Digital Commons Network^™

Importance Of Vegetation In Tsunami Mitigation: Evidence From Large Eddy Simulations With Fluid-Structure Interactions, Abhishek Mukherjee

Dissertations

Communities worldwide are increasingly interested in nature-based solutions like coastal forests for the mitigation of coastal risks. Still, it remains unclear how much protective benefit vegetation provides, particularly in the limit of highly energetic flows after tsunami impact. The present thesis, using a three-dimensional incompressible computational fluid dynamics model with a fluid-structure interaction approach, aims to quantify how energy reflection and dissipation vary with different degrees of rigidity and vegetation density of a coastal forest.

In this study, tree trunks are represented as cylinders, and the elastic modulus of hardwood trees such as pine or oak is used to characterize …

Continuum Modeling Of Active Nematics Via Data-Driven Equation Discovery, Connor Robertson

Dissertations

Data-driven modeling seeks to extract a parsimonious model for a physical system directly from measurement data. One of the most interpretable of these methods is Sparse Identification of Nonlinear Dynamics (SINDy), which selects a relatively sparse linear combination of model terms from a large set of (possibly nonlinear) candidates via optimization. This technique has shown promise for synthetic data generated by numerical simulations but the application of the techniques to real data is less developed. This dissertation applies SINDy to video data from a bio-inspired system of mictrotubule-motor protein assemblies, an example of nonequilibrium dynamics that has posed a significant …

Deep Hybrid Modeling Of Neuronal Dynamics Using Generative Adversarial Networks, Soheil Saghafi

Dissertations

Mechanistic modeling and machine learning methods are powerful techniques for approximating biological systems and making accurate predictions from data. However, when used in isolation these approaches suffer from distinct shortcomings: model and parameter uncertainty limit mechanistic modeling, whereas machine learning methods disregard the underlying biophysical mechanisms. This dissertation constructs Deep Hybrid Models that address these shortcomings by combining deep learning with mechanistic modeling. In particular, this dissertation uses Generative Adversarial Networks (GANs) to provide an inverse mapping of data to mechanistic models and identifies the distributions of mechanistic model parameters coherent to the data.

Chapter 1 provides background information on …

Development Of Non-Viral Nano-Carriers For Gene Delivery And Covid-19 Vaccines, Zhongyu Li

Dissertations

Gene therapy is one of the most promising medical fields with the potential to effectively advance the treatment of difficult diseases by producing therapeutic proteins or repairing defective gene sequences. However, gene therapy presents severe challenges in delivery including renal clearance, phagocytosis, enzymatic degradation, protein absorption, and cellular internalization barriers, which have been barriers for translation into the clinic. Naked nucleic acids, with their intrinsic negative charge, electrostatically repulse the anionic cell membrane, preventing cellular uptake. Also, they are considered foreign genetic material when introduced into the body and are rapidly cleared by the reticuloendothelial system or degraded by nucleases, …

Development Of Novel Nanocarbon Based Materials And Membranes With Enhanced Biocidal Capabilities For Clean Water Generation, Indrani Gupta

Dissertations

Water scarcity is one of the major challenges facing humanity today, driven by population growth, economic development, and dietary shifts towards more water-intensive animal products. To address this issue, efficient water resource management and recycling of wastewater are essential. However, around 80% of wastewater globally is discharged into water bodies without treatment, posing a risk to ecosystems and human health. Pathogens, or harmful microorganisms, are a primary cause of water impairment and the transmission of waterborne diseases, leading to increased mortality rates. Traditional methods of treating pathogens involve the use of radiation or chemical disinfectants. Nonetheless, these methods have drawbacks, …

Design, Synthesis, Biological And Computational Studies Of Flavonoid Acetamide Derivatives, Daniel Kasungi Isika

Dissertations

Flavonoid compounds (FC) have extensive biological applications through potent antimicrobial, anti-inflammatory, anticancer, antidiabetic, and antioxidant properties. These applications are nevertheless limited by low bioavailability, poor aqueous solubility, enzymatic degradation, rapid metabolism, and fast body clearance. FC show unique structure-activity relationships (SARs) essential in assessing and mitigating the prevalent challenges impeding their applications. These challenges can be addressed by structural modification of the FC through functionalization of the phenolic rings, modification of the ketone group, and modification of the phenolic hydroxyl groups with bioisosteres.

