Anonymity And Accountability In Secure Messaging, Erin Kenney

Dissertations

Encypted messaging has become more and more prevalent as time moves on, and its benefits in assuring privacy cannot be overstated, but it also brings along with it concerns on how to moderate platforms where all messages are hidden. Message Franking, followed by Traceback systems, addressed these concerns by allowing the sender of a message to be proven when reported, even for forwarded messages in the case of Traceback, however these systems damage the privacy guarantees that originally motivated encrypted messaging to begin with.

In practice, even without those concerns encrypted messaging alone is not enough to prevent the most …

Glass Transition Temperature Of Plga Nanoparticles And The Application In Drug Delivery, Guangliang Liu

Dissertations

The glass transition temperature (T_g) of poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles plays a crucial role in governing molecular mobility, diffusion, and consequently, drug release kinetics. However, the interaction among residual surfactant, drug effect, nanoscale confinement, and release medium on T_g remains insufficiently characterized. This study aims to bridge this gap by correlating the thermal behavior of PLGA nanoparticles with their drug release behavior under physiologically relevant conditions.

In the present study, PLGA nanoparticles were synthesized using both nano-emulsion and surfactant-free nano-precipitation approaches. The influence of residual surfactants - poly(vinyl alcohol) (PVA) and didodecyldimethylammonium bromide (DMAB) - was systematically …

Membrane-Engineered Nanotherapeutic Platforms For Drug Delivery: Hollow Fiber Membrane Synthesis Of Lipid Nanoparticles, Biomimetic Nanocarriers, And Nanobubbles, Zhixiang Liu

Dissertations

Lipid-based nanocarriers have emerged as a cornerstone technology for RNA therapeutics, enabling effective intracellular delivery for applications ranging from vaccination to gene regulation. However, current manufacturing approaches, particularly microfluidic-based platforms, face inherent limitations in scalability, throughput, and structural tunability due to their reliance on confined channel geometries and restricted mixing architectures. Addressing these challenges requires fundamentally new strategies that decouple nanoparticle formation from traditional microscale flow constraints while maintaining precise control over physicochemical properties.

This dissertation presents a comprehensive framework for the design, engineering, and application of advanced lipid-based nanocarriers, centered on a hollow fiber membrane (HFM)—assisted nanopore-mediated assembly platform. …

Parameter Density Estimation For Cardiac Electrophysiology Models Using Data Consistent Deep Learning, Michael Luo

Dissertations

Mathematical models of biological rhythms and excitable systems can provide insights into mechanisms underlying cardiac electrical dynamics. However, estimating the parameters of these models from experimental observations is often difficult due to noise, heterogeneity, and unobserved variables. For example, in an electrocardiogram (ECG) recording, information about the electrical properties of different regions of the heart is compressed into a single voltage trace. Additionally, variability within these signals may contain important information about population heterogeneity, regional differences in electrophysiology, and time-dependent modulation.

This dissertation develops, explores, and evaluates methods that perform feature-based distributional inference for complex nonlinear dynamical systems. The objective …

Transcranial Ac Modulation Of Cerebellar Nuclear Activity In Awake Animals, Nuran Kavakli

Dissertations

Entrainment of cerebellar nuclear (CN) cells via cerebellar transcranial alternating current stimulation (ctACS) has been reported in animals under ketamine/xylazine anesthesia. Our main objective was to demonstrate modulation of CN activity in unanesthetized, freely moving animals using ctACS. Multi-channel carbon-fiber electrodes were implanted into the interpositus nucleus for recording multi-unit (MU) activity, and thin-film electrodes were implanted subcutaneously over the posterior cerebellum for stimulation. A frequency-domain-based metric was developed to quantify modulation from MU signals. The results demonstrated modulation in a wide range of frequencies (4 Hz-300 Hz) as in anesthetized animals. In contrast, the amplitude of the peak in …

Task Sharing Of Tele-Mental Health Interventions In Primary Care: Formative Assessment Using Implementation Science, Frances Chu

Dissertations

Primary care frequently cares for patients with mental health concerns. Tele-mental health (TMH) interventions are becoming used as alternatives to the traditional methods of mental health care delivery. However, implementation of these interventions has met with uneven implementation success. Task sharing is a care model that trains less specialized health care workers to perform tasks typically done by specialized health care workers. Few studies have examined the combination of Task sharing and TMH intervention for the management of mental conditions. This dissertation project utilized implementation science methodology for formative assessment of task sharing of TMH interventions. The goals of the …

