddler": A Performance Analysis Of Fiddle Parodies And Impressions In Charles Ives's Second Violin Sonata, Emily Vold Weiss
Dissertations, Theses, and Capstone Projects
In his violin sonatas, Charles Ives frequently parodies fiddling style, both through overt quotes of fiddle tunes, as well as inventive compositional devices that mimic the fiddler’s style of bowing, ornamenting a melody, or generally rustic performance. Given the breadth of these fiddling allusions, it is important that violinists who perform Ives’s sonatas understand the distinctive aesthetics of fiddle performance, including the numerous ways in which it diverges from classical performance. In this dissertation, I survey pedagogical writings on fiddling, notated tunes, and recorded fiddling performances in an effort to characterize the performance practices of fiddlers from Ives’s native New …
School Recess And Changes To Children's Play Opportunities In New York City, Keyonna Hayes
School Recess And Changes To Children's Play Opportunities In New York City, Keyonna Hayes
Dissertations, Theses, and Capstone Projects
The policy, No Child Left Behind Act (NCLB) of 2001 in US public schools was designed to improve how children learn and test in schools, but it has resulted in the decline or removal of recess from most schools. This thesis examines two important issues. The first issue is to assess the play opportunities that public elementary schools offer to children, in terms of both the time available for recess and the quality of the spaces and resources for play during recess. The second issue is to learn, alongside the question of the quality of school recess, how parents’ work …
Producing Movement Space In New York City's Solidarity Economy, Lauren Taylor Hudson
Producing Movement Space In New York City's Solidarity Economy, Lauren Taylor Hudson
Dissertations, Theses, and Capstone Projects
This is a project about how New Yorkers are sharing time, space, resources, and risks to meet their collective needs. To these practitioners the interlocking methods of collective production, use, distribution, and surplus allocation unite to form a ‘Solidarity Economy’ (SE) strengthened by values of cooperation, social justice, ecological sustainability, and mutualism. This work takes many forms, from cooperative businesses, to collective housing, to community gardens—each with their own discrete histories. One thing remains common throughout: In New York City, those who use ‘Solidarity Economy’ as a framework for their work, do so to communicate a shared social and political …
How Psychotherapists Practice In The Digital Era, Josh Weinstein
How Psychotherapists Practice In The Digital Era, Josh Weinstein
Dissertations, Theses, and Capstone Projects
The digital era, marked by digital devices connected via high speed data networks, has altered human experience in profound ways over the past 40 years. The potential for novel forms of human relating and fulfillment of desire has led to myriad changes in behavior, thought and unconscious activity. While many adapt or thrive in expanded reality, for some, the digital can be context, source and/or location for psychological affliction. When those who suffer seek psychological relief, how psychotherapists listen for, conceptualize and work with the effects of the digital matter a great deal. While theoretical and quantitative research literature exists …
From Object To Icon: The Unpredictable Path To Everlastingness, Donna M. Desideri
From Object To Icon: The Unpredictable Path To Everlastingness, Donna M. Desideri
Dissertations, Theses, and Capstone Projects
This thesis explores how a squeaky-clean object transformed into a girl-next-door icon and became a role model for generations to come. And in an industry built on illusions and dreams, reality wore many masks.
Still in its beginning stages and looking to sell tickets, the motion picture industry needed to reconstruct its current downscale public image by presenting a much-improved polished and upscale public image to audiences, all while silencing contradictory images and information. Appealing to a middle-class sensibility to boost this new public image gave the motion picture industry the acceptance it was seeking. By marketing to middle-class audiences, …
The Lodge In The Wilderness: Ecologies Of Contemplation In British Romantic Poetry, Sean M. Nolan
The Lodge In The Wilderness: Ecologies Of Contemplation In British Romantic Poetry, Sean M. Nolan
Dissertations, Theses, and Capstone Projects
This dissertation argues that contemplation is often overlooked in studies of British Romantic poetry. By the late 1700s, changing commercial and agricultural practices, industrialism, secularization, and utilitarianism emphasizing industriousness coalesced to uproot established discourses of selfhood and leisure, and effected crises of individuation in Romantic poetry and poetics. Closely reading poems and writing about poetry composed between the 1780s and 1830s by William Cowper, George Crabbe, Robert Bloomfield, Charlotte Smith, William Wordsworth, Samuel Taylor Coleridge, and John Stuart Mill, I probe the relationship between aesthetic, ethical, and emotional responses to depictions of toil, idleness, and leisure. I argue that ecologies …
Exploring The Effects Of Coworker Ostracism On Feedback Inquiry And Voice: The Mediating Role Of Proactive Motivation, Ethan G. Rothstein
Exploring The Effects Of Coworker Ostracism On Feedback Inquiry And Voice: The Mediating Role Of Proactive Motivation, Ethan G. Rothstein
Dissertations, Theses, and Capstone Projects
Coworker ostracism occurs when employees perceive that their coworkers are ignoring or excluding them. The current work examines how coworker ostracism predicts feedback inquiry and voice, two proactive behaviors important for individual and organizational success. Specifically, I explored whether these relationships are mediated by three proactive motivation states: organizational identification, control appraisal, and positive affect. I also examined whether political skill and perceived organizational support (POS) moderated the relationships between coworker ostracism and proactive motivation states, as well as the proposed indirect effects. I collected data from 309 participants via TurkPrime, using a two-wave lagged design with measurements separated by …