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Immune Cell-Protein Interactions In Alzheimer’S Disease, Kapur Dhami Jul 2022

Immune Cell-Protein Interactions In Alzheimer’S Disease, Kapur Dhami

Dissertations

Misfolded protein aggregates are one of the significant contributing factors in many neurogenerative diseases including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and others. My PhD research project was to study various aspects of amyloid-β peptide, a 40-42-residue peptide and the primary component of the senile plaques found in Alzheimer’s disease (AD) brains. One objective of my research was to purify and characterize the intermediate Aβ42 species using an array of biophysical techniques like size exclusion chromatography, fluorescence assays, circular dichroism, cellular assays, and protein assays. The other major research thrust of my project was to study the role of microglial …


A Managerial Ecosystem For Excellence In Hospital Administration, Denish Gangasingh Jul 2022

A Managerial Ecosystem For Excellence In Hospital Administration, Denish Gangasingh

Dissertations

Major healthcare systems and hospital organizations face a myriad of challenges in today’s business environment, having to provide very complex and more comprehensive medical care with fewer resources. In this study, we investigate determinants of hospital performance in critical dimensions and propose an information infrastructure intended to promote excellence in clinical performance while sustaining a solid financial footing.

Senior executives must be knowledgeable in both business and clinical aspects of hospital administration because their decisions ultimately affect patient care and clinical outcomes. Key performance indicators (KPI) are necessary on both dimensions to inform their decisions. Financial and operational aspects of …


Marching Forward: A Qualitative Examination Of Adapting Enlisted Veteran Leadership Skills In The Corporate Environment, Casey W. Jensen Jul 2022

Marching Forward: A Qualitative Examination Of Adapting Enlisted Veteran Leadership Skills In The Corporate Environment, Casey W. Jensen

Dissertations

planning, resource utilization, and conforming to corporate policies all required adaptation. Veterans primarily adapt their leadership skills through internal and external networking, mentors, coaches, managing and resetting expectations, and understanding light and dark ambiguity. The theoretical contributions of this research are in paternalistic leadership and veteran enlisted research. The practical implications assist veterans in understanding how to adapt and strategies to adapt their skills. In addition, managers and peers may use this research to understand veterans' challenges better when leaving military service. Next, talent acquisition professionals can use this research to better identify military veteran candidates for specific roles and …


Perceptions Of Instructor Caring Behaviors Between English As A Second Language And Non-English As A Second Language Nursing Students, John C. Dike Jul 2022

Perceptions Of Instructor Caring Behaviors Between English As A Second Language And Non-English As A Second Language Nursing Students, John C. Dike

Dissertations

English as a second language (ESL) nursing students have a significantly higher attrition rate and lower National Council Licensure Examination (NCLEX) pass rate than their non-ESL counterparts. Instructor caring behaviors (ICBs) are the ways nursing instructors treat students with respect, taking care to avoid prejudices, stereotyping, and judgments in the teaching-learning process which present prelicensure faculty to grapple with the challenge of effectively meeting the learning needs of both ESL and non-ESL students. The purpose of this cross-sectional, comparative study, guided by Watson's theory of human caring, was to explore the differences in perceptions of ICBs between ESL and non-ESL …


Influences Of 12-Hour Shifts On Unhealthy Eating Habits Of Acute Care Nurses, Ruth Sawdy Jul 2022

Influences Of 12-Hour Shifts On Unhealthy Eating Habits Of Acute Care Nurses, Ruth Sawdy

Dissertations

Shift work is a necessary part of a nurses' work schedule to patients who need 24 hours of continuous care. Eating habits of nurses are influenced by working long hours, not having adequate time to take a meal break, and not having access to healthy food choices which can cause stress and exhaustion and results in weight gain and obesity. The purpose of this quantitative logistic regression analysis, guided by the health belief model and the theory of planned behavior, was to determine if there was a relationship between shift work and the unhealthy eating habits/obesity rates of acute care …


Choices Related To Maximizing Quality Of Life At End Of Life, Theresa Lynn Jul 2022

Choices Related To Maximizing Quality Of Life At End Of Life, Theresa Lynn

Dissertations

Humans, including those residing in the United States, can live in denial of their own mortality. Because of this, futile care is sometimes provided, often at great monetary expense and for little or no return in terms of quality or length of life. At least two opportunities exist for making choices regarding care at the end of life in the U.S.: completing advance directives and choosing hospice care.