Positioning Rights And Duties For Parent Representation At The Cac For Special Education Table: A Result Of Cbpar, Summer Girgis

Dissertations

This dissertation explores the impact of parents’ social justice advocacy on their local Community Advisory Committee for Special Education (CAC) policy and practice. While California state mandates a CAC that includes parent-district collaboration in decision-making, several Southern California districts oppress eager voices and willing participants. On the premise that policy implementation was absent and that parents wanted to exercise their right to implementation, this study aimed to identify: RQ1) how families of students with disabilities communicate their wants and needs to districts and SELPA personnel, and RQ2) the critical elements or components of establishing a collaborative partnership. With eight mothers …

“I Have A Voice”: Bridging The Communication And Sensemaking Gap Between Restorative Justice Practice And Program Implementation, Stefan Cocorelis

Dissertations

Restorative justice (RJ), a philosophy, practice, and movement inspired by local, largely Indigenous traditions, has increasingly been introduced in modern criminal justice systems as an alternative process to more comprehensively address harmful incidents, heal harms, and meet victim’s needs. While RJ implementation growth is encouraging for its advocates, there remain significant questions around formalized RJ practice. Specifically, little is known about the decision-making process in implementing and administering RJ programming within criminal justice. This dissertation aimed to contribute to the understanding of RJ practice and implementation efforts within criminal justice systems by putting emphasis on practitioners already working directly in …

Moving Toward Humanization In Education: Teacher Models In K-12 Settings, Juan Carlos Marques

Dissertations

ABSTRACT Current pedagogical initiatives—social emotional learning (SEL), restorative practices

(RJ), and positive behavioral interventions and supports (PBIS)—aim to improve students’ relationships at school, but they often fail to address the hegemonic ideologies that sustain inequitable disciplinary practices and outcomes for minoritized students. Humanization, which centers the dignity and lived experiences of children, is a needed critical component. Drawing from the work of scholars such as Freire and del Carmen Salazar, this study sought to learn from the experiences of teachers who engaged humanizing practices. Grounded in disability critical race theory (DisCrit), this study examined how teachers used a humanizing approach …

Decision-Making In Early-Stage Startups: How Venture Capitalists And Angel Investors Evaluate Uncertainty, Andrew M. Pence

Dissertations

The purpose of this dissertation is to examine how venture capitalists (VCs) and angel investors (AIs) make investment decisions regarding early-stage startups. Using an Interpretative Phenomenological Analysis (IPA) framework—consisting of three core components: phenomenology, hermeneutics, and idiography—this study draws upon three decision-making models: the Rational Actor Model (RAM), the Heuristics and Biases model (H&B), and the Naturalistic Decision-Making model (NDM) to explore what motivates VCs and AIs to choose, for instance, “Company A over Company B.” Semi-structured interviews were conducted with 10 experienced venture investors to examine how they evaluate risk, assess founders and teams, and navigate the persistent uncertainty …

Generative Ai And Student Engagement, Motivation, And Learning: Exploring The Use Of Generative Ai In Higher Education Online Courses, Jeffrey L. Simmons

Dissertations

ABSTRACT

The rapid emergence of Generative AI (GenAI) large language models (LLMs) such as ChatGPT in higher education has left many institutions unprepared to assess their potential benefits and risks. This mixed-methods study examined how ChatGPT and Google’s NotebookLM were integrated into online course development and delivery at a small private nonprofit university in California, and assessed their perceived impact on student engagement, motivation, and learning.

Data were collected from post-course Likert-scale surveys completed by students across three online master’s-level courses and from pre-course prediction surveys by instructors in the two NotebookLM courses. Quantitative analyses included one-sample t-tests against a …

Elevating Voices: Exploring The Impacts And Experiences Of Required Workplace Dei Training, Marika Barto

Dissertations

Mandatory diversity, equity, and inclusion (DEI) training is a common element institutional DEI initiatives in their response to dismantling racial inequity in government organizations; yet, the lived experiences of racially marginalized participants remain critically underexamined—particularly in government settings, where the bureaucratic structures implementing these trainings are themselves racialized. This research was conducted during one of the most politically hostile environments for DEI work in recent memory. Federal executive actions in 2025, specifically the “Bondi memo,” directed entities subject to federal antidiscrimination laws to cease DEI practices, creating immediate chilling effects that directly impacted this study and reminded us that the …

Embodied Leadership And Conditional Legitimacy: Critically Conscious Male Leaders Navigating Systems Of Power, Luis A. Legaspi

Dissertations

Leadership is not a neutral concept; it is shaped by overlapping systems of power, including empire, whiteness, neoliberal capitalism, and cisheteropatriarchy. These interlocking systems influence how leadership is defined, recognized, and legitimized, often privileging particular identities and forms of authority. The persistent underrepresentation of people of color, women, and queer individuals in positions of leadership reflects how dominant conceptions of leadership remain closely aligned with historically entrenched structures of power.