The objectives of this work are to (i) design and synthesize novel flavonoid acetamide derivatives (FADs) and …

Molecular Simulations Of Mechanical Effects Of Adsorption In Gas And Liquid Phases, Alina Emelianova

Dissertations

Fluids adsorbing in nanoporous solids cause high pressures that affect the solids and the properties of the fluids themselves. This work explores the mechanical response of solids to the adsorption of gas and liquid. Chapter 1 outlines the current achievements in investigating the mechanical response of adsorbents to the adsorption process, specifically, the computational approaches to predict adsorption-induced deformation. Chapter 2 introduces the theoretical and computational methods employed in this work. Chapters 3-7 address the design and application of the computational techniques for such prediction in different systems: mesoporous silica, microporous zeolites, and metal-organic frameworks, and Chapter 8 focuses on …

Improving Recognition Of Depression Among The Adult Patients In Psychiatric Settings, Jane A. Ferraris

Dissertations

Depression rating scales may improve depressive symptom identification. At the project site, there was no consistent process for determining patients' depressive symptoms, so an evidence-based solution was sought. The purpose of this quality improvement project was to determine if the translation of Dunlop et al.'s research utilizing the Hamilton Depression Rating Scale-6 (HAMD-6) would impact the rate of identification of depressive symptoms and referrals to psychology for Cognitive Behavioral Therapy (CBT) among adult patients.

Anxiety And Agitation In Adult Patients Admitted To An Emergency Room During The Covid-19 Pandemic, Doris L. Asombrado

Dissertations

Purpose: The purpose of this retrospective correlational study was to identify the relationship between COVID-19 status and the prevalence of anxiety-agitation with select sociodemographic and clinical characteristics in adults admitted to the ED during the pandemic (03/01/2020 through 12/31/2020).

Background: COVID-19 infections combined with the WHO and CDC recommendations to mitigate spread have had deleterious psychosocial and economic outcomes with the risk of subsequent COVID-19 related mental illness. Studies indicate one in three adults experience anxiety or depression.

Methods: This retrospective correlational study reviewed 2,572 psychiatric admissions from a Southern California ED during the pandemic from March 1, 2020 through …

Social Determinants Of Health And Health Confidence, Laura Truman

Dissertations

Purpose/Aims: The purpose of this study was to investigate the relationship among social determinants of health (SDOH), select sociodemographics, and health confidence level in adults receiving care at an urgent care center.

Background/Rationale: To improve overall health and reduce health inequities during a global pandemic and unprecedented rates of inflation, the relevancy and urgency of identifying how patient-level SDOH impact health confidence level are even greater. Extant research indicates a relationship between the number of unmet social needs and low health confidence. Low health confidence predicts poor involvement in self-care and is associated with an increased use of costly health …

Special Education: Inclusion And Exclusion In The K-12 U.S. Educational System, Erik Brault

Dissertations

The U.S. Department of Education defines students with disabilities as those having a physical or mental impairment that substantially limits one or more life activities. Previous research has found that students with disabilities placed in inclusive environments perform better academically and socially compared to students with disabilities who are placed in segregated environments. Yet, we know that inclusion in K-12 general education classrooms across the country is not consistently implemented.

The purpose of this study was to better understand the effects, if any, of general education high school teachers’ personal and professional experiences and knowledge on their attitudes toward educating …

The Development Of The Holistic Pastoral Wellbeing Assessment: A Mixed Methods Study, Timothy Captain

Dissertations

Some pastors are clearly in crisis. Research has indicated that clergy struggle to cope with the stressors of their profession. While pastoral work is overtly spiritual in nature, day-to-day tasks include interactions with God, themselves, congregants, and the world at large. Without multi-dimensional tools to consider their wellbeing, specifically assessments that reflect their worldview and role, pastors may remain unaware of dangerously low levels of wellbeing until they reach a place of crisis. Therefore, in this mixed methods study, the Holistic Pastoral Wellbeing Assessment (HPWA) was developed and tested to offer a validated, useful tool for pastors and those who …