An Exploratory Multiple Case Study Of Discipline Practices In A Major Metropolitan Public School District: A Look Into The School To Prison Pipeline, Neil French, Kristin Calvert-French, Phyllis Jackson, Erin King Jul 2022

An Exploratory Multiple Case Study Of Discipline Practices In A Major Metropolitan Public School District: A Look Into The School To Prison Pipeline, Neil French, Kristin Calvert-French, Phyllis Jackson, Erin King

Dissertations

The school to prison pipeline is a phenomenon fed by exclusionary discipline practices that increase the likelihood that a student will have an interaction with the juvenile or criminal justice system at some time in their life; this phenomenon disproportionately affects Black students. Understanding the problem is key to slowing down the school to prison pipeline. This study of a school district in Missouri explores questions about how interpersonal relationships, implicit bias awareness, and school policies influence the learning environment, and how those factors relate to school discipline, which ultimately can lead to the school to prison pipeline. Drawing data …


Relationship Of Leader-Member Exchange On Role Stress And Burnout: A Public Accounting Perspective, Sammie Parsley Jul 2022

Relationship Of Leader-Member Exchange On Role Stress And Burnout: A Public Accounting Perspective, Sammie Parsley

Dissertations

An issue that concerns public accounting firms, both large and small, is that of employee burnout within the workplace. As a service-oriented industry, accommodating client needs is pivotal to long-term success. With that in mind, meeting client demands often means accountants must work long and strenuous hours, an attribute inherent to the industry. Consequently, public accounting firms often find themselves struggling with voluntary turnover as a result of burnout and opportunity for increased financial incentives elsewhere. The busy season in public accounting can be especially difficult, as accountants can find themselves working very long hours for weeks on end. This …


Resilience In Black Mental Health Counselors, Ericka Cables Jul 2022

Resilience In Black Mental Health Counselors, Ericka Cables

Dissertations

Though resilience is a commonly studied variable in different disciplines, there is relatively little research on occupational settings. Researchers take various perspectives in defining resilience as a trait, process, and an outcome. Regardless of how it is defined, it is a vital protective factor for Black mental health counselors who may be significantly impacted by similar experiences, such as racism and racial discrimination, as the Black clients they serve. This dissertation study consisted of two studies utilizing the same data set. In the first study, psychometric properties of a new quantitative instrument, the Race-Based Resilience Scale (RBRS), was constructed to …


Long-Term English Learners In Middle School: Perspectives On Growth In Language Acquisition And Academic Learning, Barbara Doerfler Jul 2022

Long-Term English Learners In Middle School: Perspectives On Growth In Language Acquisition And Academic Learning, Barbara Doerfler

Dissertations

Middle schools in the United States today have a large population of English learners (ELs), and many of them have been educationally labeled as long-term English learners (LTELs). In some middle schools, over half of the ELs in seventh and eighth grades meet the criteria for classification as LTELs. This is especially concerning as these students will shortly be moving on to high school with limited English proficiency, which will continue to affect their academic performance and may limit their choices in higher education and career paths. This study explored the educational experience of LTELs in middle school by seeking …


Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan Jul 2022

Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan

Dissertations

Previous resting-state functional connectivity (rsFC) research has identified aberrant connectivity in several large brain networks in depression, including the default mode (DMN), frontoparietal (FPN), and salience networks (SN). Connectivity of these networks is also related to depressive symptom severity and is affected by cortisol levels. To our knowledge, this is the first study to investigate the effects of acute cortisol administration on rsFC of DMN, FPN, and SN in individuals varying in depression history and severity. We collected resting-state fMRI scans for 74 women with and without a history of depressive disorder after administration of cortisol and placebo using a …