This critical narrative inquiry study examines how men, who disproportionately occupy positions of social and institutional authority, make meaning of masculinity, power, and leadership within these systems. Drawing on relational …

Burning Out: A Narrative Exploration Of The Adaptive Challenge And Scaffolds Built Toward Sustenance Among Immigrant Rights Activists In San Diego County, Anna C. Runion

Dissertations

Activist burnout has been identified as one of the greatest threats to social movement sustainability, and the lived experience of paid immigrant rights activists remains undertheorized. This narrative inquiry explored activist burnout among 10 San Diego County immigrant rights activists, revealing how this community understands burnout, what factors contribute to its production, and how activists sustain themselves within it. Using Clandinin and Connelly’s (2000) narrative inquiry methodology, the researcher conducted in-depth individual interviews with ten activists representing a range of intersectional identities and roles. Narrative profiles were analyzed through holistic narrative reading, narrative reporting, structural and emergent coding, and cross-narrative …

Investigating The Impact Of Employment And Demographic Factors On Health Among Bereaved Adults: A Quantitative Approach, Dorothy L. O'Hagan

Dissertations

ABSTRACT

Although the death of a loved one is a universal experience, grief and bereavement may affect employees in the workplace. Prior research on grief and bereavement in the workplace has been largely qualitative. Little attention has been given to how bereavement, employment-related factors, and demographic characteristics are associated with health among working-age adults. The Georgia Behavioral Risk Factor Surveillance System (BRFSS) offered a large dataset for examining these relationships.

This retrospective, exploratory, correlational quantitative study used the 2019 and 2022 Georgia BRFSS datasets to examine self-reported health among bereaved and non-bereaved adults ages 18 to 64. Analytic samples included …

Compassion At The Core: Reimagining Schools As Centers Of Human Flourishing Through Youth-Led Action Research, Tara S. Waudby

Dissertations

In an increasingly competitive and standardized world, student wellbeing is a growing priority in K-12 education, alongside an emerging focus on human flourishing. While not commonly paired with wellbeing science, compassion is gaining prominence as an important systemic mindset. Focusing on compassion in schools cultivates attitudes of caring, openness, generosity, concern for others, and concern for the environment, leading to positive impacts on organizational culture and learning. This points to a broader question about what it means for students and communities to flourish. However, it is unclear how compassion is experienced in the lives of students. A common solution has …

Rainbow Promises, Uneven Promises: Framing Lgbtqia+ Educational Policy And Possibility In Education, Gerardo Lorenzo-Saucedo

Dissertations

Despite the expansion of LGBTQIA+ inclusive policies in K-12 education, disparities in students’ experiences with safety and belonging persist. This qualitative case study examines how such policies are interpreted and enacted within a high school and district in Southern California, and how these processes shape LGBTQIA+ students’ experiences.

Guided by ecological systems theory, queer theory, and multiple streams theory, this study conceptualizes policy implementation as a dynamic and socially constructed process influenced by power, ideology, and institutional context. Data were collected through interviews, document and artifact analysis, and observations, with analysis that used a multi-phased coding procedure.

Findings revealed that …

A Praxis Of Transformative Care: Centering Historically Resilient Students At A Pwi, Tanaisha Coleman

Dissertations

Campus cultural centers frequently treat student resilience as an individual struggle rather than a collective responsibility, obscuring systemic failures. At a predominantly white institution (PWI), historically resilient students, those from diverse backgrounds who have historically endured the structural load of institutional exclusion, carry the compounded weight of navigating systemic barriers while driving institutional change. This qualitative study disrupts traditional narratives of surviving and thriving to examine how undergraduate students constituting a student advisory committee (SAC) coconstructed critical resilience rooted in transformative and collective care.