Utilizing New Technologies To Measure Therapy Effectiveness For Mental And Physical Health, Jonathan Ossie

Dissertations

Mental health is quickly becoming a major policy concern, with recent data reporting increasing and disproportionately worse mental health outcomes, including anxiety, depression, increased substance abuse, and elevated suicidal ideation. One specific population that is especially high risk for these issues is the military community because military conflict, deployment stressors, and combat exposure contribute to the risk of mental health problems.

Although several pharmacological approaches have been employed to combat this epidemic, their efficacy is mixed at best, which has led to novel nonpharmacological approaches. One such approach is Operation Surf, a nonprofit that provides nature-based programs advocating the restorative …

Queering Healthcare Equity: Exploring How Two Community Health Centers That Specialize In Lgbtq Healthcare Frame Cultural Competence, Tommy Royston

Dissertations

Despite increased advocacy and funding, significant inequities in healthcare access, quality of care, and health outcomes have continued to persist for lesbian, gay, bisexual, transgender, queer/questioning (LGBTQ) communities. Intersecting marginalized identities such as race, gender, and disability compound health inequities faced by LGBTQ folx. These inequities are not random; rather, they result from deeply embedded homophobia, transphobia, ableism, and racism that pervade the U.S. healthcare system. An exploratory comparative case study was completed using qualitative data collection methods (i.e., key informant interviews, focus groups, and document analysis) to investigate how two California-based Federally Qualified Health Centers (FQHCs) that specialize in …

Becoming Restorative: Discomfort, Praxis, And Ecstasy At The Intersections Of Restorative Practices And Teacher Identity Development, Gwynn Alexander

Dissertations

Restorative justice is inclusive of a philosophy and set of practices that have challenged long-standing paradigms that perpetuate harm in schools. Through this lens, schools are recognized as interconnected communities where the well-being and dignity of all members must be valued. While the restorative movement has demonstrated great promise in cultivating the aims of justice, educators have encountered significant hurdles in their efforts toward transformation. A substantial challenge educators face is to identify effective means through which to disrupt persistent pedagogies of violence in primary and secondary education. This dissertation proposed a pedagogy of transcendence, a framework inclusive of restorative …

Resistencia Indocumentada: Exploring The Lived Experiences Of Higher Education Undocumented Students In The San Diego-Tijuana Border Region, Adan Escobedo Sanchez

Dissertations

Undocumented students face myriad obstacles while attending higher education institutions that would deter them from completing their academic journeys. Furthermore, they are placed with a dual narrative that labels them as either dangerous or exceptional. This study explored the lived experiences of undocumented students in college in the San Diego-Tijuana border region to consider what factors have led to resilience and resistance in their academic journey. By understanding these factors, the research aimed to tackle the dual narrative that burdens undocumented students from the illegality as a master status they possess.

This study used narrative inquiry and a literature review …

Analysis Of One Secondary School's Support Systems For Aspiring First-Generation Latinx College Students: A Case Study, Tiffany Cunningham

Dissertations

U.S. Census Bureau Report (2020c) showed Hispanic students constituted 18.5% of the U.S. population, 36% attended higher education and only 14% completed postsecondary education. Research has shown Hispanic, specifically Latinx, students faced barriers in accessing higher education’s hidden curriculum, compounded by deficit beliefs about their language, culture, and lack of family involvement (Kiyama, 2018; C. Martinez & Mendoza, 2020). Additionally, first-generation college students require college readiness skills, including specialized knowledge about college and measurable and immeasurable skills shown to support student success in college (Chlup et al., 2018; Duncheon, 2021; Morley et al., 2021). Despite secondary school supports like college …

Nursing Education In Complementary Alternative Modalities: A Case Study, Deborah Bird

Dissertations

Purpose: The purpose of this embedded case study was to describe the preparation for and utilization of complimentary alternative modality (CAM) interventions by an experienced Doctor of Nursing Practice (DNP) prepared nurse practitioner (NP) working in an outpatient setting.