Implementing Recova® To Adjust Estimated Dry Weight In An Outpatient Hemodialysis Clinic, Ayomide Aruwajoye Jul 2022

Implementing Recova® To Adjust Estimated Dry Weight In An Outpatient Hemodialysis Clinic, Ayomide Aruwajoye

Dissertations

Problem: The purpose of this project is to implement the Recova® tool to adjust estimated dry weight supporting interdisciplinary team management of fluid overload in dialysis patients. Fluid overload can lead to high rates of morbidity and mortality. A total sample of 26 hemodialysis patients in an outpatient clinic located in a metropolitan city in a midwestern state was included in the project. Data collected shows there was poor knowledge familiarity with how fluid should be managed in patients suffering from chronic kidney disease. The nurses utilized the Recova tool for a period of 8 weeks to help aid in …


Factors Influencing The Adoption Of Smart-Home Appliances: Users' Perspectives, Prakash Shahi Jul 2022

Factors Influencing The Adoption Of Smart-Home Appliances: Users' Perspectives, Prakash Shahi

Dissertations

Smart appliances will be a significant part of the annual $300 billion smart-home market by 2025. Their use is expected to grow at a compounded annual growth rate of 31% for the foreseeable future. Currently, 12-16% of households use smart-home products in the U.S., including thermostats, TVs, refrigerators, coffee machines, garage door openers, and vision-equipped doorbells. Smart appliances provide significant benefits to us over traditional appliances. Smart appliances simplify our lives by automating various tasks in our homes and allowing us to monitor and control them remotely from our offices, grocery stores, and wherever we may be.

Despite the usefulness …


Maintaining Yoga Practice For Diabetes Control And Prevention, Gina K. Alexander Jul 2022

Maintaining Yoga Practice For Diabetes Control And Prevention, Gina K. Alexander

Dissertations

Type 2 diabetes mellitus affects millions of individuals, representing a vast burden of disease for the national health care system. Yoga practice has demonstrated potential for diabetes control and prevention, yet few yoga-based studies explore factors affecting maintenance of yoga practice over time.

The purpose of this study was to explore factors influencing the maintenance of yoga practice over time, to clarify the relationship between the social environment and yoga practice, and to examine the influence of a yoga intervention over time on the physical activity of adults with or at risk for type 2 diabetes.


The Lived Experience Of Parents Of Children With Special Healthcare Needs On Public And Private Insurance: A Phenomenological Study, Regine P. Reaves Jul 2022

The Lived Experience Of Parents Of Children With Special Healthcare Needs On Public And Private Insurance: A Phenomenological Study, Regine P. Reaves

Dissertations

Due to recent advances in medical technology, the number of children with special healthcare needs (CSHCN) is steadily growing in the United States. CSHCN comprise more than 40% of overall healthcare costs nationwide, even though this group is only comprised of 16% of the U.S. child population. There are significant differences between private and public health plans in terms of cost, adequacy, and parent satisfaction. As an added benefit, some public and private health insurance plans offer nursing care coordination (or nursing case management) services. The purpose of this study was to understand the experiences of parents of CSHCN enrolled …


Differences In Satisfaction Of Nurses Related To Career Track Choice, Joan L. Frey Jul 2022

Differences In Satisfaction Of Nurses Related To Career Track Choice, Joan L. Frey

Dissertations

Master's-prepared nurses from clinical settings across a Midwest state were surveyed to determine factors that signified career choice satisfaction or dissatisfaction. Evaluation and comparison of demographic data and correlation tests were used to assess and contrast individual factors to those of a recent national nursing faculty study. Individual factors were identified, which statistically and significantly correlated career choice to satisfiers and dissatisfiers, based on years in clinical roles. Findings in this study revealed similar age, gender, education levels, and anticipated retirement years for the sample group when compared to a more comprehensive nursing faculty study. Consistencies among groups linked motivation …