Using community-based participatory research (CBPR), this study positions students as coarchitects of their institutional experiences. Over …

Reclamando Corazón Y Voz: Latinas Speak Their Truth Through Plática As Resistance In California Community College Learning Disabilities Assessments, Maricela Becerra

Dissertations

Although California Community Colleges (CCCs) offer learning disability (LD) assessments to determine eligibility for academic accommodations, for Latina students navigating converging forces of race, gender, language, citizenship, and ableism, these assessments often surface unspoken histories of harm. This study advanced Chicana feminista DisCrit (CFDC), extending disability critical race theory through Chicana spirituality and cultural intuition to examine possibilities when an educadora situates assessments in a plática grounded in consideración—respectful, relational, and unhurried care.

Rooted in Chicana feminist pláticas methodology and authored from the positionality of a disabled Latina scholar–practitioner, this qualitative decolonial dissertation explored how Latina students reflected on …

Learning Through Lowriding: Knowledge In The Garage, Bianca Elisa Arellano

Dissertations

Lowriding culture has long been situated at the margins where state-sanctioned criminalization processes delegitimize the intellectual agency of lowriders, rendering their knowledge systems institutionally illegible. This dissertation argues that such epistemic invisibility denies lowriders the agency to define their own intellectual contributions, and it reclaims lowriding as a site of profound resourceful innovation. Grounded in Chicana feminist epistemologies, the study theorizes how nepantla—the process of navigating and living at the margins—works alongside rasquachismo, the working-class sensibility through which constraint becomes a site of knowledge production, to frame lowriding in Chicanx San Diego communities as an embodied tension where subversive, resourceful …

For My Oklahomies: Educators’ Perspectives On Policy, Public Discourse, And Professional Wellbeing, Cassandra Herndon

Dissertations

This critical qualitative study examines how ideologies rooted in ultra-conservative movements shape the professional lives of Oklahoma K–12 educators, and how they maneuver, resist, or accommodate ideological forces within a climate of surveillance and professional delegitimization. Grounded in critical social theory and drawing on Foucault (1977) and Leonardo (2003), the study applies a recontextualized model of transformational resistance (Hannegan-Martinez et al., 2024) to analyze educators’ acts of agency within a restrictive policy landscape.

Drawing on semi-structured interviews with eight Oklahoma K–12 teachers and administrators, this study employs critical narrative inquiry alongside reflexive thematic and critical policy analysis to ask: (1) …

Who Gets To Be Taken Seriously? Three Atypical Scholars Navigate Doctoral Education At The Intersections Of Race, Neurodivergence, And Veteran Identity, Sr. Richard De La Garza

Dissertations

As a first-generation, neurodivergent, Mexican American/Chicano veteran, I entered the University of San Diego's doctoral program having had experiences that most institutional intake processes would label as risk factors. The Findings chapter of this dissertation begins by describing those experiences—not as a confession, but as the foundation for a systematic inquiry into how doctoral legitimacy is produced, withheld, and defended. The description of my life experiences is followed by a discussion of the doctoral journeys of two other study participants who also were atypical doctoral candidates.

The central argument being advanced is this: What higher education calls "fit," "rigor," and …

Heat Shock Factor 1 Signaling: A Novel Pathway Implicated In Rett Syndrome Pathophysiology, Sonia Gonzalez

Dissertations

Rett syndrome (RTT) is a severe neurodevelopmental disorder that is associated with loss-of-function mutations in the methyl-CPG binding protein 2 (MECP2) gene. There are limited therapeutic options to address the wide range of social, cognitive, motor, and respiratory symptoms that patients experience throughout their lifetime. To identify novel therapeutic targets, we leveraged a rare form of RTT known as MeCP2-mutation-negative or atypical RTT. Traditionally, RTT is first diagnosed clinically and then confirmed through the identification of mutations in the MECP2 gene. However, ~5% of RTT patients are found to be MeCP2-mutation-negative (atypical), despite sharing overlapping symptomology with typical RTT. We …

A Community College Entry Apparatus, Ann Knezetic

Dissertations

This study explores the conceptualization, enactment, and navigation of a community college entry apparatus. This research views these questions through a single institution case-study, with 17 participants - eight faculty/staff and nine students. Each participant groups brings a distinct view as faculty/staff conceptualize and enact entry as students navigate and experience entry. Findings illuminate how faculty/staff conceptualize entry through offices or programs while students experience entry through their needs being met. Further, these findings complicate entry, particularly in the ways students experience entry multiple times during their college career such as when moving locations across a multi-campus college or when …

Exploring Counselors’ Perceived Preparedness For Private Practice Business Oriented Responsibilities, Corey L. Hancock Jr.