Background: Given the widespread use of CAM by the American public and the potential complications involved in combining CAM and standard medical care, a lack of educational preparation in CAM interventions by NPs delivering primary care in outpatient health care settings represents both a potential risk and a missed opportunity to provide holistic patient care. Such a lack of knowledge also …

Effects Of Membrane Components On The Oligomerization Of Amyloid-Β (Aβ) In Alzheimer Disease, Jhinuk Saha

Dissertations

Deposition of extracellular proteinaceous plaques of amyloid-β (Aβ) is one of the major hallmarks of Alzheimer disease (AD). Although, insoluble high molecular fibrils of Aβ are the main constituents of the senile plaques in AD, low molecular weight soluble Aβ oligomers have emerged as the key toxic species involved in memory impairment and neuronal cell death in AD. The process for generation of oligomers can be highly diverse and can involve homotypic interactions of Aβ as well as heterotypic interaction of Aβ with other macromolecules. Previously, the generation of Aβ oligomers with distinct biochemical and biophysical characteristics catalyzed non-esterified fatty …

Connecting Social And Ecological Systems In Small-Scale Fisheries In The Philippines, Sara Eisler Marriott

Dissertations

Nearly 50% of all marine fish capture in the Philippines is from artisanal fisheries, most of which is un- or under-reported. As in many emerging nations around the world, the Philippines cannot fully address overfishing by managing only half of the catch that comes from commercial fisheries. Marine reserves are a popular governance strategy for conservation and of growing interest for fisheries management. Many marine reserves in the Philippines, however, are not considered effective. In 2014, Rare, an international NGO, implemented a community-based management program to increase the effectiveness of the marine reserves, and while it found biomass increased, there …

"If These Walls Could Speak": Judson College And The Formation Of The New Baptist Woman, 1838-1930, E.Gabrielle Walker

Dissertations

Southern Baptist women’s collegiate education and experiences led to their questioning traditional Baptist gender roles and interpreting religion to fit a modern, progressive worldview. Judson College established in 1838 in Marion, Alabama, created a space for its Baptist students to consider socially appropriate ways, outside of doctrinal boundaries, to serve God, themselves, their families, and humanity. Judson remained theologically and culturally conservative, perpetuating inherited religious and social notions of female subordination to men, while increasingly offering students more progressive curricula to meet changing economic and cultural realities. In compliance with white Southern and Baptist conservative values, Judson’s students generally accepted …

Note-Taking In College Mathematics: An Examination Of The Effectiveness Of Guided Notes And Interactive Notebooks On Student Achievement In College Algebra, Verlonda Neal

Dissertations

The purpose of this study was to investigate how the use of interactive guided notes influences the mathematical performance of college algebra students when solving univariate linear equations. The research involved 68 students enrolled in College Algebra at a community college. The participants were divided into two groups: those who took notes using an interactive guided notes method and those who did not use the interactive guided notes note-taking method to cite instructional information. The participants were administered a test on solving univariate linear equations before and after receiving instruction to answer the research questions posed by the study. An …

Weight Change In College Freshmen: Personal, Interpersonal And Situational Influences, Kristin L. Kuhlmann

Dissertations

Obesity has become the most significant noninfectious health risk in the United States, and the major causes of death and disability are shifting to chronic, non-communicable health conditions that are largely attributable to physical inactivity, overweight and obesity, and other diet-related factors. Among children and adolescents, the overweight/obesity rate is approaching 32%, with 17.9% of adolescents becoming obese. While the obesity rate has doubled in all age groups in the United States, it has tripled among young adults aged 18 to 28 years, and 70% of adolescents who are at a healthy weight will become overweight or obese as adults. …

The Experience Of Pediatric Intensive Care Nurses Caring For Dying Children, Rebecca L. Meyer

Dissertations

The purpose of the study was to explore the experience of pediatric nurses caring for dying children. An estimated 55,000 children die every year in the United States and another 400,000 live with life-threatening or life-limiting conditions requiring them to be admitted to the Pediatric Intensive Care Unit (PICU). Nurses who work in this area may have unexplored information and knowledge about the experience itself which could contribute to a better understanding of caring to the nursing profession. Watson's Theory of Human Caring was selected as the framework for the study.