The Impact Of Emotional Intelligence On The Leadership Of Chief Human Resources Officers In The California Community Colleges System, Tonya Davis Jul 2022

The Impact Of Emotional Intelligence On The Leadership Of Chief Human Resources Officers In The California Community Colleges System, Tonya Davis

Dissertations

Purpose: The purpose of this phenomenological study was to describe the perceptions of chief human resources officers (CHROs) in the California Community Colleges System regarding the impact of emotional intelligence (EI) on their leadership in four areas: self- awareness, self-management, social awareness, and relationship management.

Methodology: This qualitative phenomenological study described the lived experiences of CHROs as those experiences relate to the impact of EI on their leadership. A random sample was selected from the target population of 24 CHROs located in the Central and Southern Regions of California. The instrumentation used in the study was semistructured interview questions adapted …


Adolescent Depression: Experiences And Meanings Of Being Parented And Parenting, Terri Jean Farmer Jul 2022

Adolescent Depression: Experiences And Meanings Of Being Parented And Parenting, Terri Jean Farmer

Dissertations

Major depression affects up to 40% of U.S. adolescents in mild to severe forms, compromising emotional, academic, and relational functioning, including that of interacting with parents. The purpose of this study was to explore the parent-adolescent relationship during an episode of depression in order to elucidate the adolescent experience of being parented and the parental experience as it contributes to the context of the adolescent. Research questions included: 1) What are the depressed adolescent's meanings and experiences of being parented? 2) How do the meanings and experiences of parenting contribute to the context of the lifeworld of the depressed adolescent? …


The Lived Experiences Of Minority Nursing Students: Perceived Barriers To Success, Strategies For Success, And The Role Of Grit, Sherry Ann Koenigsman Jul 2022

The Lived Experiences Of Minority Nursing Students: Perceived Barriers To Success, Strategies For Success, And The Role Of Grit, Sherry Ann Koenigsman

Dissertations

The education and graduation of minority nursing students is needed to meet the healthcare needs of the people of the United States. However, more minority nursing students are lost to attrition than are white students. The purpose of this study was to seek to understand, from the perspective of the minority nursing students themselves, what barriers they face, their strategies for success, and the role grit plays in their nursing school journey.


Lean Accounting: A Connection To Strategic Partnership & Collaboration Between Management Accountants And Operations Managers, Colleen Mpofu Jul 2022

Lean Accounting: A Connection To Strategic Partnership & Collaboration Between Management Accountants And Operations Managers, Colleen Mpofu

Dissertations

Technological advances, such as automation and artificial intelligence, have transformed the accounting profession. There is a consensus in the academic and practitioner literature that management accountants must move from their traditional role into one that serves as a strategic partner. However, literature that examines how management accountants have moved from this traditional role to one that is more strategic is limited. This study combines concepts from three different literature streams to explore how utilizing lean accounting practices relate to management accountant’s participation in strategic decision making, partnership with operations managers, and overall operational performance in manufacturing firms utilizing a lean …


Predicting The Nclex-Rn Pass Rate At An Associate Degree Nursing Program, Dawne Devoe Olbrych Jul 2022

Predicting The Nclex-Rn Pass Rate At An Associate Degree Nursing Program, Dawne Devoe Olbrych

Dissertations

The National Council Licensure Examination for Registered Nurses (NCLEX-RN) firsttime pass rate for an associate degree in nursing (ADN) program was below the national mean, presenting a problem for graduates who failed the NCLEX-RN and could not enter the workforce as registered nurses. Knowles's assumptions of adult learning, Ebbinghaus's forgetting curve, and Zull's neuroscience research served as the theoretical frameworks for this study. The purpose of this study was to identify which academic and time-lapse variables predict the graduate's first-time passage for the NCLEX-RN. Archived academic records and NCLEX-RN results for all 786 graduates from one ADN program who took …