Dissertations

ABSTRACT

The purpose of this study is to understand how fully licensed counselors who graduated from CACREP-accredited programs and did not receive formal business training during graduate school make sense of their preparedness for the business responsibilities of private practice. This study was informed by the theoretical frameworks of relational-cultural theory (RCT; Jordan, 2017) and transformative learning theory (TLT; Mezirow, 1991). Participants were fully licensed counselors with a masters or doctoral degree from a CACREP-accredited counseling program and owned a private practice. Seven participants (n = 7) were included in the study, participating in 60-90 minute semi-structured interviews. An …

Exploring Intimate Partner Relationship Satisfaction Among Women Who Have Experienced Discrimination And Childhood Trauma, Rachel L. Gaglio

Dissertations

Objective: Connections may exist between intimate partner relationship satisfaction outcomes and experiences of childhood trauma and discrimination among women. The majority of existing research highlights individual trauma impacting relationship satisfaction that includes military experience, childhood trauma, domestic violence, and sexual assault, yet there is a gap in research which expands on both childhood trauma and discrimination endured among women in relation to intimate partner relationship satisfaction outcomes, as they relate to intimacy and closeness and resolving conflict and arguments. The present study explored the links between childhood trauma and discrimination experienced by women and their connection in intimate partner relationship …

Mllt1 Is Required To Maintain B-Lymphopoiesis, Janani Prakash

Dissertations

MLLT1 (also named ENL) is an epigenetic reader protein that binds to crotonylated or acetylated lysine residues of histone 3 through its N-terminal YEATS domain. Positive and negative regulatory complexes compete for binding to C-terminal MLLT1, and promote transcription elongation (SEC, Super elongation complex; DOT1L) or transcriptional repression (PRC1, Polycomb repressive complex 1). MLLT1 was initially identified as a chromosomal translocation partner to MLL(KMT2A) in a subset of MLL-rearranged leukemias. MLL-ENL fusion protein causes both lymphoid (predominantly B-ALL) and mixed lineage leukemias. MLLT1 has been implicated in leukemic stem cell survival in MLL-rearranged cell lines but its role in normal …

Lay Presidents In Jesuit Higher Education: How Ajcu Lay Presidents Learn About, Articulate, And Express Jesuit Mission And Identity, Carl Joseph Caceres

Dissertations

Since the year 2000, over the course of the past quarter century, lay presidents went from being an emerging phenomenon to becoming the majority of presidents in the Association of Jesuit Colleges and Universities (AJCU). Lay presidents are now the norm and no longer the exception, as 24 of the 28 institutions of the AJCU are now lay led. This qualitative research study intended to explore how lay presidents of the Association of Jesuit Colleges and Universities (AJCU) in the United States who have been at their current institution for at least three years, came to learn about Jesuit mission …

Underlying Mechanisms In The Relationship Between Ptsd And Irritable Bowel Syndrome, Jillian B. Heymann

Dissertations

Current bodies of knowledge support the relationships between posttraumatic stress disorder (PTSD) and irritable bowel syndrome (IBS), pain catastrophizing and PTSD, and pain catastrophizing and IBS. However, much less is known regarding how pain catastrophizing influences the relationship between PTSD and IBS. Additionally, while correlations between some demographic and trauma-related symptomatology have been elucidated in the relationship between PTSD and IBS, their impact as potential moderators on the relationship between PTSD and IBS has yet to be fully examined. Examining a student sample from a large midwestern university, the present study aimed to investigate the potential mediating and moderating roles …

A Trinity Of Forces: A Critical Investigation Of The Intersection Of Lived Experience, Jesuit Secondary Education, And Corporate Curricula, Bernhard Bruno Walke

Dissertations

This dissertation examines how students' identities and personal experiences shape their encounters with both Jesuit Secondary Education and the Corporate Work Study Program (CWSP). Throughout this qualitative analysis, the researcher will examine how identity, secondary education, and corporate attitudes coexist, overlap, conflict, intersect, and compete with one another. By employing Gloria Ladsen-Billings’s Critical Race Theory (Ladson-Billings & Tate, 1995), Dolores Delgado Bernal and Daniel Solórzano’s contributions to Latinx Criticism (Lat Crit), (Solorzano & Bernal, 2001), Kimberlé Crenshaw’s Theory of Intersectionality (K. Crenshaw, 1989), and Tara Yosso’s Community Cultural Wealth Model (Yosso, 2005), the researcher will examine how students experience “non-linear …