The Effects Of Lecture Capture Design On Student Performance In An Online, Asynchronous Nonmajors Biology Course, Melissa Ann Gutierrez

Dissertations

Lecture capture technology, the ability to provide multimedia recordings of instructional content, has become an essential technology for online learning. One of the ways online courses have tried to appeal to the digital lifestyle of today’s students is providing different lecture capture styles, such as audio (podcasts), video, or interactive videos, due to the popularity of mobile media players providing anytime and anywhere learning. Although lecture capture technology provides educators with a diverse set of tools on how content is delivered, studies have shown mixed results on the impact of lecture capture styles on learning.

For this study, the main …

Predicting Attrition Among Human Anatomy And Physiology I Students In Community Colleges, Benjimen Sessums

Dissertations

Anatomy and Physiology (A&P) courses are offered at almost every postsecondary educational institution in the United States enrolling over 450,000 students each year across the United States with an overall attrition rate between 30-40%. Approximately 150,000 of these students will not be successful the first time they attempt A&P. This constitutes one of the highest attrition rates of all undergraduate degree courses with this size of yearly enrollment.

A&P courses often serve as gateway course required for the continuation and completion of several biological degree fields. Many health-related professional programs such as nursing, paramedicine, and other allied health vocations require …

Faculty Perception Of The Impact Of Covid-19: A Descriptive Case Study Analysis, Traci Pooler

Dissertations

The purpose of this study was to get an understanding of college faculty experiences and perceptions of student learning outcomes during forced virtual instruction in the spring 2020 semester. The study was limited to faculty who taught at one of the 18 member institutions of the Association of Kentucky Colleges and Universities (AIKCU). Factors such as the discipline being taught were considered. Other factors considered were faculty experience with virtual instruction, the availability of technology for faculty and students, and the support provided to students and faculty amid the transition to virtual instruction. The survey reviewed responses from each AIKCU …

Agreement Of Psychiatric Diagnoses Within And Between Groups Of Mental Health Clinicians From Different Disciplines, Wade Mcguire

Dissertations

The development of therapy as a treatment option for mental health problems has led to the creation of different disciplines. Each discipline has developed its own conceptualization of classification and treatment of mental health problems. These conceptualizations have led to different areas of focus for each of the disciplines, specifically counseling, psychology, and social work. The purpose of this study is to investigate whether these areas of focus influence how each discipline diagnoses. For this study, data was collected by having clinicians provide diagnoses for three fictitious clients. The vignettes for the clients were taken from a psychopathology textbook to …

"Can These Bones Live?": The Relationship Between Transformational Leadership And Church Revitalization, Gerald Gifford

Dissertations

This study examined the relationship between Transformational Leadership Theory and church revitalization. The researcher attempted to answer two questions. (1) To what extent do pastors who led Kentucky Baptist Convention churches through a successful revitalization exhibit the characteristics of Transformational Leadership? (2) What, according to the pastors, were the primary causes of the revitalization? The MLQ survey by Mind Garden, Inc. was used to investigate the first question by comparing a target sample with a comparative group who did not lead a revitalization. Scoring on the MLQ confirmed that those in the target sample were transformational leaders. The comparative group, …

Cultivating Community: Investigating Performances Of Community In Ecovillage Settlements, Alex Lockwood

Dissertations

This dissertation considers the subject of ecovillages, intentional ecologically-oriented sustainable communities developed in the U.S., and the different understandings of community involvement, structure, and challenges that members of these communities confront in their efforts at managing these time and labor-intensive settlements. Informed by the work of performance ethnographers and critical phenomenologists, I consider twelve interviews I conducted on-site and electronically with people living in ecovillage settlements. Taking these interviews and my own observations from on-site visits to two ecovillages as entry points, I conducted a phenomenological analysis informed by a critical phenomenological ethos of these accounts, highlighting five motifs that …