An Examination Of The Influence Of Select Non-Cognitive Variables On The Intention Of Minority Baccalaureate Nursing Students To Complete A Baccalaureate Nursing Program, Dena B. Evans Jul 2022

An Examination Of The Influence Of Select Non-Cognitive Variables On The Intention Of Minority Baccalaureate Nursing Students To Complete A Baccalaureate Nursing Program, Dena B. Evans

Dissertations

On college and university campuses nationwide, understanding the phenomenon of student retention has become an institutional imperative. The loss of any student is costly to a college or university, resulting in considerable financial loss (Siedman, 2005). For some programs of study, such as nursing, retention is paramount, not only for the institution but for the communities which are served by its graduates. Moreover, retaining minority nursing students is of particular importance because it holds the key to the resolution of a long-standing absence of minority representation in the nursing profession, the nursing shortage and the elimination of health disparities among …


Evaluating Sbirt In A Behavioral Health Urgent Care, Christina L. Williams Jul 2022

Evaluating Sbirt In A Behavioral Health Urgent Care, Christina L. Williams

Dissertations

Background: Adolescent substance use (SU) is a major health concern. Most youth who engage in alcohol and other SU do not meet criteria for SU disorder (SUD). Nonetheless, evidence shows SU during adolescence impacts cognitive, social, and emotional development, increases risk of physical injury, and may progress to SUD in adulthood. Only half of clinicians properly screen adolescents for SU; those identified with SUD often receive no intervention. Screening, Brief Intervention, and Referral to Treatment (SBIRT) is an evidence-based intervention to address this problem. The purpose of this project was to evaluate implementation of SBIRT using CRAFFT 2.1+N, a SU …


Multi-Method Approach To Examining Psychosocial Responses And Reactions To Covid-19 In The Us And China, Fan Li Jul 2022

Multi-Method Approach To Examining Psychosocial Responses And Reactions To Covid-19 In The Us And China, Fan Li

Dissertations

Objective

The purpose is to examine health care providers’ psychosocial responses to COVID-19 in China and the US via exploring relationships among psychological responses and describing experiences of working at the epicenter during the pandemic.

Methods

In manuscript one, a cross-sectional study was conducted in nurse and physician volunteers who provided direct care to COVID-19 patients in Wuhan (volunteers) and those with no COVID-19 contact outside of Wuhan (non-volunteers). A path analysis theoretical model was developed to illustrate the relationships among psychosocial variables and was separately applied to volunteer and non-volunteer groups.

In manuscript two, a cross-sectional study was conducted …


Transition Needs, Challenges, Satisfaction, And Support Strategies Of Newly Hired Nurses In The Clinical Setting, Ric-An Artemio S. Gadin Jul 2022

Transition Needs, Challenges, Satisfaction, And Support Strategies Of Newly Hired Nurses In The Clinical Setting, Ric-An Artemio S. Gadin

Dissertations

With a looming shortage of nurses in the global scenario, there is a deep concern to address the transitioning of newly hired nurses to become skilled nurses who can deliver essential health services without compromising the safety and effectiveness of patient care. There is an urgent need to effectively prepare these new nurses for the transition to bedside clinical practice. This prompted the researcher to identify the transition needs, challenges, satisfaction, and support strategies of newly hired nurses in the clinical setting. This study utilized a descriptive method of research using a validated self-constructed survey questionnaire to elicit responses from …


Remote Learning - The Future Of Education: Effective Instructional Strategies Used By Parent Educators And Recommendations For Building Capacity, Raelene Ferguson Haugen Jul 2022

Remote Learning - The Future Of Education: Effective Instructional Strategies Used By Parent Educators And Recommendations For Building Capacity, Raelene Ferguson Haugen

Dissertations

Purpose: The purpose of this mixed methods Delphi study was to identify the remote learning instructional strategies used by expert Southern California parent educators for implementing the anticipatory set, modeling, checking for understanding, and guided practice elements of Madeline Cheek Hunter’s Instructional Theory Into Practice (ITIP) framework. The study sought to identify how expert Southern California parent educators rated the effectiveness of the remote learning instructional strategies in the aforementioned elements of Hunter’s ITIP framework. Additionally, the purpose was to generate recommendations from expert Southern California parent educators to build capacity in the identified effective instructional strategies.

Methodology: The classical …


Increasing Rooming-In Rates On A Mother Baby Unit, Scotti Manes Jul 2022

Increasing Rooming-In Rates On A Mother Baby Unit, Scotti Manes

Dissertations

Problem: For new postpartum mothers, rooming-in has much evidence-based benefit; yet it is not widely accepted. Recent trends show the standard of care has changed to have newborns cared for in the nursery during parts of the postpartum period. Healthcare providers have unintentionally lacked providing ample education to new mothers regarding the benefits of rooming-in for mothers and newborns.

Methods: For this quality improvement (QI) project, a descriptive observational study design was used to identify if implementing standardized rooming-in education for patients influences rooming-in rates or the rates of exclusive breastfeeding at discharge. Thirteen staff nurses were identified as “champions” …


Visualizing Depressive Symptom Improvement: Implementing The 17-Item Hamilton Depression Rating Scale, Briana Raterman Jul 2022

Visualizing Depressive Symptom Improvement: Implementing The 17-Item Hamilton Depression Rating Scale, Briana Raterman

Dissertations

Visualizing Depressive Symptom Improvement: Implementing the 17-Item Hamilton Depression Rating Scale

Abstract

Problem

Depression, a mental health diagnosis, has affected about 18.5% of adults (Villarroel & Terlizzi, 2020). Ketamine, a medication initially used as an anesthetic, has improved depressive symptoms in individuals struggling with treatment-resistant depression.

Method

This quality improvement (QI) project used the 17-item Hamilton Depression Rating Scale questionnaire to assess depressive symptom changes in patients receiving intramuscular ketamine for treatment-resistant depression. The questionnaire was administered to patients pre-and post-intramuscular ketamine administration. The data was collected on injections one, three, and six on each participant’s set schedule of injections …


An Evaluation Of A Multidisciplinary Implementation Of Evidence Based Practice In Prediabetes, Emily Sisco Jul 2022

An Evaluation Of A Multidisciplinary Implementation Of Evidence Based Practice In Prediabetes, Emily Sisco

Dissertations

Abstract

Problem Over 70% of prediabetic patients progress to full diabetes. There are over 80 million American adults who are diabetic. Diabetes is the costliest chronic disease that often leads to many other health issues.

Methods This QI project utilized a descriptive observational design. Quantitative data was collected via retrospective chart review. Primary data collected was documentation of a patient visit to the registered dietician and the hemoglobin A1c (HbA1c) of patients who followed up in the office after the referral.

Results Eight patients followed up to the office for a second visit (n=8). Four patients did see the registered …


Bee Brains: Dissecting Pollinator Behavior And The Importance Of Plasticity In The Face Of Changing Environments, Rachel Brant Jul 2022

Bee Brains: Dissecting Pollinator Behavior And The Importance Of Plasticity In The Face Of Changing Environments, Rachel Brant

Dissertations

All organisms face environmental variability, and much of contemporary biological research aims to understand the mechanisms allowing organisms to adapt and survive in the face of change. Animals residing in urban habitats face particularly high levels of unpredictability and environmental fluctuation due to changes based upon human desire. Though urban areas are considered relatively novel habitats, numerous species have adapted to city life, mediated through behavioral and physiological plasticity. Native bee species show particularly high species richness and abundance in urban settings, but the mechanisms driving this pattern are poorly understood. In this dissertation, I explore how bees employ plasticity …